Preparation of Nanosized Pharmaceutical Formulations by Dual Centrifugation

Dual centrifugation (DC) is an innovative in-vial homogenization and in-vial nanomilling technique that has been in use for the preparation of liposomes for more than one decade. Since then, DC has continuously been developed for preparing various liposomes and other lipid nanoparticles including em...
Ausführliche Beschreibung

Gespeichert in:

Autor*in:	Jonas K. Koehler [verfasserIn] Stefanie Schmager [verfasserIn] Valentin Bender [verfasserIn] Denise Steiner [verfasserIn] Ulrich Massing [verfasserIn]

Format:	E-Artikel
Sprache:	Englisch

Erschienen:	2023

Schlagwörter:	dual centrifugation dual asymmetric centrifugation homogenization lipid nanoparticles liposomes polymersomes

Übergeordnetes Werk:	In: Pharmaceuticals - MDPI AG, 2005, 16(2023), 11, p 1519
Übergeordnetes Werk:	volume:16 ; year:2023 ; number:11, p 1519

Links:	Link aufrufen Link aufrufen Link aufrufen Journal toc

DOI / URN:	10.3390/ph16111519

Katalog-ID:	DOAJ10120258X

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spelling	10.3390/ph16111519 doi (DE-627)DOAJ10120258X (DE-599)DOAJ230afd8df52f49d098d4285f908a598f DE-627 ger DE-627 rakwb eng RS1-441 Jonas K. Koehler verfasserin aut Preparation of Nanosized Pharmaceutical Formulations by Dual Centrifugation 2023 Text txt rdacontent Computermedien c rdamedia Online-Ressource cr rdacarrier Dual centrifugation (DC) is an innovative in-vial homogenization and in-vial nanomilling technique that has been in use for the preparation of liposomes for more than one decade. Since then, DC has continuously been developed for preparing various liposomes and other lipid nanoparticles including emulsions and solid lipid nanoparticles (SLNs) as well as polymersomes and nanocrystals. Improvements in equipment technology have been achieved over the past decade, so that DC is now on its way to becoming the <i<quasi</i<-standard for the simple, fast, and aseptic production of lipid nanoparticles and nanocrystals in small and medium batch sizes, including the possibility of simple and fast formulation screening or bedside preparations of therapeutic nanoparticles. More than 68 publications in which DC was used to produce nanoparticles have appeared since then, justifying an initial review of the use of DC for pharmaceutical nanotechnology. dual centrifugation dual asymmetric centrifugation homogenization lipid nanoparticles liposomes polymersomes Medicine R Pharmacy and materia medica Stefanie Schmager verfasserin aut Valentin Bender verfasserin aut Denise Steiner verfasserin aut Ulrich Massing verfasserin aut In Pharmaceuticals MDPI AG, 2005 16(2023), 11, p 1519 (DE-627)491437528 (DE-600)2193542-7 14248247 nnns volume:16 year:2023 number:11, p 1519 https://doi.org/10.3390/ph16111519 kostenfrei https://doaj.org/article/230afd8df52f49d098d4285f908a598f kostenfrei https://www.mdpi.com/1424-8247/16/11/1519 kostenfrei https://doaj.org/toc/1424-8247 Journal toc kostenfrei GBV_USEFLAG_A SYSFLAG_A GBV_DOAJ GBV_ILN_20 GBV_ILN_22 GBV_ILN_23 GBV_ILN_24 GBV_ILN_39 GBV_ILN_40 GBV_ILN_60 GBV_ILN_62 GBV_ILN_63 GBV_ILN_65 GBV_ILN_69 GBV_ILN_73 GBV_ILN_74 GBV_ILN_95 GBV_ILN_105 GBV_ILN_110 GBV_ILN_151 GBV_ILN_161 GBV_ILN_170 GBV_ILN_206 GBV_ILN_213 GBV_ILN_230 GBV_ILN_285 GBV_ILN_293 GBV_ILN_602 GBV_ILN_2005 GBV_ILN_2009 GBV_ILN_2011 GBV_ILN_2014 GBV_ILN_2055 GBV_ILN_2111 GBV_ILN_4012 GBV_ILN_4037 GBV_ILN_4112 GBV_ILN_4125 GBV_ILN_4126 GBV_ILN_4249 GBV_ILN_4305 GBV_ILN_4306 GBV_ILN_4307 GBV_ILN_4313 GBV_ILN_4322 GBV_ILN_4323 GBV_ILN_4324 GBV_ILN_4325 GBV_ILN_4338 GBV_ILN_4367 GBV_ILN_4700 AR 16 2023 11, p 1519
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allfieldsGer	10.3390/ph16111519 doi (DE-627)DOAJ10120258X (DE-599)DOAJ230afd8df52f49d098d4285f908a598f DE-627 ger DE-627 rakwb eng RS1-441 Jonas K. Koehler verfasserin aut Preparation of Nanosized Pharmaceutical Formulations by Dual Centrifugation 2023 Text txt rdacontent Computermedien c rdamedia Online-Ressource cr rdacarrier Dual centrifugation (DC) is an innovative in-vial homogenization and in-vial nanomilling technique that has been in use for the preparation of liposomes for more than one decade. Since then, DC has continuously been developed for preparing various liposomes and other lipid nanoparticles including emulsions and solid lipid nanoparticles (SLNs) as well as polymersomes and nanocrystals. Improvements in equipment technology have been achieved over the past decade, so that DC is now on its way to becoming the <i<quasi</i<-standard for the simple, fast, and aseptic production of lipid nanoparticles and nanocrystals in small and medium batch sizes, including the possibility of simple and fast formulation screening or bedside preparations of therapeutic nanoparticles. More than 68 publications in which DC was used to produce nanoparticles have appeared since then, justifying an initial review of the use of DC for pharmaceutical nanotechnology. dual centrifugation dual asymmetric centrifugation homogenization lipid nanoparticles liposomes polymersomes Medicine R Pharmacy and materia medica Stefanie Schmager verfasserin aut Valentin Bender verfasserin aut Denise Steiner verfasserin aut Ulrich Massing verfasserin aut In Pharmaceuticals MDPI AG, 2005 16(2023), 11, p 1519 (DE-627)491437528 (DE-600)2193542-7 14248247 nnns volume:16 year:2023 number:11, p 1519 https://doi.org/10.3390/ph16111519 kostenfrei https://doaj.org/article/230afd8df52f49d098d4285f908a598f kostenfrei https://www.mdpi.com/1424-8247/16/11/1519 kostenfrei https://doaj.org/toc/1424-8247 Journal toc kostenfrei GBV_USEFLAG_A SYSFLAG_A GBV_DOAJ GBV_ILN_20 GBV_ILN_22 GBV_ILN_23 GBV_ILN_24 GBV_ILN_39 GBV_ILN_40 GBV_ILN_60 GBV_ILN_62 GBV_ILN_63 GBV_ILN_65 GBV_ILN_69 GBV_ILN_73 GBV_ILN_74 GBV_ILN_95 GBV_ILN_105 GBV_ILN_110 GBV_ILN_151 GBV_ILN_161 GBV_ILN_170 GBV_ILN_206 GBV_ILN_213 GBV_ILN_230 GBV_ILN_285 GBV_ILN_293 GBV_ILN_602 GBV_ILN_2005 GBV_ILN_2009 GBV_ILN_2011 GBV_ILN_2014 GBV_ILN_2055 GBV_ILN_2111 GBV_ILN_4012 GBV_ILN_4037 GBV_ILN_4112 GBV_ILN_4125 GBV_ILN_4126 GBV_ILN_4249 GBV_ILN_4305 GBV_ILN_4306 GBV_ILN_4307 GBV_ILN_4313 GBV_ILN_4322 GBV_ILN_4323 GBV_ILN_4324 GBV_ILN_4325 GBV_ILN_4338 GBV_ILN_4367 GBV_ILN_4700 AR 16 2023 11, p 1519
allfieldsSound	10.3390/ph16111519 doi (DE-627)DOAJ10120258X (DE-599)DOAJ230afd8df52f49d098d4285f908a598f DE-627 ger DE-627 rakwb eng RS1-441 Jonas K. Koehler verfasserin aut Preparation of Nanosized Pharmaceutical Formulations by Dual Centrifugation 2023 Text txt rdacontent Computermedien c rdamedia Online-Ressource cr rdacarrier Dual centrifugation (DC) is an innovative in-vial homogenization and in-vial nanomilling technique that has been in use for the preparation of liposomes for more than one decade. Since then, DC has continuously been developed for preparing various liposomes and other lipid nanoparticles including emulsions and solid lipid nanoparticles (SLNs) as well as polymersomes and nanocrystals. Improvements in equipment technology have been achieved over the past decade, so that DC is now on its way to becoming the <i<quasi</i<-standard for the simple, fast, and aseptic production of lipid nanoparticles and nanocrystals in small and medium batch sizes, including the possibility of simple and fast formulation screening or bedside preparations of therapeutic nanoparticles. More than 68 publications in which DC was used to produce nanoparticles have appeared since then, justifying an initial review of the use of DC for pharmaceutical nanotechnology. dual centrifugation dual asymmetric centrifugation homogenization lipid nanoparticles liposomes polymersomes Medicine R Pharmacy and materia medica Stefanie Schmager verfasserin aut Valentin Bender verfasserin aut Denise Steiner verfasserin aut Ulrich Massing verfasserin aut In Pharmaceuticals MDPI AG, 2005 16(2023), 11, p 1519 (DE-627)491437528 (DE-600)2193542-7 14248247 nnns volume:16 year:2023 number:11, p 1519 https://doi.org/10.3390/ph16111519 kostenfrei https://doaj.org/article/230afd8df52f49d098d4285f908a598f kostenfrei https://www.mdpi.com/1424-8247/16/11/1519 kostenfrei https://doaj.org/toc/1424-8247 Journal toc kostenfrei GBV_USEFLAG_A SYSFLAG_A GBV_DOAJ GBV_ILN_20 GBV_ILN_22 GBV_ILN_23 GBV_ILN_24 GBV_ILN_39 GBV_ILN_40 GBV_ILN_60 GBV_ILN_62 GBV_ILN_63 GBV_ILN_65 GBV_ILN_69 GBV_ILN_73 GBV_ILN_74 GBV_ILN_95 GBV_ILN_105 GBV_ILN_110 GBV_ILN_151 GBV_ILN_161 GBV_ILN_170 GBV_ILN_206 GBV_ILN_213 GBV_ILN_230 GBV_ILN_285 GBV_ILN_293 GBV_ILN_602 GBV_ILN_2005 GBV_ILN_2009 GBV_ILN_2011 GBV_ILN_2014 GBV_ILN_2055 GBV_ILN_2111 GBV_ILN_4012 GBV_ILN_4037 GBV_ILN_4112 GBV_ILN_4125 GBV_ILN_4126 GBV_ILN_4249 GBV_ILN_4305 GBV_ILN_4306 GBV_ILN_4307 GBV_ILN_4313 GBV_ILN_4322 GBV_ILN_4323 GBV_ILN_4324 GBV_ILN_4325 GBV_ILN_4338 GBV_ILN_4367 GBV_ILN_4700 AR 16 2023 11, p 1519
language	English
source	In Pharmaceuticals 16(2023), 11, p 1519 volume:16 year:2023 number:11, p 1519
sourceStr	In Pharmaceuticals 16(2023), 11, p 1519 volume:16 year:2023 number:11, p 1519
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topic_facet	dual centrifugation dual asymmetric centrifugation homogenization lipid nanoparticles liposomes polymersomes Medicine R Pharmacy and materia medica
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callnumber-first	R - Medicine
author	Jonas K. Koehler
spellingShingle	Jonas K. Koehler misc RS1-441 misc dual centrifugation misc dual asymmetric centrifugation misc homogenization misc lipid nanoparticles misc liposomes misc polymersomes misc Medicine misc R misc Pharmacy and materia medica Preparation of Nanosized Pharmaceutical Formulations by Dual Centrifugation
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topic_title	RS1-441 Preparation of Nanosized Pharmaceutical Formulations by Dual Centrifugation dual centrifugation dual asymmetric centrifugation homogenization lipid nanoparticles liposomes polymersomes
topic	misc RS1-441 misc dual centrifugation misc dual asymmetric centrifugation misc homogenization misc lipid nanoparticles misc liposomes misc polymersomes misc Medicine misc R misc Pharmacy and materia medica
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title	Preparation of Nanosized Pharmaceutical Formulations by Dual Centrifugation
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title_sort	preparation of nanosized pharmaceutical formulations by dual centrifugation
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title_auth	Preparation of Nanosized Pharmaceutical Formulations by Dual Centrifugation
abstract	Dual centrifugation (DC) is an innovative in-vial homogenization and in-vial nanomilling technique that has been in use for the preparation of liposomes for more than one decade. Since then, DC has continuously been developed for preparing various liposomes and other lipid nanoparticles including emulsions and solid lipid nanoparticles (SLNs) as well as polymersomes and nanocrystals. Improvements in equipment technology have been achieved over the past decade, so that DC is now on its way to becoming the <i<quasi</i<-standard for the simple, fast, and aseptic production of lipid nanoparticles and nanocrystals in small and medium batch sizes, including the possibility of simple and fast formulation screening or bedside preparations of therapeutic nanoparticles. More than 68 publications in which DC was used to produce nanoparticles have appeared since then, justifying an initial review of the use of DC for pharmaceutical nanotechnology.
abstractGer	Dual centrifugation (DC) is an innovative in-vial homogenization and in-vial nanomilling technique that has been in use for the preparation of liposomes for more than one decade. Since then, DC has continuously been developed for preparing various liposomes and other lipid nanoparticles including emulsions and solid lipid nanoparticles (SLNs) as well as polymersomes and nanocrystals. Improvements in equipment technology have been achieved over the past decade, so that DC is now on its way to becoming the <i<quasi</i<-standard for the simple, fast, and aseptic production of lipid nanoparticles and nanocrystals in small and medium batch sizes, including the possibility of simple and fast formulation screening or bedside preparations of therapeutic nanoparticles. More than 68 publications in which DC was used to produce nanoparticles have appeared since then, justifying an initial review of the use of DC for pharmaceutical nanotechnology.
abstract_unstemmed	Dual centrifugation (DC) is an innovative in-vial homogenization and in-vial nanomilling technique that has been in use for the preparation of liposomes for more than one decade. Since then, DC has continuously been developed for preparing various liposomes and other lipid nanoparticles including emulsions and solid lipid nanoparticles (SLNs) as well as polymersomes and nanocrystals. Improvements in equipment technology have been achieved over the past decade, so that DC is now on its way to becoming the <i<quasi</i<-standard for the simple, fast, and aseptic production of lipid nanoparticles and nanocrystals in small and medium batch sizes, including the possibility of simple and fast formulation screening or bedside preparations of therapeutic nanoparticles. More than 68 publications in which DC was used to produce nanoparticles have appeared since then, justifying an initial review of the use of DC for pharmaceutical nanotechnology.
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title_short	Preparation of Nanosized Pharmaceutical Formulations by Dual Centrifugation
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Preparation of Nanosized Pharmaceutical Formulations by Dual Centrifugation

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