Functional Aspects of the Obesity Paradox in Patients with Severe Coronavirus Disease-2019: A Retrospective, Multicenter Study
Background Results of studies investigating the association between body mass index (BMI) and mortality in patients with coronavirus disease-2019 (COVID-19) have been conflicting. Methods This multicenter, retrospective observational study, conducted between January 2020 and August 2021, evaluated t...
Ausführliche Beschreibung
Gespeichert in:
| Autor*in: |
Jeongsu Kim [verfasserIn] Jin Ho Jang [verfasserIn] Kipoong Kim [verfasserIn] Sunghoon Park [verfasserIn] Su Hwan Lee [verfasserIn] Onyu Park [verfasserIn] Tae Hwa Kim [verfasserIn] Hye Ju yeo [verfasserIn] Woo Hyun Cho [verfasserIn] |
|---|
| Format: |
E-Artikel |
|---|---|
| Sprache: |
Englisch |
| Erschienen: |
2024 |
|---|
| Schlagwörter: |
|---|
| Übergeordnetes Werk: |
In: Tuberculosis and Respiratory Diseases - The Korean Academy of Tuberculosis and Respiratory Diseases, 2018, 87(2024), 2, Seite 176-184 |
|---|---|
| Übergeordnetes Werk: |
volume:87 ; year:2024 ; number:2 ; pages:176-184 |
| Links: |
Link aufrufen |
|---|
| DOI / URN: |
10.4046/trd.2023.0126 |
|---|
| Katalog-ID: |
DOAJ095820566 |
|---|
| LEADER | 01000naa a22002652 4500 | ||
|---|---|---|---|
| 001 | DOAJ095820566 | ||
| 003 | DE-627 | ||
| 005 | 20240413123641.0 | ||
| 007 | cr uuu---uuuuu | ||
| 008 | 240413s2024 xx |||||o 00| ||eng c | ||
| 024 | 7 | |a 10.4046/trd.2023.0126 |2 doi | |
| 035 | |a (DE-627)DOAJ095820566 | ||
| 035 | |a (DE-599)DOAJ707582ec06c94113aa5fc1a47840e614 | ||
| 040 | |a DE-627 |b ger |c DE-627 |e rakwb | ||
| 041 | |a eng | ||
| 050 | 0 | |a RC705-779 | |
| 100 | 0 | |a Jeongsu Kim |e verfasserin |4 aut | |
| 245 | 1 | 0 | |a Functional Aspects of the Obesity Paradox in Patients with Severe Coronavirus Disease-2019: A Retrospective, Multicenter Study |
| 264 | 1 | |c 2024 | |
| 336 | |a Text |b txt |2 rdacontent | ||
| 337 | |a Computermedien |b c |2 rdamedia | ||
| 338 | |a Online-Ressource |b cr |2 rdacarrier | ||
| 520 | |a Background Results of studies investigating the association between body mass index (BMI) and mortality in patients with coronavirus disease-2019 (COVID-19) have been conflicting. Methods This multicenter, retrospective observational study, conducted between January 2020 and August 2021, evaluated the impact of obesity on outcomes in patients with severe COVID-19 in a Korean national cohort. A total of 1,114 patients were enrolled from 22 tertiary referral hospitals or university-affiliated hospitals, of whom 1,099 were included in the analysis, excluding 15 with unavailable height and weight information. The effect(s) of BMI on patients with severe COVID-19 were analyzed. Results According to the World Health Organization BMI classification, 59 patients were underweight, 541 were normal, 389 were overweight, and 110 were obese. The overall 28-day mortality rate was 15.3%, and there was no significant difference according to BMI. Univariate Cox analysis revealed that BMI was associated with 28-day mortality (hazard ratio, 0.96; p=0.045), but not in the multivariate analysis. Additionally, patients were divided into two groups based on BMI ≥25 kg/m2 and underwent propensity score matching analysis, in which the two groups exhibited no significant difference in mortality at 28 days. The median (interquartile range) clinical frailty scale score at discharge was higher in nonobese patients (3 [3 to 5] vs. 4 [3 to 6], p<0.001). The proportion of frail patients at discharge was significantly higher in the nonobese group (28.1% vs. 46.8%, p<0.001). Conclusion The obesity paradox was not evident in this cohort of patients with severe COVID-19. However, functional outcomes at discharge were better in the obese group. | ||
| 650 | 4 | |a body mass index | |
| 650 | 4 | |a covid-19 | |
| 650 | 4 | |a mortality | |
| 653 | 0 | |a Diseases of the respiratory system | |
| 700 | 0 | |a Jin Ho Jang |e verfasserin |4 aut | |
| 700 | 0 | |a Kipoong Kim |e verfasserin |4 aut | |
| 700 | 0 | |a Sunghoon Park |e verfasserin |4 aut | |
| 700 | 0 | |a Su Hwan Lee |e verfasserin |4 aut | |
| 700 | 0 | |a Onyu Park |e verfasserin |4 aut | |
| 700 | 0 | |a Tae Hwa Kim |e verfasserin |4 aut | |
| 700 | 0 | |a Hye Ju yeo |e verfasserin |4 aut | |
| 700 | 0 | |a Woo Hyun Cho |e verfasserin |4 aut | |
| 773 | 0 | 8 | |i In |t Tuberculosis and Respiratory Diseases |d The Korean Academy of Tuberculosis and Respiratory Diseases, 2018 |g 87(2024), 2, Seite 176-184 |w (DE-627)1760599808 |x 20056184 |7 nnns |
| 773 | 1 | 8 | |g volume:87 |g year:2024 |g number:2 |g pages:176-184 |
| 856 | 4 | 0 | |u https://doi.org/10.4046/trd.2023.0126 |z kostenfrei |
| 856 | 4 | 0 | |u https://doaj.org/article/707582ec06c94113aa5fc1a47840e614 |z kostenfrei |
| 856 | 4 | 0 | |u http://e-trd.org/upload/pdf/trd-2023-0126.pdf |z kostenfrei |
| 856 | 4 | 2 | |u https://doaj.org/toc/1738-3536 |y Journal toc |z kostenfrei |
| 856 | 4 | 2 | |u https://doaj.org/toc/2005-6184 |y Journal toc |z kostenfrei |
| 912 | |a GBV_USEFLAG_A | ||
| 912 | |a SYSFLAG_A | ||
| 912 | |a GBV_DOAJ | ||
| 951 | |a AR | ||
| 952 | |d 87 |j 2024 |e 2 |h 176-184 | ||
| author_variant |
j k jk j h j jhj k k kk s p sp s h l shl o p op t h k thk h j y hjy w h c whc |
|---|---|
| matchkey_str |
article:20056184:2024----::ucinlsetotebstprdxnainsiheeeooaiudsae09r |
| hierarchy_sort_str |
2024 |
| callnumber-subject-code |
RC |
| publishDate |
2024 |
| allfields |
10.4046/trd.2023.0126 doi (DE-627)DOAJ095820566 (DE-599)DOAJ707582ec06c94113aa5fc1a47840e614 DE-627 ger DE-627 rakwb eng RC705-779 Jeongsu Kim verfasserin aut Functional Aspects of the Obesity Paradox in Patients with Severe Coronavirus Disease-2019: A Retrospective, Multicenter Study 2024 Text txt rdacontent Computermedien c rdamedia Online-Ressource cr rdacarrier Background Results of studies investigating the association between body mass index (BMI) and mortality in patients with coronavirus disease-2019 (COVID-19) have been conflicting. Methods This multicenter, retrospective observational study, conducted between January 2020 and August 2021, evaluated the impact of obesity on outcomes in patients with severe COVID-19 in a Korean national cohort. A total of 1,114 patients were enrolled from 22 tertiary referral hospitals or university-affiliated hospitals, of whom 1,099 were included in the analysis, excluding 15 with unavailable height and weight information. The effect(s) of BMI on patients with severe COVID-19 were analyzed. Results According to the World Health Organization BMI classification, 59 patients were underweight, 541 were normal, 389 were overweight, and 110 were obese. The overall 28-day mortality rate was 15.3%, and there was no significant difference according to BMI. Univariate Cox analysis revealed that BMI was associated with 28-day mortality (hazard ratio, 0.96; p=0.045), but not in the multivariate analysis. Additionally, patients were divided into two groups based on BMI ≥25 kg/m2 and underwent propensity score matching analysis, in which the two groups exhibited no significant difference in mortality at 28 days. The median (interquartile range) clinical frailty scale score at discharge was higher in nonobese patients (3 [3 to 5] vs. 4 [3 to 6], p<0.001). The proportion of frail patients at discharge was significantly higher in the nonobese group (28.1% vs. 46.8%, p<0.001). Conclusion The obesity paradox was not evident in this cohort of patients with severe COVID-19. However, functional outcomes at discharge were better in the obese group. body mass index covid-19 mortality Diseases of the respiratory system Jin Ho Jang verfasserin aut Kipoong Kim verfasserin aut Sunghoon Park verfasserin aut Su Hwan Lee verfasserin aut Onyu Park verfasserin aut Tae Hwa Kim verfasserin aut Hye Ju yeo verfasserin aut Woo Hyun Cho verfasserin aut In Tuberculosis and Respiratory Diseases The Korean Academy of Tuberculosis and Respiratory Diseases, 2018 87(2024), 2, Seite 176-184 (DE-627)1760599808 20056184 nnns volume:87 year:2024 number:2 pages:176-184 https://doi.org/10.4046/trd.2023.0126 kostenfrei https://doaj.org/article/707582ec06c94113aa5fc1a47840e614 kostenfrei http://e-trd.org/upload/pdf/trd-2023-0126.pdf kostenfrei https://doaj.org/toc/1738-3536 Journal toc kostenfrei https://doaj.org/toc/2005-6184 Journal toc kostenfrei GBV_USEFLAG_A SYSFLAG_A GBV_DOAJ AR 87 2024 2 176-184 |
| spelling |
10.4046/trd.2023.0126 doi (DE-627)DOAJ095820566 (DE-599)DOAJ707582ec06c94113aa5fc1a47840e614 DE-627 ger DE-627 rakwb eng RC705-779 Jeongsu Kim verfasserin aut Functional Aspects of the Obesity Paradox in Patients with Severe Coronavirus Disease-2019: A Retrospective, Multicenter Study 2024 Text txt rdacontent Computermedien c rdamedia Online-Ressource cr rdacarrier Background Results of studies investigating the association between body mass index (BMI) and mortality in patients with coronavirus disease-2019 (COVID-19) have been conflicting. Methods This multicenter, retrospective observational study, conducted between January 2020 and August 2021, evaluated the impact of obesity on outcomes in patients with severe COVID-19 in a Korean national cohort. A total of 1,114 patients were enrolled from 22 tertiary referral hospitals or university-affiliated hospitals, of whom 1,099 were included in the analysis, excluding 15 with unavailable height and weight information. The effect(s) of BMI on patients with severe COVID-19 were analyzed. Results According to the World Health Organization BMI classification, 59 patients were underweight, 541 were normal, 389 were overweight, and 110 were obese. The overall 28-day mortality rate was 15.3%, and there was no significant difference according to BMI. Univariate Cox analysis revealed that BMI was associated with 28-day mortality (hazard ratio, 0.96; p=0.045), but not in the multivariate analysis. Additionally, patients were divided into two groups based on BMI ≥25 kg/m2 and underwent propensity score matching analysis, in which the two groups exhibited no significant difference in mortality at 28 days. The median (interquartile range) clinical frailty scale score at discharge was higher in nonobese patients (3 [3 to 5] vs. 4 [3 to 6], p<0.001). The proportion of frail patients at discharge was significantly higher in the nonobese group (28.1% vs. 46.8%, p<0.001). Conclusion The obesity paradox was not evident in this cohort of patients with severe COVID-19. However, functional outcomes at discharge were better in the obese group. body mass index covid-19 mortality Diseases of the respiratory system Jin Ho Jang verfasserin aut Kipoong Kim verfasserin aut Sunghoon Park verfasserin aut Su Hwan Lee verfasserin aut Onyu Park verfasserin aut Tae Hwa Kim verfasserin aut Hye Ju yeo verfasserin aut Woo Hyun Cho verfasserin aut In Tuberculosis and Respiratory Diseases The Korean Academy of Tuberculosis and Respiratory Diseases, 2018 87(2024), 2, Seite 176-184 (DE-627)1760599808 20056184 nnns volume:87 year:2024 number:2 pages:176-184 https://doi.org/10.4046/trd.2023.0126 kostenfrei https://doaj.org/article/707582ec06c94113aa5fc1a47840e614 kostenfrei http://e-trd.org/upload/pdf/trd-2023-0126.pdf kostenfrei https://doaj.org/toc/1738-3536 Journal toc kostenfrei https://doaj.org/toc/2005-6184 Journal toc kostenfrei GBV_USEFLAG_A SYSFLAG_A GBV_DOAJ AR 87 2024 2 176-184 |
| allfields_unstemmed |
10.4046/trd.2023.0126 doi (DE-627)DOAJ095820566 (DE-599)DOAJ707582ec06c94113aa5fc1a47840e614 DE-627 ger DE-627 rakwb eng RC705-779 Jeongsu Kim verfasserin aut Functional Aspects of the Obesity Paradox in Patients with Severe Coronavirus Disease-2019: A Retrospective, Multicenter Study 2024 Text txt rdacontent Computermedien c rdamedia Online-Ressource cr rdacarrier Background Results of studies investigating the association between body mass index (BMI) and mortality in patients with coronavirus disease-2019 (COVID-19) have been conflicting. Methods This multicenter, retrospective observational study, conducted between January 2020 and August 2021, evaluated the impact of obesity on outcomes in patients with severe COVID-19 in a Korean national cohort. A total of 1,114 patients were enrolled from 22 tertiary referral hospitals or university-affiliated hospitals, of whom 1,099 were included in the analysis, excluding 15 with unavailable height and weight information. The effect(s) of BMI on patients with severe COVID-19 were analyzed. Results According to the World Health Organization BMI classification, 59 patients were underweight, 541 were normal, 389 were overweight, and 110 were obese. The overall 28-day mortality rate was 15.3%, and there was no significant difference according to BMI. Univariate Cox analysis revealed that BMI was associated with 28-day mortality (hazard ratio, 0.96; p=0.045), but not in the multivariate analysis. Additionally, patients were divided into two groups based on BMI ≥25 kg/m2 and underwent propensity score matching analysis, in which the two groups exhibited no significant difference in mortality at 28 days. The median (interquartile range) clinical frailty scale score at discharge was higher in nonobese patients (3 [3 to 5] vs. 4 [3 to 6], p<0.001). The proportion of frail patients at discharge was significantly higher in the nonobese group (28.1% vs. 46.8%, p<0.001). Conclusion The obesity paradox was not evident in this cohort of patients with severe COVID-19. However, functional outcomes at discharge were better in the obese group. body mass index covid-19 mortality Diseases of the respiratory system Jin Ho Jang verfasserin aut Kipoong Kim verfasserin aut Sunghoon Park verfasserin aut Su Hwan Lee verfasserin aut Onyu Park verfasserin aut Tae Hwa Kim verfasserin aut Hye Ju yeo verfasserin aut Woo Hyun Cho verfasserin aut In Tuberculosis and Respiratory Diseases The Korean Academy of Tuberculosis and Respiratory Diseases, 2018 87(2024), 2, Seite 176-184 (DE-627)1760599808 20056184 nnns volume:87 year:2024 number:2 pages:176-184 https://doi.org/10.4046/trd.2023.0126 kostenfrei https://doaj.org/article/707582ec06c94113aa5fc1a47840e614 kostenfrei http://e-trd.org/upload/pdf/trd-2023-0126.pdf kostenfrei https://doaj.org/toc/1738-3536 Journal toc kostenfrei https://doaj.org/toc/2005-6184 Journal toc kostenfrei GBV_USEFLAG_A SYSFLAG_A GBV_DOAJ AR 87 2024 2 176-184 |
| allfieldsGer |
10.4046/trd.2023.0126 doi (DE-627)DOAJ095820566 (DE-599)DOAJ707582ec06c94113aa5fc1a47840e614 DE-627 ger DE-627 rakwb eng RC705-779 Jeongsu Kim verfasserin aut Functional Aspects of the Obesity Paradox in Patients with Severe Coronavirus Disease-2019: A Retrospective, Multicenter Study 2024 Text txt rdacontent Computermedien c rdamedia Online-Ressource cr rdacarrier Background Results of studies investigating the association between body mass index (BMI) and mortality in patients with coronavirus disease-2019 (COVID-19) have been conflicting. Methods This multicenter, retrospective observational study, conducted between January 2020 and August 2021, evaluated the impact of obesity on outcomes in patients with severe COVID-19 in a Korean national cohort. A total of 1,114 patients were enrolled from 22 tertiary referral hospitals or university-affiliated hospitals, of whom 1,099 were included in the analysis, excluding 15 with unavailable height and weight information. The effect(s) of BMI on patients with severe COVID-19 were analyzed. Results According to the World Health Organization BMI classification, 59 patients were underweight, 541 were normal, 389 were overweight, and 110 were obese. The overall 28-day mortality rate was 15.3%, and there was no significant difference according to BMI. Univariate Cox analysis revealed that BMI was associated with 28-day mortality (hazard ratio, 0.96; p=0.045), but not in the multivariate analysis. Additionally, patients were divided into two groups based on BMI ≥25 kg/m2 and underwent propensity score matching analysis, in which the two groups exhibited no significant difference in mortality at 28 days. The median (interquartile range) clinical frailty scale score at discharge was higher in nonobese patients (3 [3 to 5] vs. 4 [3 to 6], p<0.001). The proportion of frail patients at discharge was significantly higher in the nonobese group (28.1% vs. 46.8%, p<0.001). Conclusion The obesity paradox was not evident in this cohort of patients with severe COVID-19. However, functional outcomes at discharge were better in the obese group. body mass index covid-19 mortality Diseases of the respiratory system Jin Ho Jang verfasserin aut Kipoong Kim verfasserin aut Sunghoon Park verfasserin aut Su Hwan Lee verfasserin aut Onyu Park verfasserin aut Tae Hwa Kim verfasserin aut Hye Ju yeo verfasserin aut Woo Hyun Cho verfasserin aut In Tuberculosis and Respiratory Diseases The Korean Academy of Tuberculosis and Respiratory Diseases, 2018 87(2024), 2, Seite 176-184 (DE-627)1760599808 20056184 nnns volume:87 year:2024 number:2 pages:176-184 https://doi.org/10.4046/trd.2023.0126 kostenfrei https://doaj.org/article/707582ec06c94113aa5fc1a47840e614 kostenfrei http://e-trd.org/upload/pdf/trd-2023-0126.pdf kostenfrei https://doaj.org/toc/1738-3536 Journal toc kostenfrei https://doaj.org/toc/2005-6184 Journal toc kostenfrei GBV_USEFLAG_A SYSFLAG_A GBV_DOAJ AR 87 2024 2 176-184 |
| allfieldsSound |
10.4046/trd.2023.0126 doi (DE-627)DOAJ095820566 (DE-599)DOAJ707582ec06c94113aa5fc1a47840e614 DE-627 ger DE-627 rakwb eng RC705-779 Jeongsu Kim verfasserin aut Functional Aspects of the Obesity Paradox in Patients with Severe Coronavirus Disease-2019: A Retrospective, Multicenter Study 2024 Text txt rdacontent Computermedien c rdamedia Online-Ressource cr rdacarrier Background Results of studies investigating the association between body mass index (BMI) and mortality in patients with coronavirus disease-2019 (COVID-19) have been conflicting. Methods This multicenter, retrospective observational study, conducted between January 2020 and August 2021, evaluated the impact of obesity on outcomes in patients with severe COVID-19 in a Korean national cohort. A total of 1,114 patients were enrolled from 22 tertiary referral hospitals or university-affiliated hospitals, of whom 1,099 were included in the analysis, excluding 15 with unavailable height and weight information. The effect(s) of BMI on patients with severe COVID-19 were analyzed. Results According to the World Health Organization BMI classification, 59 patients were underweight, 541 were normal, 389 were overweight, and 110 were obese. The overall 28-day mortality rate was 15.3%, and there was no significant difference according to BMI. Univariate Cox analysis revealed that BMI was associated with 28-day mortality (hazard ratio, 0.96; p=0.045), but not in the multivariate analysis. Additionally, patients were divided into two groups based on BMI ≥25 kg/m2 and underwent propensity score matching analysis, in which the two groups exhibited no significant difference in mortality at 28 days. The median (interquartile range) clinical frailty scale score at discharge was higher in nonobese patients (3 [3 to 5] vs. 4 [3 to 6], p<0.001). The proportion of frail patients at discharge was significantly higher in the nonobese group (28.1% vs. 46.8%, p<0.001). Conclusion The obesity paradox was not evident in this cohort of patients with severe COVID-19. However, functional outcomes at discharge were better in the obese group. body mass index covid-19 mortality Diseases of the respiratory system Jin Ho Jang verfasserin aut Kipoong Kim verfasserin aut Sunghoon Park verfasserin aut Su Hwan Lee verfasserin aut Onyu Park verfasserin aut Tae Hwa Kim verfasserin aut Hye Ju yeo verfasserin aut Woo Hyun Cho verfasserin aut In Tuberculosis and Respiratory Diseases The Korean Academy of Tuberculosis and Respiratory Diseases, 2018 87(2024), 2, Seite 176-184 (DE-627)1760599808 20056184 nnns volume:87 year:2024 number:2 pages:176-184 https://doi.org/10.4046/trd.2023.0126 kostenfrei https://doaj.org/article/707582ec06c94113aa5fc1a47840e614 kostenfrei http://e-trd.org/upload/pdf/trd-2023-0126.pdf kostenfrei https://doaj.org/toc/1738-3536 Journal toc kostenfrei https://doaj.org/toc/2005-6184 Journal toc kostenfrei GBV_USEFLAG_A SYSFLAG_A GBV_DOAJ AR 87 2024 2 176-184 |
| language |
English |
| source |
In Tuberculosis and Respiratory Diseases 87(2024), 2, Seite 176-184 volume:87 year:2024 number:2 pages:176-184 |
| sourceStr |
In Tuberculosis and Respiratory Diseases 87(2024), 2, Seite 176-184 volume:87 year:2024 number:2 pages:176-184 |
| format_phy_str_mv |
Article |
| institution |
findex.gbv.de |
| topic_facet |
body mass index covid-19 mortality Diseases of the respiratory system |
| isfreeaccess_bool |
true |
| container_title |
Tuberculosis and Respiratory Diseases |
| authorswithroles_txt_mv |
Jeongsu Kim @@aut@@ Jin Ho Jang @@aut@@ Kipoong Kim @@aut@@ Sunghoon Park @@aut@@ Su Hwan Lee @@aut@@ Onyu Park @@aut@@ Tae Hwa Kim @@aut@@ Hye Ju yeo @@aut@@ Woo Hyun Cho @@aut@@ |
| publishDateDaySort_date |
2024-01-01T00:00:00Z |
| hierarchy_top_id |
1760599808 |
| id |
DOAJ095820566 |
| language_de |
englisch |
| fullrecord |
<?xml version="1.0" encoding="UTF-8"?><collection xmlns="http://www.loc.gov/MARC21/slim"><record><leader>01000naa a22002652 4500</leader><controlfield tag="001">DOAJ095820566</controlfield><controlfield tag="003">DE-627</controlfield><controlfield tag="005">20240413123641.0</controlfield><controlfield tag="007">cr uuu---uuuuu</controlfield><controlfield tag="008">240413s2024 xx |||||o 00| ||eng c</controlfield><datafield tag="024" ind1="7" ind2=" "><subfield code="a">10.4046/trd.2023.0126</subfield><subfield code="2">doi</subfield></datafield><datafield tag="035" ind1=" " ind2=" "><subfield code="a">(DE-627)DOAJ095820566</subfield></datafield><datafield tag="035" ind1=" " ind2=" "><subfield code="a">(DE-599)DOAJ707582ec06c94113aa5fc1a47840e614</subfield></datafield><datafield tag="040" ind1=" " ind2=" "><subfield code="a">DE-627</subfield><subfield code="b">ger</subfield><subfield code="c">DE-627</subfield><subfield code="e">rakwb</subfield></datafield><datafield tag="041" ind1=" " ind2=" "><subfield code="a">eng</subfield></datafield><datafield tag="050" ind1=" " ind2="0"><subfield code="a">RC705-779</subfield></datafield><datafield tag="100" ind1="0" ind2=" "><subfield code="a">Jeongsu Kim</subfield><subfield code="e">verfasserin</subfield><subfield code="4">aut</subfield></datafield><datafield tag="245" ind1="1" ind2="0"><subfield code="a">Functional Aspects of the Obesity Paradox in Patients with Severe Coronavirus Disease-2019: A Retrospective, Multicenter Study</subfield></datafield><datafield tag="264" ind1=" " ind2="1"><subfield code="c">2024</subfield></datafield><datafield tag="336" ind1=" " ind2=" "><subfield code="a">Text</subfield><subfield code="b">txt</subfield><subfield code="2">rdacontent</subfield></datafield><datafield tag="337" ind1=" " ind2=" "><subfield code="a">Computermedien</subfield><subfield code="b">c</subfield><subfield code="2">rdamedia</subfield></datafield><datafield tag="338" ind1=" " ind2=" "><subfield code="a">Online-Ressource</subfield><subfield code="b">cr</subfield><subfield code="2">rdacarrier</subfield></datafield><datafield tag="520" ind1=" " ind2=" "><subfield code="a">Background Results of studies investigating the association between body mass index (BMI) and mortality in patients with coronavirus disease-2019 (COVID-19) have been conflicting. Methods This multicenter, retrospective observational study, conducted between January 2020 and August 2021, evaluated the impact of obesity on outcomes in patients with severe COVID-19 in a Korean national cohort. A total of 1,114 patients were enrolled from 22 tertiary referral hospitals or university-affiliated hospitals, of whom 1,099 were included in the analysis, excluding 15 with unavailable height and weight information. The effect(s) of BMI on patients with severe COVID-19 were analyzed. Results According to the World Health Organization BMI classification, 59 patients were underweight, 541 were normal, 389 were overweight, and 110 were obese. The overall 28-day mortality rate was 15.3%, and there was no significant difference according to BMI. Univariate Cox analysis revealed that BMI was associated with 28-day mortality (hazard ratio, 0.96; p=0.045), but not in the multivariate analysis. Additionally, patients were divided into two groups based on BMI ≥25 kg/m2 and underwent propensity score matching analysis, in which the two groups exhibited no significant difference in mortality at 28 days. The median (interquartile range) clinical frailty scale score at discharge was higher in nonobese patients (3 [3 to 5] vs. 4 [3 to 6], p<0.001). The proportion of frail patients at discharge was significantly higher in the nonobese group (28.1% vs. 46.8%, p<0.001). Conclusion The obesity paradox was not evident in this cohort of patients with severe COVID-19. However, functional outcomes at discharge were better in the obese group.</subfield></datafield><datafield tag="650" ind1=" " ind2="4"><subfield code="a">body mass index</subfield></datafield><datafield tag="650" ind1=" " ind2="4"><subfield code="a">covid-19</subfield></datafield><datafield tag="650" ind1=" " ind2="4"><subfield code="a">mortality</subfield></datafield><datafield tag="653" ind1=" " ind2="0"><subfield code="a">Diseases of the respiratory system</subfield></datafield><datafield tag="700" ind1="0" ind2=" "><subfield code="a">Jin Ho Jang</subfield><subfield code="e">verfasserin</subfield><subfield code="4">aut</subfield></datafield><datafield tag="700" ind1="0" ind2=" "><subfield code="a">Kipoong Kim</subfield><subfield code="e">verfasserin</subfield><subfield code="4">aut</subfield></datafield><datafield tag="700" ind1="0" ind2=" "><subfield code="a">Sunghoon Park</subfield><subfield code="e">verfasserin</subfield><subfield code="4">aut</subfield></datafield><datafield tag="700" ind1="0" ind2=" "><subfield code="a">Su Hwan Lee</subfield><subfield code="e">verfasserin</subfield><subfield code="4">aut</subfield></datafield><datafield tag="700" ind1="0" ind2=" "><subfield code="a">Onyu Park</subfield><subfield code="e">verfasserin</subfield><subfield code="4">aut</subfield></datafield><datafield tag="700" ind1="0" ind2=" "><subfield code="a">Tae Hwa Kim</subfield><subfield code="e">verfasserin</subfield><subfield code="4">aut</subfield></datafield><datafield tag="700" ind1="0" ind2=" "><subfield code="a">Hye Ju yeo</subfield><subfield code="e">verfasserin</subfield><subfield code="4">aut</subfield></datafield><datafield tag="700" ind1="0" ind2=" "><subfield code="a">Woo Hyun Cho</subfield><subfield code="e">verfasserin</subfield><subfield code="4">aut</subfield></datafield><datafield tag="773" ind1="0" ind2="8"><subfield code="i">In</subfield><subfield code="t">Tuberculosis and Respiratory Diseases</subfield><subfield code="d">The Korean Academy of Tuberculosis and Respiratory Diseases, 2018</subfield><subfield code="g">87(2024), 2, Seite 176-184</subfield><subfield code="w">(DE-627)1760599808</subfield><subfield code="x">20056184</subfield><subfield code="7">nnns</subfield></datafield><datafield tag="773" ind1="1" ind2="8"><subfield code="g">volume:87</subfield><subfield code="g">year:2024</subfield><subfield code="g">number:2</subfield><subfield code="g">pages:176-184</subfield></datafield><datafield tag="856" ind1="4" ind2="0"><subfield code="u">https://doi.org/10.4046/trd.2023.0126</subfield><subfield code="z">kostenfrei</subfield></datafield><datafield tag="856" ind1="4" ind2="0"><subfield code="u">https://doaj.org/article/707582ec06c94113aa5fc1a47840e614</subfield><subfield code="z">kostenfrei</subfield></datafield><datafield tag="856" ind1="4" ind2="0"><subfield code="u">http://e-trd.org/upload/pdf/trd-2023-0126.pdf</subfield><subfield code="z">kostenfrei</subfield></datafield><datafield tag="856" ind1="4" ind2="2"><subfield code="u">https://doaj.org/toc/1738-3536</subfield><subfield code="y">Journal toc</subfield><subfield code="z">kostenfrei</subfield></datafield><datafield tag="856" ind1="4" ind2="2"><subfield code="u">https://doaj.org/toc/2005-6184</subfield><subfield code="y">Journal toc</subfield><subfield code="z">kostenfrei</subfield></datafield><datafield tag="912" ind1=" " ind2=" "><subfield code="a">GBV_USEFLAG_A</subfield></datafield><datafield tag="912" ind1=" " ind2=" "><subfield code="a">SYSFLAG_A</subfield></datafield><datafield tag="912" ind1=" " ind2=" "><subfield code="a">GBV_DOAJ</subfield></datafield><datafield tag="951" ind1=" " ind2=" "><subfield code="a">AR</subfield></datafield><datafield tag="952" ind1=" " ind2=" "><subfield code="d">87</subfield><subfield code="j">2024</subfield><subfield code="e">2</subfield><subfield code="h">176-184</subfield></datafield></record></collection>
|
| callnumber-first |
R - Medicine |
| author |
Jeongsu Kim |
| spellingShingle |
Jeongsu Kim misc RC705-779 misc body mass index misc covid-19 misc mortality misc Diseases of the respiratory system Functional Aspects of the Obesity Paradox in Patients with Severe Coronavirus Disease-2019: A Retrospective, Multicenter Study |
| authorStr |
Jeongsu Kim |
| ppnlink_with_tag_str_mv |
@@773@@(DE-627)1760599808 |
| format |
electronic Article |
| delete_txt_mv |
keep |
| author_role |
aut aut aut aut aut aut aut aut aut |
| collection |
DOAJ |
| remote_str |
true |
| callnumber-label |
RC705-779 |
| illustrated |
Not Illustrated |
| issn |
20056184 |
| topic_title |
RC705-779 Functional Aspects of the Obesity Paradox in Patients with Severe Coronavirus Disease-2019: A Retrospective, Multicenter Study body mass index covid-19 mortality |
| topic |
misc RC705-779 misc body mass index misc covid-19 misc mortality misc Diseases of the respiratory system |
| topic_unstemmed |
misc RC705-779 misc body mass index misc covid-19 misc mortality misc Diseases of the respiratory system |
| topic_browse |
misc RC705-779 misc body mass index misc covid-19 misc mortality misc Diseases of the respiratory system |
| format_facet |
Elektronische Aufsätze Aufsätze Elektronische Ressource |
| format_main_str_mv |
Text Zeitschrift/Artikel |
| carriertype_str_mv |
cr |
| hierarchy_parent_title |
Tuberculosis and Respiratory Diseases |
| hierarchy_parent_id |
1760599808 |
| hierarchy_top_title |
Tuberculosis and Respiratory Diseases |
| isfreeaccess_txt |
true |
| familylinks_str_mv |
(DE-627)1760599808 |
| title |
Functional Aspects of the Obesity Paradox in Patients with Severe Coronavirus Disease-2019: A Retrospective, Multicenter Study |
| ctrlnum |
(DE-627)DOAJ095820566 (DE-599)DOAJ707582ec06c94113aa5fc1a47840e614 |
| title_full |
Functional Aspects of the Obesity Paradox in Patients with Severe Coronavirus Disease-2019: A Retrospective, Multicenter Study |
| author_sort |
Jeongsu Kim |
| journal |
Tuberculosis and Respiratory Diseases |
| journalStr |
Tuberculosis and Respiratory Diseases |
| callnumber-first-code |
R |
| lang_code |
eng |
| isOA_bool |
true |
| recordtype |
marc |
| publishDateSort |
2024 |
| contenttype_str_mv |
txt |
| container_start_page |
176 |
| author_browse |
Jeongsu Kim Jin Ho Jang Kipoong Kim Sunghoon Park Su Hwan Lee Onyu Park Tae Hwa Kim Hye Ju yeo Woo Hyun Cho |
| container_volume |
87 |
| class |
RC705-779 |
| format_se |
Elektronische Aufsätze |
| author-letter |
Jeongsu Kim |
| doi_str_mv |
10.4046/trd.2023.0126 |
| author2-role |
verfasserin |
| title_sort |
functional aspects of the obesity paradox in patients with severe coronavirus disease-2019: a retrospective, multicenter study |
| callnumber |
RC705-779 |
| title_auth |
Functional Aspects of the Obesity Paradox in Patients with Severe Coronavirus Disease-2019: A Retrospective, Multicenter Study |
| abstract |
Background Results of studies investigating the association between body mass index (BMI) and mortality in patients with coronavirus disease-2019 (COVID-19) have been conflicting. Methods This multicenter, retrospective observational study, conducted between January 2020 and August 2021, evaluated the impact of obesity on outcomes in patients with severe COVID-19 in a Korean national cohort. A total of 1,114 patients were enrolled from 22 tertiary referral hospitals or university-affiliated hospitals, of whom 1,099 were included in the analysis, excluding 15 with unavailable height and weight information. The effect(s) of BMI on patients with severe COVID-19 were analyzed. Results According to the World Health Organization BMI classification, 59 patients were underweight, 541 were normal, 389 were overweight, and 110 were obese. The overall 28-day mortality rate was 15.3%, and there was no significant difference according to BMI. Univariate Cox analysis revealed that BMI was associated with 28-day mortality (hazard ratio, 0.96; p=0.045), but not in the multivariate analysis. Additionally, patients were divided into two groups based on BMI ≥25 kg/m2 and underwent propensity score matching analysis, in which the two groups exhibited no significant difference in mortality at 28 days. The median (interquartile range) clinical frailty scale score at discharge was higher in nonobese patients (3 [3 to 5] vs. 4 [3 to 6], p<0.001). The proportion of frail patients at discharge was significantly higher in the nonobese group (28.1% vs. 46.8%, p<0.001). Conclusion The obesity paradox was not evident in this cohort of patients with severe COVID-19. However, functional outcomes at discharge were better in the obese group. |
| abstractGer |
Background Results of studies investigating the association between body mass index (BMI) and mortality in patients with coronavirus disease-2019 (COVID-19) have been conflicting. Methods This multicenter, retrospective observational study, conducted between January 2020 and August 2021, evaluated the impact of obesity on outcomes in patients with severe COVID-19 in a Korean national cohort. A total of 1,114 patients were enrolled from 22 tertiary referral hospitals or university-affiliated hospitals, of whom 1,099 were included in the analysis, excluding 15 with unavailable height and weight information. The effect(s) of BMI on patients with severe COVID-19 were analyzed. Results According to the World Health Organization BMI classification, 59 patients were underweight, 541 were normal, 389 were overweight, and 110 were obese. The overall 28-day mortality rate was 15.3%, and there was no significant difference according to BMI. Univariate Cox analysis revealed that BMI was associated with 28-day mortality (hazard ratio, 0.96; p=0.045), but not in the multivariate analysis. Additionally, patients were divided into two groups based on BMI ≥25 kg/m2 and underwent propensity score matching analysis, in which the two groups exhibited no significant difference in mortality at 28 days. The median (interquartile range) clinical frailty scale score at discharge was higher in nonobese patients (3 [3 to 5] vs. 4 [3 to 6], p<0.001). The proportion of frail patients at discharge was significantly higher in the nonobese group (28.1% vs. 46.8%, p<0.001). Conclusion The obesity paradox was not evident in this cohort of patients with severe COVID-19. However, functional outcomes at discharge were better in the obese group. |
| abstract_unstemmed |
Background Results of studies investigating the association between body mass index (BMI) and mortality in patients with coronavirus disease-2019 (COVID-19) have been conflicting. Methods This multicenter, retrospective observational study, conducted between January 2020 and August 2021, evaluated the impact of obesity on outcomes in patients with severe COVID-19 in a Korean national cohort. A total of 1,114 patients were enrolled from 22 tertiary referral hospitals or university-affiliated hospitals, of whom 1,099 were included in the analysis, excluding 15 with unavailable height and weight information. The effect(s) of BMI on patients with severe COVID-19 were analyzed. Results According to the World Health Organization BMI classification, 59 patients were underweight, 541 were normal, 389 were overweight, and 110 were obese. The overall 28-day mortality rate was 15.3%, and there was no significant difference according to BMI. Univariate Cox analysis revealed that BMI was associated with 28-day mortality (hazard ratio, 0.96; p=0.045), but not in the multivariate analysis. Additionally, patients were divided into two groups based on BMI ≥25 kg/m2 and underwent propensity score matching analysis, in which the two groups exhibited no significant difference in mortality at 28 days. The median (interquartile range) clinical frailty scale score at discharge was higher in nonobese patients (3 [3 to 5] vs. 4 [3 to 6], p<0.001). The proportion of frail patients at discharge was significantly higher in the nonobese group (28.1% vs. 46.8%, p<0.001). Conclusion The obesity paradox was not evident in this cohort of patients with severe COVID-19. However, functional outcomes at discharge were better in the obese group. |
| collection_details |
GBV_USEFLAG_A SYSFLAG_A GBV_DOAJ |
| container_issue |
2 |
| title_short |
Functional Aspects of the Obesity Paradox in Patients with Severe Coronavirus Disease-2019: A Retrospective, Multicenter Study |
| url |
https://doi.org/10.4046/trd.2023.0126 https://doaj.org/article/707582ec06c94113aa5fc1a47840e614 http://e-trd.org/upload/pdf/trd-2023-0126.pdf https://doaj.org/toc/1738-3536 https://doaj.org/toc/2005-6184 |
| remote_bool |
true |
| author2 |
Jin Ho Jang Kipoong Kim Sunghoon Park Su Hwan Lee Onyu Park Tae Hwa Kim Hye Ju yeo Woo Hyun Cho |
| author2Str |
Jin Ho Jang Kipoong Kim Sunghoon Park Su Hwan Lee Onyu Park Tae Hwa Kim Hye Ju yeo Woo Hyun Cho |
| ppnlink |
1760599808 |
| callnumber-subject |
RC - Internal Medicine |
| mediatype_str_mv |
c |
| isOA_txt |
true |
| hochschulschrift_bool |
false |
| doi_str |
10.4046/trd.2023.0126 |
| callnumber-a |
RC705-779 |
| up_date |
2024-07-03T16:47:52.974Z |
| _version_ |
1803577220635033600 |
| fullrecord_marcxml |
<?xml version="1.0" encoding="UTF-8"?><collection xmlns="http://www.loc.gov/MARC21/slim"><record><leader>01000naa a22002652 4500</leader><controlfield tag="001">DOAJ095820566</controlfield><controlfield tag="003">DE-627</controlfield><controlfield tag="005">20240413123641.0</controlfield><controlfield tag="007">cr uuu---uuuuu</controlfield><controlfield tag="008">240413s2024 xx |||||o 00| ||eng c</controlfield><datafield tag="024" ind1="7" ind2=" "><subfield code="a">10.4046/trd.2023.0126</subfield><subfield code="2">doi</subfield></datafield><datafield tag="035" ind1=" " ind2=" "><subfield code="a">(DE-627)DOAJ095820566</subfield></datafield><datafield tag="035" ind1=" " ind2=" "><subfield code="a">(DE-599)DOAJ707582ec06c94113aa5fc1a47840e614</subfield></datafield><datafield tag="040" ind1=" " ind2=" "><subfield code="a">DE-627</subfield><subfield code="b">ger</subfield><subfield code="c">DE-627</subfield><subfield code="e">rakwb</subfield></datafield><datafield tag="041" ind1=" " ind2=" "><subfield code="a">eng</subfield></datafield><datafield tag="050" ind1=" " ind2="0"><subfield code="a">RC705-779</subfield></datafield><datafield tag="100" ind1="0" ind2=" "><subfield code="a">Jeongsu Kim</subfield><subfield code="e">verfasserin</subfield><subfield code="4">aut</subfield></datafield><datafield tag="245" ind1="1" ind2="0"><subfield code="a">Functional Aspects of the Obesity Paradox in Patients with Severe Coronavirus Disease-2019: A Retrospective, Multicenter Study</subfield></datafield><datafield tag="264" ind1=" " ind2="1"><subfield code="c">2024</subfield></datafield><datafield tag="336" ind1=" " ind2=" "><subfield code="a">Text</subfield><subfield code="b">txt</subfield><subfield code="2">rdacontent</subfield></datafield><datafield tag="337" ind1=" " ind2=" "><subfield code="a">Computermedien</subfield><subfield code="b">c</subfield><subfield code="2">rdamedia</subfield></datafield><datafield tag="338" ind1=" " ind2=" "><subfield code="a">Online-Ressource</subfield><subfield code="b">cr</subfield><subfield code="2">rdacarrier</subfield></datafield><datafield tag="520" ind1=" " ind2=" "><subfield code="a">Background Results of studies investigating the association between body mass index (BMI) and mortality in patients with coronavirus disease-2019 (COVID-19) have been conflicting. Methods This multicenter, retrospective observational study, conducted between January 2020 and August 2021, evaluated the impact of obesity on outcomes in patients with severe COVID-19 in a Korean national cohort. A total of 1,114 patients were enrolled from 22 tertiary referral hospitals or university-affiliated hospitals, of whom 1,099 were included in the analysis, excluding 15 with unavailable height and weight information. The effect(s) of BMI on patients with severe COVID-19 were analyzed. Results According to the World Health Organization BMI classification, 59 patients were underweight, 541 were normal, 389 were overweight, and 110 were obese. The overall 28-day mortality rate was 15.3%, and there was no significant difference according to BMI. Univariate Cox analysis revealed that BMI was associated with 28-day mortality (hazard ratio, 0.96; p=0.045), but not in the multivariate analysis. Additionally, patients were divided into two groups based on BMI ≥25 kg/m2 and underwent propensity score matching analysis, in which the two groups exhibited no significant difference in mortality at 28 days. The median (interquartile range) clinical frailty scale score at discharge was higher in nonobese patients (3 [3 to 5] vs. 4 [3 to 6], p<0.001). The proportion of frail patients at discharge was significantly higher in the nonobese group (28.1% vs. 46.8%, p<0.001). Conclusion The obesity paradox was not evident in this cohort of patients with severe COVID-19. However, functional outcomes at discharge were better in the obese group.</subfield></datafield><datafield tag="650" ind1=" " ind2="4"><subfield code="a">body mass index</subfield></datafield><datafield tag="650" ind1=" " ind2="4"><subfield code="a">covid-19</subfield></datafield><datafield tag="650" ind1=" " ind2="4"><subfield code="a">mortality</subfield></datafield><datafield tag="653" ind1=" " ind2="0"><subfield code="a">Diseases of the respiratory system</subfield></datafield><datafield tag="700" ind1="0" ind2=" "><subfield code="a">Jin Ho Jang</subfield><subfield code="e">verfasserin</subfield><subfield code="4">aut</subfield></datafield><datafield tag="700" ind1="0" ind2=" "><subfield code="a">Kipoong Kim</subfield><subfield code="e">verfasserin</subfield><subfield code="4">aut</subfield></datafield><datafield tag="700" ind1="0" ind2=" "><subfield code="a">Sunghoon Park</subfield><subfield code="e">verfasserin</subfield><subfield code="4">aut</subfield></datafield><datafield tag="700" ind1="0" ind2=" "><subfield code="a">Su Hwan Lee</subfield><subfield code="e">verfasserin</subfield><subfield code="4">aut</subfield></datafield><datafield tag="700" ind1="0" ind2=" "><subfield code="a">Onyu Park</subfield><subfield code="e">verfasserin</subfield><subfield code="4">aut</subfield></datafield><datafield tag="700" ind1="0" ind2=" "><subfield code="a">Tae Hwa Kim</subfield><subfield code="e">verfasserin</subfield><subfield code="4">aut</subfield></datafield><datafield tag="700" ind1="0" ind2=" "><subfield code="a">Hye Ju yeo</subfield><subfield code="e">verfasserin</subfield><subfield code="4">aut</subfield></datafield><datafield tag="700" ind1="0" ind2=" "><subfield code="a">Woo Hyun Cho</subfield><subfield code="e">verfasserin</subfield><subfield code="4">aut</subfield></datafield><datafield tag="773" ind1="0" ind2="8"><subfield code="i">In</subfield><subfield code="t">Tuberculosis and Respiratory Diseases</subfield><subfield code="d">The Korean Academy of Tuberculosis and Respiratory Diseases, 2018</subfield><subfield code="g">87(2024), 2, Seite 176-184</subfield><subfield code="w">(DE-627)1760599808</subfield><subfield code="x">20056184</subfield><subfield code="7">nnns</subfield></datafield><datafield tag="773" ind1="1" ind2="8"><subfield code="g">volume:87</subfield><subfield code="g">year:2024</subfield><subfield code="g">number:2</subfield><subfield code="g">pages:176-184</subfield></datafield><datafield tag="856" ind1="4" ind2="0"><subfield code="u">https://doi.org/10.4046/trd.2023.0126</subfield><subfield code="z">kostenfrei</subfield></datafield><datafield tag="856" ind1="4" ind2="0"><subfield code="u">https://doaj.org/article/707582ec06c94113aa5fc1a47840e614</subfield><subfield code="z">kostenfrei</subfield></datafield><datafield tag="856" ind1="4" ind2="0"><subfield code="u">http://e-trd.org/upload/pdf/trd-2023-0126.pdf</subfield><subfield code="z">kostenfrei</subfield></datafield><datafield tag="856" ind1="4" ind2="2"><subfield code="u">https://doaj.org/toc/1738-3536</subfield><subfield code="y">Journal toc</subfield><subfield code="z">kostenfrei</subfield></datafield><datafield tag="856" ind1="4" ind2="2"><subfield code="u">https://doaj.org/toc/2005-6184</subfield><subfield code="y">Journal toc</subfield><subfield code="z">kostenfrei</subfield></datafield><datafield tag="912" ind1=" " ind2=" "><subfield code="a">GBV_USEFLAG_A</subfield></datafield><datafield tag="912" ind1=" " ind2=" "><subfield code="a">SYSFLAG_A</subfield></datafield><datafield tag="912" ind1=" " ind2=" "><subfield code="a">GBV_DOAJ</subfield></datafield><datafield tag="951" ind1=" " ind2=" "><subfield code="a">AR</subfield></datafield><datafield tag="952" ind1=" " ind2=" "><subfield code="d">87</subfield><subfield code="j">2024</subfield><subfield code="e">2</subfield><subfield code="h">176-184</subfield></datafield></record></collection>
|
| score |
7.4014397 |