Cross‐sectional and longitudinal association between atrial fibrillation and sarcopenia: Findings from the Korean frailty and aging cohort study

Abstract Background Sarcopenia is commonly observed in patients with cardiovascular diseases. However, studies on the association between sarcopenia and atrial fibrillation and their causal relationships are limited. We performed cross‐sectional and longitudinal analyses to investigate the association between sarcopenia and atrial fibrillation among community‐dwelling older adults. Methods A total of 2225 participants from the Korean Frailty and Aging Cohort Study (KFACS) from 2016 to 2017 were included in this cross‐sectional analysis. Sarcopenia was defined according to the Asian Working Group for Sarcopenia 2019 consensus. Atrial fibrillation was diagnosed on the basis of electrocardiographic findings. We investigated whether atrial fibrillation increased the risk of incident sarcopenia 2 years later and whether sarcopenia, in turn, increased the 2‐year risk of developing atrial fibrillation using KFACS data from 2018 to 2019. Results Of the 2225 participants (54.2% women; mean age 76.0 ± 3.9 years), 509 (22.9%) had sarcopenia at baseline. In the cross‐sectional analysis, sarcopenia was associated with atrial fibrillation after multivariate adjustment [odd ratio (OR), 2.127; 95% confidence interval (CI), 1.240–3.648; P = 0.006]. Among the sarcopenia components, low physical performance was associated with atrial fibrillation (OR, 1.872; 95% CI, 1.123–3.120; P = 0.016). During the 2‐year follow‐up period, atrial fibrillation was not associated with new‐onset of sarcopenia (OR, 1.483; 95% CI, 0.597–3.685; P = 0.396), and sarcopenia also did not significantly increase the risk of incident atrial fibrillation (OR, 1.120; 95% CI, 0.384–3.264; P = 0.836). Conclusions Although we found a significant association between sarcopenia and atrial fibrillation in a cross‐sectional analysis, we could not establish a causal relationship between the two based on 2 years of follow‐up. Further research with long‐term follow‐up is required to identify causal relationship between atrial fibrillation and sarcopenia. Ausführliche Beschreibung

Gespeichert in:

Autor*in:	Ga Yang Shim [verfasserIn] Miji Kim [verfasserIn] Chang Won Won [verfasserIn]

Format:	E-Artikel
Sprache:	Englisch

Erschienen:	2024

Schlagwörter:	Atrial fibrillation Longitudinal analysis Older adults Sarcopenia

Übergeordnetes Werk:	In: Journal of Cachexia, Sarcopenia and Muscle - Wiley, 2016, 15(2024), 1, Seite 434-441
Übergeordnetes Werk:	volume:15 ; year:2024 ; number:1 ; pages:434-441

Links:	Link aufrufen Link aufrufen Link aufrufen Journal toc Journal toc

DOI / URN:	10.1002/jcsm.13401

Katalog-ID:	DOAJ095985301

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520			\|a Abstract Background Sarcopenia is commonly observed in patients with cardiovascular diseases. However, studies on the association between sarcopenia and atrial fibrillation and their causal relationships are limited. We performed cross‐sectional and longitudinal analyses to investigate the association between sarcopenia and atrial fibrillation among community‐dwelling older adults. Methods A total of 2225 participants from the Korean Frailty and Aging Cohort Study (KFACS) from 2016 to 2017 were included in this cross‐sectional analysis. Sarcopenia was defined according to the Asian Working Group for Sarcopenia 2019 consensus. Atrial fibrillation was diagnosed on the basis of electrocardiographic findings. We investigated whether atrial fibrillation increased the risk of incident sarcopenia 2 years later and whether sarcopenia, in turn, increased the 2‐year risk of developing atrial fibrillation using KFACS data from 2018 to 2019. Results Of the 2225 participants (54.2% women; mean age 76.0 ± 3.9 years), 509 (22.9%) had sarcopenia at baseline. In the cross‐sectional analysis, sarcopenia was associated with atrial fibrillation after multivariate adjustment [odd ratio (OR), 2.127; 95% confidence interval (CI), 1.240–3.648; P = 0.006]. Among the sarcopenia components, low physical performance was associated with atrial fibrillation (OR, 1.872; 95% CI, 1.123–3.120; P = 0.016). During the 2‐year follow‐up period, atrial fibrillation was not associated with new‐onset of sarcopenia (OR, 1.483; 95% CI, 0.597–3.685; P = 0.396), and sarcopenia also did not significantly increase the risk of incident atrial fibrillation (OR, 1.120; 95% CI, 0.384–3.264; P = 0.836). Conclusions Although we found a significant association between sarcopenia and atrial fibrillation in a cross‐sectional analysis, we could not establish a causal relationship between the two based on 2 years of follow‐up. Further research with long‐term follow‐up is required to identify causal relationship between atrial fibrillation and sarcopenia.
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allfields	10.1002/jcsm.13401 doi (DE-627)DOAJ095985301 (DE-599)DOAJbf50e2209dd4425cb93889dd11b0c44a DE-627 ger DE-627 rakwb eng RC925-935 QM1-695 Ga Yang Shim verfasserin aut Cross‐sectional and longitudinal association between atrial fibrillation and sarcopenia: Findings from the Korean frailty and aging cohort study 2024 Text txt rdacontent Computermedien c rdamedia Online-Ressource cr rdacarrier Abstract Background Sarcopenia is commonly observed in patients with cardiovascular diseases. However, studies on the association between sarcopenia and atrial fibrillation and their causal relationships are limited. We performed cross‐sectional and longitudinal analyses to investigate the association between sarcopenia and atrial fibrillation among community‐dwelling older adults. Methods A total of 2225 participants from the Korean Frailty and Aging Cohort Study (KFACS) from 2016 to 2017 were included in this cross‐sectional analysis. Sarcopenia was defined according to the Asian Working Group for Sarcopenia 2019 consensus. Atrial fibrillation was diagnosed on the basis of electrocardiographic findings. We investigated whether atrial fibrillation increased the risk of incident sarcopenia 2 years later and whether sarcopenia, in turn, increased the 2‐year risk of developing atrial fibrillation using KFACS data from 2018 to 2019. Results Of the 2225 participants (54.2% women; mean age 76.0 ± 3.9 years), 509 (22.9%) had sarcopenia at baseline. In the cross‐sectional analysis, sarcopenia was associated with atrial fibrillation after multivariate adjustment [odd ratio (OR), 2.127; 95% confidence interval (CI), 1.240–3.648; P = 0.006]. Among the sarcopenia components, low physical performance was associated with atrial fibrillation (OR, 1.872; 95% CI, 1.123–3.120; P = 0.016). During the 2‐year follow‐up period, atrial fibrillation was not associated with new‐onset of sarcopenia (OR, 1.483; 95% CI, 0.597–3.685; P = 0.396), and sarcopenia also did not significantly increase the risk of incident atrial fibrillation (OR, 1.120; 95% CI, 0.384–3.264; P = 0.836). Conclusions Although we found a significant association between sarcopenia and atrial fibrillation in a cross‐sectional analysis, we could not establish a causal relationship between the two based on 2 years of follow‐up. Further research with long‐term follow‐up is required to identify causal relationship between atrial fibrillation and sarcopenia. Atrial fibrillation Longitudinal analysis Older adults Sarcopenia Diseases of the musculoskeletal system Human anatomy Miji Kim verfasserin aut Chang Won Won verfasserin aut In Journal of Cachexia, Sarcopenia and Muscle Wiley, 2016 15(2024), 1, Seite 434-441 (DE-627)642886121 (DE-600)2586864-0 21906009 nnns volume:15 year:2024 number:1 pages:434-441 https://doi.org/10.1002/jcsm.13401 kostenfrei https://doaj.org/article/bf50e2209dd4425cb93889dd11b0c44a kostenfrei https://doi.org/10.1002/jcsm.13401 kostenfrei https://doaj.org/toc/2190-5991 Journal toc kostenfrei https://doaj.org/toc/2190-6009 Journal toc kostenfrei GBV_USEFLAG_A SYSFLAG_A GBV_DOAJ GBV_ILN_20 GBV_ILN_22 GBV_ILN_23 GBV_ILN_24 GBV_ILN_31 GBV_ILN_39 GBV_ILN_40 GBV_ILN_60 GBV_ILN_62 GBV_ILN_63 GBV_ILN_65 GBV_ILN_69 GBV_ILN_73 GBV_ILN_74 GBV_ILN_95 GBV_ILN_105 GBV_ILN_110 GBV_ILN_151 GBV_ILN_161 GBV_ILN_170 GBV_ILN_171 GBV_ILN_206 GBV_ILN_213 GBV_ILN_224 GBV_ILN_230 GBV_ILN_285 GBV_ILN_293 GBV_ILN_602 GBV_ILN_636 GBV_ILN_2004 GBV_ILN_2005 GBV_ILN_2006 GBV_ILN_2007 GBV_ILN_2010 GBV_ILN_2011 GBV_ILN_2014 GBV_ILN_2026 GBV_ILN_2027 GBV_ILN_2034 GBV_ILN_2037 GBV_ILN_2038 GBV_ILN_2044 GBV_ILN_2048 GBV_ILN_2049 GBV_ILN_2050 GBV_ILN_2055 GBV_ILN_2056 GBV_ILN_2057 GBV_ILN_2059 GBV_ILN_2061 GBV_ILN_2064 GBV_ILN_2068 GBV_ILN_2088 GBV_ILN_2106 GBV_ILN_2108 GBV_ILN_2110 GBV_ILN_2111 GBV_ILN_2118 GBV_ILN_2122 GBV_ILN_2143 GBV_ILN_2144 GBV_ILN_2147 GBV_ILN_2148 GBV_ILN_2152 GBV_ILN_2153 GBV_ILN_2232 GBV_ILN_2470 GBV_ILN_2507 GBV_ILN_2522 GBV_ILN_4012 GBV_ILN_4035 GBV_ILN_4037 GBV_ILN_4046 GBV_ILN_4112 GBV_ILN_4125 GBV_ILN_4126 GBV_ILN_4242 GBV_ILN_4249 GBV_ILN_4251 GBV_ILN_4305 GBV_ILN_4306 GBV_ILN_4307 GBV_ILN_4313 GBV_ILN_4322 GBV_ILN_4323 GBV_ILN_4324 GBV_ILN_4325 GBV_ILN_4326 GBV_ILN_4333 GBV_ILN_4334 GBV_ILN_4335 GBV_ILN_4336 GBV_ILN_4338 GBV_ILN_4367 GBV_ILN_4700 AR 15 2024 1 434-441
spelling	10.1002/jcsm.13401 doi (DE-627)DOAJ095985301 (DE-599)DOAJbf50e2209dd4425cb93889dd11b0c44a DE-627 ger DE-627 rakwb eng RC925-935 QM1-695 Ga Yang Shim verfasserin aut Cross‐sectional and longitudinal association between atrial fibrillation and sarcopenia: Findings from the Korean frailty and aging cohort study 2024 Text txt rdacontent Computermedien c rdamedia Online-Ressource cr rdacarrier Abstract Background Sarcopenia is commonly observed in patients with cardiovascular diseases. However, studies on the association between sarcopenia and atrial fibrillation and their causal relationships are limited. We performed cross‐sectional and longitudinal analyses to investigate the association between sarcopenia and atrial fibrillation among community‐dwelling older adults. Methods A total of 2225 participants from the Korean Frailty and Aging Cohort Study (KFACS) from 2016 to 2017 were included in this cross‐sectional analysis. Sarcopenia was defined according to the Asian Working Group for Sarcopenia 2019 consensus. Atrial fibrillation was diagnosed on the basis of electrocardiographic findings. We investigated whether atrial fibrillation increased the risk of incident sarcopenia 2 years later and whether sarcopenia, in turn, increased the 2‐year risk of developing atrial fibrillation using KFACS data from 2018 to 2019. Results Of the 2225 participants (54.2% women; mean age 76.0 ± 3.9 years), 509 (22.9%) had sarcopenia at baseline. In the cross‐sectional analysis, sarcopenia was associated with atrial fibrillation after multivariate adjustment [odd ratio (OR), 2.127; 95% confidence interval (CI), 1.240–3.648; P = 0.006]. Among the sarcopenia components, low physical performance was associated with atrial fibrillation (OR, 1.872; 95% CI, 1.123–3.120; P = 0.016). During the 2‐year follow‐up period, atrial fibrillation was not associated with new‐onset of sarcopenia (OR, 1.483; 95% CI, 0.597–3.685; P = 0.396), and sarcopenia also did not significantly increase the risk of incident atrial fibrillation (OR, 1.120; 95% CI, 0.384–3.264; P = 0.836). Conclusions Although we found a significant association between sarcopenia and atrial fibrillation in a cross‐sectional analysis, we could not establish a causal relationship between the two based on 2 years of follow‐up. Further research with long‐term follow‐up is required to identify causal relationship between atrial fibrillation and sarcopenia. Atrial fibrillation Longitudinal analysis Older adults Sarcopenia Diseases of the musculoskeletal system Human anatomy Miji Kim verfasserin aut Chang Won Won verfasserin aut In Journal of Cachexia, Sarcopenia and Muscle Wiley, 2016 15(2024), 1, Seite 434-441 (DE-627)642886121 (DE-600)2586864-0 21906009 nnns volume:15 year:2024 number:1 pages:434-441 https://doi.org/10.1002/jcsm.13401 kostenfrei https://doaj.org/article/bf50e2209dd4425cb93889dd11b0c44a kostenfrei https://doi.org/10.1002/jcsm.13401 kostenfrei https://doaj.org/toc/2190-5991 Journal toc kostenfrei https://doaj.org/toc/2190-6009 Journal toc kostenfrei GBV_USEFLAG_A SYSFLAG_A GBV_DOAJ GBV_ILN_20 GBV_ILN_22 GBV_ILN_23 GBV_ILN_24 GBV_ILN_31 GBV_ILN_39 GBV_ILN_40 GBV_ILN_60 GBV_ILN_62 GBV_ILN_63 GBV_ILN_65 GBV_ILN_69 GBV_ILN_73 GBV_ILN_74 GBV_ILN_95 GBV_ILN_105 GBV_ILN_110 GBV_ILN_151 GBV_ILN_161 GBV_ILN_170 GBV_ILN_171 GBV_ILN_206 GBV_ILN_213 GBV_ILN_224 GBV_ILN_230 GBV_ILN_285 GBV_ILN_293 GBV_ILN_602 GBV_ILN_636 GBV_ILN_2004 GBV_ILN_2005 GBV_ILN_2006 GBV_ILN_2007 GBV_ILN_2010 GBV_ILN_2011 GBV_ILN_2014 GBV_ILN_2026 GBV_ILN_2027 GBV_ILN_2034 GBV_ILN_2037 GBV_ILN_2038 GBV_ILN_2044 GBV_ILN_2048 GBV_ILN_2049 GBV_ILN_2050 GBV_ILN_2055 GBV_ILN_2056 GBV_ILN_2057 GBV_ILN_2059 GBV_ILN_2061 GBV_ILN_2064 GBV_ILN_2068 GBV_ILN_2088 GBV_ILN_2106 GBV_ILN_2108 GBV_ILN_2110 GBV_ILN_2111 GBV_ILN_2118 GBV_ILN_2122 GBV_ILN_2143 GBV_ILN_2144 GBV_ILN_2147 GBV_ILN_2148 GBV_ILN_2152 GBV_ILN_2153 GBV_ILN_2232 GBV_ILN_2470 GBV_ILN_2507 GBV_ILN_2522 GBV_ILN_4012 GBV_ILN_4035 GBV_ILN_4037 GBV_ILN_4046 GBV_ILN_4112 GBV_ILN_4125 GBV_ILN_4126 GBV_ILN_4242 GBV_ILN_4249 GBV_ILN_4251 GBV_ILN_4305 GBV_ILN_4306 GBV_ILN_4307 GBV_ILN_4313 GBV_ILN_4322 GBV_ILN_4323 GBV_ILN_4324 GBV_ILN_4325 GBV_ILN_4326 GBV_ILN_4333 GBV_ILN_4334 GBV_ILN_4335 GBV_ILN_4336 GBV_ILN_4338 GBV_ILN_4367 GBV_ILN_4700 AR 15 2024 1 434-441
allfields_unstemmed	10.1002/jcsm.13401 doi (DE-627)DOAJ095985301 (DE-599)DOAJbf50e2209dd4425cb93889dd11b0c44a DE-627 ger DE-627 rakwb eng RC925-935 QM1-695 Ga Yang Shim verfasserin aut Cross‐sectional and longitudinal association between atrial fibrillation and sarcopenia: Findings from the Korean frailty and aging cohort study 2024 Text txt rdacontent Computermedien c rdamedia Online-Ressource cr rdacarrier Abstract Background Sarcopenia is commonly observed in patients with cardiovascular diseases. However, studies on the association between sarcopenia and atrial fibrillation and their causal relationships are limited. We performed cross‐sectional and longitudinal analyses to investigate the association between sarcopenia and atrial fibrillation among community‐dwelling older adults. Methods A total of 2225 participants from the Korean Frailty and Aging Cohort Study (KFACS) from 2016 to 2017 were included in this cross‐sectional analysis. Sarcopenia was defined according to the Asian Working Group for Sarcopenia 2019 consensus. Atrial fibrillation was diagnosed on the basis of electrocardiographic findings. We investigated whether atrial fibrillation increased the risk of incident sarcopenia 2 years later and whether sarcopenia, in turn, increased the 2‐year risk of developing atrial fibrillation using KFACS data from 2018 to 2019. Results Of the 2225 participants (54.2% women; mean age 76.0 ± 3.9 years), 509 (22.9%) had sarcopenia at baseline. In the cross‐sectional analysis, sarcopenia was associated with atrial fibrillation after multivariate adjustment [odd ratio (OR), 2.127; 95% confidence interval (CI), 1.240–3.648; P = 0.006]. Among the sarcopenia components, low physical performance was associated with atrial fibrillation (OR, 1.872; 95% CI, 1.123–3.120; P = 0.016). During the 2‐year follow‐up period, atrial fibrillation was not associated with new‐onset of sarcopenia (OR, 1.483; 95% CI, 0.597–3.685; P = 0.396), and sarcopenia also did not significantly increase the risk of incident atrial fibrillation (OR, 1.120; 95% CI, 0.384–3.264; P = 0.836). Conclusions Although we found a significant association between sarcopenia and atrial fibrillation in a cross‐sectional analysis, we could not establish a causal relationship between the two based on 2 years of follow‐up. Further research with long‐term follow‐up is required to identify causal relationship between atrial fibrillation and sarcopenia. Atrial fibrillation Longitudinal analysis Older adults Sarcopenia Diseases of the musculoskeletal system Human anatomy Miji Kim verfasserin aut Chang Won Won verfasserin aut In Journal of Cachexia, Sarcopenia and Muscle Wiley, 2016 15(2024), 1, Seite 434-441 (DE-627)642886121 (DE-600)2586864-0 21906009 nnns volume:15 year:2024 number:1 pages:434-441 https://doi.org/10.1002/jcsm.13401 kostenfrei https://doaj.org/article/bf50e2209dd4425cb93889dd11b0c44a kostenfrei https://doi.org/10.1002/jcsm.13401 kostenfrei https://doaj.org/toc/2190-5991 Journal toc kostenfrei https://doaj.org/toc/2190-6009 Journal toc kostenfrei GBV_USEFLAG_A SYSFLAG_A GBV_DOAJ GBV_ILN_20 GBV_ILN_22 GBV_ILN_23 GBV_ILN_24 GBV_ILN_31 GBV_ILN_39 GBV_ILN_40 GBV_ILN_60 GBV_ILN_62 GBV_ILN_63 GBV_ILN_65 GBV_ILN_69 GBV_ILN_73 GBV_ILN_74 GBV_ILN_95 GBV_ILN_105 GBV_ILN_110 GBV_ILN_151 GBV_ILN_161 GBV_ILN_170 GBV_ILN_171 GBV_ILN_206 GBV_ILN_213 GBV_ILN_224 GBV_ILN_230 GBV_ILN_285 GBV_ILN_293 GBV_ILN_602 GBV_ILN_636 GBV_ILN_2004 GBV_ILN_2005 GBV_ILN_2006 GBV_ILN_2007 GBV_ILN_2010 GBV_ILN_2011 GBV_ILN_2014 GBV_ILN_2026 GBV_ILN_2027 GBV_ILN_2034 GBV_ILN_2037 GBV_ILN_2038 GBV_ILN_2044 GBV_ILN_2048 GBV_ILN_2049 GBV_ILN_2050 GBV_ILN_2055 GBV_ILN_2056 GBV_ILN_2057 GBV_ILN_2059 GBV_ILN_2061 GBV_ILN_2064 GBV_ILN_2068 GBV_ILN_2088 GBV_ILN_2106 GBV_ILN_2108 GBV_ILN_2110 GBV_ILN_2111 GBV_ILN_2118 GBV_ILN_2122 GBV_ILN_2143 GBV_ILN_2144 GBV_ILN_2147 GBV_ILN_2148 GBV_ILN_2152 GBV_ILN_2153 GBV_ILN_2232 GBV_ILN_2470 GBV_ILN_2507 GBV_ILN_2522 GBV_ILN_4012 GBV_ILN_4035 GBV_ILN_4037 GBV_ILN_4046 GBV_ILN_4112 GBV_ILN_4125 GBV_ILN_4126 GBV_ILN_4242 GBV_ILN_4249 GBV_ILN_4251 GBV_ILN_4305 GBV_ILN_4306 GBV_ILN_4307 GBV_ILN_4313 GBV_ILN_4322 GBV_ILN_4323 GBV_ILN_4324 GBV_ILN_4325 GBV_ILN_4326 GBV_ILN_4333 GBV_ILN_4334 GBV_ILN_4335 GBV_ILN_4336 GBV_ILN_4338 GBV_ILN_4367 GBV_ILN_4700 AR 15 2024 1 434-441
allfieldsGer	10.1002/jcsm.13401 doi (DE-627)DOAJ095985301 (DE-599)DOAJbf50e2209dd4425cb93889dd11b0c44a DE-627 ger DE-627 rakwb eng RC925-935 QM1-695 Ga Yang Shim verfasserin aut Cross‐sectional and longitudinal association between atrial fibrillation and sarcopenia: Findings from the Korean frailty and aging cohort study 2024 Text txt rdacontent Computermedien c rdamedia Online-Ressource cr rdacarrier Abstract Background Sarcopenia is commonly observed in patients with cardiovascular diseases. However, studies on the association between sarcopenia and atrial fibrillation and their causal relationships are limited. We performed cross‐sectional and longitudinal analyses to investigate the association between sarcopenia and atrial fibrillation among community‐dwelling older adults. Methods A total of 2225 participants from the Korean Frailty and Aging Cohort Study (KFACS) from 2016 to 2017 were included in this cross‐sectional analysis. Sarcopenia was defined according to the Asian Working Group for Sarcopenia 2019 consensus. Atrial fibrillation was diagnosed on the basis of electrocardiographic findings. We investigated whether atrial fibrillation increased the risk of incident sarcopenia 2 years later and whether sarcopenia, in turn, increased the 2‐year risk of developing atrial fibrillation using KFACS data from 2018 to 2019. Results Of the 2225 participants (54.2% women; mean age 76.0 ± 3.9 years), 509 (22.9%) had sarcopenia at baseline. In the cross‐sectional analysis, sarcopenia was associated with atrial fibrillation after multivariate adjustment [odd ratio (OR), 2.127; 95% confidence interval (CI), 1.240–3.648; P = 0.006]. Among the sarcopenia components, low physical performance was associated with atrial fibrillation (OR, 1.872; 95% CI, 1.123–3.120; P = 0.016). During the 2‐year follow‐up period, atrial fibrillation was not associated with new‐onset of sarcopenia (OR, 1.483; 95% CI, 0.597–3.685; P = 0.396), and sarcopenia also did not significantly increase the risk of incident atrial fibrillation (OR, 1.120; 95% CI, 0.384–3.264; P = 0.836). Conclusions Although we found a significant association between sarcopenia and atrial fibrillation in a cross‐sectional analysis, we could not establish a causal relationship between the two based on 2 years of follow‐up. Further research with long‐term follow‐up is required to identify causal relationship between atrial fibrillation and sarcopenia. Atrial fibrillation Longitudinal analysis Older adults Sarcopenia Diseases of the musculoskeletal system Human anatomy Miji Kim verfasserin aut Chang Won Won verfasserin aut In Journal of Cachexia, Sarcopenia and Muscle Wiley, 2016 15(2024), 1, Seite 434-441 (DE-627)642886121 (DE-600)2586864-0 21906009 nnns volume:15 year:2024 number:1 pages:434-441 https://doi.org/10.1002/jcsm.13401 kostenfrei https://doaj.org/article/bf50e2209dd4425cb93889dd11b0c44a kostenfrei https://doi.org/10.1002/jcsm.13401 kostenfrei https://doaj.org/toc/2190-5991 Journal toc kostenfrei https://doaj.org/toc/2190-6009 Journal toc kostenfrei GBV_USEFLAG_A SYSFLAG_A GBV_DOAJ GBV_ILN_20 GBV_ILN_22 GBV_ILN_23 GBV_ILN_24 GBV_ILN_31 GBV_ILN_39 GBV_ILN_40 GBV_ILN_60 GBV_ILN_62 GBV_ILN_63 GBV_ILN_65 GBV_ILN_69 GBV_ILN_73 GBV_ILN_74 GBV_ILN_95 GBV_ILN_105 GBV_ILN_110 GBV_ILN_151 GBV_ILN_161 GBV_ILN_170 GBV_ILN_171 GBV_ILN_206 GBV_ILN_213 GBV_ILN_224 GBV_ILN_230 GBV_ILN_285 GBV_ILN_293 GBV_ILN_602 GBV_ILN_636 GBV_ILN_2004 GBV_ILN_2005 GBV_ILN_2006 GBV_ILN_2007 GBV_ILN_2010 GBV_ILN_2011 GBV_ILN_2014 GBV_ILN_2026 GBV_ILN_2027 GBV_ILN_2034 GBV_ILN_2037 GBV_ILN_2038 GBV_ILN_2044 GBV_ILN_2048 GBV_ILN_2049 GBV_ILN_2050 GBV_ILN_2055 GBV_ILN_2056 GBV_ILN_2057 GBV_ILN_2059 GBV_ILN_2061 GBV_ILN_2064 GBV_ILN_2068 GBV_ILN_2088 GBV_ILN_2106 GBV_ILN_2108 GBV_ILN_2110 GBV_ILN_2111 GBV_ILN_2118 GBV_ILN_2122 GBV_ILN_2143 GBV_ILN_2144 GBV_ILN_2147 GBV_ILN_2148 GBV_ILN_2152 GBV_ILN_2153 GBV_ILN_2232 GBV_ILN_2470 GBV_ILN_2507 GBV_ILN_2522 GBV_ILN_4012 GBV_ILN_4035 GBV_ILN_4037 GBV_ILN_4046 GBV_ILN_4112 GBV_ILN_4125 GBV_ILN_4126 GBV_ILN_4242 GBV_ILN_4249 GBV_ILN_4251 GBV_ILN_4305 GBV_ILN_4306 GBV_ILN_4307 GBV_ILN_4313 GBV_ILN_4322 GBV_ILN_4323 GBV_ILN_4324 GBV_ILN_4325 GBV_ILN_4326 GBV_ILN_4333 GBV_ILN_4334 GBV_ILN_4335 GBV_ILN_4336 GBV_ILN_4338 GBV_ILN_4367 GBV_ILN_4700 AR 15 2024 1 434-441
allfieldsSound	10.1002/jcsm.13401 doi (DE-627)DOAJ095985301 (DE-599)DOAJbf50e2209dd4425cb93889dd11b0c44a DE-627 ger DE-627 rakwb eng RC925-935 QM1-695 Ga Yang Shim verfasserin aut Cross‐sectional and longitudinal association between atrial fibrillation and sarcopenia: Findings from the Korean frailty and aging cohort study 2024 Text txt rdacontent Computermedien c rdamedia Online-Ressource cr rdacarrier Abstract Background Sarcopenia is commonly observed in patients with cardiovascular diseases. However, studies on the association between sarcopenia and atrial fibrillation and their causal relationships are limited. We performed cross‐sectional and longitudinal analyses to investigate the association between sarcopenia and atrial fibrillation among community‐dwelling older adults. Methods A total of 2225 participants from the Korean Frailty and Aging Cohort Study (KFACS) from 2016 to 2017 were included in this cross‐sectional analysis. Sarcopenia was defined according to the Asian Working Group for Sarcopenia 2019 consensus. Atrial fibrillation was diagnosed on the basis of electrocardiographic findings. We investigated whether atrial fibrillation increased the risk of incident sarcopenia 2 years later and whether sarcopenia, in turn, increased the 2‐year risk of developing atrial fibrillation using KFACS data from 2018 to 2019. Results Of the 2225 participants (54.2% women; mean age 76.0 ± 3.9 years), 509 (22.9%) had sarcopenia at baseline. In the cross‐sectional analysis, sarcopenia was associated with atrial fibrillation after multivariate adjustment [odd ratio (OR), 2.127; 95% confidence interval (CI), 1.240–3.648; P = 0.006]. Among the sarcopenia components, low physical performance was associated with atrial fibrillation (OR, 1.872; 95% CI, 1.123–3.120; P = 0.016). During the 2‐year follow‐up period, atrial fibrillation was not associated with new‐onset of sarcopenia (OR, 1.483; 95% CI, 0.597–3.685; P = 0.396), and sarcopenia also did not significantly increase the risk of incident atrial fibrillation (OR, 1.120; 95% CI, 0.384–3.264; P = 0.836). Conclusions Although we found a significant association between sarcopenia and atrial fibrillation in a cross‐sectional analysis, we could not establish a causal relationship between the two based on 2 years of follow‐up. Further research with long‐term follow‐up is required to identify causal relationship between atrial fibrillation and sarcopenia. Atrial fibrillation Longitudinal analysis Older adults Sarcopenia Diseases of the musculoskeletal system Human anatomy Miji Kim verfasserin aut Chang Won Won verfasserin aut In Journal of Cachexia, Sarcopenia and Muscle Wiley, 2016 15(2024), 1, Seite 434-441 (DE-627)642886121 (DE-600)2586864-0 21906009 nnns volume:15 year:2024 number:1 pages:434-441 https://doi.org/10.1002/jcsm.13401 kostenfrei https://doaj.org/article/bf50e2209dd4425cb93889dd11b0c44a kostenfrei https://doi.org/10.1002/jcsm.13401 kostenfrei https://doaj.org/toc/2190-5991 Journal toc kostenfrei https://doaj.org/toc/2190-6009 Journal toc kostenfrei GBV_USEFLAG_A SYSFLAG_A GBV_DOAJ GBV_ILN_20 GBV_ILN_22 GBV_ILN_23 GBV_ILN_24 GBV_ILN_31 GBV_ILN_39 GBV_ILN_40 GBV_ILN_60 GBV_ILN_62 GBV_ILN_63 GBV_ILN_65 GBV_ILN_69 GBV_ILN_73 GBV_ILN_74 GBV_ILN_95 GBV_ILN_105 GBV_ILN_110 GBV_ILN_151 GBV_ILN_161 GBV_ILN_170 GBV_ILN_171 GBV_ILN_206 GBV_ILN_213 GBV_ILN_224 GBV_ILN_230 GBV_ILN_285 GBV_ILN_293 GBV_ILN_602 GBV_ILN_636 GBV_ILN_2004 GBV_ILN_2005 GBV_ILN_2006 GBV_ILN_2007 GBV_ILN_2010 GBV_ILN_2011 GBV_ILN_2014 GBV_ILN_2026 GBV_ILN_2027 GBV_ILN_2034 GBV_ILN_2037 GBV_ILN_2038 GBV_ILN_2044 GBV_ILN_2048 GBV_ILN_2049 GBV_ILN_2050 GBV_ILN_2055 GBV_ILN_2056 GBV_ILN_2057 GBV_ILN_2059 GBV_ILN_2061 GBV_ILN_2064 GBV_ILN_2068 GBV_ILN_2088 GBV_ILN_2106 GBV_ILN_2108 GBV_ILN_2110 GBV_ILN_2111 GBV_ILN_2118 GBV_ILN_2122 GBV_ILN_2143 GBV_ILN_2144 GBV_ILN_2147 GBV_ILN_2148 GBV_ILN_2152 GBV_ILN_2153 GBV_ILN_2232 GBV_ILN_2470 GBV_ILN_2507 GBV_ILN_2522 GBV_ILN_4012 GBV_ILN_4035 GBV_ILN_4037 GBV_ILN_4046 GBV_ILN_4112 GBV_ILN_4125 GBV_ILN_4126 GBV_ILN_4242 GBV_ILN_4249 GBV_ILN_4251 GBV_ILN_4305 GBV_ILN_4306 GBV_ILN_4307 GBV_ILN_4313 GBV_ILN_4322 GBV_ILN_4323 GBV_ILN_4324 GBV_ILN_4325 GBV_ILN_4326 GBV_ILN_4333 GBV_ILN_4334 GBV_ILN_4335 GBV_ILN_4336 GBV_ILN_4338 GBV_ILN_4367 GBV_ILN_4700 AR 15 2024 1 434-441
language	English
source	In Journal of Cachexia, Sarcopenia and Muscle 15(2024), 1, Seite 434-441 volume:15 year:2024 number:1 pages:434-441
sourceStr	In Journal of Cachexia, Sarcopenia and Muscle 15(2024), 1, Seite 434-441 volume:15 year:2024 number:1 pages:434-441
format_phy_str_mv	Article
institution	findex.gbv.de
topic_facet	Atrial fibrillation Longitudinal analysis Older adults Sarcopenia Diseases of the musculoskeletal system Human anatomy
isfreeaccess_bool	true
container_title	Journal of Cachexia, Sarcopenia and Muscle
authorswithroles_txt_mv	Ga Yang Shim @@aut@@ Miji Kim @@aut@@ Chang Won Won @@aut@@
publishDateDaySort_date	2024-01-01T00:00:00Z
hierarchy_top_id	642886121
id	DOAJ095985301
language_de	englisch
fullrecord	<?xml version="1.0" encoding="UTF-8"?><collection xmlns="http://www.loc.gov/MARC21/slim"><record><leader>01000naa a22002652 4500</leader><controlfield tag="001">DOAJ095985301</controlfield><controlfield tag="003">DE-627</controlfield><controlfield tag="005">20240413135236.0</controlfield><controlfield tag="007">cr uuu---uuuuu</controlfield><controlfield tag="008">240413s2024 xx \|\|\|\|\|o 00\| \|\|eng c</controlfield><datafield tag="024" ind1="7" ind2=" "><subfield code="a">10.1002/jcsm.13401</subfield><subfield code="2">doi</subfield></datafield><datafield tag="035" ind1=" " ind2=" "><subfield code="a">(DE-627)DOAJ095985301</subfield></datafield><datafield tag="035" ind1=" " ind2=" "><subfield code="a">(DE-599)DOAJbf50e2209dd4425cb93889dd11b0c44a</subfield></datafield><datafield tag="040" ind1=" " ind2=" "><subfield code="a">DE-627</subfield><subfield code="b">ger</subfield><subfield code="c">DE-627</subfield><subfield code="e">rakwb</subfield></datafield><datafield tag="041" ind1=" " ind2=" "><subfield code="a">eng</subfield></datafield><datafield tag="050" ind1=" " ind2="0"><subfield code="a">RC925-935</subfield></datafield><datafield tag="050" ind1=" " ind2="0"><subfield code="a">QM1-695</subfield></datafield><datafield tag="100" ind1="0" ind2=" "><subfield code="a">Ga Yang Shim</subfield><subfield code="e">verfasserin</subfield><subfield code="4">aut</subfield></datafield><datafield tag="245" ind1="1" ind2="0"><subfield code="a">Cross‐sectional and longitudinal association between atrial fibrillation and sarcopenia: Findings from the Korean frailty and aging cohort study</subfield></datafield><datafield tag="264" ind1=" " ind2="1"><subfield code="c">2024</subfield></datafield><datafield tag="336" ind1=" " ind2=" "><subfield code="a">Text</subfield><subfield code="b">txt</subfield><subfield code="2">rdacontent</subfield></datafield><datafield tag="337" ind1=" " ind2=" "><subfield code="a">Computermedien</subfield><subfield code="b">c</subfield><subfield code="2">rdamedia</subfield></datafield><datafield tag="338" ind1=" " ind2=" "><subfield code="a">Online-Ressource</subfield><subfield code="b">cr</subfield><subfield code="2">rdacarrier</subfield></datafield><datafield tag="520" ind1=" " ind2=" "><subfield code="a">Abstract Background Sarcopenia is commonly observed in patients with cardiovascular diseases. However, studies on the association between sarcopenia and atrial fibrillation and their causal relationships are limited. We performed cross‐sectional and longitudinal analyses to investigate the association between sarcopenia and atrial fibrillation among community‐dwelling older adults. Methods A total of 2225 participants from the Korean Frailty and Aging Cohort Study (KFACS) from 2016 to 2017 were included in this cross‐sectional analysis. Sarcopenia was defined according to the Asian Working Group for Sarcopenia 2019 consensus. Atrial fibrillation was diagnosed on the basis of electrocardiographic findings. We investigated whether atrial fibrillation increased the risk of incident sarcopenia 2 years later and whether sarcopenia, in turn, increased the 2‐year risk of developing atrial fibrillation using KFACS data from 2018 to 2019. Results Of the 2225 participants (54.2% women; mean age 76.0 ± 3.9 years), 509 (22.9%) had sarcopenia at baseline. In the cross‐sectional analysis, sarcopenia was associated with atrial fibrillation after multivariate adjustment [odd ratio (OR), 2.127; 95% confidence interval (CI), 1.240–3.648; P = 0.006]. Among the sarcopenia components, low physical performance was associated with atrial fibrillation (OR, 1.872; 95% CI, 1.123–3.120; P = 0.016). During the 2‐year follow‐up period, atrial fibrillation was not associated with new‐onset of sarcopenia (OR, 1.483; 95% CI, 0.597–3.685; P = 0.396), and sarcopenia also did not significantly increase the risk of incident atrial fibrillation (OR, 1.120; 95% CI, 0.384–3.264; P = 0.836). Conclusions Although we found a significant association between sarcopenia and atrial fibrillation in a cross‐sectional analysis, we could not establish a causal relationship between the two based on 2 years of follow‐up. Further research with long‐term follow‐up is required to identify causal relationship between atrial fibrillation and sarcopenia.</subfield></datafield><datafield tag="650" ind1=" " ind2="4"><subfield code="a">Atrial fibrillation</subfield></datafield><datafield tag="650" ind1=" " ind2="4"><subfield code="a">Longitudinal analysis</subfield></datafield><datafield tag="650" ind1=" " ind2="4"><subfield code="a">Older adults</subfield></datafield><datafield tag="650" ind1=" " ind2="4"><subfield code="a">Sarcopenia</subfield></datafield><datafield tag="653" ind1=" " ind2="0"><subfield code="a">Diseases of the musculoskeletal system</subfield></datafield><datafield tag="653" ind1=" " ind2="0"><subfield code="a">Human anatomy</subfield></datafield><datafield tag="700" ind1="0" ind2=" "><subfield code="a">Miji Kim</subfield><subfield code="e">verfasserin</subfield><subfield code="4">aut</subfield></datafield><datafield tag="700" ind1="0" ind2=" "><subfield code="a">Chang Won 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callnumber-first	R - Medicine
author	Ga Yang Shim
spellingShingle	Ga Yang Shim misc RC925-935 misc QM1-695 misc Atrial fibrillation misc Longitudinal analysis misc Older adults misc Sarcopenia misc Diseases of the musculoskeletal system misc Human anatomy Cross‐sectional and longitudinal association between atrial fibrillation and sarcopenia: Findings from the Korean frailty and aging cohort study
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topic_title	RC925-935 QM1-695 Cross‐sectional and longitudinal association between atrial fibrillation and sarcopenia: Findings from the Korean frailty and aging cohort study Atrial fibrillation Longitudinal analysis Older adults Sarcopenia
topic	misc RC925-935 misc QM1-695 misc Atrial fibrillation misc Longitudinal analysis misc Older adults misc Sarcopenia misc Diseases of the musculoskeletal system misc Human anatomy
topic_unstemmed	misc RC925-935 misc QM1-695 misc Atrial fibrillation misc Longitudinal analysis misc Older adults misc Sarcopenia misc Diseases of the musculoskeletal system misc Human anatomy
topic_browse	misc RC925-935 misc QM1-695 misc Atrial fibrillation misc Longitudinal analysis misc Older adults misc Sarcopenia misc Diseases of the musculoskeletal system misc Human anatomy
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title	Cross‐sectional and longitudinal association between atrial fibrillation and sarcopenia: Findings from the Korean frailty and aging cohort study
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title_full	Cross‐sectional and longitudinal association between atrial fibrillation and sarcopenia: Findings from the Korean frailty and aging cohort study
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author_browse	Ga Yang Shim Miji Kim Chang Won Won
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title_sort	cross‐sectional and longitudinal association between atrial fibrillation and sarcopenia: findings from the korean frailty and aging cohort study
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title_auth	Cross‐sectional and longitudinal association between atrial fibrillation and sarcopenia: Findings from the Korean frailty and aging cohort study
abstract	Abstract Background Sarcopenia is commonly observed in patients with cardiovascular diseases. However, studies on the association between sarcopenia and atrial fibrillation and their causal relationships are limited. We performed cross‐sectional and longitudinal analyses to investigate the association between sarcopenia and atrial fibrillation among community‐dwelling older adults. Methods A total of 2225 participants from the Korean Frailty and Aging Cohort Study (KFACS) from 2016 to 2017 were included in this cross‐sectional analysis. Sarcopenia was defined according to the Asian Working Group for Sarcopenia 2019 consensus. Atrial fibrillation was diagnosed on the basis of electrocardiographic findings. We investigated whether atrial fibrillation increased the risk of incident sarcopenia 2 years later and whether sarcopenia, in turn, increased the 2‐year risk of developing atrial fibrillation using KFACS data from 2018 to 2019. Results Of the 2225 participants (54.2% women; mean age 76.0 ± 3.9 years), 509 (22.9%) had sarcopenia at baseline. In the cross‐sectional analysis, sarcopenia was associated with atrial fibrillation after multivariate adjustment [odd ratio (OR), 2.127; 95% confidence interval (CI), 1.240–3.648; P = 0.006]. Among the sarcopenia components, low physical performance was associated with atrial fibrillation (OR, 1.872; 95% CI, 1.123–3.120; P = 0.016). During the 2‐year follow‐up period, atrial fibrillation was not associated with new‐onset of sarcopenia (OR, 1.483; 95% CI, 0.597–3.685; P = 0.396), and sarcopenia also did not significantly increase the risk of incident atrial fibrillation (OR, 1.120; 95% CI, 0.384–3.264; P = 0.836). Conclusions Although we found a significant association between sarcopenia and atrial fibrillation in a cross‐sectional analysis, we could not establish a causal relationship between the two based on 2 years of follow‐up. Further research with long‐term follow‐up is required to identify causal relationship between atrial fibrillation and sarcopenia.
abstractGer	Abstract Background Sarcopenia is commonly observed in patients with cardiovascular diseases. However, studies on the association between sarcopenia and atrial fibrillation and their causal relationships are limited. We performed cross‐sectional and longitudinal analyses to investigate the association between sarcopenia and atrial fibrillation among community‐dwelling older adults. Methods A total of 2225 participants from the Korean Frailty and Aging Cohort Study (KFACS) from 2016 to 2017 were included in this cross‐sectional analysis. Sarcopenia was defined according to the Asian Working Group for Sarcopenia 2019 consensus. Atrial fibrillation was diagnosed on the basis of electrocardiographic findings. We investigated whether atrial fibrillation increased the risk of incident sarcopenia 2 years later and whether sarcopenia, in turn, increased the 2‐year risk of developing atrial fibrillation using KFACS data from 2018 to 2019. Results Of the 2225 participants (54.2% women; mean age 76.0 ± 3.9 years), 509 (22.9%) had sarcopenia at baseline. In the cross‐sectional analysis, sarcopenia was associated with atrial fibrillation after multivariate adjustment [odd ratio (OR), 2.127; 95% confidence interval (CI), 1.240–3.648; P = 0.006]. Among the sarcopenia components, low physical performance was associated with atrial fibrillation (OR, 1.872; 95% CI, 1.123–3.120; P = 0.016). During the 2‐year follow‐up period, atrial fibrillation was not associated with new‐onset of sarcopenia (OR, 1.483; 95% CI, 0.597–3.685; P = 0.396), and sarcopenia also did not significantly increase the risk of incident atrial fibrillation (OR, 1.120; 95% CI, 0.384–3.264; P = 0.836). Conclusions Although we found a significant association between sarcopenia and atrial fibrillation in a cross‐sectional analysis, we could not establish a causal relationship between the two based on 2 years of follow‐up. Further research with long‐term follow‐up is required to identify causal relationship between atrial fibrillation and sarcopenia.
abstract_unstemmed	Abstract Background Sarcopenia is commonly observed in patients with cardiovascular diseases. However, studies on the association between sarcopenia and atrial fibrillation and their causal relationships are limited. We performed cross‐sectional and longitudinal analyses to investigate the association between sarcopenia and atrial fibrillation among community‐dwelling older adults. Methods A total of 2225 participants from the Korean Frailty and Aging Cohort Study (KFACS) from 2016 to 2017 were included in this cross‐sectional analysis. Sarcopenia was defined according to the Asian Working Group for Sarcopenia 2019 consensus. Atrial fibrillation was diagnosed on the basis of electrocardiographic findings. We investigated whether atrial fibrillation increased the risk of incident sarcopenia 2 years later and whether sarcopenia, in turn, increased the 2‐year risk of developing atrial fibrillation using KFACS data from 2018 to 2019. Results Of the 2225 participants (54.2% women; mean age 76.0 ± 3.9 years), 509 (22.9%) had sarcopenia at baseline. In the cross‐sectional analysis, sarcopenia was associated with atrial fibrillation after multivariate adjustment [odd ratio (OR), 2.127; 95% confidence interval (CI), 1.240–3.648; P = 0.006]. Among the sarcopenia components, low physical performance was associated with atrial fibrillation (OR, 1.872; 95% CI, 1.123–3.120; P = 0.016). During the 2‐year follow‐up period, atrial fibrillation was not associated with new‐onset of sarcopenia (OR, 1.483; 95% CI, 0.597–3.685; P = 0.396), and sarcopenia also did not significantly increase the risk of incident atrial fibrillation (OR, 1.120; 95% CI, 0.384–3.264; P = 0.836). Conclusions Although we found a significant association between sarcopenia and atrial fibrillation in a cross‐sectional analysis, we could not establish a causal relationship between the two based on 2 years of follow‐up. Further research with long‐term follow‐up is required to identify causal relationship between atrial fibrillation and sarcopenia.
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title_short	Cross‐sectional and longitudinal association between atrial fibrillation and sarcopenia: Findings from the Korean frailty and aging cohort study
url	https://doi.org/10.1002/jcsm.13401 https://doaj.org/article/bf50e2209dd4425cb93889dd11b0c44a https://doaj.org/toc/2190-5991 https://doaj.org/toc/2190-6009
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up_date	2024-07-03T17:43:44.848Z
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fullrecord_marcxml	<?xml version="1.0" encoding="UTF-8"?><collection xmlns="http://www.loc.gov/MARC21/slim"><record><leader>01000naa a22002652 4500</leader><controlfield tag="001">DOAJ095985301</controlfield><controlfield tag="003">DE-627</controlfield><controlfield tag="005">20240413135236.0</controlfield><controlfield tag="007">cr uuu---uuuuu</controlfield><controlfield tag="008">240413s2024 xx \|\|\|\|\|o 00\| \|\|eng c</controlfield><datafield tag="024" ind1="7" ind2=" "><subfield code="a">10.1002/jcsm.13401</subfield><subfield code="2">doi</subfield></datafield><datafield tag="035" ind1=" " ind2=" "><subfield code="a">(DE-627)DOAJ095985301</subfield></datafield><datafield tag="035" ind1=" " ind2=" "><subfield code="a">(DE-599)DOAJbf50e2209dd4425cb93889dd11b0c44a</subfield></datafield><datafield tag="040" ind1=" " ind2=" "><subfield code="a">DE-627</subfield><subfield code="b">ger</subfield><subfield code="c">DE-627</subfield><subfield code="e">rakwb</subfield></datafield><datafield tag="041" ind1=" " ind2=" "><subfield code="a">eng</subfield></datafield><datafield tag="050" ind1=" " ind2="0"><subfield code="a">RC925-935</subfield></datafield><datafield tag="050" ind1=" " ind2="0"><subfield code="a">QM1-695</subfield></datafield><datafield tag="100" ind1="0" ind2=" "><subfield code="a">Ga Yang Shim</subfield><subfield code="e">verfasserin</subfield><subfield code="4">aut</subfield></datafield><datafield tag="245" ind1="1" ind2="0"><subfield code="a">Cross‐sectional and longitudinal association between atrial fibrillation and sarcopenia: Findings from the Korean frailty and aging cohort study</subfield></datafield><datafield tag="264" ind1=" " ind2="1"><subfield code="c">2024</subfield></datafield><datafield tag="336" ind1=" " ind2=" "><subfield code="a">Text</subfield><subfield code="b">txt</subfield><subfield code="2">rdacontent</subfield></datafield><datafield tag="337" ind1=" " ind2=" "><subfield code="a">Computermedien</subfield><subfield code="b">c</subfield><subfield code="2">rdamedia</subfield></datafield><datafield tag="338" ind1=" " ind2=" "><subfield code="a">Online-Ressource</subfield><subfield code="b">cr</subfield><subfield code="2">rdacarrier</subfield></datafield><datafield tag="520" ind1=" " ind2=" "><subfield code="a">Abstract Background Sarcopenia is commonly observed in patients with cardiovascular diseases. However, studies on the association between sarcopenia and atrial fibrillation and their causal relationships are limited. We performed cross‐sectional and longitudinal analyses to investigate the association between sarcopenia and atrial fibrillation among community‐dwelling older adults. Methods A total of 2225 participants from the Korean Frailty and Aging Cohort Study (KFACS) from 2016 to 2017 were included in this cross‐sectional analysis. Sarcopenia was defined according to the Asian Working Group for Sarcopenia 2019 consensus. Atrial fibrillation was diagnosed on the basis of electrocardiographic findings. We investigated whether atrial fibrillation increased the risk of incident sarcopenia 2 years later and whether sarcopenia, in turn, increased the 2‐year risk of developing atrial fibrillation using KFACS data from 2018 to 2019. Results Of the 2225 participants (54.2% women; mean age 76.0 ± 3.9 years), 509 (22.9%) had sarcopenia at baseline. In the cross‐sectional analysis, sarcopenia was associated with atrial fibrillation after multivariate adjustment [odd ratio (OR), 2.127; 95% confidence interval (CI), 1.240–3.648; P = 0.006]. Among the sarcopenia components, low physical performance was associated with atrial fibrillation (OR, 1.872; 95% CI, 1.123–3.120; P = 0.016). During the 2‐year follow‐up period, atrial fibrillation was not associated with new‐onset of sarcopenia (OR, 1.483; 95% CI, 0.597–3.685; P = 0.396), and sarcopenia also did not significantly increase the risk of incident atrial fibrillation (OR, 1.120; 95% CI, 0.384–3.264; P = 0.836). Conclusions Although we found a significant association between sarcopenia and atrial fibrillation in a cross‐sectional analysis, we could not establish a causal relationship between the two based on 2 years of follow‐up. Further research with long‐term follow‐up is required to identify causal relationship between atrial fibrillation and sarcopenia.</subfield></datafield><datafield tag="650" ind1=" " ind2="4"><subfield code="a">Atrial fibrillation</subfield></datafield><datafield tag="650" ind1=" " ind2="4"><subfield code="a">Longitudinal analysis</subfield></datafield><datafield tag="650" ind1=" " ind2="4"><subfield code="a">Older adults</subfield></datafield><datafield tag="650" ind1=" " ind2="4"><subfield code="a">Sarcopenia</subfield></datafield><datafield tag="653" ind1=" " ind2="0"><subfield code="a">Diseases of the musculoskeletal system</subfield></datafield><datafield tag="653" ind1=" " ind2="0"><subfield code="a">Human anatomy</subfield></datafield><datafield tag="700" ind1="0" ind2=" "><subfield code="a">Miji Kim</subfield><subfield code="e">verfasserin</subfield><subfield code="4">aut</subfield></datafield><datafield tag="700" ind1="0" ind2=" "><subfield code="a">Chang Won 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Cross‐sectional and longitudinal association between atrial fibrillation and sarcopenia: Findings from the Korean frailty and aging cohort study

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