Relationship between Dry Eye Disease and Dyslipidemia: A Systematic Review

Background: Dyslipidemia has been suggested to be associated with the occurrence of dry eye disease (DED). However, whether dyslipidemia is responsible for the development of DED remains unclear. In this systematic review, we explored the relationship between DED and dyslipidemia by using quantitati...
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Autor*in:	Tzu-Hao Wang [verfasserIn] Yuan-Jen Tsai [verfasserIn] Yuan-Hung Wang [verfasserIn] Chien-Liang Wu [verfasserIn] I-Chan Lin [verfasserIn]

Format:	E-Artikel
Sprache:	Englisch

Erschienen:	2023

Schlagwörter:	dry eye disease dry eye syndrome dry eye dyslipidemia hyperlipidemia hypercholesterolemia

Übergeordnetes Werk:	In: Journal of Clinical Medicine - MDPI AG, 2013, 12(2023), 6631, p 6631
Übergeordnetes Werk:	volume:12 ; year:2023 ; number:6631, p 6631

Links:	Link aufrufen Link aufrufen Link aufrufen Journal toc

DOI / URN:	10.3390/jcm12206631

Katalog-ID:	DOAJ093125542

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520			\|a Background: Dyslipidemia has been suggested to be associated with the occurrence of dry eye disease (DED). However, whether dyslipidemia is responsible for the development of DED remains unclear. In this systematic review, we explored the relationship between DED and dyslipidemia by using quantitative data. Methods: Following the Preferred Reporting Items for Systematic Reviews and Meta-Analyses guidelines, we conducted a comprehensive literature search in several databases, including PubMed, Embase, Cochrane Library, Web of Science, and Google Scholar, and obtained six relevant studies. Results: Our findings indicated that the majority of the selected studies reported a statistically significant association between dyslipidemia and DED, particularly in women. However, our quantitative analysis revealed that only two studies reported statistically significant differences in total cholesterol and high-density lipoprotein cholesterol values. Conclusion: No statistically significant differences exist in the majority of lipid profile parameters between individuals with and without DED, but there is a statistically significant association between dyslipidemia and DED.
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allfields	10.3390/jcm12206631 doi (DE-627)DOAJ093125542 (DE-599)DOAJa65d119eadac455896223302ac684943 DE-627 ger DE-627 rakwb eng Tzu-Hao Wang verfasserin aut Relationship between Dry Eye Disease and Dyslipidemia: A Systematic Review 2023 Text txt rdacontent Computermedien c rdamedia Online-Ressource cr rdacarrier Background: Dyslipidemia has been suggested to be associated with the occurrence of dry eye disease (DED). However, whether dyslipidemia is responsible for the development of DED remains unclear. In this systematic review, we explored the relationship between DED and dyslipidemia by using quantitative data. Methods: Following the Preferred Reporting Items for Systematic Reviews and Meta-Analyses guidelines, we conducted a comprehensive literature search in several databases, including PubMed, Embase, Cochrane Library, Web of Science, and Google Scholar, and obtained six relevant studies. Results: Our findings indicated that the majority of the selected studies reported a statistically significant association between dyslipidemia and DED, particularly in women. However, our quantitative analysis revealed that only two studies reported statistically significant differences in total cholesterol and high-density lipoprotein cholesterol values. Conclusion: No statistically significant differences exist in the majority of lipid profile parameters between individuals with and without DED, but there is a statistically significant association between dyslipidemia and DED. dry eye disease dry eye syndrome dry eye dyslipidemia hyperlipidemia hypercholesterolemia Medicine R Yuan-Jen Tsai verfasserin aut Yuan-Hung Wang verfasserin aut Chien-Liang Wu verfasserin aut I-Chan Lin verfasserin aut In Journal of Clinical Medicine MDPI AG, 2013 12(2023), 6631, p 6631 (DE-627)718632478 (DE-600)2662592-1 20770383 nnns volume:12 year:2023 number:6631, p 6631 https://doi.org/10.3390/jcm12206631 kostenfrei https://doaj.org/article/a65d119eadac455896223302ac684943 kostenfrei https://www.mdpi.com/2077-0383/12/20/6631 kostenfrei https://doaj.org/toc/2077-0383 Journal toc kostenfrei GBV_USEFLAG_A SYSFLAG_A GBV_DOAJ GBV_ILN_20 GBV_ILN_22 GBV_ILN_23 GBV_ILN_24 GBV_ILN_39 GBV_ILN_40 GBV_ILN_60 GBV_ILN_62 GBV_ILN_63 GBV_ILN_65 GBV_ILN_69 GBV_ILN_73 GBV_ILN_74 GBV_ILN_95 GBV_ILN_105 GBV_ILN_110 GBV_ILN_151 GBV_ILN_161 GBV_ILN_170 GBV_ILN_206 GBV_ILN_213 GBV_ILN_230 GBV_ILN_285 GBV_ILN_293 GBV_ILN_602 GBV_ILN_2005 GBV_ILN_2009 GBV_ILN_2014 GBV_ILN_2055 GBV_ILN_2111 GBV_ILN_4012 GBV_ILN_4037 GBV_ILN_4112 GBV_ILN_4125 GBV_ILN_4126 GBV_ILN_4249 GBV_ILN_4305 GBV_ILN_4306 GBV_ILN_4307 GBV_ILN_4313 GBV_ILN_4322 GBV_ILN_4323 GBV_ILN_4324 GBV_ILN_4325 GBV_ILN_4338 GBV_ILN_4367 GBV_ILN_4700 AR 12 2023 6631, p 6631
spelling	10.3390/jcm12206631 doi (DE-627)DOAJ093125542 (DE-599)DOAJa65d119eadac455896223302ac684943 DE-627 ger DE-627 rakwb eng Tzu-Hao Wang verfasserin aut Relationship between Dry Eye Disease and Dyslipidemia: A Systematic Review 2023 Text txt rdacontent Computermedien c rdamedia Online-Ressource cr rdacarrier Background: Dyslipidemia has been suggested to be associated with the occurrence of dry eye disease (DED). However, whether dyslipidemia is responsible for the development of DED remains unclear. In this systematic review, we explored the relationship between DED and dyslipidemia by using quantitative data. Methods: Following the Preferred Reporting Items for Systematic Reviews and Meta-Analyses guidelines, we conducted a comprehensive literature search in several databases, including PubMed, Embase, Cochrane Library, Web of Science, and Google Scholar, and obtained six relevant studies. Results: Our findings indicated that the majority of the selected studies reported a statistically significant association between dyslipidemia and DED, particularly in women. However, our quantitative analysis revealed that only two studies reported statistically significant differences in total cholesterol and high-density lipoprotein cholesterol values. Conclusion: No statistically significant differences exist in the majority of lipid profile parameters between individuals with and without DED, but there is a statistically significant association between dyslipidemia and DED. dry eye disease dry eye syndrome dry eye dyslipidemia hyperlipidemia hypercholesterolemia Medicine R Yuan-Jen Tsai verfasserin aut Yuan-Hung Wang verfasserin aut Chien-Liang Wu verfasserin aut I-Chan Lin verfasserin aut In Journal of Clinical Medicine MDPI AG, 2013 12(2023), 6631, p 6631 (DE-627)718632478 (DE-600)2662592-1 20770383 nnns volume:12 year:2023 number:6631, p 6631 https://doi.org/10.3390/jcm12206631 kostenfrei https://doaj.org/article/a65d119eadac455896223302ac684943 kostenfrei https://www.mdpi.com/2077-0383/12/20/6631 kostenfrei https://doaj.org/toc/2077-0383 Journal toc kostenfrei GBV_USEFLAG_A SYSFLAG_A GBV_DOAJ GBV_ILN_20 GBV_ILN_22 GBV_ILN_23 GBV_ILN_24 GBV_ILN_39 GBV_ILN_40 GBV_ILN_60 GBV_ILN_62 GBV_ILN_63 GBV_ILN_65 GBV_ILN_69 GBV_ILN_73 GBV_ILN_74 GBV_ILN_95 GBV_ILN_105 GBV_ILN_110 GBV_ILN_151 GBV_ILN_161 GBV_ILN_170 GBV_ILN_206 GBV_ILN_213 GBV_ILN_230 GBV_ILN_285 GBV_ILN_293 GBV_ILN_602 GBV_ILN_2005 GBV_ILN_2009 GBV_ILN_2014 GBV_ILN_2055 GBV_ILN_2111 GBV_ILN_4012 GBV_ILN_4037 GBV_ILN_4112 GBV_ILN_4125 GBV_ILN_4126 GBV_ILN_4249 GBV_ILN_4305 GBV_ILN_4306 GBV_ILN_4307 GBV_ILN_4313 GBV_ILN_4322 GBV_ILN_4323 GBV_ILN_4324 GBV_ILN_4325 GBV_ILN_4338 GBV_ILN_4367 GBV_ILN_4700 AR 12 2023 6631, p 6631
allfields_unstemmed	10.3390/jcm12206631 doi (DE-627)DOAJ093125542 (DE-599)DOAJa65d119eadac455896223302ac684943 DE-627 ger DE-627 rakwb eng Tzu-Hao Wang verfasserin aut Relationship between Dry Eye Disease and Dyslipidemia: A Systematic Review 2023 Text txt rdacontent Computermedien c rdamedia Online-Ressource cr rdacarrier Background: Dyslipidemia has been suggested to be associated with the occurrence of dry eye disease (DED). However, whether dyslipidemia is responsible for the development of DED remains unclear. In this systematic review, we explored the relationship between DED and dyslipidemia by using quantitative data. Methods: Following the Preferred Reporting Items for Systematic Reviews and Meta-Analyses guidelines, we conducted a comprehensive literature search in several databases, including PubMed, Embase, Cochrane Library, Web of Science, and Google Scholar, and obtained six relevant studies. Results: Our findings indicated that the majority of the selected studies reported a statistically significant association between dyslipidemia and DED, particularly in women. However, our quantitative analysis revealed that only two studies reported statistically significant differences in total cholesterol and high-density lipoprotein cholesterol values. Conclusion: No statistically significant differences exist in the majority of lipid profile parameters between individuals with and without DED, but there is a statistically significant association between dyslipidemia and DED. dry eye disease dry eye syndrome dry eye dyslipidemia hyperlipidemia hypercholesterolemia Medicine R Yuan-Jen Tsai verfasserin aut Yuan-Hung Wang verfasserin aut Chien-Liang Wu verfasserin aut I-Chan Lin verfasserin aut In Journal of Clinical Medicine MDPI AG, 2013 12(2023), 6631, p 6631 (DE-627)718632478 (DE-600)2662592-1 20770383 nnns volume:12 year:2023 number:6631, p 6631 https://doi.org/10.3390/jcm12206631 kostenfrei https://doaj.org/article/a65d119eadac455896223302ac684943 kostenfrei https://www.mdpi.com/2077-0383/12/20/6631 kostenfrei https://doaj.org/toc/2077-0383 Journal toc kostenfrei GBV_USEFLAG_A SYSFLAG_A GBV_DOAJ GBV_ILN_20 GBV_ILN_22 GBV_ILN_23 GBV_ILN_24 GBV_ILN_39 GBV_ILN_40 GBV_ILN_60 GBV_ILN_62 GBV_ILN_63 GBV_ILN_65 GBV_ILN_69 GBV_ILN_73 GBV_ILN_74 GBV_ILN_95 GBV_ILN_105 GBV_ILN_110 GBV_ILN_151 GBV_ILN_161 GBV_ILN_170 GBV_ILN_206 GBV_ILN_213 GBV_ILN_230 GBV_ILN_285 GBV_ILN_293 GBV_ILN_602 GBV_ILN_2005 GBV_ILN_2009 GBV_ILN_2014 GBV_ILN_2055 GBV_ILN_2111 GBV_ILN_4012 GBV_ILN_4037 GBV_ILN_4112 GBV_ILN_4125 GBV_ILN_4126 GBV_ILN_4249 GBV_ILN_4305 GBV_ILN_4306 GBV_ILN_4307 GBV_ILN_4313 GBV_ILN_4322 GBV_ILN_4323 GBV_ILN_4324 GBV_ILN_4325 GBV_ILN_4338 GBV_ILN_4367 GBV_ILN_4700 AR 12 2023 6631, p 6631
allfieldsGer	10.3390/jcm12206631 doi (DE-627)DOAJ093125542 (DE-599)DOAJa65d119eadac455896223302ac684943 DE-627 ger DE-627 rakwb eng Tzu-Hao Wang verfasserin aut Relationship between Dry Eye Disease and Dyslipidemia: A Systematic Review 2023 Text txt rdacontent Computermedien c rdamedia Online-Ressource cr rdacarrier Background: Dyslipidemia has been suggested to be associated with the occurrence of dry eye disease (DED). However, whether dyslipidemia is responsible for the development of DED remains unclear. In this systematic review, we explored the relationship between DED and dyslipidemia by using quantitative data. Methods: Following the Preferred Reporting Items for Systematic Reviews and Meta-Analyses guidelines, we conducted a comprehensive literature search in several databases, including PubMed, Embase, Cochrane Library, Web of Science, and Google Scholar, and obtained six relevant studies. Results: Our findings indicated that the majority of the selected studies reported a statistically significant association between dyslipidemia and DED, particularly in women. However, our quantitative analysis revealed that only two studies reported statistically significant differences in total cholesterol and high-density lipoprotein cholesterol values. Conclusion: No statistically significant differences exist in the majority of lipid profile parameters between individuals with and without DED, but there is a statistically significant association between dyslipidemia and DED. dry eye disease dry eye syndrome dry eye dyslipidemia hyperlipidemia hypercholesterolemia Medicine R Yuan-Jen Tsai verfasserin aut Yuan-Hung Wang verfasserin aut Chien-Liang Wu verfasserin aut I-Chan Lin verfasserin aut In Journal of Clinical Medicine MDPI AG, 2013 12(2023), 6631, p 6631 (DE-627)718632478 (DE-600)2662592-1 20770383 nnns volume:12 year:2023 number:6631, p 6631 https://doi.org/10.3390/jcm12206631 kostenfrei https://doaj.org/article/a65d119eadac455896223302ac684943 kostenfrei https://www.mdpi.com/2077-0383/12/20/6631 kostenfrei https://doaj.org/toc/2077-0383 Journal toc kostenfrei GBV_USEFLAG_A SYSFLAG_A GBV_DOAJ GBV_ILN_20 GBV_ILN_22 GBV_ILN_23 GBV_ILN_24 GBV_ILN_39 GBV_ILN_40 GBV_ILN_60 GBV_ILN_62 GBV_ILN_63 GBV_ILN_65 GBV_ILN_69 GBV_ILN_73 GBV_ILN_74 GBV_ILN_95 GBV_ILN_105 GBV_ILN_110 GBV_ILN_151 GBV_ILN_161 GBV_ILN_170 GBV_ILN_206 GBV_ILN_213 GBV_ILN_230 GBV_ILN_285 GBV_ILN_293 GBV_ILN_602 GBV_ILN_2005 GBV_ILN_2009 GBV_ILN_2014 GBV_ILN_2055 GBV_ILN_2111 GBV_ILN_4012 GBV_ILN_4037 GBV_ILN_4112 GBV_ILN_4125 GBV_ILN_4126 GBV_ILN_4249 GBV_ILN_4305 GBV_ILN_4306 GBV_ILN_4307 GBV_ILN_4313 GBV_ILN_4322 GBV_ILN_4323 GBV_ILN_4324 GBV_ILN_4325 GBV_ILN_4338 GBV_ILN_4367 GBV_ILN_4700 AR 12 2023 6631, p 6631
allfieldsSound	10.3390/jcm12206631 doi (DE-627)DOAJ093125542 (DE-599)DOAJa65d119eadac455896223302ac684943 DE-627 ger DE-627 rakwb eng Tzu-Hao Wang verfasserin aut Relationship between Dry Eye Disease and Dyslipidemia: A Systematic Review 2023 Text txt rdacontent Computermedien c rdamedia Online-Ressource cr rdacarrier Background: Dyslipidemia has been suggested to be associated with the occurrence of dry eye disease (DED). However, whether dyslipidemia is responsible for the development of DED remains unclear. In this systematic review, we explored the relationship between DED and dyslipidemia by using quantitative data. Methods: Following the Preferred Reporting Items for Systematic Reviews and Meta-Analyses guidelines, we conducted a comprehensive literature search in several databases, including PubMed, Embase, Cochrane Library, Web of Science, and Google Scholar, and obtained six relevant studies. Results: Our findings indicated that the majority of the selected studies reported a statistically significant association between dyslipidemia and DED, particularly in women. However, our quantitative analysis revealed that only two studies reported statistically significant differences in total cholesterol and high-density lipoprotein cholesterol values. Conclusion: No statistically significant differences exist in the majority of lipid profile parameters between individuals with and without DED, but there is a statistically significant association between dyslipidemia and DED. dry eye disease dry eye syndrome dry eye dyslipidemia hyperlipidemia hypercholesterolemia Medicine R Yuan-Jen Tsai verfasserin aut Yuan-Hung Wang verfasserin aut Chien-Liang Wu verfasserin aut I-Chan Lin verfasserin aut In Journal of Clinical Medicine MDPI AG, 2013 12(2023), 6631, p 6631 (DE-627)718632478 (DE-600)2662592-1 20770383 nnns volume:12 year:2023 number:6631, p 6631 https://doi.org/10.3390/jcm12206631 kostenfrei https://doaj.org/article/a65d119eadac455896223302ac684943 kostenfrei https://www.mdpi.com/2077-0383/12/20/6631 kostenfrei https://doaj.org/toc/2077-0383 Journal toc kostenfrei GBV_USEFLAG_A SYSFLAG_A GBV_DOAJ GBV_ILN_20 GBV_ILN_22 GBV_ILN_23 GBV_ILN_24 GBV_ILN_39 GBV_ILN_40 GBV_ILN_60 GBV_ILN_62 GBV_ILN_63 GBV_ILN_65 GBV_ILN_69 GBV_ILN_73 GBV_ILN_74 GBV_ILN_95 GBV_ILN_105 GBV_ILN_110 GBV_ILN_151 GBV_ILN_161 GBV_ILN_170 GBV_ILN_206 GBV_ILN_213 GBV_ILN_230 GBV_ILN_285 GBV_ILN_293 GBV_ILN_602 GBV_ILN_2005 GBV_ILN_2009 GBV_ILN_2014 GBV_ILN_2055 GBV_ILN_2111 GBV_ILN_4012 GBV_ILN_4037 GBV_ILN_4112 GBV_ILN_4125 GBV_ILN_4126 GBV_ILN_4249 GBV_ILN_4305 GBV_ILN_4306 GBV_ILN_4307 GBV_ILN_4313 GBV_ILN_4322 GBV_ILN_4323 GBV_ILN_4324 GBV_ILN_4325 GBV_ILN_4338 GBV_ILN_4367 GBV_ILN_4700 AR 12 2023 6631, p 6631
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source	In Journal of Clinical Medicine 12(2023), 6631, p 6631 volume:12 year:2023 number:6631, p 6631
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author	Tzu-Hao Wang
spellingShingle	Tzu-Hao Wang misc dry eye disease misc dry eye syndrome misc dry eye misc dyslipidemia misc hyperlipidemia misc hypercholesterolemia misc Medicine misc R Relationship between Dry Eye Disease and Dyslipidemia: A Systematic Review
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topic_title	Relationship between Dry Eye Disease and Dyslipidemia: A Systematic Review dry eye disease dry eye syndrome dry eye dyslipidemia hyperlipidemia hypercholesterolemia
topic	misc dry eye disease misc dry eye syndrome misc dry eye misc dyslipidemia misc hyperlipidemia misc hypercholesterolemia misc Medicine misc R
topic_unstemmed	misc dry eye disease misc dry eye syndrome misc dry eye misc dyslipidemia misc hyperlipidemia misc hypercholesterolemia misc Medicine misc R
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title	Relationship between Dry Eye Disease and Dyslipidemia: A Systematic Review
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title_full	Relationship between Dry Eye Disease and Dyslipidemia: A Systematic Review
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title_sort	relationship between dry eye disease and dyslipidemia: a systematic review
title_auth	Relationship between Dry Eye Disease and Dyslipidemia: A Systematic Review
abstract	Background: Dyslipidemia has been suggested to be associated with the occurrence of dry eye disease (DED). However, whether dyslipidemia is responsible for the development of DED remains unclear. In this systematic review, we explored the relationship between DED and dyslipidemia by using quantitative data. Methods: Following the Preferred Reporting Items for Systematic Reviews and Meta-Analyses guidelines, we conducted a comprehensive literature search in several databases, including PubMed, Embase, Cochrane Library, Web of Science, and Google Scholar, and obtained six relevant studies. Results: Our findings indicated that the majority of the selected studies reported a statistically significant association between dyslipidemia and DED, particularly in women. However, our quantitative analysis revealed that only two studies reported statistically significant differences in total cholesterol and high-density lipoprotein cholesterol values. Conclusion: No statistically significant differences exist in the majority of lipid profile parameters between individuals with and without DED, but there is a statistically significant association between dyslipidemia and DED.
abstractGer	Background: Dyslipidemia has been suggested to be associated with the occurrence of dry eye disease (DED). However, whether dyslipidemia is responsible for the development of DED remains unclear. In this systematic review, we explored the relationship between DED and dyslipidemia by using quantitative data. Methods: Following the Preferred Reporting Items for Systematic Reviews and Meta-Analyses guidelines, we conducted a comprehensive literature search in several databases, including PubMed, Embase, Cochrane Library, Web of Science, and Google Scholar, and obtained six relevant studies. Results: Our findings indicated that the majority of the selected studies reported a statistically significant association between dyslipidemia and DED, particularly in women. However, our quantitative analysis revealed that only two studies reported statistically significant differences in total cholesterol and high-density lipoprotein cholesterol values. Conclusion: No statistically significant differences exist in the majority of lipid profile parameters between individuals with and without DED, but there is a statistically significant association between dyslipidemia and DED.
abstract_unstemmed	Background: Dyslipidemia has been suggested to be associated with the occurrence of dry eye disease (DED). However, whether dyslipidemia is responsible for the development of DED remains unclear. In this systematic review, we explored the relationship between DED and dyslipidemia by using quantitative data. Methods: Following the Preferred Reporting Items for Systematic Reviews and Meta-Analyses guidelines, we conducted a comprehensive literature search in several databases, including PubMed, Embase, Cochrane Library, Web of Science, and Google Scholar, and obtained six relevant studies. Results: Our findings indicated that the majority of the selected studies reported a statistically significant association between dyslipidemia and DED, particularly in women. However, our quantitative analysis revealed that only two studies reported statistically significant differences in total cholesterol and high-density lipoprotein cholesterol values. Conclusion: No statistically significant differences exist in the majority of lipid profile parameters between individuals with and without DED, but there is a statistically significant association between dyslipidemia and DED.
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title_short	Relationship between Dry Eye Disease and Dyslipidemia: A Systematic Review
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