Lifestyle intervention on psychotherapy and exercise and their effect on physical and psychological health in outpatients with schizophrenia spectrum disorders. A pragmatic clinical trial

Introduction Patients with Schizophrenia Spectrum Disorders (SSD) often lead unhealthy lifestyles with higher prevalence of obesity and unfavourable cardiometabolic parameters with less life expectancy and often worse quality of life compared with general population. Objectives Evaluate the effectiveness of a combined intervention of exercise and psychoeducation in 48 SSD outpatients with metabolic syndrome (MetS), treated with second-generation antipsychotics and also aimed to explore if the effect persisted in a long-term follow-up of 24 months. Methods The intervention included a 12-week aerobic exercise program and a session of lifestyle psychoeducation. Effectiveness was measured in terms a wide range of outcomes involving physical and psychological health, functioning, quality of life, physical activity and changes in motivation to exercise in the context of the self-determination theory. Results The active intervention group showed benefits after Bonferroni correction over clinical global impression, identified motivation to exercise and changes of physical activity pattern. Maintenance of effects after 24 months of follow-up was observed for identified regulation to exercise and also for negative symptoms of psychosis (Table). Table. Effects assigned-group/time-over *p≤0.05 **p≤0.01. Variables 12weeks 24months Time Groupxtime Groupx timex gender p p p p p HDL (mg/dl) 0.021* Negative Syndrome Scale 0.044* 0.004** BREQ-2- Extrinsic regulation 0.008** 0.004** -External 0.026* -Introyected 0.038* -Identified 0.018* 0.015* 0.003** 0.002** BREQ-2-Intrinsic regulation 0.005** 0.004** Pedometer (steps/day) 0.001** 0.006** Conclusions A combined intervention on SSD outpatients with MetS showed effectiveness over several clinical parameters and functioning. Therefore, should be considered an essential part of the integral treatment in mental health services for SSD patients. Disclosure No significant relationships. Ausführliche Beschreibung

Gespeichert in:

Autor*in:	B. Fernández-Abascal [verfasserIn] P. Suárez-Pinilla [verfasserIn] C. Cobo-Corrales [verfasserIn] B. Crespo-Facorro [verfasserIn] M. Suarez-Pinilla [verfasserIn]

Format:	E-Artikel
Sprache:	Englisch

Erschienen:	2022

Schlagwörter:	non-affective psychosis, exercise Quality of Life cardiometabolic risk

Übergeordnetes Werk:	In: European Psychiatry - Cambridge University Press, 2020, 65(2022), Seite S130-S131
Übergeordnetes Werk:	volume:65 ; year:2022 ; pages:S130-S131

Links:	Link aufrufen Link aufrufen Link aufrufen Journal toc Journal toc

DOI / URN:	10.1192/j.eurpsy.2022.357

Katalog-ID:	DOAJ094633762

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520			\|a Introduction Patients with Schizophrenia Spectrum Disorders (SSD) often lead unhealthy lifestyles with higher prevalence of obesity and unfavourable cardiometabolic parameters with less life expectancy and often worse quality of life compared with general population. Objectives Evaluate the effectiveness of a combined intervention of exercise and psychoeducation in 48 SSD outpatients with metabolic syndrome (MetS), treated with second-generation antipsychotics and also aimed to explore if the effect persisted in a long-term follow-up of 24 months. Methods The intervention included a 12-week aerobic exercise program and a session of lifestyle psychoeducation. Effectiveness was measured in terms a wide range of outcomes involving physical and psychological health, functioning, quality of life, physical activity and changes in motivation to exercise in the context of the self-determination theory. Results The active intervention group showed benefits after Bonferroni correction over clinical global impression, identified motivation to exercise and changes of physical activity pattern. Maintenance of effects after 24 months of follow-up was observed for identified regulation to exercise and also for negative symptoms of psychosis (Table). Table. Effects assigned-group/time-over p≤0.05 p≤0.01. Variables 12weeks 24months Time Groupxtime Groupx timex gender p p p p p HDL (mg/dl) 0.021 Negative Syndrome Scale 0.044* 0.004 BREQ-2- Extrinsic regulation 0.008 0.004** -External 0.026* -Introyected 0.038* -Identified 0.018* 0.015* 0.003 0.002 BREQ-2-Intrinsic regulation 0.005 0.004 Pedometer (steps/day) 0.001 0.006 Conclusions A combined intervention on SSD outpatients with MetS showed effectiveness over several clinical parameters and functioning. Therefore, should be considered an essential part of the integral treatment in mental health services for SSD patients. Disclosure No significant relationships.
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allfields_unstemmed	10.1192/j.eurpsy.2022.357 doi (DE-627)DOAJ094633762 (DE-599)DOAJae2b6adc13ac4043ab6d930d0e7fef42 DE-627 ger DE-627 rakwb eng RC435-571 B. Fernández-Abascal verfasserin aut Lifestyle intervention on psychotherapy and exercise and their effect on physical and psychological health in outpatients with schizophrenia spectrum disorders. A pragmatic clinical trial 2022 Text txt rdacontent Computermedien c rdamedia Online-Ressource cr rdacarrier Introduction Patients with Schizophrenia Spectrum Disorders (SSD) often lead unhealthy lifestyles with higher prevalence of obesity and unfavourable cardiometabolic parameters with less life expectancy and often worse quality of life compared with general population. Objectives Evaluate the effectiveness of a combined intervention of exercise and psychoeducation in 48 SSD outpatients with metabolic syndrome (MetS), treated with second-generation antipsychotics and also aimed to explore if the effect persisted in a long-term follow-up of 24 months. Methods The intervention included a 12-week aerobic exercise program and a session of lifestyle psychoeducation. Effectiveness was measured in terms a wide range of outcomes involving physical and psychological health, functioning, quality of life, physical activity and changes in motivation to exercise in the context of the self-determination theory. Results The active intervention group showed benefits after Bonferroni correction over clinical global impression, identified motivation to exercise and changes of physical activity pattern. Maintenance of effects after 24 months of follow-up was observed for identified regulation to exercise and also for negative symptoms of psychosis (Table). Table. Effects assigned-group/time-over p≤0.05 p≤0.01. Variables 12weeks 24months Time Groupxtime Groupx timex gender p p p p p HDL (mg/dl) 0.021 Negative Syndrome Scale 0.044* 0.004 BREQ-2- Extrinsic regulation 0.008 0.004** -External 0.026* -Introyected 0.038* -Identified 0.018* 0.015* 0.003 0.002 BREQ-2-Intrinsic regulation 0.005 0.004 Pedometer (steps/day) 0.001 0.006 Conclusions A combined intervention on SSD outpatients with MetS showed effectiveness over several clinical parameters and functioning. Therefore, should be considered an essential part of the integral treatment in mental health services for SSD patients. Disclosure No significant relationships. non-affective psychosis, exercise Quality of Life cardiometabolic risk Psychiatry P. Suárez-Pinilla verfasserin aut C. Cobo-Corrales verfasserin aut B. Crespo-Facorro verfasserin aut M. Suarez-Pinilla verfasserin aut In European Psychiatry Cambridge University Press, 2020 65(2022), Seite S130-S131 (DE-627)320445070 (DE-600)2005377-0 17783585 nnns volume:65 year:2022 pages:S130-S131 https://doi.org/10.1192/j.eurpsy.2022.357 kostenfrei https://doaj.org/article/ae2b6adc13ac4043ab6d930d0e7fef42 kostenfrei https://www.cambridge.org/core/product/identifier/S0924933822003571/type/journal_article kostenfrei https://doaj.org/toc/0924-9338 Journal toc kostenfrei https://doaj.org/toc/1778-3585 Journal toc kostenfrei GBV_USEFLAG_A SYSFLAG_A GBV_DOAJ GBV_ILN_20 GBV_ILN_22 GBV_ILN_23 GBV_ILN_24 GBV_ILN_31 GBV_ILN_39 GBV_ILN_40 GBV_ILN_60 GBV_ILN_62 GBV_ILN_63 GBV_ILN_65 GBV_ILN_69 GBV_ILN_73 GBV_ILN_74 GBV_ILN_95 GBV_ILN_105 GBV_ILN_110 GBV_ILN_151 GBV_ILN_161 GBV_ILN_170 GBV_ILN_206 GBV_ILN_213 GBV_ILN_217 GBV_ILN_230 GBV_ILN_285 GBV_ILN_293 GBV_ILN_374 GBV_ILN_602 GBV_ILN_636 GBV_ILN_2004 GBV_ILN_2014 GBV_ILN_2110 GBV_ILN_2336 GBV_ILN_2470 GBV_ILN_4012 GBV_ILN_4037 GBV_ILN_4112 GBV_ILN_4125 GBV_ILN_4126 GBV_ILN_4249 GBV_ILN_4305 GBV_ILN_4306 GBV_ILN_4307 GBV_ILN_4313 GBV_ILN_4322 GBV_ILN_4323 GBV_ILN_4324 GBV_ILN_4325 GBV_ILN_4338 GBV_ILN_4367 GBV_ILN_4700 AR 65 2022 S130-S131
allfieldsGer	10.1192/j.eurpsy.2022.357 doi (DE-627)DOAJ094633762 (DE-599)DOAJae2b6adc13ac4043ab6d930d0e7fef42 DE-627 ger DE-627 rakwb eng RC435-571 B. Fernández-Abascal verfasserin aut Lifestyle intervention on psychotherapy and exercise and their effect on physical and psychological health in outpatients with schizophrenia spectrum disorders. A pragmatic clinical trial 2022 Text txt rdacontent Computermedien c rdamedia Online-Ressource cr rdacarrier Introduction Patients with Schizophrenia Spectrum Disorders (SSD) often lead unhealthy lifestyles with higher prevalence of obesity and unfavourable cardiometabolic parameters with less life expectancy and often worse quality of life compared with general population. Objectives Evaluate the effectiveness of a combined intervention of exercise and psychoeducation in 48 SSD outpatients with metabolic syndrome (MetS), treated with second-generation antipsychotics and also aimed to explore if the effect persisted in a long-term follow-up of 24 months. Methods The intervention included a 12-week aerobic exercise program and a session of lifestyle psychoeducation. Effectiveness was measured in terms a wide range of outcomes involving physical and psychological health, functioning, quality of life, physical activity and changes in motivation to exercise in the context of the self-determination theory. Results The active intervention group showed benefits after Bonferroni correction over clinical global impression, identified motivation to exercise and changes of physical activity pattern. Maintenance of effects after 24 months of follow-up was observed for identified regulation to exercise and also for negative symptoms of psychosis (Table). Table. Effects assigned-group/time-over p≤0.05 p≤0.01. Variables 12weeks 24months Time Groupxtime Groupx timex gender p p p p p HDL (mg/dl) 0.021 Negative Syndrome Scale 0.044* 0.004 BREQ-2- Extrinsic regulation 0.008 0.004** -External 0.026* -Introyected 0.038* -Identified 0.018* 0.015* 0.003 0.002 BREQ-2-Intrinsic regulation 0.005 0.004 Pedometer (steps/day) 0.001 0.006 Conclusions A combined intervention on SSD outpatients with MetS showed effectiveness over several clinical parameters and functioning. Therefore, should be considered an essential part of the integral treatment in mental health services for SSD patients. Disclosure No significant relationships. non-affective psychosis, exercise Quality of Life cardiometabolic risk Psychiatry P. Suárez-Pinilla verfasserin aut C. Cobo-Corrales verfasserin aut B. Crespo-Facorro verfasserin aut M. Suarez-Pinilla verfasserin aut In European Psychiatry Cambridge University Press, 2020 65(2022), Seite S130-S131 (DE-627)320445070 (DE-600)2005377-0 17783585 nnns volume:65 year:2022 pages:S130-S131 https://doi.org/10.1192/j.eurpsy.2022.357 kostenfrei https://doaj.org/article/ae2b6adc13ac4043ab6d930d0e7fef42 kostenfrei https://www.cambridge.org/core/product/identifier/S0924933822003571/type/journal_article kostenfrei https://doaj.org/toc/0924-9338 Journal toc kostenfrei https://doaj.org/toc/1778-3585 Journal toc kostenfrei GBV_USEFLAG_A SYSFLAG_A GBV_DOAJ GBV_ILN_20 GBV_ILN_22 GBV_ILN_23 GBV_ILN_24 GBV_ILN_31 GBV_ILN_39 GBV_ILN_40 GBV_ILN_60 GBV_ILN_62 GBV_ILN_63 GBV_ILN_65 GBV_ILN_69 GBV_ILN_73 GBV_ILN_74 GBV_ILN_95 GBV_ILN_105 GBV_ILN_110 GBV_ILN_151 GBV_ILN_161 GBV_ILN_170 GBV_ILN_206 GBV_ILN_213 GBV_ILN_217 GBV_ILN_230 GBV_ILN_285 GBV_ILN_293 GBV_ILN_374 GBV_ILN_602 GBV_ILN_636 GBV_ILN_2004 GBV_ILN_2014 GBV_ILN_2110 GBV_ILN_2336 GBV_ILN_2470 GBV_ILN_4012 GBV_ILN_4037 GBV_ILN_4112 GBV_ILN_4125 GBV_ILN_4126 GBV_ILN_4249 GBV_ILN_4305 GBV_ILN_4306 GBV_ILN_4307 GBV_ILN_4313 GBV_ILN_4322 GBV_ILN_4323 GBV_ILN_4324 GBV_ILN_4325 GBV_ILN_4338 GBV_ILN_4367 GBV_ILN_4700 AR 65 2022 S130-S131
allfieldsSound	10.1192/j.eurpsy.2022.357 doi (DE-627)DOAJ094633762 (DE-599)DOAJae2b6adc13ac4043ab6d930d0e7fef42 DE-627 ger DE-627 rakwb eng RC435-571 B. Fernández-Abascal verfasserin aut Lifestyle intervention on psychotherapy and exercise and their effect on physical and psychological health in outpatients with schizophrenia spectrum disorders. A pragmatic clinical trial 2022 Text txt rdacontent Computermedien c rdamedia Online-Ressource cr rdacarrier Introduction Patients with Schizophrenia Spectrum Disorders (SSD) often lead unhealthy lifestyles with higher prevalence of obesity and unfavourable cardiometabolic parameters with less life expectancy and often worse quality of life compared with general population. Objectives Evaluate the effectiveness of a combined intervention of exercise and psychoeducation in 48 SSD outpatients with metabolic syndrome (MetS), treated with second-generation antipsychotics and also aimed to explore if the effect persisted in a long-term follow-up of 24 months. Methods The intervention included a 12-week aerobic exercise program and a session of lifestyle psychoeducation. Effectiveness was measured in terms a wide range of outcomes involving physical and psychological health, functioning, quality of life, physical activity and changes in motivation to exercise in the context of the self-determination theory. Results The active intervention group showed benefits after Bonferroni correction over clinical global impression, identified motivation to exercise and changes of physical activity pattern. Maintenance of effects after 24 months of follow-up was observed for identified regulation to exercise and also for negative symptoms of psychosis (Table). Table. Effects assigned-group/time-over p≤0.05 p≤0.01. Variables 12weeks 24months Time Groupxtime Groupx timex gender p p p p p HDL (mg/dl) 0.021 Negative Syndrome Scale 0.044* 0.004 BREQ-2- Extrinsic regulation 0.008 0.004** -External 0.026* -Introyected 0.038* -Identified 0.018* 0.015* 0.003 0.002 BREQ-2-Intrinsic regulation 0.005 0.004 Pedometer (steps/day) 0.001 0.006 Conclusions A combined intervention on SSD outpatients with MetS showed effectiveness over several clinical parameters and functioning. Therefore, should be considered an essential part of the integral treatment in mental health services for SSD patients. Disclosure No significant relationships. non-affective psychosis, exercise Quality of Life cardiometabolic risk Psychiatry P. Suárez-Pinilla verfasserin aut C. Cobo-Corrales verfasserin aut B. Crespo-Facorro verfasserin aut M. Suarez-Pinilla verfasserin aut In European Psychiatry Cambridge University Press, 2020 65(2022), Seite S130-S131 (DE-627)320445070 (DE-600)2005377-0 17783585 nnns volume:65 year:2022 pages:S130-S131 https://doi.org/10.1192/j.eurpsy.2022.357 kostenfrei https://doaj.org/article/ae2b6adc13ac4043ab6d930d0e7fef42 kostenfrei https://www.cambridge.org/core/product/identifier/S0924933822003571/type/journal_article kostenfrei https://doaj.org/toc/0924-9338 Journal toc kostenfrei https://doaj.org/toc/1778-3585 Journal toc kostenfrei GBV_USEFLAG_A SYSFLAG_A GBV_DOAJ GBV_ILN_20 GBV_ILN_22 GBV_ILN_23 GBV_ILN_24 GBV_ILN_31 GBV_ILN_39 GBV_ILN_40 GBV_ILN_60 GBV_ILN_62 GBV_ILN_63 GBV_ILN_65 GBV_ILN_69 GBV_ILN_73 GBV_ILN_74 GBV_ILN_95 GBV_ILN_105 GBV_ILN_110 GBV_ILN_151 GBV_ILN_161 GBV_ILN_170 GBV_ILN_206 GBV_ILN_213 GBV_ILN_217 GBV_ILN_230 GBV_ILN_285 GBV_ILN_293 GBV_ILN_374 GBV_ILN_602 GBV_ILN_636 GBV_ILN_2004 GBV_ILN_2014 GBV_ILN_2110 GBV_ILN_2336 GBV_ILN_2470 GBV_ILN_4012 GBV_ILN_4037 GBV_ILN_4112 GBV_ILN_4125 GBV_ILN_4126 GBV_ILN_4249 GBV_ILN_4305 GBV_ILN_4306 GBV_ILN_4307 GBV_ILN_4313 GBV_ILN_4322 GBV_ILN_4323 GBV_ILN_4324 GBV_ILN_4325 GBV_ILN_4338 GBV_ILN_4367 GBV_ILN_4700 AR 65 2022 S130-S131
language	English
source	In European Psychiatry 65(2022), Seite S130-S131 volume:65 year:2022 pages:S130-S131
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authorswithroles_txt_mv	B. Fernández-Abascal @@aut@@ P. Suárez-Pinilla @@aut@@ C. Cobo-Corrales @@aut@@ B. Crespo-Facorro @@aut@@ M. Suarez-Pinilla @@aut@@
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Objectives Evaluate the effectiveness of a combined intervention of exercise and psychoeducation in 48 SSD outpatients with metabolic syndrome (MetS), treated with second-generation antipsychotics and also aimed to explore if the effect persisted in a long-term follow-up of 24 months. Methods The intervention included a 12-week aerobic exercise program and a session of lifestyle psychoeducation. Effectiveness was measured in terms a wide range of outcomes involving physical and psychological health, functioning, quality of life, physical activity and changes in motivation to exercise in the context of the self-determination theory. Results The active intervention group showed benefits after Bonferroni correction over clinical global impression, identified motivation to exercise and changes of physical activity pattern. Maintenance of effects after 24 months of follow-up was observed for identified regulation to exercise and also for negative symptoms of psychosis (Table). Table. Effects assigned-group/time-over p≤0.05 p≤0.01. Variables 12weeks 24months Time Groupxtime Groupx timex gender p p p p p HDL (mg/dl) 0.021 Negative Syndrome Scale 0.044* 0.004 BREQ-2- Extrinsic regulation 0.008 0.004** -External 0.026* -Introyected 0.038* -Identified 0.018* 0.015* 0.003 0.002 BREQ-2-Intrinsic regulation 0.005 0.004 Pedometer (steps/day) 0.001 0.006 Conclusions A combined intervention on SSD outpatients with MetS showed effectiveness over several clinical parameters and functioning. Therefore, should be considered an essential part of the integral treatment in mental health services for SSD patients. 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topic_title	RC435-571 Lifestyle intervention on psychotherapy and exercise and their effect on physical and psychological health in outpatients with schizophrenia spectrum disorders. A pragmatic clinical trial non-affective psychosis exercise Quality of Life cardiometabolic risk
topic	misc RC435-571 misc non-affective psychosis, misc exercise misc Quality of Life misc cardiometabolic risk misc Psychiatry
topic_unstemmed	misc RC435-571 misc non-affective psychosis, misc exercise misc Quality of Life misc cardiometabolic risk misc Psychiatry
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title	Lifestyle intervention on psychotherapy and exercise and their effect on physical and psychological health in outpatients with schizophrenia spectrum disorders. A pragmatic clinical trial
ctrlnum	(DE-627)DOAJ094633762 (DE-599)DOAJae2b6adc13ac4043ab6d930d0e7fef42
title_full	Lifestyle intervention on psychotherapy and exercise and their effect on physical and psychological health in outpatients with schizophrenia spectrum disorders. A pragmatic clinical trial
author_sort	B. Fernández-Abascal
journal	European Psychiatry
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author_browse	B. Fernández-Abascal P. Suárez-Pinilla C. Cobo-Corrales B. Crespo-Facorro M. Suarez-Pinilla
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author-letter	B. Fernández-Abascal
doi_str_mv	10.1192/j.eurpsy.2022.357
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title_sort	lifestyle intervention on psychotherapy and exercise and their effect on physical and psychological health in outpatients with schizophrenia spectrum disorders. a pragmatic clinical trial
callnumber	RC435-571
title_auth	Lifestyle intervention on psychotherapy and exercise and their effect on physical and psychological health in outpatients with schizophrenia spectrum disorders. A pragmatic clinical trial
abstract	Introduction Patients with Schizophrenia Spectrum Disorders (SSD) often lead unhealthy lifestyles with higher prevalence of obesity and unfavourable cardiometabolic parameters with less life expectancy and often worse quality of life compared with general population. Objectives Evaluate the effectiveness of a combined intervention of exercise and psychoeducation in 48 SSD outpatients with metabolic syndrome (MetS), treated with second-generation antipsychotics and also aimed to explore if the effect persisted in a long-term follow-up of 24 months. Methods The intervention included a 12-week aerobic exercise program and a session of lifestyle psychoeducation. Effectiveness was measured in terms a wide range of outcomes involving physical and psychological health, functioning, quality of life, physical activity and changes in motivation to exercise in the context of the self-determination theory. Results The active intervention group showed benefits after Bonferroni correction over clinical global impression, identified motivation to exercise and changes of physical activity pattern. Maintenance of effects after 24 months of follow-up was observed for identified regulation to exercise and also for negative symptoms of psychosis (Table). Table. Effects assigned-group/time-over p≤0.05 p≤0.01. Variables 12weeks 24months Time Groupxtime Groupx timex gender p p p p p HDL (mg/dl) 0.021 Negative Syndrome Scale 0.044* 0.004 BREQ-2- Extrinsic regulation 0.008 0.004** -External 0.026* -Introyected 0.038* -Identified 0.018* 0.015* 0.003 0.002 BREQ-2-Intrinsic regulation 0.005 0.004 Pedometer (steps/day) 0.001 0.006 Conclusions A combined intervention on SSD outpatients with MetS showed effectiveness over several clinical parameters and functioning. Therefore, should be considered an essential part of the integral treatment in mental health services for SSD patients. Disclosure No significant relationships.
abstractGer	Introduction Patients with Schizophrenia Spectrum Disorders (SSD) often lead unhealthy lifestyles with higher prevalence of obesity and unfavourable cardiometabolic parameters with less life expectancy and often worse quality of life compared with general population. Objectives Evaluate the effectiveness of a combined intervention of exercise and psychoeducation in 48 SSD outpatients with metabolic syndrome (MetS), treated with second-generation antipsychotics and also aimed to explore if the effect persisted in a long-term follow-up of 24 months. Methods The intervention included a 12-week aerobic exercise program and a session of lifestyle psychoeducation. Effectiveness was measured in terms a wide range of outcomes involving physical and psychological health, functioning, quality of life, physical activity and changes in motivation to exercise in the context of the self-determination theory. Results The active intervention group showed benefits after Bonferroni correction over clinical global impression, identified motivation to exercise and changes of physical activity pattern. Maintenance of effects after 24 months of follow-up was observed for identified regulation to exercise and also for negative symptoms of psychosis (Table). Table. Effects assigned-group/time-over p≤0.05 p≤0.01. Variables 12weeks 24months Time Groupxtime Groupx timex gender p p p p p HDL (mg/dl) 0.021 Negative Syndrome Scale 0.044* 0.004 BREQ-2- Extrinsic regulation 0.008 0.004** -External 0.026* -Introyected 0.038* -Identified 0.018* 0.015* 0.003 0.002 BREQ-2-Intrinsic regulation 0.005 0.004 Pedometer (steps/day) 0.001 0.006 Conclusions A combined intervention on SSD outpatients with MetS showed effectiveness over several clinical parameters and functioning. Therefore, should be considered an essential part of the integral treatment in mental health services for SSD patients. Disclosure No significant relationships.
abstract_unstemmed	Introduction Patients with Schizophrenia Spectrum Disorders (SSD) often lead unhealthy lifestyles with higher prevalence of obesity and unfavourable cardiometabolic parameters with less life expectancy and often worse quality of life compared with general population. Objectives Evaluate the effectiveness of a combined intervention of exercise and psychoeducation in 48 SSD outpatients with metabolic syndrome (MetS), treated with second-generation antipsychotics and also aimed to explore if the effect persisted in a long-term follow-up of 24 months. Methods The intervention included a 12-week aerobic exercise program and a session of lifestyle psychoeducation. Effectiveness was measured in terms a wide range of outcomes involving physical and psychological health, functioning, quality of life, physical activity and changes in motivation to exercise in the context of the self-determination theory. Results The active intervention group showed benefits after Bonferroni correction over clinical global impression, identified motivation to exercise and changes of physical activity pattern. Maintenance of effects after 24 months of follow-up was observed for identified regulation to exercise and also for negative symptoms of psychosis (Table). Table. Effects assigned-group/time-over p≤0.05 p≤0.01. Variables 12weeks 24months Time Groupxtime Groupx timex gender p p p p p HDL (mg/dl) 0.021 Negative Syndrome Scale 0.044* 0.004 BREQ-2- Extrinsic regulation 0.008 0.004** -External 0.026* -Introyected 0.038* -Identified 0.018* 0.015* 0.003 0.002 BREQ-2-Intrinsic regulation 0.005 0.004 Pedometer (steps/day) 0.001 0.006 Conclusions A combined intervention on SSD outpatients with MetS showed effectiveness over several clinical parameters and functioning. Therefore, should be considered an essential part of the integral treatment in mental health services for SSD patients. Disclosure No significant relationships.
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title_short	Lifestyle intervention on psychotherapy and exercise and their effect on physical and psychological health in outpatients with schizophrenia spectrum disorders. A pragmatic clinical trial
url	https://doi.org/10.1192/j.eurpsy.2022.357 https://doaj.org/article/ae2b6adc13ac4043ab6d930d0e7fef42 https://www.cambridge.org/core/product/identifier/S0924933822003571/type/journal_article https://doaj.org/toc/0924-9338 https://doaj.org/toc/1778-3585
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