The Risk of Venous Thromboembolism in Neuroendocrine Neoplasms

Neuroendocrine neoplasms (NENs) differ from other malignancies in their ability to produce hormones and biogenic amines, as well as offer a better prognosis in well-differentiated tumors. There are no definite data on the occurrence of thromboembolic events in NENs and no recommendations regarding t...
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Autor*in:	Monika Wójcik-Giertuga [verfasserIn] Anna Malczewska-Herman [verfasserIn] Beata Kos-Kudła [verfasserIn]

Format:	E-Artikel
Sprache:	Englisch

Erschienen:	2023

Schlagwörter:	venous thromboembolism cancer-associated thrombosis thrombosis neuroendocrine neoplasms thromboembolic risk

Übergeordnetes Werk:	In: Cancers - MDPI AG, 2010, 15(2023), 22, p 5477
Übergeordnetes Werk:	volume:15 ; year:2023 ; number:22, p 5477

Links:	Link aufrufen Link aufrufen Link aufrufen Journal toc

DOI / URN:	10.3390/cancers15225477

Katalog-ID:	DOAJ101262744

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520			\|a Neuroendocrine neoplasms (NENs) differ from other malignancies in their ability to produce hormones and biogenic amines, as well as offer a better prognosis in well-differentiated tumors. There are no definite data on the occurrence of thromboembolic events in NENs and no recommendations regarding the use of antithrombotic prophylaxis in this group. Accurate assessment of the thromboembolic risk in NENs represents an important issue, in order to reduce morbidity and mortality due to complications of VTE. The aim of this work was to review the occurrence of thromboembolic events in NENs and the use of antithrombotic prophylaxis in this group. A total of 28 studies identified on PubMed were analyzed. NENs, especially of pancreatic primary, exhibit an increased thrombotic risk. Atypical VTE locations are quite common in NENs. Hormonally active NENs are associated with a significantly increased thromboembolic risk. Further studies in NENs are needed to evaluate the parameters of coagulation and fibrinolysis as predictive biomarkers for VTE complications.
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language	English
source	In Cancers 15(2023), 22, p 5477 volume:15 year:2023 number:22, p 5477
sourceStr	In Cancers 15(2023), 22, p 5477 volume:15 year:2023 number:22, p 5477
format_phy_str_mv	Article
institution	findex.gbv.de
topic_facet	venous thromboembolism cancer-associated thrombosis thrombosis neuroendocrine neoplasms thromboembolic risk Neoplasms. Tumors. Oncology. Including cancer and carcinogens
isfreeaccess_bool	true
container_title	Cancers
authorswithroles_txt_mv	Monika Wójcik-Giertuga @@aut@@ Anna Malczewska-Herman @@aut@@ Beata Kos-Kudła @@aut@@
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callnumber-first	R - Medicine
author	Monika Wójcik-Giertuga
spellingShingle	Monika Wójcik-Giertuga misc RC254-282 misc venous thromboembolism misc cancer-associated thrombosis misc thrombosis misc neuroendocrine neoplasms misc thromboembolic risk misc Neoplasms. Tumors. Oncology. Including cancer and carcinogens The Risk of Venous Thromboembolism in Neuroendocrine Neoplasms
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topic_title	RC254-282 The Risk of Venous Thromboembolism in Neuroendocrine Neoplasms venous thromboembolism cancer-associated thrombosis thrombosis neuroendocrine neoplasms thromboembolic risk
topic	misc RC254-282 misc venous thromboembolism misc cancer-associated thrombosis misc thrombosis misc neuroendocrine neoplasms misc thromboembolic risk misc Neoplasms. Tumors. Oncology. Including cancer and carcinogens
topic_unstemmed	misc RC254-282 misc venous thromboembolism misc cancer-associated thrombosis misc thrombosis misc neuroendocrine neoplasms misc thromboembolic risk misc Neoplasms. Tumors. Oncology. Including cancer and carcinogens
topic_browse	misc RC254-282 misc venous thromboembolism misc cancer-associated thrombosis misc thrombosis misc neuroendocrine neoplasms misc thromboembolic risk misc Neoplasms. Tumors. Oncology. Including cancer and carcinogens
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title	The Risk of Venous Thromboembolism in Neuroendocrine Neoplasms
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title_full	The Risk of Venous Thromboembolism in Neuroendocrine Neoplasms
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title_sort	risk of venous thromboembolism in neuroendocrine neoplasms
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title_auth	The Risk of Venous Thromboembolism in Neuroendocrine Neoplasms
abstract	Neuroendocrine neoplasms (NENs) differ from other malignancies in their ability to produce hormones and biogenic amines, as well as offer a better prognosis in well-differentiated tumors. There are no definite data on the occurrence of thromboembolic events in NENs and no recommendations regarding the use of antithrombotic prophylaxis in this group. Accurate assessment of the thromboembolic risk in NENs represents an important issue, in order to reduce morbidity and mortality due to complications of VTE. The aim of this work was to review the occurrence of thromboembolic events in NENs and the use of antithrombotic prophylaxis in this group. A total of 28 studies identified on PubMed were analyzed. NENs, especially of pancreatic primary, exhibit an increased thrombotic risk. Atypical VTE locations are quite common in NENs. Hormonally active NENs are associated with a significantly increased thromboembolic risk. Further studies in NENs are needed to evaluate the parameters of coagulation and fibrinolysis as predictive biomarkers for VTE complications.
abstractGer	Neuroendocrine neoplasms (NENs) differ from other malignancies in their ability to produce hormones and biogenic amines, as well as offer a better prognosis in well-differentiated tumors. There are no definite data on the occurrence of thromboembolic events in NENs and no recommendations regarding the use of antithrombotic prophylaxis in this group. Accurate assessment of the thromboembolic risk in NENs represents an important issue, in order to reduce morbidity and mortality due to complications of VTE. The aim of this work was to review the occurrence of thromboembolic events in NENs and the use of antithrombotic prophylaxis in this group. A total of 28 studies identified on PubMed were analyzed. NENs, especially of pancreatic primary, exhibit an increased thrombotic risk. Atypical VTE locations are quite common in NENs. Hormonally active NENs are associated with a significantly increased thromboembolic risk. Further studies in NENs are needed to evaluate the parameters of coagulation and fibrinolysis as predictive biomarkers for VTE complications.
abstract_unstemmed	Neuroendocrine neoplasms (NENs) differ from other malignancies in their ability to produce hormones and biogenic amines, as well as offer a better prognosis in well-differentiated tumors. There are no definite data on the occurrence of thromboembolic events in NENs and no recommendations regarding the use of antithrombotic prophylaxis in this group. Accurate assessment of the thromboembolic risk in NENs represents an important issue, in order to reduce morbidity and mortality due to complications of VTE. The aim of this work was to review the occurrence of thromboembolic events in NENs and the use of antithrombotic prophylaxis in this group. A total of 28 studies identified on PubMed were analyzed. NENs, especially of pancreatic primary, exhibit an increased thrombotic risk. Atypical VTE locations are quite common in NENs. Hormonally active NENs are associated with a significantly increased thromboembolic risk. Further studies in NENs are needed to evaluate the parameters of coagulation and fibrinolysis as predictive biomarkers for VTE complications.
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title_short	The Risk of Venous Thromboembolism in Neuroendocrine Neoplasms
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The Risk of Venous Thromboembolism in Neuroendocrine Neoplasms

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