Risk factors for hepatic insufficiency after major hepatectomy in non-cirrhotic patients

Background: Although recent advances in surgical techniques and perioperative management have reduced the morbidity and mortality after hepatectomy, hepatic insufficiency after major hepatectomy remains an important concern. This study aimed to clarify the risk factors for post-hepatectomy liver ins...
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Autor*in:	Fujii, Yoshiro [verfasserIn] Nanashima, Atsushi [verfasserIn] Hiyoshi, Masahide [verfasserIn] Imamura, Naoya [verfasserIn] Yano, Koichi [verfasserIn] Hamada, Takeomi [verfasserIn]

Format:	E-Artikel
Sprache:	Englisch

Erschienen:	2018

Schlagwörter:	Risk factor Hepatic insufficiency Major hepatectomy

Übergeordnetes Werk:	Enthalten in: Asian journal of surgery - Hong Kong : Excerpta Medica Asia, 2000, 42, Seite 251-255
Übergeordnetes Werk:	volume:42 ; pages:251-255

DOI / URN:	10.1016/j.asjsur.2018.03.002

Katalog-ID:	ELV001290479

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520			\|a Background: Although recent advances in surgical techniques and perioperative management have reduced the morbidity and mortality after hepatectomy, hepatic insufficiency after major hepatectomy remains an important concern. This study aimed to clarify the risk factors for post-hepatectomy liver insufficiency.Methods: We enrolled 103 consecutive patients who underwent major hepatectomy which was defined as resection of four or more segments. Hepatic insufficiency is defined as an increase in serum total bilirubin after hepatectomy of 7 mg/dL or more, or death from multiple organ failure. We compared the patient disposition, demographics, perioperative factors such as surgical method, combined procedure, morbidity and so on between the patients with or without hepatic insufficiency.Results: Hepatic insufficiency occurred in 14 patients (14%) and six of them died during the hospital stay (6%). Risk factors by univariate analysis were the percentage of hepatic parenchyma to be resected (P = .025), combined procedure (P = .008) and postoperative morbidity excluding hepatic insufficiency (P < .001). A combined procedure (P = .036) and postoperative morbidity excluding hepatic insufficiency (P = .002) were a significant risk factor by multivariate analysis.Conclusion: Unless remaining liver after hepatectomy has enough volume, combined procedure may account for hepatic insufficiency, which can follow the development of postoperative morbidity.
650		4	\|a Risk factor
650		4	\|a Hepatic insufficiency
650		4	\|a Major hepatectomy
700	1		\|a Nanashima, Atsushi \|e verfasserin \|4 aut
700	1		\|a Hiyoshi, Masahide \|e verfasserin \|0 (orcid)0000-0002-2392-7787 \|4 aut
700	1		\|a Imamura, Naoya \|e verfasserin \|4 aut
700	1		\|a Yano, Koichi \|e verfasserin \|4 aut
700	1		\|a Hamada, Takeomi \|e verfasserin \|4 aut
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936	b	k	\|a 44.65 \|j Chirurgie
951			\|a AR
952			\|d 42 \|h 251-255

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allfields	10.1016/j.asjsur.2018.03.002 doi (DE-627)ELV001290479 (ELSEVIER)S1015-9584(17)30660-7 DE-627 ger DE-627 rda eng 610 DE-101 610 DE-600 44.65 bkl Fujii, Yoshiro verfasserin aut Risk factors for hepatic insufficiency after major hepatectomy in non-cirrhotic patients 2018 nicht spezifiziert zzz rdacontent Computermedien c rdamedia Online-Ressource cr rdacarrier Background: Although recent advances in surgical techniques and perioperative management have reduced the morbidity and mortality after hepatectomy, hepatic insufficiency after major hepatectomy remains an important concern. This study aimed to clarify the risk factors for post-hepatectomy liver insufficiency.Methods: We enrolled 103 consecutive patients who underwent major hepatectomy which was defined as resection of four or more segments. Hepatic insufficiency is defined as an increase in serum total bilirubin after hepatectomy of 7 mg/dL or more, or death from multiple organ failure. We compared the patient disposition, demographics, perioperative factors such as surgical method, combined procedure, morbidity and so on between the patients with or without hepatic insufficiency.Results: Hepatic insufficiency occurred in 14 patients (14%) and six of them died during the hospital stay (6%). Risk factors by univariate analysis were the percentage of hepatic parenchyma to be resected (P = .025), combined procedure (P = .008) and postoperative morbidity excluding hepatic insufficiency (P < .001). A combined procedure (P = .036) and postoperative morbidity excluding hepatic insufficiency (P = .002) were a significant risk factor by multivariate analysis.Conclusion: Unless remaining liver after hepatectomy has enough volume, combined procedure may account for hepatic insufficiency, which can follow the development of postoperative morbidity. Risk factor Hepatic insufficiency Major hepatectomy Nanashima, Atsushi verfasserin aut Hiyoshi, Masahide verfasserin (orcid)0000-0002-2392-7787 aut Imamura, Naoya verfasserin aut Yano, Koichi verfasserin aut Hamada, Takeomi verfasserin aut Enthalten in Asian journal of surgery Hong Kong : Excerpta Medica Asia, 2000 42, Seite 251-255 Online-Ressource (DE-627)324827164 (DE-600)2031317-2 (DE-576)272711896 0219-3108 nnns volume:42 pages:251-255 GBV_USEFLAG_U SYSFLAG_U GBV_ELV GBV_ILN_20 GBV_ILN_22 GBV_ILN_23 GBV_ILN_24 GBV_ILN_31 GBV_ILN_39 GBV_ILN_40 GBV_ILN_60 GBV_ILN_62 GBV_ILN_63 GBV_ILN_65 GBV_ILN_69 GBV_ILN_73 GBV_ILN_74 GBV_ILN_95 GBV_ILN_105 GBV_ILN_110 GBV_ILN_151 GBV_ILN_161 GBV_ILN_170 GBV_ILN_206 GBV_ILN_213 GBV_ILN_230 GBV_ILN_285 GBV_ILN_293 GBV_ILN_602 GBV_ILN_2014 GBV_ILN_4012 GBV_ILN_4037 GBV_ILN_4112 GBV_ILN_4125 GBV_ILN_4126 GBV_ILN_4249 GBV_ILN_4305 GBV_ILN_4306 GBV_ILN_4307 GBV_ILN_4313 GBV_ILN_4322 GBV_ILN_4323 GBV_ILN_4324 GBV_ILN_4325 GBV_ILN_4338 GBV_ILN_4367 GBV_ILN_4700 44.65 Chirurgie AR 42 251-255
spelling	10.1016/j.asjsur.2018.03.002 doi (DE-627)ELV001290479 (ELSEVIER)S1015-9584(17)30660-7 DE-627 ger DE-627 rda eng 610 DE-101 610 DE-600 44.65 bkl Fujii, Yoshiro verfasserin aut Risk factors for hepatic insufficiency after major hepatectomy in non-cirrhotic patients 2018 nicht spezifiziert zzz rdacontent Computermedien c rdamedia Online-Ressource cr rdacarrier Background: Although recent advances in surgical techniques and perioperative management have reduced the morbidity and mortality after hepatectomy, hepatic insufficiency after major hepatectomy remains an important concern. This study aimed to clarify the risk factors for post-hepatectomy liver insufficiency.Methods: We enrolled 103 consecutive patients who underwent major hepatectomy which was defined as resection of four or more segments. Hepatic insufficiency is defined as an increase in serum total bilirubin after hepatectomy of 7 mg/dL or more, or death from multiple organ failure. We compared the patient disposition, demographics, perioperative factors such as surgical method, combined procedure, morbidity and so on between the patients with or without hepatic insufficiency.Results: Hepatic insufficiency occurred in 14 patients (14%) and six of them died during the hospital stay (6%). Risk factors by univariate analysis were the percentage of hepatic parenchyma to be resected (P = .025), combined procedure (P = .008) and postoperative morbidity excluding hepatic insufficiency (P < .001). A combined procedure (P = .036) and postoperative morbidity excluding hepatic insufficiency (P = .002) were a significant risk factor by multivariate analysis.Conclusion: Unless remaining liver after hepatectomy has enough volume, combined procedure may account for hepatic insufficiency, which can follow the development of postoperative morbidity. Risk factor Hepatic insufficiency Major hepatectomy Nanashima, Atsushi verfasserin aut Hiyoshi, Masahide verfasserin (orcid)0000-0002-2392-7787 aut Imamura, Naoya verfasserin aut Yano, Koichi verfasserin aut Hamada, Takeomi verfasserin aut Enthalten in Asian journal of surgery Hong Kong : Excerpta Medica Asia, 2000 42, Seite 251-255 Online-Ressource (DE-627)324827164 (DE-600)2031317-2 (DE-576)272711896 0219-3108 nnns volume:42 pages:251-255 GBV_USEFLAG_U SYSFLAG_U GBV_ELV GBV_ILN_20 GBV_ILN_22 GBV_ILN_23 GBV_ILN_24 GBV_ILN_31 GBV_ILN_39 GBV_ILN_40 GBV_ILN_60 GBV_ILN_62 GBV_ILN_63 GBV_ILN_65 GBV_ILN_69 GBV_ILN_73 GBV_ILN_74 GBV_ILN_95 GBV_ILN_105 GBV_ILN_110 GBV_ILN_151 GBV_ILN_161 GBV_ILN_170 GBV_ILN_206 GBV_ILN_213 GBV_ILN_230 GBV_ILN_285 GBV_ILN_293 GBV_ILN_602 GBV_ILN_2014 GBV_ILN_4012 GBV_ILN_4037 GBV_ILN_4112 GBV_ILN_4125 GBV_ILN_4126 GBV_ILN_4249 GBV_ILN_4305 GBV_ILN_4306 GBV_ILN_4307 GBV_ILN_4313 GBV_ILN_4322 GBV_ILN_4323 GBV_ILN_4324 GBV_ILN_4325 GBV_ILN_4338 GBV_ILN_4367 GBV_ILN_4700 44.65 Chirurgie AR 42 251-255
allfields_unstemmed	10.1016/j.asjsur.2018.03.002 doi (DE-627)ELV001290479 (ELSEVIER)S1015-9584(17)30660-7 DE-627 ger DE-627 rda eng 610 DE-101 610 DE-600 44.65 bkl Fujii, Yoshiro verfasserin aut Risk factors for hepatic insufficiency after major hepatectomy in non-cirrhotic patients 2018 nicht spezifiziert zzz rdacontent Computermedien c rdamedia Online-Ressource cr rdacarrier Background: Although recent advances in surgical techniques and perioperative management have reduced the morbidity and mortality after hepatectomy, hepatic insufficiency after major hepatectomy remains an important concern. This study aimed to clarify the risk factors for post-hepatectomy liver insufficiency.Methods: We enrolled 103 consecutive patients who underwent major hepatectomy which was defined as resection of four or more segments. Hepatic insufficiency is defined as an increase in serum total bilirubin after hepatectomy of 7 mg/dL or more, or death from multiple organ failure. We compared the patient disposition, demographics, perioperative factors such as surgical method, combined procedure, morbidity and so on between the patients with or without hepatic insufficiency.Results: Hepatic insufficiency occurred in 14 patients (14%) and six of them died during the hospital stay (6%). Risk factors by univariate analysis were the percentage of hepatic parenchyma to be resected (P = .025), combined procedure (P = .008) and postoperative morbidity excluding hepatic insufficiency (P < .001). A combined procedure (P = .036) and postoperative morbidity excluding hepatic insufficiency (P = .002) were a significant risk factor by multivariate analysis.Conclusion: Unless remaining liver after hepatectomy has enough volume, combined procedure may account for hepatic insufficiency, which can follow the development of postoperative morbidity. Risk factor Hepatic insufficiency Major hepatectomy Nanashima, Atsushi verfasserin aut Hiyoshi, Masahide verfasserin (orcid)0000-0002-2392-7787 aut Imamura, Naoya verfasserin aut Yano, Koichi verfasserin aut Hamada, Takeomi verfasserin aut Enthalten in Asian journal of surgery Hong Kong : Excerpta Medica Asia, 2000 42, Seite 251-255 Online-Ressource (DE-627)324827164 (DE-600)2031317-2 (DE-576)272711896 0219-3108 nnns volume:42 pages:251-255 GBV_USEFLAG_U SYSFLAG_U GBV_ELV GBV_ILN_20 GBV_ILN_22 GBV_ILN_23 GBV_ILN_24 GBV_ILN_31 GBV_ILN_39 GBV_ILN_40 GBV_ILN_60 GBV_ILN_62 GBV_ILN_63 GBV_ILN_65 GBV_ILN_69 GBV_ILN_73 GBV_ILN_74 GBV_ILN_95 GBV_ILN_105 GBV_ILN_110 GBV_ILN_151 GBV_ILN_161 GBV_ILN_170 GBV_ILN_206 GBV_ILN_213 GBV_ILN_230 GBV_ILN_285 GBV_ILN_293 GBV_ILN_602 GBV_ILN_2014 GBV_ILN_4012 GBV_ILN_4037 GBV_ILN_4112 GBV_ILN_4125 GBV_ILN_4126 GBV_ILN_4249 GBV_ILN_4305 GBV_ILN_4306 GBV_ILN_4307 GBV_ILN_4313 GBV_ILN_4322 GBV_ILN_4323 GBV_ILN_4324 GBV_ILN_4325 GBV_ILN_4338 GBV_ILN_4367 GBV_ILN_4700 44.65 Chirurgie AR 42 251-255
allfieldsGer	10.1016/j.asjsur.2018.03.002 doi (DE-627)ELV001290479 (ELSEVIER)S1015-9584(17)30660-7 DE-627 ger DE-627 rda eng 610 DE-101 610 DE-600 44.65 bkl Fujii, Yoshiro verfasserin aut Risk factors for hepatic insufficiency after major hepatectomy in non-cirrhotic patients 2018 nicht spezifiziert zzz rdacontent Computermedien c rdamedia Online-Ressource cr rdacarrier Background: Although recent advances in surgical techniques and perioperative management have reduced the morbidity and mortality after hepatectomy, hepatic insufficiency after major hepatectomy remains an important concern. This study aimed to clarify the risk factors for post-hepatectomy liver insufficiency.Methods: We enrolled 103 consecutive patients who underwent major hepatectomy which was defined as resection of four or more segments. Hepatic insufficiency is defined as an increase in serum total bilirubin after hepatectomy of 7 mg/dL or more, or death from multiple organ failure. We compared the patient disposition, demographics, perioperative factors such as surgical method, combined procedure, morbidity and so on between the patients with or without hepatic insufficiency.Results: Hepatic insufficiency occurred in 14 patients (14%) and six of them died during the hospital stay (6%). Risk factors by univariate analysis were the percentage of hepatic parenchyma to be resected (P = .025), combined procedure (P = .008) and postoperative morbidity excluding hepatic insufficiency (P < .001). A combined procedure (P = .036) and postoperative morbidity excluding hepatic insufficiency (P = .002) were a significant risk factor by multivariate analysis.Conclusion: Unless remaining liver after hepatectomy has enough volume, combined procedure may account for hepatic insufficiency, which can follow the development of postoperative morbidity. Risk factor Hepatic insufficiency Major hepatectomy Nanashima, Atsushi verfasserin aut Hiyoshi, Masahide verfasserin (orcid)0000-0002-2392-7787 aut Imamura, Naoya verfasserin aut Yano, Koichi verfasserin aut Hamada, Takeomi verfasserin aut Enthalten in Asian journal of surgery Hong Kong : Excerpta Medica Asia, 2000 42, Seite 251-255 Online-Ressource (DE-627)324827164 (DE-600)2031317-2 (DE-576)272711896 0219-3108 nnns volume:42 pages:251-255 GBV_USEFLAG_U SYSFLAG_U GBV_ELV GBV_ILN_20 GBV_ILN_22 GBV_ILN_23 GBV_ILN_24 GBV_ILN_31 GBV_ILN_39 GBV_ILN_40 GBV_ILN_60 GBV_ILN_62 GBV_ILN_63 GBV_ILN_65 GBV_ILN_69 GBV_ILN_73 GBV_ILN_74 GBV_ILN_95 GBV_ILN_105 GBV_ILN_110 GBV_ILN_151 GBV_ILN_161 GBV_ILN_170 GBV_ILN_206 GBV_ILN_213 GBV_ILN_230 GBV_ILN_285 GBV_ILN_293 GBV_ILN_602 GBV_ILN_2014 GBV_ILN_4012 GBV_ILN_4037 GBV_ILN_4112 GBV_ILN_4125 GBV_ILN_4126 GBV_ILN_4249 GBV_ILN_4305 GBV_ILN_4306 GBV_ILN_4307 GBV_ILN_4313 GBV_ILN_4322 GBV_ILN_4323 GBV_ILN_4324 GBV_ILN_4325 GBV_ILN_4338 GBV_ILN_4367 GBV_ILN_4700 44.65 Chirurgie AR 42 251-255
allfieldsSound	10.1016/j.asjsur.2018.03.002 doi (DE-627)ELV001290479 (ELSEVIER)S1015-9584(17)30660-7 DE-627 ger DE-627 rda eng 610 DE-101 610 DE-600 44.65 bkl Fujii, Yoshiro verfasserin aut Risk factors for hepatic insufficiency after major hepatectomy in non-cirrhotic patients 2018 nicht spezifiziert zzz rdacontent Computermedien c rdamedia Online-Ressource cr rdacarrier Background: Although recent advances in surgical techniques and perioperative management have reduced the morbidity and mortality after hepatectomy, hepatic insufficiency after major hepatectomy remains an important concern. This study aimed to clarify the risk factors for post-hepatectomy liver insufficiency.Methods: We enrolled 103 consecutive patients who underwent major hepatectomy which was defined as resection of four or more segments. Hepatic insufficiency is defined as an increase in serum total bilirubin after hepatectomy of 7 mg/dL or more, or death from multiple organ failure. We compared the patient disposition, demographics, perioperative factors such as surgical method, combined procedure, morbidity and so on between the patients with or without hepatic insufficiency.Results: Hepatic insufficiency occurred in 14 patients (14%) and six of them died during the hospital stay (6%). Risk factors by univariate analysis were the percentage of hepatic parenchyma to be resected (P = .025), combined procedure (P = .008) and postoperative morbidity excluding hepatic insufficiency (P < .001). A combined procedure (P = .036) and postoperative morbidity excluding hepatic insufficiency (P = .002) were a significant risk factor by multivariate analysis.Conclusion: Unless remaining liver after hepatectomy has enough volume, combined procedure may account for hepatic insufficiency, which can follow the development of postoperative morbidity. Risk factor Hepatic insufficiency Major hepatectomy Nanashima, Atsushi verfasserin aut Hiyoshi, Masahide verfasserin (orcid)0000-0002-2392-7787 aut Imamura, Naoya verfasserin aut Yano, Koichi verfasserin aut Hamada, Takeomi verfasserin aut Enthalten in Asian journal of surgery Hong Kong : Excerpta Medica Asia, 2000 42, Seite 251-255 Online-Ressource (DE-627)324827164 (DE-600)2031317-2 (DE-576)272711896 0219-3108 nnns volume:42 pages:251-255 GBV_USEFLAG_U SYSFLAG_U GBV_ELV GBV_ILN_20 GBV_ILN_22 GBV_ILN_23 GBV_ILN_24 GBV_ILN_31 GBV_ILN_39 GBV_ILN_40 GBV_ILN_60 GBV_ILN_62 GBV_ILN_63 GBV_ILN_65 GBV_ILN_69 GBV_ILN_73 GBV_ILN_74 GBV_ILN_95 GBV_ILN_105 GBV_ILN_110 GBV_ILN_151 GBV_ILN_161 GBV_ILN_170 GBV_ILN_206 GBV_ILN_213 GBV_ILN_230 GBV_ILN_285 GBV_ILN_293 GBV_ILN_602 GBV_ILN_2014 GBV_ILN_4012 GBV_ILN_4037 GBV_ILN_4112 GBV_ILN_4125 GBV_ILN_4126 GBV_ILN_4249 GBV_ILN_4305 GBV_ILN_4306 GBV_ILN_4307 GBV_ILN_4313 GBV_ILN_4322 GBV_ILN_4323 GBV_ILN_4324 GBV_ILN_4325 GBV_ILN_4338 GBV_ILN_4367 GBV_ILN_4700 44.65 Chirurgie AR 42 251-255
language	English
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authorswithroles_txt_mv	Fujii, Yoshiro @@aut@@ Nanashima, Atsushi @@aut@@ Hiyoshi, Masahide @@aut@@ Imamura, Naoya @@aut@@ Yano, Koichi @@aut@@ Hamada, Takeomi @@aut@@
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author	Fujii, Yoshiro
spellingShingle	Fujii, Yoshiro ddc 610 bkl 44.65 misc Risk factor misc Hepatic insufficiency misc Major hepatectomy Risk factors for hepatic insufficiency after major hepatectomy in non-cirrhotic patients
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topic_title	610 DE-101 610 DE-600 44.65 bkl Risk factors for hepatic insufficiency after major hepatectomy in non-cirrhotic patients Risk factor Hepatic insufficiency Major hepatectomy
topic	ddc 610 bkl 44.65 misc Risk factor misc Hepatic insufficiency misc Major hepatectomy
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title	Risk factors for hepatic insufficiency after major hepatectomy in non-cirrhotic patients
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title_full	Risk factors for hepatic insufficiency after major hepatectomy in non-cirrhotic patients
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journal	Asian journal of surgery
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author_browse	Fujii, Yoshiro Nanashima, Atsushi Hiyoshi, Masahide Imamura, Naoya Yano, Koichi Hamada, Takeomi
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title_sort	risk factors for hepatic insufficiency after major hepatectomy in non-cirrhotic patients
title_auth	Risk factors for hepatic insufficiency after major hepatectomy in non-cirrhotic patients
abstract	Background: Although recent advances in surgical techniques and perioperative management have reduced the morbidity and mortality after hepatectomy, hepatic insufficiency after major hepatectomy remains an important concern. This study aimed to clarify the risk factors for post-hepatectomy liver insufficiency.Methods: We enrolled 103 consecutive patients who underwent major hepatectomy which was defined as resection of four or more segments. Hepatic insufficiency is defined as an increase in serum total bilirubin after hepatectomy of 7 mg/dL or more, or death from multiple organ failure. We compared the patient disposition, demographics, perioperative factors such as surgical method, combined procedure, morbidity and so on between the patients with or without hepatic insufficiency.Results: Hepatic insufficiency occurred in 14 patients (14%) and six of them died during the hospital stay (6%). Risk factors by univariate analysis were the percentage of hepatic parenchyma to be resected (P = .025), combined procedure (P = .008) and postoperative morbidity excluding hepatic insufficiency (P < .001). A combined procedure (P = .036) and postoperative morbidity excluding hepatic insufficiency (P = .002) were a significant risk factor by multivariate analysis.Conclusion: Unless remaining liver after hepatectomy has enough volume, combined procedure may account for hepatic insufficiency, which can follow the development of postoperative morbidity.
abstractGer	Background: Although recent advances in surgical techniques and perioperative management have reduced the morbidity and mortality after hepatectomy, hepatic insufficiency after major hepatectomy remains an important concern. This study aimed to clarify the risk factors for post-hepatectomy liver insufficiency.Methods: We enrolled 103 consecutive patients who underwent major hepatectomy which was defined as resection of four or more segments. Hepatic insufficiency is defined as an increase in serum total bilirubin after hepatectomy of 7 mg/dL or more, or death from multiple organ failure. We compared the patient disposition, demographics, perioperative factors such as surgical method, combined procedure, morbidity and so on between the patients with or without hepatic insufficiency.Results: Hepatic insufficiency occurred in 14 patients (14%) and six of them died during the hospital stay (6%). Risk factors by univariate analysis were the percentage of hepatic parenchyma to be resected (P = .025), combined procedure (P = .008) and postoperative morbidity excluding hepatic insufficiency (P < .001). A combined procedure (P = .036) and postoperative morbidity excluding hepatic insufficiency (P = .002) were a significant risk factor by multivariate analysis.Conclusion: Unless remaining liver after hepatectomy has enough volume, combined procedure may account for hepatic insufficiency, which can follow the development of postoperative morbidity.
abstract_unstemmed	Background: Although recent advances in surgical techniques and perioperative management have reduced the morbidity and mortality after hepatectomy, hepatic insufficiency after major hepatectomy remains an important concern. This study aimed to clarify the risk factors for post-hepatectomy liver insufficiency.Methods: We enrolled 103 consecutive patients who underwent major hepatectomy which was defined as resection of four or more segments. Hepatic insufficiency is defined as an increase in serum total bilirubin after hepatectomy of 7 mg/dL or more, or death from multiple organ failure. We compared the patient disposition, demographics, perioperative factors such as surgical method, combined procedure, morbidity and so on between the patients with or without hepatic insufficiency.Results: Hepatic insufficiency occurred in 14 patients (14%) and six of them died during the hospital stay (6%). Risk factors by univariate analysis were the percentage of hepatic parenchyma to be resected (P = .025), combined procedure (P = .008) and postoperative morbidity excluding hepatic insufficiency (P < .001). A combined procedure (P = .036) and postoperative morbidity excluding hepatic insufficiency (P = .002) were a significant risk factor by multivariate analysis.Conclusion: Unless remaining liver after hepatectomy has enough volume, combined procedure may account for hepatic insufficiency, which can follow the development of postoperative morbidity.
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title_short	Risk factors for hepatic insufficiency after major hepatectomy in non-cirrhotic patients
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author2	Nanashima, Atsushi Hiyoshi, Masahide Imamura, Naoya Yano, Koichi Hamada, Takeomi
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up_date	2024-07-06T20:52:17.351Z
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Risk factors for hepatic insufficiency after major hepatectomy in non-cirrhotic patients

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