Intravenous Treprostinil in Severe Inoperable Chronic Thromboembolic Pulmonary Hypertension Using Implantable Pumps—Single-Center Experience over More Than a Decade

The management of chronic thromboembolic pulmonary hypertension has significantly changed over the last decade with the availability of both specific therapies and interventional treatments. In parallel, implantable pumps for intravenous administration of treprostinil have broadened the spectrum of...
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Gespeichert in:

Autor*in:	Regina Steringer-Mascherbauer [verfasserIn] Charlotte Huber [verfasserIn] Uwe Fröschl [verfasserIn] Dagmar Engleder [verfasserIn] Reinhold Függer [verfasserIn] Maria Lummersdorfer [verfasserIn] Ralf Lenhard [verfasserIn] Martin Martinek [verfasserIn]

Format:	E-Artikel
Sprache:	Englisch

Erschienen:	2023

Schlagwörter:	chronic thromboembolic pulmonary hypertension implantable pump intravenous treprostinil

Übergeordnetes Werk:	In: Journal of Cardiovascular Development and Disease - MDPI AG, 2014, 10(2023), 8, p 318
Übergeordnetes Werk:	volume:10 ; year:2023 ; number:8, p 318

Links:	Link aufrufen Link aufrufen Link aufrufen Journal toc

DOI / URN:	10.3390/jcdd10080318

Katalog-ID:	DOAJ093601018

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source	In Journal of Cardiovascular Development and Disease 10(2023), 8, p 318 volume:10 year:2023 number:8, p 318
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topic_facet	chronic thromboembolic pulmonary hypertension implantable pump intravenous treprostinil Diseases of the circulatory (Cardiovascular) system
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container_title	Journal of Cardiovascular Development and Disease
authorswithroles_txt_mv	Regina Steringer-Mascherbauer @@aut@@ Charlotte Huber @@aut@@ Uwe Fröschl @@aut@@ Dagmar Engleder @@aut@@ Reinhold Függer @@aut@@ Maria Lummersdorfer @@aut@@ Ralf Lenhard @@aut@@ Martin Martinek @@aut@@
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callnumber-first	R - Medicine
author	Regina Steringer-Mascherbauer
spellingShingle	Regina Steringer-Mascherbauer misc RC666-701 misc chronic thromboembolic pulmonary hypertension misc implantable pump misc intravenous treprostinil misc Diseases of the circulatory (Cardiovascular) system Intravenous Treprostinil in Severe Inoperable Chronic Thromboembolic Pulmonary Hypertension Using Implantable Pumps—Single-Center Experience over More Than a Decade
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topic_title	RC666-701 Intravenous Treprostinil in Severe Inoperable Chronic Thromboembolic Pulmonary Hypertension Using Implantable Pumps—Single-Center Experience over More Than a Decade chronic thromboembolic pulmonary hypertension implantable pump intravenous treprostinil
topic	misc RC666-701 misc chronic thromboembolic pulmonary hypertension misc implantable pump misc intravenous treprostinil misc Diseases of the circulatory (Cardiovascular) system
topic_unstemmed	misc RC666-701 misc chronic thromboembolic pulmonary hypertension misc implantable pump misc intravenous treprostinil misc Diseases of the circulatory (Cardiovascular) system
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title	Intravenous Treprostinil in Severe Inoperable Chronic Thromboembolic Pulmonary Hypertension Using Implantable Pumps—Single-Center Experience over More Than a Decade
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title_full	Intravenous Treprostinil in Severe Inoperable Chronic Thromboembolic Pulmonary Hypertension Using Implantable Pumps—Single-Center Experience over More Than a Decade
author_sort	Regina Steringer-Mascherbauer
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author_browse	Regina Steringer-Mascherbauer Charlotte Huber Uwe Fröschl Dagmar Engleder Reinhold Függer Maria Lummersdorfer Ralf Lenhard Martin Martinek
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title_sort	intravenous treprostinil in severe inoperable chronic thromboembolic pulmonary hypertension using implantable pumps—single-center experience over more than a decade
callnumber	RC666-701
title_auth	Intravenous Treprostinil in Severe Inoperable Chronic Thromboembolic Pulmonary Hypertension Using Implantable Pumps—Single-Center Experience over More Than a Decade
abstract	The management of chronic thromboembolic pulmonary hypertension has significantly changed over the last decade with the availability of both specific therapies and interventional treatments. In parallel, implantable pumps for intravenous administration of treprostinil have broadened the spectrum of continuous prostanoid infusion. We evaluated the course of 17 consecutive patients with inoperable chronic thromboembolic pulmonary hypertension treated with treprostinil by means of an implantable infusion pump between 2011 and 2023 at our center. Complications associated with the infusion system were rare, leading to 0.4 unplanned surgical interventions during 17,160 patient days. No additional safety signals were detected, and clinical benefits achieved with subcutaneous treprostinil before pump implantation could be maintained in all patients. No catheter-related infections or thromboembolic events were observed. Implantable infusion pumps offer an attractive alternative to subcutaneous treprostinil for patients intolerant to the subcutaneous route, including those with chronic thromboembolic pulmonary hypertension.
abstractGer	The management of chronic thromboembolic pulmonary hypertension has significantly changed over the last decade with the availability of both specific therapies and interventional treatments. In parallel, implantable pumps for intravenous administration of treprostinil have broadened the spectrum of continuous prostanoid infusion. We evaluated the course of 17 consecutive patients with inoperable chronic thromboembolic pulmonary hypertension treated with treprostinil by means of an implantable infusion pump between 2011 and 2023 at our center. Complications associated with the infusion system were rare, leading to 0.4 unplanned surgical interventions during 17,160 patient days. No additional safety signals were detected, and clinical benefits achieved with subcutaneous treprostinil before pump implantation could be maintained in all patients. No catheter-related infections or thromboembolic events were observed. Implantable infusion pumps offer an attractive alternative to subcutaneous treprostinil for patients intolerant to the subcutaneous route, including those with chronic thromboembolic pulmonary hypertension.
abstract_unstemmed	The management of chronic thromboembolic pulmonary hypertension has significantly changed over the last decade with the availability of both specific therapies and interventional treatments. In parallel, implantable pumps for intravenous administration of treprostinil have broadened the spectrum of continuous prostanoid infusion. We evaluated the course of 17 consecutive patients with inoperable chronic thromboembolic pulmonary hypertension treated with treprostinil by means of an implantable infusion pump between 2011 and 2023 at our center. Complications associated with the infusion system were rare, leading to 0.4 unplanned surgical interventions during 17,160 patient days. No additional safety signals were detected, and clinical benefits achieved with subcutaneous treprostinil before pump implantation could be maintained in all patients. No catheter-related infections or thromboembolic events were observed. Implantable infusion pumps offer an attractive alternative to subcutaneous treprostinil for patients intolerant to the subcutaneous route, including those with chronic thromboembolic pulmonary hypertension.
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container_issue	8, p 318
title_short	Intravenous Treprostinil in Severe Inoperable Chronic Thromboembolic Pulmonary Hypertension Using Implantable Pumps—Single-Center Experience over More Than a Decade
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author2	Charlotte Huber Uwe Fröschl Dagmar Engleder Reinhold Függer Maria Lummersdorfer Ralf Lenhard Martin Martinek
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up_date	2024-07-03T18:18:01.119Z
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