Mechanisms of action by sulphur compounds in Allium sativum. A review
Background: Allium sativum, the bulbous perennial plant of the Alliaceae family has been utilized as a very valuable remedy in the management of numerous diseases even from time immemorial. The plant exhibits antimicrobial activities over a wide range of microorganisms like parasites, fungi, virus a...
Ausführliche Beschreibung
Gespeichert in:
| Autor*in: |
Agatha Ngukuran Jikah [verfasserIn] Great Iruoghene Edo [verfasserIn] |
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| Format: |
E-Artikel |
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| Sprache: |
Englisch |
| Erschienen: |
2023 |
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| Schlagwörter: |
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| Übergeordnetes Werk: |
In: Pharmacological Research - Modern Chinese Medicine - Elsevier, 2021, 9(2023), Seite 100323- |
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| Übergeordnetes Werk: |
volume:9 ; year:2023 ; pages:100323- |
| Links: |
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| DOI / URN: |
10.1016/j.prmcm.2023.100323 |
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| Katalog-ID: |
DOAJ099159430 |
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| 520 | |a Background: Allium sativum, the bulbous perennial plant of the Alliaceae family has been utilized as a very valuable remedy in the management of numerous diseases even from time immemorial. The plant exhibits antimicrobial activities over a wide range of microorganisms like parasites, fungi, virus and other pathogens. This broad- spectrum of antimicrobial activity coupled with the low toxicity of Allium sativum are an attraction to scientists and thus it has been vastly employed as a therapeutic cure in contemporary society. The therapeutic properties of Allium sativum (antibacterial, antiviral, fungicidal, anti-cardiovascular disease, anticancer, antidiabetic, anti-blood pressure, antiatherosclerosis, antirheumatic, hyperlipidemia) are linked to the sulphur compounds it contains (diallyl disulfide, allicin, diallyl trisulfide, ajoene's, vinyl-dithiin, micronutrient selenium and S-allylcystein. Objectives: This review considers some sulphur compounds contained in Allium sativum and the mechanisms by which they elicit their biological actions. Method: The journals for this review paper were retrieved from prominent database sources like Academia.edu (https://www.academia.edu), PubMed (https://pubmed.ncbi.nlm.nih.gov/) and Web of science (https://access.clarivate.com). Both medical headings and free text keywords were employed in the search “biological activities of allicin”, “biosynthesis of sulphur compounds in garlic”, “sulphur compounds in garlic”, “mechanism of action of antibacterial action of ajoene”, “S-allylcystein in garlic”, “mechanism of neuroprotection by vinvyl-dithiin”, “anticancer actions of dially disulfide”, mechanism of anti-quorum sensing actions of ajoene, antihyperlipidemic activity of allicin, mechanism of anti-platelet actions of ajoene and other related information from related journals. Results: Allium sativum has many therapeutic properties; antibacterial, neuroprotection, antiviral, fungicidal, lipid metabolism, anti-cardiovascular disease, glucose metabolism, anticancer, antidiabetic, anti-blood pressure, antiatherosclerosis, antirheumatic, hyperlipidemia), these properties result from some sulphur compounds (diallyl disulfide, allicin, diallyl trisulfide, ajoene's, vinyl-dithiin, micronutrient selenium and S-allylcystein) which the plant contains. Conclusion: Within this paper, some sulphur containing phytonutrients in Allium sativum namely; allicin, ajoene, S-allylcystein, vinvyl-dithiin, dially disulfide, dially trisulfide and the mechanisms by which they carry out these actions are considered. The pharmaceutical and food industries have harnessed these phytochemicals in manufacturing both wellness and therapeutic products. Should more research be carried out on Allium sativum, safe and effective doses can be authenticated so that it can be safely included in the management of pathologies. | ||
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10.1016/j.prmcm.2023.100323 doi (DE-627)DOAJ099159430 (DE-599)DOAJ75368af4b2104cc2bc4c6107cccbedb0 DE-627 ger DE-627 rakwb eng RZ201-999 RM1-950 Agatha Ngukuran Jikah verfasserin aut Mechanisms of action by sulphur compounds in Allium sativum. A review 2023 Text txt rdacontent Computermedien c rdamedia Online-Ressource cr rdacarrier Background: Allium sativum, the bulbous perennial plant of the Alliaceae family has been utilized as a very valuable remedy in the management of numerous diseases even from time immemorial. The plant exhibits antimicrobial activities over a wide range of microorganisms like parasites, fungi, virus and other pathogens. This broad- spectrum of antimicrobial activity coupled with the low toxicity of Allium sativum are an attraction to scientists and thus it has been vastly employed as a therapeutic cure in contemporary society. The therapeutic properties of Allium sativum (antibacterial, antiviral, fungicidal, anti-cardiovascular disease, anticancer, antidiabetic, anti-blood pressure, antiatherosclerosis, antirheumatic, hyperlipidemia) are linked to the sulphur compounds it contains (diallyl disulfide, allicin, diallyl trisulfide, ajoene's, vinyl-dithiin, micronutrient selenium and S-allylcystein. Objectives: This review considers some sulphur compounds contained in Allium sativum and the mechanisms by which they elicit their biological actions. Method: The journals for this review paper were retrieved from prominent database sources like Academia.edu (https://www.academia.edu), PubMed (https://pubmed.ncbi.nlm.nih.gov/) and Web of science (https://access.clarivate.com). Both medical headings and free text keywords were employed in the search “biological activities of allicin”, “biosynthesis of sulphur compounds in garlic”, “sulphur compounds in garlic”, “mechanism of action of antibacterial action of ajoene”, “S-allylcystein in garlic”, “mechanism of neuroprotection by vinvyl-dithiin”, “anticancer actions of dially disulfide”, mechanism of anti-quorum sensing actions of ajoene, antihyperlipidemic activity of allicin, mechanism of anti-platelet actions of ajoene and other related information from related journals. Results: Allium sativum has many therapeutic properties; antibacterial, neuroprotection, antiviral, fungicidal, lipid metabolism, anti-cardiovascular disease, glucose metabolism, anticancer, antidiabetic, anti-blood pressure, antiatherosclerosis, antirheumatic, hyperlipidemia), these properties result from some sulphur compounds (diallyl disulfide, allicin, diallyl trisulfide, ajoene's, vinyl-dithiin, micronutrient selenium and S-allylcystein) which the plant contains. Conclusion: Within this paper, some sulphur containing phytonutrients in Allium sativum namely; allicin, ajoene, S-allylcystein, vinvyl-dithiin, dially disulfide, dially trisulfide and the mechanisms by which they carry out these actions are considered. The pharmaceutical and food industries have harnessed these phytochemicals in manufacturing both wellness and therapeutic products. Should more research be carried out on Allium sativum, safe and effective doses can be authenticated so that it can be safely included in the management of pathologies. Allium sativum Ajoene Allicin Diallyl disulfide Other systems of medicine Therapeutics. Pharmacology Great Iruoghene Edo verfasserin aut In Pharmacological Research - Modern Chinese Medicine Elsevier, 2021 9(2023), Seite 100323- (DE-627)1785333399 26671425 nnns volume:9 year:2023 pages:100323- https://doi.org/10.1016/j.prmcm.2023.100323 kostenfrei https://doaj.org/article/75368af4b2104cc2bc4c6107cccbedb0 kostenfrei http://www.sciencedirect.com/science/article/pii/S2667142523001094 kostenfrei https://doaj.org/toc/2667-1425 Journal toc kostenfrei GBV_USEFLAG_A SYSFLAG_A GBV_DOAJ GBV_ILN_20 GBV_ILN_22 GBV_ILN_23 GBV_ILN_24 GBV_ILN_31 GBV_ILN_39 GBV_ILN_40 GBV_ILN_60 GBV_ILN_62 GBV_ILN_63 GBV_ILN_65 GBV_ILN_69 GBV_ILN_73 GBV_ILN_74 GBV_ILN_95 GBV_ILN_105 GBV_ILN_110 GBV_ILN_151 GBV_ILN_161 GBV_ILN_170 GBV_ILN_206 GBV_ILN_213 GBV_ILN_224 GBV_ILN_230 GBV_ILN_285 GBV_ILN_293 GBV_ILN_602 GBV_ILN_2001 GBV_ILN_2003 GBV_ILN_2005 GBV_ILN_2006 GBV_ILN_2007 GBV_ILN_2008 GBV_ILN_2009 GBV_ILN_2010 GBV_ILN_2011 GBV_ILN_2014 GBV_ILN_2015 GBV_ILN_2020 GBV_ILN_2021 GBV_ILN_2025 GBV_ILN_2026 GBV_ILN_2027 GBV_ILN_2034 GBV_ILN_2038 GBV_ILN_2044 GBV_ILN_2048 GBV_ILN_2049 GBV_ILN_2050 GBV_ILN_2055 GBV_ILN_2056 GBV_ILN_2059 GBV_ILN_2061 GBV_ILN_2064 GBV_ILN_2088 GBV_ILN_2106 GBV_ILN_2110 GBV_ILN_2112 GBV_ILN_2122 GBV_ILN_2129 GBV_ILN_2143 GBV_ILN_2152 GBV_ILN_2153 GBV_ILN_2190 GBV_ILN_2232 GBV_ILN_2336 GBV_ILN_2470 GBV_ILN_2507 GBV_ILN_4012 GBV_ILN_4035 GBV_ILN_4037 GBV_ILN_4112 GBV_ILN_4125 GBV_ILN_4126 GBV_ILN_4242 GBV_ILN_4249 GBV_ILN_4251 GBV_ILN_4305 GBV_ILN_4306 GBV_ILN_4307 GBV_ILN_4313 GBV_ILN_4322 GBV_ILN_4323 GBV_ILN_4324 GBV_ILN_4325 GBV_ILN_4326 GBV_ILN_4333 GBV_ILN_4334 GBV_ILN_4338 GBV_ILN_4367 GBV_ILN_4393 GBV_ILN_4700 AR 9 2023 100323- |
| spelling |
10.1016/j.prmcm.2023.100323 doi (DE-627)DOAJ099159430 (DE-599)DOAJ75368af4b2104cc2bc4c6107cccbedb0 DE-627 ger DE-627 rakwb eng RZ201-999 RM1-950 Agatha Ngukuran Jikah verfasserin aut Mechanisms of action by sulphur compounds in Allium sativum. A review 2023 Text txt rdacontent Computermedien c rdamedia Online-Ressource cr rdacarrier Background: Allium sativum, the bulbous perennial plant of the Alliaceae family has been utilized as a very valuable remedy in the management of numerous diseases even from time immemorial. The plant exhibits antimicrobial activities over a wide range of microorganisms like parasites, fungi, virus and other pathogens. This broad- spectrum of antimicrobial activity coupled with the low toxicity of Allium sativum are an attraction to scientists and thus it has been vastly employed as a therapeutic cure in contemporary society. The therapeutic properties of Allium sativum (antibacterial, antiviral, fungicidal, anti-cardiovascular disease, anticancer, antidiabetic, anti-blood pressure, antiatherosclerosis, antirheumatic, hyperlipidemia) are linked to the sulphur compounds it contains (diallyl disulfide, allicin, diallyl trisulfide, ajoene's, vinyl-dithiin, micronutrient selenium and S-allylcystein. Objectives: This review considers some sulphur compounds contained in Allium sativum and the mechanisms by which they elicit their biological actions. Method: The journals for this review paper were retrieved from prominent database sources like Academia.edu (https://www.academia.edu), PubMed (https://pubmed.ncbi.nlm.nih.gov/) and Web of science (https://access.clarivate.com). Both medical headings and free text keywords were employed in the search “biological activities of allicin”, “biosynthesis of sulphur compounds in garlic”, “sulphur compounds in garlic”, “mechanism of action of antibacterial action of ajoene”, “S-allylcystein in garlic”, “mechanism of neuroprotection by vinvyl-dithiin”, “anticancer actions of dially disulfide”, mechanism of anti-quorum sensing actions of ajoene, antihyperlipidemic activity of allicin, mechanism of anti-platelet actions of ajoene and other related information from related journals. Results: Allium sativum has many therapeutic properties; antibacterial, neuroprotection, antiviral, fungicidal, lipid metabolism, anti-cardiovascular disease, glucose metabolism, anticancer, antidiabetic, anti-blood pressure, antiatherosclerosis, antirheumatic, hyperlipidemia), these properties result from some sulphur compounds (diallyl disulfide, allicin, diallyl trisulfide, ajoene's, vinyl-dithiin, micronutrient selenium and S-allylcystein) which the plant contains. Conclusion: Within this paper, some sulphur containing phytonutrients in Allium sativum namely; allicin, ajoene, S-allylcystein, vinvyl-dithiin, dially disulfide, dially trisulfide and the mechanisms by which they carry out these actions are considered. The pharmaceutical and food industries have harnessed these phytochemicals in manufacturing both wellness and therapeutic products. Should more research be carried out on Allium sativum, safe and effective doses can be authenticated so that it can be safely included in the management of pathologies. Allium sativum Ajoene Allicin Diallyl disulfide Other systems of medicine Therapeutics. Pharmacology Great Iruoghene Edo verfasserin aut In Pharmacological Research - Modern Chinese Medicine Elsevier, 2021 9(2023), Seite 100323- (DE-627)1785333399 26671425 nnns volume:9 year:2023 pages:100323- https://doi.org/10.1016/j.prmcm.2023.100323 kostenfrei https://doaj.org/article/75368af4b2104cc2bc4c6107cccbedb0 kostenfrei http://www.sciencedirect.com/science/article/pii/S2667142523001094 kostenfrei https://doaj.org/toc/2667-1425 Journal toc kostenfrei GBV_USEFLAG_A SYSFLAG_A GBV_DOAJ GBV_ILN_20 GBV_ILN_22 GBV_ILN_23 GBV_ILN_24 GBV_ILN_31 GBV_ILN_39 GBV_ILN_40 GBV_ILN_60 GBV_ILN_62 GBV_ILN_63 GBV_ILN_65 GBV_ILN_69 GBV_ILN_73 GBV_ILN_74 GBV_ILN_95 GBV_ILN_105 GBV_ILN_110 GBV_ILN_151 GBV_ILN_161 GBV_ILN_170 GBV_ILN_206 GBV_ILN_213 GBV_ILN_224 GBV_ILN_230 GBV_ILN_285 GBV_ILN_293 GBV_ILN_602 GBV_ILN_2001 GBV_ILN_2003 GBV_ILN_2005 GBV_ILN_2006 GBV_ILN_2007 GBV_ILN_2008 GBV_ILN_2009 GBV_ILN_2010 GBV_ILN_2011 GBV_ILN_2014 GBV_ILN_2015 GBV_ILN_2020 GBV_ILN_2021 GBV_ILN_2025 GBV_ILN_2026 GBV_ILN_2027 GBV_ILN_2034 GBV_ILN_2038 GBV_ILN_2044 GBV_ILN_2048 GBV_ILN_2049 GBV_ILN_2050 GBV_ILN_2055 GBV_ILN_2056 GBV_ILN_2059 GBV_ILN_2061 GBV_ILN_2064 GBV_ILN_2088 GBV_ILN_2106 GBV_ILN_2110 GBV_ILN_2112 GBV_ILN_2122 GBV_ILN_2129 GBV_ILN_2143 GBV_ILN_2152 GBV_ILN_2153 GBV_ILN_2190 GBV_ILN_2232 GBV_ILN_2336 GBV_ILN_2470 GBV_ILN_2507 GBV_ILN_4012 GBV_ILN_4035 GBV_ILN_4037 GBV_ILN_4112 GBV_ILN_4125 GBV_ILN_4126 GBV_ILN_4242 GBV_ILN_4249 GBV_ILN_4251 GBV_ILN_4305 GBV_ILN_4306 GBV_ILN_4307 GBV_ILN_4313 GBV_ILN_4322 GBV_ILN_4323 GBV_ILN_4324 GBV_ILN_4325 GBV_ILN_4326 GBV_ILN_4333 GBV_ILN_4334 GBV_ILN_4338 GBV_ILN_4367 GBV_ILN_4393 GBV_ILN_4700 AR 9 2023 100323- |
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10.1016/j.prmcm.2023.100323 doi (DE-627)DOAJ099159430 (DE-599)DOAJ75368af4b2104cc2bc4c6107cccbedb0 DE-627 ger DE-627 rakwb eng RZ201-999 RM1-950 Agatha Ngukuran Jikah verfasserin aut Mechanisms of action by sulphur compounds in Allium sativum. A review 2023 Text txt rdacontent Computermedien c rdamedia Online-Ressource cr rdacarrier Background: Allium sativum, the bulbous perennial plant of the Alliaceae family has been utilized as a very valuable remedy in the management of numerous diseases even from time immemorial. The plant exhibits antimicrobial activities over a wide range of microorganisms like parasites, fungi, virus and other pathogens. This broad- spectrum of antimicrobial activity coupled with the low toxicity of Allium sativum are an attraction to scientists and thus it has been vastly employed as a therapeutic cure in contemporary society. The therapeutic properties of Allium sativum (antibacterial, antiviral, fungicidal, anti-cardiovascular disease, anticancer, antidiabetic, anti-blood pressure, antiatherosclerosis, antirheumatic, hyperlipidemia) are linked to the sulphur compounds it contains (diallyl disulfide, allicin, diallyl trisulfide, ajoene's, vinyl-dithiin, micronutrient selenium and S-allylcystein. Objectives: This review considers some sulphur compounds contained in Allium sativum and the mechanisms by which they elicit their biological actions. Method: The journals for this review paper were retrieved from prominent database sources like Academia.edu (https://www.academia.edu), PubMed (https://pubmed.ncbi.nlm.nih.gov/) and Web of science (https://access.clarivate.com). Both medical headings and free text keywords were employed in the search “biological activities of allicin”, “biosynthesis of sulphur compounds in garlic”, “sulphur compounds in garlic”, “mechanism of action of antibacterial action of ajoene”, “S-allylcystein in garlic”, “mechanism of neuroprotection by vinvyl-dithiin”, “anticancer actions of dially disulfide”, mechanism of anti-quorum sensing actions of ajoene, antihyperlipidemic activity of allicin, mechanism of anti-platelet actions of ajoene and other related information from related journals. Results: Allium sativum has many therapeutic properties; antibacterial, neuroprotection, antiviral, fungicidal, lipid metabolism, anti-cardiovascular disease, glucose metabolism, anticancer, antidiabetic, anti-blood pressure, antiatherosclerosis, antirheumatic, hyperlipidemia), these properties result from some sulphur compounds (diallyl disulfide, allicin, diallyl trisulfide, ajoene's, vinyl-dithiin, micronutrient selenium and S-allylcystein) which the plant contains. Conclusion: Within this paper, some sulphur containing phytonutrients in Allium sativum namely; allicin, ajoene, S-allylcystein, vinvyl-dithiin, dially disulfide, dially trisulfide and the mechanisms by which they carry out these actions are considered. The pharmaceutical and food industries have harnessed these phytochemicals in manufacturing both wellness and therapeutic products. Should more research be carried out on Allium sativum, safe and effective doses can be authenticated so that it can be safely included in the management of pathologies. Allium sativum Ajoene Allicin Diallyl disulfide Other systems of medicine Therapeutics. Pharmacology Great Iruoghene Edo verfasserin aut In Pharmacological Research - Modern Chinese Medicine Elsevier, 2021 9(2023), Seite 100323- (DE-627)1785333399 26671425 nnns volume:9 year:2023 pages:100323- https://doi.org/10.1016/j.prmcm.2023.100323 kostenfrei https://doaj.org/article/75368af4b2104cc2bc4c6107cccbedb0 kostenfrei http://www.sciencedirect.com/science/article/pii/S2667142523001094 kostenfrei https://doaj.org/toc/2667-1425 Journal toc kostenfrei GBV_USEFLAG_A SYSFLAG_A GBV_DOAJ GBV_ILN_20 GBV_ILN_22 GBV_ILN_23 GBV_ILN_24 GBV_ILN_31 GBV_ILN_39 GBV_ILN_40 GBV_ILN_60 GBV_ILN_62 GBV_ILN_63 GBV_ILN_65 GBV_ILN_69 GBV_ILN_73 GBV_ILN_74 GBV_ILN_95 GBV_ILN_105 GBV_ILN_110 GBV_ILN_151 GBV_ILN_161 GBV_ILN_170 GBV_ILN_206 GBV_ILN_213 GBV_ILN_224 GBV_ILN_230 GBV_ILN_285 GBV_ILN_293 GBV_ILN_602 GBV_ILN_2001 GBV_ILN_2003 GBV_ILN_2005 GBV_ILN_2006 GBV_ILN_2007 GBV_ILN_2008 GBV_ILN_2009 GBV_ILN_2010 GBV_ILN_2011 GBV_ILN_2014 GBV_ILN_2015 GBV_ILN_2020 GBV_ILN_2021 GBV_ILN_2025 GBV_ILN_2026 GBV_ILN_2027 GBV_ILN_2034 GBV_ILN_2038 GBV_ILN_2044 GBV_ILN_2048 GBV_ILN_2049 GBV_ILN_2050 GBV_ILN_2055 GBV_ILN_2056 GBV_ILN_2059 GBV_ILN_2061 GBV_ILN_2064 GBV_ILN_2088 GBV_ILN_2106 GBV_ILN_2110 GBV_ILN_2112 GBV_ILN_2122 GBV_ILN_2129 GBV_ILN_2143 GBV_ILN_2152 GBV_ILN_2153 GBV_ILN_2190 GBV_ILN_2232 GBV_ILN_2336 GBV_ILN_2470 GBV_ILN_2507 GBV_ILN_4012 GBV_ILN_4035 GBV_ILN_4037 GBV_ILN_4112 GBV_ILN_4125 GBV_ILN_4126 GBV_ILN_4242 GBV_ILN_4249 GBV_ILN_4251 GBV_ILN_4305 GBV_ILN_4306 GBV_ILN_4307 GBV_ILN_4313 GBV_ILN_4322 GBV_ILN_4323 GBV_ILN_4324 GBV_ILN_4325 GBV_ILN_4326 GBV_ILN_4333 GBV_ILN_4334 GBV_ILN_4338 GBV_ILN_4367 GBV_ILN_4393 GBV_ILN_4700 AR 9 2023 100323- |
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10.1016/j.prmcm.2023.100323 doi (DE-627)DOAJ099159430 (DE-599)DOAJ75368af4b2104cc2bc4c6107cccbedb0 DE-627 ger DE-627 rakwb eng RZ201-999 RM1-950 Agatha Ngukuran Jikah verfasserin aut Mechanisms of action by sulphur compounds in Allium sativum. A review 2023 Text txt rdacontent Computermedien c rdamedia Online-Ressource cr rdacarrier Background: Allium sativum, the bulbous perennial plant of the Alliaceae family has been utilized as a very valuable remedy in the management of numerous diseases even from time immemorial. The plant exhibits antimicrobial activities over a wide range of microorganisms like parasites, fungi, virus and other pathogens. This broad- spectrum of antimicrobial activity coupled with the low toxicity of Allium sativum are an attraction to scientists and thus it has been vastly employed as a therapeutic cure in contemporary society. The therapeutic properties of Allium sativum (antibacterial, antiviral, fungicidal, anti-cardiovascular disease, anticancer, antidiabetic, anti-blood pressure, antiatherosclerosis, antirheumatic, hyperlipidemia) are linked to the sulphur compounds it contains (diallyl disulfide, allicin, diallyl trisulfide, ajoene's, vinyl-dithiin, micronutrient selenium and S-allylcystein. Objectives: This review considers some sulphur compounds contained in Allium sativum and the mechanisms by which they elicit their biological actions. Method: The journals for this review paper were retrieved from prominent database sources like Academia.edu (https://www.academia.edu), PubMed (https://pubmed.ncbi.nlm.nih.gov/) and Web of science (https://access.clarivate.com). Both medical headings and free text keywords were employed in the search “biological activities of allicin”, “biosynthesis of sulphur compounds in garlic”, “sulphur compounds in garlic”, “mechanism of action of antibacterial action of ajoene”, “S-allylcystein in garlic”, “mechanism of neuroprotection by vinvyl-dithiin”, “anticancer actions of dially disulfide”, mechanism of anti-quorum sensing actions of ajoene, antihyperlipidemic activity of allicin, mechanism of anti-platelet actions of ajoene and other related information from related journals. Results: Allium sativum has many therapeutic properties; antibacterial, neuroprotection, antiviral, fungicidal, lipid metabolism, anti-cardiovascular disease, glucose metabolism, anticancer, antidiabetic, anti-blood pressure, antiatherosclerosis, antirheumatic, hyperlipidemia), these properties result from some sulphur compounds (diallyl disulfide, allicin, diallyl trisulfide, ajoene's, vinyl-dithiin, micronutrient selenium and S-allylcystein) which the plant contains. Conclusion: Within this paper, some sulphur containing phytonutrients in Allium sativum namely; allicin, ajoene, S-allylcystein, vinvyl-dithiin, dially disulfide, dially trisulfide and the mechanisms by which they carry out these actions are considered. The pharmaceutical and food industries have harnessed these phytochemicals in manufacturing both wellness and therapeutic products. Should more research be carried out on Allium sativum, safe and effective doses can be authenticated so that it can be safely included in the management of pathologies. Allium sativum Ajoene Allicin Diallyl disulfide Other systems of medicine Therapeutics. Pharmacology Great Iruoghene Edo verfasserin aut In Pharmacological Research - Modern Chinese Medicine Elsevier, 2021 9(2023), Seite 100323- (DE-627)1785333399 26671425 nnns volume:9 year:2023 pages:100323- https://doi.org/10.1016/j.prmcm.2023.100323 kostenfrei https://doaj.org/article/75368af4b2104cc2bc4c6107cccbedb0 kostenfrei http://www.sciencedirect.com/science/article/pii/S2667142523001094 kostenfrei https://doaj.org/toc/2667-1425 Journal toc kostenfrei GBV_USEFLAG_A SYSFLAG_A GBV_DOAJ GBV_ILN_20 GBV_ILN_22 GBV_ILN_23 GBV_ILN_24 GBV_ILN_31 GBV_ILN_39 GBV_ILN_40 GBV_ILN_60 GBV_ILN_62 GBV_ILN_63 GBV_ILN_65 GBV_ILN_69 GBV_ILN_73 GBV_ILN_74 GBV_ILN_95 GBV_ILN_105 GBV_ILN_110 GBV_ILN_151 GBV_ILN_161 GBV_ILN_170 GBV_ILN_206 GBV_ILN_213 GBV_ILN_224 GBV_ILN_230 GBV_ILN_285 GBV_ILN_293 GBV_ILN_602 GBV_ILN_2001 GBV_ILN_2003 GBV_ILN_2005 GBV_ILN_2006 GBV_ILN_2007 GBV_ILN_2008 GBV_ILN_2009 GBV_ILN_2010 GBV_ILN_2011 GBV_ILN_2014 GBV_ILN_2015 GBV_ILN_2020 GBV_ILN_2021 GBV_ILN_2025 GBV_ILN_2026 GBV_ILN_2027 GBV_ILN_2034 GBV_ILN_2038 GBV_ILN_2044 GBV_ILN_2048 GBV_ILN_2049 GBV_ILN_2050 GBV_ILN_2055 GBV_ILN_2056 GBV_ILN_2059 GBV_ILN_2061 GBV_ILN_2064 GBV_ILN_2088 GBV_ILN_2106 GBV_ILN_2110 GBV_ILN_2112 GBV_ILN_2122 GBV_ILN_2129 GBV_ILN_2143 GBV_ILN_2152 GBV_ILN_2153 GBV_ILN_2190 GBV_ILN_2232 GBV_ILN_2336 GBV_ILN_2470 GBV_ILN_2507 GBV_ILN_4012 GBV_ILN_4035 GBV_ILN_4037 GBV_ILN_4112 GBV_ILN_4125 GBV_ILN_4126 GBV_ILN_4242 GBV_ILN_4249 GBV_ILN_4251 GBV_ILN_4305 GBV_ILN_4306 GBV_ILN_4307 GBV_ILN_4313 GBV_ILN_4322 GBV_ILN_4323 GBV_ILN_4324 GBV_ILN_4325 GBV_ILN_4326 GBV_ILN_4333 GBV_ILN_4334 GBV_ILN_4338 GBV_ILN_4367 GBV_ILN_4393 GBV_ILN_4700 AR 9 2023 100323- |
| allfieldsSound |
10.1016/j.prmcm.2023.100323 doi (DE-627)DOAJ099159430 (DE-599)DOAJ75368af4b2104cc2bc4c6107cccbedb0 DE-627 ger DE-627 rakwb eng RZ201-999 RM1-950 Agatha Ngukuran Jikah verfasserin aut Mechanisms of action by sulphur compounds in Allium sativum. A review 2023 Text txt rdacontent Computermedien c rdamedia Online-Ressource cr rdacarrier Background: Allium sativum, the bulbous perennial plant of the Alliaceae family has been utilized as a very valuable remedy in the management of numerous diseases even from time immemorial. The plant exhibits antimicrobial activities over a wide range of microorganisms like parasites, fungi, virus and other pathogens. This broad- spectrum of antimicrobial activity coupled with the low toxicity of Allium sativum are an attraction to scientists and thus it has been vastly employed as a therapeutic cure in contemporary society. The therapeutic properties of Allium sativum (antibacterial, antiviral, fungicidal, anti-cardiovascular disease, anticancer, antidiabetic, anti-blood pressure, antiatherosclerosis, antirheumatic, hyperlipidemia) are linked to the sulphur compounds it contains (diallyl disulfide, allicin, diallyl trisulfide, ajoene's, vinyl-dithiin, micronutrient selenium and S-allylcystein. Objectives: This review considers some sulphur compounds contained in Allium sativum and the mechanisms by which they elicit their biological actions. Method: The journals for this review paper were retrieved from prominent database sources like Academia.edu (https://www.academia.edu), PubMed (https://pubmed.ncbi.nlm.nih.gov/) and Web of science (https://access.clarivate.com). Both medical headings and free text keywords were employed in the search “biological activities of allicin”, “biosynthesis of sulphur compounds in garlic”, “sulphur compounds in garlic”, “mechanism of action of antibacterial action of ajoene”, “S-allylcystein in garlic”, “mechanism of neuroprotection by vinvyl-dithiin”, “anticancer actions of dially disulfide”, mechanism of anti-quorum sensing actions of ajoene, antihyperlipidemic activity of allicin, mechanism of anti-platelet actions of ajoene and other related information from related journals. Results: Allium sativum has many therapeutic properties; antibacterial, neuroprotection, antiviral, fungicidal, lipid metabolism, anti-cardiovascular disease, glucose metabolism, anticancer, antidiabetic, anti-blood pressure, antiatherosclerosis, antirheumatic, hyperlipidemia), these properties result from some sulphur compounds (diallyl disulfide, allicin, diallyl trisulfide, ajoene's, vinyl-dithiin, micronutrient selenium and S-allylcystein) which the plant contains. Conclusion: Within this paper, some sulphur containing phytonutrients in Allium sativum namely; allicin, ajoene, S-allylcystein, vinvyl-dithiin, dially disulfide, dially trisulfide and the mechanisms by which they carry out these actions are considered. The pharmaceutical and food industries have harnessed these phytochemicals in manufacturing both wellness and therapeutic products. Should more research be carried out on Allium sativum, safe and effective doses can be authenticated so that it can be safely included in the management of pathologies. Allium sativum Ajoene Allicin Diallyl disulfide Other systems of medicine Therapeutics. Pharmacology Great Iruoghene Edo verfasserin aut In Pharmacological Research - Modern Chinese Medicine Elsevier, 2021 9(2023), Seite 100323- (DE-627)1785333399 26671425 nnns volume:9 year:2023 pages:100323- https://doi.org/10.1016/j.prmcm.2023.100323 kostenfrei https://doaj.org/article/75368af4b2104cc2bc4c6107cccbedb0 kostenfrei http://www.sciencedirect.com/science/article/pii/S2667142523001094 kostenfrei https://doaj.org/toc/2667-1425 Journal toc kostenfrei GBV_USEFLAG_A SYSFLAG_A GBV_DOAJ GBV_ILN_20 GBV_ILN_22 GBV_ILN_23 GBV_ILN_24 GBV_ILN_31 GBV_ILN_39 GBV_ILN_40 GBV_ILN_60 GBV_ILN_62 GBV_ILN_63 GBV_ILN_65 GBV_ILN_69 GBV_ILN_73 GBV_ILN_74 GBV_ILN_95 GBV_ILN_105 GBV_ILN_110 GBV_ILN_151 GBV_ILN_161 GBV_ILN_170 GBV_ILN_206 GBV_ILN_213 GBV_ILN_224 GBV_ILN_230 GBV_ILN_285 GBV_ILN_293 GBV_ILN_602 GBV_ILN_2001 GBV_ILN_2003 GBV_ILN_2005 GBV_ILN_2006 GBV_ILN_2007 GBV_ILN_2008 GBV_ILN_2009 GBV_ILN_2010 GBV_ILN_2011 GBV_ILN_2014 GBV_ILN_2015 GBV_ILN_2020 GBV_ILN_2021 GBV_ILN_2025 GBV_ILN_2026 GBV_ILN_2027 GBV_ILN_2034 GBV_ILN_2038 GBV_ILN_2044 GBV_ILN_2048 GBV_ILN_2049 GBV_ILN_2050 GBV_ILN_2055 GBV_ILN_2056 GBV_ILN_2059 GBV_ILN_2061 GBV_ILN_2064 GBV_ILN_2088 GBV_ILN_2106 GBV_ILN_2110 GBV_ILN_2112 GBV_ILN_2122 GBV_ILN_2129 GBV_ILN_2143 GBV_ILN_2152 GBV_ILN_2153 GBV_ILN_2190 GBV_ILN_2232 GBV_ILN_2336 GBV_ILN_2470 GBV_ILN_2507 GBV_ILN_4012 GBV_ILN_4035 GBV_ILN_4037 GBV_ILN_4112 GBV_ILN_4125 GBV_ILN_4126 GBV_ILN_4242 GBV_ILN_4249 GBV_ILN_4251 GBV_ILN_4305 GBV_ILN_4306 GBV_ILN_4307 GBV_ILN_4313 GBV_ILN_4322 GBV_ILN_4323 GBV_ILN_4324 GBV_ILN_4325 GBV_ILN_4326 GBV_ILN_4333 GBV_ILN_4334 GBV_ILN_4338 GBV_ILN_4367 GBV_ILN_4393 GBV_ILN_4700 AR 9 2023 100323- |
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A review</subfield></datafield><datafield tag="264" ind1=" " ind2="1"><subfield code="c">2023</subfield></datafield><datafield tag="336" ind1=" " ind2=" "><subfield code="a">Text</subfield><subfield code="b">txt</subfield><subfield code="2">rdacontent</subfield></datafield><datafield tag="337" ind1=" " ind2=" "><subfield code="a">Computermedien</subfield><subfield code="b">c</subfield><subfield code="2">rdamedia</subfield></datafield><datafield tag="338" ind1=" " ind2=" "><subfield code="a">Online-Ressource</subfield><subfield code="b">cr</subfield><subfield code="2">rdacarrier</subfield></datafield><datafield tag="520" ind1=" " ind2=" "><subfield code="a">Background: Allium sativum, the bulbous perennial plant of the Alliaceae family has been utilized as a very valuable remedy in the management of numerous diseases even from time immemorial. The plant exhibits antimicrobial activities over a wide range of microorganisms like parasites, fungi, virus and other pathogens. This broad- spectrum of antimicrobial activity coupled with the low toxicity of Allium sativum are an attraction to scientists and thus it has been vastly employed as a therapeutic cure in contemporary society. The therapeutic properties of Allium sativum (antibacterial, antiviral, fungicidal, anti-cardiovascular disease, anticancer, antidiabetic, anti-blood pressure, antiatherosclerosis, antirheumatic, hyperlipidemia) are linked to the sulphur compounds it contains (diallyl disulfide, allicin, diallyl trisulfide, ajoene's, vinyl-dithiin, micronutrient selenium and S-allylcystein. Objectives: This review considers some sulphur compounds contained in Allium sativum and the mechanisms by which they elicit their biological actions. Method: The journals for this review paper were retrieved from prominent database sources like Academia.edu (https://www.academia.edu), PubMed (https://pubmed.ncbi.nlm.nih.gov/) and Web of science (https://access.clarivate.com). Both medical headings and free text keywords were employed in the search “biological activities of allicin”, “biosynthesis of sulphur compounds in garlic”, “sulphur compounds in garlic”, “mechanism of action of antibacterial action of ajoene”, “S-allylcystein in garlic”, “mechanism of neuroprotection by vinvyl-dithiin”, “anticancer actions of dially disulfide”, mechanism of anti-quorum sensing actions of ajoene, antihyperlipidemic activity of allicin, mechanism of anti-platelet actions of ajoene and other related information from related journals. Results: Allium sativum has many therapeutic properties; antibacterial, neuroprotection, antiviral, fungicidal, lipid metabolism, anti-cardiovascular disease, glucose metabolism, anticancer, antidiabetic, anti-blood pressure, antiatherosclerosis, antirheumatic, hyperlipidemia), these properties result from some sulphur compounds (diallyl disulfide, allicin, diallyl trisulfide, ajoene's, vinyl-dithiin, micronutrient selenium and S-allylcystein) which the plant contains. Conclusion: Within this paper, some sulphur containing phytonutrients in Allium sativum namely; allicin, ajoene, S-allylcystein, vinvyl-dithiin, dially disulfide, dially trisulfide and the mechanisms by which they carry out these actions are considered. The pharmaceutical and food industries have harnessed these phytochemicals in manufacturing both wellness and therapeutic products. 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Agatha Ngukuran Jikah |
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Agatha Ngukuran Jikah misc RZ201-999 misc RM1-950 misc Allium sativum misc Ajoene misc Allicin misc Diallyl disulfide misc Other systems of medicine misc Therapeutics. Pharmacology Mechanisms of action by sulphur compounds in Allium sativum. A review |
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RZ201-999 RM1-950 Mechanisms of action by sulphur compounds in Allium sativum. A review Allium sativum Ajoene Allicin Diallyl disulfide |
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misc RZ201-999 misc RM1-950 misc Allium sativum misc Ajoene misc Allicin misc Diallyl disulfide misc Other systems of medicine misc Therapeutics. Pharmacology |
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mechanisms of action by sulphur compounds in allium sativum. a review |
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Mechanisms of action by sulphur compounds in Allium sativum. A review |
| abstract |
Background: Allium sativum, the bulbous perennial plant of the Alliaceae family has been utilized as a very valuable remedy in the management of numerous diseases even from time immemorial. The plant exhibits antimicrobial activities over a wide range of microorganisms like parasites, fungi, virus and other pathogens. This broad- spectrum of antimicrobial activity coupled with the low toxicity of Allium sativum are an attraction to scientists and thus it has been vastly employed as a therapeutic cure in contemporary society. The therapeutic properties of Allium sativum (antibacterial, antiviral, fungicidal, anti-cardiovascular disease, anticancer, antidiabetic, anti-blood pressure, antiatherosclerosis, antirheumatic, hyperlipidemia) are linked to the sulphur compounds it contains (diallyl disulfide, allicin, diallyl trisulfide, ajoene's, vinyl-dithiin, micronutrient selenium and S-allylcystein. Objectives: This review considers some sulphur compounds contained in Allium sativum and the mechanisms by which they elicit their biological actions. Method: The journals for this review paper were retrieved from prominent database sources like Academia.edu (https://www.academia.edu), PubMed (https://pubmed.ncbi.nlm.nih.gov/) and Web of science (https://access.clarivate.com). Both medical headings and free text keywords were employed in the search “biological activities of allicin”, “biosynthesis of sulphur compounds in garlic”, “sulphur compounds in garlic”, “mechanism of action of antibacterial action of ajoene”, “S-allylcystein in garlic”, “mechanism of neuroprotection by vinvyl-dithiin”, “anticancer actions of dially disulfide”, mechanism of anti-quorum sensing actions of ajoene, antihyperlipidemic activity of allicin, mechanism of anti-platelet actions of ajoene and other related information from related journals. Results: Allium sativum has many therapeutic properties; antibacterial, neuroprotection, antiviral, fungicidal, lipid metabolism, anti-cardiovascular disease, glucose metabolism, anticancer, antidiabetic, anti-blood pressure, antiatherosclerosis, antirheumatic, hyperlipidemia), these properties result from some sulphur compounds (diallyl disulfide, allicin, diallyl trisulfide, ajoene's, vinyl-dithiin, micronutrient selenium and S-allylcystein) which the plant contains. Conclusion: Within this paper, some sulphur containing phytonutrients in Allium sativum namely; allicin, ajoene, S-allylcystein, vinvyl-dithiin, dially disulfide, dially trisulfide and the mechanisms by which they carry out these actions are considered. The pharmaceutical and food industries have harnessed these phytochemicals in manufacturing both wellness and therapeutic products. Should more research be carried out on Allium sativum, safe and effective doses can be authenticated so that it can be safely included in the management of pathologies. |
| abstractGer |
Background: Allium sativum, the bulbous perennial plant of the Alliaceae family has been utilized as a very valuable remedy in the management of numerous diseases even from time immemorial. The plant exhibits antimicrobial activities over a wide range of microorganisms like parasites, fungi, virus and other pathogens. This broad- spectrum of antimicrobial activity coupled with the low toxicity of Allium sativum are an attraction to scientists and thus it has been vastly employed as a therapeutic cure in contemporary society. The therapeutic properties of Allium sativum (antibacterial, antiviral, fungicidal, anti-cardiovascular disease, anticancer, antidiabetic, anti-blood pressure, antiatherosclerosis, antirheumatic, hyperlipidemia) are linked to the sulphur compounds it contains (diallyl disulfide, allicin, diallyl trisulfide, ajoene's, vinyl-dithiin, micronutrient selenium and S-allylcystein. Objectives: This review considers some sulphur compounds contained in Allium sativum and the mechanisms by which they elicit their biological actions. Method: The journals for this review paper were retrieved from prominent database sources like Academia.edu (https://www.academia.edu), PubMed (https://pubmed.ncbi.nlm.nih.gov/) and Web of science (https://access.clarivate.com). Both medical headings and free text keywords were employed in the search “biological activities of allicin”, “biosynthesis of sulphur compounds in garlic”, “sulphur compounds in garlic”, “mechanism of action of antibacterial action of ajoene”, “S-allylcystein in garlic”, “mechanism of neuroprotection by vinvyl-dithiin”, “anticancer actions of dially disulfide”, mechanism of anti-quorum sensing actions of ajoene, antihyperlipidemic activity of allicin, mechanism of anti-platelet actions of ajoene and other related information from related journals. Results: Allium sativum has many therapeutic properties; antibacterial, neuroprotection, antiviral, fungicidal, lipid metabolism, anti-cardiovascular disease, glucose metabolism, anticancer, antidiabetic, anti-blood pressure, antiatherosclerosis, antirheumatic, hyperlipidemia), these properties result from some sulphur compounds (diallyl disulfide, allicin, diallyl trisulfide, ajoene's, vinyl-dithiin, micronutrient selenium and S-allylcystein) which the plant contains. Conclusion: Within this paper, some sulphur containing phytonutrients in Allium sativum namely; allicin, ajoene, S-allylcystein, vinvyl-dithiin, dially disulfide, dially trisulfide and the mechanisms by which they carry out these actions are considered. The pharmaceutical and food industries have harnessed these phytochemicals in manufacturing both wellness and therapeutic products. Should more research be carried out on Allium sativum, safe and effective doses can be authenticated so that it can be safely included in the management of pathologies. |
| abstract_unstemmed |
Background: Allium sativum, the bulbous perennial plant of the Alliaceae family has been utilized as a very valuable remedy in the management of numerous diseases even from time immemorial. The plant exhibits antimicrobial activities over a wide range of microorganisms like parasites, fungi, virus and other pathogens. This broad- spectrum of antimicrobial activity coupled with the low toxicity of Allium sativum are an attraction to scientists and thus it has been vastly employed as a therapeutic cure in contemporary society. The therapeutic properties of Allium sativum (antibacterial, antiviral, fungicidal, anti-cardiovascular disease, anticancer, antidiabetic, anti-blood pressure, antiatherosclerosis, antirheumatic, hyperlipidemia) are linked to the sulphur compounds it contains (diallyl disulfide, allicin, diallyl trisulfide, ajoene's, vinyl-dithiin, micronutrient selenium and S-allylcystein. Objectives: This review considers some sulphur compounds contained in Allium sativum and the mechanisms by which they elicit their biological actions. Method: The journals for this review paper were retrieved from prominent database sources like Academia.edu (https://www.academia.edu), PubMed (https://pubmed.ncbi.nlm.nih.gov/) and Web of science (https://access.clarivate.com). Both medical headings and free text keywords were employed in the search “biological activities of allicin”, “biosynthesis of sulphur compounds in garlic”, “sulphur compounds in garlic”, “mechanism of action of antibacterial action of ajoene”, “S-allylcystein in garlic”, “mechanism of neuroprotection by vinvyl-dithiin”, “anticancer actions of dially disulfide”, mechanism of anti-quorum sensing actions of ajoene, antihyperlipidemic activity of allicin, mechanism of anti-platelet actions of ajoene and other related information from related journals. Results: Allium sativum has many therapeutic properties; antibacterial, neuroprotection, antiviral, fungicidal, lipid metabolism, anti-cardiovascular disease, glucose metabolism, anticancer, antidiabetic, anti-blood pressure, antiatherosclerosis, antirheumatic, hyperlipidemia), these properties result from some sulphur compounds (diallyl disulfide, allicin, diallyl trisulfide, ajoene's, vinyl-dithiin, micronutrient selenium and S-allylcystein) which the plant contains. Conclusion: Within this paper, some sulphur containing phytonutrients in Allium sativum namely; allicin, ajoene, S-allylcystein, vinvyl-dithiin, dially disulfide, dially trisulfide and the mechanisms by which they carry out these actions are considered. The pharmaceutical and food industries have harnessed these phytochemicals in manufacturing both wellness and therapeutic products. Should more research be carried out on Allium sativum, safe and effective doses can be authenticated so that it can be safely included in the management of pathologies. |
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Mechanisms of action by sulphur compounds in Allium sativum. A review |
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https://doi.org/10.1016/j.prmcm.2023.100323 https://doaj.org/article/75368af4b2104cc2bc4c6107cccbedb0 http://www.sciencedirect.com/science/article/pii/S2667142523001094 https://doaj.org/toc/2667-1425 |
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2024-07-03T21:20:50.933Z |
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