Graves’ Disease after mRNA COVID-19 Vaccination, with the Presence of Autoimmune Antibodies Even One Year Later
A 45-year-old man who had received his second mRNA COVID-19 vaccination one week earlier was presented to the emergency department with chest discomfort. Therefore, we suspected post-vaccination myocarditis; however, the patient showed no signs of myocarditis. After 2 weeks, he revisited the hospita...
Ausführliche Beschreibung
Autor*in: |
Fuminori Nakamura [verfasserIn] Toru Awaya [verfasserIn] Masahiro Ohira [verfasserIn] Yoshinari Enomoto [verfasserIn] Masao Moroi [verfasserIn] Masato Nakamura [verfasserIn] |
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E-Artikel |
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Sprache: |
Englisch |
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2023 |
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Übergeordnetes Werk: |
In: Vaccines - MDPI AG, 2013, 11(2023), 5, p 934 |
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Übergeordnetes Werk: |
volume:11 ; year:2023 ; number:5, p 934 |
Links: |
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DOI / URN: |
10.3390/vaccines11050934 |
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Katalog-ID: |
DOAJ094296065 |
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10.3390/vaccines11050934 doi (DE-627)DOAJ094296065 (DE-599)DOAJ957fef85c0304572a61dc6bab97e251a DE-627 ger DE-627 rakwb eng Fuminori Nakamura verfasserin aut Graves’ Disease after mRNA COVID-19 Vaccination, with the Presence of Autoimmune Antibodies Even One Year Later 2023 Text txt rdacontent Computermedien c rdamedia Online-Ressource cr rdacarrier A 45-year-old man who had received his second mRNA COVID-19 vaccination one week earlier was presented to the emergency department with chest discomfort. Therefore, we suspected post-vaccination myocarditis; however, the patient showed no signs of myocarditis. After 2 weeks, he revisited the hospital complaining of palpitations, hand tremors, and weight loss. The patient exhibited high free thyroxine (FT4) (6.42 ng/dL), low thyroid-stimulating hormone (TSH) (<0.01 μIU/mL), and high TSH receptor antibody (17.5 IU/L) levels, and was diagnosed with Graves’ disease. Thiamazole was administered, and the patient’s FT4 levels normalized after 30 days. One year later, the patient’s FT4 is stable; however, their TSH receptor antibodies have not become negative and thiamazole has continued. This is the first case report to follow the course of Graves’ disease one year after mRNA COVID-19 vaccination. ASIA cross-reactivity Graves’ disease mRNA COVID-19 vaccination Medicine R Toru Awaya verfasserin aut Masahiro Ohira verfasserin aut Yoshinari Enomoto verfasserin aut Masao Moroi verfasserin aut Masato Nakamura verfasserin aut In Vaccines MDPI AG, 2013 11(2023), 5, p 934 (DE-627)736559205 (DE-600)2703319-3 2076393X nnns volume:11 year:2023 number:5, p 934 https://doi.org/10.3390/vaccines11050934 kostenfrei https://doaj.org/article/957fef85c0304572a61dc6bab97e251a kostenfrei https://www.mdpi.com/2076-393X/11/5/934 kostenfrei https://doaj.org/toc/2076-393X Journal toc kostenfrei GBV_USEFLAG_A SYSFLAG_A GBV_DOAJ GBV_ILN_20 GBV_ILN_22 GBV_ILN_23 GBV_ILN_24 GBV_ILN_31 GBV_ILN_39 GBV_ILN_40 GBV_ILN_60 GBV_ILN_62 GBV_ILN_63 GBV_ILN_65 GBV_ILN_69 GBV_ILN_73 GBV_ILN_74 GBV_ILN_95 GBV_ILN_105 GBV_ILN_110 GBV_ILN_151 GBV_ILN_161 GBV_ILN_170 GBV_ILN_206 GBV_ILN_213 GBV_ILN_230 GBV_ILN_285 GBV_ILN_293 GBV_ILN_602 GBV_ILN_2014 GBV_ILN_4012 GBV_ILN_4037 GBV_ILN_4112 GBV_ILN_4125 GBV_ILN_4126 GBV_ILN_4249 GBV_ILN_4305 GBV_ILN_4306 GBV_ILN_4307 GBV_ILN_4313 GBV_ILN_4322 GBV_ILN_4323 GBV_ILN_4324 GBV_ILN_4325 GBV_ILN_4338 GBV_ILN_4367 GBV_ILN_4700 AR 11 2023 5, p 934 |
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10.3390/vaccines11050934 doi (DE-627)DOAJ094296065 (DE-599)DOAJ957fef85c0304572a61dc6bab97e251a DE-627 ger DE-627 rakwb eng Fuminori Nakamura verfasserin aut Graves’ Disease after mRNA COVID-19 Vaccination, with the Presence of Autoimmune Antibodies Even One Year Later 2023 Text txt rdacontent Computermedien c rdamedia Online-Ressource cr rdacarrier A 45-year-old man who had received his second mRNA COVID-19 vaccination one week earlier was presented to the emergency department with chest discomfort. Therefore, we suspected post-vaccination myocarditis; however, the patient showed no signs of myocarditis. After 2 weeks, he revisited the hospital complaining of palpitations, hand tremors, and weight loss. The patient exhibited high free thyroxine (FT4) (6.42 ng/dL), low thyroid-stimulating hormone (TSH) (<0.01 μIU/mL), and high TSH receptor antibody (17.5 IU/L) levels, and was diagnosed with Graves’ disease. Thiamazole was administered, and the patient’s FT4 levels normalized after 30 days. One year later, the patient’s FT4 is stable; however, their TSH receptor antibodies have not become negative and thiamazole has continued. This is the first case report to follow the course of Graves’ disease one year after mRNA COVID-19 vaccination. ASIA cross-reactivity Graves’ disease mRNA COVID-19 vaccination Medicine R Toru Awaya verfasserin aut Masahiro Ohira verfasserin aut Yoshinari Enomoto verfasserin aut Masao Moroi verfasserin aut Masato Nakamura verfasserin aut In Vaccines MDPI AG, 2013 11(2023), 5, p 934 (DE-627)736559205 (DE-600)2703319-3 2076393X nnns volume:11 year:2023 number:5, p 934 https://doi.org/10.3390/vaccines11050934 kostenfrei https://doaj.org/article/957fef85c0304572a61dc6bab97e251a kostenfrei https://www.mdpi.com/2076-393X/11/5/934 kostenfrei https://doaj.org/toc/2076-393X Journal toc kostenfrei GBV_USEFLAG_A SYSFLAG_A GBV_DOAJ GBV_ILN_20 GBV_ILN_22 GBV_ILN_23 GBV_ILN_24 GBV_ILN_31 GBV_ILN_39 GBV_ILN_40 GBV_ILN_60 GBV_ILN_62 GBV_ILN_63 GBV_ILN_65 GBV_ILN_69 GBV_ILN_73 GBV_ILN_74 GBV_ILN_95 GBV_ILN_105 GBV_ILN_110 GBV_ILN_151 GBV_ILN_161 GBV_ILN_170 GBV_ILN_206 GBV_ILN_213 GBV_ILN_230 GBV_ILN_285 GBV_ILN_293 GBV_ILN_602 GBV_ILN_2014 GBV_ILN_4012 GBV_ILN_4037 GBV_ILN_4112 GBV_ILN_4125 GBV_ILN_4126 GBV_ILN_4249 GBV_ILN_4305 GBV_ILN_4306 GBV_ILN_4307 GBV_ILN_4313 GBV_ILN_4322 GBV_ILN_4323 GBV_ILN_4324 GBV_ILN_4325 GBV_ILN_4338 GBV_ILN_4367 GBV_ILN_4700 AR 11 2023 5, p 934 |
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10.3390/vaccines11050934 doi (DE-627)DOAJ094296065 (DE-599)DOAJ957fef85c0304572a61dc6bab97e251a DE-627 ger DE-627 rakwb eng Fuminori Nakamura verfasserin aut Graves’ Disease after mRNA COVID-19 Vaccination, with the Presence of Autoimmune Antibodies Even One Year Later 2023 Text txt rdacontent Computermedien c rdamedia Online-Ressource cr rdacarrier A 45-year-old man who had received his second mRNA COVID-19 vaccination one week earlier was presented to the emergency department with chest discomfort. Therefore, we suspected post-vaccination myocarditis; however, the patient showed no signs of myocarditis. After 2 weeks, he revisited the hospital complaining of palpitations, hand tremors, and weight loss. The patient exhibited high free thyroxine (FT4) (6.42 ng/dL), low thyroid-stimulating hormone (TSH) (<0.01 μIU/mL), and high TSH receptor antibody (17.5 IU/L) levels, and was diagnosed with Graves’ disease. Thiamazole was administered, and the patient’s FT4 levels normalized after 30 days. One year later, the patient’s FT4 is stable; however, their TSH receptor antibodies have not become negative and thiamazole has continued. This is the first case report to follow the course of Graves’ disease one year after mRNA COVID-19 vaccination. ASIA cross-reactivity Graves’ disease mRNA COVID-19 vaccination Medicine R Toru Awaya verfasserin aut Masahiro Ohira verfasserin aut Yoshinari Enomoto verfasserin aut Masao Moroi verfasserin aut Masato Nakamura verfasserin aut In Vaccines MDPI AG, 2013 11(2023), 5, p 934 (DE-627)736559205 (DE-600)2703319-3 2076393X nnns volume:11 year:2023 number:5, p 934 https://doi.org/10.3390/vaccines11050934 kostenfrei https://doaj.org/article/957fef85c0304572a61dc6bab97e251a kostenfrei https://www.mdpi.com/2076-393X/11/5/934 kostenfrei https://doaj.org/toc/2076-393X Journal toc kostenfrei GBV_USEFLAG_A SYSFLAG_A GBV_DOAJ GBV_ILN_20 GBV_ILN_22 GBV_ILN_23 GBV_ILN_24 GBV_ILN_31 GBV_ILN_39 GBV_ILN_40 GBV_ILN_60 GBV_ILN_62 GBV_ILN_63 GBV_ILN_65 GBV_ILN_69 GBV_ILN_73 GBV_ILN_74 GBV_ILN_95 GBV_ILN_105 GBV_ILN_110 GBV_ILN_151 GBV_ILN_161 GBV_ILN_170 GBV_ILN_206 GBV_ILN_213 GBV_ILN_230 GBV_ILN_285 GBV_ILN_293 GBV_ILN_602 GBV_ILN_2014 GBV_ILN_4012 GBV_ILN_4037 GBV_ILN_4112 GBV_ILN_4125 GBV_ILN_4126 GBV_ILN_4249 GBV_ILN_4305 GBV_ILN_4306 GBV_ILN_4307 GBV_ILN_4313 GBV_ILN_4322 GBV_ILN_4323 GBV_ILN_4324 GBV_ILN_4325 GBV_ILN_4338 GBV_ILN_4367 GBV_ILN_4700 AR 11 2023 5, p 934 |
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10.3390/vaccines11050934 doi (DE-627)DOAJ094296065 (DE-599)DOAJ957fef85c0304572a61dc6bab97e251a DE-627 ger DE-627 rakwb eng Fuminori Nakamura verfasserin aut Graves’ Disease after mRNA COVID-19 Vaccination, with the Presence of Autoimmune Antibodies Even One Year Later 2023 Text txt rdacontent Computermedien c rdamedia Online-Ressource cr rdacarrier A 45-year-old man who had received his second mRNA COVID-19 vaccination one week earlier was presented to the emergency department with chest discomfort. Therefore, we suspected post-vaccination myocarditis; however, the patient showed no signs of myocarditis. After 2 weeks, he revisited the hospital complaining of palpitations, hand tremors, and weight loss. The patient exhibited high free thyroxine (FT4) (6.42 ng/dL), low thyroid-stimulating hormone (TSH) (<0.01 μIU/mL), and high TSH receptor antibody (17.5 IU/L) levels, and was diagnosed with Graves’ disease. Thiamazole was administered, and the patient’s FT4 levels normalized after 30 days. One year later, the patient’s FT4 is stable; however, their TSH receptor antibodies have not become negative and thiamazole has continued. This is the first case report to follow the course of Graves’ disease one year after mRNA COVID-19 vaccination. ASIA cross-reactivity Graves’ disease mRNA COVID-19 vaccination Medicine R Toru Awaya verfasserin aut Masahiro Ohira verfasserin aut Yoshinari Enomoto verfasserin aut Masao Moroi verfasserin aut Masato Nakamura verfasserin aut In Vaccines MDPI AG, 2013 11(2023), 5, p 934 (DE-627)736559205 (DE-600)2703319-3 2076393X nnns volume:11 year:2023 number:5, p 934 https://doi.org/10.3390/vaccines11050934 kostenfrei https://doaj.org/article/957fef85c0304572a61dc6bab97e251a kostenfrei https://www.mdpi.com/2076-393X/11/5/934 kostenfrei https://doaj.org/toc/2076-393X Journal toc kostenfrei GBV_USEFLAG_A SYSFLAG_A GBV_DOAJ GBV_ILN_20 GBV_ILN_22 GBV_ILN_23 GBV_ILN_24 GBV_ILN_31 GBV_ILN_39 GBV_ILN_40 GBV_ILN_60 GBV_ILN_62 GBV_ILN_63 GBV_ILN_65 GBV_ILN_69 GBV_ILN_73 GBV_ILN_74 GBV_ILN_95 GBV_ILN_105 GBV_ILN_110 GBV_ILN_151 GBV_ILN_161 GBV_ILN_170 GBV_ILN_206 GBV_ILN_213 GBV_ILN_230 GBV_ILN_285 GBV_ILN_293 GBV_ILN_602 GBV_ILN_2014 GBV_ILN_4012 GBV_ILN_4037 GBV_ILN_4112 GBV_ILN_4125 GBV_ILN_4126 GBV_ILN_4249 GBV_ILN_4305 GBV_ILN_4306 GBV_ILN_4307 GBV_ILN_4313 GBV_ILN_4322 GBV_ILN_4323 GBV_ILN_4324 GBV_ILN_4325 GBV_ILN_4338 GBV_ILN_4367 GBV_ILN_4700 AR 11 2023 5, p 934 |
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10.3390/vaccines11050934 doi (DE-627)DOAJ094296065 (DE-599)DOAJ957fef85c0304572a61dc6bab97e251a DE-627 ger DE-627 rakwb eng Fuminori Nakamura verfasserin aut Graves’ Disease after mRNA COVID-19 Vaccination, with the Presence of Autoimmune Antibodies Even One Year Later 2023 Text txt rdacontent Computermedien c rdamedia Online-Ressource cr rdacarrier A 45-year-old man who had received his second mRNA COVID-19 vaccination one week earlier was presented to the emergency department with chest discomfort. Therefore, we suspected post-vaccination myocarditis; however, the patient showed no signs of myocarditis. After 2 weeks, he revisited the hospital complaining of palpitations, hand tremors, and weight loss. The patient exhibited high free thyroxine (FT4) (6.42 ng/dL), low thyroid-stimulating hormone (TSH) (<0.01 μIU/mL), and high TSH receptor antibody (17.5 IU/L) levels, and was diagnosed with Graves’ disease. Thiamazole was administered, and the patient’s FT4 levels normalized after 30 days. One year later, the patient’s FT4 is stable; however, their TSH receptor antibodies have not become negative and thiamazole has continued. This is the first case report to follow the course of Graves’ disease one year after mRNA COVID-19 vaccination. ASIA cross-reactivity Graves’ disease mRNA COVID-19 vaccination Medicine R Toru Awaya verfasserin aut Masahiro Ohira verfasserin aut Yoshinari Enomoto verfasserin aut Masao Moroi verfasserin aut Masato Nakamura verfasserin aut In Vaccines MDPI AG, 2013 11(2023), 5, p 934 (DE-627)736559205 (DE-600)2703319-3 2076393X nnns volume:11 year:2023 number:5, p 934 https://doi.org/10.3390/vaccines11050934 kostenfrei https://doaj.org/article/957fef85c0304572a61dc6bab97e251a kostenfrei https://www.mdpi.com/2076-393X/11/5/934 kostenfrei https://doaj.org/toc/2076-393X Journal toc kostenfrei GBV_USEFLAG_A SYSFLAG_A GBV_DOAJ GBV_ILN_20 GBV_ILN_22 GBV_ILN_23 GBV_ILN_24 GBV_ILN_31 GBV_ILN_39 GBV_ILN_40 GBV_ILN_60 GBV_ILN_62 GBV_ILN_63 GBV_ILN_65 GBV_ILN_69 GBV_ILN_73 GBV_ILN_74 GBV_ILN_95 GBV_ILN_105 GBV_ILN_110 GBV_ILN_151 GBV_ILN_161 GBV_ILN_170 GBV_ILN_206 GBV_ILN_213 GBV_ILN_230 GBV_ILN_285 GBV_ILN_293 GBV_ILN_602 GBV_ILN_2014 GBV_ILN_4012 GBV_ILN_4037 GBV_ILN_4112 GBV_ILN_4125 GBV_ILN_4126 GBV_ILN_4249 GBV_ILN_4305 GBV_ILN_4306 GBV_ILN_4307 GBV_ILN_4313 GBV_ILN_4322 GBV_ILN_4323 GBV_ILN_4324 GBV_ILN_4325 GBV_ILN_4338 GBV_ILN_4367 GBV_ILN_4700 AR 11 2023 5, p 934 |
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Graves’ Disease after mRNA COVID-19 Vaccination, with the Presence of Autoimmune Antibodies Even One Year Later ASIA cross-reactivity Graves’ disease mRNA COVID-19 vaccination |
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graves’ disease after mrna covid-19 vaccination, with the presence of autoimmune antibodies even one year later |
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Graves’ Disease after mRNA COVID-19 Vaccination, with the Presence of Autoimmune Antibodies Even One Year Later |
abstract |
A 45-year-old man who had received his second mRNA COVID-19 vaccination one week earlier was presented to the emergency department with chest discomfort. Therefore, we suspected post-vaccination myocarditis; however, the patient showed no signs of myocarditis. After 2 weeks, he revisited the hospital complaining of palpitations, hand tremors, and weight loss. The patient exhibited high free thyroxine (FT4) (6.42 ng/dL), low thyroid-stimulating hormone (TSH) (<0.01 μIU/mL), and high TSH receptor antibody (17.5 IU/L) levels, and was diagnosed with Graves’ disease. Thiamazole was administered, and the patient’s FT4 levels normalized after 30 days. One year later, the patient’s FT4 is stable; however, their TSH receptor antibodies have not become negative and thiamazole has continued. This is the first case report to follow the course of Graves’ disease one year after mRNA COVID-19 vaccination. |
abstractGer |
A 45-year-old man who had received his second mRNA COVID-19 vaccination one week earlier was presented to the emergency department with chest discomfort. Therefore, we suspected post-vaccination myocarditis; however, the patient showed no signs of myocarditis. After 2 weeks, he revisited the hospital complaining of palpitations, hand tremors, and weight loss. The patient exhibited high free thyroxine (FT4) (6.42 ng/dL), low thyroid-stimulating hormone (TSH) (<0.01 μIU/mL), and high TSH receptor antibody (17.5 IU/L) levels, and was diagnosed with Graves’ disease. Thiamazole was administered, and the patient’s FT4 levels normalized after 30 days. One year later, the patient’s FT4 is stable; however, their TSH receptor antibodies have not become negative and thiamazole has continued. This is the first case report to follow the course of Graves’ disease one year after mRNA COVID-19 vaccination. |
abstract_unstemmed |
A 45-year-old man who had received his second mRNA COVID-19 vaccination one week earlier was presented to the emergency department with chest discomfort. Therefore, we suspected post-vaccination myocarditis; however, the patient showed no signs of myocarditis. After 2 weeks, he revisited the hospital complaining of palpitations, hand tremors, and weight loss. The patient exhibited high free thyroxine (FT4) (6.42 ng/dL), low thyroid-stimulating hormone (TSH) (<0.01 μIU/mL), and high TSH receptor antibody (17.5 IU/L) levels, and was diagnosed with Graves’ disease. Thiamazole was administered, and the patient’s FT4 levels normalized after 30 days. One year later, the patient’s FT4 is stable; however, their TSH receptor antibodies have not become negative and thiamazole has continued. This is the first case report to follow the course of Graves’ disease one year after mRNA COVID-19 vaccination. |
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title_short |
Graves’ Disease after mRNA COVID-19 Vaccination, with the Presence of Autoimmune Antibodies Even One Year Later |
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