Case report: Successful autologous hematopoietic stem cell transplantation in a patient with GAD antibody-spectrum disorder with rapidly progressive dementia

The prevalence of neurological syndromes associated with antibodies to glutamic acid decarboxylase is increasing. While cognitive impairment is a common feature of this condition, it seldom emerges as the primary symptom. In this study, we discuss a case of refractory dementia associated with the gl...
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Autor*in:	Caio César Diniz Disserol [verfasserIn] Dora Pedroso Kowacs [verfasserIn] Samir Kanaan Nabhan [verfasserIn] Hélio Afonso Ghizoni Teive [verfasserIn] Pedro André Kowacs [verfasserIn]

Format:	E-Artikel
Sprache:	Englisch

Erschienen:	2023

Schlagwörter:	autoimmune diseases of the nervous system dementia encephalitis glutamic acid decarboxylase neurocognitive disorders

Übergeordnetes Werk:	In: Frontiers in Neurology - Frontiers Media S.A., 2010, 14(2023)
Übergeordnetes Werk:	volume:14 ; year:2023

Links:	Link aufrufen Link aufrufen Link aufrufen Journal toc

DOI / URN:	10.3389/fneur.2023.1254981

Katalog-ID:	DOAJ091548365

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callnumber-first	R - Medicine
author	Caio César Diniz Disserol
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topic_title	RC346-429 Case report: Successful autologous hematopoietic stem cell transplantation in a patient with GAD antibody-spectrum disorder with rapidly progressive dementia autoimmune diseases of the nervous system dementia encephalitis glutamic acid decarboxylase neurocognitive disorders
topic	misc RC346-429 misc autoimmune diseases of the nervous system misc dementia misc encephalitis misc glutamic acid decarboxylase misc neurocognitive disorders misc Neurology. Diseases of the nervous system
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title	Case report: Successful autologous hematopoietic stem cell transplantation in a patient with GAD antibody-spectrum disorder with rapidly progressive dementia
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title_full	Case report: Successful autologous hematopoietic stem cell transplantation in a patient with GAD antibody-spectrum disorder with rapidly progressive dementia
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author_browse	Caio César Diniz Disserol Dora Pedroso Kowacs Samir Kanaan Nabhan Hélio Afonso Ghizoni Teive Pedro André Kowacs
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title_sort	case report: successful autologous hematopoietic stem cell transplantation in a patient with gad antibody-spectrum disorder with rapidly progressive dementia
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title_auth	Case report: Successful autologous hematopoietic stem cell transplantation in a patient with GAD antibody-spectrum disorder with rapidly progressive dementia
abstract	The prevalence of neurological syndromes associated with antibodies to glutamic acid decarboxylase is increasing. While cognitive impairment is a common feature of this condition, it seldom emerges as the primary symptom. In this study, we discuss a case of refractory dementia associated with the glutamic acid decarboxylase spectrum disorder. Interestingly, this case showed a favorable outcome following autologous hematopoietic stem cell transplantation. We also provide an in-depth review of the current literature on the use of this therapeutic approach for the treatment of this disease.
abstractGer	The prevalence of neurological syndromes associated with antibodies to glutamic acid decarboxylase is increasing. While cognitive impairment is a common feature of this condition, it seldom emerges as the primary symptom. In this study, we discuss a case of refractory dementia associated with the glutamic acid decarboxylase spectrum disorder. Interestingly, this case showed a favorable outcome following autologous hematopoietic stem cell transplantation. We also provide an in-depth review of the current literature on the use of this therapeutic approach for the treatment of this disease.
abstract_unstemmed	The prevalence of neurological syndromes associated with antibodies to glutamic acid decarboxylase is increasing. While cognitive impairment is a common feature of this condition, it seldom emerges as the primary symptom. In this study, we discuss a case of refractory dementia associated with the glutamic acid decarboxylase spectrum disorder. Interestingly, this case showed a favorable outcome following autologous hematopoietic stem cell transplantation. We also provide an in-depth review of the current literature on the use of this therapeutic approach for the treatment of this disease.
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title_short	Case report: Successful autologous hematopoietic stem cell transplantation in a patient with GAD antibody-spectrum disorder with rapidly progressive dementia
url	https://doi.org/10.3389/fneur.2023.1254981 https://doaj.org/article/5dde13c27e5f43a49d08a1e8f8a044f4 https://www.frontiersin.org/articles/10.3389/fneur.2023.1254981/full https://doaj.org/toc/1664-2295
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Case report: Successful autologous hematopoietic stem cell transplantation in a patient with GAD antibody-spectrum disorder with rapidly progressive dementia

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