A Phase I trial to evaluate the safety and immunogenicity of WRSs2 and WRSs3; two live oral candidate vaccines against

Effective vaccines are needed to combat diarrheal diseases due to Shigella. Two live oral S. sonnei vaccine candidates, WRSs2 and WRSs3, attenuated principally by the lack of spreading ability, as well as the loss of enterotoxin and acyl transferase genes, were tested for safety and immunogenicity.

Gespeichert in:
Autor*in:

Frenck, Robert W [verfasserIn]

Baqar, Shahida [verfasserIn]

Alexander, William [verfasserIn]

Dickey, Michelle [verfasserIn]

McNeal, Monica [verfasserIn]

El-Khorazaty, Jill [verfasserIn]

Baughman, Holly [verfasserIn]

Hoeper, Amy [verfasserIn]

Barnoy, Shoshana [verfasserIn]

Suvarnapunya, Akamol E. [verfasserIn]

Kaminski, Robert W. [verfasserIn]

Venkatesan, Malabi M. [verfasserIn]

Format:

E-Artikel

Sprache:

Englisch

Erschienen:

2018

Schlagwörter:

Phase I study

Live vaccines

WRSs2/3

Übergeordnetes Werk:

Enthalten in: Vaccine - Amsterdam : Elsevier, 1983, 36, Seite 4880-4889

Übergeordnetes Werk:

volume:36 ; pages:4880-4889

DOI / URN:

10.1016/j.vaccine.2018.06.063

Katalog-ID:

ELV000090522

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