Assessment of esophageal function using provocative tests during high resolution manometry: A single-center experience

Background: Provocative tests were used to provide additional information during performing high resolution manometry (HRM). The study aimed to evaluate whether it is feasible to test esophageal function with different esophageal provocative tests during HRM.Methods: 23 healthy volunteers (9 women;...
Ausführliche Beschreibung

Gespeichert in:

Autor*in:	Wong, Ming-Wun [verfasserIn] Lei, Wei-Yi [verfasserIn] Hung, Jui-Sheng [verfasserIn] Liu, Tso-Tsai [verfasserIn] Yi, Chih-Hsun [verfasserIn] Chen, Chien-Lin [verfasserIn]

Format:	E-Artikel
Sprache:	Englisch

Erschienen:	2018

Schlagwörter:	High resolution manometry Esophageal manometry Esophageal motility

Übergeordnetes Werk:	Enthalten in: Journal of the Formosan Medical Association - Tai wan yi xue hui ; ID: gnd/1042770-3, Hong Kong : Elsevier, 2006, 118, Seite 244-248
Übergeordnetes Werk:	volume:118 ; pages:244-248

DOI / URN:	10.1016/j.jfma.2018.04.010

Katalog-ID:	ELV001379879

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245	1	0	\|a Assessment of esophageal function using provocative tests during high resolution manometry: A single-center experience
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520			\|a Background: Provocative tests were used to provide additional information during performing high resolution manometry (HRM). The study aimed to evaluate whether it is feasible to test esophageal function with different esophageal provocative tests during HRM.Methods: 23 healthy volunteers (9 women; mean age 25 years, range 21–30 years) underwent water-perfused HRM. Each subject received 10 liquid swallows, 10 solid swallows, 10 liquid swallows with abdominal compression, and 5 multiple rapid swallowing (MRS).Results: DCI was significantly greater during abdominal compression than that of solid swallows (p = 0.025). Compared with liquid swallows, there was a significant decrease in CFV during solid swallows (p = 0.04). DL was significantly greater during solid swallows than that of liquid swallows (p < 0.001) or abdominal compression (p < 0.001). IRP 4s was significantly lower during abdominal compression than that of liquids (p < 0.001) or solid swallows (p = 0.006). All subjects had complete inhibition during MRS and increased DCI after MRS as compared with liquid swallows (p < 0.05).Conclusion: Esophageal provocative test may provide additional utility in performing HRM studies. The data for esophageal provocative tests are distinct from standard liquid swallows.
650		4	\|a High resolution manometry
650		4	\|a Esophageal manometry
650		4	\|a Esophageal motility
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700	1		\|a Chen, Chien-Lin \|e verfasserin \|4 aut
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allfields	10.1016/j.jfma.2018.04.010 doi (DE-627)ELV001379879 (ELSEVIER)S0929-6646(18)30051-2 DE-627 ger DE-627 rda eng 610 DE-600 44.04 bkl Wong, Ming-Wun verfasserin aut Assessment of esophageal function using provocative tests during high resolution manometry: A single-center experience 2018 nicht spezifiziert zzz rdacontent Computermedien c rdamedia Online-Ressource cr rdacarrier Background: Provocative tests were used to provide additional information during performing high resolution manometry (HRM). The study aimed to evaluate whether it is feasible to test esophageal function with different esophageal provocative tests during HRM.Methods: 23 healthy volunteers (9 women; mean age 25 years, range 21–30 years) underwent water-perfused HRM. Each subject received 10 liquid swallows, 10 solid swallows, 10 liquid swallows with abdominal compression, and 5 multiple rapid swallowing (MRS).Results: DCI was significantly greater during abdominal compression than that of solid swallows (p = 0.025). Compared with liquid swallows, there was a significant decrease in CFV during solid swallows (p = 0.04). DL was significantly greater during solid swallows than that of liquid swallows (p < 0.001) or abdominal compression (p < 0.001). IRP 4s was significantly lower during abdominal compression than that of liquids (p < 0.001) or solid swallows (p = 0.006). All subjects had complete inhibition during MRS and increased DCI after MRS as compared with liquid swallows (p < 0.05).Conclusion: Esophageal provocative test may provide additional utility in performing HRM studies. The data for esophageal provocative tests are distinct from standard liquid swallows. High resolution manometry Esophageal manometry Esophageal motility Lei, Wei-Yi verfasserin aut Hung, Jui-Sheng verfasserin aut Liu, Tso-Tsai verfasserin aut Yi, Chih-Hsun verfasserin aut Chen, Chien-Lin verfasserin aut Enthalten in Tai wan yi xue hui ; ID: gnd/1042770-3 Journal of the Formosan Medical Association Hong Kong : Elsevier, 2006 118, Seite 244-248 Online-Ressource (DE-627)517812649 (DE-600)2250901-X (DE-576)272713511 1876-0821 nnns volume:118 pages:244-248 GBV_USEFLAG_U SYSFLAG_U GBV_ELV SSG-OLC-PHA GBV_ILN_20 GBV_ILN_22 GBV_ILN_23 GBV_ILN_24 GBV_ILN_31 GBV_ILN_39 GBV_ILN_40 GBV_ILN_60 GBV_ILN_62 GBV_ILN_63 GBV_ILN_65 GBV_ILN_69 GBV_ILN_73 GBV_ILN_74 GBV_ILN_95 GBV_ILN_100 GBV_ILN_105 GBV_ILN_110 GBV_ILN_151 GBV_ILN_161 GBV_ILN_170 GBV_ILN_206 GBV_ILN_213 GBV_ILN_230 GBV_ILN_285 GBV_ILN_293 GBV_ILN_602 GBV_ILN_2004 GBV_ILN_2014 GBV_ILN_2068 GBV_ILN_4012 GBV_ILN_4037 GBV_ILN_4112 GBV_ILN_4125 GBV_ILN_4126 GBV_ILN_4249 GBV_ILN_4305 GBV_ILN_4306 GBV_ILN_4307 GBV_ILN_4313 GBV_ILN_4322 GBV_ILN_4323 GBV_ILN_4324 GBV_ILN_4325 GBV_ILN_4338 GBV_ILN_4367 GBV_ILN_4700 44.04 Ausbildung Beruf Organisationen Medizin AR 118 244-248
spelling	10.1016/j.jfma.2018.04.010 doi (DE-627)ELV001379879 (ELSEVIER)S0929-6646(18)30051-2 DE-627 ger DE-627 rda eng 610 DE-600 44.04 bkl Wong, Ming-Wun verfasserin aut Assessment of esophageal function using provocative tests during high resolution manometry: A single-center experience 2018 nicht spezifiziert zzz rdacontent Computermedien c rdamedia Online-Ressource cr rdacarrier Background: Provocative tests were used to provide additional information during performing high resolution manometry (HRM). The study aimed to evaluate whether it is feasible to test esophageal function with different esophageal provocative tests during HRM.Methods: 23 healthy volunteers (9 women; mean age 25 years, range 21–30 years) underwent water-perfused HRM. Each subject received 10 liquid swallows, 10 solid swallows, 10 liquid swallows with abdominal compression, and 5 multiple rapid swallowing (MRS).Results: DCI was significantly greater during abdominal compression than that of solid swallows (p = 0.025). Compared with liquid swallows, there was a significant decrease in CFV during solid swallows (p = 0.04). DL was significantly greater during solid swallows than that of liquid swallows (p < 0.001) or abdominal compression (p < 0.001). IRP 4s was significantly lower during abdominal compression than that of liquids (p < 0.001) or solid swallows (p = 0.006). All subjects had complete inhibition during MRS and increased DCI after MRS as compared with liquid swallows (p < 0.05).Conclusion: Esophageal provocative test may provide additional utility in performing HRM studies. The data for esophageal provocative tests are distinct from standard liquid swallows. High resolution manometry Esophageal manometry Esophageal motility Lei, Wei-Yi verfasserin aut Hung, Jui-Sheng verfasserin aut Liu, Tso-Tsai verfasserin aut Yi, Chih-Hsun verfasserin aut Chen, Chien-Lin verfasserin aut Enthalten in Tai wan yi xue hui ; ID: gnd/1042770-3 Journal of the Formosan Medical Association Hong Kong : Elsevier, 2006 118, Seite 244-248 Online-Ressource (DE-627)517812649 (DE-600)2250901-X (DE-576)272713511 1876-0821 nnns volume:118 pages:244-248 GBV_USEFLAG_U SYSFLAG_U GBV_ELV SSG-OLC-PHA GBV_ILN_20 GBV_ILN_22 GBV_ILN_23 GBV_ILN_24 GBV_ILN_31 GBV_ILN_39 GBV_ILN_40 GBV_ILN_60 GBV_ILN_62 GBV_ILN_63 GBV_ILN_65 GBV_ILN_69 GBV_ILN_73 GBV_ILN_74 GBV_ILN_95 GBV_ILN_100 GBV_ILN_105 GBV_ILN_110 GBV_ILN_151 GBV_ILN_161 GBV_ILN_170 GBV_ILN_206 GBV_ILN_213 GBV_ILN_230 GBV_ILN_285 GBV_ILN_293 GBV_ILN_602 GBV_ILN_2004 GBV_ILN_2014 GBV_ILN_2068 GBV_ILN_4012 GBV_ILN_4037 GBV_ILN_4112 GBV_ILN_4125 GBV_ILN_4126 GBV_ILN_4249 GBV_ILN_4305 GBV_ILN_4306 GBV_ILN_4307 GBV_ILN_4313 GBV_ILN_4322 GBV_ILN_4323 GBV_ILN_4324 GBV_ILN_4325 GBV_ILN_4338 GBV_ILN_4367 GBV_ILN_4700 44.04 Ausbildung Beruf Organisationen Medizin AR 118 244-248
allfields_unstemmed	10.1016/j.jfma.2018.04.010 doi (DE-627)ELV001379879 (ELSEVIER)S0929-6646(18)30051-2 DE-627 ger DE-627 rda eng 610 DE-600 44.04 bkl Wong, Ming-Wun verfasserin aut Assessment of esophageal function using provocative tests during high resolution manometry: A single-center experience 2018 nicht spezifiziert zzz rdacontent Computermedien c rdamedia Online-Ressource cr rdacarrier Background: Provocative tests were used to provide additional information during performing high resolution manometry (HRM). The study aimed to evaluate whether it is feasible to test esophageal function with different esophageal provocative tests during HRM.Methods: 23 healthy volunteers (9 women; mean age 25 years, range 21–30 years) underwent water-perfused HRM. Each subject received 10 liquid swallows, 10 solid swallows, 10 liquid swallows with abdominal compression, and 5 multiple rapid swallowing (MRS).Results: DCI was significantly greater during abdominal compression than that of solid swallows (p = 0.025). Compared with liquid swallows, there was a significant decrease in CFV during solid swallows (p = 0.04). DL was significantly greater during solid swallows than that of liquid swallows (p < 0.001) or abdominal compression (p < 0.001). IRP 4s was significantly lower during abdominal compression than that of liquids (p < 0.001) or solid swallows (p = 0.006). All subjects had complete inhibition during MRS and increased DCI after MRS as compared with liquid swallows (p < 0.05).Conclusion: Esophageal provocative test may provide additional utility in performing HRM studies. The data for esophageal provocative tests are distinct from standard liquid swallows. High resolution manometry Esophageal manometry Esophageal motility Lei, Wei-Yi verfasserin aut Hung, Jui-Sheng verfasserin aut Liu, Tso-Tsai verfasserin aut Yi, Chih-Hsun verfasserin aut Chen, Chien-Lin verfasserin aut Enthalten in Tai wan yi xue hui ; ID: gnd/1042770-3 Journal of the Formosan Medical Association Hong Kong : Elsevier, 2006 118, Seite 244-248 Online-Ressource (DE-627)517812649 (DE-600)2250901-X (DE-576)272713511 1876-0821 nnns volume:118 pages:244-248 GBV_USEFLAG_U SYSFLAG_U GBV_ELV SSG-OLC-PHA GBV_ILN_20 GBV_ILN_22 GBV_ILN_23 GBV_ILN_24 GBV_ILN_31 GBV_ILN_39 GBV_ILN_40 GBV_ILN_60 GBV_ILN_62 GBV_ILN_63 GBV_ILN_65 GBV_ILN_69 GBV_ILN_73 GBV_ILN_74 GBV_ILN_95 GBV_ILN_100 GBV_ILN_105 GBV_ILN_110 GBV_ILN_151 GBV_ILN_161 GBV_ILN_170 GBV_ILN_206 GBV_ILN_213 GBV_ILN_230 GBV_ILN_285 GBV_ILN_293 GBV_ILN_602 GBV_ILN_2004 GBV_ILN_2014 GBV_ILN_2068 GBV_ILN_4012 GBV_ILN_4037 GBV_ILN_4112 GBV_ILN_4125 GBV_ILN_4126 GBV_ILN_4249 GBV_ILN_4305 GBV_ILN_4306 GBV_ILN_4307 GBV_ILN_4313 GBV_ILN_4322 GBV_ILN_4323 GBV_ILN_4324 GBV_ILN_4325 GBV_ILN_4338 GBV_ILN_4367 GBV_ILN_4700 44.04 Ausbildung Beruf Organisationen Medizin AR 118 244-248
allfieldsGer	10.1016/j.jfma.2018.04.010 doi (DE-627)ELV001379879 (ELSEVIER)S0929-6646(18)30051-2 DE-627 ger DE-627 rda eng 610 DE-600 44.04 bkl Wong, Ming-Wun verfasserin aut Assessment of esophageal function using provocative tests during high resolution manometry: A single-center experience 2018 nicht spezifiziert zzz rdacontent Computermedien c rdamedia Online-Ressource cr rdacarrier Background: Provocative tests were used to provide additional information during performing high resolution manometry (HRM). The study aimed to evaluate whether it is feasible to test esophageal function with different esophageal provocative tests during HRM.Methods: 23 healthy volunteers (9 women; mean age 25 years, range 21–30 years) underwent water-perfused HRM. Each subject received 10 liquid swallows, 10 solid swallows, 10 liquid swallows with abdominal compression, and 5 multiple rapid swallowing (MRS).Results: DCI was significantly greater during abdominal compression than that of solid swallows (p = 0.025). Compared with liquid swallows, there was a significant decrease in CFV during solid swallows (p = 0.04). DL was significantly greater during solid swallows than that of liquid swallows (p < 0.001) or abdominal compression (p < 0.001). IRP 4s was significantly lower during abdominal compression than that of liquids (p < 0.001) or solid swallows (p = 0.006). All subjects had complete inhibition during MRS and increased DCI after MRS as compared with liquid swallows (p < 0.05).Conclusion: Esophageal provocative test may provide additional utility in performing HRM studies. The data for esophageal provocative tests are distinct from standard liquid swallows. High resolution manometry Esophageal manometry Esophageal motility Lei, Wei-Yi verfasserin aut Hung, Jui-Sheng verfasserin aut Liu, Tso-Tsai verfasserin aut Yi, Chih-Hsun verfasserin aut Chen, Chien-Lin verfasserin aut Enthalten in Tai wan yi xue hui ; ID: gnd/1042770-3 Journal of the Formosan Medical Association Hong Kong : Elsevier, 2006 118, Seite 244-248 Online-Ressource (DE-627)517812649 (DE-600)2250901-X (DE-576)272713511 1876-0821 nnns volume:118 pages:244-248 GBV_USEFLAG_U SYSFLAG_U GBV_ELV SSG-OLC-PHA GBV_ILN_20 GBV_ILN_22 GBV_ILN_23 GBV_ILN_24 GBV_ILN_31 GBV_ILN_39 GBV_ILN_40 GBV_ILN_60 GBV_ILN_62 GBV_ILN_63 GBV_ILN_65 GBV_ILN_69 GBV_ILN_73 GBV_ILN_74 GBV_ILN_95 GBV_ILN_100 GBV_ILN_105 GBV_ILN_110 GBV_ILN_151 GBV_ILN_161 GBV_ILN_170 GBV_ILN_206 GBV_ILN_213 GBV_ILN_230 GBV_ILN_285 GBV_ILN_293 GBV_ILN_602 GBV_ILN_2004 GBV_ILN_2014 GBV_ILN_2068 GBV_ILN_4012 GBV_ILN_4037 GBV_ILN_4112 GBV_ILN_4125 GBV_ILN_4126 GBV_ILN_4249 GBV_ILN_4305 GBV_ILN_4306 GBV_ILN_4307 GBV_ILN_4313 GBV_ILN_4322 GBV_ILN_4323 GBV_ILN_4324 GBV_ILN_4325 GBV_ILN_4338 GBV_ILN_4367 GBV_ILN_4700 44.04 Ausbildung Beruf Organisationen Medizin AR 118 244-248
allfieldsSound	10.1016/j.jfma.2018.04.010 doi (DE-627)ELV001379879 (ELSEVIER)S0929-6646(18)30051-2 DE-627 ger DE-627 rda eng 610 DE-600 44.04 bkl Wong, Ming-Wun verfasserin aut Assessment of esophageal function using provocative tests during high resolution manometry: A single-center experience 2018 nicht spezifiziert zzz rdacontent Computermedien c rdamedia Online-Ressource cr rdacarrier Background: Provocative tests were used to provide additional information during performing high resolution manometry (HRM). The study aimed to evaluate whether it is feasible to test esophageal function with different esophageal provocative tests during HRM.Methods: 23 healthy volunteers (9 women; mean age 25 years, range 21–30 years) underwent water-perfused HRM. Each subject received 10 liquid swallows, 10 solid swallows, 10 liquid swallows with abdominal compression, and 5 multiple rapid swallowing (MRS).Results: DCI was significantly greater during abdominal compression than that of solid swallows (p = 0.025). Compared with liquid swallows, there was a significant decrease in CFV during solid swallows (p = 0.04). DL was significantly greater during solid swallows than that of liquid swallows (p < 0.001) or abdominal compression (p < 0.001). IRP 4s was significantly lower during abdominal compression than that of liquids (p < 0.001) or solid swallows (p = 0.006). All subjects had complete inhibition during MRS and increased DCI after MRS as compared with liquid swallows (p < 0.05).Conclusion: Esophageal provocative test may provide additional utility in performing HRM studies. The data for esophageal provocative tests are distinct from standard liquid swallows. High resolution manometry Esophageal manometry Esophageal motility Lei, Wei-Yi verfasserin aut Hung, Jui-Sheng verfasserin aut Liu, Tso-Tsai verfasserin aut Yi, Chih-Hsun verfasserin aut Chen, Chien-Lin verfasserin aut Enthalten in Tai wan yi xue hui ; ID: gnd/1042770-3 Journal of the Formosan Medical Association Hong Kong : Elsevier, 2006 118, Seite 244-248 Online-Ressource (DE-627)517812649 (DE-600)2250901-X (DE-576)272713511 1876-0821 nnns volume:118 pages:244-248 GBV_USEFLAG_U SYSFLAG_U GBV_ELV SSG-OLC-PHA GBV_ILN_20 GBV_ILN_22 GBV_ILN_23 GBV_ILN_24 GBV_ILN_31 GBV_ILN_39 GBV_ILN_40 GBV_ILN_60 GBV_ILN_62 GBV_ILN_63 GBV_ILN_65 GBV_ILN_69 GBV_ILN_73 GBV_ILN_74 GBV_ILN_95 GBV_ILN_100 GBV_ILN_105 GBV_ILN_110 GBV_ILN_151 GBV_ILN_161 GBV_ILN_170 GBV_ILN_206 GBV_ILN_213 GBV_ILN_230 GBV_ILN_285 GBV_ILN_293 GBV_ILN_602 GBV_ILN_2004 GBV_ILN_2014 GBV_ILN_2068 GBV_ILN_4012 GBV_ILN_4037 GBV_ILN_4112 GBV_ILN_4125 GBV_ILN_4126 GBV_ILN_4249 GBV_ILN_4305 GBV_ILN_4306 GBV_ILN_4307 GBV_ILN_4313 GBV_ILN_4322 GBV_ILN_4323 GBV_ILN_4324 GBV_ILN_4325 GBV_ILN_4338 GBV_ILN_4367 GBV_ILN_4700 44.04 Ausbildung Beruf Organisationen Medizin AR 118 244-248
language	English
source	Enthalten in Journal of the Formosan Medical Association 118, Seite 244-248 volume:118 pages:244-248
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format_phy_str_mv	Article
bklname	Ausbildung Beruf Organisationen
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topic_facet	High resolution manometry Esophageal manometry Esophageal motility
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container_title	Journal of the Formosan Medical Association
authorswithroles_txt_mv	Wong, Ming-Wun @@aut@@ Lei, Wei-Yi @@aut@@ Hung, Jui-Sheng @@aut@@ Liu, Tso-Tsai @@aut@@ Yi, Chih-Hsun @@aut@@ Chen, Chien-Lin @@aut@@
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The study aimed to evaluate whether it is feasible to test esophageal function with different esophageal provocative tests during HRM.Methods: 23 healthy volunteers (9 women; mean age 25 years, range 21–30 years) underwent water-perfused HRM. Each subject received 10 liquid swallows, 10 solid swallows, 10 liquid swallows with abdominal compression, and 5 multiple rapid swallowing (MRS).Results: DCI was significantly greater during abdominal compression than that of solid swallows (p = 0.025). Compared with liquid swallows, there was a significant decrease in CFV during solid swallows (p = 0.04). DL was significantly greater during solid swallows than that of liquid swallows (p < 0.001) or abdominal compression (p < 0.001). IRP 4s was significantly lower during abdominal compression than that of liquids (p < 0.001) or solid swallows (p = 0.006). All subjects had complete inhibition during MRS and increased DCI after MRS as compared with liquid swallows (p < 0.05).Conclusion: Esophageal provocative test may provide additional utility in performing HRM studies. 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author	Wong, Ming-Wun
spellingShingle	Wong, Ming-Wun ddc 610 bkl 44.04 misc High resolution manometry misc Esophageal manometry misc Esophageal motility Assessment of esophageal function using provocative tests during high resolution manometry: A single-center experience
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topic_title	610 DE-600 44.04 bkl Assessment of esophageal function using provocative tests during high resolution manometry: A single-center experience High resolution manometry Esophageal manometry Esophageal motility
topic	ddc 610 bkl 44.04 misc High resolution manometry misc Esophageal manometry misc Esophageal motility
topic_unstemmed	ddc 610 bkl 44.04 misc High resolution manometry misc Esophageal manometry misc Esophageal motility
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title	Assessment of esophageal function using provocative tests during high resolution manometry: A single-center experience
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title_full	Assessment of esophageal function using provocative tests during high resolution manometry: A single-center experience
author_sort	Wong, Ming-Wun
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author_browse	Wong, Ming-Wun Lei, Wei-Yi Hung, Jui-Sheng Liu, Tso-Tsai Yi, Chih-Hsun Chen, Chien-Lin
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dewey-full	610
author2-role	verfasserin
title_sort	assessment of esophageal function using provocative tests during high resolution manometry: a single-center experience
title_auth	Assessment of esophageal function using provocative tests during high resolution manometry: A single-center experience
abstract	Background: Provocative tests were used to provide additional information during performing high resolution manometry (HRM). The study aimed to evaluate whether it is feasible to test esophageal function with different esophageal provocative tests during HRM.Methods: 23 healthy volunteers (9 women; mean age 25 years, range 21–30 years) underwent water-perfused HRM. Each subject received 10 liquid swallows, 10 solid swallows, 10 liquid swallows with abdominal compression, and 5 multiple rapid swallowing (MRS).Results: DCI was significantly greater during abdominal compression than that of solid swallows (p = 0.025). Compared with liquid swallows, there was a significant decrease in CFV during solid swallows (p = 0.04). DL was significantly greater during solid swallows than that of liquid swallows (p < 0.001) or abdominal compression (p < 0.001). IRP 4s was significantly lower during abdominal compression than that of liquids (p < 0.001) or solid swallows (p = 0.006). All subjects had complete inhibition during MRS and increased DCI after MRS as compared with liquid swallows (p < 0.05).Conclusion: Esophageal provocative test may provide additional utility in performing HRM studies. The data for esophageal provocative tests are distinct from standard liquid swallows.
abstractGer	Background: Provocative tests were used to provide additional information during performing high resolution manometry (HRM). The study aimed to evaluate whether it is feasible to test esophageal function with different esophageal provocative tests during HRM.Methods: 23 healthy volunteers (9 women; mean age 25 years, range 21–30 years) underwent water-perfused HRM. Each subject received 10 liquid swallows, 10 solid swallows, 10 liquid swallows with abdominal compression, and 5 multiple rapid swallowing (MRS).Results: DCI was significantly greater during abdominal compression than that of solid swallows (p = 0.025). Compared with liquid swallows, there was a significant decrease in CFV during solid swallows (p = 0.04). DL was significantly greater during solid swallows than that of liquid swallows (p < 0.001) or abdominal compression (p < 0.001). IRP 4s was significantly lower during abdominal compression than that of liquids (p < 0.001) or solid swallows (p = 0.006). All subjects had complete inhibition during MRS and increased DCI after MRS as compared with liquid swallows (p < 0.05).Conclusion: Esophageal provocative test may provide additional utility in performing HRM studies. The data for esophageal provocative tests are distinct from standard liquid swallows.
abstract_unstemmed	Background: Provocative tests were used to provide additional information during performing high resolution manometry (HRM). The study aimed to evaluate whether it is feasible to test esophageal function with different esophageal provocative tests during HRM.Methods: 23 healthy volunteers (9 women; mean age 25 years, range 21–30 years) underwent water-perfused HRM. Each subject received 10 liquid swallows, 10 solid swallows, 10 liquid swallows with abdominal compression, and 5 multiple rapid swallowing (MRS).Results: DCI was significantly greater during abdominal compression than that of solid swallows (p = 0.025). Compared with liquid swallows, there was a significant decrease in CFV during solid swallows (p = 0.04). DL was significantly greater during solid swallows than that of liquid swallows (p < 0.001) or abdominal compression (p < 0.001). IRP 4s was significantly lower during abdominal compression than that of liquids (p < 0.001) or solid swallows (p = 0.006). All subjects had complete inhibition during MRS and increased DCI after MRS as compared with liquid swallows (p < 0.05).Conclusion: Esophageal provocative test may provide additional utility in performing HRM studies. The data for esophageal provocative tests are distinct from standard liquid swallows.
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title_short	Assessment of esophageal function using provocative tests during high resolution manometry: A single-center experience
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author2	Lei, Wei-Yi Hung, Jui-Sheng Liu, Tso-Tsai Yi, Chih-Hsun Chen, Chien-Lin
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doi_str	10.1016/j.jfma.2018.04.010
up_date	2024-07-06T21:10:35.645Z
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