Bleb Morphology on Anterior-Segment Optical Coherence Tomography after XEN Gel Stent Implantation

We investigated the internal morphology of filtration blebs after XEN gel stent implantation using anterior segment optical coherence tomography (AS-OCT) and identified factors related to intraocular pressure (IOP) postoperatively. Eighteen eyes of 18 patients who had undergone XEN gel stent implant...
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Autor*in:	Seoyoung Wy [verfasserIn] Young In Shin [verfasserIn] Young Kook Kim [verfasserIn] Jin Wook Jeoung [verfasserIn] Ki Ho Park [verfasserIn]

Format:	E-Artikel
Sprache:	Englisch

Erschienen:	2023

Schlagwörter:	XEN gel stent implantation bleb morphology anterior-segment optical coherence tomography

Übergeordnetes Werk:	In: Journal of Clinical Medicine - MDPI AG, 2013, 12(2023), 21, p 6740
Übergeordnetes Werk:	volume:12 ; year:2023 ; number:21, p 6740

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DOI / URN:	10.3390/jcm12216740

Katalog-ID:	DOAJ095457143

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520			\|a We investigated the internal morphology of filtration blebs after XEN gel stent implantation using anterior segment optical coherence tomography (AS-OCT) and identified factors related to intraocular pressure (IOP) postoperatively. Eighteen eyes of 18 patients who had undergone XEN gel stent implantation were analyzed. Blebs were imaged using Visante OCT (Carl Zeiss Meditec AG, Germany) at 6 months and 1 year after surgery and evaluated for quantitative parameters including bleb height, maximum height of internal cavity, maximum bleb wall thickness, and maximum bleb epithelial thickness. Subjects were classified into two groups according to the presence or absence of a definite internal cavity between the conjunctiva and sclera using AS-OCT imaging. Nine eyes (50%) were assigned to the internal cavity group and 9 (50%) to the uniform group. Postoperative IOP was significantly lower in the internal cavity group than in the uniform group both at 6 months and 1 year after surgery (<i<p</i< = 0.024 and <i<p</i< = 0.040). Postoperative IOP showed statistically significant negative correlations with bleb height and the height of the internal cavity (Spearman correlation coefficient r = −0.518, <i<p</i< = 0.028 and r = −0.453, <i<p</i< = 0.034, respectively). AS-OCT facilitates analysis of bleb morphology after XEN gel stent implantation. A larger height of the internal cavity of the bleb appeared to correlate with lower IOP after XEN implantation.
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allfieldsSound	10.3390/jcm12216740 doi (DE-627)DOAJ095457143 (DE-599)DOAJ8262af7dc8f84791a8243b18981d21e4 DE-627 ger DE-627 rakwb eng Seoyoung Wy verfasserin aut Bleb Morphology on Anterior-Segment Optical Coherence Tomography after XEN Gel Stent Implantation 2023 Text txt rdacontent Computermedien c rdamedia Online-Ressource cr rdacarrier We investigated the internal morphology of filtration blebs after XEN gel stent implantation using anterior segment optical coherence tomography (AS-OCT) and identified factors related to intraocular pressure (IOP) postoperatively. Eighteen eyes of 18 patients who had undergone XEN gel stent implantation were analyzed. Blebs were imaged using Visante OCT (Carl Zeiss Meditec AG, Germany) at 6 months and 1 year after surgery and evaluated for quantitative parameters including bleb height, maximum height of internal cavity, maximum bleb wall thickness, and maximum bleb epithelial thickness. Subjects were classified into two groups according to the presence or absence of a definite internal cavity between the conjunctiva and sclera using AS-OCT imaging. Nine eyes (50%) were assigned to the internal cavity group and 9 (50%) to the uniform group. Postoperative IOP was significantly lower in the internal cavity group than in the uniform group both at 6 months and 1 year after surgery (<i<p</i< = 0.024 and <i<p</i< = 0.040). Postoperative IOP showed statistically significant negative correlations with bleb height and the height of the internal cavity (Spearman correlation coefficient r = −0.518, <i<p</i< = 0.028 and r = −0.453, <i<p</i< = 0.034, respectively). AS-OCT facilitates analysis of bleb morphology after XEN gel stent implantation. A larger height of the internal cavity of the bleb appeared to correlate with lower IOP after XEN implantation. XEN gel stent implantation bleb morphology anterior-segment optical coherence tomography Medicine R Young In Shin verfasserin aut Young Kook Kim verfasserin aut Jin Wook Jeoung verfasserin aut Ki Ho Park verfasserin aut In Journal of Clinical Medicine MDPI AG, 2013 12(2023), 21, p 6740 (DE-627)718632478 (DE-600)2662592-1 20770383 nnns volume:12 year:2023 number:21, p 6740 https://doi.org/10.3390/jcm12216740 kostenfrei https://doaj.org/article/8262af7dc8f84791a8243b18981d21e4 kostenfrei https://www.mdpi.com/2077-0383/12/21/6740 kostenfrei https://doaj.org/toc/2077-0383 Journal toc kostenfrei GBV_USEFLAG_A SYSFLAG_A GBV_DOAJ GBV_ILN_20 GBV_ILN_22 GBV_ILN_23 GBV_ILN_24 GBV_ILN_39 GBV_ILN_40 GBV_ILN_60 GBV_ILN_62 GBV_ILN_63 GBV_ILN_65 GBV_ILN_69 GBV_ILN_73 GBV_ILN_74 GBV_ILN_95 GBV_ILN_105 GBV_ILN_110 GBV_ILN_151 GBV_ILN_161 GBV_ILN_170 GBV_ILN_206 GBV_ILN_213 GBV_ILN_230 GBV_ILN_285 GBV_ILN_293 GBV_ILN_602 GBV_ILN_2005 GBV_ILN_2009 GBV_ILN_2014 GBV_ILN_2055 GBV_ILN_2111 GBV_ILN_4012 GBV_ILN_4037 GBV_ILN_4112 GBV_ILN_4125 GBV_ILN_4126 GBV_ILN_4249 GBV_ILN_4305 GBV_ILN_4306 GBV_ILN_4307 GBV_ILN_4313 GBV_ILN_4322 GBV_ILN_4323 GBV_ILN_4324 GBV_ILN_4325 GBV_ILN_4338 GBV_ILN_4367 GBV_ILN_4700 AR 12 2023 21, p 6740
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author	Seoyoung Wy
spellingShingle	Seoyoung Wy misc XEN gel stent implantation misc bleb morphology misc anterior-segment optical coherence tomography misc Medicine misc R Bleb Morphology on Anterior-Segment Optical Coherence Tomography after XEN Gel Stent Implantation
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topic_title	Bleb Morphology on Anterior-Segment Optical Coherence Tomography after XEN Gel Stent Implantation XEN gel stent implantation bleb morphology anterior-segment optical coherence tomography
topic	misc XEN gel stent implantation misc bleb morphology misc anterior-segment optical coherence tomography misc Medicine misc R
topic_unstemmed	misc XEN gel stent implantation misc bleb morphology misc anterior-segment optical coherence tomography misc Medicine misc R
topic_browse	misc XEN gel stent implantation misc bleb morphology misc anterior-segment optical coherence tomography misc Medicine misc R
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title	Bleb Morphology on Anterior-Segment Optical Coherence Tomography after XEN Gel Stent Implantation
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title_full	Bleb Morphology on Anterior-Segment Optical Coherence Tomography after XEN Gel Stent Implantation
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author_browse	Seoyoung Wy Young In Shin Young Kook Kim Jin Wook Jeoung Ki Ho Park
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doi_str_mv	10.3390/jcm12216740
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title_sort	bleb morphology on anterior-segment optical coherence tomography after xen gel stent implantation
title_auth	Bleb Morphology on Anterior-Segment Optical Coherence Tomography after XEN Gel Stent Implantation
abstract	We investigated the internal morphology of filtration blebs after XEN gel stent implantation using anterior segment optical coherence tomography (AS-OCT) and identified factors related to intraocular pressure (IOP) postoperatively. Eighteen eyes of 18 patients who had undergone XEN gel stent implantation were analyzed. Blebs were imaged using Visante OCT (Carl Zeiss Meditec AG, Germany) at 6 months and 1 year after surgery and evaluated for quantitative parameters including bleb height, maximum height of internal cavity, maximum bleb wall thickness, and maximum bleb epithelial thickness. Subjects were classified into two groups according to the presence or absence of a definite internal cavity between the conjunctiva and sclera using AS-OCT imaging. Nine eyes (50%) were assigned to the internal cavity group and 9 (50%) to the uniform group. Postoperative IOP was significantly lower in the internal cavity group than in the uniform group both at 6 months and 1 year after surgery (<i<p</i< = 0.024 and <i<p</i< = 0.040). Postoperative IOP showed statistically significant negative correlations with bleb height and the height of the internal cavity (Spearman correlation coefficient r = −0.518, <i<p</i< = 0.028 and r = −0.453, <i<p</i< = 0.034, respectively). AS-OCT facilitates analysis of bleb morphology after XEN gel stent implantation. A larger height of the internal cavity of the bleb appeared to correlate with lower IOP after XEN implantation.
abstractGer	We investigated the internal morphology of filtration blebs after XEN gel stent implantation using anterior segment optical coherence tomography (AS-OCT) and identified factors related to intraocular pressure (IOP) postoperatively. Eighteen eyes of 18 patients who had undergone XEN gel stent implantation were analyzed. Blebs were imaged using Visante OCT (Carl Zeiss Meditec AG, Germany) at 6 months and 1 year after surgery and evaluated for quantitative parameters including bleb height, maximum height of internal cavity, maximum bleb wall thickness, and maximum bleb epithelial thickness. Subjects were classified into two groups according to the presence or absence of a definite internal cavity between the conjunctiva and sclera using AS-OCT imaging. Nine eyes (50%) were assigned to the internal cavity group and 9 (50%) to the uniform group. Postoperative IOP was significantly lower in the internal cavity group than in the uniform group both at 6 months and 1 year after surgery (<i<p</i< = 0.024 and <i<p</i< = 0.040). Postoperative IOP showed statistically significant negative correlations with bleb height and the height of the internal cavity (Spearman correlation coefficient r = −0.518, <i<p</i< = 0.028 and r = −0.453, <i<p</i< = 0.034, respectively). AS-OCT facilitates analysis of bleb morphology after XEN gel stent implantation. A larger height of the internal cavity of the bleb appeared to correlate with lower IOP after XEN implantation.
abstract_unstemmed	We investigated the internal morphology of filtration blebs after XEN gel stent implantation using anterior segment optical coherence tomography (AS-OCT) and identified factors related to intraocular pressure (IOP) postoperatively. Eighteen eyes of 18 patients who had undergone XEN gel stent implantation were analyzed. Blebs were imaged using Visante OCT (Carl Zeiss Meditec AG, Germany) at 6 months and 1 year after surgery and evaluated for quantitative parameters including bleb height, maximum height of internal cavity, maximum bleb wall thickness, and maximum bleb epithelial thickness. Subjects were classified into two groups according to the presence or absence of a definite internal cavity between the conjunctiva and sclera using AS-OCT imaging. Nine eyes (50%) were assigned to the internal cavity group and 9 (50%) to the uniform group. Postoperative IOP was significantly lower in the internal cavity group than in the uniform group both at 6 months and 1 year after surgery (<i<p</i< = 0.024 and <i<p</i< = 0.040). Postoperative IOP showed statistically significant negative correlations with bleb height and the height of the internal cavity (Spearman correlation coefficient r = −0.518, <i<p</i< = 0.028 and r = −0.453, <i<p</i< = 0.034, respectively). AS-OCT facilitates analysis of bleb morphology after XEN gel stent implantation. A larger height of the internal cavity of the bleb appeared to correlate with lower IOP after XEN implantation.
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title_short	Bleb Morphology on Anterior-Segment Optical Coherence Tomography after XEN Gel Stent Implantation
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up_date	2024-07-03T14:46:33.971Z
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