Determination of Peak Oxygen Uptake in Patients with Acute Myocardial Infarction: The Role of Arterial Stiffness in Cardio–Vascular–Skeletal Muscle Coupling

The relationship between arterial stiffness and oxygen uptake (VO<sub<2</sub<) in patients with acute myocardial infarction (AMI) remains unclear. We aimed to investigate this relationship and factors contributing to VO<sub<2</sub< in patients with AMI. The role of arterial s...
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Autor*in:	Akihiro Ogawa [verfasserIn] Shinya Kanzaki [verfasserIn] Yuki Ikeda [verfasserIn] Masahiro Iwakawa [verfasserIn] Takahiro Nakagami [verfasserIn] Shuji Sato [verfasserIn] Hiroshi Mikamo [verfasserIn] Satoshi Kido [verfasserIn] Arata Nakajima [verfasserIn] Kazuhiro Shimizu [verfasserIn]

Format:	E-Artikel
Sprache:	Englisch

Erschienen:	2023

Schlagwörter:	cardio–ankle vascular index acute myocardial infarction VO cardio–vascular–skeletal muscle coupling

Übergeordnetes Werk:	In: Journal of Clinical Medicine - MDPI AG, 2013, 13(2023), 1, p 42
Übergeordnetes Werk:	volume:13 ; year:2023 ; number:1, p 42

Links:	Link aufrufen Link aufrufen Link aufrufen Journal toc

DOI / URN:	10.3390/jcm13010042

Katalog-ID:	DOAJ097790281

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520			\|a The relationship between arterial stiffness and oxygen uptake (VO<sub<2</sub<) in patients with acute myocardial infarction (AMI) remains unclear. We aimed to investigate this relationship and factors contributing to VO<sub<2</sub< in patients with AMI. The role of arterial stiffness in cardio–skeletal muscle coupling during exercise was then elucidated. Upon discharge, we measured exercise capacity using cardiopulmonary exercise testing (CPX), assessed arterial stiffness with the cardio–ankle vascular index (CAVI), and determined body composition to assess the skeletal muscle mass of 101 patients with AMI. Patients were categorized based on their CAVI scores into three groups: (i) normal (CAVI: ≤7.9), (ii) borderline (CAVI: 8.0–8.9), and (iii) abnormal (CAVI: ≥9.0). Subsequently, VO<sub<2</sub< was compared among these groups. The relationship between the CAVI and VO<sub<2 Peak</sub< during CPX and factors contributing to VO<sub<2 Peak</sub< were investigated. The abnormal CAVI group had a significantly lower VO<sub<2 Peak</sub< than the normal and borderline groups. The CAVI was associated with VO<sub<2 Peak</sub<. Furthermore, the CAVI was found to be a factor contributing to VO<sub<2 Peak</sub<. These findings suggest that arterial stiffness in tissue blood distribution and blood supply causes systemic exercise limits in patients with AMI. This suggests that arterial stiffness plays a significant role in cardio–vascular–skeletal muscle coupling.
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allfields	10.3390/jcm13010042 doi (DE-627)DOAJ097790281 (DE-599)DOAJ8c5589ee3978452a9a9c8c550f424994 DE-627 ger DE-627 rakwb eng Akihiro Ogawa verfasserin aut Determination of Peak Oxygen Uptake in Patients with Acute Myocardial Infarction: The Role of Arterial Stiffness in Cardio–Vascular–Skeletal Muscle Coupling 2023 Text txt rdacontent Computermedien c rdamedia Online-Ressource cr rdacarrier The relationship between arterial stiffness and oxygen uptake (VO<sub<2</sub<) in patients with acute myocardial infarction (AMI) remains unclear. We aimed to investigate this relationship and factors contributing to VO<sub<2</sub< in patients with AMI. The role of arterial stiffness in cardio–skeletal muscle coupling during exercise was then elucidated. Upon discharge, we measured exercise capacity using cardiopulmonary exercise testing (CPX), assessed arterial stiffness with the cardio–ankle vascular index (CAVI), and determined body composition to assess the skeletal muscle mass of 101 patients with AMI. Patients were categorized based on their CAVI scores into three groups: (i) normal (CAVI: ≤7.9), (ii) borderline (CAVI: 8.0–8.9), and (iii) abnormal (CAVI: ≥9.0). Subsequently, VO<sub<2</sub< was compared among these groups. The relationship between the CAVI and VO<sub<2 Peak</sub< during CPX and factors contributing to VO<sub<2 Peak</sub< were investigated. The abnormal CAVI group had a significantly lower VO<sub<2 Peak</sub< than the normal and borderline groups. The CAVI was associated with VO<sub<2 Peak</sub<. Furthermore, the CAVI was found to be a factor contributing to VO<sub<2 Peak</sub<. These findings suggest that arterial stiffness in tissue blood distribution and blood supply causes systemic exercise limits in patients with AMI. This suggests that arterial stiffness plays a significant role in cardio–vascular–skeletal muscle coupling. cardio–ankle vascular index acute myocardial infarction VO<sub<2 Peak</sub< cardio–vascular–skeletal muscle coupling Medicine R Shinya Kanzaki verfasserin aut Yuki Ikeda verfasserin aut Masahiro Iwakawa verfasserin aut Takahiro Nakagami verfasserin aut Shuji Sato verfasserin aut Hiroshi Mikamo verfasserin aut Satoshi Kido verfasserin aut Arata Nakajima verfasserin aut Kazuhiro Shimizu verfasserin aut In Journal of Clinical Medicine MDPI AG, 2013 13(2023), 1, p 42 (DE-627)718632478 (DE-600)2662592-1 20770383 nnns volume:13 year:2023 number:1, p 42 https://doi.org/10.3390/jcm13010042 kostenfrei https://doaj.org/article/8c5589ee3978452a9a9c8c550f424994 kostenfrei https://www.mdpi.com/2077-0383/13/1/42 kostenfrei https://doaj.org/toc/2077-0383 Journal toc kostenfrei GBV_USEFLAG_A SYSFLAG_A GBV_DOAJ GBV_ILN_20 GBV_ILN_22 GBV_ILN_23 GBV_ILN_24 GBV_ILN_39 GBV_ILN_40 GBV_ILN_60 GBV_ILN_62 GBV_ILN_63 GBV_ILN_65 GBV_ILN_69 GBV_ILN_73 GBV_ILN_74 GBV_ILN_95 GBV_ILN_105 GBV_ILN_110 GBV_ILN_151 GBV_ILN_161 GBV_ILN_170 GBV_ILN_206 GBV_ILN_213 GBV_ILN_230 GBV_ILN_285 GBV_ILN_293 GBV_ILN_602 GBV_ILN_2005 GBV_ILN_2009 GBV_ILN_2014 GBV_ILN_2055 GBV_ILN_2111 GBV_ILN_4012 GBV_ILN_4037 GBV_ILN_4112 GBV_ILN_4125 GBV_ILN_4126 GBV_ILN_4249 GBV_ILN_4305 GBV_ILN_4306 GBV_ILN_4307 GBV_ILN_4313 GBV_ILN_4322 GBV_ILN_4323 GBV_ILN_4324 GBV_ILN_4325 GBV_ILN_4338 GBV_ILN_4367 GBV_ILN_4700 AR 13 2023 1, p 42
spelling	10.3390/jcm13010042 doi (DE-627)DOAJ097790281 (DE-599)DOAJ8c5589ee3978452a9a9c8c550f424994 DE-627 ger DE-627 rakwb eng Akihiro Ogawa verfasserin aut Determination of Peak Oxygen Uptake in Patients with Acute Myocardial Infarction: The Role of Arterial Stiffness in Cardio–Vascular–Skeletal Muscle Coupling 2023 Text txt rdacontent Computermedien c rdamedia Online-Ressource cr rdacarrier The relationship between arterial stiffness and oxygen uptake (VO<sub<2</sub<) in patients with acute myocardial infarction (AMI) remains unclear. We aimed to investigate this relationship and factors contributing to VO<sub<2</sub< in patients with AMI. The role of arterial stiffness in cardio–skeletal muscle coupling during exercise was then elucidated. Upon discharge, we measured exercise capacity using cardiopulmonary exercise testing (CPX), assessed arterial stiffness with the cardio–ankle vascular index (CAVI), and determined body composition to assess the skeletal muscle mass of 101 patients with AMI. Patients were categorized based on their CAVI scores into three groups: (i) normal (CAVI: ≤7.9), (ii) borderline (CAVI: 8.0–8.9), and (iii) abnormal (CAVI: ≥9.0). Subsequently, VO<sub<2</sub< was compared among these groups. The relationship between the CAVI and VO<sub<2 Peak</sub< during CPX and factors contributing to VO<sub<2 Peak</sub< were investigated. The abnormal CAVI group had a significantly lower VO<sub<2 Peak</sub< than the normal and borderline groups. The CAVI was associated with VO<sub<2 Peak</sub<. Furthermore, the CAVI was found to be a factor contributing to VO<sub<2 Peak</sub<. These findings suggest that arterial stiffness in tissue blood distribution and blood supply causes systemic exercise limits in patients with AMI. This suggests that arterial stiffness plays a significant role in cardio–vascular–skeletal muscle coupling. cardio–ankle vascular index acute myocardial infarction VO<sub<2 Peak</sub< cardio–vascular–skeletal muscle coupling Medicine R Shinya Kanzaki verfasserin aut Yuki Ikeda verfasserin aut Masahiro Iwakawa verfasserin aut Takahiro Nakagami verfasserin aut Shuji Sato verfasserin aut Hiroshi Mikamo verfasserin aut Satoshi Kido verfasserin aut Arata Nakajima verfasserin aut Kazuhiro Shimizu verfasserin aut In Journal of Clinical Medicine MDPI AG, 2013 13(2023), 1, p 42 (DE-627)718632478 (DE-600)2662592-1 20770383 nnns volume:13 year:2023 number:1, p 42 https://doi.org/10.3390/jcm13010042 kostenfrei https://doaj.org/article/8c5589ee3978452a9a9c8c550f424994 kostenfrei https://www.mdpi.com/2077-0383/13/1/42 kostenfrei https://doaj.org/toc/2077-0383 Journal toc kostenfrei GBV_USEFLAG_A SYSFLAG_A GBV_DOAJ GBV_ILN_20 GBV_ILN_22 GBV_ILN_23 GBV_ILN_24 GBV_ILN_39 GBV_ILN_40 GBV_ILN_60 GBV_ILN_62 GBV_ILN_63 GBV_ILN_65 GBV_ILN_69 GBV_ILN_73 GBV_ILN_74 GBV_ILN_95 GBV_ILN_105 GBV_ILN_110 GBV_ILN_151 GBV_ILN_161 GBV_ILN_170 GBV_ILN_206 GBV_ILN_213 GBV_ILN_230 GBV_ILN_285 GBV_ILN_293 GBV_ILN_602 GBV_ILN_2005 GBV_ILN_2009 GBV_ILN_2014 GBV_ILN_2055 GBV_ILN_2111 GBV_ILN_4012 GBV_ILN_4037 GBV_ILN_4112 GBV_ILN_4125 GBV_ILN_4126 GBV_ILN_4249 GBV_ILN_4305 GBV_ILN_4306 GBV_ILN_4307 GBV_ILN_4313 GBV_ILN_4322 GBV_ILN_4323 GBV_ILN_4324 GBV_ILN_4325 GBV_ILN_4338 GBV_ILN_4367 GBV_ILN_4700 AR 13 2023 1, p 42
allfields_unstemmed	10.3390/jcm13010042 doi (DE-627)DOAJ097790281 (DE-599)DOAJ8c5589ee3978452a9a9c8c550f424994 DE-627 ger DE-627 rakwb eng Akihiro Ogawa verfasserin aut Determination of Peak Oxygen Uptake in Patients with Acute Myocardial Infarction: The Role of Arterial Stiffness in Cardio–Vascular–Skeletal Muscle Coupling 2023 Text txt rdacontent Computermedien c rdamedia Online-Ressource cr rdacarrier The relationship between arterial stiffness and oxygen uptake (VO<sub<2</sub<) in patients with acute myocardial infarction (AMI) remains unclear. We aimed to investigate this relationship and factors contributing to VO<sub<2</sub< in patients with AMI. The role of arterial stiffness in cardio–skeletal muscle coupling during exercise was then elucidated. Upon discharge, we measured exercise capacity using cardiopulmonary exercise testing (CPX), assessed arterial stiffness with the cardio–ankle vascular index (CAVI), and determined body composition to assess the skeletal muscle mass of 101 patients with AMI. Patients were categorized based on their CAVI scores into three groups: (i) normal (CAVI: ≤7.9), (ii) borderline (CAVI: 8.0–8.9), and (iii) abnormal (CAVI: ≥9.0). Subsequently, VO<sub<2</sub< was compared among these groups. The relationship between the CAVI and VO<sub<2 Peak</sub< during CPX and factors contributing to VO<sub<2 Peak</sub< were investigated. The abnormal CAVI group had a significantly lower VO<sub<2 Peak</sub< than the normal and borderline groups. The CAVI was associated with VO<sub<2 Peak</sub<. Furthermore, the CAVI was found to be a factor contributing to VO<sub<2 Peak</sub<. These findings suggest that arterial stiffness in tissue blood distribution and blood supply causes systemic exercise limits in patients with AMI. This suggests that arterial stiffness plays a significant role in cardio–vascular–skeletal muscle coupling. cardio–ankle vascular index acute myocardial infarction VO<sub<2 Peak</sub< cardio–vascular–skeletal muscle coupling Medicine R Shinya Kanzaki verfasserin aut Yuki Ikeda verfasserin aut Masahiro Iwakawa verfasserin aut Takahiro Nakagami verfasserin aut Shuji Sato verfasserin aut Hiroshi Mikamo verfasserin aut Satoshi Kido verfasserin aut Arata Nakajima verfasserin aut Kazuhiro Shimizu verfasserin aut In Journal of Clinical Medicine MDPI AG, 2013 13(2023), 1, p 42 (DE-627)718632478 (DE-600)2662592-1 20770383 nnns volume:13 year:2023 number:1, p 42 https://doi.org/10.3390/jcm13010042 kostenfrei https://doaj.org/article/8c5589ee3978452a9a9c8c550f424994 kostenfrei https://www.mdpi.com/2077-0383/13/1/42 kostenfrei https://doaj.org/toc/2077-0383 Journal toc kostenfrei GBV_USEFLAG_A SYSFLAG_A GBV_DOAJ GBV_ILN_20 GBV_ILN_22 GBV_ILN_23 GBV_ILN_24 GBV_ILN_39 GBV_ILN_40 GBV_ILN_60 GBV_ILN_62 GBV_ILN_63 GBV_ILN_65 GBV_ILN_69 GBV_ILN_73 GBV_ILN_74 GBV_ILN_95 GBV_ILN_105 GBV_ILN_110 GBV_ILN_151 GBV_ILN_161 GBV_ILN_170 GBV_ILN_206 GBV_ILN_213 GBV_ILN_230 GBV_ILN_285 GBV_ILN_293 GBV_ILN_602 GBV_ILN_2005 GBV_ILN_2009 GBV_ILN_2014 GBV_ILN_2055 GBV_ILN_2111 GBV_ILN_4012 GBV_ILN_4037 GBV_ILN_4112 GBV_ILN_4125 GBV_ILN_4126 GBV_ILN_4249 GBV_ILN_4305 GBV_ILN_4306 GBV_ILN_4307 GBV_ILN_4313 GBV_ILN_4322 GBV_ILN_4323 GBV_ILN_4324 GBV_ILN_4325 GBV_ILN_4338 GBV_ILN_4367 GBV_ILN_4700 AR 13 2023 1, p 42
allfieldsGer	10.3390/jcm13010042 doi (DE-627)DOAJ097790281 (DE-599)DOAJ8c5589ee3978452a9a9c8c550f424994 DE-627 ger DE-627 rakwb eng Akihiro Ogawa verfasserin aut Determination of Peak Oxygen Uptake in Patients with Acute Myocardial Infarction: The Role of Arterial Stiffness in Cardio–Vascular–Skeletal Muscle Coupling 2023 Text txt rdacontent Computermedien c rdamedia Online-Ressource cr rdacarrier The relationship between arterial stiffness and oxygen uptake (VO<sub<2</sub<) in patients with acute myocardial infarction (AMI) remains unclear. We aimed to investigate this relationship and factors contributing to VO<sub<2</sub< in patients with AMI. The role of arterial stiffness in cardio–skeletal muscle coupling during exercise was then elucidated. Upon discharge, we measured exercise capacity using cardiopulmonary exercise testing (CPX), assessed arterial stiffness with the cardio–ankle vascular index (CAVI), and determined body composition to assess the skeletal muscle mass of 101 patients with AMI. Patients were categorized based on their CAVI scores into three groups: (i) normal (CAVI: ≤7.9), (ii) borderline (CAVI: 8.0–8.9), and (iii) abnormal (CAVI: ≥9.0). Subsequently, VO<sub<2</sub< was compared among these groups. The relationship between the CAVI and VO<sub<2 Peak</sub< during CPX and factors contributing to VO<sub<2 Peak</sub< were investigated. The abnormal CAVI group had a significantly lower VO<sub<2 Peak</sub< than the normal and borderline groups. The CAVI was associated with VO<sub<2 Peak</sub<. Furthermore, the CAVI was found to be a factor contributing to VO<sub<2 Peak</sub<. These findings suggest that arterial stiffness in tissue blood distribution and blood supply causes systemic exercise limits in patients with AMI. This suggests that arterial stiffness plays a significant role in cardio–vascular–skeletal muscle coupling. cardio–ankle vascular index acute myocardial infarction VO<sub<2 Peak</sub< cardio–vascular–skeletal muscle coupling Medicine R Shinya Kanzaki verfasserin aut Yuki Ikeda verfasserin aut Masahiro Iwakawa verfasserin aut Takahiro Nakagami verfasserin aut Shuji Sato verfasserin aut Hiroshi Mikamo verfasserin aut Satoshi Kido verfasserin aut Arata Nakajima verfasserin aut Kazuhiro Shimizu verfasserin aut In Journal of Clinical Medicine MDPI AG, 2013 13(2023), 1, p 42 (DE-627)718632478 (DE-600)2662592-1 20770383 nnns volume:13 year:2023 number:1, p 42 https://doi.org/10.3390/jcm13010042 kostenfrei https://doaj.org/article/8c5589ee3978452a9a9c8c550f424994 kostenfrei https://www.mdpi.com/2077-0383/13/1/42 kostenfrei https://doaj.org/toc/2077-0383 Journal toc kostenfrei GBV_USEFLAG_A SYSFLAG_A GBV_DOAJ GBV_ILN_20 GBV_ILN_22 GBV_ILN_23 GBV_ILN_24 GBV_ILN_39 GBV_ILN_40 GBV_ILN_60 GBV_ILN_62 GBV_ILN_63 GBV_ILN_65 GBV_ILN_69 GBV_ILN_73 GBV_ILN_74 GBV_ILN_95 GBV_ILN_105 GBV_ILN_110 GBV_ILN_151 GBV_ILN_161 GBV_ILN_170 GBV_ILN_206 GBV_ILN_213 GBV_ILN_230 GBV_ILN_285 GBV_ILN_293 GBV_ILN_602 GBV_ILN_2005 GBV_ILN_2009 GBV_ILN_2014 GBV_ILN_2055 GBV_ILN_2111 GBV_ILN_4012 GBV_ILN_4037 GBV_ILN_4112 GBV_ILN_4125 GBV_ILN_4126 GBV_ILN_4249 GBV_ILN_4305 GBV_ILN_4306 GBV_ILN_4307 GBV_ILN_4313 GBV_ILN_4322 GBV_ILN_4323 GBV_ILN_4324 GBV_ILN_4325 GBV_ILN_4338 GBV_ILN_4367 GBV_ILN_4700 AR 13 2023 1, p 42
allfieldsSound	10.3390/jcm13010042 doi (DE-627)DOAJ097790281 (DE-599)DOAJ8c5589ee3978452a9a9c8c550f424994 DE-627 ger DE-627 rakwb eng Akihiro Ogawa verfasserin aut Determination of Peak Oxygen Uptake in Patients with Acute Myocardial Infarction: The Role of Arterial Stiffness in Cardio–Vascular–Skeletal Muscle Coupling 2023 Text txt rdacontent Computermedien c rdamedia Online-Ressource cr rdacarrier The relationship between arterial stiffness and oxygen uptake (VO<sub<2</sub<) in patients with acute myocardial infarction (AMI) remains unclear. We aimed to investigate this relationship and factors contributing to VO<sub<2</sub< in patients with AMI. The role of arterial stiffness in cardio–skeletal muscle coupling during exercise was then elucidated. Upon discharge, we measured exercise capacity using cardiopulmonary exercise testing (CPX), assessed arterial stiffness with the cardio–ankle vascular index (CAVI), and determined body composition to assess the skeletal muscle mass of 101 patients with AMI. Patients were categorized based on their CAVI scores into three groups: (i) normal (CAVI: ≤7.9), (ii) borderline (CAVI: 8.0–8.9), and (iii) abnormal (CAVI: ≥9.0). Subsequently, VO<sub<2</sub< was compared among these groups. The relationship between the CAVI and VO<sub<2 Peak</sub< during CPX and factors contributing to VO<sub<2 Peak</sub< were investigated. The abnormal CAVI group had a significantly lower VO<sub<2 Peak</sub< than the normal and borderline groups. The CAVI was associated with VO<sub<2 Peak</sub<. Furthermore, the CAVI was found to be a factor contributing to VO<sub<2 Peak</sub<. These findings suggest that arterial stiffness in tissue blood distribution and blood supply causes systemic exercise limits in patients with AMI. This suggests that arterial stiffness plays a significant role in cardio–vascular–skeletal muscle coupling. cardio–ankle vascular index acute myocardial infarction VO<sub<2 Peak</sub< cardio–vascular–skeletal muscle coupling Medicine R Shinya Kanzaki verfasserin aut Yuki Ikeda verfasserin aut Masahiro Iwakawa verfasserin aut Takahiro Nakagami verfasserin aut Shuji Sato verfasserin aut Hiroshi Mikamo verfasserin aut Satoshi Kido verfasserin aut Arata Nakajima verfasserin aut Kazuhiro Shimizu verfasserin aut In Journal of Clinical Medicine MDPI AG, 2013 13(2023), 1, p 42 (DE-627)718632478 (DE-600)2662592-1 20770383 nnns volume:13 year:2023 number:1, p 42 https://doi.org/10.3390/jcm13010042 kostenfrei https://doaj.org/article/8c5589ee3978452a9a9c8c550f424994 kostenfrei https://www.mdpi.com/2077-0383/13/1/42 kostenfrei https://doaj.org/toc/2077-0383 Journal toc kostenfrei GBV_USEFLAG_A SYSFLAG_A GBV_DOAJ GBV_ILN_20 GBV_ILN_22 GBV_ILN_23 GBV_ILN_24 GBV_ILN_39 GBV_ILN_40 GBV_ILN_60 GBV_ILN_62 GBV_ILN_63 GBV_ILN_65 GBV_ILN_69 GBV_ILN_73 GBV_ILN_74 GBV_ILN_95 GBV_ILN_105 GBV_ILN_110 GBV_ILN_151 GBV_ILN_161 GBV_ILN_170 GBV_ILN_206 GBV_ILN_213 GBV_ILN_230 GBV_ILN_285 GBV_ILN_293 GBV_ILN_602 GBV_ILN_2005 GBV_ILN_2009 GBV_ILN_2014 GBV_ILN_2055 GBV_ILN_2111 GBV_ILN_4012 GBV_ILN_4037 GBV_ILN_4112 GBV_ILN_4125 GBV_ILN_4126 GBV_ILN_4249 GBV_ILN_4305 GBV_ILN_4306 GBV_ILN_4307 GBV_ILN_4313 GBV_ILN_4322 GBV_ILN_4323 GBV_ILN_4324 GBV_ILN_4325 GBV_ILN_4338 GBV_ILN_4367 GBV_ILN_4700 AR 13 2023 1, p 42
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author	Akihiro Ogawa
spellingShingle	Akihiro Ogawa misc cardio–ankle vascular index misc acute myocardial infarction misc VO<sub<2 Peak</sub< misc cardio–vascular–skeletal muscle coupling misc Medicine misc R Determination of Peak Oxygen Uptake in Patients with Acute Myocardial Infarction: The Role of Arterial Stiffness in Cardio–Vascular–Skeletal Muscle Coupling
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topic_title	Determination of Peak Oxygen Uptake in Patients with Acute Myocardial Infarction: The Role of Arterial Stiffness in Cardio–Vascular–Skeletal Muscle Coupling cardio–ankle vascular index acute myocardial infarction VO<sub<2 Peak</sub< cardio–vascular–skeletal muscle coupling
topic	misc cardio–ankle vascular index misc acute myocardial infarction misc VO<sub<2 Peak</sub< misc cardio–vascular–skeletal muscle coupling misc Medicine misc R
topic_unstemmed	misc cardio–ankle vascular index misc acute myocardial infarction misc VO<sub<2 Peak</sub< misc cardio–vascular–skeletal muscle coupling misc Medicine misc R
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title	Determination of Peak Oxygen Uptake in Patients with Acute Myocardial Infarction: The Role of Arterial Stiffness in Cardio–Vascular–Skeletal Muscle Coupling
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title_full	Determination of Peak Oxygen Uptake in Patients with Acute Myocardial Infarction: The Role of Arterial Stiffness in Cardio–Vascular–Skeletal Muscle Coupling
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title_sort	determination of peak oxygen uptake in patients with acute myocardial infarction: the role of arterial stiffness in cardio–vascular–skeletal muscle coupling
title_auth	Determination of Peak Oxygen Uptake in Patients with Acute Myocardial Infarction: The Role of Arterial Stiffness in Cardio–Vascular–Skeletal Muscle Coupling
abstract	The relationship between arterial stiffness and oxygen uptake (VO<sub<2</sub<) in patients with acute myocardial infarction (AMI) remains unclear. We aimed to investigate this relationship and factors contributing to VO<sub<2</sub< in patients with AMI. The role of arterial stiffness in cardio–skeletal muscle coupling during exercise was then elucidated. Upon discharge, we measured exercise capacity using cardiopulmonary exercise testing (CPX), assessed arterial stiffness with the cardio–ankle vascular index (CAVI), and determined body composition to assess the skeletal muscle mass of 101 patients with AMI. Patients were categorized based on their CAVI scores into three groups: (i) normal (CAVI: ≤7.9), (ii) borderline (CAVI: 8.0–8.9), and (iii) abnormal (CAVI: ≥9.0). Subsequently, VO<sub<2</sub< was compared among these groups. The relationship between the CAVI and VO<sub<2 Peak</sub< during CPX and factors contributing to VO<sub<2 Peak</sub< were investigated. The abnormal CAVI group had a significantly lower VO<sub<2 Peak</sub< than the normal and borderline groups. The CAVI was associated with VO<sub<2 Peak</sub<. Furthermore, the CAVI was found to be a factor contributing to VO<sub<2 Peak</sub<. These findings suggest that arterial stiffness in tissue blood distribution and blood supply causes systemic exercise limits in patients with AMI. This suggests that arterial stiffness plays a significant role in cardio–vascular–skeletal muscle coupling.
abstractGer	The relationship between arterial stiffness and oxygen uptake (VO<sub<2</sub<) in patients with acute myocardial infarction (AMI) remains unclear. We aimed to investigate this relationship and factors contributing to VO<sub<2</sub< in patients with AMI. The role of arterial stiffness in cardio–skeletal muscle coupling during exercise was then elucidated. Upon discharge, we measured exercise capacity using cardiopulmonary exercise testing (CPX), assessed arterial stiffness with the cardio–ankle vascular index (CAVI), and determined body composition to assess the skeletal muscle mass of 101 patients with AMI. Patients were categorized based on their CAVI scores into three groups: (i) normal (CAVI: ≤7.9), (ii) borderline (CAVI: 8.0–8.9), and (iii) abnormal (CAVI: ≥9.0). Subsequently, VO<sub<2</sub< was compared among these groups. The relationship between the CAVI and VO<sub<2 Peak</sub< during CPX and factors contributing to VO<sub<2 Peak</sub< were investigated. The abnormal CAVI group had a significantly lower VO<sub<2 Peak</sub< than the normal and borderline groups. The CAVI was associated with VO<sub<2 Peak</sub<. Furthermore, the CAVI was found to be a factor contributing to VO<sub<2 Peak</sub<. These findings suggest that arterial stiffness in tissue blood distribution and blood supply causes systemic exercise limits in patients with AMI. This suggests that arterial stiffness plays a significant role in cardio–vascular–skeletal muscle coupling.
abstract_unstemmed	The relationship between arterial stiffness and oxygen uptake (VO<sub<2</sub<) in patients with acute myocardial infarction (AMI) remains unclear. We aimed to investigate this relationship and factors contributing to VO<sub<2</sub< in patients with AMI. The role of arterial stiffness in cardio–skeletal muscle coupling during exercise was then elucidated. Upon discharge, we measured exercise capacity using cardiopulmonary exercise testing (CPX), assessed arterial stiffness with the cardio–ankle vascular index (CAVI), and determined body composition to assess the skeletal muscle mass of 101 patients with AMI. Patients were categorized based on their CAVI scores into three groups: (i) normal (CAVI: ≤7.9), (ii) borderline (CAVI: 8.0–8.9), and (iii) abnormal (CAVI: ≥9.0). Subsequently, VO<sub<2</sub< was compared among these groups. The relationship between the CAVI and VO<sub<2 Peak</sub< during CPX and factors contributing to VO<sub<2 Peak</sub< were investigated. The abnormal CAVI group had a significantly lower VO<sub<2 Peak</sub< than the normal and borderline groups. The CAVI was associated with VO<sub<2 Peak</sub<. Furthermore, the CAVI was found to be a factor contributing to VO<sub<2 Peak</sub<. These findings suggest that arterial stiffness in tissue blood distribution and blood supply causes systemic exercise limits in patients with AMI. This suggests that arterial stiffness plays a significant role in cardio–vascular–skeletal muscle coupling.
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title_short	Determination of Peak Oxygen Uptake in Patients with Acute Myocardial Infarction: The Role of Arterial Stiffness in Cardio–Vascular–Skeletal Muscle Coupling
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We aimed to investigate this relationship and factors contributing to VO<sub<2</sub< in patients with AMI. The role of arterial stiffness in cardio–skeletal muscle coupling during exercise was then elucidated. Upon discharge, we measured exercise capacity using cardiopulmonary exercise testing (CPX), assessed arterial stiffness with the cardio–ankle vascular index (CAVI), and determined body composition to assess the skeletal muscle mass of 101 patients with AMI. Patients were categorized based on their CAVI scores into three groups: (i) normal (CAVI: ≤7.9), (ii) borderline (CAVI: 8.0–8.9), and (iii) abnormal (CAVI: ≥9.0). Subsequently, VO<sub<2</sub< was compared among these groups. The relationship between the CAVI and VO<sub<2 Peak</sub< during CPX and factors contributing to VO<sub<2 Peak</sub< were investigated. The abnormal CAVI group had a significantly lower VO<sub<2 Peak</sub< than the normal and borderline groups. The CAVI was associated with VO<sub<2 Peak</sub<. Furthermore, the CAVI was found to be a factor contributing to VO<sub<2 Peak</sub<. These findings suggest that arterial stiffness in tissue blood distribution and blood supply causes systemic exercise limits in patients with AMI. 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Determination of Peak Oxygen Uptake in Patients with Acute Myocardial Infarction: The Role of Arterial Stiffness in Cardio–Vascular–Skeletal Muscle Coupling

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