Prevalence of MLSB Phenotypes of <i<Staphylococcus aureus</i< isolates in a tertiary care hospital of Delhi

Against the backdrop of the ever-changing Staphylococcal resistance pattern, clindamycin remains a viable therapeutic alternative Variation of Clindamycin drug resistance patterns with geographic area make inducible clindamycin resistance testing imperative for all staphylococcal isolates to avoid t...
Ausführliche Beschreibung

Gespeichert in:

Autor*in:	Malika Grover [verfasserIn] Nisha Goyal [verfasserIn] Seema Gangar [verfasserIn] Narendra Pal Singh [verfasserIn]

Format:	E-Artikel
Sprache:	Englisch

Erschienen:	2023

Schlagwörter:	Staphylococcus aureus inducible clindamycin resistance constitutive clindamycin resistance MSB phenotype

Übergeordnetes Werk:	In: Healthcare in Low-resource Settings - PAGEPress Publications, 2013, 11(2023), 1
Übergeordnetes Werk:	volume:11 ; year:2023 ; number:1

Links:	Link aufrufen Link aufrufen Link aufrufen Journal toc

DOI / URN:	10.4081/hls.2023.11229

Katalog-ID:	DOAJ09871130X

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author	Malika Grover
spellingShingle	Malika Grover misc RA1-1270 misc Staphylococcus aureus misc inducible clindamycin resistance misc constitutive clindamycin resistance misc MSB phenotype misc Public aspects of medicine Prevalence of MLSB Phenotypes of <i<Staphylococcus aureus</i< isolates in a tertiary care hospital of Delhi
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topic_title	RA1-1270 Prevalence of MLSB Phenotypes of <i<Staphylococcus aureus</i< isolates in a tertiary care hospital of Delhi Staphylococcus aureus inducible clindamycin resistance constitutive clindamycin resistance MSB phenotype
topic	misc RA1-1270 misc Staphylococcus aureus misc inducible clindamycin resistance misc constitutive clindamycin resistance misc MSB phenotype misc Public aspects of medicine
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title	Prevalence of MLSB Phenotypes of <i<Staphylococcus aureus</i< isolates in a tertiary care hospital of Delhi
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title_full	Prevalence of MLSB Phenotypes of <i<Staphylococcus aureus</i< isolates in a tertiary care hospital of Delhi
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title_sort	prevalence of mlsb phenotypes of <i<staphylococcus aureus</i< isolates in a tertiary care hospital of delhi
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title_auth	Prevalence of MLSB Phenotypes of <i<Staphylococcus aureus</i< isolates in a tertiary care hospital of Delhi
abstract	Against the backdrop of the ever-changing Staphylococcal resistance pattern, clindamycin remains a viable therapeutic alternative Variation of Clindamycin drug resistance patterns with geographic area make inducible clindamycin resistance testing imperative for all staphylococcal isolates to avoid therapeutic failure. This was a prospective study conducted over a period of 1.5 years from January 2021 until June 2022. Prevalence of different MLSB Phenotypes of Staphylococcus aureus isolates was determined by standard disc diffusion method as per CLSI guidelines. Pyogenic samples received in the Microbiology lab that yielded Staphylococcus aureus were further tested for the presence of clindamycin resistance by disc diffusion method. Out of 6586 total pyogenic and respiratory specimens received in the lab, Staphylococcus aureus was yielded in 752 samples. On further testing for the MLSB phenotypes, 16.3% isolates were found to be iMLSB, 19.28% were cMLSB, 43.1% were of MSB type. ICR screening will reduce the unessential subjection of the patient to the antibiotic, and would prevent unnecessary adverse effects in the patients.
abstractGer	Against the backdrop of the ever-changing Staphylococcal resistance pattern, clindamycin remains a viable therapeutic alternative Variation of Clindamycin drug resistance patterns with geographic area make inducible clindamycin resistance testing imperative for all staphylococcal isolates to avoid therapeutic failure. This was a prospective study conducted over a period of 1.5 years from January 2021 until June 2022. Prevalence of different MLSB Phenotypes of Staphylococcus aureus isolates was determined by standard disc diffusion method as per CLSI guidelines. Pyogenic samples received in the Microbiology lab that yielded Staphylococcus aureus were further tested for the presence of clindamycin resistance by disc diffusion method. Out of 6586 total pyogenic and respiratory specimens received in the lab, Staphylococcus aureus was yielded in 752 samples. On further testing for the MLSB phenotypes, 16.3% isolates were found to be iMLSB, 19.28% were cMLSB, 43.1% were of MSB type. ICR screening will reduce the unessential subjection of the patient to the antibiotic, and would prevent unnecessary adverse effects in the patients.
abstract_unstemmed	Against the backdrop of the ever-changing Staphylococcal resistance pattern, clindamycin remains a viable therapeutic alternative Variation of Clindamycin drug resistance patterns with geographic area make inducible clindamycin resistance testing imperative for all staphylococcal isolates to avoid therapeutic failure. This was a prospective study conducted over a period of 1.5 years from January 2021 until June 2022. Prevalence of different MLSB Phenotypes of Staphylococcus aureus isolates was determined by standard disc diffusion method as per CLSI guidelines. Pyogenic samples received in the Microbiology lab that yielded Staphylococcus aureus were further tested for the presence of clindamycin resistance by disc diffusion method. Out of 6586 total pyogenic and respiratory specimens received in the lab, Staphylococcus aureus was yielded in 752 samples. On further testing for the MLSB phenotypes, 16.3% isolates were found to be iMLSB, 19.28% were cMLSB, 43.1% were of MSB type. ICR screening will reduce the unessential subjection of the patient to the antibiotic, and would prevent unnecessary adverse effects in the patients.
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title_short	Prevalence of MLSB Phenotypes of <i<Staphylococcus aureus</i< isolates in a tertiary care hospital of Delhi
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Prevalence of MLSB Phenotypes of <i<Staphylococcus aureus</i< isolates in a tertiary care hospital of Delhi

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