Fusion Biopsy, not Cognitive, Is the New Gold Standard

To date, although some benefits resulting from a software-guided technique are undeniable, no clear superiority of fusion over cognitive targeted biopsy (COG-TB) has been supported by strong evidence. We discuss potential causes of trials failing to show the superiority of fusion TB (FUS-TB) and hig...
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Autor*in:	Alessandro Marquis [verfasserIn] Giancarlo Marra [verfasserIn] Paolo Gontero [verfasserIn]

Format:	E-Artikel
Sprache:	Englisch

Erschienen:	2023

Schlagwörter:	prostate biopsy targeted prostate biopsy fusion prostate biopsy cognitive prostate biopsy prostate cancer

Übergeordnetes Werk:	In: Société Internationale d’Urologie Journal - MDPI AG, 2021, 4(2023), 2, Seite 142-144
Übergeordnetes Werk:	volume:4 ; year:2023 ; number:2 ; pages:142-144

Links:	Link aufrufen Link aufrufen Link aufrufen Journal toc

DOI / URN:	10.48083//RYRF4858

Katalog-ID:	DOAJ098298011

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source	In Société Internationale d’Urologie Journal 4(2023), 2, Seite 142-144 volume:4 year:2023 number:2 pages:142-144
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topic_facet	prostate biopsy targeted prostate biopsy fusion prostate biopsy cognitive prostate biopsy prostate cancer Diseases of the genitourinary system. Urology
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callnumber-first	R - Medicine
author	Alessandro Marquis
spellingShingle	Alessandro Marquis misc RC870-923 misc prostate biopsy misc targeted prostate biopsy misc fusion prostate biopsy misc cognitive prostate biopsy misc prostate cancer misc Diseases of the genitourinary system. Urology Fusion Biopsy, not Cognitive, Is the New Gold Standard
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topic_title	RC870-923 Fusion Biopsy, not Cognitive, Is the New Gold Standard prostate biopsy targeted prostate biopsy fusion prostate biopsy cognitive prostate biopsy prostate cancer
topic	misc RC870-923 misc prostate biopsy misc targeted prostate biopsy misc fusion prostate biopsy misc cognitive prostate biopsy misc prostate cancer misc Diseases of the genitourinary system. Urology
topic_unstemmed	misc RC870-923 misc prostate biopsy misc targeted prostate biopsy misc fusion prostate biopsy misc cognitive prostate biopsy misc prostate cancer misc Diseases of the genitourinary system. Urology
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title	Fusion Biopsy, not Cognitive, Is the New Gold Standard
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title_full	Fusion Biopsy, not Cognitive, Is the New Gold Standard
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title_sort	fusion biopsy, not cognitive, is the new gold standard
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title_auth	Fusion Biopsy, not Cognitive, Is the New Gold Standard
abstract	To date, although some benefits resulting from a software-guided technique are undeniable, no clear superiority of fusion over cognitive targeted biopsy (COG-TB) has been supported by strong evidence. We discuss potential causes of trials failing to show the superiority of fusion TB (FUS-TB) and highlight its advantages over the cognitive approach.One possible reason why current literature showed contradictory evidence in supporting FUS-TB may be the lack of high-quality well-designed trials. Indeed, most of the studies addressing this issue have considerable limitations, such as underpowering, small sample size, lack of randomization, and poor generalizability. A second reason may be the inclusion in the majority of trials of a wide spectrum of MRI-lesions, a scenario in which the benefits of FUS-TB may be less evident. In fact, some of the few studies considering smaller targets demonstrated higher accuracy for the FUS technique. As concerns the advantages of FUS-TB, the opportunity offered by some fusion systems of storing information useful for planning and/or follow-up active surveillance, focal therapy, and radical prostatectomy, as well as a reported faster learning curve, are strong points supporting the fusion approach.In conclusion, the potential advantages when targeting smaller lesions together with the storage capability to guide patient management after the biopsy and an easier learning curve may make the FUS approach the more appropriate technique for performing TB.
abstractGer	To date, although some benefits resulting from a software-guided technique are undeniable, no clear superiority of fusion over cognitive targeted biopsy (COG-TB) has been supported by strong evidence. We discuss potential causes of trials failing to show the superiority of fusion TB (FUS-TB) and highlight its advantages over the cognitive approach.One possible reason why current literature showed contradictory evidence in supporting FUS-TB may be the lack of high-quality well-designed trials. Indeed, most of the studies addressing this issue have considerable limitations, such as underpowering, small sample size, lack of randomization, and poor generalizability. A second reason may be the inclusion in the majority of trials of a wide spectrum of MRI-lesions, a scenario in which the benefits of FUS-TB may be less evident. In fact, some of the few studies considering smaller targets demonstrated higher accuracy for the FUS technique. As concerns the advantages of FUS-TB, the opportunity offered by some fusion systems of storing information useful for planning and/or follow-up active surveillance, focal therapy, and radical prostatectomy, as well as a reported faster learning curve, are strong points supporting the fusion approach.In conclusion, the potential advantages when targeting smaller lesions together with the storage capability to guide patient management after the biopsy and an easier learning curve may make the FUS approach the more appropriate technique for performing TB.
abstract_unstemmed	To date, although some benefits resulting from a software-guided technique are undeniable, no clear superiority of fusion over cognitive targeted biopsy (COG-TB) has been supported by strong evidence. We discuss potential causes of trials failing to show the superiority of fusion TB (FUS-TB) and highlight its advantages over the cognitive approach.One possible reason why current literature showed contradictory evidence in supporting FUS-TB may be the lack of high-quality well-designed trials. Indeed, most of the studies addressing this issue have considerable limitations, such as underpowering, small sample size, lack of randomization, and poor generalizability. A second reason may be the inclusion in the majority of trials of a wide spectrum of MRI-lesions, a scenario in which the benefits of FUS-TB may be less evident. In fact, some of the few studies considering smaller targets demonstrated higher accuracy for the FUS technique. As concerns the advantages of FUS-TB, the opportunity offered by some fusion systems of storing information useful for planning and/or follow-up active surveillance, focal therapy, and radical prostatectomy, as well as a reported faster learning curve, are strong points supporting the fusion approach.In conclusion, the potential advantages when targeting smaller lesions together with the storage capability to guide patient management after the biopsy and an easier learning curve may make the FUS approach the more appropriate technique for performing TB.
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title_short	Fusion Biopsy, not Cognitive, Is the New Gold Standard
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