Non-Additive and Asymmetric Allelic Expression of <i<p38 mapk</i< in Hybrid Tilapia (<i<Oreochromis niloticus</i< ♀ × <i<O. aureus</i< ♂)

Hybridization is a widely used breeding technique in fish species that enhances desirable traits in cultured species through heterosis. However, the mechanism by which hybrids alter gene expression to form heterosis remains unclear. In this study, a group of hybrid tilapia was used to elucidate hete...
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Autor*in:	Zihui Liu [verfasserIn] Binglin Chen [verfasserIn] Zhiying Zou [verfasserIn] Dayu Li [verfasserIn] Jinglin Zhu [verfasserIn] Jie Yu [verfasserIn] Wei Xiao [verfasserIn] Hong Yang [verfasserIn]

Format:	E-Artikel
Sprache:	Englisch

Erschienen:	2024

Schlagwörter:	hybridization non-additive asymmetric allelic expression cis- and trans-acting elements

Übergeordnetes Werk:	In: Animals - MDPI AG, 2011, 14(2024), 2, p 266
Übergeordnetes Werk:	volume:14 ; year:2024 ; number:2, p 266

Links:	Link aufrufen Link aufrufen Link aufrufen Journal toc

DOI / URN:	10.3390/ani14020266

Katalog-ID:	DOAJ096398264

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allfields	10.3390/ani14020266 doi (DE-627)DOAJ096398264 (DE-599)DOAJ3e69c1ec7944422b8802c07adbcd6f18 DE-627 ger DE-627 rakwb eng SF600-1100 QL1-991 Zihui Liu verfasserin aut Non-Additive and Asymmetric Allelic Expression of <i<p38 mapk</i< in Hybrid Tilapia (<i<Oreochromis niloticus</i< ♀ × <i<O. aureus</i< ♂) 2024 Text txt rdacontent Computermedien c rdamedia Online-Ressource cr rdacarrier Hybridization is a widely used breeding technique in fish species that enhances desirable traits in cultured species through heterosis. However, the mechanism by which hybrids alter gene expression to form heterosis remains unclear. In this study, a group of hybrid tilapia was used to elucidate heterosis through interspecies crossing. Specifically, <i<p38</i< was analyzed to describe the regulation of gene expression variation in hybrid tilapia. Transcripts from the Nile tilapia allele were found to be significantly higher than those from the blue tilapia allele in hybrid individuals, indicating that the expression of <i<p38</i< was dominated by Nile tilapia sub-genomic alleles. The study also found a compensatory interaction of cis- and trans-acting elements of the Nile tilapia and blue tilapia sub-genomes, inducing a non-additive expression of <i<p38</i< in hybrids. Eight specific SNPs were identified in the <i<p38</i< promoter regions of Nile tilapia and blue tilapia, and were found to be promoter differences leading to differences in gene expression efficiencies between parental alleles using a dual-luciferase reporter system. This study provides insights into the non-additive expression patterns of key functional genes in fish hybrids related to growth and immunity response. hybridization non-additive asymmetric allelic expression cis- and trans-acting elements <i<p38 mapk</i< Veterinary medicine Zoology Binglin Chen verfasserin aut Zhiying Zou verfasserin aut Dayu Li verfasserin aut Jinglin Zhu verfasserin aut Jie Yu verfasserin aut Wei Xiao verfasserin aut Hong Yang verfasserin aut In Animals MDPI AG, 2011 14(2024), 2, p 266 (DE-627)657589306 (DE-600)2606558-7 20762615 nnns volume:14 year:2024 number:2, p 266 https://doi.org/10.3390/ani14020266 kostenfrei https://doaj.org/article/3e69c1ec7944422b8802c07adbcd6f18 kostenfrei https://www.mdpi.com/2076-2615/14/2/266 kostenfrei https://doaj.org/toc/2076-2615 Journal toc kostenfrei GBV_USEFLAG_A SYSFLAG_A GBV_DOAJ GBV_ILN_20 GBV_ILN_22 GBV_ILN_23 GBV_ILN_24 GBV_ILN_39 GBV_ILN_40 GBV_ILN_60 GBV_ILN_62 GBV_ILN_63 GBV_ILN_65 GBV_ILN_69 GBV_ILN_73 GBV_ILN_95 GBV_ILN_105 GBV_ILN_110 GBV_ILN_151 GBV_ILN_161 GBV_ILN_206 GBV_ILN_213 GBV_ILN_230 GBV_ILN_285 GBV_ILN_293 GBV_ILN_602 GBV_ILN_702 GBV_ILN_2001 GBV_ILN_2003 GBV_ILN_2005 GBV_ILN_2006 GBV_ILN_2008 GBV_ILN_2009 GBV_ILN_2010 GBV_ILN_2011 GBV_ILN_2014 GBV_ILN_2015 GBV_ILN_2020 GBV_ILN_2021 GBV_ILN_2025 GBV_ILN_2031 GBV_ILN_2044 GBV_ILN_2048 GBV_ILN_2050 GBV_ILN_2055 GBV_ILN_2056 GBV_ILN_2057 GBV_ILN_2061 GBV_ILN_2111 GBV_ILN_2190 GBV_ILN_4012 GBV_ILN_4037 GBV_ILN_4112 GBV_ILN_4125 GBV_ILN_4126 GBV_ILN_4249 GBV_ILN_4305 GBV_ILN_4306 GBV_ILN_4307 GBV_ILN_4313 GBV_ILN_4322 GBV_ILN_4323 GBV_ILN_4324 GBV_ILN_4325 GBV_ILN_4338 GBV_ILN_4367 GBV_ILN_4700 AR 14 2024 2, p 266
spelling	10.3390/ani14020266 doi (DE-627)DOAJ096398264 (DE-599)DOAJ3e69c1ec7944422b8802c07adbcd6f18 DE-627 ger DE-627 rakwb eng SF600-1100 QL1-991 Zihui Liu verfasserin aut Non-Additive and Asymmetric Allelic Expression of <i<p38 mapk</i< in Hybrid Tilapia (<i<Oreochromis niloticus</i< ♀ × <i<O. aureus</i< ♂) 2024 Text txt rdacontent Computermedien c rdamedia Online-Ressource cr rdacarrier Hybridization is a widely used breeding technique in fish species that enhances desirable traits in cultured species through heterosis. However, the mechanism by which hybrids alter gene expression to form heterosis remains unclear. In this study, a group of hybrid tilapia was used to elucidate heterosis through interspecies crossing. Specifically, <i<p38</i< was analyzed to describe the regulation of gene expression variation in hybrid tilapia. Transcripts from the Nile tilapia allele were found to be significantly higher than those from the blue tilapia allele in hybrid individuals, indicating that the expression of <i<p38</i< was dominated by Nile tilapia sub-genomic alleles. The study also found a compensatory interaction of cis- and trans-acting elements of the Nile tilapia and blue tilapia sub-genomes, inducing a non-additive expression of <i<p38</i< in hybrids. Eight specific SNPs were identified in the <i<p38</i< promoter regions of Nile tilapia and blue tilapia, and were found to be promoter differences leading to differences in gene expression efficiencies between parental alleles using a dual-luciferase reporter system. This study provides insights into the non-additive expression patterns of key functional genes in fish hybrids related to growth and immunity response. hybridization non-additive asymmetric allelic expression cis- and trans-acting elements <i<p38 mapk</i< Veterinary medicine Zoology Binglin Chen verfasserin aut Zhiying Zou verfasserin aut Dayu Li verfasserin aut Jinglin Zhu verfasserin aut Jie Yu verfasserin aut Wei Xiao verfasserin aut Hong Yang verfasserin aut In Animals MDPI AG, 2011 14(2024), 2, p 266 (DE-627)657589306 (DE-600)2606558-7 20762615 nnns volume:14 year:2024 number:2, p 266 https://doi.org/10.3390/ani14020266 kostenfrei https://doaj.org/article/3e69c1ec7944422b8802c07adbcd6f18 kostenfrei https://www.mdpi.com/2076-2615/14/2/266 kostenfrei https://doaj.org/toc/2076-2615 Journal toc kostenfrei GBV_USEFLAG_A SYSFLAG_A GBV_DOAJ GBV_ILN_20 GBV_ILN_22 GBV_ILN_23 GBV_ILN_24 GBV_ILN_39 GBV_ILN_40 GBV_ILN_60 GBV_ILN_62 GBV_ILN_63 GBV_ILN_65 GBV_ILN_69 GBV_ILN_73 GBV_ILN_95 GBV_ILN_105 GBV_ILN_110 GBV_ILN_151 GBV_ILN_161 GBV_ILN_206 GBV_ILN_213 GBV_ILN_230 GBV_ILN_285 GBV_ILN_293 GBV_ILN_602 GBV_ILN_702 GBV_ILN_2001 GBV_ILN_2003 GBV_ILN_2005 GBV_ILN_2006 GBV_ILN_2008 GBV_ILN_2009 GBV_ILN_2010 GBV_ILN_2011 GBV_ILN_2014 GBV_ILN_2015 GBV_ILN_2020 GBV_ILN_2021 GBV_ILN_2025 GBV_ILN_2031 GBV_ILN_2044 GBV_ILN_2048 GBV_ILN_2050 GBV_ILN_2055 GBV_ILN_2056 GBV_ILN_2057 GBV_ILN_2061 GBV_ILN_2111 GBV_ILN_2190 GBV_ILN_4012 GBV_ILN_4037 GBV_ILN_4112 GBV_ILN_4125 GBV_ILN_4126 GBV_ILN_4249 GBV_ILN_4305 GBV_ILN_4306 GBV_ILN_4307 GBV_ILN_4313 GBV_ILN_4322 GBV_ILN_4323 GBV_ILN_4324 GBV_ILN_4325 GBV_ILN_4338 GBV_ILN_4367 GBV_ILN_4700 AR 14 2024 2, p 266
allfields_unstemmed	10.3390/ani14020266 doi (DE-627)DOAJ096398264 (DE-599)DOAJ3e69c1ec7944422b8802c07adbcd6f18 DE-627 ger DE-627 rakwb eng SF600-1100 QL1-991 Zihui Liu verfasserin aut Non-Additive and Asymmetric Allelic Expression of <i<p38 mapk</i< in Hybrid Tilapia (<i<Oreochromis niloticus</i< ♀ × <i<O. aureus</i< ♂) 2024 Text txt rdacontent Computermedien c rdamedia Online-Ressource cr rdacarrier Hybridization is a widely used breeding technique in fish species that enhances desirable traits in cultured species through heterosis. However, the mechanism by which hybrids alter gene expression to form heterosis remains unclear. In this study, a group of hybrid tilapia was used to elucidate heterosis through interspecies crossing. Specifically, <i<p38</i< was analyzed to describe the regulation of gene expression variation in hybrid tilapia. Transcripts from the Nile tilapia allele were found to be significantly higher than those from the blue tilapia allele in hybrid individuals, indicating that the expression of <i<p38</i< was dominated by Nile tilapia sub-genomic alleles. The study also found a compensatory interaction of cis- and trans-acting elements of the Nile tilapia and blue tilapia sub-genomes, inducing a non-additive expression of <i<p38</i< in hybrids. Eight specific SNPs were identified in the <i<p38</i< promoter regions of Nile tilapia and blue tilapia, and were found to be promoter differences leading to differences in gene expression efficiencies between parental alleles using a dual-luciferase reporter system. This study provides insights into the non-additive expression patterns of key functional genes in fish hybrids related to growth and immunity response. hybridization non-additive asymmetric allelic expression cis- and trans-acting elements <i<p38 mapk</i< Veterinary medicine Zoology Binglin Chen verfasserin aut Zhiying Zou verfasserin aut Dayu Li verfasserin aut Jinglin Zhu verfasserin aut Jie Yu verfasserin aut Wei Xiao verfasserin aut Hong Yang verfasserin aut In Animals MDPI AG, 2011 14(2024), 2, p 266 (DE-627)657589306 (DE-600)2606558-7 20762615 nnns volume:14 year:2024 number:2, p 266 https://doi.org/10.3390/ani14020266 kostenfrei https://doaj.org/article/3e69c1ec7944422b8802c07adbcd6f18 kostenfrei https://www.mdpi.com/2076-2615/14/2/266 kostenfrei https://doaj.org/toc/2076-2615 Journal toc kostenfrei GBV_USEFLAG_A SYSFLAG_A GBV_DOAJ GBV_ILN_20 GBV_ILN_22 GBV_ILN_23 GBV_ILN_24 GBV_ILN_39 GBV_ILN_40 GBV_ILN_60 GBV_ILN_62 GBV_ILN_63 GBV_ILN_65 GBV_ILN_69 GBV_ILN_73 GBV_ILN_95 GBV_ILN_105 GBV_ILN_110 GBV_ILN_151 GBV_ILN_161 GBV_ILN_206 GBV_ILN_213 GBV_ILN_230 GBV_ILN_285 GBV_ILN_293 GBV_ILN_602 GBV_ILN_702 GBV_ILN_2001 GBV_ILN_2003 GBV_ILN_2005 GBV_ILN_2006 GBV_ILN_2008 GBV_ILN_2009 GBV_ILN_2010 GBV_ILN_2011 GBV_ILN_2014 GBV_ILN_2015 GBV_ILN_2020 GBV_ILN_2021 GBV_ILN_2025 GBV_ILN_2031 GBV_ILN_2044 GBV_ILN_2048 GBV_ILN_2050 GBV_ILN_2055 GBV_ILN_2056 GBV_ILN_2057 GBV_ILN_2061 GBV_ILN_2111 GBV_ILN_2190 GBV_ILN_4012 GBV_ILN_4037 GBV_ILN_4112 GBV_ILN_4125 GBV_ILN_4126 GBV_ILN_4249 GBV_ILN_4305 GBV_ILN_4306 GBV_ILN_4307 GBV_ILN_4313 GBV_ILN_4322 GBV_ILN_4323 GBV_ILN_4324 GBV_ILN_4325 GBV_ILN_4338 GBV_ILN_4367 GBV_ILN_4700 AR 14 2024 2, p 266
allfieldsGer	10.3390/ani14020266 doi (DE-627)DOAJ096398264 (DE-599)DOAJ3e69c1ec7944422b8802c07adbcd6f18 DE-627 ger DE-627 rakwb eng SF600-1100 QL1-991 Zihui Liu verfasserin aut Non-Additive and Asymmetric Allelic Expression of <i<p38 mapk</i< in Hybrid Tilapia (<i<Oreochromis niloticus</i< ♀ × <i<O. aureus</i< ♂) 2024 Text txt rdacontent Computermedien c rdamedia Online-Ressource cr rdacarrier Hybridization is a widely used breeding technique in fish species that enhances desirable traits in cultured species through heterosis. However, the mechanism by which hybrids alter gene expression to form heterosis remains unclear. In this study, a group of hybrid tilapia was used to elucidate heterosis through interspecies crossing. Specifically, <i<p38</i< was analyzed to describe the regulation of gene expression variation in hybrid tilapia. Transcripts from the Nile tilapia allele were found to be significantly higher than those from the blue tilapia allele in hybrid individuals, indicating that the expression of <i<p38</i< was dominated by Nile tilapia sub-genomic alleles. The study also found a compensatory interaction of cis- and trans-acting elements of the Nile tilapia and blue tilapia sub-genomes, inducing a non-additive expression of <i<p38</i< in hybrids. Eight specific SNPs were identified in the <i<p38</i< promoter regions of Nile tilapia and blue tilapia, and were found to be promoter differences leading to differences in gene expression efficiencies between parental alleles using a dual-luciferase reporter system. This study provides insights into the non-additive expression patterns of key functional genes in fish hybrids related to growth and immunity response. hybridization non-additive asymmetric allelic expression cis- and trans-acting elements <i<p38 mapk</i< Veterinary medicine Zoology Binglin Chen verfasserin aut Zhiying Zou verfasserin aut Dayu Li verfasserin aut Jinglin Zhu verfasserin aut Jie Yu verfasserin aut Wei Xiao verfasserin aut Hong Yang verfasserin aut In Animals MDPI AG, 2011 14(2024), 2, p 266 (DE-627)657589306 (DE-600)2606558-7 20762615 nnns volume:14 year:2024 number:2, p 266 https://doi.org/10.3390/ani14020266 kostenfrei https://doaj.org/article/3e69c1ec7944422b8802c07adbcd6f18 kostenfrei https://www.mdpi.com/2076-2615/14/2/266 kostenfrei https://doaj.org/toc/2076-2615 Journal toc kostenfrei GBV_USEFLAG_A SYSFLAG_A GBV_DOAJ GBV_ILN_20 GBV_ILN_22 GBV_ILN_23 GBV_ILN_24 GBV_ILN_39 GBV_ILN_40 GBV_ILN_60 GBV_ILN_62 GBV_ILN_63 GBV_ILN_65 GBV_ILN_69 GBV_ILN_73 GBV_ILN_95 GBV_ILN_105 GBV_ILN_110 GBV_ILN_151 GBV_ILN_161 GBV_ILN_206 GBV_ILN_213 GBV_ILN_230 GBV_ILN_285 GBV_ILN_293 GBV_ILN_602 GBV_ILN_702 GBV_ILN_2001 GBV_ILN_2003 GBV_ILN_2005 GBV_ILN_2006 GBV_ILN_2008 GBV_ILN_2009 GBV_ILN_2010 GBV_ILN_2011 GBV_ILN_2014 GBV_ILN_2015 GBV_ILN_2020 GBV_ILN_2021 GBV_ILN_2025 GBV_ILN_2031 GBV_ILN_2044 GBV_ILN_2048 GBV_ILN_2050 GBV_ILN_2055 GBV_ILN_2056 GBV_ILN_2057 GBV_ILN_2061 GBV_ILN_2111 GBV_ILN_2190 GBV_ILN_4012 GBV_ILN_4037 GBV_ILN_4112 GBV_ILN_4125 GBV_ILN_4126 GBV_ILN_4249 GBV_ILN_4305 GBV_ILN_4306 GBV_ILN_4307 GBV_ILN_4313 GBV_ILN_4322 GBV_ILN_4323 GBV_ILN_4324 GBV_ILN_4325 GBV_ILN_4338 GBV_ILN_4367 GBV_ILN_4700 AR 14 2024 2, p 266
allfieldsSound	10.3390/ani14020266 doi (DE-627)DOAJ096398264 (DE-599)DOAJ3e69c1ec7944422b8802c07adbcd6f18 DE-627 ger DE-627 rakwb eng SF600-1100 QL1-991 Zihui Liu verfasserin aut Non-Additive and Asymmetric Allelic Expression of <i<p38 mapk</i< in Hybrid Tilapia (<i<Oreochromis niloticus</i< ♀ × <i<O. aureus</i< ♂) 2024 Text txt rdacontent Computermedien c rdamedia Online-Ressource cr rdacarrier Hybridization is a widely used breeding technique in fish species that enhances desirable traits in cultured species through heterosis. However, the mechanism by which hybrids alter gene expression to form heterosis remains unclear. In this study, a group of hybrid tilapia was used to elucidate heterosis through interspecies crossing. Specifically, <i<p38</i< was analyzed to describe the regulation of gene expression variation in hybrid tilapia. Transcripts from the Nile tilapia allele were found to be significantly higher than those from the blue tilapia allele in hybrid individuals, indicating that the expression of <i<p38</i< was dominated by Nile tilapia sub-genomic alleles. The study also found a compensatory interaction of cis- and trans-acting elements of the Nile tilapia and blue tilapia sub-genomes, inducing a non-additive expression of <i<p38</i< in hybrids. Eight specific SNPs were identified in the <i<p38</i< promoter regions of Nile tilapia and blue tilapia, and were found to be promoter differences leading to differences in gene expression efficiencies between parental alleles using a dual-luciferase reporter system. This study provides insights into the non-additive expression patterns of key functional genes in fish hybrids related to growth and immunity response. hybridization non-additive asymmetric allelic expression cis- and trans-acting elements <i<p38 mapk</i< Veterinary medicine Zoology Binglin Chen verfasserin aut Zhiying Zou verfasserin aut Dayu Li verfasserin aut Jinglin Zhu verfasserin aut Jie Yu verfasserin aut Wei Xiao verfasserin aut Hong Yang verfasserin aut In Animals MDPI AG, 2011 14(2024), 2, p 266 (DE-627)657589306 (DE-600)2606558-7 20762615 nnns volume:14 year:2024 number:2, p 266 https://doi.org/10.3390/ani14020266 kostenfrei https://doaj.org/article/3e69c1ec7944422b8802c07adbcd6f18 kostenfrei https://www.mdpi.com/2076-2615/14/2/266 kostenfrei https://doaj.org/toc/2076-2615 Journal toc kostenfrei GBV_USEFLAG_A SYSFLAG_A GBV_DOAJ GBV_ILN_20 GBV_ILN_22 GBV_ILN_23 GBV_ILN_24 GBV_ILN_39 GBV_ILN_40 GBV_ILN_60 GBV_ILN_62 GBV_ILN_63 GBV_ILN_65 GBV_ILN_69 GBV_ILN_73 GBV_ILN_95 GBV_ILN_105 GBV_ILN_110 GBV_ILN_151 GBV_ILN_161 GBV_ILN_206 GBV_ILN_213 GBV_ILN_230 GBV_ILN_285 GBV_ILN_293 GBV_ILN_602 GBV_ILN_702 GBV_ILN_2001 GBV_ILN_2003 GBV_ILN_2005 GBV_ILN_2006 GBV_ILN_2008 GBV_ILN_2009 GBV_ILN_2010 GBV_ILN_2011 GBV_ILN_2014 GBV_ILN_2015 GBV_ILN_2020 GBV_ILN_2021 GBV_ILN_2025 GBV_ILN_2031 GBV_ILN_2044 GBV_ILN_2048 GBV_ILN_2050 GBV_ILN_2055 GBV_ILN_2056 GBV_ILN_2057 GBV_ILN_2061 GBV_ILN_2111 GBV_ILN_2190 GBV_ILN_4012 GBV_ILN_4037 GBV_ILN_4112 GBV_ILN_4125 GBV_ILN_4126 GBV_ILN_4249 GBV_ILN_4305 GBV_ILN_4306 GBV_ILN_4307 GBV_ILN_4313 GBV_ILN_4322 GBV_ILN_4323 GBV_ILN_4324 GBV_ILN_4325 GBV_ILN_4338 GBV_ILN_4367 GBV_ILN_4700 AR 14 2024 2, p 266
language	English
source	In Animals 14(2024), 2, p 266 volume:14 year:2024 number:2, p 266
sourceStr	In Animals 14(2024), 2, p 266 volume:14 year:2024 number:2, p 266
format_phy_str_mv	Article
institution	findex.gbv.de
topic_facet	hybridization non-additive asymmetric allelic expression cis- and trans-acting elements <i<p38 mapk</i< Veterinary medicine Zoology
isfreeaccess_bool	true
container_title	Animals
authorswithroles_txt_mv	Zihui Liu @@aut@@ Binglin Chen @@aut@@ Zhiying Zou @@aut@@ Dayu Li @@aut@@ Jinglin Zhu @@aut@@ Jie Yu @@aut@@ Wei Xiao @@aut@@ Hong Yang @@aut@@
publishDateDaySort_date	2024-01-01T00:00:00Z
hierarchy_top_id	657589306
id	DOAJ096398264
language_de	englisch
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callnumber-first	S - Agriculture
author	Zihui Liu
spellingShingle	Zihui Liu misc SF600-1100 misc QL1-991 misc hybridization misc non-additive misc asymmetric allelic expression misc cis- and trans-acting elements misc <i<p38 mapk</i< misc Veterinary medicine misc Zoology Non-Additive and Asymmetric Allelic Expression of <i<p38 mapk</i< in Hybrid Tilapia (<i<Oreochromis niloticus</i< ♀ × <i<O. aureus</i< ♂)
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topic_title	SF600-1100 QL1-991 Non-Additive and Asymmetric Allelic Expression of <i<p38 mapk</i< in Hybrid Tilapia (<i<Oreochromis niloticus</i< ♀ × <i<O. aureus</i< ♂) hybridization non-additive asymmetric allelic expression cis- and trans-acting elements <i<p38 mapk</i<
topic	misc SF600-1100 misc QL1-991 misc hybridization misc non-additive misc asymmetric allelic expression misc cis- and trans-acting elements misc <i<p38 mapk</i< misc Veterinary medicine misc Zoology
topic_unstemmed	misc SF600-1100 misc QL1-991 misc hybridization misc non-additive misc asymmetric allelic expression misc cis- and trans-acting elements misc <i<p38 mapk</i< misc Veterinary medicine misc Zoology
topic_browse	misc SF600-1100 misc QL1-991 misc hybridization misc non-additive misc asymmetric allelic expression misc cis- and trans-acting elements misc <i<p38 mapk</i< misc Veterinary medicine misc Zoology
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title	Non-Additive and Asymmetric Allelic Expression of <i<p38 mapk</i< in Hybrid Tilapia (<i<Oreochromis niloticus</i< ♀ × <i<O. aureus</i< ♂)
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title_full	Non-Additive and Asymmetric Allelic Expression of <i<p38 mapk</i< in Hybrid Tilapia (<i<Oreochromis niloticus</i< ♀ × <i<O. aureus</i< ♂)
author_sort	Zihui Liu
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author_browse	Zihui Liu Binglin Chen Zhiying Zou Dayu Li Jinglin Zhu Jie Yu Wei Xiao Hong Yang
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author-letter	Zihui Liu
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title_sort	non-additive and asymmetric allelic expression of <i<p38 mapk</i< in hybrid tilapia (<i<oreochromis niloticus</i< ♀ × <i<o. aureus</i< ♂)
callnumber	SF600-1100
title_auth	Non-Additive and Asymmetric Allelic Expression of <i<p38 mapk</i< in Hybrid Tilapia (<i<Oreochromis niloticus</i< ♀ × <i<O. aureus</i< ♂)
abstract	Hybridization is a widely used breeding technique in fish species that enhances desirable traits in cultured species through heterosis. However, the mechanism by which hybrids alter gene expression to form heterosis remains unclear. In this study, a group of hybrid tilapia was used to elucidate heterosis through interspecies crossing. Specifically, <i<p38</i< was analyzed to describe the regulation of gene expression variation in hybrid tilapia. Transcripts from the Nile tilapia allele were found to be significantly higher than those from the blue tilapia allele in hybrid individuals, indicating that the expression of <i<p38</i< was dominated by Nile tilapia sub-genomic alleles. The study also found a compensatory interaction of cis- and trans-acting elements of the Nile tilapia and blue tilapia sub-genomes, inducing a non-additive expression of <i<p38</i< in hybrids. Eight specific SNPs were identified in the <i<p38</i< promoter regions of Nile tilapia and blue tilapia, and were found to be promoter differences leading to differences in gene expression efficiencies between parental alleles using a dual-luciferase reporter system. This study provides insights into the non-additive expression patterns of key functional genes in fish hybrids related to growth and immunity response.
abstractGer	Hybridization is a widely used breeding technique in fish species that enhances desirable traits in cultured species through heterosis. However, the mechanism by which hybrids alter gene expression to form heterosis remains unclear. In this study, a group of hybrid tilapia was used to elucidate heterosis through interspecies crossing. Specifically, <i<p38</i< was analyzed to describe the regulation of gene expression variation in hybrid tilapia. Transcripts from the Nile tilapia allele were found to be significantly higher than those from the blue tilapia allele in hybrid individuals, indicating that the expression of <i<p38</i< was dominated by Nile tilapia sub-genomic alleles. The study also found a compensatory interaction of cis- and trans-acting elements of the Nile tilapia and blue tilapia sub-genomes, inducing a non-additive expression of <i<p38</i< in hybrids. Eight specific SNPs were identified in the <i<p38</i< promoter regions of Nile tilapia and blue tilapia, and were found to be promoter differences leading to differences in gene expression efficiencies between parental alleles using a dual-luciferase reporter system. This study provides insights into the non-additive expression patterns of key functional genes in fish hybrids related to growth and immunity response.
abstract_unstemmed	Hybridization is a widely used breeding technique in fish species that enhances desirable traits in cultured species through heterosis. However, the mechanism by which hybrids alter gene expression to form heterosis remains unclear. In this study, a group of hybrid tilapia was used to elucidate heterosis through interspecies crossing. Specifically, <i<p38</i< was analyzed to describe the regulation of gene expression variation in hybrid tilapia. Transcripts from the Nile tilapia allele were found to be significantly higher than those from the blue tilapia allele in hybrid individuals, indicating that the expression of <i<p38</i< was dominated by Nile tilapia sub-genomic alleles. The study also found a compensatory interaction of cis- and trans-acting elements of the Nile tilapia and blue tilapia sub-genomes, inducing a non-additive expression of <i<p38</i< in hybrids. Eight specific SNPs were identified in the <i<p38</i< promoter regions of Nile tilapia and blue tilapia, and were found to be promoter differences leading to differences in gene expression efficiencies between parental alleles using a dual-luciferase reporter system. This study provides insights into the non-additive expression patterns of key functional genes in fish hybrids related to growth and immunity response.
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container_issue	2, p 266
title_short	Non-Additive and Asymmetric Allelic Expression of <i<p38 mapk</i< in Hybrid Tilapia (<i<Oreochromis niloticus</i< ♀ × <i<O. aureus</i< ♂)
url	https://doi.org/10.3390/ani14020266 https://doaj.org/article/3e69c1ec7944422b8802c07adbcd6f18 https://www.mdpi.com/2076-2615/14/2/266 https://doaj.org/toc/2076-2615
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up_date	2024-07-03T19:57:44.431Z
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Non-Additive and Asymmetric Allelic Expression of <i<p38 mapk</i< in Hybrid Tilapia (<i<Oreochromis niloticus</i< ♀ × <i<O. aureus</i< ♂)

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