Case report: Successful autologous hematopoietic stem cell transplantation in a patient with GAD antibody-spectrum disorder with rapidly progressive dementia
The prevalence of neurological syndromes associated with antibodies to glutamic acid decarboxylase is increasing. While cognitive impairment is a common feature of this condition, it seldom emerges as the primary symptom. In this study, we discuss a case of refractory dementia associated with the gl...
Ausführliche Beschreibung
Autor*in: |
Caio César Diniz Disserol [verfasserIn] Dora Pedroso Kowacs [verfasserIn] Samir Kanaan Nabhan [verfasserIn] Hélio Afonso Ghizoni Teive [verfasserIn] Pedro André Kowacs [verfasserIn] |
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E-Artikel |
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Sprache: |
Englisch |
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2023 |
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In: Frontiers in Neurology - Frontiers Media S.A., 2010, 14(2023) |
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Übergeordnetes Werk: |
volume:14 ; year:2023 |
Links: |
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DOI / URN: |
10.3389/fneur.2023.1254981 |
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Katalog-ID: |
DOAJ091548365 |
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10.3389/fneur.2023.1254981 doi (DE-627)DOAJ091548365 (DE-599)DOAJ5dde13c27e5f43a49d08a1e8f8a044f4 DE-627 ger DE-627 rakwb eng RC346-429 Caio César Diniz Disserol verfasserin aut Case report: Successful autologous hematopoietic stem cell transplantation in a patient with GAD antibody-spectrum disorder with rapidly progressive dementia 2023 Text txt rdacontent Computermedien c rdamedia Online-Ressource cr rdacarrier The prevalence of neurological syndromes associated with antibodies to glutamic acid decarboxylase is increasing. While cognitive impairment is a common feature of this condition, it seldom emerges as the primary symptom. In this study, we discuss a case of refractory dementia associated with the glutamic acid decarboxylase spectrum disorder. Interestingly, this case showed a favorable outcome following autologous hematopoietic stem cell transplantation. We also provide an in-depth review of the current literature on the use of this therapeutic approach for the treatment of this disease. autoimmune diseases of the nervous system dementia encephalitis glutamic acid decarboxylase neurocognitive disorders Neurology. Diseases of the nervous system Caio César Diniz Disserol verfasserin aut Dora Pedroso Kowacs verfasserin aut Samir Kanaan Nabhan verfasserin aut Hélio Afonso Ghizoni Teive verfasserin aut Pedro André Kowacs verfasserin aut Pedro André Kowacs verfasserin aut In Frontiers in Neurology Frontiers Media S.A., 2010 14(2023) (DE-627)631498753 (DE-600)2564214-5 16642295 nnns volume:14 year:2023 https://doi.org/10.3389/fneur.2023.1254981 kostenfrei https://doaj.org/article/5dde13c27e5f43a49d08a1e8f8a044f4 kostenfrei https://www.frontiersin.org/articles/10.3389/fneur.2023.1254981/full kostenfrei https://doaj.org/toc/1664-2295 Journal toc kostenfrei GBV_USEFLAG_A SYSFLAG_A GBV_DOAJ GBV_ILN_11 GBV_ILN_20 GBV_ILN_22 GBV_ILN_23 GBV_ILN_24 GBV_ILN_31 GBV_ILN_39 GBV_ILN_40 GBV_ILN_60 GBV_ILN_62 GBV_ILN_63 GBV_ILN_65 GBV_ILN_69 GBV_ILN_73 GBV_ILN_74 GBV_ILN_95 GBV_ILN_105 GBV_ILN_110 GBV_ILN_151 GBV_ILN_161 GBV_ILN_170 GBV_ILN_206 GBV_ILN_213 GBV_ILN_230 GBV_ILN_285 GBV_ILN_293 GBV_ILN_602 GBV_ILN_2003 GBV_ILN_2014 GBV_ILN_4012 GBV_ILN_4037 GBV_ILN_4112 GBV_ILN_4125 GBV_ILN_4126 GBV_ILN_4249 GBV_ILN_4305 GBV_ILN_4306 GBV_ILN_4307 GBV_ILN_4313 GBV_ILN_4322 GBV_ILN_4323 GBV_ILN_4324 GBV_ILN_4325 GBV_ILN_4338 GBV_ILN_4367 GBV_ILN_4700 AR 14 2023 |
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RC346-429 Case report: Successful autologous hematopoietic stem cell transplantation in a patient with GAD antibody-spectrum disorder with rapidly progressive dementia autoimmune diseases of the nervous system dementia encephalitis glutamic acid decarboxylase neurocognitive disorders |
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The prevalence of neurological syndromes associated with antibodies to glutamic acid decarboxylase is increasing. While cognitive impairment is a common feature of this condition, it seldom emerges as the primary symptom. In this study, we discuss a case of refractory dementia associated with the glutamic acid decarboxylase spectrum disorder. Interestingly, this case showed a favorable outcome following autologous hematopoietic stem cell transplantation. We also provide an in-depth review of the current literature on the use of this therapeutic approach for the treatment of this disease. |
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The prevalence of neurological syndromes associated with antibodies to glutamic acid decarboxylase is increasing. While cognitive impairment is a common feature of this condition, it seldom emerges as the primary symptom. In this study, we discuss a case of refractory dementia associated with the glutamic acid decarboxylase spectrum disorder. Interestingly, this case showed a favorable outcome following autologous hematopoietic stem cell transplantation. We also provide an in-depth review of the current literature on the use of this therapeutic approach for the treatment of this disease. |
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The prevalence of neurological syndromes associated with antibodies to glutamic acid decarboxylase is increasing. While cognitive impairment is a common feature of this condition, it seldom emerges as the primary symptom. In this study, we discuss a case of refractory dementia associated with the glutamic acid decarboxylase spectrum disorder. Interestingly, this case showed a favorable outcome following autologous hematopoietic stem cell transplantation. We also provide an in-depth review of the current literature on the use of this therapeutic approach for the treatment of this disease. |
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Case report: Successful autologous hematopoietic stem cell transplantation in a patient with GAD antibody-spectrum disorder with rapidly progressive dementia |
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|
score |
7.3986826 |