A Phase I trial to evaluate the safety and immunogenicity of WRSs2 and WRSs3; two live oral candidate vaccines against
Effective vaccines are needed to combat diarrheal diseases due to Shigella. Two live oral S. sonnei vaccine candidates, WRSs2 and WRSs3, attenuated principally by the lack of spreading ability, as well as the loss of enterotoxin and acyl transferase genes, were tested for safety and immunogenicity.
Gespeichert in:
| Autor*in: |
Frenck, Robert W [verfasserIn] Baqar, Shahida [verfasserIn] Alexander, William [verfasserIn] Dickey, Michelle [verfasserIn] McNeal, Monica [verfasserIn] El-Khorazaty, Jill [verfasserIn] Baughman, Holly [verfasserIn] Hoeper, Amy [verfasserIn] Barnoy, Shoshana [verfasserIn] Suvarnapunya, Akamol E. [verfasserIn] Kaminski, Robert W. [verfasserIn] Venkatesan, Malabi M. [verfasserIn] |
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| Format: |
E-Artikel |
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| Sprache: |
Englisch |
| Erschienen: |
2018 |
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| Schlagwörter: |
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| Übergeordnetes Werk: |
Enthalten in: Vaccine - Amsterdam : Elsevier, 1983, 36, Seite 4880-4889 |
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| Übergeordnetes Werk: |
volume:36 ; pages:4880-4889 |
| DOI / URN: |
10.1016/j.vaccine.2018.06.063 |
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| 245 | 1 | 0 | |a A Phase I trial to evaluate the safety and immunogenicity of WRSs2 and WRSs3; two live oral candidate vaccines against |
| 264 | 1 | |c 2018 | |
| 336 | |a nicht spezifiziert |b zzz |2 rdacontent | ||
| 337 | |a Computermedien |b c |2 rdamedia | ||
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| 520 | |a Effective vaccines are needed to combat diarrheal diseases due to Shigella. Two live oral S. sonnei vaccine candidates, WRSs2 and WRSs3, attenuated principally by the lack of spreading ability, as well as the loss of enterotoxin and acyl transferase genes, were tested for safety and immunogenicity. | ||
| 650 | 4 | |a Phase I study | |
| 650 | 4 | |a Live vaccines | |
| 650 | 4 | |a WRSs2/3 | |
| 700 | 1 | |a Baqar, Shahida |e verfasserin |4 aut | |
| 700 | 1 | |a Alexander, William |e verfasserin |4 aut | |
| 700 | 1 | |a Dickey, Michelle |e verfasserin |4 aut | |
| 700 | 1 | |a McNeal, Monica |e verfasserin |4 aut | |
| 700 | 1 | |a El-Khorazaty, Jill |e verfasserin |4 aut | |
| 700 | 1 | |a Baughman, Holly |e verfasserin |4 aut | |
| 700 | 1 | |a Hoeper, Amy |e verfasserin |4 aut | |
| 700 | 1 | |a Barnoy, Shoshana |e verfasserin |4 aut | |
| 700 | 1 | |a Suvarnapunya, Akamol E. |e verfasserin |4 aut | |
| 700 | 1 | |a Kaminski, Robert W. |e verfasserin |4 aut | |
| 700 | 1 | |a Venkatesan, Malabi M. |e verfasserin |4 aut | |
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10.1016/j.vaccine.2018.06.063 doi (DE-627)ELV000090522 (ELSEVIER)S0264-410X(18)30904-6 DE-627 ger DE-627 rda eng 610 DE-600 44.45 bkl Frenck, Robert W verfasserin aut A Phase I trial to evaluate the safety and immunogenicity of WRSs2 and WRSs3; two live oral candidate vaccines against 2018 nicht spezifiziert zzz rdacontent Computermedien c rdamedia Online-Ressource cr rdacarrier Effective vaccines are needed to combat diarrheal diseases due to Shigella. Two live oral S. sonnei vaccine candidates, WRSs2 and WRSs3, attenuated principally by the lack of spreading ability, as well as the loss of enterotoxin and acyl transferase genes, were tested for safety and immunogenicity. Phase I study Live vaccines WRSs2/3 Baqar, Shahida verfasserin aut Alexander, William verfasserin aut Dickey, Michelle verfasserin aut McNeal, Monica verfasserin aut El-Khorazaty, Jill verfasserin aut Baughman, Holly verfasserin aut Hoeper, Amy verfasserin aut Barnoy, Shoshana verfasserin aut Suvarnapunya, Akamol E. verfasserin aut Kaminski, Robert W. verfasserin aut Venkatesan, Malabi M. verfasserin aut Enthalten in Vaccine Amsterdam : Elsevier, 1983 36, Seite 4880-4889 Online-Ressource (DE-627)266886078 (DE-600)1468474-3 (DE-576)075961857 1873-2518 nnns volume:36 pages:4880-4889 GBV_USEFLAG_U SYSFLAG_U GBV_ELV GBV_ILN_20 GBV_ILN_22 GBV_ILN_23 GBV_ILN_24 GBV_ILN_31 GBV_ILN_32 GBV_ILN_40 GBV_ILN_60 GBV_ILN_62 GBV_ILN_63 GBV_ILN_65 GBV_ILN_69 GBV_ILN_70 GBV_ILN_73 GBV_ILN_74 GBV_ILN_90 GBV_ILN_95 GBV_ILN_100 GBV_ILN_101 GBV_ILN_105 GBV_ILN_110 GBV_ILN_151 GBV_ILN_224 GBV_ILN_252 GBV_ILN_370 GBV_ILN_602 GBV_ILN_702 GBV_ILN_2003 GBV_ILN_2004 GBV_ILN_2005 GBV_ILN_2011 GBV_ILN_2014 GBV_ILN_2015 GBV_ILN_2020 GBV_ILN_2021 GBV_ILN_2025 GBV_ILN_2027 GBV_ILN_2034 GBV_ILN_2038 GBV_ILN_2044 GBV_ILN_2048 GBV_ILN_2049 GBV_ILN_2050 GBV_ILN_2056 GBV_ILN_2059 GBV_ILN_2061 GBV_ILN_2064 GBV_ILN_2065 GBV_ILN_2068 GBV_ILN_2111 GBV_ILN_2112 GBV_ILN_2113 GBV_ILN_2118 GBV_ILN_2122 GBV_ILN_2129 GBV_ILN_2143 GBV_ILN_2147 GBV_ILN_2148 GBV_ILN_2152 GBV_ILN_2153 GBV_ILN_2190 GBV_ILN_2336 GBV_ILN_2507 GBV_ILN_2522 GBV_ILN_4035 GBV_ILN_4037 GBV_ILN_4112 GBV_ILN_4125 GBV_ILN_4126 GBV_ILN_4242 GBV_ILN_4251 GBV_ILN_4305 GBV_ILN_4313 GBV_ILN_4323 GBV_ILN_4324 GBV_ILN_4325 GBV_ILN_4326 GBV_ILN_4333 GBV_ILN_4334 GBV_ILN_4335 GBV_ILN_4338 GBV_ILN_4393 44.45 Immunologie AR 36 4880-4889 |
| spelling |
10.1016/j.vaccine.2018.06.063 doi (DE-627)ELV000090522 (ELSEVIER)S0264-410X(18)30904-6 DE-627 ger DE-627 rda eng 610 DE-600 44.45 bkl Frenck, Robert W verfasserin aut A Phase I trial to evaluate the safety and immunogenicity of WRSs2 and WRSs3; two live oral candidate vaccines against 2018 nicht spezifiziert zzz rdacontent Computermedien c rdamedia Online-Ressource cr rdacarrier Effective vaccines are needed to combat diarrheal diseases due to Shigella. Two live oral S. sonnei vaccine candidates, WRSs2 and WRSs3, attenuated principally by the lack of spreading ability, as well as the loss of enterotoxin and acyl transferase genes, were tested for safety and immunogenicity. Phase I study Live vaccines WRSs2/3 Baqar, Shahida verfasserin aut Alexander, William verfasserin aut Dickey, Michelle verfasserin aut McNeal, Monica verfasserin aut El-Khorazaty, Jill verfasserin aut Baughman, Holly verfasserin aut Hoeper, Amy verfasserin aut Barnoy, Shoshana verfasserin aut Suvarnapunya, Akamol E. verfasserin aut Kaminski, Robert W. verfasserin aut Venkatesan, Malabi M. verfasserin aut Enthalten in Vaccine Amsterdam : Elsevier, 1983 36, Seite 4880-4889 Online-Ressource (DE-627)266886078 (DE-600)1468474-3 (DE-576)075961857 1873-2518 nnns volume:36 pages:4880-4889 GBV_USEFLAG_U SYSFLAG_U GBV_ELV GBV_ILN_20 GBV_ILN_22 GBV_ILN_23 GBV_ILN_24 GBV_ILN_31 GBV_ILN_32 GBV_ILN_40 GBV_ILN_60 GBV_ILN_62 GBV_ILN_63 GBV_ILN_65 GBV_ILN_69 GBV_ILN_70 GBV_ILN_73 GBV_ILN_74 GBV_ILN_90 GBV_ILN_95 GBV_ILN_100 GBV_ILN_101 GBV_ILN_105 GBV_ILN_110 GBV_ILN_151 GBV_ILN_224 GBV_ILN_252 GBV_ILN_370 GBV_ILN_602 GBV_ILN_702 GBV_ILN_2003 GBV_ILN_2004 GBV_ILN_2005 GBV_ILN_2011 GBV_ILN_2014 GBV_ILN_2015 GBV_ILN_2020 GBV_ILN_2021 GBV_ILN_2025 GBV_ILN_2027 GBV_ILN_2034 GBV_ILN_2038 GBV_ILN_2044 GBV_ILN_2048 GBV_ILN_2049 GBV_ILN_2050 GBV_ILN_2056 GBV_ILN_2059 GBV_ILN_2061 GBV_ILN_2064 GBV_ILN_2065 GBV_ILN_2068 GBV_ILN_2111 GBV_ILN_2112 GBV_ILN_2113 GBV_ILN_2118 GBV_ILN_2122 GBV_ILN_2129 GBV_ILN_2143 GBV_ILN_2147 GBV_ILN_2148 GBV_ILN_2152 GBV_ILN_2153 GBV_ILN_2190 GBV_ILN_2336 GBV_ILN_2507 GBV_ILN_2522 GBV_ILN_4035 GBV_ILN_4037 GBV_ILN_4112 GBV_ILN_4125 GBV_ILN_4126 GBV_ILN_4242 GBV_ILN_4251 GBV_ILN_4305 GBV_ILN_4313 GBV_ILN_4323 GBV_ILN_4324 GBV_ILN_4325 GBV_ILN_4326 GBV_ILN_4333 GBV_ILN_4334 GBV_ILN_4335 GBV_ILN_4338 GBV_ILN_4393 44.45 Immunologie AR 36 4880-4889 |
| allfields_unstemmed |
10.1016/j.vaccine.2018.06.063 doi (DE-627)ELV000090522 (ELSEVIER)S0264-410X(18)30904-6 DE-627 ger DE-627 rda eng 610 DE-600 44.45 bkl Frenck, Robert W verfasserin aut A Phase I trial to evaluate the safety and immunogenicity of WRSs2 and WRSs3; two live oral candidate vaccines against 2018 nicht spezifiziert zzz rdacontent Computermedien c rdamedia Online-Ressource cr rdacarrier Effective vaccines are needed to combat diarrheal diseases due to Shigella. Two live oral S. sonnei vaccine candidates, WRSs2 and WRSs3, attenuated principally by the lack of spreading ability, as well as the loss of enterotoxin and acyl transferase genes, were tested for safety and immunogenicity. Phase I study Live vaccines WRSs2/3 Baqar, Shahida verfasserin aut Alexander, William verfasserin aut Dickey, Michelle verfasserin aut McNeal, Monica verfasserin aut El-Khorazaty, Jill verfasserin aut Baughman, Holly verfasserin aut Hoeper, Amy verfasserin aut Barnoy, Shoshana verfasserin aut Suvarnapunya, Akamol E. verfasserin aut Kaminski, Robert W. verfasserin aut Venkatesan, Malabi M. verfasserin aut Enthalten in Vaccine Amsterdam : Elsevier, 1983 36, Seite 4880-4889 Online-Ressource (DE-627)266886078 (DE-600)1468474-3 (DE-576)075961857 1873-2518 nnns volume:36 pages:4880-4889 GBV_USEFLAG_U SYSFLAG_U GBV_ELV GBV_ILN_20 GBV_ILN_22 GBV_ILN_23 GBV_ILN_24 GBV_ILN_31 GBV_ILN_32 GBV_ILN_40 GBV_ILN_60 GBV_ILN_62 GBV_ILN_63 GBV_ILN_65 GBV_ILN_69 GBV_ILN_70 GBV_ILN_73 GBV_ILN_74 GBV_ILN_90 GBV_ILN_95 GBV_ILN_100 GBV_ILN_101 GBV_ILN_105 GBV_ILN_110 GBV_ILN_151 GBV_ILN_224 GBV_ILN_252 GBV_ILN_370 GBV_ILN_602 GBV_ILN_702 GBV_ILN_2003 GBV_ILN_2004 GBV_ILN_2005 GBV_ILN_2011 GBV_ILN_2014 GBV_ILN_2015 GBV_ILN_2020 GBV_ILN_2021 GBV_ILN_2025 GBV_ILN_2027 GBV_ILN_2034 GBV_ILN_2038 GBV_ILN_2044 GBV_ILN_2048 GBV_ILN_2049 GBV_ILN_2050 GBV_ILN_2056 GBV_ILN_2059 GBV_ILN_2061 GBV_ILN_2064 GBV_ILN_2065 GBV_ILN_2068 GBV_ILN_2111 GBV_ILN_2112 GBV_ILN_2113 GBV_ILN_2118 GBV_ILN_2122 GBV_ILN_2129 GBV_ILN_2143 GBV_ILN_2147 GBV_ILN_2148 GBV_ILN_2152 GBV_ILN_2153 GBV_ILN_2190 GBV_ILN_2336 GBV_ILN_2507 GBV_ILN_2522 GBV_ILN_4035 GBV_ILN_4037 GBV_ILN_4112 GBV_ILN_4125 GBV_ILN_4126 GBV_ILN_4242 GBV_ILN_4251 GBV_ILN_4305 GBV_ILN_4313 GBV_ILN_4323 GBV_ILN_4324 GBV_ILN_4325 GBV_ILN_4326 GBV_ILN_4333 GBV_ILN_4334 GBV_ILN_4335 GBV_ILN_4338 GBV_ILN_4393 44.45 Immunologie AR 36 4880-4889 |
| allfieldsGer |
10.1016/j.vaccine.2018.06.063 doi (DE-627)ELV000090522 (ELSEVIER)S0264-410X(18)30904-6 DE-627 ger DE-627 rda eng 610 DE-600 44.45 bkl Frenck, Robert W verfasserin aut A Phase I trial to evaluate the safety and immunogenicity of WRSs2 and WRSs3; two live oral candidate vaccines against 2018 nicht spezifiziert zzz rdacontent Computermedien c rdamedia Online-Ressource cr rdacarrier Effective vaccines are needed to combat diarrheal diseases due to Shigella. Two live oral S. sonnei vaccine candidates, WRSs2 and WRSs3, attenuated principally by the lack of spreading ability, as well as the loss of enterotoxin and acyl transferase genes, were tested for safety and immunogenicity. Phase I study Live vaccines WRSs2/3 Baqar, Shahida verfasserin aut Alexander, William verfasserin aut Dickey, Michelle verfasserin aut McNeal, Monica verfasserin aut El-Khorazaty, Jill verfasserin aut Baughman, Holly verfasserin aut Hoeper, Amy verfasserin aut Barnoy, Shoshana verfasserin aut Suvarnapunya, Akamol E. verfasserin aut Kaminski, Robert W. verfasserin aut Venkatesan, Malabi M. verfasserin aut Enthalten in Vaccine Amsterdam : Elsevier, 1983 36, Seite 4880-4889 Online-Ressource (DE-627)266886078 (DE-600)1468474-3 (DE-576)075961857 1873-2518 nnns volume:36 pages:4880-4889 GBV_USEFLAG_U SYSFLAG_U GBV_ELV GBV_ILN_20 GBV_ILN_22 GBV_ILN_23 GBV_ILN_24 GBV_ILN_31 GBV_ILN_32 GBV_ILN_40 GBV_ILN_60 GBV_ILN_62 GBV_ILN_63 GBV_ILN_65 GBV_ILN_69 GBV_ILN_70 GBV_ILN_73 GBV_ILN_74 GBV_ILN_90 GBV_ILN_95 GBV_ILN_100 GBV_ILN_101 GBV_ILN_105 GBV_ILN_110 GBV_ILN_151 GBV_ILN_224 GBV_ILN_252 GBV_ILN_370 GBV_ILN_602 GBV_ILN_702 GBV_ILN_2003 GBV_ILN_2004 GBV_ILN_2005 GBV_ILN_2011 GBV_ILN_2014 GBV_ILN_2015 GBV_ILN_2020 GBV_ILN_2021 GBV_ILN_2025 GBV_ILN_2027 GBV_ILN_2034 GBV_ILN_2038 GBV_ILN_2044 GBV_ILN_2048 GBV_ILN_2049 GBV_ILN_2050 GBV_ILN_2056 GBV_ILN_2059 GBV_ILN_2061 GBV_ILN_2064 GBV_ILN_2065 GBV_ILN_2068 GBV_ILN_2111 GBV_ILN_2112 GBV_ILN_2113 GBV_ILN_2118 GBV_ILN_2122 GBV_ILN_2129 GBV_ILN_2143 GBV_ILN_2147 GBV_ILN_2148 GBV_ILN_2152 GBV_ILN_2153 GBV_ILN_2190 GBV_ILN_2336 GBV_ILN_2507 GBV_ILN_2522 GBV_ILN_4035 GBV_ILN_4037 GBV_ILN_4112 GBV_ILN_4125 GBV_ILN_4126 GBV_ILN_4242 GBV_ILN_4251 GBV_ILN_4305 GBV_ILN_4313 GBV_ILN_4323 GBV_ILN_4324 GBV_ILN_4325 GBV_ILN_4326 GBV_ILN_4333 GBV_ILN_4334 GBV_ILN_4335 GBV_ILN_4338 GBV_ILN_4393 44.45 Immunologie AR 36 4880-4889 |
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A Phase I trial to evaluate the safety and immunogenicity of WRSs2 and WRSs3; two live oral candidate vaccines against |
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A Phase I trial to evaluate the safety and immunogenicity of WRSs2 and WRSs3; two live oral candidate vaccines against |
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Frenck, Robert W |
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Vaccine |
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eng |
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Frenck, Robert W Baqar, Shahida Alexander, William Dickey, Michelle McNeal, Monica El-Khorazaty, Jill Baughman, Holly Hoeper, Amy Barnoy, Shoshana Suvarnapunya, Akamol E. Kaminski, Robert W. Venkatesan, Malabi M. |
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Elektronische Aufsätze |
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Frenck, Robert W |
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10.1016/j.vaccine.2018.06.063 |
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610 |
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verfasserin |
| title_sort |
a phase i trial to evaluate the safety and immunogenicity of wrss2 and wrss3; two live oral candidate vaccines against |
| title_auth |
A Phase I trial to evaluate the safety and immunogenicity of WRSs2 and WRSs3; two live oral candidate vaccines against |
| abstract |
Effective vaccines are needed to combat diarrheal diseases due to Shigella. Two live oral S. sonnei vaccine candidates, WRSs2 and WRSs3, attenuated principally by the lack of spreading ability, as well as the loss of enterotoxin and acyl transferase genes, were tested for safety and immunogenicity. |
| abstractGer |
Effective vaccines are needed to combat diarrheal diseases due to Shigella. Two live oral S. sonnei vaccine candidates, WRSs2 and WRSs3, attenuated principally by the lack of spreading ability, as well as the loss of enterotoxin and acyl transferase genes, were tested for safety and immunogenicity. |
| abstract_unstemmed |
Effective vaccines are needed to combat diarrheal diseases due to Shigella. Two live oral S. sonnei vaccine candidates, WRSs2 and WRSs3, attenuated principally by the lack of spreading ability, as well as the loss of enterotoxin and acyl transferase genes, were tested for safety and immunogenicity. |
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| title_short |
A Phase I trial to evaluate the safety and immunogenicity of WRSs2 and WRSs3; two live oral candidate vaccines against |
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Baqar, Shahida Alexander, William Dickey, Michelle McNeal, Monica El-Khorazaty, Jill Baughman, Holly Hoeper, Amy Barnoy, Shoshana Suvarnapunya, Akamol E. Kaminski, Robert W. Venkatesan, Malabi M. |
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Baqar, Shahida Alexander, William Dickey, Michelle McNeal, Monica El-Khorazaty, Jill Baughman, Holly Hoeper, Amy Barnoy, Shoshana Suvarnapunya, Akamol E. Kaminski, Robert W. Venkatesan, Malabi M. |
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2024-07-06T16:49:54.868Z |
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