The Prognostic Value of Olfactory Dysfunction in Patients with COVID-19: The COVIDORA Study
Background: Among all studies describing COVID-19 clinical features during the first wave of the pandemic, only a few retrospective studies have assessed the correlation between olfac-tory dysfunction (OD) and the evolution of disease severity. The main aim was to assess whether OD is a predictive f...
Ausführliche Beschreibung
Gespeichert in:
| Format: |
E-Artikel |
|---|---|
| Sprache: |
Englisch |
| Erschienen: |
2024 |
|---|
| Schlagwörter: |
|---|
| Übergeordnetes Werk: |
In: Life - MDPI AG, 2012, 14(2024), 3, p 293 |
|---|---|
| Übergeordnetes Werk: |
volume:14 ; year:2024 ; number:3, p 293 |
| Links: |
|---|
| DOI / URN: |
10.3390/life14030293 |
|---|
| Katalog-ID: |
DOAJ100475892 |
|---|
| LEADER | 01000naa a22002652 4500 | ||
|---|---|---|---|
| 001 | DOAJ100475892 | ||
| 003 | DE-627 | ||
| 005 | 20240414095808.0 | ||
| 007 | cr uuu---uuuuu | ||
| 008 | 240414s2024 xx |||||o 00| ||eng c | ||
| 024 | 7 | |a 10.3390/life14030293 |2 doi | |
| 035 | |a (DE-627)DOAJ100475892 | ||
| 035 | |a (DE-599)DOAJ483e5d4d89164fbeb9f78d1f473bbd59 | ||
| 040 | |a DE-627 |b ger |c DE-627 |e rakwb | ||
| 041 | |a eng | ||
| 100 | 0 | |a Anne-Laure Hamel |e verfasserin |4 aut | |
| 245 | 1 | 4 | |a The Prognostic Value of Olfactory Dysfunction in Patients with COVID-19: The COVIDORA Study |
| 264 | 1 | |c 2024 | |
| 336 | |a Text |b txt |2 rdacontent | ||
| 337 | |a Computermedien |b c |2 rdamedia | ||
| 338 | |a Online-Ressource |b cr |2 rdacarrier | ||
| 520 | |a Background: Among all studies describing COVID-19 clinical features during the first wave of the pandemic, only a few retrospective studies have assessed the correlation between olfac-tory dysfunction (OD) and the evolution of disease severity. The main aim was to assess whether OD is a predictive factor of COVID-19 severity based on the patient’s medical management (outpa-tient care, standard hospital admission, and ICU admission). Methods: A national, prospective, mul-ticenter cohort study was conducted in 20 public hospitals and a public center for COVID-19 screen-ing. During the first wave of the pandemic, from 6 April to 11 May 2020, all patients tested positive for COVID-19 confirmed by RT-PCR underwent two follow-up ENT consultations within 10 days of symptom onset. The main outcome measures were the evolution of medical management (out-patient care, standard hospital admission, and ICU admission) at diagnosis and along the clinical course of COVID-19 disease. Results: Among 481 patients included, the prevalence of OD was 60.7%, and it affected mostly female patients (74.3%) under 65 years old (92.5%), with fewer comor-bidities than patients with normal olfactory function. Here, 99.3% (290/292) of patients with OD presented with non-severe COVID-19 disease. Patients reporting OD were significantly less hospi-talized than the ones managed as outpatients, in either a standard medical unit or an ICU. Conclu-sions: As regards the clinical course of COVID-19 disease, OD could predict a decreased risk of hospitalization during the first wave of the pandemic. | ||
| 650 | 4 | |a olfactory dysfunction | |
| 650 | 4 | |a anosmia | |
| 650 | 4 | |a phantosmia | |
| 650 | 4 | |a parosmia | |
| 650 | 4 | |a COVID-19 | |
| 650 | 4 | |a taste dysfunction | |
| 653 | 0 | |a Science | |
| 653 | 0 | |a Q | |
| 700 | 0 | |a Léo Delbos |e verfasserin |4 aut | |
| 700 | 0 | |a Pierre-André Natella |e verfasserin |4 aut | |
| 700 | 0 | |a Thomas Radulesco |e verfasserin |4 aut | |
| 700 | 0 | |a Mihaela Alexandru |e verfasserin |4 aut | |
| 700 | 0 | |a Emmanuel Bartaire |e verfasserin |4 aut | |
| 700 | 0 | |a Sophie Bartier |e verfasserin |4 aut | |
| 700 | 0 | |a Gonda Benoite |e verfasserin |4 aut | |
| 700 | 0 | |a Emilie Bequignon |e verfasserin |4 aut | |
| 700 | 0 | |a Laurent Castillo |e verfasserin |4 aut | |
| 700 | 0 | |a Florence Canouï-Poitrine |e verfasserin |4 aut | |
| 700 | 0 | |a Florent Carsuzaa |e verfasserin |4 aut | |
| 700 | 0 | |a Alain Corré |e verfasserin |4 aut | |
| 700 | 0 | |a André Coste |e verfasserin |4 aut | |
| 700 | 0 | |a Vincent Couloigner |e verfasserin |4 aut | |
| 700 | 0 | |a Clémentine Daveau |e verfasserin |4 aut | |
| 700 | 0 | |a Paul De Boissieu |e verfasserin |4 aut | |
| 700 | 0 | |a Guillaume De Bonnecaze |e verfasserin |4 aut | |
| 700 | 0 | |a Ludovic De Gabory |e verfasserin |4 aut | |
| 700 | 0 | |a Christian Debry |e verfasserin |4 aut | |
| 700 | 0 | |a Simon Deraedt |e verfasserin |4 aut | |
| 700 | 0 | |a Xavier Dufour |e verfasserin |4 aut | |
| 700 | 0 | |a Wissame El Bakkouri |e verfasserin |4 aut | |
| 700 | 0 | |a Laurent Gilain |e verfasserin |4 aut | |
| 700 | 0 | |a Stéphane Hans |e verfasserin |4 aut | |
| 700 | 0 | |a Charlotte Hautefort |e verfasserin |4 aut | |
| 700 | 0 | |a Ruben Hermann |e verfasserin |4 aut | |
| 700 | 0 | |a Roger Jankowski |e verfasserin |4 aut | |
| 700 | 0 | |a Candice La Croix |e verfasserin |4 aut | |
| 700 | 0 | |a Jean-Baptiste Lecanu |e verfasserin |4 aut | |
| 700 | 0 | |a Olivier Malard |e verfasserin |4 aut | |
| 700 | 0 | |a Justin Michel |e verfasserin |4 aut | |
| 700 | 0 | |a Yann Nguyen |e verfasserin |4 aut | |
| 700 | 0 | |a Jerome Nevoux |e verfasserin |4 aut | |
| 700 | 0 | |a Jean-François Papon |e verfasserin |4 aut | |
| 700 | 0 | |a Vincent Patron |e verfasserin |4 aut | |
| 700 | 0 | |a Marine Prigent |e verfasserin |4 aut | |
| 700 | 0 | |a Virginie Pruliere-Escabasse |e verfasserin |4 aut | |
| 700 | 0 | |a Marion Renaud |e verfasserin |4 aut | |
| 700 | 0 | |a Cécile Rumeau |e verfasserin |4 aut | |
| 700 | 0 | |a Dominique Salmon |e verfasserin |4 aut | |
| 700 | 0 | |a Nicolas Saroul |e verfasserin |4 aut | |
| 700 | 0 | |a Elie Serrano |e verfasserin |4 aut | |
| 700 | 0 | |a Christine Nhung Tran Khai |e verfasserin |4 aut | |
| 700 | 0 | |a Stéphane Tringali |e verfasserin |4 aut | |
| 700 | 0 | |a Eric Truy |e verfasserin |4 aut | |
| 700 | 0 | |a Clair Vandersteen |e verfasserin |4 aut | |
| 700 | 0 | |a Benjamin Verillaud |e verfasserin |4 aut | |
| 700 | 0 | |a Raphaël Veil |e verfasserin |4 aut | |
| 700 | 0 | |a Maxime Fieux |e verfasserin |4 aut | |
| 773 | 0 | 8 | |i In |t Life |d MDPI AG, 2012 |g 14(2024), 3, p 293 |w (DE-627)718627156 |w (DE-600)2662250-6 |x 20751729 |7 nnns |
| 773 | 1 | 8 | |g volume:14 |g year:2024 |g number:3, p 293 |
| 856 | 4 | 0 | |u https://doi.org/10.3390/life14030293 |z kostenfrei |
| 856 | 4 | 0 | |u https://doaj.org/article/483e5d4d89164fbeb9f78d1f473bbd59 |z kostenfrei |
| 856 | 4 | 0 | |u https://www.mdpi.com/2075-1729/14/3/293 |z kostenfrei |
| 856 | 4 | 2 | |u https://doaj.org/toc/2075-1729 |y Journal toc |z kostenfrei |
| 912 | |a GBV_USEFLAG_A | ||
| 912 | |a SYSFLAG_A | ||
| 912 | |a GBV_DOAJ | ||
| 912 | |a GBV_ILN_20 | ||
| 912 | |a GBV_ILN_22 | ||
| 912 | |a GBV_ILN_23 | ||
| 912 | |a GBV_ILN_24 | ||
| 912 | |a GBV_ILN_31 | ||
| 912 | |a GBV_ILN_39 | ||
| 912 | |a GBV_ILN_40 | ||
| 912 | |a GBV_ILN_62 | ||
| 912 | |a GBV_ILN_63 | ||
| 912 | |a GBV_ILN_65 | ||
| 912 | |a GBV_ILN_69 | ||
| 912 | |a GBV_ILN_70 | ||
| 912 | |a GBV_ILN_73 | ||
| 912 | |a GBV_ILN_74 | ||
| 912 | |a GBV_ILN_95 | ||
| 912 | |a GBV_ILN_105 | ||
| 912 | |a GBV_ILN_110 | ||
| 912 | |a GBV_ILN_151 | ||
| 912 | |a GBV_ILN_161 | ||
| 912 | |a GBV_ILN_170 | ||
| 912 | |a GBV_ILN_206 | ||
| 912 | |a GBV_ILN_213 | ||
| 912 | |a GBV_ILN_230 | ||
| 912 | |a GBV_ILN_285 | ||
| 912 | |a GBV_ILN_293 | ||
| 912 | |a GBV_ILN_602 | ||
| 912 | |a GBV_ILN_2005 | ||
| 912 | |a GBV_ILN_2009 | ||
| 912 | |a GBV_ILN_2011 | ||
| 912 | |a GBV_ILN_2014 | ||
| 912 | |a GBV_ILN_2055 | ||
| 912 | |a GBV_ILN_2111 | ||
| 912 | |a GBV_ILN_4012 | ||
| 912 | |a GBV_ILN_4037 | ||
| 912 | |a GBV_ILN_4112 | ||
| 912 | |a GBV_ILN_4125 | ||
| 912 | |a GBV_ILN_4126 | ||
| 912 | |a GBV_ILN_4249 | ||
| 912 | |a GBV_ILN_4305 | ||
| 912 | |a GBV_ILN_4306 | ||
| 912 | |a GBV_ILN_4307 | ||
| 912 | |a GBV_ILN_4313 | ||
| 912 | |a GBV_ILN_4322 | ||
| 912 | |a GBV_ILN_4323 | ||
| 912 | |a GBV_ILN_4324 | ||
| 912 | |a GBV_ILN_4325 | ||
| 912 | |a GBV_ILN_4338 | ||
| 912 | |a GBV_ILN_4367 | ||
| 912 | |a GBV_ILN_4700 | ||
| 951 | |a AR | ||
| 952 | |d 14 |j 2024 |e 3, p 293 | ||
| author_variant |
a l h alh l d ld p a n pan t r tr m a ma e b eb s b sb g b gb e b eb l c lc f c p fcp f c fc a c ac a c ac v c vc c d cd p d b pdb g d b gdb l d g ldg c d cd s d sd x d xd w e b web l g lg s h sh c h ch r h rh r j rj c l c clc j b l jbl o m om j m jm y n yn j n jn j f p jfp v p vp m p mp v p e vpe m r mr c r cr d s ds n s ns e s es c n t k cntk s t st e t et c v cv b v bv r v rv m f mf |
|---|---|
| matchkey_str |
article:20751729:2024----::hponsivleflatrdsucinnainsiho |
| hierarchy_sort_str |
2024 |
| publishDate |
2024 |
| allfields |
10.3390/life14030293 doi (DE-627)DOAJ100475892 (DE-599)DOAJ483e5d4d89164fbeb9f78d1f473bbd59 DE-627 ger DE-627 rakwb eng Anne-Laure Hamel verfasserin aut The Prognostic Value of Olfactory Dysfunction in Patients with COVID-19: The COVIDORA Study 2024 Text txt rdacontent Computermedien c rdamedia Online-Ressource cr rdacarrier Background: Among all studies describing COVID-19 clinical features during the first wave of the pandemic, only a few retrospective studies have assessed the correlation between olfac-tory dysfunction (OD) and the evolution of disease severity. The main aim was to assess whether OD is a predictive factor of COVID-19 severity based on the patient’s medical management (outpa-tient care, standard hospital admission, and ICU admission). Methods: A national, prospective, mul-ticenter cohort study was conducted in 20 public hospitals and a public center for COVID-19 screen-ing. During the first wave of the pandemic, from 6 April to 11 May 2020, all patients tested positive for COVID-19 confirmed by RT-PCR underwent two follow-up ENT consultations within 10 days of symptom onset. The main outcome measures were the evolution of medical management (out-patient care, standard hospital admission, and ICU admission) at diagnosis and along the clinical course of COVID-19 disease. Results: Among 481 patients included, the prevalence of OD was 60.7%, and it affected mostly female patients (74.3%) under 65 years old (92.5%), with fewer comor-bidities than patients with normal olfactory function. Here, 99.3% (290/292) of patients with OD presented with non-severe COVID-19 disease. Patients reporting OD were significantly less hospi-talized than the ones managed as outpatients, in either a standard medical unit or an ICU. Conclu-sions: As regards the clinical course of COVID-19 disease, OD could predict a decreased risk of hospitalization during the first wave of the pandemic. olfactory dysfunction anosmia phantosmia parosmia COVID-19 taste dysfunction Science Q Léo Delbos verfasserin aut Pierre-André Natella verfasserin aut Thomas Radulesco verfasserin aut Mihaela Alexandru verfasserin aut Emmanuel Bartaire verfasserin aut Sophie Bartier verfasserin aut Gonda Benoite verfasserin aut Emilie Bequignon verfasserin aut Laurent Castillo verfasserin aut Florence Canouï-Poitrine verfasserin aut Florent Carsuzaa verfasserin aut Alain Corré verfasserin aut André Coste verfasserin aut Vincent Couloigner verfasserin aut Clémentine Daveau verfasserin aut Paul De Boissieu verfasserin aut Guillaume De Bonnecaze verfasserin aut Ludovic De Gabory verfasserin aut Christian Debry verfasserin aut Simon Deraedt verfasserin aut Xavier Dufour verfasserin aut Wissame El Bakkouri verfasserin aut Laurent Gilain verfasserin aut Stéphane Hans verfasserin aut Charlotte Hautefort verfasserin aut Ruben Hermann verfasserin aut Roger Jankowski verfasserin aut Candice La Croix verfasserin aut Jean-Baptiste Lecanu verfasserin aut Olivier Malard verfasserin aut Justin Michel verfasserin aut Yann Nguyen verfasserin aut Jerome Nevoux verfasserin aut Jean-François Papon verfasserin aut Vincent Patron verfasserin aut Marine Prigent verfasserin aut Virginie Pruliere-Escabasse verfasserin aut Marion Renaud verfasserin aut Cécile Rumeau verfasserin aut Dominique Salmon verfasserin aut Nicolas Saroul verfasserin aut Elie Serrano verfasserin aut Christine Nhung Tran Khai verfasserin aut Stéphane Tringali verfasserin aut Eric Truy verfasserin aut Clair Vandersteen verfasserin aut Benjamin Verillaud verfasserin aut Raphaël Veil verfasserin aut Maxime Fieux verfasserin aut In Life MDPI AG, 2012 14(2024), 3, p 293 (DE-627)718627156 (DE-600)2662250-6 20751729 nnns volume:14 year:2024 number:3, p 293 https://doi.org/10.3390/life14030293 kostenfrei https://doaj.org/article/483e5d4d89164fbeb9f78d1f473bbd59 kostenfrei https://www.mdpi.com/2075-1729/14/3/293 kostenfrei https://doaj.org/toc/2075-1729 Journal toc kostenfrei GBV_USEFLAG_A SYSFLAG_A GBV_DOAJ GBV_ILN_20 GBV_ILN_22 GBV_ILN_23 GBV_ILN_24 GBV_ILN_31 GBV_ILN_39 GBV_ILN_40 GBV_ILN_62 GBV_ILN_63 GBV_ILN_65 GBV_ILN_69 GBV_ILN_70 GBV_ILN_73 GBV_ILN_74 GBV_ILN_95 GBV_ILN_105 GBV_ILN_110 GBV_ILN_151 GBV_ILN_161 GBV_ILN_170 GBV_ILN_206 GBV_ILN_213 GBV_ILN_230 GBV_ILN_285 GBV_ILN_293 GBV_ILN_602 GBV_ILN_2005 GBV_ILN_2009 GBV_ILN_2011 GBV_ILN_2014 GBV_ILN_2055 GBV_ILN_2111 GBV_ILN_4012 GBV_ILN_4037 GBV_ILN_4112 GBV_ILN_4125 GBV_ILN_4126 GBV_ILN_4249 GBV_ILN_4305 GBV_ILN_4306 GBV_ILN_4307 GBV_ILN_4313 GBV_ILN_4322 GBV_ILN_4323 GBV_ILN_4324 GBV_ILN_4325 GBV_ILN_4338 GBV_ILN_4367 GBV_ILN_4700 AR 14 2024 3, p 293 |
| spelling |
10.3390/life14030293 doi (DE-627)DOAJ100475892 (DE-599)DOAJ483e5d4d89164fbeb9f78d1f473bbd59 DE-627 ger DE-627 rakwb eng Anne-Laure Hamel verfasserin aut The Prognostic Value of Olfactory Dysfunction in Patients with COVID-19: The COVIDORA Study 2024 Text txt rdacontent Computermedien c rdamedia Online-Ressource cr rdacarrier Background: Among all studies describing COVID-19 clinical features during the first wave of the pandemic, only a few retrospective studies have assessed the correlation between olfac-tory dysfunction (OD) and the evolution of disease severity. The main aim was to assess whether OD is a predictive factor of COVID-19 severity based on the patient’s medical management (outpa-tient care, standard hospital admission, and ICU admission). Methods: A national, prospective, mul-ticenter cohort study was conducted in 20 public hospitals and a public center for COVID-19 screen-ing. During the first wave of the pandemic, from 6 April to 11 May 2020, all patients tested positive for COVID-19 confirmed by RT-PCR underwent two follow-up ENT consultations within 10 days of symptom onset. The main outcome measures were the evolution of medical management (out-patient care, standard hospital admission, and ICU admission) at diagnosis and along the clinical course of COVID-19 disease. Results: Among 481 patients included, the prevalence of OD was 60.7%, and it affected mostly female patients (74.3%) under 65 years old (92.5%), with fewer comor-bidities than patients with normal olfactory function. Here, 99.3% (290/292) of patients with OD presented with non-severe COVID-19 disease. Patients reporting OD were significantly less hospi-talized than the ones managed as outpatients, in either a standard medical unit or an ICU. Conclu-sions: As regards the clinical course of COVID-19 disease, OD could predict a decreased risk of hospitalization during the first wave of the pandemic. olfactory dysfunction anosmia phantosmia parosmia COVID-19 taste dysfunction Science Q Léo Delbos verfasserin aut Pierre-André Natella verfasserin aut Thomas Radulesco verfasserin aut Mihaela Alexandru verfasserin aut Emmanuel Bartaire verfasserin aut Sophie Bartier verfasserin aut Gonda Benoite verfasserin aut Emilie Bequignon verfasserin aut Laurent Castillo verfasserin aut Florence Canouï-Poitrine verfasserin aut Florent Carsuzaa verfasserin aut Alain Corré verfasserin aut André Coste verfasserin aut Vincent Couloigner verfasserin aut Clémentine Daveau verfasserin aut Paul De Boissieu verfasserin aut Guillaume De Bonnecaze verfasserin aut Ludovic De Gabory verfasserin aut Christian Debry verfasserin aut Simon Deraedt verfasserin aut Xavier Dufour verfasserin aut Wissame El Bakkouri verfasserin aut Laurent Gilain verfasserin aut Stéphane Hans verfasserin aut Charlotte Hautefort verfasserin aut Ruben Hermann verfasserin aut Roger Jankowski verfasserin aut Candice La Croix verfasserin aut Jean-Baptiste Lecanu verfasserin aut Olivier Malard verfasserin aut Justin Michel verfasserin aut Yann Nguyen verfasserin aut Jerome Nevoux verfasserin aut Jean-François Papon verfasserin aut Vincent Patron verfasserin aut Marine Prigent verfasserin aut Virginie Pruliere-Escabasse verfasserin aut Marion Renaud verfasserin aut Cécile Rumeau verfasserin aut Dominique Salmon verfasserin aut Nicolas Saroul verfasserin aut Elie Serrano verfasserin aut Christine Nhung Tran Khai verfasserin aut Stéphane Tringali verfasserin aut Eric Truy verfasserin aut Clair Vandersteen verfasserin aut Benjamin Verillaud verfasserin aut Raphaël Veil verfasserin aut Maxime Fieux verfasserin aut In Life MDPI AG, 2012 14(2024), 3, p 293 (DE-627)718627156 (DE-600)2662250-6 20751729 nnns volume:14 year:2024 number:3, p 293 https://doi.org/10.3390/life14030293 kostenfrei https://doaj.org/article/483e5d4d89164fbeb9f78d1f473bbd59 kostenfrei https://www.mdpi.com/2075-1729/14/3/293 kostenfrei https://doaj.org/toc/2075-1729 Journal toc kostenfrei GBV_USEFLAG_A SYSFLAG_A GBV_DOAJ GBV_ILN_20 GBV_ILN_22 GBV_ILN_23 GBV_ILN_24 GBV_ILN_31 GBV_ILN_39 GBV_ILN_40 GBV_ILN_62 GBV_ILN_63 GBV_ILN_65 GBV_ILN_69 GBV_ILN_70 GBV_ILN_73 GBV_ILN_74 GBV_ILN_95 GBV_ILN_105 GBV_ILN_110 GBV_ILN_151 GBV_ILN_161 GBV_ILN_170 GBV_ILN_206 GBV_ILN_213 GBV_ILN_230 GBV_ILN_285 GBV_ILN_293 GBV_ILN_602 GBV_ILN_2005 GBV_ILN_2009 GBV_ILN_2011 GBV_ILN_2014 GBV_ILN_2055 GBV_ILN_2111 GBV_ILN_4012 GBV_ILN_4037 GBV_ILN_4112 GBV_ILN_4125 GBV_ILN_4126 GBV_ILN_4249 GBV_ILN_4305 GBV_ILN_4306 GBV_ILN_4307 GBV_ILN_4313 GBV_ILN_4322 GBV_ILN_4323 GBV_ILN_4324 GBV_ILN_4325 GBV_ILN_4338 GBV_ILN_4367 GBV_ILN_4700 AR 14 2024 3, p 293 |
| allfields_unstemmed |
10.3390/life14030293 doi (DE-627)DOAJ100475892 (DE-599)DOAJ483e5d4d89164fbeb9f78d1f473bbd59 DE-627 ger DE-627 rakwb eng Anne-Laure Hamel verfasserin aut The Prognostic Value of Olfactory Dysfunction in Patients with COVID-19: The COVIDORA Study 2024 Text txt rdacontent Computermedien c rdamedia Online-Ressource cr rdacarrier Background: Among all studies describing COVID-19 clinical features during the first wave of the pandemic, only a few retrospective studies have assessed the correlation between olfac-tory dysfunction (OD) and the evolution of disease severity. The main aim was to assess whether OD is a predictive factor of COVID-19 severity based on the patient’s medical management (outpa-tient care, standard hospital admission, and ICU admission). Methods: A national, prospective, mul-ticenter cohort study was conducted in 20 public hospitals and a public center for COVID-19 screen-ing. During the first wave of the pandemic, from 6 April to 11 May 2020, all patients tested positive for COVID-19 confirmed by RT-PCR underwent two follow-up ENT consultations within 10 days of symptom onset. The main outcome measures were the evolution of medical management (out-patient care, standard hospital admission, and ICU admission) at diagnosis and along the clinical course of COVID-19 disease. Results: Among 481 patients included, the prevalence of OD was 60.7%, and it affected mostly female patients (74.3%) under 65 years old (92.5%), with fewer comor-bidities than patients with normal olfactory function. Here, 99.3% (290/292) of patients with OD presented with non-severe COVID-19 disease. Patients reporting OD were significantly less hospi-talized than the ones managed as outpatients, in either a standard medical unit or an ICU. Conclu-sions: As regards the clinical course of COVID-19 disease, OD could predict a decreased risk of hospitalization during the first wave of the pandemic. olfactory dysfunction anosmia phantosmia parosmia COVID-19 taste dysfunction Science Q Léo Delbos verfasserin aut Pierre-André Natella verfasserin aut Thomas Radulesco verfasserin aut Mihaela Alexandru verfasserin aut Emmanuel Bartaire verfasserin aut Sophie Bartier verfasserin aut Gonda Benoite verfasserin aut Emilie Bequignon verfasserin aut Laurent Castillo verfasserin aut Florence Canouï-Poitrine verfasserin aut Florent Carsuzaa verfasserin aut Alain Corré verfasserin aut André Coste verfasserin aut Vincent Couloigner verfasserin aut Clémentine Daveau verfasserin aut Paul De Boissieu verfasserin aut Guillaume De Bonnecaze verfasserin aut Ludovic De Gabory verfasserin aut Christian Debry verfasserin aut Simon Deraedt verfasserin aut Xavier Dufour verfasserin aut Wissame El Bakkouri verfasserin aut Laurent Gilain verfasserin aut Stéphane Hans verfasserin aut Charlotte Hautefort verfasserin aut Ruben Hermann verfasserin aut Roger Jankowski verfasserin aut Candice La Croix verfasserin aut Jean-Baptiste Lecanu verfasserin aut Olivier Malard verfasserin aut Justin Michel verfasserin aut Yann Nguyen verfasserin aut Jerome Nevoux verfasserin aut Jean-François Papon verfasserin aut Vincent Patron verfasserin aut Marine Prigent verfasserin aut Virginie Pruliere-Escabasse verfasserin aut Marion Renaud verfasserin aut Cécile Rumeau verfasserin aut Dominique Salmon verfasserin aut Nicolas Saroul verfasserin aut Elie Serrano verfasserin aut Christine Nhung Tran Khai verfasserin aut Stéphane Tringali verfasserin aut Eric Truy verfasserin aut Clair Vandersteen verfasserin aut Benjamin Verillaud verfasserin aut Raphaël Veil verfasserin aut Maxime Fieux verfasserin aut In Life MDPI AG, 2012 14(2024), 3, p 293 (DE-627)718627156 (DE-600)2662250-6 20751729 nnns volume:14 year:2024 number:3, p 293 https://doi.org/10.3390/life14030293 kostenfrei https://doaj.org/article/483e5d4d89164fbeb9f78d1f473bbd59 kostenfrei https://www.mdpi.com/2075-1729/14/3/293 kostenfrei https://doaj.org/toc/2075-1729 Journal toc kostenfrei GBV_USEFLAG_A SYSFLAG_A GBV_DOAJ GBV_ILN_20 GBV_ILN_22 GBV_ILN_23 GBV_ILN_24 GBV_ILN_31 GBV_ILN_39 GBV_ILN_40 GBV_ILN_62 GBV_ILN_63 GBV_ILN_65 GBV_ILN_69 GBV_ILN_70 GBV_ILN_73 GBV_ILN_74 GBV_ILN_95 GBV_ILN_105 GBV_ILN_110 GBV_ILN_151 GBV_ILN_161 GBV_ILN_170 GBV_ILN_206 GBV_ILN_213 GBV_ILN_230 GBV_ILN_285 GBV_ILN_293 GBV_ILN_602 GBV_ILN_2005 GBV_ILN_2009 GBV_ILN_2011 GBV_ILN_2014 GBV_ILN_2055 GBV_ILN_2111 GBV_ILN_4012 GBV_ILN_4037 GBV_ILN_4112 GBV_ILN_4125 GBV_ILN_4126 GBV_ILN_4249 GBV_ILN_4305 GBV_ILN_4306 GBV_ILN_4307 GBV_ILN_4313 GBV_ILN_4322 GBV_ILN_4323 GBV_ILN_4324 GBV_ILN_4325 GBV_ILN_4338 GBV_ILN_4367 GBV_ILN_4700 AR 14 2024 3, p 293 |
| allfieldsGer |
10.3390/life14030293 doi (DE-627)DOAJ100475892 (DE-599)DOAJ483e5d4d89164fbeb9f78d1f473bbd59 DE-627 ger DE-627 rakwb eng Anne-Laure Hamel verfasserin aut The Prognostic Value of Olfactory Dysfunction in Patients with COVID-19: The COVIDORA Study 2024 Text txt rdacontent Computermedien c rdamedia Online-Ressource cr rdacarrier Background: Among all studies describing COVID-19 clinical features during the first wave of the pandemic, only a few retrospective studies have assessed the correlation between olfac-tory dysfunction (OD) and the evolution of disease severity. The main aim was to assess whether OD is a predictive factor of COVID-19 severity based on the patient’s medical management (outpa-tient care, standard hospital admission, and ICU admission). Methods: A national, prospective, mul-ticenter cohort study was conducted in 20 public hospitals and a public center for COVID-19 screen-ing. During the first wave of the pandemic, from 6 April to 11 May 2020, all patients tested positive for COVID-19 confirmed by RT-PCR underwent two follow-up ENT consultations within 10 days of symptom onset. The main outcome measures were the evolution of medical management (out-patient care, standard hospital admission, and ICU admission) at diagnosis and along the clinical course of COVID-19 disease. Results: Among 481 patients included, the prevalence of OD was 60.7%, and it affected mostly female patients (74.3%) under 65 years old (92.5%), with fewer comor-bidities than patients with normal olfactory function. Here, 99.3% (290/292) of patients with OD presented with non-severe COVID-19 disease. Patients reporting OD were significantly less hospi-talized than the ones managed as outpatients, in either a standard medical unit or an ICU. Conclu-sions: As regards the clinical course of COVID-19 disease, OD could predict a decreased risk of hospitalization during the first wave of the pandemic. olfactory dysfunction anosmia phantosmia parosmia COVID-19 taste dysfunction Science Q Léo Delbos verfasserin aut Pierre-André Natella verfasserin aut Thomas Radulesco verfasserin aut Mihaela Alexandru verfasserin aut Emmanuel Bartaire verfasserin aut Sophie Bartier verfasserin aut Gonda Benoite verfasserin aut Emilie Bequignon verfasserin aut Laurent Castillo verfasserin aut Florence Canouï-Poitrine verfasserin aut Florent Carsuzaa verfasserin aut Alain Corré verfasserin aut André Coste verfasserin aut Vincent Couloigner verfasserin aut Clémentine Daveau verfasserin aut Paul De Boissieu verfasserin aut Guillaume De Bonnecaze verfasserin aut Ludovic De Gabory verfasserin aut Christian Debry verfasserin aut Simon Deraedt verfasserin aut Xavier Dufour verfasserin aut Wissame El Bakkouri verfasserin aut Laurent Gilain verfasserin aut Stéphane Hans verfasserin aut Charlotte Hautefort verfasserin aut Ruben Hermann verfasserin aut Roger Jankowski verfasserin aut Candice La Croix verfasserin aut Jean-Baptiste Lecanu verfasserin aut Olivier Malard verfasserin aut Justin Michel verfasserin aut Yann Nguyen verfasserin aut Jerome Nevoux verfasserin aut Jean-François Papon verfasserin aut Vincent Patron verfasserin aut Marine Prigent verfasserin aut Virginie Pruliere-Escabasse verfasserin aut Marion Renaud verfasserin aut Cécile Rumeau verfasserin aut Dominique Salmon verfasserin aut Nicolas Saroul verfasserin aut Elie Serrano verfasserin aut Christine Nhung Tran Khai verfasserin aut Stéphane Tringali verfasserin aut Eric Truy verfasserin aut Clair Vandersteen verfasserin aut Benjamin Verillaud verfasserin aut Raphaël Veil verfasserin aut Maxime Fieux verfasserin aut In Life MDPI AG, 2012 14(2024), 3, p 293 (DE-627)718627156 (DE-600)2662250-6 20751729 nnns volume:14 year:2024 number:3, p 293 https://doi.org/10.3390/life14030293 kostenfrei https://doaj.org/article/483e5d4d89164fbeb9f78d1f473bbd59 kostenfrei https://www.mdpi.com/2075-1729/14/3/293 kostenfrei https://doaj.org/toc/2075-1729 Journal toc kostenfrei GBV_USEFLAG_A SYSFLAG_A GBV_DOAJ GBV_ILN_20 GBV_ILN_22 GBV_ILN_23 GBV_ILN_24 GBV_ILN_31 GBV_ILN_39 GBV_ILN_40 GBV_ILN_62 GBV_ILN_63 GBV_ILN_65 GBV_ILN_69 GBV_ILN_70 GBV_ILN_73 GBV_ILN_74 GBV_ILN_95 GBV_ILN_105 GBV_ILN_110 GBV_ILN_151 GBV_ILN_161 GBV_ILN_170 GBV_ILN_206 GBV_ILN_213 GBV_ILN_230 GBV_ILN_285 GBV_ILN_293 GBV_ILN_602 GBV_ILN_2005 GBV_ILN_2009 GBV_ILN_2011 GBV_ILN_2014 GBV_ILN_2055 GBV_ILN_2111 GBV_ILN_4012 GBV_ILN_4037 GBV_ILN_4112 GBV_ILN_4125 GBV_ILN_4126 GBV_ILN_4249 GBV_ILN_4305 GBV_ILN_4306 GBV_ILN_4307 GBV_ILN_4313 GBV_ILN_4322 GBV_ILN_4323 GBV_ILN_4324 GBV_ILN_4325 GBV_ILN_4338 GBV_ILN_4367 GBV_ILN_4700 AR 14 2024 3, p 293 |
| allfieldsSound |
10.3390/life14030293 doi (DE-627)DOAJ100475892 (DE-599)DOAJ483e5d4d89164fbeb9f78d1f473bbd59 DE-627 ger DE-627 rakwb eng Anne-Laure Hamel verfasserin aut The Prognostic Value of Olfactory Dysfunction in Patients with COVID-19: The COVIDORA Study 2024 Text txt rdacontent Computermedien c rdamedia Online-Ressource cr rdacarrier Background: Among all studies describing COVID-19 clinical features during the first wave of the pandemic, only a few retrospective studies have assessed the correlation between olfac-tory dysfunction (OD) and the evolution of disease severity. The main aim was to assess whether OD is a predictive factor of COVID-19 severity based on the patient’s medical management (outpa-tient care, standard hospital admission, and ICU admission). Methods: A national, prospective, mul-ticenter cohort study was conducted in 20 public hospitals and a public center for COVID-19 screen-ing. During the first wave of the pandemic, from 6 April to 11 May 2020, all patients tested positive for COVID-19 confirmed by RT-PCR underwent two follow-up ENT consultations within 10 days of symptom onset. The main outcome measures were the evolution of medical management (out-patient care, standard hospital admission, and ICU admission) at diagnosis and along the clinical course of COVID-19 disease. Results: Among 481 patients included, the prevalence of OD was 60.7%, and it affected mostly female patients (74.3%) under 65 years old (92.5%), with fewer comor-bidities than patients with normal olfactory function. Here, 99.3% (290/292) of patients with OD presented with non-severe COVID-19 disease. Patients reporting OD were significantly less hospi-talized than the ones managed as outpatients, in either a standard medical unit or an ICU. Conclu-sions: As regards the clinical course of COVID-19 disease, OD could predict a decreased risk of hospitalization during the first wave of the pandemic. olfactory dysfunction anosmia phantosmia parosmia COVID-19 taste dysfunction Science Q Léo Delbos verfasserin aut Pierre-André Natella verfasserin aut Thomas Radulesco verfasserin aut Mihaela Alexandru verfasserin aut Emmanuel Bartaire verfasserin aut Sophie Bartier verfasserin aut Gonda Benoite verfasserin aut Emilie Bequignon verfasserin aut Laurent Castillo verfasserin aut Florence Canouï-Poitrine verfasserin aut Florent Carsuzaa verfasserin aut Alain Corré verfasserin aut André Coste verfasserin aut Vincent Couloigner verfasserin aut Clémentine Daveau verfasserin aut Paul De Boissieu verfasserin aut Guillaume De Bonnecaze verfasserin aut Ludovic De Gabory verfasserin aut Christian Debry verfasserin aut Simon Deraedt verfasserin aut Xavier Dufour verfasserin aut Wissame El Bakkouri verfasserin aut Laurent Gilain verfasserin aut Stéphane Hans verfasserin aut Charlotte Hautefort verfasserin aut Ruben Hermann verfasserin aut Roger Jankowski verfasserin aut Candice La Croix verfasserin aut Jean-Baptiste Lecanu verfasserin aut Olivier Malard verfasserin aut Justin Michel verfasserin aut Yann Nguyen verfasserin aut Jerome Nevoux verfasserin aut Jean-François Papon verfasserin aut Vincent Patron verfasserin aut Marine Prigent verfasserin aut Virginie Pruliere-Escabasse verfasserin aut Marion Renaud verfasserin aut Cécile Rumeau verfasserin aut Dominique Salmon verfasserin aut Nicolas Saroul verfasserin aut Elie Serrano verfasserin aut Christine Nhung Tran Khai verfasserin aut Stéphane Tringali verfasserin aut Eric Truy verfasserin aut Clair Vandersteen verfasserin aut Benjamin Verillaud verfasserin aut Raphaël Veil verfasserin aut Maxime Fieux verfasserin aut In Life MDPI AG, 2012 14(2024), 3, p 293 (DE-627)718627156 (DE-600)2662250-6 20751729 nnns volume:14 year:2024 number:3, p 293 https://doi.org/10.3390/life14030293 kostenfrei https://doaj.org/article/483e5d4d89164fbeb9f78d1f473bbd59 kostenfrei https://www.mdpi.com/2075-1729/14/3/293 kostenfrei https://doaj.org/toc/2075-1729 Journal toc kostenfrei GBV_USEFLAG_A SYSFLAG_A GBV_DOAJ GBV_ILN_20 GBV_ILN_22 GBV_ILN_23 GBV_ILN_24 GBV_ILN_31 GBV_ILN_39 GBV_ILN_40 GBV_ILN_62 GBV_ILN_63 GBV_ILN_65 GBV_ILN_69 GBV_ILN_70 GBV_ILN_73 GBV_ILN_74 GBV_ILN_95 GBV_ILN_105 GBV_ILN_110 GBV_ILN_151 GBV_ILN_161 GBV_ILN_170 GBV_ILN_206 GBV_ILN_213 GBV_ILN_230 GBV_ILN_285 GBV_ILN_293 GBV_ILN_602 GBV_ILN_2005 GBV_ILN_2009 GBV_ILN_2011 GBV_ILN_2014 GBV_ILN_2055 GBV_ILN_2111 GBV_ILN_4012 GBV_ILN_4037 GBV_ILN_4112 GBV_ILN_4125 GBV_ILN_4126 GBV_ILN_4249 GBV_ILN_4305 GBV_ILN_4306 GBV_ILN_4307 GBV_ILN_4313 GBV_ILN_4322 GBV_ILN_4323 GBV_ILN_4324 GBV_ILN_4325 GBV_ILN_4338 GBV_ILN_4367 GBV_ILN_4700 AR 14 2024 3, p 293 |
| language |
English |
| source |
In Life 14(2024), 3, p 293 volume:14 year:2024 number:3, p 293 |
| sourceStr |
In Life 14(2024), 3, p 293 volume:14 year:2024 number:3, p 293 |
| format_phy_str_mv |
Article |
| institution |
findex.gbv.de |
| topic_facet |
olfactory dysfunction anosmia phantosmia parosmia COVID-19 taste dysfunction Science Q |
| isfreeaccess_bool |
true |
| container_title |
Life |
| authorswithroles_txt_mv |
Anne-Laure Hamel @@aut@@ Léo Delbos @@aut@@ Pierre-André Natella @@aut@@ Thomas Radulesco @@aut@@ Mihaela Alexandru @@aut@@ Emmanuel Bartaire @@aut@@ Sophie Bartier @@aut@@ Gonda Benoite @@aut@@ Emilie Bequignon @@aut@@ Laurent Castillo @@aut@@ Florence Canouï-Poitrine @@aut@@ Florent Carsuzaa @@aut@@ Alain Corré @@aut@@ André Coste @@aut@@ Vincent Couloigner @@aut@@ Clémentine Daveau @@aut@@ Paul De Boissieu @@aut@@ Guillaume De Bonnecaze @@aut@@ Ludovic De Gabory @@aut@@ Christian Debry @@aut@@ Simon Deraedt @@aut@@ Xavier Dufour @@aut@@ Wissame El Bakkouri @@aut@@ Laurent Gilain @@aut@@ Stéphane Hans @@aut@@ Charlotte Hautefort @@aut@@ Ruben Hermann @@aut@@ Roger Jankowski @@aut@@ Candice La Croix @@aut@@ Jean-Baptiste Lecanu @@aut@@ Olivier Malard @@aut@@ Justin Michel @@aut@@ Yann Nguyen @@aut@@ Jerome Nevoux @@aut@@ Jean-François Papon @@aut@@ Vincent Patron @@aut@@ Marine Prigent @@aut@@ Virginie Pruliere-Escabasse @@aut@@ Marion Renaud @@aut@@ Cécile Rumeau @@aut@@ Dominique Salmon @@aut@@ Nicolas Saroul @@aut@@ Elie Serrano @@aut@@ Christine Nhung Tran Khai @@aut@@ Stéphane Tringali @@aut@@ Eric Truy @@aut@@ Clair Vandersteen @@aut@@ Benjamin Verillaud @@aut@@ Raphaël Veil @@aut@@ Maxime Fieux @@aut@@ |
| publishDateDaySort_date |
2024-01-01T00:00:00Z |
| hierarchy_top_id |
718627156 |
| id |
DOAJ100475892 |
| language_de |
englisch |
| fullrecord |
<?xml version="1.0" encoding="UTF-8"?><collection xmlns="http://www.loc.gov/MARC21/slim"><record><leader>01000naa a22002652 4500</leader><controlfield tag="001">DOAJ100475892</controlfield><controlfield tag="003">DE-627</controlfield><controlfield tag="005">20240414095808.0</controlfield><controlfield tag="007">cr uuu---uuuuu</controlfield><controlfield tag="008">240414s2024 xx |||||o 00| ||eng c</controlfield><datafield tag="024" ind1="7" ind2=" "><subfield code="a">10.3390/life14030293</subfield><subfield code="2">doi</subfield></datafield><datafield tag="035" ind1=" " ind2=" "><subfield code="a">(DE-627)DOAJ100475892</subfield></datafield><datafield tag="035" ind1=" " ind2=" "><subfield code="a">(DE-599)DOAJ483e5d4d89164fbeb9f78d1f473bbd59</subfield></datafield><datafield tag="040" ind1=" " ind2=" "><subfield code="a">DE-627</subfield><subfield code="b">ger</subfield><subfield code="c">DE-627</subfield><subfield code="e">rakwb</subfield></datafield><datafield tag="041" ind1=" " ind2=" "><subfield code="a">eng</subfield></datafield><datafield tag="100" ind1="0" ind2=" "><subfield code="a">Anne-Laure Hamel</subfield><subfield code="e">verfasserin</subfield><subfield code="4">aut</subfield></datafield><datafield tag="245" ind1="1" ind2="4"><subfield code="a">The Prognostic Value of Olfactory Dysfunction in Patients with COVID-19: The COVIDORA Study</subfield></datafield><datafield tag="264" ind1=" " ind2="1"><subfield code="c">2024</subfield></datafield><datafield tag="336" ind1=" " ind2=" "><subfield code="a">Text</subfield><subfield code="b">txt</subfield><subfield code="2">rdacontent</subfield></datafield><datafield tag="337" ind1=" " ind2=" "><subfield code="a">Computermedien</subfield><subfield code="b">c</subfield><subfield code="2">rdamedia</subfield></datafield><datafield tag="338" ind1=" " ind2=" "><subfield code="a">Online-Ressource</subfield><subfield code="b">cr</subfield><subfield code="2">rdacarrier</subfield></datafield><datafield tag="520" ind1=" " ind2=" "><subfield code="a">Background: Among all studies describing COVID-19 clinical features during the first wave of the pandemic, only a few retrospective studies have assessed the correlation between olfac-tory dysfunction (OD) and the evolution of disease severity. The main aim was to assess whether OD is a predictive factor of COVID-19 severity based on the patient’s medical management (outpa-tient care, standard hospital admission, and ICU admission). Methods: A national, prospective, mul-ticenter cohort study was conducted in 20 public hospitals and a public center for COVID-19 screen-ing. During the first wave of the pandemic, from 6 April to 11 May 2020, all patients tested positive for COVID-19 confirmed by RT-PCR underwent two follow-up ENT consultations within 10 days of symptom onset. The main outcome measures were the evolution of medical management (out-patient care, standard hospital admission, and ICU admission) at diagnosis and along the clinical course of COVID-19 disease. Results: Among 481 patients included, the prevalence of OD was 60.7%, and it affected mostly female patients (74.3%) under 65 years old (92.5%), with fewer comor-bidities than patients with normal olfactory function. Here, 99.3% (290/292) of patients with OD presented with non-severe COVID-19 disease. Patients reporting OD were significantly less hospi-talized than the ones managed as outpatients, in either a standard medical unit or an ICU. Conclu-sions: As regards the clinical course of COVID-19 disease, OD could predict a decreased risk of hospitalization during the first wave of the pandemic.</subfield></datafield><datafield tag="650" ind1=" " ind2="4"><subfield code="a">olfactory dysfunction</subfield></datafield><datafield tag="650" ind1=" " ind2="4"><subfield code="a">anosmia</subfield></datafield><datafield tag="650" ind1=" " ind2="4"><subfield code="a">phantosmia</subfield></datafield><datafield tag="650" ind1=" " ind2="4"><subfield code="a">parosmia</subfield></datafield><datafield tag="650" ind1=" " ind2="4"><subfield code="a">COVID-19</subfield></datafield><datafield tag="650" ind1=" " ind2="4"><subfield code="a">taste dysfunction</subfield></datafield><datafield tag="653" ind1=" " ind2="0"><subfield code="a">Science</subfield></datafield><datafield tag="653" ind1=" " ind2="0"><subfield code="a">Q</subfield></datafield><datafield tag="700" ind1="0" ind2=" "><subfield code="a">Léo Delbos</subfield><subfield code="e">verfasserin</subfield><subfield code="4">aut</subfield></datafield><datafield tag="700" ind1="0" ind2=" "><subfield code="a">Pierre-André Natella</subfield><subfield code="e">verfasserin</subfield><subfield code="4">aut</subfield></datafield><datafield tag="700" ind1="0" ind2=" "><subfield code="a">Thomas Radulesco</subfield><subfield code="e">verfasserin</subfield><subfield code="4">aut</subfield></datafield><datafield tag="700" ind1="0" ind2=" "><subfield code="a">Mihaela Alexandru</subfield><subfield code="e">verfasserin</subfield><subfield code="4">aut</subfield></datafield><datafield tag="700" ind1="0" ind2=" "><subfield code="a">Emmanuel Bartaire</subfield><subfield code="e">verfasserin</subfield><subfield code="4">aut</subfield></datafield><datafield tag="700" ind1="0" ind2=" "><subfield code="a">Sophie Bartier</subfield><subfield code="e">verfasserin</subfield><subfield code="4">aut</subfield></datafield><datafield tag="700" ind1="0" ind2=" "><subfield code="a">Gonda Benoite</subfield><subfield code="e">verfasserin</subfield><subfield code="4">aut</subfield></datafield><datafield tag="700" ind1="0" ind2=" "><subfield code="a">Emilie Bequignon</subfield><subfield code="e">verfasserin</subfield><subfield code="4">aut</subfield></datafield><datafield tag="700" ind1="0" ind2=" "><subfield code="a">Laurent Castillo</subfield><subfield code="e">verfasserin</subfield><subfield code="4">aut</subfield></datafield><datafield tag="700" ind1="0" ind2=" "><subfield code="a">Florence Canouï-Poitrine</subfield><subfield code="e">verfasserin</subfield><subfield code="4">aut</subfield></datafield><datafield tag="700" ind1="0" ind2=" "><subfield code="a">Florent Carsuzaa</subfield><subfield code="e">verfasserin</subfield><subfield code="4">aut</subfield></datafield><datafield tag="700" ind1="0" ind2=" "><subfield code="a">Alain Corré</subfield><subfield code="e">verfasserin</subfield><subfield code="4">aut</subfield></datafield><datafield tag="700" ind1="0" ind2=" "><subfield code="a">André Coste</subfield><subfield code="e">verfasserin</subfield><subfield code="4">aut</subfield></datafield><datafield tag="700" ind1="0" ind2=" "><subfield code="a">Vincent Couloigner</subfield><subfield code="e">verfasserin</subfield><subfield code="4">aut</subfield></datafield><datafield tag="700" ind1="0" ind2=" "><subfield code="a">Clémentine Daveau</subfield><subfield code="e">verfasserin</subfield><subfield code="4">aut</subfield></datafield><datafield tag="700" ind1="0" ind2=" "><subfield code="a">Paul De Boissieu</subfield><subfield code="e">verfasserin</subfield><subfield code="4">aut</subfield></datafield><datafield tag="700" ind1="0" ind2=" "><subfield code="a">Guillaume De Bonnecaze</subfield><subfield code="e">verfasserin</subfield><subfield code="4">aut</subfield></datafield><datafield tag="700" ind1="0" ind2=" "><subfield code="a">Ludovic De Gabory</subfield><subfield code="e">verfasserin</subfield><subfield code="4">aut</subfield></datafield><datafield tag="700" ind1="0" ind2=" "><subfield code="a">Christian Debry</subfield><subfield code="e">verfasserin</subfield><subfield code="4">aut</subfield></datafield><datafield tag="700" ind1="0" ind2=" "><subfield code="a">Simon Deraedt</subfield><subfield code="e">verfasserin</subfield><subfield code="4">aut</subfield></datafield><datafield tag="700" ind1="0" ind2=" "><subfield code="a">Xavier Dufour</subfield><subfield code="e">verfasserin</subfield><subfield code="4">aut</subfield></datafield><datafield tag="700" ind1="0" ind2=" "><subfield code="a">Wissame El Bakkouri</subfield><subfield code="e">verfasserin</subfield><subfield code="4">aut</subfield></datafield><datafield tag="700" ind1="0" ind2=" "><subfield code="a">Laurent Gilain</subfield><subfield code="e">verfasserin</subfield><subfield code="4">aut</subfield></datafield><datafield tag="700" ind1="0" ind2=" "><subfield code="a">Stéphane Hans</subfield><subfield code="e">verfasserin</subfield><subfield code="4">aut</subfield></datafield><datafield tag="700" ind1="0" ind2=" "><subfield code="a">Charlotte Hautefort</subfield><subfield code="e">verfasserin</subfield><subfield code="4">aut</subfield></datafield><datafield tag="700" ind1="0" ind2=" "><subfield code="a">Ruben Hermann</subfield><subfield code="e">verfasserin</subfield><subfield code="4">aut</subfield></datafield><datafield tag="700" ind1="0" ind2=" "><subfield code="a">Roger Jankowski</subfield><subfield code="e">verfasserin</subfield><subfield code="4">aut</subfield></datafield><datafield tag="700" ind1="0" ind2=" "><subfield code="a">Candice La Croix</subfield><subfield code="e">verfasserin</subfield><subfield code="4">aut</subfield></datafield><datafield tag="700" ind1="0" ind2=" "><subfield code="a">Jean-Baptiste Lecanu</subfield><subfield code="e">verfasserin</subfield><subfield code="4">aut</subfield></datafield><datafield tag="700" ind1="0" ind2=" "><subfield code="a">Olivier Malard</subfield><subfield code="e">verfasserin</subfield><subfield code="4">aut</subfield></datafield><datafield tag="700" ind1="0" ind2=" "><subfield code="a">Justin Michel</subfield><subfield code="e">verfasserin</subfield><subfield code="4">aut</subfield></datafield><datafield tag="700" ind1="0" ind2=" "><subfield code="a">Yann Nguyen</subfield><subfield code="e">verfasserin</subfield><subfield code="4">aut</subfield></datafield><datafield tag="700" ind1="0" ind2=" "><subfield code="a">Jerome Nevoux</subfield><subfield code="e">verfasserin</subfield><subfield code="4">aut</subfield></datafield><datafield tag="700" ind1="0" ind2=" "><subfield code="a">Jean-François Papon</subfield><subfield code="e">verfasserin</subfield><subfield code="4">aut</subfield></datafield><datafield tag="700" ind1="0" ind2=" "><subfield code="a">Vincent Patron</subfield><subfield code="e">verfasserin</subfield><subfield code="4">aut</subfield></datafield><datafield tag="700" ind1="0" ind2=" "><subfield code="a">Marine Prigent</subfield><subfield code="e">verfasserin</subfield><subfield code="4">aut</subfield></datafield><datafield tag="700" ind1="0" ind2=" "><subfield code="a">Virginie Pruliere-Escabasse</subfield><subfield code="e">verfasserin</subfield><subfield code="4">aut</subfield></datafield><datafield tag="700" ind1="0" ind2=" "><subfield code="a">Marion Renaud</subfield><subfield code="e">verfasserin</subfield><subfield code="4">aut</subfield></datafield><datafield tag="700" ind1="0" ind2=" "><subfield code="a">Cécile Rumeau</subfield><subfield code="e">verfasserin</subfield><subfield code="4">aut</subfield></datafield><datafield tag="700" ind1="0" ind2=" "><subfield code="a">Dominique Salmon</subfield><subfield code="e">verfasserin</subfield><subfield code="4">aut</subfield></datafield><datafield tag="700" ind1="0" ind2=" "><subfield code="a">Nicolas Saroul</subfield><subfield code="e">verfasserin</subfield><subfield code="4">aut</subfield></datafield><datafield tag="700" ind1="0" ind2=" "><subfield code="a">Elie Serrano</subfield><subfield code="e">verfasserin</subfield><subfield code="4">aut</subfield></datafield><datafield tag="700" ind1="0" ind2=" "><subfield code="a">Christine Nhung Tran Khai</subfield><subfield code="e">verfasserin</subfield><subfield code="4">aut</subfield></datafield><datafield tag="700" ind1="0" ind2=" "><subfield code="a">Stéphane Tringali</subfield><subfield code="e">verfasserin</subfield><subfield code="4">aut</subfield></datafield><datafield tag="700" ind1="0" ind2=" "><subfield code="a">Eric Truy</subfield><subfield code="e">verfasserin</subfield><subfield code="4">aut</subfield></datafield><datafield tag="700" ind1="0" ind2=" "><subfield code="a">Clair Vandersteen</subfield><subfield code="e">verfasserin</subfield><subfield code="4">aut</subfield></datafield><datafield tag="700" ind1="0" ind2=" "><subfield code="a">Benjamin Verillaud</subfield><subfield code="e">verfasserin</subfield><subfield code="4">aut</subfield></datafield><datafield tag="700" ind1="0" ind2=" "><subfield code="a">Raphaël Veil</subfield><subfield code="e">verfasserin</subfield><subfield code="4">aut</subfield></datafield><datafield tag="700" ind1="0" ind2=" "><subfield code="a">Maxime Fieux</subfield><subfield code="e">verfasserin</subfield><subfield code="4">aut</subfield></datafield><datafield tag="773" ind1="0" ind2="8"><subfield code="i">In</subfield><subfield code="t">Life</subfield><subfield code="d">MDPI AG, 2012</subfield><subfield code="g">14(2024), 3, p 293</subfield><subfield code="w">(DE-627)718627156</subfield><subfield code="w">(DE-600)2662250-6</subfield><subfield code="x">20751729</subfield><subfield code="7">nnns</subfield></datafield><datafield tag="773" ind1="1" ind2="8"><subfield code="g">volume:14</subfield><subfield code="g">year:2024</subfield><subfield code="g">number:3, p 293</subfield></datafield><datafield tag="856" ind1="4" ind2="0"><subfield code="u">https://doi.org/10.3390/life14030293</subfield><subfield code="z">kostenfrei</subfield></datafield><datafield tag="856" ind1="4" ind2="0"><subfield code="u">https://doaj.org/article/483e5d4d89164fbeb9f78d1f473bbd59</subfield><subfield code="z">kostenfrei</subfield></datafield><datafield tag="856" ind1="4" ind2="0"><subfield code="u">https://www.mdpi.com/2075-1729/14/3/293</subfield><subfield code="z">kostenfrei</subfield></datafield><datafield tag="856" ind1="4" ind2="2"><subfield code="u">https://doaj.org/toc/2075-1729</subfield><subfield code="y">Journal toc</subfield><subfield code="z">kostenfrei</subfield></datafield><datafield tag="912" ind1=" " ind2=" "><subfield code="a">GBV_USEFLAG_A</subfield></datafield><datafield tag="912" ind1=" " ind2=" "><subfield code="a">SYSFLAG_A</subfield></datafield><datafield tag="912" ind1=" " ind2=" "><subfield code="a">GBV_DOAJ</subfield></datafield><datafield tag="912" ind1=" " ind2=" "><subfield code="a">GBV_ILN_20</subfield></datafield><datafield tag="912" ind1=" " ind2=" "><subfield code="a">GBV_ILN_22</subfield></datafield><datafield tag="912" ind1=" " ind2=" "><subfield code="a">GBV_ILN_23</subfield></datafield><datafield tag="912" ind1=" " ind2=" "><subfield code="a">GBV_ILN_24</subfield></datafield><datafield tag="912" ind1=" " ind2=" "><subfield code="a">GBV_ILN_31</subfield></datafield><datafield tag="912" ind1=" " ind2=" "><subfield code="a">GBV_ILN_39</subfield></datafield><datafield tag="912" ind1=" " ind2=" "><subfield code="a">GBV_ILN_40</subfield></datafield><datafield tag="912" ind1=" " ind2=" "><subfield code="a">GBV_ILN_62</subfield></datafield><datafield tag="912" ind1=" " ind2=" "><subfield code="a">GBV_ILN_63</subfield></datafield><datafield tag="912" ind1=" " ind2=" "><subfield code="a">GBV_ILN_65</subfield></datafield><datafield tag="912" ind1=" " ind2=" "><subfield code="a">GBV_ILN_69</subfield></datafield><datafield tag="912" ind1=" " ind2=" "><subfield code="a">GBV_ILN_70</subfield></datafield><datafield tag="912" ind1=" " ind2=" "><subfield code="a">GBV_ILN_73</subfield></datafield><datafield tag="912" ind1=" " ind2=" "><subfield code="a">GBV_ILN_74</subfield></datafield><datafield tag="912" ind1=" " ind2=" "><subfield code="a">GBV_ILN_95</subfield></datafield><datafield tag="912" ind1=" " ind2=" "><subfield code="a">GBV_ILN_105</subfield></datafield><datafield tag="912" ind1=" " ind2=" "><subfield code="a">GBV_ILN_110</subfield></datafield><datafield tag="912" ind1=" " ind2=" "><subfield code="a">GBV_ILN_151</subfield></datafield><datafield tag="912" ind1=" " ind2=" "><subfield code="a">GBV_ILN_161</subfield></datafield><datafield tag="912" ind1=" " ind2=" "><subfield code="a">GBV_ILN_170</subfield></datafield><datafield tag="912" ind1=" " ind2=" "><subfield code="a">GBV_ILN_206</subfield></datafield><datafield tag="912" ind1=" " ind2=" "><subfield code="a">GBV_ILN_213</subfield></datafield><datafield tag="912" ind1=" " ind2=" "><subfield code="a">GBV_ILN_230</subfield></datafield><datafield tag="912" ind1=" " ind2=" "><subfield code="a">GBV_ILN_285</subfield></datafield><datafield tag="912" ind1=" " ind2=" "><subfield code="a">GBV_ILN_293</subfield></datafield><datafield tag="912" ind1=" " ind2=" "><subfield code="a">GBV_ILN_602</subfield></datafield><datafield tag="912" ind1=" " ind2=" "><subfield code="a">GBV_ILN_2005</subfield></datafield><datafield tag="912" ind1=" " ind2=" "><subfield code="a">GBV_ILN_2009</subfield></datafield><datafield tag="912" ind1=" " ind2=" "><subfield code="a">GBV_ILN_2011</subfield></datafield><datafield tag="912" ind1=" " ind2=" "><subfield code="a">GBV_ILN_2014</subfield></datafield><datafield tag="912" ind1=" " ind2=" "><subfield code="a">GBV_ILN_2055</subfield></datafield><datafield tag="912" ind1=" " ind2=" "><subfield code="a">GBV_ILN_2111</subfield></datafield><datafield tag="912" ind1=" " ind2=" "><subfield code="a">GBV_ILN_4012</subfield></datafield><datafield tag="912" ind1=" " ind2=" "><subfield code="a">GBV_ILN_4037</subfield></datafield><datafield tag="912" ind1=" " ind2=" "><subfield code="a">GBV_ILN_4112</subfield></datafield><datafield tag="912" ind1=" " ind2=" "><subfield code="a">GBV_ILN_4125</subfield></datafield><datafield tag="912" ind1=" " ind2=" "><subfield code="a">GBV_ILN_4126</subfield></datafield><datafield tag="912" ind1=" " ind2=" "><subfield code="a">GBV_ILN_4249</subfield></datafield><datafield tag="912" ind1=" " ind2=" "><subfield code="a">GBV_ILN_4305</subfield></datafield><datafield tag="912" ind1=" " ind2=" "><subfield code="a">GBV_ILN_4306</subfield></datafield><datafield tag="912" ind1=" " ind2=" "><subfield code="a">GBV_ILN_4307</subfield></datafield><datafield tag="912" ind1=" " ind2=" "><subfield code="a">GBV_ILN_4313</subfield></datafield><datafield tag="912" ind1=" " ind2=" "><subfield code="a">GBV_ILN_4322</subfield></datafield><datafield tag="912" ind1=" " ind2=" "><subfield code="a">GBV_ILN_4323</subfield></datafield><datafield tag="912" ind1=" " ind2=" "><subfield code="a">GBV_ILN_4324</subfield></datafield><datafield tag="912" ind1=" " ind2=" "><subfield code="a">GBV_ILN_4325</subfield></datafield><datafield tag="912" ind1=" " ind2=" "><subfield code="a">GBV_ILN_4338</subfield></datafield><datafield tag="912" ind1=" " ind2=" "><subfield code="a">GBV_ILN_4367</subfield></datafield><datafield tag="912" ind1=" " ind2=" "><subfield code="a">GBV_ILN_4700</subfield></datafield><datafield tag="951" ind1=" " ind2=" "><subfield code="a">AR</subfield></datafield><datafield tag="952" ind1=" " ind2=" "><subfield code="d">14</subfield><subfield code="j">2024</subfield><subfield code="e">3, p 293</subfield></datafield></record></collection>
|
| author |
Anne-Laure Hamel |
| spellingShingle |
Anne-Laure Hamel misc olfactory dysfunction misc anosmia misc phantosmia misc parosmia misc COVID-19 misc taste dysfunction misc Science misc Q The Prognostic Value of Olfactory Dysfunction in Patients with COVID-19: The COVIDORA Study |
| authorStr |
Anne-Laure Hamel |
| ppnlink_with_tag_str_mv |
@@773@@(DE-627)718627156 |
| format |
electronic Article |
| delete_txt_mv |
keep |
| author_role |
aut aut aut aut aut aut aut aut aut aut aut aut aut aut aut aut aut aut aut aut aut aut aut aut aut aut aut aut aut aut aut aut aut aut aut aut aut aut aut aut aut aut aut aut aut aut aut aut aut aut |
| collection |
DOAJ |
| remote_str |
true |
| illustrated |
Not Illustrated |
| issn |
20751729 |
| topic_title |
The Prognostic Value of Olfactory Dysfunction in Patients with COVID-19: The COVIDORA Study olfactory dysfunction anosmia phantosmia parosmia COVID-19 taste dysfunction |
| topic |
misc olfactory dysfunction misc anosmia misc phantosmia misc parosmia misc COVID-19 misc taste dysfunction misc Science misc Q |
| topic_unstemmed |
misc olfactory dysfunction misc anosmia misc phantosmia misc parosmia misc COVID-19 misc taste dysfunction misc Science misc Q |
| topic_browse |
misc olfactory dysfunction misc anosmia misc phantosmia misc parosmia misc COVID-19 misc taste dysfunction misc Science misc Q |
| format_facet |
Elektronische Aufsätze Aufsätze Elektronische Ressource |
| format_main_str_mv |
Text Zeitschrift/Artikel |
| carriertype_str_mv |
cr |
| hierarchy_parent_title |
Life |
| hierarchy_parent_id |
718627156 |
| hierarchy_top_title |
Life |
| isfreeaccess_txt |
true |
| familylinks_str_mv |
(DE-627)718627156 (DE-600)2662250-6 |
| title |
The Prognostic Value of Olfactory Dysfunction in Patients with COVID-19: The COVIDORA Study |
| ctrlnum |
(DE-627)DOAJ100475892 (DE-599)DOAJ483e5d4d89164fbeb9f78d1f473bbd59 |
| title_full |
The Prognostic Value of Olfactory Dysfunction in Patients with COVID-19: The COVIDORA Study |
| author_sort |
Anne-Laure Hamel |
| journal |
Life |
| journalStr |
Life |
| lang_code |
eng |
| isOA_bool |
true |
| recordtype |
marc |
| publishDateSort |
2024 |
| contenttype_str_mv |
txt |
| author_browse |
Anne-Laure Hamel Léo Delbos Pierre-André Natella Thomas Radulesco Mihaela Alexandru Emmanuel Bartaire Sophie Bartier Gonda Benoite Emilie Bequignon Laurent Castillo Florence Canouï-Poitrine Florent Carsuzaa Alain Corré André Coste Vincent Couloigner Clémentine Daveau Paul De Boissieu Guillaume De Bonnecaze Ludovic De Gabory Christian Debry Simon Deraedt Xavier Dufour Wissame El Bakkouri Laurent Gilain Stéphane Hans Charlotte Hautefort Ruben Hermann Roger Jankowski Candice La Croix Jean-Baptiste Lecanu Olivier Malard Justin Michel Yann Nguyen Jerome Nevoux Jean-François Papon Vincent Patron Marine Prigent Virginie Pruliere-Escabasse Marion Renaud Cécile Rumeau Dominique Salmon Nicolas Saroul Elie Serrano Christine Nhung Tran Khai Stéphane Tringali Eric Truy Clair Vandersteen Benjamin Verillaud Raphaël Veil Maxime Fieux |
| container_volume |
14 |
| format_se |
Elektronische Aufsätze |
| author-letter |
Anne-Laure Hamel |
| doi_str_mv |
10.3390/life14030293 |
| author2-role |
verfasserin |
| title_sort |
prognostic value of olfactory dysfunction in patients with covid-19: the covidora study |
| title_auth |
The Prognostic Value of Olfactory Dysfunction in Patients with COVID-19: The COVIDORA Study |
| abstract |
Background: Among all studies describing COVID-19 clinical features during the first wave of the pandemic, only a few retrospective studies have assessed the correlation between olfac-tory dysfunction (OD) and the evolution of disease severity. The main aim was to assess whether OD is a predictive factor of COVID-19 severity based on the patient’s medical management (outpa-tient care, standard hospital admission, and ICU admission). Methods: A national, prospective, mul-ticenter cohort study was conducted in 20 public hospitals and a public center for COVID-19 screen-ing. During the first wave of the pandemic, from 6 April to 11 May 2020, all patients tested positive for COVID-19 confirmed by RT-PCR underwent two follow-up ENT consultations within 10 days of symptom onset. The main outcome measures were the evolution of medical management (out-patient care, standard hospital admission, and ICU admission) at diagnosis and along the clinical course of COVID-19 disease. Results: Among 481 patients included, the prevalence of OD was 60.7%, and it affected mostly female patients (74.3%) under 65 years old (92.5%), with fewer comor-bidities than patients with normal olfactory function. Here, 99.3% (290/292) of patients with OD presented with non-severe COVID-19 disease. Patients reporting OD were significantly less hospi-talized than the ones managed as outpatients, in either a standard medical unit or an ICU. Conclu-sions: As regards the clinical course of COVID-19 disease, OD could predict a decreased risk of hospitalization during the first wave of the pandemic. |
| abstractGer |
Background: Among all studies describing COVID-19 clinical features during the first wave of the pandemic, only a few retrospective studies have assessed the correlation between olfac-tory dysfunction (OD) and the evolution of disease severity. The main aim was to assess whether OD is a predictive factor of COVID-19 severity based on the patient’s medical management (outpa-tient care, standard hospital admission, and ICU admission). Methods: A national, prospective, mul-ticenter cohort study was conducted in 20 public hospitals and a public center for COVID-19 screen-ing. During the first wave of the pandemic, from 6 April to 11 May 2020, all patients tested positive for COVID-19 confirmed by RT-PCR underwent two follow-up ENT consultations within 10 days of symptom onset. The main outcome measures were the evolution of medical management (out-patient care, standard hospital admission, and ICU admission) at diagnosis and along the clinical course of COVID-19 disease. Results: Among 481 patients included, the prevalence of OD was 60.7%, and it affected mostly female patients (74.3%) under 65 years old (92.5%), with fewer comor-bidities than patients with normal olfactory function. Here, 99.3% (290/292) of patients with OD presented with non-severe COVID-19 disease. Patients reporting OD were significantly less hospi-talized than the ones managed as outpatients, in either a standard medical unit or an ICU. Conclu-sions: As regards the clinical course of COVID-19 disease, OD could predict a decreased risk of hospitalization during the first wave of the pandemic. |
| abstract_unstemmed |
Background: Among all studies describing COVID-19 clinical features during the first wave of the pandemic, only a few retrospective studies have assessed the correlation between olfac-tory dysfunction (OD) and the evolution of disease severity. The main aim was to assess whether OD is a predictive factor of COVID-19 severity based on the patient’s medical management (outpa-tient care, standard hospital admission, and ICU admission). Methods: A national, prospective, mul-ticenter cohort study was conducted in 20 public hospitals and a public center for COVID-19 screen-ing. During the first wave of the pandemic, from 6 April to 11 May 2020, all patients tested positive for COVID-19 confirmed by RT-PCR underwent two follow-up ENT consultations within 10 days of symptom onset. The main outcome measures were the evolution of medical management (out-patient care, standard hospital admission, and ICU admission) at diagnosis and along the clinical course of COVID-19 disease. Results: Among 481 patients included, the prevalence of OD was 60.7%, and it affected mostly female patients (74.3%) under 65 years old (92.5%), with fewer comor-bidities than patients with normal olfactory function. Here, 99.3% (290/292) of patients with OD presented with non-severe COVID-19 disease. Patients reporting OD were significantly less hospi-talized than the ones managed as outpatients, in either a standard medical unit or an ICU. Conclu-sions: As regards the clinical course of COVID-19 disease, OD could predict a decreased risk of hospitalization during the first wave of the pandemic. |
| collection_details |
GBV_USEFLAG_A SYSFLAG_A GBV_DOAJ GBV_ILN_20 GBV_ILN_22 GBV_ILN_23 GBV_ILN_24 GBV_ILN_31 GBV_ILN_39 GBV_ILN_40 GBV_ILN_62 GBV_ILN_63 GBV_ILN_65 GBV_ILN_69 GBV_ILN_70 GBV_ILN_73 GBV_ILN_74 GBV_ILN_95 GBV_ILN_105 GBV_ILN_110 GBV_ILN_151 GBV_ILN_161 GBV_ILN_170 GBV_ILN_206 GBV_ILN_213 GBV_ILN_230 GBV_ILN_285 GBV_ILN_293 GBV_ILN_602 GBV_ILN_2005 GBV_ILN_2009 GBV_ILN_2011 GBV_ILN_2014 GBV_ILN_2055 GBV_ILN_2111 GBV_ILN_4012 GBV_ILN_4037 GBV_ILN_4112 GBV_ILN_4125 GBV_ILN_4126 GBV_ILN_4249 GBV_ILN_4305 GBV_ILN_4306 GBV_ILN_4307 GBV_ILN_4313 GBV_ILN_4322 GBV_ILN_4323 GBV_ILN_4324 GBV_ILN_4325 GBV_ILN_4338 GBV_ILN_4367 GBV_ILN_4700 |
| container_issue |
3, p 293 |
| title_short |
The Prognostic Value of Olfactory Dysfunction in Patients with COVID-19: The COVIDORA Study |
| url |
https://doi.org/10.3390/life14030293 https://doaj.org/article/483e5d4d89164fbeb9f78d1f473bbd59 https://www.mdpi.com/2075-1729/14/3/293 https://doaj.org/toc/2075-1729 |
| remote_bool |
true |
| author2 |
Léo Delbos Pierre-André Natella Thomas Radulesco Mihaela Alexandru Emmanuel Bartaire Sophie Bartier Gonda Benoite Emilie Bequignon Laurent Castillo Florence Canouï-Poitrine Florent Carsuzaa Alain Corré André Coste Vincent Couloigner Clémentine Daveau Paul De Boissieu Guillaume De Bonnecaze Ludovic De Gabory Christian Debry Simon Deraedt Xavier Dufour Wissame El Bakkouri Laurent Gilain Stéphane Hans Charlotte Hautefort Ruben Hermann Roger Jankowski Candice La Croix Jean-Baptiste Lecanu Olivier Malard Justin Michel Yann Nguyen Jerome Nevoux Jean-François Papon Vincent Patron Marine Prigent Virginie Pruliere-Escabasse Marion Renaud Cécile Rumeau Dominique Salmon Nicolas Saroul Elie Serrano Christine Nhung Tran Khai Stéphane Tringali Eric Truy Clair Vandersteen Benjamin Verillaud Raphaël Veil Maxime Fieux |
| author2Str |
Léo Delbos Pierre-André Natella Thomas Radulesco Mihaela Alexandru Emmanuel Bartaire Sophie Bartier Gonda Benoite Emilie Bequignon Laurent Castillo Florence Canouï-Poitrine Florent Carsuzaa Alain Corré André Coste Vincent Couloigner Clémentine Daveau Paul De Boissieu Guillaume De Bonnecaze Ludovic De Gabory Christian Debry Simon Deraedt Xavier Dufour Wissame El Bakkouri Laurent Gilain Stéphane Hans Charlotte Hautefort Ruben Hermann Roger Jankowski Candice La Croix Jean-Baptiste Lecanu Olivier Malard Justin Michel Yann Nguyen Jerome Nevoux Jean-François Papon Vincent Patron Marine Prigent Virginie Pruliere-Escabasse Marion Renaud Cécile Rumeau Dominique Salmon Nicolas Saroul Elie Serrano Christine Nhung Tran Khai Stéphane Tringali Eric Truy Clair Vandersteen Benjamin Verillaud Raphaël Veil Maxime Fieux |
| ppnlink |
718627156 |
| mediatype_str_mv |
c |
| isOA_txt |
true |
| hochschulschrift_bool |
false |
| doi_str |
10.3390/life14030293 |
| up_date |
2024-07-03T14:53:44.386Z |
| _version_ |
1803570039370022912 |
| fullrecord_marcxml |
<?xml version="1.0" encoding="UTF-8"?><collection xmlns="http://www.loc.gov/MARC21/slim"><record><leader>01000naa a22002652 4500</leader><controlfield tag="001">DOAJ100475892</controlfield><controlfield tag="003">DE-627</controlfield><controlfield tag="005">20240414095808.0</controlfield><controlfield tag="007">cr uuu---uuuuu</controlfield><controlfield tag="008">240414s2024 xx |||||o 00| ||eng c</controlfield><datafield tag="024" ind1="7" ind2=" "><subfield code="a">10.3390/life14030293</subfield><subfield code="2">doi</subfield></datafield><datafield tag="035" ind1=" " ind2=" "><subfield code="a">(DE-627)DOAJ100475892</subfield></datafield><datafield tag="035" ind1=" " ind2=" "><subfield code="a">(DE-599)DOAJ483e5d4d89164fbeb9f78d1f473bbd59</subfield></datafield><datafield tag="040" ind1=" " ind2=" "><subfield code="a">DE-627</subfield><subfield code="b">ger</subfield><subfield code="c">DE-627</subfield><subfield code="e">rakwb</subfield></datafield><datafield tag="041" ind1=" " ind2=" "><subfield code="a">eng</subfield></datafield><datafield tag="100" ind1="0" ind2=" "><subfield code="a">Anne-Laure Hamel</subfield><subfield code="e">verfasserin</subfield><subfield code="4">aut</subfield></datafield><datafield tag="245" ind1="1" ind2="4"><subfield code="a">The Prognostic Value of Olfactory Dysfunction in Patients with COVID-19: The COVIDORA Study</subfield></datafield><datafield tag="264" ind1=" " ind2="1"><subfield code="c">2024</subfield></datafield><datafield tag="336" ind1=" " ind2=" "><subfield code="a">Text</subfield><subfield code="b">txt</subfield><subfield code="2">rdacontent</subfield></datafield><datafield tag="337" ind1=" " ind2=" "><subfield code="a">Computermedien</subfield><subfield code="b">c</subfield><subfield code="2">rdamedia</subfield></datafield><datafield tag="338" ind1=" " ind2=" "><subfield code="a">Online-Ressource</subfield><subfield code="b">cr</subfield><subfield code="2">rdacarrier</subfield></datafield><datafield tag="520" ind1=" " ind2=" "><subfield code="a">Background: Among all studies describing COVID-19 clinical features during the first wave of the pandemic, only a few retrospective studies have assessed the correlation between olfac-tory dysfunction (OD) and the evolution of disease severity. The main aim was to assess whether OD is a predictive factor of COVID-19 severity based on the patient’s medical management (outpa-tient care, standard hospital admission, and ICU admission). Methods: A national, prospective, mul-ticenter cohort study was conducted in 20 public hospitals and a public center for COVID-19 screen-ing. During the first wave of the pandemic, from 6 April to 11 May 2020, all patients tested positive for COVID-19 confirmed by RT-PCR underwent two follow-up ENT consultations within 10 days of symptom onset. The main outcome measures were the evolution of medical management (out-patient care, standard hospital admission, and ICU admission) at diagnosis and along the clinical course of COVID-19 disease. Results: Among 481 patients included, the prevalence of OD was 60.7%, and it affected mostly female patients (74.3%) under 65 years old (92.5%), with fewer comor-bidities than patients with normal olfactory function. Here, 99.3% (290/292) of patients with OD presented with non-severe COVID-19 disease. Patients reporting OD were significantly less hospi-talized than the ones managed as outpatients, in either a standard medical unit or an ICU. Conclu-sions: As regards the clinical course of COVID-19 disease, OD could predict a decreased risk of hospitalization during the first wave of the pandemic.</subfield></datafield><datafield tag="650" ind1=" " ind2="4"><subfield code="a">olfactory dysfunction</subfield></datafield><datafield tag="650" ind1=" " ind2="4"><subfield code="a">anosmia</subfield></datafield><datafield tag="650" ind1=" " ind2="4"><subfield code="a">phantosmia</subfield></datafield><datafield tag="650" ind1=" " ind2="4"><subfield code="a">parosmia</subfield></datafield><datafield tag="650" ind1=" " ind2="4"><subfield code="a">COVID-19</subfield></datafield><datafield tag="650" ind1=" " ind2="4"><subfield code="a">taste dysfunction</subfield></datafield><datafield tag="653" ind1=" " ind2="0"><subfield code="a">Science</subfield></datafield><datafield tag="653" ind1=" " ind2="0"><subfield code="a">Q</subfield></datafield><datafield tag="700" ind1="0" ind2=" "><subfield code="a">Léo Delbos</subfield><subfield code="e">verfasserin</subfield><subfield code="4">aut</subfield></datafield><datafield tag="700" ind1="0" ind2=" "><subfield code="a">Pierre-André Natella</subfield><subfield code="e">verfasserin</subfield><subfield code="4">aut</subfield></datafield><datafield tag="700" ind1="0" ind2=" "><subfield code="a">Thomas Radulesco</subfield><subfield code="e">verfasserin</subfield><subfield code="4">aut</subfield></datafield><datafield tag="700" ind1="0" ind2=" "><subfield code="a">Mihaela Alexandru</subfield><subfield code="e">verfasserin</subfield><subfield code="4">aut</subfield></datafield><datafield tag="700" ind1="0" ind2=" "><subfield code="a">Emmanuel Bartaire</subfield><subfield code="e">verfasserin</subfield><subfield code="4">aut</subfield></datafield><datafield tag="700" ind1="0" ind2=" "><subfield code="a">Sophie Bartier</subfield><subfield code="e">verfasserin</subfield><subfield code="4">aut</subfield></datafield><datafield tag="700" ind1="0" ind2=" "><subfield code="a">Gonda Benoite</subfield><subfield code="e">verfasserin</subfield><subfield code="4">aut</subfield></datafield><datafield tag="700" ind1="0" ind2=" "><subfield code="a">Emilie Bequignon</subfield><subfield code="e">verfasserin</subfield><subfield code="4">aut</subfield></datafield><datafield tag="700" ind1="0" ind2=" "><subfield code="a">Laurent Castillo</subfield><subfield code="e">verfasserin</subfield><subfield code="4">aut</subfield></datafield><datafield tag="700" ind1="0" ind2=" "><subfield code="a">Florence Canouï-Poitrine</subfield><subfield code="e">verfasserin</subfield><subfield code="4">aut</subfield></datafield><datafield tag="700" ind1="0" ind2=" "><subfield code="a">Florent Carsuzaa</subfield><subfield code="e">verfasserin</subfield><subfield code="4">aut</subfield></datafield><datafield tag="700" ind1="0" ind2=" "><subfield code="a">Alain Corré</subfield><subfield code="e">verfasserin</subfield><subfield code="4">aut</subfield></datafield><datafield tag="700" ind1="0" ind2=" "><subfield code="a">André Coste</subfield><subfield code="e">verfasserin</subfield><subfield code="4">aut</subfield></datafield><datafield tag="700" ind1="0" ind2=" "><subfield code="a">Vincent Couloigner</subfield><subfield code="e">verfasserin</subfield><subfield code="4">aut</subfield></datafield><datafield tag="700" ind1="0" ind2=" "><subfield code="a">Clémentine Daveau</subfield><subfield code="e">verfasserin</subfield><subfield code="4">aut</subfield></datafield><datafield tag="700" ind1="0" ind2=" "><subfield code="a">Paul De Boissieu</subfield><subfield code="e">verfasserin</subfield><subfield code="4">aut</subfield></datafield><datafield tag="700" ind1="0" ind2=" "><subfield code="a">Guillaume De Bonnecaze</subfield><subfield code="e">verfasserin</subfield><subfield code="4">aut</subfield></datafield><datafield tag="700" ind1="0" ind2=" "><subfield code="a">Ludovic De Gabory</subfield><subfield code="e">verfasserin</subfield><subfield code="4">aut</subfield></datafield><datafield tag="700" ind1="0" ind2=" "><subfield code="a">Christian Debry</subfield><subfield code="e">verfasserin</subfield><subfield code="4">aut</subfield></datafield><datafield tag="700" ind1="0" ind2=" "><subfield code="a">Simon Deraedt</subfield><subfield code="e">verfasserin</subfield><subfield code="4">aut</subfield></datafield><datafield tag="700" ind1="0" ind2=" "><subfield code="a">Xavier Dufour</subfield><subfield code="e">verfasserin</subfield><subfield code="4">aut</subfield></datafield><datafield tag="700" ind1="0" ind2=" "><subfield code="a">Wissame El Bakkouri</subfield><subfield code="e">verfasserin</subfield><subfield code="4">aut</subfield></datafield><datafield tag="700" ind1="0" ind2=" "><subfield code="a">Laurent Gilain</subfield><subfield code="e">verfasserin</subfield><subfield code="4">aut</subfield></datafield><datafield tag="700" ind1="0" ind2=" "><subfield code="a">Stéphane Hans</subfield><subfield code="e">verfasserin</subfield><subfield code="4">aut</subfield></datafield><datafield tag="700" ind1="0" ind2=" "><subfield code="a">Charlotte Hautefort</subfield><subfield code="e">verfasserin</subfield><subfield code="4">aut</subfield></datafield><datafield tag="700" ind1="0" ind2=" "><subfield code="a">Ruben Hermann</subfield><subfield code="e">verfasserin</subfield><subfield code="4">aut</subfield></datafield><datafield tag="700" ind1="0" ind2=" "><subfield code="a">Roger Jankowski</subfield><subfield code="e">verfasserin</subfield><subfield code="4">aut</subfield></datafield><datafield tag="700" ind1="0" ind2=" "><subfield code="a">Candice La Croix</subfield><subfield code="e">verfasserin</subfield><subfield code="4">aut</subfield></datafield><datafield tag="700" ind1="0" ind2=" "><subfield code="a">Jean-Baptiste Lecanu</subfield><subfield code="e">verfasserin</subfield><subfield code="4">aut</subfield></datafield><datafield tag="700" ind1="0" ind2=" "><subfield code="a">Olivier Malard</subfield><subfield code="e">verfasserin</subfield><subfield code="4">aut</subfield></datafield><datafield tag="700" ind1="0" ind2=" "><subfield code="a">Justin Michel</subfield><subfield code="e">verfasserin</subfield><subfield code="4">aut</subfield></datafield><datafield tag="700" ind1="0" ind2=" "><subfield code="a">Yann Nguyen</subfield><subfield code="e">verfasserin</subfield><subfield code="4">aut</subfield></datafield><datafield tag="700" ind1="0" ind2=" "><subfield code="a">Jerome Nevoux</subfield><subfield code="e">verfasserin</subfield><subfield code="4">aut</subfield></datafield><datafield tag="700" ind1="0" ind2=" "><subfield code="a">Jean-François Papon</subfield><subfield code="e">verfasserin</subfield><subfield code="4">aut</subfield></datafield><datafield tag="700" ind1="0" ind2=" "><subfield code="a">Vincent Patron</subfield><subfield code="e">verfasserin</subfield><subfield code="4">aut</subfield></datafield><datafield tag="700" ind1="0" ind2=" "><subfield code="a">Marine Prigent</subfield><subfield code="e">verfasserin</subfield><subfield code="4">aut</subfield></datafield><datafield tag="700" ind1="0" ind2=" "><subfield code="a">Virginie Pruliere-Escabasse</subfield><subfield code="e">verfasserin</subfield><subfield code="4">aut</subfield></datafield><datafield tag="700" ind1="0" ind2=" "><subfield code="a">Marion Renaud</subfield><subfield code="e">verfasserin</subfield><subfield code="4">aut</subfield></datafield><datafield tag="700" ind1="0" ind2=" "><subfield code="a">Cécile Rumeau</subfield><subfield code="e">verfasserin</subfield><subfield code="4">aut</subfield></datafield><datafield tag="700" ind1="0" ind2=" "><subfield code="a">Dominique Salmon</subfield><subfield code="e">verfasserin</subfield><subfield code="4">aut</subfield></datafield><datafield tag="700" ind1="0" ind2=" "><subfield code="a">Nicolas Saroul</subfield><subfield code="e">verfasserin</subfield><subfield code="4">aut</subfield></datafield><datafield tag="700" ind1="0" ind2=" "><subfield code="a">Elie Serrano</subfield><subfield code="e">verfasserin</subfield><subfield code="4">aut</subfield></datafield><datafield tag="700" ind1="0" ind2=" "><subfield code="a">Christine Nhung Tran Khai</subfield><subfield code="e">verfasserin</subfield><subfield code="4">aut</subfield></datafield><datafield tag="700" ind1="0" ind2=" "><subfield code="a">Stéphane Tringali</subfield><subfield code="e">verfasserin</subfield><subfield code="4">aut</subfield></datafield><datafield tag="700" ind1="0" ind2=" "><subfield code="a">Eric Truy</subfield><subfield code="e">verfasserin</subfield><subfield code="4">aut</subfield></datafield><datafield tag="700" ind1="0" ind2=" "><subfield code="a">Clair Vandersteen</subfield><subfield code="e">verfasserin</subfield><subfield code="4">aut</subfield></datafield><datafield tag="700" ind1="0" ind2=" "><subfield code="a">Benjamin Verillaud</subfield><subfield code="e">verfasserin</subfield><subfield code="4">aut</subfield></datafield><datafield tag="700" ind1="0" ind2=" "><subfield code="a">Raphaël Veil</subfield><subfield code="e">verfasserin</subfield><subfield code="4">aut</subfield></datafield><datafield tag="700" ind1="0" ind2=" "><subfield code="a">Maxime Fieux</subfield><subfield code="e">verfasserin</subfield><subfield code="4">aut</subfield></datafield><datafield tag="773" ind1="0" ind2="8"><subfield code="i">In</subfield><subfield code="t">Life</subfield><subfield code="d">MDPI AG, 2012</subfield><subfield code="g">14(2024), 3, p 293</subfield><subfield code="w">(DE-627)718627156</subfield><subfield code="w">(DE-600)2662250-6</subfield><subfield code="x">20751729</subfield><subfield code="7">nnns</subfield></datafield><datafield tag="773" ind1="1" ind2="8"><subfield code="g">volume:14</subfield><subfield code="g">year:2024</subfield><subfield code="g">number:3, p 293</subfield></datafield><datafield tag="856" ind1="4" ind2="0"><subfield code="u">https://doi.org/10.3390/life14030293</subfield><subfield code="z">kostenfrei</subfield></datafield><datafield tag="856" ind1="4" ind2="0"><subfield code="u">https://doaj.org/article/483e5d4d89164fbeb9f78d1f473bbd59</subfield><subfield code="z">kostenfrei</subfield></datafield><datafield tag="856" ind1="4" ind2="0"><subfield code="u">https://www.mdpi.com/2075-1729/14/3/293</subfield><subfield code="z">kostenfrei</subfield></datafield><datafield tag="856" ind1="4" ind2="2"><subfield code="u">https://doaj.org/toc/2075-1729</subfield><subfield code="y">Journal toc</subfield><subfield code="z">kostenfrei</subfield></datafield><datafield tag="912" ind1=" " ind2=" "><subfield code="a">GBV_USEFLAG_A</subfield></datafield><datafield tag="912" ind1=" " ind2=" "><subfield code="a">SYSFLAG_A</subfield></datafield><datafield tag="912" ind1=" " ind2=" "><subfield code="a">GBV_DOAJ</subfield></datafield><datafield tag="912" ind1=" " ind2=" "><subfield code="a">GBV_ILN_20</subfield></datafield><datafield tag="912" ind1=" " ind2=" "><subfield code="a">GBV_ILN_22</subfield></datafield><datafield tag="912" ind1=" " ind2=" "><subfield code="a">GBV_ILN_23</subfield></datafield><datafield tag="912" ind1=" " ind2=" "><subfield code="a">GBV_ILN_24</subfield></datafield><datafield tag="912" ind1=" " ind2=" "><subfield code="a">GBV_ILN_31</subfield></datafield><datafield tag="912" ind1=" " ind2=" "><subfield code="a">GBV_ILN_39</subfield></datafield><datafield tag="912" ind1=" " ind2=" "><subfield code="a">GBV_ILN_40</subfield></datafield><datafield tag="912" ind1=" " ind2=" "><subfield code="a">GBV_ILN_62</subfield></datafield><datafield tag="912" ind1=" " ind2=" "><subfield code="a">GBV_ILN_63</subfield></datafield><datafield tag="912" ind1=" " ind2=" "><subfield code="a">GBV_ILN_65</subfield></datafield><datafield tag="912" ind1=" " ind2=" "><subfield code="a">GBV_ILN_69</subfield></datafield><datafield tag="912" ind1=" " ind2=" "><subfield code="a">GBV_ILN_70</subfield></datafield><datafield tag="912" ind1=" " ind2=" "><subfield code="a">GBV_ILN_73</subfield></datafield><datafield tag="912" ind1=" " ind2=" "><subfield code="a">GBV_ILN_74</subfield></datafield><datafield tag="912" ind1=" " ind2=" "><subfield code="a">GBV_ILN_95</subfield></datafield><datafield tag="912" ind1=" " ind2=" "><subfield code="a">GBV_ILN_105</subfield></datafield><datafield tag="912" ind1=" " ind2=" "><subfield code="a">GBV_ILN_110</subfield></datafield><datafield tag="912" ind1=" " ind2=" "><subfield code="a">GBV_ILN_151</subfield></datafield><datafield tag="912" ind1=" " ind2=" "><subfield code="a">GBV_ILN_161</subfield></datafield><datafield tag="912" ind1=" " ind2=" "><subfield code="a">GBV_ILN_170</subfield></datafield><datafield tag="912" ind1=" " ind2=" "><subfield code="a">GBV_ILN_206</subfield></datafield><datafield tag="912" ind1=" " ind2=" "><subfield code="a">GBV_ILN_213</subfield></datafield><datafield tag="912" ind1=" " ind2=" "><subfield code="a">GBV_ILN_230</subfield></datafield><datafield tag="912" ind1=" " ind2=" "><subfield code="a">GBV_ILN_285</subfield></datafield><datafield tag="912" ind1=" " ind2=" "><subfield code="a">GBV_ILN_293</subfield></datafield><datafield tag="912" ind1=" " ind2=" "><subfield code="a">GBV_ILN_602</subfield></datafield><datafield tag="912" ind1=" " ind2=" "><subfield code="a">GBV_ILN_2005</subfield></datafield><datafield tag="912" ind1=" " ind2=" "><subfield code="a">GBV_ILN_2009</subfield></datafield><datafield tag="912" ind1=" " ind2=" "><subfield code="a">GBV_ILN_2011</subfield></datafield><datafield tag="912" ind1=" " ind2=" "><subfield code="a">GBV_ILN_2014</subfield></datafield><datafield tag="912" ind1=" " ind2=" "><subfield code="a">GBV_ILN_2055</subfield></datafield><datafield tag="912" ind1=" " ind2=" "><subfield code="a">GBV_ILN_2111</subfield></datafield><datafield tag="912" ind1=" " ind2=" "><subfield code="a">GBV_ILN_4012</subfield></datafield><datafield tag="912" ind1=" " ind2=" "><subfield code="a">GBV_ILN_4037</subfield></datafield><datafield tag="912" ind1=" " ind2=" "><subfield code="a">GBV_ILN_4112</subfield></datafield><datafield tag="912" ind1=" " ind2=" "><subfield code="a">GBV_ILN_4125</subfield></datafield><datafield tag="912" ind1=" " ind2=" "><subfield code="a">GBV_ILN_4126</subfield></datafield><datafield tag="912" ind1=" " ind2=" "><subfield code="a">GBV_ILN_4249</subfield></datafield><datafield tag="912" ind1=" " ind2=" "><subfield code="a">GBV_ILN_4305</subfield></datafield><datafield tag="912" ind1=" " ind2=" "><subfield code="a">GBV_ILN_4306</subfield></datafield><datafield tag="912" ind1=" " ind2=" "><subfield code="a">GBV_ILN_4307</subfield></datafield><datafield tag="912" ind1=" " ind2=" "><subfield code="a">GBV_ILN_4313</subfield></datafield><datafield tag="912" ind1=" " ind2=" "><subfield code="a">GBV_ILN_4322</subfield></datafield><datafield tag="912" ind1=" " ind2=" "><subfield code="a">GBV_ILN_4323</subfield></datafield><datafield tag="912" ind1=" " ind2=" "><subfield code="a">GBV_ILN_4324</subfield></datafield><datafield tag="912" ind1=" " ind2=" "><subfield code="a">GBV_ILN_4325</subfield></datafield><datafield tag="912" ind1=" " ind2=" "><subfield code="a">GBV_ILN_4338</subfield></datafield><datafield tag="912" ind1=" " ind2=" "><subfield code="a">GBV_ILN_4367</subfield></datafield><datafield tag="912" ind1=" " ind2=" "><subfield code="a">GBV_ILN_4700</subfield></datafield><datafield tag="951" ind1=" " ind2=" "><subfield code="a">AR</subfield></datafield><datafield tag="952" ind1=" " ind2=" "><subfield code="d">14</subfield><subfield code="j">2024</subfield><subfield code="e">3, p 293</subfield></datafield></record></collection>
|
| score |
7.400361 |