Stem cell-derived embryo models: a frontier of human embryology

Studying human development remains difficult due to limited accessibility to human embryonic tissues. Prompted by the availability of human stem cells that share molecular and cellular similarities with embryonic and extraembryonic cells in peri-implantation human embryos, researchers have now succe...
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Autor*in:	Kobayashi Norio [verfasserIn] Fu Jianping [verfasserIn]

Format:	E-Artikel
Sprache:	Englisch

Erschienen:	2023

Schlagwörter:	embryo models embryonic development pluripotent stem cells

Übergeordnetes Werk:	In: Medical Review - De Gruyter, 2022, 3(2023), 4, Seite 343-346
Übergeordnetes Werk:	volume:3 ; year:2023 ; number:4 ; pages:343-346

Links:	Link aufrufen Link aufrufen Link aufrufen Journal toc

DOI / URN:	10.1515/mr-2023-0009

Katalog-ID:	DOAJ100721559

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author	Kobayashi Norio
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title	Stem cell-derived embryo models: a frontier of human embryology
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title_full	Stem cell-derived embryo models: a frontier of human embryology
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title_sort	stem cell-derived embryo models: a frontier of human embryology
title_auth	Stem cell-derived embryo models: a frontier of human embryology
abstract	Studying human development remains difficult due to limited accessibility to human embryonic tissues. Prompted by the availability of human stem cells that share molecular and cellular similarities with embryonic and extraembryonic cells in peri-implantation human embryos, researchers have now successfully developed stem cell-based human embryo models that are promising as experimental tools for studying early human development. In this Perspective, we discuss the current progress in mouse and human stem cell-derived embryo models and highlight their promising applications in advancing the fundamental understanding of mammalian development.
abstractGer	Studying human development remains difficult due to limited accessibility to human embryonic tissues. Prompted by the availability of human stem cells that share molecular and cellular similarities with embryonic and extraembryonic cells in peri-implantation human embryos, researchers have now successfully developed stem cell-based human embryo models that are promising as experimental tools for studying early human development. In this Perspective, we discuss the current progress in mouse and human stem cell-derived embryo models and highlight their promising applications in advancing the fundamental understanding of mammalian development.
abstract_unstemmed	Studying human development remains difficult due to limited accessibility to human embryonic tissues. Prompted by the availability of human stem cells that share molecular and cellular similarities with embryonic and extraembryonic cells in peri-implantation human embryos, researchers have now successfully developed stem cell-based human embryo models that are promising as experimental tools for studying early human development. In this Perspective, we discuss the current progress in mouse and human stem cell-derived embryo models and highlight their promising applications in advancing the fundamental understanding of mammalian development.
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title_short	Stem cell-derived embryo models: a frontier of human embryology
url	https://doi.org/10.1515/mr-2023-0009 https://doaj.org/article/af29d526cee84bb4b6c2dbd509776f8a https://doaj.org/toc/2749-9642
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up_date	2024-07-03T16:18:55.215Z
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