Clinical and Biological Validation of an Allogeneous Cancellous Bone Block for Alveolar Maxillary Ridge Reconstruction: A Case Series

This exploratory case series clinically and histologically investigated the performance of allogeneic cancellous freeze-dried bone allograft (FDBA) bone blocks (Maxgraft<sup<®</sup<) for the lateral augmentation of local alveolar defects in the posterior maxilla as part of two-staged imp...
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Autor*in:	Alexandre Perez [verfasserIn] Elena Pierantozzi [verfasserIn] Roberto Di Felice [verfasserIn] Tommaso Lombardi [verfasserIn]

Format:	E-Artikel
Sprache:	Englisch

Erschienen:	2024

Schlagwörter:	block augmentation lateral augmentation allograft human histology Maxgraft bone block

Übergeordnetes Werk:	In: Dentistry Journal - MDPI AG, 2013, 12(2024), 2, p 42
Übergeordnetes Werk:	volume:12 ; year:2024 ; number:2, p 42

Links:	Link aufrufen Link aufrufen Link aufrufen Journal toc

DOI / URN:	10.3390/dj12020042

Katalog-ID:	DOAJ099654954

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language	English
source	In Dentistry Journal 12(2024), 2, p 42 volume:12 year:2024 number:2, p 42
sourceStr	In Dentistry Journal 12(2024), 2, p 42 volume:12 year:2024 number:2, p 42
format_phy_str_mv	Article
institution	findex.gbv.de
topic_facet	block augmentation lateral augmentation allograft human histology Maxgraft bone block Dentistry
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container_title	Dentistry Journal
authorswithroles_txt_mv	Alexandre Perez @@aut@@ Elena Pierantozzi @@aut@@ Roberto Di Felice @@aut@@ Tommaso Lombardi @@aut@@
publishDateDaySort_date	2024-01-01T00:00:00Z
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callnumber-first	R - Medicine
author	Alexandre Perez
spellingShingle	Alexandre Perez misc RK1-715 misc block augmentation misc lateral augmentation misc allograft misc human histology misc Maxgraft misc bone block misc Dentistry Clinical and Biological Validation of an Allogeneous Cancellous Bone Block for Alveolar Maxillary Ridge Reconstruction: A Case Series
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topic_title	RK1-715 Clinical and Biological Validation of an Allogeneous Cancellous Bone Block for Alveolar Maxillary Ridge Reconstruction: A Case Series block augmentation lateral augmentation allograft human histology Maxgraft bone block
topic	misc RK1-715 misc block augmentation misc lateral augmentation misc allograft misc human histology misc Maxgraft misc bone block misc Dentistry
topic_unstemmed	misc RK1-715 misc block augmentation misc lateral augmentation misc allograft misc human histology misc Maxgraft misc bone block misc Dentistry
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title	Clinical and Biological Validation of an Allogeneous Cancellous Bone Block for Alveolar Maxillary Ridge Reconstruction: A Case Series
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title_full	Clinical and Biological Validation of an Allogeneous Cancellous Bone Block for Alveolar Maxillary Ridge Reconstruction: A Case Series
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title_sort	clinical and biological validation of an allogeneous cancellous bone block for alveolar maxillary ridge reconstruction: a case series
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title_auth	Clinical and Biological Validation of an Allogeneous Cancellous Bone Block for Alveolar Maxillary Ridge Reconstruction: A Case Series
abstract	This exploratory case series clinically and histologically investigated the performance of allogeneic cancellous freeze-dried bone allograft (FDBA) bone blocks (Maxgraft<sup<®</sup<) for the lateral augmentation of local alveolar defects in the posterior maxilla as part of two-staged implant therapy. Five patients receiving eight implants 5 months after block augmentation with a follow-up period of up to 3 years were documented and analyzed. Horizontal alveolar dimensions before and 5 months after block augmentation were quantified using CBCT. Radiographic marginal bone level changes were quantified at implant placement, loading, and 1 year post-placement. Graft integration and resorption were histologically qualitatively evaluated from core biopsies retrieved at implant placement. Block augmentations resulted in a pronounced horizontal median bone gain of 7.0 (5.5 to 7.8) mm. Marginal implant bone levels in block-augmented bone remained constant over the 1 year follow-up period. Block grafts appeared histologically well integrated. Histologic analysis also revealed signs of progressive resorption and new bone formation at the lateral aspects of the grafts. The results of this case series support using Maxgraft<sup<®</sup< cancellous FDBA blocks as suitable materials for the lateral augmentation of local alveolar defects.
abstractGer	This exploratory case series clinically and histologically investigated the performance of allogeneic cancellous freeze-dried bone allograft (FDBA) bone blocks (Maxgraft<sup<®</sup<) for the lateral augmentation of local alveolar defects in the posterior maxilla as part of two-staged implant therapy. Five patients receiving eight implants 5 months after block augmentation with a follow-up period of up to 3 years were documented and analyzed. Horizontal alveolar dimensions before and 5 months after block augmentation were quantified using CBCT. Radiographic marginal bone level changes were quantified at implant placement, loading, and 1 year post-placement. Graft integration and resorption were histologically qualitatively evaluated from core biopsies retrieved at implant placement. Block augmentations resulted in a pronounced horizontal median bone gain of 7.0 (5.5 to 7.8) mm. Marginal implant bone levels in block-augmented bone remained constant over the 1 year follow-up period. Block grafts appeared histologically well integrated. Histologic analysis also revealed signs of progressive resorption and new bone formation at the lateral aspects of the grafts. The results of this case series support using Maxgraft<sup<®</sup< cancellous FDBA blocks as suitable materials for the lateral augmentation of local alveolar defects.
abstract_unstemmed	This exploratory case series clinically and histologically investigated the performance of allogeneic cancellous freeze-dried bone allograft (FDBA) bone blocks (Maxgraft<sup<®</sup<) for the lateral augmentation of local alveolar defects in the posterior maxilla as part of two-staged implant therapy. Five patients receiving eight implants 5 months after block augmentation with a follow-up period of up to 3 years were documented and analyzed. Horizontal alveolar dimensions before and 5 months after block augmentation were quantified using CBCT. Radiographic marginal bone level changes were quantified at implant placement, loading, and 1 year post-placement. Graft integration and resorption were histologically qualitatively evaluated from core biopsies retrieved at implant placement. Block augmentations resulted in a pronounced horizontal median bone gain of 7.0 (5.5 to 7.8) mm. Marginal implant bone levels in block-augmented bone remained constant over the 1 year follow-up period. Block grafts appeared histologically well integrated. Histologic analysis also revealed signs of progressive resorption and new bone formation at the lateral aspects of the grafts. The results of this case series support using Maxgraft<sup<®</sup< cancellous FDBA blocks as suitable materials for the lateral augmentation of local alveolar defects.
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title_short	Clinical and Biological Validation of an Allogeneous Cancellous Bone Block for Alveolar Maxillary Ridge Reconstruction: A Case Series
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Clinical and Biological Validation of an Allogeneous Cancellous Bone Block for Alveolar Maxillary Ridge Reconstruction: A Case Series

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