Factors associated with the outcome of patients with COVID‐19 requiring mechanical ventilation: A single‐center observational study in Japan
Abstract Aim Coronavirus disease (COVID‐19) spread worldwide, and was declared as a pandemic by the World Health Organization. Despite numerous studies in the last few years, the factors associated with the outcomes of patients with COVID‐19 requiring mechanical ventilation remain unclear. The predi...
Ausführliche Beschreibung
Gespeichert in:
| Autor*in: |
Ryo Deguchi [verfasserIn] Tetsuro Nishimura [verfasserIn] Kenji Matsuo [verfasserIn] Fumiaki Wakita [verfasserIn] Akihiro Kawamoto [verfasserIn] Kenichiro Uchida [verfasserIn] Hiromasa Yamamoto [verfasserIn] Koichi Yamada [verfasserIn] Hiroshi Kakeya [verfasserIn] Hiromichi Fujii [verfasserIn] Toshihiko Shibata [verfasserIn] Yasumitsu Mizobata [verfasserIn] |
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| Format: |
E-Artikel |
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| Sprache: |
Englisch |
| Erschienen: |
2023 |
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| Schlagwörter: |
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| Übergeordnetes Werk: |
In: Acute Medicine & Surgery - Wiley, 2018, 10(2023), 1, Seite n/a-n/a |
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| Übergeordnetes Werk: |
volume:10 ; year:2023 ; number:1 ; pages:n/a-n/a |
| Links: |
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| DOI / URN: |
10.1002/ams2.868 |
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| Katalog-ID: |
DOAJ098063073 |
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| 520 | |a Abstract Aim Coronavirus disease (COVID‐19) spread worldwide, and was declared as a pandemic by the World Health Organization. Despite numerous studies in the last few years, the factors associated with the outcomes of patients with COVID‐19 requiring mechanical ventilation remain unclear. The prediction of ventilator weaning and mortality using the data obtained at the time of intubation could be beneficial for establishing appropriate treatment strategies and obtaining informed consent. In this study, we aimed to clarify the association between patient information at the time of intubation and the outcomes of intubated COVID‐19 patients. Methods This retrospective observational study used single‐center data from patients with COVID‐19. Patients with COVID‐19 who were admitted to Osaka Metropolitan University Hospital from April 1, 2020, to March 31, 2022, and under mechanical ventilation were included. The main outcome was defined as the factors related to ventilator weaning; a multivariate analysis was carried out to evaluate the association between patient information at the time of intubation and the outcome. Results In total, 146 patients were included in this study. The factors significantly associated with ventilator weaning were age (65–74 years old, adjusted odds ratio [OR], 0.168; 75 years and older, adjusted OR, 0.121), vaccination history (adjusted OR, 5.655), and Sequential Organ Failure Assessment (SOFA) respiration score (adjusted OR, 0.007) at the time of intubation. Conclusion Age, SOFA respiration score, and COVID‐19 vaccination history at the time of intubation could be associated with outcomes in patients with COVID‐19 requiring mechanical ventilation. | ||
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| 650 | 4 | |a prognostic factor | |
| 650 | 4 | |a ventilator weaning | |
| 653 | 0 | |a Medical emergencies. Critical care. Intensive care. First aid | |
| 700 | 0 | |a Tetsuro Nishimura |e verfasserin |4 aut | |
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| 700 | 0 | |a Kenichiro Uchida |e verfasserin |4 aut | |
| 700 | 0 | |a Hiromasa Yamamoto |e verfasserin |4 aut | |
| 700 | 0 | |a Koichi Yamada |e verfasserin |4 aut | |
| 700 | 0 | |a Hiroshi Kakeya |e verfasserin |4 aut | |
| 700 | 0 | |a Hiromichi Fujii |e verfasserin |4 aut | |
| 700 | 0 | |a Toshihiko Shibata |e verfasserin |4 aut | |
| 700 | 0 | |a Yasumitsu Mizobata |e verfasserin |4 aut | |
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10.1002/ams2.868 doi (DE-627)DOAJ098063073 (DE-599)DOAJ7b8eb458017f44858ddfc7d7c03b2c8f DE-627 ger DE-627 rakwb eng RC86-88.9 Ryo Deguchi verfasserin aut Factors associated with the outcome of patients with COVID‐19 requiring mechanical ventilation: A single‐center observational study in Japan 2023 Text txt rdacontent Computermedien c rdamedia Online-Ressource cr rdacarrier Abstract Aim Coronavirus disease (COVID‐19) spread worldwide, and was declared as a pandemic by the World Health Organization. Despite numerous studies in the last few years, the factors associated with the outcomes of patients with COVID‐19 requiring mechanical ventilation remain unclear. The prediction of ventilator weaning and mortality using the data obtained at the time of intubation could be beneficial for establishing appropriate treatment strategies and obtaining informed consent. In this study, we aimed to clarify the association between patient information at the time of intubation and the outcomes of intubated COVID‐19 patients. Methods This retrospective observational study used single‐center data from patients with COVID‐19. Patients with COVID‐19 who were admitted to Osaka Metropolitan University Hospital from April 1, 2020, to March 31, 2022, and under mechanical ventilation were included. The main outcome was defined as the factors related to ventilator weaning; a multivariate analysis was carried out to evaluate the association between patient information at the time of intubation and the outcome. Results In total, 146 patients were included in this study. The factors significantly associated with ventilator weaning were age (65–74 years old, adjusted odds ratio [OR], 0.168; 75 years and older, adjusted OR, 0.121), vaccination history (adjusted OR, 5.655), and Sequential Organ Failure Assessment (SOFA) respiration score (adjusted OR, 0.007) at the time of intubation. Conclusion Age, SOFA respiration score, and COVID‐19 vaccination history at the time of intubation could be associated with outcomes in patients with COVID‐19 requiring mechanical ventilation. COVID‐19 mechanical ventilation prognostic factor ventilator weaning Medical emergencies. Critical care. Intensive care. First aid Tetsuro Nishimura verfasserin aut Kenji Matsuo verfasserin aut Fumiaki Wakita verfasserin aut Akihiro Kawamoto verfasserin aut Kenichiro Uchida verfasserin aut Hiromasa Yamamoto verfasserin aut Koichi Yamada verfasserin aut Hiroshi Kakeya verfasserin aut Hiromichi Fujii verfasserin aut Toshihiko Shibata verfasserin aut Yasumitsu Mizobata verfasserin aut In Acute Medicine & Surgery Wiley, 2018 10(2023), 1, Seite n/a-n/a (DE-627)776855808 (DE-600)2751184-4 20528817 nnns volume:10 year:2023 number:1 pages:n/a-n/a https://doi.org/10.1002/ams2.868 kostenfrei https://doaj.org/article/7b8eb458017f44858ddfc7d7c03b2c8f kostenfrei https://doi.org/10.1002/ams2.868 kostenfrei https://doaj.org/toc/2052-8817 Journal toc kostenfrei GBV_USEFLAG_A SYSFLAG_A GBV_DOAJ GBV_ILN_20 GBV_ILN_22 GBV_ILN_23 GBV_ILN_24 GBV_ILN_31 GBV_ILN_39 GBV_ILN_40 GBV_ILN_60 GBV_ILN_62 GBV_ILN_63 GBV_ILN_65 GBV_ILN_69 GBV_ILN_73 GBV_ILN_74 GBV_ILN_95 GBV_ILN_105 GBV_ILN_110 GBV_ILN_151 GBV_ILN_161 GBV_ILN_170 GBV_ILN_171 GBV_ILN_206 GBV_ILN_213 GBV_ILN_224 GBV_ILN_230 GBV_ILN_285 GBV_ILN_293 GBV_ILN_602 GBV_ILN_636 GBV_ILN_2004 GBV_ILN_2005 GBV_ILN_2006 GBV_ILN_2007 GBV_ILN_2010 GBV_ILN_2011 GBV_ILN_2014 GBV_ILN_2026 GBV_ILN_2027 GBV_ILN_2034 GBV_ILN_2037 GBV_ILN_2038 GBV_ILN_2044 GBV_ILN_2048 GBV_ILN_2049 GBV_ILN_2050 GBV_ILN_2055 GBV_ILN_2056 GBV_ILN_2057 GBV_ILN_2059 GBV_ILN_2061 GBV_ILN_2064 GBV_ILN_2068 GBV_ILN_2088 GBV_ILN_2106 GBV_ILN_2108 GBV_ILN_2110 GBV_ILN_2111 GBV_ILN_2118 GBV_ILN_2122 GBV_ILN_2143 GBV_ILN_2144 GBV_ILN_2147 GBV_ILN_2148 GBV_ILN_2152 GBV_ILN_2153 GBV_ILN_2232 GBV_ILN_2336 GBV_ILN_2470 GBV_ILN_2507 GBV_ILN_2522 GBV_ILN_4012 GBV_ILN_4035 GBV_ILN_4037 GBV_ILN_4046 GBV_ILN_4112 GBV_ILN_4125 GBV_ILN_4126 GBV_ILN_4242 GBV_ILN_4249 GBV_ILN_4251 GBV_ILN_4305 GBV_ILN_4306 GBV_ILN_4307 GBV_ILN_4313 GBV_ILN_4322 GBV_ILN_4323 GBV_ILN_4324 GBV_ILN_4325 GBV_ILN_4326 GBV_ILN_4333 GBV_ILN_4334 GBV_ILN_4335 GBV_ILN_4336 GBV_ILN_4338 GBV_ILN_4367 GBV_ILN_4700 AR 10 2023 1 n/a-n/a |
| spelling |
10.1002/ams2.868 doi (DE-627)DOAJ098063073 (DE-599)DOAJ7b8eb458017f44858ddfc7d7c03b2c8f DE-627 ger DE-627 rakwb eng RC86-88.9 Ryo Deguchi verfasserin aut Factors associated with the outcome of patients with COVID‐19 requiring mechanical ventilation: A single‐center observational study in Japan 2023 Text txt rdacontent Computermedien c rdamedia Online-Ressource cr rdacarrier Abstract Aim Coronavirus disease (COVID‐19) spread worldwide, and was declared as a pandemic by the World Health Organization. Despite numerous studies in the last few years, the factors associated with the outcomes of patients with COVID‐19 requiring mechanical ventilation remain unclear. The prediction of ventilator weaning and mortality using the data obtained at the time of intubation could be beneficial for establishing appropriate treatment strategies and obtaining informed consent. In this study, we aimed to clarify the association between patient information at the time of intubation and the outcomes of intubated COVID‐19 patients. Methods This retrospective observational study used single‐center data from patients with COVID‐19. Patients with COVID‐19 who were admitted to Osaka Metropolitan University Hospital from April 1, 2020, to March 31, 2022, and under mechanical ventilation were included. The main outcome was defined as the factors related to ventilator weaning; a multivariate analysis was carried out to evaluate the association between patient information at the time of intubation and the outcome. Results In total, 146 patients were included in this study. The factors significantly associated with ventilator weaning were age (65–74 years old, adjusted odds ratio [OR], 0.168; 75 years and older, adjusted OR, 0.121), vaccination history (adjusted OR, 5.655), and Sequential Organ Failure Assessment (SOFA) respiration score (adjusted OR, 0.007) at the time of intubation. Conclusion Age, SOFA respiration score, and COVID‐19 vaccination history at the time of intubation could be associated with outcomes in patients with COVID‐19 requiring mechanical ventilation. COVID‐19 mechanical ventilation prognostic factor ventilator weaning Medical emergencies. Critical care. Intensive care. First aid Tetsuro Nishimura verfasserin aut Kenji Matsuo verfasserin aut Fumiaki Wakita verfasserin aut Akihiro Kawamoto verfasserin aut Kenichiro Uchida verfasserin aut Hiromasa Yamamoto verfasserin aut Koichi Yamada verfasserin aut Hiroshi Kakeya verfasserin aut Hiromichi Fujii verfasserin aut Toshihiko Shibata verfasserin aut Yasumitsu Mizobata verfasserin aut In Acute Medicine & Surgery Wiley, 2018 10(2023), 1, Seite n/a-n/a (DE-627)776855808 (DE-600)2751184-4 20528817 nnns volume:10 year:2023 number:1 pages:n/a-n/a https://doi.org/10.1002/ams2.868 kostenfrei https://doaj.org/article/7b8eb458017f44858ddfc7d7c03b2c8f kostenfrei https://doi.org/10.1002/ams2.868 kostenfrei https://doaj.org/toc/2052-8817 Journal toc kostenfrei GBV_USEFLAG_A SYSFLAG_A GBV_DOAJ GBV_ILN_20 GBV_ILN_22 GBV_ILN_23 GBV_ILN_24 GBV_ILN_31 GBV_ILN_39 GBV_ILN_40 GBV_ILN_60 GBV_ILN_62 GBV_ILN_63 GBV_ILN_65 GBV_ILN_69 GBV_ILN_73 GBV_ILN_74 GBV_ILN_95 GBV_ILN_105 GBV_ILN_110 GBV_ILN_151 GBV_ILN_161 GBV_ILN_170 GBV_ILN_171 GBV_ILN_206 GBV_ILN_213 GBV_ILN_224 GBV_ILN_230 GBV_ILN_285 GBV_ILN_293 GBV_ILN_602 GBV_ILN_636 GBV_ILN_2004 GBV_ILN_2005 GBV_ILN_2006 GBV_ILN_2007 GBV_ILN_2010 GBV_ILN_2011 GBV_ILN_2014 GBV_ILN_2026 GBV_ILN_2027 GBV_ILN_2034 GBV_ILN_2037 GBV_ILN_2038 GBV_ILN_2044 GBV_ILN_2048 GBV_ILN_2049 GBV_ILN_2050 GBV_ILN_2055 GBV_ILN_2056 GBV_ILN_2057 GBV_ILN_2059 GBV_ILN_2061 GBV_ILN_2064 GBV_ILN_2068 GBV_ILN_2088 GBV_ILN_2106 GBV_ILN_2108 GBV_ILN_2110 GBV_ILN_2111 GBV_ILN_2118 GBV_ILN_2122 GBV_ILN_2143 GBV_ILN_2144 GBV_ILN_2147 GBV_ILN_2148 GBV_ILN_2152 GBV_ILN_2153 GBV_ILN_2232 GBV_ILN_2336 GBV_ILN_2470 GBV_ILN_2507 GBV_ILN_2522 GBV_ILN_4012 GBV_ILN_4035 GBV_ILN_4037 GBV_ILN_4046 GBV_ILN_4112 GBV_ILN_4125 GBV_ILN_4126 GBV_ILN_4242 GBV_ILN_4249 GBV_ILN_4251 GBV_ILN_4305 GBV_ILN_4306 GBV_ILN_4307 GBV_ILN_4313 GBV_ILN_4322 GBV_ILN_4323 GBV_ILN_4324 GBV_ILN_4325 GBV_ILN_4326 GBV_ILN_4333 GBV_ILN_4334 GBV_ILN_4335 GBV_ILN_4336 GBV_ILN_4338 GBV_ILN_4367 GBV_ILN_4700 AR 10 2023 1 n/a-n/a |
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10.1002/ams2.868 doi (DE-627)DOAJ098063073 (DE-599)DOAJ7b8eb458017f44858ddfc7d7c03b2c8f DE-627 ger DE-627 rakwb eng RC86-88.9 Ryo Deguchi verfasserin aut Factors associated with the outcome of patients with COVID‐19 requiring mechanical ventilation: A single‐center observational study in Japan 2023 Text txt rdacontent Computermedien c rdamedia Online-Ressource cr rdacarrier Abstract Aim Coronavirus disease (COVID‐19) spread worldwide, and was declared as a pandemic by the World Health Organization. Despite numerous studies in the last few years, the factors associated with the outcomes of patients with COVID‐19 requiring mechanical ventilation remain unclear. The prediction of ventilator weaning and mortality using the data obtained at the time of intubation could be beneficial for establishing appropriate treatment strategies and obtaining informed consent. In this study, we aimed to clarify the association between patient information at the time of intubation and the outcomes of intubated COVID‐19 patients. Methods This retrospective observational study used single‐center data from patients with COVID‐19. Patients with COVID‐19 who were admitted to Osaka Metropolitan University Hospital from April 1, 2020, to March 31, 2022, and under mechanical ventilation were included. The main outcome was defined as the factors related to ventilator weaning; a multivariate analysis was carried out to evaluate the association between patient information at the time of intubation and the outcome. Results In total, 146 patients were included in this study. The factors significantly associated with ventilator weaning were age (65–74 years old, adjusted odds ratio [OR], 0.168; 75 years and older, adjusted OR, 0.121), vaccination history (adjusted OR, 5.655), and Sequential Organ Failure Assessment (SOFA) respiration score (adjusted OR, 0.007) at the time of intubation. Conclusion Age, SOFA respiration score, and COVID‐19 vaccination history at the time of intubation could be associated with outcomes in patients with COVID‐19 requiring mechanical ventilation. COVID‐19 mechanical ventilation prognostic factor ventilator weaning Medical emergencies. Critical care. Intensive care. First aid Tetsuro Nishimura verfasserin aut Kenji Matsuo verfasserin aut Fumiaki Wakita verfasserin aut Akihiro Kawamoto verfasserin aut Kenichiro Uchida verfasserin aut Hiromasa Yamamoto verfasserin aut Koichi Yamada verfasserin aut Hiroshi Kakeya verfasserin aut Hiromichi Fujii verfasserin aut Toshihiko Shibata verfasserin aut Yasumitsu Mizobata verfasserin aut In Acute Medicine & Surgery Wiley, 2018 10(2023), 1, Seite n/a-n/a (DE-627)776855808 (DE-600)2751184-4 20528817 nnns volume:10 year:2023 number:1 pages:n/a-n/a https://doi.org/10.1002/ams2.868 kostenfrei https://doaj.org/article/7b8eb458017f44858ddfc7d7c03b2c8f kostenfrei https://doi.org/10.1002/ams2.868 kostenfrei https://doaj.org/toc/2052-8817 Journal toc kostenfrei GBV_USEFLAG_A SYSFLAG_A GBV_DOAJ GBV_ILN_20 GBV_ILN_22 GBV_ILN_23 GBV_ILN_24 GBV_ILN_31 GBV_ILN_39 GBV_ILN_40 GBV_ILN_60 GBV_ILN_62 GBV_ILN_63 GBV_ILN_65 GBV_ILN_69 GBV_ILN_73 GBV_ILN_74 GBV_ILN_95 GBV_ILN_105 GBV_ILN_110 GBV_ILN_151 GBV_ILN_161 GBV_ILN_170 GBV_ILN_171 GBV_ILN_206 GBV_ILN_213 GBV_ILN_224 GBV_ILN_230 GBV_ILN_285 GBV_ILN_293 GBV_ILN_602 GBV_ILN_636 GBV_ILN_2004 GBV_ILN_2005 GBV_ILN_2006 GBV_ILN_2007 GBV_ILN_2010 GBV_ILN_2011 GBV_ILN_2014 GBV_ILN_2026 GBV_ILN_2027 GBV_ILN_2034 GBV_ILN_2037 GBV_ILN_2038 GBV_ILN_2044 GBV_ILN_2048 GBV_ILN_2049 GBV_ILN_2050 GBV_ILN_2055 GBV_ILN_2056 GBV_ILN_2057 GBV_ILN_2059 GBV_ILN_2061 GBV_ILN_2064 GBV_ILN_2068 GBV_ILN_2088 GBV_ILN_2106 GBV_ILN_2108 GBV_ILN_2110 GBV_ILN_2111 GBV_ILN_2118 GBV_ILN_2122 GBV_ILN_2143 GBV_ILN_2144 GBV_ILN_2147 GBV_ILN_2148 GBV_ILN_2152 GBV_ILN_2153 GBV_ILN_2232 GBV_ILN_2336 GBV_ILN_2470 GBV_ILN_2507 GBV_ILN_2522 GBV_ILN_4012 GBV_ILN_4035 GBV_ILN_4037 GBV_ILN_4046 GBV_ILN_4112 GBV_ILN_4125 GBV_ILN_4126 GBV_ILN_4242 GBV_ILN_4249 GBV_ILN_4251 GBV_ILN_4305 GBV_ILN_4306 GBV_ILN_4307 GBV_ILN_4313 GBV_ILN_4322 GBV_ILN_4323 GBV_ILN_4324 GBV_ILN_4325 GBV_ILN_4326 GBV_ILN_4333 GBV_ILN_4334 GBV_ILN_4335 GBV_ILN_4336 GBV_ILN_4338 GBV_ILN_4367 GBV_ILN_4700 AR 10 2023 1 n/a-n/a |
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10.1002/ams2.868 doi (DE-627)DOAJ098063073 (DE-599)DOAJ7b8eb458017f44858ddfc7d7c03b2c8f DE-627 ger DE-627 rakwb eng RC86-88.9 Ryo Deguchi verfasserin aut Factors associated with the outcome of patients with COVID‐19 requiring mechanical ventilation: A single‐center observational study in Japan 2023 Text txt rdacontent Computermedien c rdamedia Online-Ressource cr rdacarrier Abstract Aim Coronavirus disease (COVID‐19) spread worldwide, and was declared as a pandemic by the World Health Organization. Despite numerous studies in the last few years, the factors associated with the outcomes of patients with COVID‐19 requiring mechanical ventilation remain unclear. The prediction of ventilator weaning and mortality using the data obtained at the time of intubation could be beneficial for establishing appropriate treatment strategies and obtaining informed consent. In this study, we aimed to clarify the association between patient information at the time of intubation and the outcomes of intubated COVID‐19 patients. Methods This retrospective observational study used single‐center data from patients with COVID‐19. Patients with COVID‐19 who were admitted to Osaka Metropolitan University Hospital from April 1, 2020, to March 31, 2022, and under mechanical ventilation were included. The main outcome was defined as the factors related to ventilator weaning; a multivariate analysis was carried out to evaluate the association between patient information at the time of intubation and the outcome. Results In total, 146 patients were included in this study. The factors significantly associated with ventilator weaning were age (65–74 years old, adjusted odds ratio [OR], 0.168; 75 years and older, adjusted OR, 0.121), vaccination history (adjusted OR, 5.655), and Sequential Organ Failure Assessment (SOFA) respiration score (adjusted OR, 0.007) at the time of intubation. Conclusion Age, SOFA respiration score, and COVID‐19 vaccination history at the time of intubation could be associated with outcomes in patients with COVID‐19 requiring mechanical ventilation. COVID‐19 mechanical ventilation prognostic factor ventilator weaning Medical emergencies. Critical care. Intensive care. First aid Tetsuro Nishimura verfasserin aut Kenji Matsuo verfasserin aut Fumiaki Wakita verfasserin aut Akihiro Kawamoto verfasserin aut Kenichiro Uchida verfasserin aut Hiromasa Yamamoto verfasserin aut Koichi Yamada verfasserin aut Hiroshi Kakeya verfasserin aut Hiromichi Fujii verfasserin aut Toshihiko Shibata verfasserin aut Yasumitsu Mizobata verfasserin aut In Acute Medicine & Surgery Wiley, 2018 10(2023), 1, Seite n/a-n/a (DE-627)776855808 (DE-600)2751184-4 20528817 nnns volume:10 year:2023 number:1 pages:n/a-n/a https://doi.org/10.1002/ams2.868 kostenfrei https://doaj.org/article/7b8eb458017f44858ddfc7d7c03b2c8f kostenfrei https://doi.org/10.1002/ams2.868 kostenfrei https://doaj.org/toc/2052-8817 Journal toc kostenfrei GBV_USEFLAG_A SYSFLAG_A GBV_DOAJ GBV_ILN_20 GBV_ILN_22 GBV_ILN_23 GBV_ILN_24 GBV_ILN_31 GBV_ILN_39 GBV_ILN_40 GBV_ILN_60 GBV_ILN_62 GBV_ILN_63 GBV_ILN_65 GBV_ILN_69 GBV_ILN_73 GBV_ILN_74 GBV_ILN_95 GBV_ILN_105 GBV_ILN_110 GBV_ILN_151 GBV_ILN_161 GBV_ILN_170 GBV_ILN_171 GBV_ILN_206 GBV_ILN_213 GBV_ILN_224 GBV_ILN_230 GBV_ILN_285 GBV_ILN_293 GBV_ILN_602 GBV_ILN_636 GBV_ILN_2004 GBV_ILN_2005 GBV_ILN_2006 GBV_ILN_2007 GBV_ILN_2010 GBV_ILN_2011 GBV_ILN_2014 GBV_ILN_2026 GBV_ILN_2027 GBV_ILN_2034 GBV_ILN_2037 GBV_ILN_2038 GBV_ILN_2044 GBV_ILN_2048 GBV_ILN_2049 GBV_ILN_2050 GBV_ILN_2055 GBV_ILN_2056 GBV_ILN_2057 GBV_ILN_2059 GBV_ILN_2061 GBV_ILN_2064 GBV_ILN_2068 GBV_ILN_2088 GBV_ILN_2106 GBV_ILN_2108 GBV_ILN_2110 GBV_ILN_2111 GBV_ILN_2118 GBV_ILN_2122 GBV_ILN_2143 GBV_ILN_2144 GBV_ILN_2147 GBV_ILN_2148 GBV_ILN_2152 GBV_ILN_2153 GBV_ILN_2232 GBV_ILN_2336 GBV_ILN_2470 GBV_ILN_2507 GBV_ILN_2522 GBV_ILN_4012 GBV_ILN_4035 GBV_ILN_4037 GBV_ILN_4046 GBV_ILN_4112 GBV_ILN_4125 GBV_ILN_4126 GBV_ILN_4242 GBV_ILN_4249 GBV_ILN_4251 GBV_ILN_4305 GBV_ILN_4306 GBV_ILN_4307 GBV_ILN_4313 GBV_ILN_4322 GBV_ILN_4323 GBV_ILN_4324 GBV_ILN_4325 GBV_ILN_4326 GBV_ILN_4333 GBV_ILN_4334 GBV_ILN_4335 GBV_ILN_4336 GBV_ILN_4338 GBV_ILN_4367 GBV_ILN_4700 AR 10 2023 1 n/a-n/a |
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10.1002/ams2.868 doi (DE-627)DOAJ098063073 (DE-599)DOAJ7b8eb458017f44858ddfc7d7c03b2c8f DE-627 ger DE-627 rakwb eng RC86-88.9 Ryo Deguchi verfasserin aut Factors associated with the outcome of patients with COVID‐19 requiring mechanical ventilation: A single‐center observational study in Japan 2023 Text txt rdacontent Computermedien c rdamedia Online-Ressource cr rdacarrier Abstract Aim Coronavirus disease (COVID‐19) spread worldwide, and was declared as a pandemic by the World Health Organization. Despite numerous studies in the last few years, the factors associated with the outcomes of patients with COVID‐19 requiring mechanical ventilation remain unclear. The prediction of ventilator weaning and mortality using the data obtained at the time of intubation could be beneficial for establishing appropriate treatment strategies and obtaining informed consent. In this study, we aimed to clarify the association between patient information at the time of intubation and the outcomes of intubated COVID‐19 patients. Methods This retrospective observational study used single‐center data from patients with COVID‐19. Patients with COVID‐19 who were admitted to Osaka Metropolitan University Hospital from April 1, 2020, to March 31, 2022, and under mechanical ventilation were included. The main outcome was defined as the factors related to ventilator weaning; a multivariate analysis was carried out to evaluate the association between patient information at the time of intubation and the outcome. Results In total, 146 patients were included in this study. The factors significantly associated with ventilator weaning were age (65–74 years old, adjusted odds ratio [OR], 0.168; 75 years and older, adjusted OR, 0.121), vaccination history (adjusted OR, 5.655), and Sequential Organ Failure Assessment (SOFA) respiration score (adjusted OR, 0.007) at the time of intubation. Conclusion Age, SOFA respiration score, and COVID‐19 vaccination history at the time of intubation could be associated with outcomes in patients with COVID‐19 requiring mechanical ventilation. COVID‐19 mechanical ventilation prognostic factor ventilator weaning Medical emergencies. Critical care. Intensive care. First aid Tetsuro Nishimura verfasserin aut Kenji Matsuo verfasserin aut Fumiaki Wakita verfasserin aut Akihiro Kawamoto verfasserin aut Kenichiro Uchida verfasserin aut Hiromasa Yamamoto verfasserin aut Koichi Yamada verfasserin aut Hiroshi Kakeya verfasserin aut Hiromichi Fujii verfasserin aut Toshihiko Shibata verfasserin aut Yasumitsu Mizobata verfasserin aut In Acute Medicine & Surgery Wiley, 2018 10(2023), 1, Seite n/a-n/a (DE-627)776855808 (DE-600)2751184-4 20528817 nnns volume:10 year:2023 number:1 pages:n/a-n/a https://doi.org/10.1002/ams2.868 kostenfrei https://doaj.org/article/7b8eb458017f44858ddfc7d7c03b2c8f kostenfrei https://doi.org/10.1002/ams2.868 kostenfrei https://doaj.org/toc/2052-8817 Journal toc kostenfrei GBV_USEFLAG_A SYSFLAG_A GBV_DOAJ GBV_ILN_20 GBV_ILN_22 GBV_ILN_23 GBV_ILN_24 GBV_ILN_31 GBV_ILN_39 GBV_ILN_40 GBV_ILN_60 GBV_ILN_62 GBV_ILN_63 GBV_ILN_65 GBV_ILN_69 GBV_ILN_73 GBV_ILN_74 GBV_ILN_95 GBV_ILN_105 GBV_ILN_110 GBV_ILN_151 GBV_ILN_161 GBV_ILN_170 GBV_ILN_171 GBV_ILN_206 GBV_ILN_213 GBV_ILN_224 GBV_ILN_230 GBV_ILN_285 GBV_ILN_293 GBV_ILN_602 GBV_ILN_636 GBV_ILN_2004 GBV_ILN_2005 GBV_ILN_2006 GBV_ILN_2007 GBV_ILN_2010 GBV_ILN_2011 GBV_ILN_2014 GBV_ILN_2026 GBV_ILN_2027 GBV_ILN_2034 GBV_ILN_2037 GBV_ILN_2038 GBV_ILN_2044 GBV_ILN_2048 GBV_ILN_2049 GBV_ILN_2050 GBV_ILN_2055 GBV_ILN_2056 GBV_ILN_2057 GBV_ILN_2059 GBV_ILN_2061 GBV_ILN_2064 GBV_ILN_2068 GBV_ILN_2088 GBV_ILN_2106 GBV_ILN_2108 GBV_ILN_2110 GBV_ILN_2111 GBV_ILN_2118 GBV_ILN_2122 GBV_ILN_2143 GBV_ILN_2144 GBV_ILN_2147 GBV_ILN_2148 GBV_ILN_2152 GBV_ILN_2153 GBV_ILN_2232 GBV_ILN_2336 GBV_ILN_2470 GBV_ILN_2507 GBV_ILN_2522 GBV_ILN_4012 GBV_ILN_4035 GBV_ILN_4037 GBV_ILN_4046 GBV_ILN_4112 GBV_ILN_4125 GBV_ILN_4126 GBV_ILN_4242 GBV_ILN_4249 GBV_ILN_4251 GBV_ILN_4305 GBV_ILN_4306 GBV_ILN_4307 GBV_ILN_4313 GBV_ILN_4322 GBV_ILN_4323 GBV_ILN_4324 GBV_ILN_4325 GBV_ILN_4326 GBV_ILN_4333 GBV_ILN_4334 GBV_ILN_4335 GBV_ILN_4336 GBV_ILN_4338 GBV_ILN_4367 GBV_ILN_4700 AR 10 2023 1 n/a-n/a |
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Ryo Deguchi @@aut@@ Tetsuro Nishimura @@aut@@ Kenji Matsuo @@aut@@ Fumiaki Wakita @@aut@@ Akihiro Kawamoto @@aut@@ Kenichiro Uchida @@aut@@ Hiromasa Yamamoto @@aut@@ Koichi Yamada @@aut@@ Hiroshi Kakeya @@aut@@ Hiromichi Fujii @@aut@@ Toshihiko Shibata @@aut@@ Yasumitsu Mizobata @@aut@@ |
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Despite numerous studies in the last few years, the factors associated with the outcomes of patients with COVID‐19 requiring mechanical ventilation remain unclear. The prediction of ventilator weaning and mortality using the data obtained at the time of intubation could be beneficial for establishing appropriate treatment strategies and obtaining informed consent. In this study, we aimed to clarify the association between patient information at the time of intubation and the outcomes of intubated COVID‐19 patients. Methods This retrospective observational study used single‐center data from patients with COVID‐19. Patients with COVID‐19 who were admitted to Osaka Metropolitan University Hospital from April 1, 2020, to March 31, 2022, and under mechanical ventilation were included. The main outcome was defined as the factors related to ventilator weaning; a multivariate analysis was carried out to evaluate the association between patient information at the time of intubation and the outcome. Results In total, 146 patients were included in this study. The factors significantly associated with ventilator weaning were age (65–74 years old, adjusted odds ratio [OR], 0.168; 75 years and older, adjusted OR, 0.121), vaccination history (adjusted OR, 5.655), and Sequential Organ Failure Assessment (SOFA) respiration score (adjusted OR, 0.007) at the time of intubation. 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Ryo Deguchi |
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Ryo Deguchi misc RC86-88.9 misc COVID‐19 misc mechanical ventilation misc prognostic factor misc ventilator weaning misc Medical emergencies. Critical care. Intensive care. First aid Factors associated with the outcome of patients with COVID‐19 requiring mechanical ventilation: A single‐center observational study in Japan |
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RC86-88.9 Factors associated with the outcome of patients with COVID‐19 requiring mechanical ventilation: A single‐center observational study in Japan COVID‐19 mechanical ventilation prognostic factor ventilator weaning |
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misc RC86-88.9 misc COVID‐19 misc mechanical ventilation misc prognostic factor misc ventilator weaning misc Medical emergencies. Critical care. Intensive care. First aid |
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misc RC86-88.9 misc COVID‐19 misc mechanical ventilation misc prognostic factor misc ventilator weaning misc Medical emergencies. Critical care. Intensive care. First aid |
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Factors associated with the outcome of patients with COVID‐19 requiring mechanical ventilation: A single‐center observational study in Japan |
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factors associated with the outcome of patients with covid‐19 requiring mechanical ventilation: a single‐center observational study in japan |
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Factors associated with the outcome of patients with COVID‐19 requiring mechanical ventilation: A single‐center observational study in Japan |
| abstract |
Abstract Aim Coronavirus disease (COVID‐19) spread worldwide, and was declared as a pandemic by the World Health Organization. Despite numerous studies in the last few years, the factors associated with the outcomes of patients with COVID‐19 requiring mechanical ventilation remain unclear. The prediction of ventilator weaning and mortality using the data obtained at the time of intubation could be beneficial for establishing appropriate treatment strategies and obtaining informed consent. In this study, we aimed to clarify the association between patient information at the time of intubation and the outcomes of intubated COVID‐19 patients. Methods This retrospective observational study used single‐center data from patients with COVID‐19. Patients with COVID‐19 who were admitted to Osaka Metropolitan University Hospital from April 1, 2020, to March 31, 2022, and under mechanical ventilation were included. The main outcome was defined as the factors related to ventilator weaning; a multivariate analysis was carried out to evaluate the association between patient information at the time of intubation and the outcome. Results In total, 146 patients were included in this study. The factors significantly associated with ventilator weaning were age (65–74 years old, adjusted odds ratio [OR], 0.168; 75 years and older, adjusted OR, 0.121), vaccination history (adjusted OR, 5.655), and Sequential Organ Failure Assessment (SOFA) respiration score (adjusted OR, 0.007) at the time of intubation. Conclusion Age, SOFA respiration score, and COVID‐19 vaccination history at the time of intubation could be associated with outcomes in patients with COVID‐19 requiring mechanical ventilation. |
| abstractGer |
Abstract Aim Coronavirus disease (COVID‐19) spread worldwide, and was declared as a pandemic by the World Health Organization. Despite numerous studies in the last few years, the factors associated with the outcomes of patients with COVID‐19 requiring mechanical ventilation remain unclear. The prediction of ventilator weaning and mortality using the data obtained at the time of intubation could be beneficial for establishing appropriate treatment strategies and obtaining informed consent. In this study, we aimed to clarify the association between patient information at the time of intubation and the outcomes of intubated COVID‐19 patients. Methods This retrospective observational study used single‐center data from patients with COVID‐19. Patients with COVID‐19 who were admitted to Osaka Metropolitan University Hospital from April 1, 2020, to March 31, 2022, and under mechanical ventilation were included. The main outcome was defined as the factors related to ventilator weaning; a multivariate analysis was carried out to evaluate the association between patient information at the time of intubation and the outcome. Results In total, 146 patients were included in this study. The factors significantly associated with ventilator weaning were age (65–74 years old, adjusted odds ratio [OR], 0.168; 75 years and older, adjusted OR, 0.121), vaccination history (adjusted OR, 5.655), and Sequential Organ Failure Assessment (SOFA) respiration score (adjusted OR, 0.007) at the time of intubation. Conclusion Age, SOFA respiration score, and COVID‐19 vaccination history at the time of intubation could be associated with outcomes in patients with COVID‐19 requiring mechanical ventilation. |
| abstract_unstemmed |
Abstract Aim Coronavirus disease (COVID‐19) spread worldwide, and was declared as a pandemic by the World Health Organization. Despite numerous studies in the last few years, the factors associated with the outcomes of patients with COVID‐19 requiring mechanical ventilation remain unclear. The prediction of ventilator weaning and mortality using the data obtained at the time of intubation could be beneficial for establishing appropriate treatment strategies and obtaining informed consent. In this study, we aimed to clarify the association between patient information at the time of intubation and the outcomes of intubated COVID‐19 patients. Methods This retrospective observational study used single‐center data from patients with COVID‐19. Patients with COVID‐19 who were admitted to Osaka Metropolitan University Hospital from April 1, 2020, to March 31, 2022, and under mechanical ventilation were included. The main outcome was defined as the factors related to ventilator weaning; a multivariate analysis was carried out to evaluate the association between patient information at the time of intubation and the outcome. Results In total, 146 patients were included in this study. The factors significantly associated with ventilator weaning were age (65–74 years old, adjusted odds ratio [OR], 0.168; 75 years and older, adjusted OR, 0.121), vaccination history (adjusted OR, 5.655), and Sequential Organ Failure Assessment (SOFA) respiration score (adjusted OR, 0.007) at the time of intubation. Conclusion Age, SOFA respiration score, and COVID‐19 vaccination history at the time of intubation could be associated with outcomes in patients with COVID‐19 requiring mechanical ventilation. |
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<?xml version="1.0" encoding="UTF-8"?><collection xmlns="http://www.loc.gov/MARC21/slim"><record><leader>01000naa a22002652 4500</leader><controlfield tag="001">DOAJ098063073</controlfield><controlfield tag="003">DE-627</controlfield><controlfield tag="005">20240413203330.0</controlfield><controlfield tag="007">cr uuu---uuuuu</controlfield><controlfield tag="008">240413s2023 xx |||||o 00| ||eng c</controlfield><datafield tag="024" ind1="7" ind2=" "><subfield code="a">10.1002/ams2.868</subfield><subfield code="2">doi</subfield></datafield><datafield tag="035" ind1=" " ind2=" "><subfield code="a">(DE-627)DOAJ098063073</subfield></datafield><datafield tag="035" ind1=" " ind2=" "><subfield code="a">(DE-599)DOAJ7b8eb458017f44858ddfc7d7c03b2c8f</subfield></datafield><datafield tag="040" ind1=" " ind2=" "><subfield code="a">DE-627</subfield><subfield code="b">ger</subfield><subfield code="c">DE-627</subfield><subfield code="e">rakwb</subfield></datafield><datafield tag="041" ind1=" " ind2=" "><subfield code="a">eng</subfield></datafield><datafield tag="050" ind1=" " ind2="0"><subfield code="a">RC86-88.9</subfield></datafield><datafield tag="100" ind1="0" ind2=" "><subfield code="a">Ryo Deguchi</subfield><subfield code="e">verfasserin</subfield><subfield code="4">aut</subfield></datafield><datafield tag="245" ind1="1" ind2="0"><subfield code="a">Factors associated with the outcome of patients with COVID‐19 requiring mechanical ventilation: A single‐center observational study in Japan</subfield></datafield><datafield tag="264" ind1=" " ind2="1"><subfield code="c">2023</subfield></datafield><datafield tag="336" ind1=" " ind2=" "><subfield code="a">Text</subfield><subfield code="b">txt</subfield><subfield code="2">rdacontent</subfield></datafield><datafield tag="337" ind1=" " ind2=" "><subfield code="a">Computermedien</subfield><subfield code="b">c</subfield><subfield code="2">rdamedia</subfield></datafield><datafield tag="338" ind1=" " ind2=" "><subfield code="a">Online-Ressource</subfield><subfield code="b">cr</subfield><subfield code="2">rdacarrier</subfield></datafield><datafield tag="520" ind1=" " ind2=" "><subfield code="a">Abstract Aim Coronavirus disease (COVID‐19) spread worldwide, and was declared as a pandemic by the World Health Organization. Despite numerous studies in the last few years, the factors associated with the outcomes of patients with COVID‐19 requiring mechanical ventilation remain unclear. The prediction of ventilator weaning and mortality using the data obtained at the time of intubation could be beneficial for establishing appropriate treatment strategies and obtaining informed consent. In this study, we aimed to clarify the association between patient information at the time of intubation and the outcomes of intubated COVID‐19 patients. Methods This retrospective observational study used single‐center data from patients with COVID‐19. Patients with COVID‐19 who were admitted to Osaka Metropolitan University Hospital from April 1, 2020, to March 31, 2022, and under mechanical ventilation were included. The main outcome was defined as the factors related to ventilator weaning; a multivariate analysis was carried out to evaluate the association between patient information at the time of intubation and the outcome. Results In total, 146 patients were included in this study. The factors significantly associated with ventilator weaning were age (65–74 years old, adjusted odds ratio [OR], 0.168; 75 years and older, adjusted OR, 0.121), vaccination history (adjusted OR, 5.655), and Sequential Organ Failure Assessment (SOFA) respiration score (adjusted OR, 0.007) at the time of intubation. 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