A Critical Review of Kaempferol in Intestinal Health and Diseases

Kaempferol, a secondary metabolite found in plants, is a naturally occurring flavonoid displaying significant potential in various biological activities. The chemical structure of kaempferol is distinguished by the presence of phenyl rings and four hydroxyl substituents, which make it an exceptional...
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Autor*in:	Jun Chen [verfasserIn] Haopeng Zhong [verfasserIn] Zhouyin Huang [verfasserIn] Xingping Chen [verfasserIn] Jinming You [verfasserIn] Tiande Zou [verfasserIn]

Format:	E-Artikel
Sprache:	Englisch

Erschienen:	2023

Schlagwörter:	antioxidant intestinal barrier function intestinal health intestinal inflammation kaempferol

Übergeordnetes Werk:	In: Antioxidants - MDPI AG, 2013, 12(2023), 8, p 1642
Übergeordnetes Werk:	volume:12 ; year:2023 ; number:8, p 1642

Links:	Link aufrufen Link aufrufen Link aufrufen Journal toc

DOI / URN:	10.3390/antiox12081642

Katalog-ID:	DOAJ09365779X

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allfieldsSound	10.3390/antiox12081642 doi (DE-627)DOAJ09365779X (DE-599)DOAJb7f6d37c2999451b8099a17f01e28cd4 DE-627 ger DE-627 rakwb eng RM1-950 Jun Chen verfasserin aut A Critical Review of Kaempferol in Intestinal Health and Diseases 2023 Text txt rdacontent Computermedien c rdamedia Online-Ressource cr rdacarrier Kaempferol, a secondary metabolite found in plants, is a naturally occurring flavonoid displaying significant potential in various biological activities. The chemical structure of kaempferol is distinguished by the presence of phenyl rings and four hydroxyl substituents, which make it an exceptional radical scavenger. Most recently, an increasing number of studies have demonstrated the significance of kaempferol in the regulation of intestinal function and the mitigation of intestinal inflammation. The focus of the review will primarily be on its impact in terms of antioxidant properties, inflammation, maintenance of intestinal barrier function, and its potential in the treatment of colorectal cancer and obesity. Future research endeavors should additionally give priority to investigating the specific dosage and duration of kaempferol administration for different pathological conditions, while simultaneously conducting deeper investigations into the comprehensible mechanisms of action related to the regulation of aryl hydrocarbon receptor (AhR). This review intends to present novel evidence supporting the utilization of kaempferol in the regulation of gut health and the management of associated diseases. antioxidant intestinal barrier function intestinal health intestinal inflammation kaempferol Therapeutics. Pharmacology Haopeng Zhong verfasserin aut Zhouyin Huang verfasserin aut Xingping Chen verfasserin aut Jinming You verfasserin aut Tiande Zou verfasserin aut In Antioxidants MDPI AG, 2013 12(2023), 8, p 1642 (DE-627)737287578 (DE-600)2704216-9 20763921 nnns volume:12 year:2023 number:8, p 1642 https://doi.org/10.3390/antiox12081642 kostenfrei https://doaj.org/article/b7f6d37c2999451b8099a17f01e28cd4 kostenfrei https://www.mdpi.com/2076-3921/12/8/1642 kostenfrei https://doaj.org/toc/2076-3921 Journal toc kostenfrei GBV_USEFLAG_A SYSFLAG_A GBV_DOAJ GBV_ILN_20 GBV_ILN_22 GBV_ILN_23 GBV_ILN_24 GBV_ILN_39 GBV_ILN_40 GBV_ILN_60 GBV_ILN_62 GBV_ILN_63 GBV_ILN_65 GBV_ILN_69 GBV_ILN_70 GBV_ILN_73 GBV_ILN_74 GBV_ILN_95 GBV_ILN_105 GBV_ILN_110 GBV_ILN_151 GBV_ILN_161 GBV_ILN_170 GBV_ILN_206 GBV_ILN_213 GBV_ILN_230 GBV_ILN_285 GBV_ILN_293 GBV_ILN_602 GBV_ILN_2014 GBV_ILN_4012 GBV_ILN_4037 GBV_ILN_4112 GBV_ILN_4125 GBV_ILN_4126 GBV_ILN_4249 GBV_ILN_4305 GBV_ILN_4306 GBV_ILN_4307 GBV_ILN_4313 GBV_ILN_4322 GBV_ILN_4323 GBV_ILN_4324 GBV_ILN_4325 GBV_ILN_4338 GBV_ILN_4367 GBV_ILN_4700 AR 12 2023 8, p 1642
language	English
source	In Antioxidants 12(2023), 8, p 1642 volume:12 year:2023 number:8, p 1642
sourceStr	In Antioxidants 12(2023), 8, p 1642 volume:12 year:2023 number:8, p 1642
format_phy_str_mv	Article
institution	findex.gbv.de
topic_facet	antioxidant intestinal barrier function intestinal health intestinal inflammation kaempferol Therapeutics. Pharmacology
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container_title	Antioxidants
authorswithroles_txt_mv	Jun Chen @@aut@@ Haopeng Zhong @@aut@@ Zhouyin Huang @@aut@@ Xingping Chen @@aut@@ Jinming You @@aut@@ Tiande Zou @@aut@@
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callnumber-first	R - Medicine
author	Jun Chen
spellingShingle	Jun Chen misc RM1-950 misc antioxidant misc intestinal barrier function misc intestinal health misc intestinal inflammation misc kaempferol misc Therapeutics. Pharmacology A Critical Review of Kaempferol in Intestinal Health and Diseases
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topic_title	RM1-950 A Critical Review of Kaempferol in Intestinal Health and Diseases antioxidant intestinal barrier function intestinal health intestinal inflammation kaempferol
topic	misc RM1-950 misc antioxidant misc intestinal barrier function misc intestinal health misc intestinal inflammation misc kaempferol misc Therapeutics. Pharmacology
topic_unstemmed	misc RM1-950 misc antioxidant misc intestinal barrier function misc intestinal health misc intestinal inflammation misc kaempferol misc Therapeutics. Pharmacology
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title	A Critical Review of Kaempferol in Intestinal Health and Diseases
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abstract	Kaempferol, a secondary metabolite found in plants, is a naturally occurring flavonoid displaying significant potential in various biological activities. The chemical structure of kaempferol is distinguished by the presence of phenyl rings and four hydroxyl substituents, which make it an exceptional radical scavenger. Most recently, an increasing number of studies have demonstrated the significance of kaempferol in the regulation of intestinal function and the mitigation of intestinal inflammation. The focus of the review will primarily be on its impact in terms of antioxidant properties, inflammation, maintenance of intestinal barrier function, and its potential in the treatment of colorectal cancer and obesity. Future research endeavors should additionally give priority to investigating the specific dosage and duration of kaempferol administration for different pathological conditions, while simultaneously conducting deeper investigations into the comprehensible mechanisms of action related to the regulation of aryl hydrocarbon receptor (AhR). This review intends to present novel evidence supporting the utilization of kaempferol in the regulation of gut health and the management of associated diseases.
abstractGer	Kaempferol, a secondary metabolite found in plants, is a naturally occurring flavonoid displaying significant potential in various biological activities. The chemical structure of kaempferol is distinguished by the presence of phenyl rings and four hydroxyl substituents, which make it an exceptional radical scavenger. Most recently, an increasing number of studies have demonstrated the significance of kaempferol in the regulation of intestinal function and the mitigation of intestinal inflammation. The focus of the review will primarily be on its impact in terms of antioxidant properties, inflammation, maintenance of intestinal barrier function, and its potential in the treatment of colorectal cancer and obesity. Future research endeavors should additionally give priority to investigating the specific dosage and duration of kaempferol administration for different pathological conditions, while simultaneously conducting deeper investigations into the comprehensible mechanisms of action related to the regulation of aryl hydrocarbon receptor (AhR). This review intends to present novel evidence supporting the utilization of kaempferol in the regulation of gut health and the management of associated diseases.
abstract_unstemmed	Kaempferol, a secondary metabolite found in plants, is a naturally occurring flavonoid displaying significant potential in various biological activities. The chemical structure of kaempferol is distinguished by the presence of phenyl rings and four hydroxyl substituents, which make it an exceptional radical scavenger. Most recently, an increasing number of studies have demonstrated the significance of kaempferol in the regulation of intestinal function and the mitigation of intestinal inflammation. The focus of the review will primarily be on its impact in terms of antioxidant properties, inflammation, maintenance of intestinal barrier function, and its potential in the treatment of colorectal cancer and obesity. Future research endeavors should additionally give priority to investigating the specific dosage and duration of kaempferol administration for different pathological conditions, while simultaneously conducting deeper investigations into the comprehensible mechanisms of action related to the regulation of aryl hydrocarbon receptor (AhR). This review intends to present novel evidence supporting the utilization of kaempferol in the regulation of gut health and the management of associated diseases.
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title_short	A Critical Review of Kaempferol in Intestinal Health and Diseases
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A Critical Review of Kaempferol in Intestinal Health and Diseases

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