Midterm follow-up of composite graft replacement of the aortic root (30-year experience)—remarkably safe, effective, and durableCentral MessagePerspective

Objectives: Contemporary operative choices for aortic root disease include aortic root replacement (ARR) and a variety of valve-sparing and aortic root-repair procedures. We evaluate ultra-long-term outcomes of ARR, focusing on survival, freedom from late reoperation, and adverse events. Methods: Pr...
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Autor*in:	Syeda Manahil Haider Jeoffrey, MD [verfasserIn] Mohammad A. Zafar, MBBS [verfasserIn] Juan Velasco, MD [verfasserIn] Ahad Khattak, MD [verfasserIn] Hesham Ellauzi, MB BCh, BAO (hons) [verfasserIn] Afsheen Nasir, MD [verfasserIn] Asanish Kalyanasundaram, MD [verfasserIn] Bulat A. Ziganshin, MD, PhD [verfasserIn] John A. Elefteriades, MD, PhD (Hon) [verfasserIn]

Format:	E-Artikel
Sprache:	Englisch

Erschienen:	2024

Schlagwörter:	composite aortic graft Cabrol procedure aortic root repair valve sparing Dacron coronary graft aortic root replacement

Übergeordnetes Werk:	In: JTCVS Open - Elsevier, 2022, 17(2024), Seite 13
Übergeordnetes Werk:	volume:17 ; year:2024 ; pages:13

Links:	Link aufrufen Link aufrufen Link aufrufen Journal toc

DOI / URN:	10.1016/j.xjon.2023.11.007

Katalog-ID:	DOAJ101352255

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520			\|a Objectives: Contemporary operative choices for aortic root disease include aortic root replacement (ARR) and a variety of valve-sparing and aortic root-repair procedures. We evaluate ultra-long-term outcomes of ARR, focusing on survival, freedom from late reoperation, and adverse events. Methods: Prospectively kept records were used to accomplish long-term follow-up of patients who underwent ARR (4-pronged Yale survival assessment paradigm). Results: Between 1990 and 2020, 564 patients underwent ARR (mean 56 years, 84% male). A modified Cabrol procedure (Dacron coronary graft) was employed in 9.0% (51/564) and concomitant coronary artery bypass grafting in 9.4% (53/564). There were 12.8% (72/564) urgent/emergent and 7.4% (42/564) redo procedures. Operative mortality occurred in 12 patients (2.1%) overall, or 1.4% (8/554) of nondissection and 1.3% (6/468) of elective first-time operations. Six of the 12 deaths presented with acute type A dissection, urgent operation, or reoperative states. Operative mortality dropped to 0.6% during the past 10 years. In total, 11 patients developed endocarditis. Stroke occurred in 11 of 564 patients (2.0%), 4 of whom had presented with type A dissection. Late events included bleeding in 2.8% (16/564), thromboembolism in 1.4% (8/564), and reoperation of the root in 5 of 564 (0.9%) at 15 years and more distal aortic segments in 16/564 (2.8%). Survival was no different from age/sex-matched controls. Conclusions: This ultra-long-term experience finds ARR to be extraordinarily safe, effective, and durable, with minimal long-term bleeding, thromboembolism, or graft failure. This experience provides a standard of durability for ARR against which ultra-long-term outcomes with alternate procedures (valve-sparing, Ross, other) may be compared.
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allfields	10.1016/j.xjon.2023.11.007 doi (DE-627)DOAJ101352255 (DE-599)DOAJ0b89659f136949e0931ecde398152005 DE-627 ger DE-627 rakwb eng RC666-701 RD1-811 Syeda Manahil Haider Jeoffrey, MD verfasserin aut Midterm follow-up of composite graft replacement of the aortic root (30-year experience)—remarkably safe, effective, and durableCentral MessagePerspective 2024 Text txt rdacontent Computermedien c rdamedia Online-Ressource cr rdacarrier Objectives: Contemporary operative choices for aortic root disease include aortic root replacement (ARR) and a variety of valve-sparing and aortic root-repair procedures. We evaluate ultra-long-term outcomes of ARR, focusing on survival, freedom from late reoperation, and adverse events. Methods: Prospectively kept records were used to accomplish long-term follow-up of patients who underwent ARR (4-pronged Yale survival assessment paradigm). Results: Between 1990 and 2020, 564 patients underwent ARR (mean 56 years, 84% male). A modified Cabrol procedure (Dacron coronary graft) was employed in 9.0% (51/564) and concomitant coronary artery bypass grafting in 9.4% (53/564). There were 12.8% (72/564) urgent/emergent and 7.4% (42/564) redo procedures. Operative mortality occurred in 12 patients (2.1%) overall, or 1.4% (8/554) of nondissection and 1.3% (6/468) of elective first-time operations. Six of the 12 deaths presented with acute type A dissection, urgent operation, or reoperative states. Operative mortality dropped to 0.6% during the past 10 years. In total, 11 patients developed endocarditis. Stroke occurred in 11 of 564 patients (2.0%), 4 of whom had presented with type A dissection. Late events included bleeding in 2.8% (16/564), thromboembolism in 1.4% (8/564), and reoperation of the root in 5 of 564 (0.9%) at 15 years and more distal aortic segments in 16/564 (2.8%). Survival was no different from age/sex-matched controls. Conclusions: This ultra-long-term experience finds ARR to be extraordinarily safe, effective, and durable, with minimal long-term bleeding, thromboembolism, or graft failure. This experience provides a standard of durability for ARR against which ultra-long-term outcomes with alternate procedures (valve-sparing, Ross, other) may be compared. composite aortic graft Cabrol procedure aortic root repair valve sparing Dacron coronary graft aortic root replacement Diseases of the circulatory (Cardiovascular) system Surgery Mohammad A. Zafar, MBBS verfasserin aut Juan Velasco, MD verfasserin aut Ahad Khattak, MD verfasserin aut Hesham Ellauzi, MB BCh, BAO (hons) verfasserin aut Afsheen Nasir, MD verfasserin aut Asanish Kalyanasundaram, MD verfasserin aut Bulat A. Ziganshin, MD, PhD verfasserin aut John A. Elefteriades, MD, PhD (Hon) verfasserin aut In JTCVS Open Elsevier, 2022 17(2024), Seite 13 (DE-627)1702642518 26662736 nnns volume:17 year:2024 pages:13 https://doi.org/10.1016/j.xjon.2023.11.007 kostenfrei https://doaj.org/article/0b89659f136949e0931ecde398152005 kostenfrei http://www.sciencedirect.com/science/article/pii/S2666273623003601 kostenfrei https://doaj.org/toc/2666-2736 Journal toc kostenfrei GBV_USEFLAG_A SYSFLAG_A GBV_DOAJ GBV_ILN_20 GBV_ILN_22 GBV_ILN_23 GBV_ILN_24 GBV_ILN_31 GBV_ILN_39 GBV_ILN_40 GBV_ILN_60 GBV_ILN_62 GBV_ILN_63 GBV_ILN_65 GBV_ILN_69 GBV_ILN_73 GBV_ILN_74 GBV_ILN_95 GBV_ILN_105 GBV_ILN_110 GBV_ILN_151 GBV_ILN_161 GBV_ILN_170 GBV_ILN_206 GBV_ILN_213 GBV_ILN_224 GBV_ILN_230 GBV_ILN_285 GBV_ILN_293 GBV_ILN_602 GBV_ILN_2001 GBV_ILN_2003 GBV_ILN_2005 GBV_ILN_2006 GBV_ILN_2007 GBV_ILN_2008 GBV_ILN_2009 GBV_ILN_2010 GBV_ILN_2011 GBV_ILN_2014 GBV_ILN_2015 GBV_ILN_2020 GBV_ILN_2021 GBV_ILN_2025 GBV_ILN_2026 GBV_ILN_2027 GBV_ILN_2034 GBV_ILN_2038 GBV_ILN_2044 GBV_ILN_2048 GBV_ILN_2049 GBV_ILN_2050 GBV_ILN_2055 GBV_ILN_2056 GBV_ILN_2059 GBV_ILN_2061 GBV_ILN_2064 GBV_ILN_2088 GBV_ILN_2106 GBV_ILN_2110 GBV_ILN_2112 GBV_ILN_2122 GBV_ILN_2129 GBV_ILN_2143 GBV_ILN_2152 GBV_ILN_2153 GBV_ILN_2190 GBV_ILN_2232 GBV_ILN_2336 GBV_ILN_2470 GBV_ILN_2507 GBV_ILN_4012 GBV_ILN_4035 GBV_ILN_4037 GBV_ILN_4112 GBV_ILN_4125 GBV_ILN_4126 GBV_ILN_4242 GBV_ILN_4249 GBV_ILN_4251 GBV_ILN_4305 GBV_ILN_4306 GBV_ILN_4307 GBV_ILN_4313 GBV_ILN_4322 GBV_ILN_4323 GBV_ILN_4324 GBV_ILN_4325 GBV_ILN_4326 GBV_ILN_4333 GBV_ILN_4334 GBV_ILN_4338 GBV_ILN_4367 GBV_ILN_4393 GBV_ILN_4700 AR 17 2024 13
spelling	10.1016/j.xjon.2023.11.007 doi (DE-627)DOAJ101352255 (DE-599)DOAJ0b89659f136949e0931ecde398152005 DE-627 ger DE-627 rakwb eng RC666-701 RD1-811 Syeda Manahil Haider Jeoffrey, MD verfasserin aut Midterm follow-up of composite graft replacement of the aortic root (30-year experience)—remarkably safe, effective, and durableCentral MessagePerspective 2024 Text txt rdacontent Computermedien c rdamedia Online-Ressource cr rdacarrier Objectives: Contemporary operative choices for aortic root disease include aortic root replacement (ARR) and a variety of valve-sparing and aortic root-repair procedures. We evaluate ultra-long-term outcomes of ARR, focusing on survival, freedom from late reoperation, and adverse events. Methods: Prospectively kept records were used to accomplish long-term follow-up of patients who underwent ARR (4-pronged Yale survival assessment paradigm). Results: Between 1990 and 2020, 564 patients underwent ARR (mean 56 years, 84% male). A modified Cabrol procedure (Dacron coronary graft) was employed in 9.0% (51/564) and concomitant coronary artery bypass grafting in 9.4% (53/564). There were 12.8% (72/564) urgent/emergent and 7.4% (42/564) redo procedures. Operative mortality occurred in 12 patients (2.1%) overall, or 1.4% (8/554) of nondissection and 1.3% (6/468) of elective first-time operations. Six of the 12 deaths presented with acute type A dissection, urgent operation, or reoperative states. Operative mortality dropped to 0.6% during the past 10 years. In total, 11 patients developed endocarditis. Stroke occurred in 11 of 564 patients (2.0%), 4 of whom had presented with type A dissection. Late events included bleeding in 2.8% (16/564), thromboembolism in 1.4% (8/564), and reoperation of the root in 5 of 564 (0.9%) at 15 years and more distal aortic segments in 16/564 (2.8%). Survival was no different from age/sex-matched controls. Conclusions: This ultra-long-term experience finds ARR to be extraordinarily safe, effective, and durable, with minimal long-term bleeding, thromboembolism, or graft failure. This experience provides a standard of durability for ARR against which ultra-long-term outcomes with alternate procedures (valve-sparing, Ross, other) may be compared. composite aortic graft Cabrol procedure aortic root repair valve sparing Dacron coronary graft aortic root replacement Diseases of the circulatory (Cardiovascular) system Surgery Mohammad A. Zafar, MBBS verfasserin aut Juan Velasco, MD verfasserin aut Ahad Khattak, MD verfasserin aut Hesham Ellauzi, MB BCh, BAO (hons) verfasserin aut Afsheen Nasir, MD verfasserin aut Asanish Kalyanasundaram, MD verfasserin aut Bulat A. Ziganshin, MD, PhD verfasserin aut John A. Elefteriades, MD, PhD (Hon) verfasserin aut In JTCVS Open Elsevier, 2022 17(2024), Seite 13 (DE-627)1702642518 26662736 nnns volume:17 year:2024 pages:13 https://doi.org/10.1016/j.xjon.2023.11.007 kostenfrei https://doaj.org/article/0b89659f136949e0931ecde398152005 kostenfrei http://www.sciencedirect.com/science/article/pii/S2666273623003601 kostenfrei https://doaj.org/toc/2666-2736 Journal toc kostenfrei GBV_USEFLAG_A SYSFLAG_A GBV_DOAJ GBV_ILN_20 GBV_ILN_22 GBV_ILN_23 GBV_ILN_24 GBV_ILN_31 GBV_ILN_39 GBV_ILN_40 GBV_ILN_60 GBV_ILN_62 GBV_ILN_63 GBV_ILN_65 GBV_ILN_69 GBV_ILN_73 GBV_ILN_74 GBV_ILN_95 GBV_ILN_105 GBV_ILN_110 GBV_ILN_151 GBV_ILN_161 GBV_ILN_170 GBV_ILN_206 GBV_ILN_213 GBV_ILN_224 GBV_ILN_230 GBV_ILN_285 GBV_ILN_293 GBV_ILN_602 GBV_ILN_2001 GBV_ILN_2003 GBV_ILN_2005 GBV_ILN_2006 GBV_ILN_2007 GBV_ILN_2008 GBV_ILN_2009 GBV_ILN_2010 GBV_ILN_2011 GBV_ILN_2014 GBV_ILN_2015 GBV_ILN_2020 GBV_ILN_2021 GBV_ILN_2025 GBV_ILN_2026 GBV_ILN_2027 GBV_ILN_2034 GBV_ILN_2038 GBV_ILN_2044 GBV_ILN_2048 GBV_ILN_2049 GBV_ILN_2050 GBV_ILN_2055 GBV_ILN_2056 GBV_ILN_2059 GBV_ILN_2061 GBV_ILN_2064 GBV_ILN_2088 GBV_ILN_2106 GBV_ILN_2110 GBV_ILN_2112 GBV_ILN_2122 GBV_ILN_2129 GBV_ILN_2143 GBV_ILN_2152 GBV_ILN_2153 GBV_ILN_2190 GBV_ILN_2232 GBV_ILN_2336 GBV_ILN_2470 GBV_ILN_2507 GBV_ILN_4012 GBV_ILN_4035 GBV_ILN_4037 GBV_ILN_4112 GBV_ILN_4125 GBV_ILN_4126 GBV_ILN_4242 GBV_ILN_4249 GBV_ILN_4251 GBV_ILN_4305 GBV_ILN_4306 GBV_ILN_4307 GBV_ILN_4313 GBV_ILN_4322 GBV_ILN_4323 GBV_ILN_4324 GBV_ILN_4325 GBV_ILN_4326 GBV_ILN_4333 GBV_ILN_4334 GBV_ILN_4338 GBV_ILN_4367 GBV_ILN_4393 GBV_ILN_4700 AR 17 2024 13
allfields_unstemmed	10.1016/j.xjon.2023.11.007 doi (DE-627)DOAJ101352255 (DE-599)DOAJ0b89659f136949e0931ecde398152005 DE-627 ger DE-627 rakwb eng RC666-701 RD1-811 Syeda Manahil Haider Jeoffrey, MD verfasserin aut Midterm follow-up of composite graft replacement of the aortic root (30-year experience)—remarkably safe, effective, and durableCentral MessagePerspective 2024 Text txt rdacontent Computermedien c rdamedia Online-Ressource cr rdacarrier Objectives: Contemporary operative choices for aortic root disease include aortic root replacement (ARR) and a variety of valve-sparing and aortic root-repair procedures. We evaluate ultra-long-term outcomes of ARR, focusing on survival, freedom from late reoperation, and adverse events. Methods: Prospectively kept records were used to accomplish long-term follow-up of patients who underwent ARR (4-pronged Yale survival assessment paradigm). Results: Between 1990 and 2020, 564 patients underwent ARR (mean 56 years, 84% male). A modified Cabrol procedure (Dacron coronary graft) was employed in 9.0% (51/564) and concomitant coronary artery bypass grafting in 9.4% (53/564). There were 12.8% (72/564) urgent/emergent and 7.4% (42/564) redo procedures. Operative mortality occurred in 12 patients (2.1%) overall, or 1.4% (8/554) of nondissection and 1.3% (6/468) of elective first-time operations. Six of the 12 deaths presented with acute type A dissection, urgent operation, or reoperative states. Operative mortality dropped to 0.6% during the past 10 years. In total, 11 patients developed endocarditis. Stroke occurred in 11 of 564 patients (2.0%), 4 of whom had presented with type A dissection. Late events included bleeding in 2.8% (16/564), thromboembolism in 1.4% (8/564), and reoperation of the root in 5 of 564 (0.9%) at 15 years and more distal aortic segments in 16/564 (2.8%). Survival was no different from age/sex-matched controls. Conclusions: This ultra-long-term experience finds ARR to be extraordinarily safe, effective, and durable, with minimal long-term bleeding, thromboembolism, or graft failure. This experience provides a standard of durability for ARR against which ultra-long-term outcomes with alternate procedures (valve-sparing, Ross, other) may be compared. composite aortic graft Cabrol procedure aortic root repair valve sparing Dacron coronary graft aortic root replacement Diseases of the circulatory (Cardiovascular) system Surgery Mohammad A. Zafar, MBBS verfasserin aut Juan Velasco, MD verfasserin aut Ahad Khattak, MD verfasserin aut Hesham Ellauzi, MB BCh, BAO (hons) verfasserin aut Afsheen Nasir, MD verfasserin aut Asanish Kalyanasundaram, MD verfasserin aut Bulat A. Ziganshin, MD, PhD verfasserin aut John A. Elefteriades, MD, PhD (Hon) verfasserin aut In JTCVS Open Elsevier, 2022 17(2024), Seite 13 (DE-627)1702642518 26662736 nnns volume:17 year:2024 pages:13 https://doi.org/10.1016/j.xjon.2023.11.007 kostenfrei https://doaj.org/article/0b89659f136949e0931ecde398152005 kostenfrei http://www.sciencedirect.com/science/article/pii/S2666273623003601 kostenfrei https://doaj.org/toc/2666-2736 Journal toc kostenfrei GBV_USEFLAG_A SYSFLAG_A GBV_DOAJ GBV_ILN_20 GBV_ILN_22 GBV_ILN_23 GBV_ILN_24 GBV_ILN_31 GBV_ILN_39 GBV_ILN_40 GBV_ILN_60 GBV_ILN_62 GBV_ILN_63 GBV_ILN_65 GBV_ILN_69 GBV_ILN_73 GBV_ILN_74 GBV_ILN_95 GBV_ILN_105 GBV_ILN_110 GBV_ILN_151 GBV_ILN_161 GBV_ILN_170 GBV_ILN_206 GBV_ILN_213 GBV_ILN_224 GBV_ILN_230 GBV_ILN_285 GBV_ILN_293 GBV_ILN_602 GBV_ILN_2001 GBV_ILN_2003 GBV_ILN_2005 GBV_ILN_2006 GBV_ILN_2007 GBV_ILN_2008 GBV_ILN_2009 GBV_ILN_2010 GBV_ILN_2011 GBV_ILN_2014 GBV_ILN_2015 GBV_ILN_2020 GBV_ILN_2021 GBV_ILN_2025 GBV_ILN_2026 GBV_ILN_2027 GBV_ILN_2034 GBV_ILN_2038 GBV_ILN_2044 GBV_ILN_2048 GBV_ILN_2049 GBV_ILN_2050 GBV_ILN_2055 GBV_ILN_2056 GBV_ILN_2059 GBV_ILN_2061 GBV_ILN_2064 GBV_ILN_2088 GBV_ILN_2106 GBV_ILN_2110 GBV_ILN_2112 GBV_ILN_2122 GBV_ILN_2129 GBV_ILN_2143 GBV_ILN_2152 GBV_ILN_2153 GBV_ILN_2190 GBV_ILN_2232 GBV_ILN_2336 GBV_ILN_2470 GBV_ILN_2507 GBV_ILN_4012 GBV_ILN_4035 GBV_ILN_4037 GBV_ILN_4112 GBV_ILN_4125 GBV_ILN_4126 GBV_ILN_4242 GBV_ILN_4249 GBV_ILN_4251 GBV_ILN_4305 GBV_ILN_4306 GBV_ILN_4307 GBV_ILN_4313 GBV_ILN_4322 GBV_ILN_4323 GBV_ILN_4324 GBV_ILN_4325 GBV_ILN_4326 GBV_ILN_4333 GBV_ILN_4334 GBV_ILN_4338 GBV_ILN_4367 GBV_ILN_4393 GBV_ILN_4700 AR 17 2024 13
allfieldsGer	10.1016/j.xjon.2023.11.007 doi (DE-627)DOAJ101352255 (DE-599)DOAJ0b89659f136949e0931ecde398152005 DE-627 ger DE-627 rakwb eng RC666-701 RD1-811 Syeda Manahil Haider Jeoffrey, MD verfasserin aut Midterm follow-up of composite graft replacement of the aortic root (30-year experience)—remarkably safe, effective, and durableCentral MessagePerspective 2024 Text txt rdacontent Computermedien c rdamedia Online-Ressource cr rdacarrier Objectives: Contemporary operative choices for aortic root disease include aortic root replacement (ARR) and a variety of valve-sparing and aortic root-repair procedures. We evaluate ultra-long-term outcomes of ARR, focusing on survival, freedom from late reoperation, and adverse events. Methods: Prospectively kept records were used to accomplish long-term follow-up of patients who underwent ARR (4-pronged Yale survival assessment paradigm). Results: Between 1990 and 2020, 564 patients underwent ARR (mean 56 years, 84% male). A modified Cabrol procedure (Dacron coronary graft) was employed in 9.0% (51/564) and concomitant coronary artery bypass grafting in 9.4% (53/564). There were 12.8% (72/564) urgent/emergent and 7.4% (42/564) redo procedures. Operative mortality occurred in 12 patients (2.1%) overall, or 1.4% (8/554) of nondissection and 1.3% (6/468) of elective first-time operations. Six of the 12 deaths presented with acute type A dissection, urgent operation, or reoperative states. Operative mortality dropped to 0.6% during the past 10 years. In total, 11 patients developed endocarditis. Stroke occurred in 11 of 564 patients (2.0%), 4 of whom had presented with type A dissection. Late events included bleeding in 2.8% (16/564), thromboembolism in 1.4% (8/564), and reoperation of the root in 5 of 564 (0.9%) at 15 years and more distal aortic segments in 16/564 (2.8%). Survival was no different from age/sex-matched controls. Conclusions: This ultra-long-term experience finds ARR to be extraordinarily safe, effective, and durable, with minimal long-term bleeding, thromboembolism, or graft failure. This experience provides a standard of durability for ARR against which ultra-long-term outcomes with alternate procedures (valve-sparing, Ross, other) may be compared. composite aortic graft Cabrol procedure aortic root repair valve sparing Dacron coronary graft aortic root replacement Diseases of the circulatory (Cardiovascular) system Surgery Mohammad A. Zafar, MBBS verfasserin aut Juan Velasco, MD verfasserin aut Ahad Khattak, MD verfasserin aut Hesham Ellauzi, MB BCh, BAO (hons) verfasserin aut Afsheen Nasir, MD verfasserin aut Asanish Kalyanasundaram, MD verfasserin aut Bulat A. Ziganshin, MD, PhD verfasserin aut John A. Elefteriades, MD, PhD (Hon) verfasserin aut In JTCVS Open Elsevier, 2022 17(2024), Seite 13 (DE-627)1702642518 26662736 nnns volume:17 year:2024 pages:13 https://doi.org/10.1016/j.xjon.2023.11.007 kostenfrei https://doaj.org/article/0b89659f136949e0931ecde398152005 kostenfrei http://www.sciencedirect.com/science/article/pii/S2666273623003601 kostenfrei https://doaj.org/toc/2666-2736 Journal toc kostenfrei GBV_USEFLAG_A SYSFLAG_A GBV_DOAJ GBV_ILN_20 GBV_ILN_22 GBV_ILN_23 GBV_ILN_24 GBV_ILN_31 GBV_ILN_39 GBV_ILN_40 GBV_ILN_60 GBV_ILN_62 GBV_ILN_63 GBV_ILN_65 GBV_ILN_69 GBV_ILN_73 GBV_ILN_74 GBV_ILN_95 GBV_ILN_105 GBV_ILN_110 GBV_ILN_151 GBV_ILN_161 GBV_ILN_170 GBV_ILN_206 GBV_ILN_213 GBV_ILN_224 GBV_ILN_230 GBV_ILN_285 GBV_ILN_293 GBV_ILN_602 GBV_ILN_2001 GBV_ILN_2003 GBV_ILN_2005 GBV_ILN_2006 GBV_ILN_2007 GBV_ILN_2008 GBV_ILN_2009 GBV_ILN_2010 GBV_ILN_2011 GBV_ILN_2014 GBV_ILN_2015 GBV_ILN_2020 GBV_ILN_2021 GBV_ILN_2025 GBV_ILN_2026 GBV_ILN_2027 GBV_ILN_2034 GBV_ILN_2038 GBV_ILN_2044 GBV_ILN_2048 GBV_ILN_2049 GBV_ILN_2050 GBV_ILN_2055 GBV_ILN_2056 GBV_ILN_2059 GBV_ILN_2061 GBV_ILN_2064 GBV_ILN_2088 GBV_ILN_2106 GBV_ILN_2110 GBV_ILN_2112 GBV_ILN_2122 GBV_ILN_2129 GBV_ILN_2143 GBV_ILN_2152 GBV_ILN_2153 GBV_ILN_2190 GBV_ILN_2232 GBV_ILN_2336 GBV_ILN_2470 GBV_ILN_2507 GBV_ILN_4012 GBV_ILN_4035 GBV_ILN_4037 GBV_ILN_4112 GBV_ILN_4125 GBV_ILN_4126 GBV_ILN_4242 GBV_ILN_4249 GBV_ILN_4251 GBV_ILN_4305 GBV_ILN_4306 GBV_ILN_4307 GBV_ILN_4313 GBV_ILN_4322 GBV_ILN_4323 GBV_ILN_4324 GBV_ILN_4325 GBV_ILN_4326 GBV_ILN_4333 GBV_ILN_4334 GBV_ILN_4338 GBV_ILN_4367 GBV_ILN_4393 GBV_ILN_4700 AR 17 2024 13
allfieldsSound	10.1016/j.xjon.2023.11.007 doi (DE-627)DOAJ101352255 (DE-599)DOAJ0b89659f136949e0931ecde398152005 DE-627 ger DE-627 rakwb eng RC666-701 RD1-811 Syeda Manahil Haider Jeoffrey, MD verfasserin aut Midterm follow-up of composite graft replacement of the aortic root (30-year experience)—remarkably safe, effective, and durableCentral MessagePerspective 2024 Text txt rdacontent Computermedien c rdamedia Online-Ressource cr rdacarrier Objectives: Contemporary operative choices for aortic root disease include aortic root replacement (ARR) and a variety of valve-sparing and aortic root-repair procedures. We evaluate ultra-long-term outcomes of ARR, focusing on survival, freedom from late reoperation, and adverse events. Methods: Prospectively kept records were used to accomplish long-term follow-up of patients who underwent ARR (4-pronged Yale survival assessment paradigm). Results: Between 1990 and 2020, 564 patients underwent ARR (mean 56 years, 84% male). A modified Cabrol procedure (Dacron coronary graft) was employed in 9.0% (51/564) and concomitant coronary artery bypass grafting in 9.4% (53/564). There were 12.8% (72/564) urgent/emergent and 7.4% (42/564) redo procedures. Operative mortality occurred in 12 patients (2.1%) overall, or 1.4% (8/554) of nondissection and 1.3% (6/468) of elective first-time operations. Six of the 12 deaths presented with acute type A dissection, urgent operation, or reoperative states. Operative mortality dropped to 0.6% during the past 10 years. In total, 11 patients developed endocarditis. Stroke occurred in 11 of 564 patients (2.0%), 4 of whom had presented with type A dissection. Late events included bleeding in 2.8% (16/564), thromboembolism in 1.4% (8/564), and reoperation of the root in 5 of 564 (0.9%) at 15 years and more distal aortic segments in 16/564 (2.8%). Survival was no different from age/sex-matched controls. Conclusions: This ultra-long-term experience finds ARR to be extraordinarily safe, effective, and durable, with minimal long-term bleeding, thromboembolism, or graft failure. This experience provides a standard of durability for ARR against which ultra-long-term outcomes with alternate procedures (valve-sparing, Ross, other) may be compared. composite aortic graft Cabrol procedure aortic root repair valve sparing Dacron coronary graft aortic root replacement Diseases of the circulatory (Cardiovascular) system Surgery Mohammad A. Zafar, MBBS verfasserin aut Juan Velasco, MD verfasserin aut Ahad Khattak, MD verfasserin aut Hesham Ellauzi, MB BCh, BAO (hons) verfasserin aut Afsheen Nasir, MD verfasserin aut Asanish Kalyanasundaram, MD verfasserin aut Bulat A. Ziganshin, MD, PhD verfasserin aut John A. Elefteriades, MD, PhD (Hon) verfasserin aut In JTCVS Open Elsevier, 2022 17(2024), Seite 13 (DE-627)1702642518 26662736 nnns volume:17 year:2024 pages:13 https://doi.org/10.1016/j.xjon.2023.11.007 kostenfrei https://doaj.org/article/0b89659f136949e0931ecde398152005 kostenfrei http://www.sciencedirect.com/science/article/pii/S2666273623003601 kostenfrei https://doaj.org/toc/2666-2736 Journal toc kostenfrei GBV_USEFLAG_A SYSFLAG_A GBV_DOAJ GBV_ILN_20 GBV_ILN_22 GBV_ILN_23 GBV_ILN_24 GBV_ILN_31 GBV_ILN_39 GBV_ILN_40 GBV_ILN_60 GBV_ILN_62 GBV_ILN_63 GBV_ILN_65 GBV_ILN_69 GBV_ILN_73 GBV_ILN_74 GBV_ILN_95 GBV_ILN_105 GBV_ILN_110 GBV_ILN_151 GBV_ILN_161 GBV_ILN_170 GBV_ILN_206 GBV_ILN_213 GBV_ILN_224 GBV_ILN_230 GBV_ILN_285 GBV_ILN_293 GBV_ILN_602 GBV_ILN_2001 GBV_ILN_2003 GBV_ILN_2005 GBV_ILN_2006 GBV_ILN_2007 GBV_ILN_2008 GBV_ILN_2009 GBV_ILN_2010 GBV_ILN_2011 GBV_ILN_2014 GBV_ILN_2015 GBV_ILN_2020 GBV_ILN_2021 GBV_ILN_2025 GBV_ILN_2026 GBV_ILN_2027 GBV_ILN_2034 GBV_ILN_2038 GBV_ILN_2044 GBV_ILN_2048 GBV_ILN_2049 GBV_ILN_2050 GBV_ILN_2055 GBV_ILN_2056 GBV_ILN_2059 GBV_ILN_2061 GBV_ILN_2064 GBV_ILN_2088 GBV_ILN_2106 GBV_ILN_2110 GBV_ILN_2112 GBV_ILN_2122 GBV_ILN_2129 GBV_ILN_2143 GBV_ILN_2152 GBV_ILN_2153 GBV_ILN_2190 GBV_ILN_2232 GBV_ILN_2336 GBV_ILN_2470 GBV_ILN_2507 GBV_ILN_4012 GBV_ILN_4035 GBV_ILN_4037 GBV_ILN_4112 GBV_ILN_4125 GBV_ILN_4126 GBV_ILN_4242 GBV_ILN_4249 GBV_ILN_4251 GBV_ILN_4305 GBV_ILN_4306 GBV_ILN_4307 GBV_ILN_4313 GBV_ILN_4322 GBV_ILN_4323 GBV_ILN_4324 GBV_ILN_4325 GBV_ILN_4326 GBV_ILN_4333 GBV_ILN_4334 GBV_ILN_4338 GBV_ILN_4367 GBV_ILN_4393 GBV_ILN_4700 AR 17 2024 13
language	English
source	In JTCVS Open 17(2024), Seite 13 volume:17 year:2024 pages:13
sourceStr	In JTCVS Open 17(2024), Seite 13 volume:17 year:2024 pages:13
format_phy_str_mv	Article
institution	findex.gbv.de
topic_facet	composite aortic graft Cabrol procedure aortic root repair valve sparing Dacron coronary graft aortic root replacement Diseases of the circulatory (Cardiovascular) system Surgery
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authorswithroles_txt_mv	Syeda Manahil Haider Jeoffrey, MD @@aut@@ Mohammad A. Zafar, MBBS @@aut@@ Juan Velasco, MD @@aut@@ Ahad Khattak, MD @@aut@@ Hesham Ellauzi, MB BCh, BAO (hons) @@aut@@ Afsheen Nasir, MD @@aut@@ Asanish Kalyanasundaram, MD @@aut@@ Bulat A. Ziganshin, MD, PhD @@aut@@ John A. Elefteriades, MD, PhD (Hon) @@aut@@
publishDateDaySort_date	2024-01-01T00:00:00Z
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We evaluate ultra-long-term outcomes of ARR, focusing on survival, freedom from late reoperation, and adverse events. Methods: Prospectively kept records were used to accomplish long-term follow-up of patients who underwent ARR (4-pronged Yale survival assessment paradigm). Results: Between 1990 and 2020, 564 patients underwent ARR (mean 56 years, 84% male). A modified Cabrol procedure (Dacron coronary graft) was employed in 9.0% (51/564) and concomitant coronary artery bypass grafting in 9.4% (53/564). There were 12.8% (72/564) urgent/emergent and 7.4% (42/564) redo procedures. Operative mortality occurred in 12 patients (2.1%) overall, or 1.4% (8/554) of nondissection and 1.3% (6/468) of elective first-time operations. Six of the 12 deaths presented with acute type A dissection, urgent operation, or reoperative states. Operative mortality dropped to 0.6% during the past 10 years. In total, 11 patients developed endocarditis. 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callnumber-first	R - Medicine
author	Syeda Manahil Haider Jeoffrey, MD
spellingShingle	Syeda Manahil Haider Jeoffrey, MD misc RC666-701 misc RD1-811 misc composite aortic graft misc Cabrol procedure misc aortic root repair misc valve sparing misc Dacron coronary graft misc aortic root replacement misc Diseases of the circulatory (Cardiovascular) system misc Surgery Midterm follow-up of composite graft replacement of the aortic root (30-year experience)—remarkably safe, effective, and durableCentral MessagePerspective
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topic_title	RC666-701 RD1-811 Midterm follow-up of composite graft replacement of the aortic root (30-year experience)—remarkably safe, effective, and durableCentral MessagePerspective composite aortic graft Cabrol procedure aortic root repair valve sparing Dacron coronary graft aortic root replacement
topic	misc RC666-701 misc RD1-811 misc composite aortic graft misc Cabrol procedure misc aortic root repair misc valve sparing misc Dacron coronary graft misc aortic root replacement misc Diseases of the circulatory (Cardiovascular) system misc Surgery
topic_unstemmed	misc RC666-701 misc RD1-811 misc composite aortic graft misc Cabrol procedure misc aortic root repair misc valve sparing misc Dacron coronary graft misc aortic root replacement misc Diseases of the circulatory (Cardiovascular) system misc Surgery
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title	Midterm follow-up of composite graft replacement of the aortic root (30-year experience)—remarkably safe, effective, and durableCentral MessagePerspective
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title_full	Midterm follow-up of composite graft replacement of the aortic root (30-year experience)—remarkably safe, effective, and durableCentral MessagePerspective
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author_browse	Syeda Manahil Haider Jeoffrey, MD Mohammad A. Zafar, MBBS Juan Velasco, MD Ahad Khattak, MD Hesham Ellauzi, MB BCh, BAO (hons) Afsheen Nasir, MD Asanish Kalyanasundaram, MD Bulat A. Ziganshin, MD, PhD John A. Elefteriades, MD, PhD (Hon)
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author-letter	Syeda Manahil Haider Jeoffrey, MD
doi_str_mv	10.1016/j.xjon.2023.11.007
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title_sort	midterm follow-up of composite graft replacement of the aortic root (30-year experience)—remarkably safe, effective, and durablecentral messageperspective
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title_auth	Midterm follow-up of composite graft replacement of the aortic root (30-year experience)—remarkably safe, effective, and durableCentral MessagePerspective
abstract	Objectives: Contemporary operative choices for aortic root disease include aortic root replacement (ARR) and a variety of valve-sparing and aortic root-repair procedures. We evaluate ultra-long-term outcomes of ARR, focusing on survival, freedom from late reoperation, and adverse events. Methods: Prospectively kept records were used to accomplish long-term follow-up of patients who underwent ARR (4-pronged Yale survival assessment paradigm). Results: Between 1990 and 2020, 564 patients underwent ARR (mean 56 years, 84% male). A modified Cabrol procedure (Dacron coronary graft) was employed in 9.0% (51/564) and concomitant coronary artery bypass grafting in 9.4% (53/564). There were 12.8% (72/564) urgent/emergent and 7.4% (42/564) redo procedures. Operative mortality occurred in 12 patients (2.1%) overall, or 1.4% (8/554) of nondissection and 1.3% (6/468) of elective first-time operations. Six of the 12 deaths presented with acute type A dissection, urgent operation, or reoperative states. Operative mortality dropped to 0.6% during the past 10 years. In total, 11 patients developed endocarditis. Stroke occurred in 11 of 564 patients (2.0%), 4 of whom had presented with type A dissection. Late events included bleeding in 2.8% (16/564), thromboembolism in 1.4% (8/564), and reoperation of the root in 5 of 564 (0.9%) at 15 years and more distal aortic segments in 16/564 (2.8%). Survival was no different from age/sex-matched controls. Conclusions: This ultra-long-term experience finds ARR to be extraordinarily safe, effective, and durable, with minimal long-term bleeding, thromboembolism, or graft failure. This experience provides a standard of durability for ARR against which ultra-long-term outcomes with alternate procedures (valve-sparing, Ross, other) may be compared.
abstractGer	Objectives: Contemporary operative choices for aortic root disease include aortic root replacement (ARR) and a variety of valve-sparing and aortic root-repair procedures. We evaluate ultra-long-term outcomes of ARR, focusing on survival, freedom from late reoperation, and adverse events. Methods: Prospectively kept records were used to accomplish long-term follow-up of patients who underwent ARR (4-pronged Yale survival assessment paradigm). Results: Between 1990 and 2020, 564 patients underwent ARR (mean 56 years, 84% male). A modified Cabrol procedure (Dacron coronary graft) was employed in 9.0% (51/564) and concomitant coronary artery bypass grafting in 9.4% (53/564). There were 12.8% (72/564) urgent/emergent and 7.4% (42/564) redo procedures. Operative mortality occurred in 12 patients (2.1%) overall, or 1.4% (8/554) of nondissection and 1.3% (6/468) of elective first-time operations. Six of the 12 deaths presented with acute type A dissection, urgent operation, or reoperative states. Operative mortality dropped to 0.6% during the past 10 years. In total, 11 patients developed endocarditis. Stroke occurred in 11 of 564 patients (2.0%), 4 of whom had presented with type A dissection. Late events included bleeding in 2.8% (16/564), thromboembolism in 1.4% (8/564), and reoperation of the root in 5 of 564 (0.9%) at 15 years and more distal aortic segments in 16/564 (2.8%). Survival was no different from age/sex-matched controls. Conclusions: This ultra-long-term experience finds ARR to be extraordinarily safe, effective, and durable, with minimal long-term bleeding, thromboembolism, or graft failure. This experience provides a standard of durability for ARR against which ultra-long-term outcomes with alternate procedures (valve-sparing, Ross, other) may be compared.
abstract_unstemmed	Objectives: Contemporary operative choices for aortic root disease include aortic root replacement (ARR) and a variety of valve-sparing and aortic root-repair procedures. We evaluate ultra-long-term outcomes of ARR, focusing on survival, freedom from late reoperation, and adverse events. Methods: Prospectively kept records were used to accomplish long-term follow-up of patients who underwent ARR (4-pronged Yale survival assessment paradigm). Results: Between 1990 and 2020, 564 patients underwent ARR (mean 56 years, 84% male). A modified Cabrol procedure (Dacron coronary graft) was employed in 9.0% (51/564) and concomitant coronary artery bypass grafting in 9.4% (53/564). There were 12.8% (72/564) urgent/emergent and 7.4% (42/564) redo procedures. Operative mortality occurred in 12 patients (2.1%) overall, or 1.4% (8/554) of nondissection and 1.3% (6/468) of elective first-time operations. Six of the 12 deaths presented with acute type A dissection, urgent operation, or reoperative states. Operative mortality dropped to 0.6% during the past 10 years. In total, 11 patients developed endocarditis. Stroke occurred in 11 of 564 patients (2.0%), 4 of whom had presented with type A dissection. Late events included bleeding in 2.8% (16/564), thromboembolism in 1.4% (8/564), and reoperation of the root in 5 of 564 (0.9%) at 15 years and more distal aortic segments in 16/564 (2.8%). Survival was no different from age/sex-matched controls. Conclusions: This ultra-long-term experience finds ARR to be extraordinarily safe, effective, and durable, with minimal long-term bleeding, thromboembolism, or graft failure. This experience provides a standard of durability for ARR against which ultra-long-term outcomes with alternate procedures (valve-sparing, Ross, other) may be compared.
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title_short	Midterm follow-up of composite graft replacement of the aortic root (30-year experience)—remarkably safe, effective, and durableCentral MessagePerspective
url	https://doi.org/10.1016/j.xjon.2023.11.007 https://doaj.org/article/0b89659f136949e0931ecde398152005 http://www.sciencedirect.com/science/article/pii/S2666273623003601 https://doaj.org/toc/2666-2736
remote_bool	true
author2	Mohammad A. Zafar, MBBS Juan Velasco, MD Ahad Khattak, MD Hesham Ellauzi, MB BCh, BAO (hons) Afsheen Nasir, MD Asanish Kalyanasundaram, MD Bulat A. Ziganshin, MD, PhD John A. Elefteriades, MD, PhD (Hon)
author2Str	Mohammad A. Zafar, MBBS Juan Velasco, MD Ahad Khattak, MD Hesham Ellauzi, MB BCh, BAO (hons) Afsheen Nasir, MD Asanish Kalyanasundaram, MD Bulat A. Ziganshin, MD, PhD John A. Elefteriades, MD, PhD (Hon)
ppnlink	1702642518
callnumber-subject	RC - Internal Medicine
mediatype_str_mv	c
isOA_txt	true
hochschulschrift_bool	false
doi_str	10.1016/j.xjon.2023.11.007
callnumber-a	RC666-701
up_date	2024-07-03T20:09:12.438Z
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Midterm follow-up of composite graft replacement of the aortic root (30-year experience)—remarkably safe, effective, and durableCentral MessagePerspective

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