Monolithic glass suspended microchannel resonators for enhanced mass sensing of liquids

Suspended microchannel resonators (SMRs) have been recently developed as highly sensitive platforms to study bacteria, cell populations, antibiotic resistance and other micron-sized analytes. Unfortunately, the time-consuming and challenging fabrication process represents the main drawback for the i...
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Gespeichert in:

Autor*in:	Calmo, Roberta [verfasserIn] Lovera, Andrea [verfasserIn] Stassi, Stefano [verfasserIn] Chiadò, Alessandro [verfasserIn] Scaiola, Davide [verfasserIn] Bosco, Francesca [verfasserIn] Ricciardi, Carlo [verfasserIn]

Format:	E-Artikel
Sprache:	Englisch

Erschienen:	2018

Schlagwörter:	Suspended microchannel resonator Liquid density Femtosecond laser Mass sensing Microfluidics Microbial load

Übergeordnetes Werk:	Enthalten in: Sensors and actuators / B - Amsterdam [u.a.] : Elsevier Science, 1990, 283, Seite 298-303
Übergeordnetes Werk:	volume:283 ; pages:298-303

DOI / URN:	10.1016/j.snb.2018.12.019

Katalog-ID:	ELV001446592

Internformat


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520			\|a Suspended microchannel resonators (SMRs) have been recently developed as highly sensitive platforms to study bacteria, cell populations, antibiotic resistance and other micron-sized analytes. Unfortunately, the time-consuming and challenging fabrication process represents the main drawback for the implementation of these platforms as new point-of-care devices. In this work, we show that femtosecond laser direct writing can be successfully implemented as a rapid and cost-effective 3D fabrication process able to define the suspended resonant structure and the embedded microfluidic channel in one-step, only. Furthermore, the use of a fused silica substrate guarantees a totally transparent resonator, a useful property in view of adding optical analyses to the mechanical one. The resonance properties of the fabricated SMRs were accurately characterized in terms of frequency, quality factor and Allan deviation, in different working conditions. The monolithic glass SMR is able to analyze with high precision liquids with different mass density, thanks to a density resolution (1.04·10−3 kg/m3) that is the highest among SMRs and microcapillaries used for this purpose. Finally, the effective biosensing capability is demonstrated by evaluating the microbial load of aqueous solutions containing different concentrations of P. fluorescens.
650		4	\|a Suspended microchannel resonator
650		4	\|a Liquid density
650		4	\|a Femtosecond laser
650		4	\|a Mass sensing
650		4	\|a Microfluidics
650		4	\|a Microbial load
700	1		\|a Lovera, Andrea \|e verfasserin \|4 aut
700	1		\|a Stassi, Stefano \|e verfasserin \|0 (orcid)0000-0002-1134-7224 \|4 aut
700	1		\|a Chiadò, Alessandro \|e verfasserin \|4 aut
700	1		\|a Scaiola, Davide \|e verfasserin \|4 aut
700	1		\|a Bosco, Francesca \|e verfasserin \|4 aut
700	1		\|a Ricciardi, Carlo \|e verfasserin \|0 (orcid)0000-0002-4703-7949 \|4 aut
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Indexfelder

author_variant	r c rc a l al s s ss a c ac d s ds f b fb c r cr
matchkey_str	article:09254005:2018----::ooihclssseddircanleoaosoehne
hierarchy_sort_str	2018
bklnumber	50.22 35.07
publishDate	2018
allfields	10.1016/j.snb.2018.12.019 doi (DE-627)ELV001446592 (ELSEVIER)S0925-4005(18)32138-5 DE-627 ger DE-627 rda eng 530 620 DE-600 50.22 bkl 35.07 bkl Calmo, Roberta verfasserin aut Monolithic glass suspended microchannel resonators for enhanced mass sensing of liquids 2018 nicht spezifiziert zzz rdacontent Computermedien c rdamedia Online-Ressource cr rdacarrier Suspended microchannel resonators (SMRs) have been recently developed as highly sensitive platforms to study bacteria, cell populations, antibiotic resistance and other micron-sized analytes. Unfortunately, the time-consuming and challenging fabrication process represents the main drawback for the implementation of these platforms as new point-of-care devices. In this work, we show that femtosecond laser direct writing can be successfully implemented as a rapid and cost-effective 3D fabrication process able to define the suspended resonant structure and the embedded microfluidic channel in one-step, only. Furthermore, the use of a fused silica substrate guarantees a totally transparent resonator, a useful property in view of adding optical analyses to the mechanical one. The resonance properties of the fabricated SMRs were accurately characterized in terms of frequency, quality factor and Allan deviation, in different working conditions. The monolithic glass SMR is able to analyze with high precision liquids with different mass density, thanks to a density resolution (1.04·10−3 kg/m3) that is the highest among SMRs and microcapillaries used for this purpose. Finally, the effective biosensing capability is demonstrated by evaluating the microbial load of aqueous solutions containing different concentrations of P. fluorescens. Suspended microchannel resonator Liquid density Femtosecond laser Mass sensing Microfluidics Microbial load Lovera, Andrea verfasserin aut Stassi, Stefano verfasserin (orcid)0000-0002-1134-7224 aut Chiadò, Alessandro verfasserin aut Scaiola, Davide verfasserin aut Bosco, Francesca verfasserin aut Ricciardi, Carlo verfasserin (orcid)0000-0002-4703-7949 aut Enthalten in Sensors and actuators <Lausanne> / B Amsterdam [u.a.] : Elsevier Science, 1990 283, Seite 298-303 Online-Ressource (DE-627)306710358 (DE-600)1500731-5 (DE-576)082435855 0925-4005 nnns volume:283 pages:298-303 GBV_USEFLAG_U SYSFLAG_U GBV_ELV SSG-OLC-PHA GBV_ILN_20 GBV_ILN_22 GBV_ILN_23 GBV_ILN_24 GBV_ILN_31 GBV_ILN_32 GBV_ILN_40 GBV_ILN_60 GBV_ILN_62 GBV_ILN_63 GBV_ILN_65 GBV_ILN_69 GBV_ILN_70 GBV_ILN_73 GBV_ILN_74 GBV_ILN_90 GBV_ILN_95 GBV_ILN_100 GBV_ILN_101 GBV_ILN_105 GBV_ILN_110 GBV_ILN_150 GBV_ILN_151 GBV_ILN_224 GBV_ILN_370 GBV_ILN_602 GBV_ILN_702 GBV_ILN_2003 GBV_ILN_2004 GBV_ILN_2005 GBV_ILN_2011 GBV_ILN_2014 GBV_ILN_2015 GBV_ILN_2020 GBV_ILN_2021 GBV_ILN_2025 GBV_ILN_2027 GBV_ILN_2034 GBV_ILN_2038 GBV_ILN_2044 GBV_ILN_2048 GBV_ILN_2049 GBV_ILN_2050 GBV_ILN_2056 GBV_ILN_2059 GBV_ILN_2061 GBV_ILN_2064 GBV_ILN_2065 GBV_ILN_2068 GBV_ILN_2111 GBV_ILN_2112 GBV_ILN_2113 GBV_ILN_2118 GBV_ILN_2122 GBV_ILN_2129 GBV_ILN_2143 GBV_ILN_2147 GBV_ILN_2148 GBV_ILN_2152 GBV_ILN_2153 GBV_ILN_2190 GBV_ILN_2336 GBV_ILN_2507 GBV_ILN_2522 GBV_ILN_4035 GBV_ILN_4037 GBV_ILN_4112 GBV_ILN_4125 GBV_ILN_4126 GBV_ILN_4242 GBV_ILN_4251 GBV_ILN_4305 GBV_ILN_4313 GBV_ILN_4323 GBV_ILN_4324 GBV_ILN_4326 GBV_ILN_4333 GBV_ILN_4334 GBV_ILN_4335 GBV_ILN_4338 GBV_ILN_4393 50.22 Sensorik 35.07 Chemisches Labor chemische Methoden AR 283 298-303
spelling	10.1016/j.snb.2018.12.019 doi (DE-627)ELV001446592 (ELSEVIER)S0925-4005(18)32138-5 DE-627 ger DE-627 rda eng 530 620 DE-600 50.22 bkl 35.07 bkl Calmo, Roberta verfasserin aut Monolithic glass suspended microchannel resonators for enhanced mass sensing of liquids 2018 nicht spezifiziert zzz rdacontent Computermedien c rdamedia Online-Ressource cr rdacarrier Suspended microchannel resonators (SMRs) have been recently developed as highly sensitive platforms to study bacteria, cell populations, antibiotic resistance and other micron-sized analytes. Unfortunately, the time-consuming and challenging fabrication process represents the main drawback for the implementation of these platforms as new point-of-care devices. In this work, we show that femtosecond laser direct writing can be successfully implemented as a rapid and cost-effective 3D fabrication process able to define the suspended resonant structure and the embedded microfluidic channel in one-step, only. Furthermore, the use of a fused silica substrate guarantees a totally transparent resonator, a useful property in view of adding optical analyses to the mechanical one. The resonance properties of the fabricated SMRs were accurately characterized in terms of frequency, quality factor and Allan deviation, in different working conditions. The monolithic glass SMR is able to analyze with high precision liquids with different mass density, thanks to a density resolution (1.04·10−3 kg/m3) that is the highest among SMRs and microcapillaries used for this purpose. Finally, the effective biosensing capability is demonstrated by evaluating the microbial load of aqueous solutions containing different concentrations of P. fluorescens. Suspended microchannel resonator Liquid density Femtosecond laser Mass sensing Microfluidics Microbial load Lovera, Andrea verfasserin aut Stassi, Stefano verfasserin (orcid)0000-0002-1134-7224 aut Chiadò, Alessandro verfasserin aut Scaiola, Davide verfasserin aut Bosco, Francesca verfasserin aut Ricciardi, Carlo verfasserin (orcid)0000-0002-4703-7949 aut Enthalten in Sensors and actuators <Lausanne> / B Amsterdam [u.a.] : Elsevier Science, 1990 283, Seite 298-303 Online-Ressource (DE-627)306710358 (DE-600)1500731-5 (DE-576)082435855 0925-4005 nnns volume:283 pages:298-303 GBV_USEFLAG_U SYSFLAG_U GBV_ELV SSG-OLC-PHA GBV_ILN_20 GBV_ILN_22 GBV_ILN_23 GBV_ILN_24 GBV_ILN_31 GBV_ILN_32 GBV_ILN_40 GBV_ILN_60 GBV_ILN_62 GBV_ILN_63 GBV_ILN_65 GBV_ILN_69 GBV_ILN_70 GBV_ILN_73 GBV_ILN_74 GBV_ILN_90 GBV_ILN_95 GBV_ILN_100 GBV_ILN_101 GBV_ILN_105 GBV_ILN_110 GBV_ILN_150 GBV_ILN_151 GBV_ILN_224 GBV_ILN_370 GBV_ILN_602 GBV_ILN_702 GBV_ILN_2003 GBV_ILN_2004 GBV_ILN_2005 GBV_ILN_2011 GBV_ILN_2014 GBV_ILN_2015 GBV_ILN_2020 GBV_ILN_2021 GBV_ILN_2025 GBV_ILN_2027 GBV_ILN_2034 GBV_ILN_2038 GBV_ILN_2044 GBV_ILN_2048 GBV_ILN_2049 GBV_ILN_2050 GBV_ILN_2056 GBV_ILN_2059 GBV_ILN_2061 GBV_ILN_2064 GBV_ILN_2065 GBV_ILN_2068 GBV_ILN_2111 GBV_ILN_2112 GBV_ILN_2113 GBV_ILN_2118 GBV_ILN_2122 GBV_ILN_2129 GBV_ILN_2143 GBV_ILN_2147 GBV_ILN_2148 GBV_ILN_2152 GBV_ILN_2153 GBV_ILN_2190 GBV_ILN_2336 GBV_ILN_2507 GBV_ILN_2522 GBV_ILN_4035 GBV_ILN_4037 GBV_ILN_4112 GBV_ILN_4125 GBV_ILN_4126 GBV_ILN_4242 GBV_ILN_4251 GBV_ILN_4305 GBV_ILN_4313 GBV_ILN_4323 GBV_ILN_4324 GBV_ILN_4326 GBV_ILN_4333 GBV_ILN_4334 GBV_ILN_4335 GBV_ILN_4338 GBV_ILN_4393 50.22 Sensorik 35.07 Chemisches Labor chemische Methoden AR 283 298-303
allfields_unstemmed	10.1016/j.snb.2018.12.019 doi (DE-627)ELV001446592 (ELSEVIER)S0925-4005(18)32138-5 DE-627 ger DE-627 rda eng 530 620 DE-600 50.22 bkl 35.07 bkl Calmo, Roberta verfasserin aut Monolithic glass suspended microchannel resonators for enhanced mass sensing of liquids 2018 nicht spezifiziert zzz rdacontent Computermedien c rdamedia Online-Ressource cr rdacarrier Suspended microchannel resonators (SMRs) have been recently developed as highly sensitive platforms to study bacteria, cell populations, antibiotic resistance and other micron-sized analytes. Unfortunately, the time-consuming and challenging fabrication process represents the main drawback for the implementation of these platforms as new point-of-care devices. In this work, we show that femtosecond laser direct writing can be successfully implemented as a rapid and cost-effective 3D fabrication process able to define the suspended resonant structure and the embedded microfluidic channel in one-step, only. Furthermore, the use of a fused silica substrate guarantees a totally transparent resonator, a useful property in view of adding optical analyses to the mechanical one. The resonance properties of the fabricated SMRs were accurately characterized in terms of frequency, quality factor and Allan deviation, in different working conditions. The monolithic glass SMR is able to analyze with high precision liquids with different mass density, thanks to a density resolution (1.04·10−3 kg/m3) that is the highest among SMRs and microcapillaries used for this purpose. Finally, the effective biosensing capability is demonstrated by evaluating the microbial load of aqueous solutions containing different concentrations of P. fluorescens. Suspended microchannel resonator Liquid density Femtosecond laser Mass sensing Microfluidics Microbial load Lovera, Andrea verfasserin aut Stassi, Stefano verfasserin (orcid)0000-0002-1134-7224 aut Chiadò, Alessandro verfasserin aut Scaiola, Davide verfasserin aut Bosco, Francesca verfasserin aut Ricciardi, Carlo verfasserin (orcid)0000-0002-4703-7949 aut Enthalten in Sensors and actuators <Lausanne> / B Amsterdam [u.a.] : Elsevier Science, 1990 283, Seite 298-303 Online-Ressource (DE-627)306710358 (DE-600)1500731-5 (DE-576)082435855 0925-4005 nnns volume:283 pages:298-303 GBV_USEFLAG_U SYSFLAG_U GBV_ELV SSG-OLC-PHA GBV_ILN_20 GBV_ILN_22 GBV_ILN_23 GBV_ILN_24 GBV_ILN_31 GBV_ILN_32 GBV_ILN_40 GBV_ILN_60 GBV_ILN_62 GBV_ILN_63 GBV_ILN_65 GBV_ILN_69 GBV_ILN_70 GBV_ILN_73 GBV_ILN_74 GBV_ILN_90 GBV_ILN_95 GBV_ILN_100 GBV_ILN_101 GBV_ILN_105 GBV_ILN_110 GBV_ILN_150 GBV_ILN_151 GBV_ILN_224 GBV_ILN_370 GBV_ILN_602 GBV_ILN_702 GBV_ILN_2003 GBV_ILN_2004 GBV_ILN_2005 GBV_ILN_2011 GBV_ILN_2014 GBV_ILN_2015 GBV_ILN_2020 GBV_ILN_2021 GBV_ILN_2025 GBV_ILN_2027 GBV_ILN_2034 GBV_ILN_2038 GBV_ILN_2044 GBV_ILN_2048 GBV_ILN_2049 GBV_ILN_2050 GBV_ILN_2056 GBV_ILN_2059 GBV_ILN_2061 GBV_ILN_2064 GBV_ILN_2065 GBV_ILN_2068 GBV_ILN_2111 GBV_ILN_2112 GBV_ILN_2113 GBV_ILN_2118 GBV_ILN_2122 GBV_ILN_2129 GBV_ILN_2143 GBV_ILN_2147 GBV_ILN_2148 GBV_ILN_2152 GBV_ILN_2153 GBV_ILN_2190 GBV_ILN_2336 GBV_ILN_2507 GBV_ILN_2522 GBV_ILN_4035 GBV_ILN_4037 GBV_ILN_4112 GBV_ILN_4125 GBV_ILN_4126 GBV_ILN_4242 GBV_ILN_4251 GBV_ILN_4305 GBV_ILN_4313 GBV_ILN_4323 GBV_ILN_4324 GBV_ILN_4326 GBV_ILN_4333 GBV_ILN_4334 GBV_ILN_4335 GBV_ILN_4338 GBV_ILN_4393 50.22 Sensorik 35.07 Chemisches Labor chemische Methoden AR 283 298-303
allfieldsGer	10.1016/j.snb.2018.12.019 doi (DE-627)ELV001446592 (ELSEVIER)S0925-4005(18)32138-5 DE-627 ger DE-627 rda eng 530 620 DE-600 50.22 bkl 35.07 bkl Calmo, Roberta verfasserin aut Monolithic glass suspended microchannel resonators for enhanced mass sensing of liquids 2018 nicht spezifiziert zzz rdacontent Computermedien c rdamedia Online-Ressource cr rdacarrier Suspended microchannel resonators (SMRs) have been recently developed as highly sensitive platforms to study bacteria, cell populations, antibiotic resistance and other micron-sized analytes. Unfortunately, the time-consuming and challenging fabrication process represents the main drawback for the implementation of these platforms as new point-of-care devices. In this work, we show that femtosecond laser direct writing can be successfully implemented as a rapid and cost-effective 3D fabrication process able to define the suspended resonant structure and the embedded microfluidic channel in one-step, only. Furthermore, the use of a fused silica substrate guarantees a totally transparent resonator, a useful property in view of adding optical analyses to the mechanical one. The resonance properties of the fabricated SMRs were accurately characterized in terms of frequency, quality factor and Allan deviation, in different working conditions. The monolithic glass SMR is able to analyze with high precision liquids with different mass density, thanks to a density resolution (1.04·10−3 kg/m3) that is the highest among SMRs and microcapillaries used for this purpose. Finally, the effective biosensing capability is demonstrated by evaluating the microbial load of aqueous solutions containing different concentrations of P. fluorescens. Suspended microchannel resonator Liquid density Femtosecond laser Mass sensing Microfluidics Microbial load Lovera, Andrea verfasserin aut Stassi, Stefano verfasserin (orcid)0000-0002-1134-7224 aut Chiadò, Alessandro verfasserin aut Scaiola, Davide verfasserin aut Bosco, Francesca verfasserin aut Ricciardi, Carlo verfasserin (orcid)0000-0002-4703-7949 aut Enthalten in Sensors and actuators <Lausanne> / B Amsterdam [u.a.] : Elsevier Science, 1990 283, Seite 298-303 Online-Ressource (DE-627)306710358 (DE-600)1500731-5 (DE-576)082435855 0925-4005 nnns volume:283 pages:298-303 GBV_USEFLAG_U SYSFLAG_U GBV_ELV SSG-OLC-PHA GBV_ILN_20 GBV_ILN_22 GBV_ILN_23 GBV_ILN_24 GBV_ILN_31 GBV_ILN_32 GBV_ILN_40 GBV_ILN_60 GBV_ILN_62 GBV_ILN_63 GBV_ILN_65 GBV_ILN_69 GBV_ILN_70 GBV_ILN_73 GBV_ILN_74 GBV_ILN_90 GBV_ILN_95 GBV_ILN_100 GBV_ILN_101 GBV_ILN_105 GBV_ILN_110 GBV_ILN_150 GBV_ILN_151 GBV_ILN_224 GBV_ILN_370 GBV_ILN_602 GBV_ILN_702 GBV_ILN_2003 GBV_ILN_2004 GBV_ILN_2005 GBV_ILN_2011 GBV_ILN_2014 GBV_ILN_2015 GBV_ILN_2020 GBV_ILN_2021 GBV_ILN_2025 GBV_ILN_2027 GBV_ILN_2034 GBV_ILN_2038 GBV_ILN_2044 GBV_ILN_2048 GBV_ILN_2049 GBV_ILN_2050 GBV_ILN_2056 GBV_ILN_2059 GBV_ILN_2061 GBV_ILN_2064 GBV_ILN_2065 GBV_ILN_2068 GBV_ILN_2111 GBV_ILN_2112 GBV_ILN_2113 GBV_ILN_2118 GBV_ILN_2122 GBV_ILN_2129 GBV_ILN_2143 GBV_ILN_2147 GBV_ILN_2148 GBV_ILN_2152 GBV_ILN_2153 GBV_ILN_2190 GBV_ILN_2336 GBV_ILN_2507 GBV_ILN_2522 GBV_ILN_4035 GBV_ILN_4037 GBV_ILN_4112 GBV_ILN_4125 GBV_ILN_4126 GBV_ILN_4242 GBV_ILN_4251 GBV_ILN_4305 GBV_ILN_4313 GBV_ILN_4323 GBV_ILN_4324 GBV_ILN_4326 GBV_ILN_4333 GBV_ILN_4334 GBV_ILN_4335 GBV_ILN_4338 GBV_ILN_4393 50.22 Sensorik 35.07 Chemisches Labor chemische Methoden AR 283 298-303
allfieldsSound	10.1016/j.snb.2018.12.019 doi (DE-627)ELV001446592 (ELSEVIER)S0925-4005(18)32138-5 DE-627 ger DE-627 rda eng 530 620 DE-600 50.22 bkl 35.07 bkl Calmo, Roberta verfasserin aut Monolithic glass suspended microchannel resonators for enhanced mass sensing of liquids 2018 nicht spezifiziert zzz rdacontent Computermedien c rdamedia Online-Ressource cr rdacarrier Suspended microchannel resonators (SMRs) have been recently developed as highly sensitive platforms to study bacteria, cell populations, antibiotic resistance and other micron-sized analytes. Unfortunately, the time-consuming and challenging fabrication process represents the main drawback for the implementation of these platforms as new point-of-care devices. In this work, we show that femtosecond laser direct writing can be successfully implemented as a rapid and cost-effective 3D fabrication process able to define the suspended resonant structure and the embedded microfluidic channel in one-step, only. Furthermore, the use of a fused silica substrate guarantees a totally transparent resonator, a useful property in view of adding optical analyses to the mechanical one. The resonance properties of the fabricated SMRs were accurately characterized in terms of frequency, quality factor and Allan deviation, in different working conditions. The monolithic glass SMR is able to analyze with high precision liquids with different mass density, thanks to a density resolution (1.04·10−3 kg/m3) that is the highest among SMRs and microcapillaries used for this purpose. Finally, the effective biosensing capability is demonstrated by evaluating the microbial load of aqueous solutions containing different concentrations of P. fluorescens. Suspended microchannel resonator Liquid density Femtosecond laser Mass sensing Microfluidics Microbial load Lovera, Andrea verfasserin aut Stassi, Stefano verfasserin (orcid)0000-0002-1134-7224 aut Chiadò, Alessandro verfasserin aut Scaiola, Davide verfasserin aut Bosco, Francesca verfasserin aut Ricciardi, Carlo verfasserin (orcid)0000-0002-4703-7949 aut Enthalten in Sensors and actuators <Lausanne> / B Amsterdam [u.a.] : Elsevier Science, 1990 283, Seite 298-303 Online-Ressource (DE-627)306710358 (DE-600)1500731-5 (DE-576)082435855 0925-4005 nnns volume:283 pages:298-303 GBV_USEFLAG_U SYSFLAG_U GBV_ELV SSG-OLC-PHA GBV_ILN_20 GBV_ILN_22 GBV_ILN_23 GBV_ILN_24 GBV_ILN_31 GBV_ILN_32 GBV_ILN_40 GBV_ILN_60 GBV_ILN_62 GBV_ILN_63 GBV_ILN_65 GBV_ILN_69 GBV_ILN_70 GBV_ILN_73 GBV_ILN_74 GBV_ILN_90 GBV_ILN_95 GBV_ILN_100 GBV_ILN_101 GBV_ILN_105 GBV_ILN_110 GBV_ILN_150 GBV_ILN_151 GBV_ILN_224 GBV_ILN_370 GBV_ILN_602 GBV_ILN_702 GBV_ILN_2003 GBV_ILN_2004 GBV_ILN_2005 GBV_ILN_2011 GBV_ILN_2014 GBV_ILN_2015 GBV_ILN_2020 GBV_ILN_2021 GBV_ILN_2025 GBV_ILN_2027 GBV_ILN_2034 GBV_ILN_2038 GBV_ILN_2044 GBV_ILN_2048 GBV_ILN_2049 GBV_ILN_2050 GBV_ILN_2056 GBV_ILN_2059 GBV_ILN_2061 GBV_ILN_2064 GBV_ILN_2065 GBV_ILN_2068 GBV_ILN_2111 GBV_ILN_2112 GBV_ILN_2113 GBV_ILN_2118 GBV_ILN_2122 GBV_ILN_2129 GBV_ILN_2143 GBV_ILN_2147 GBV_ILN_2148 GBV_ILN_2152 GBV_ILN_2153 GBV_ILN_2190 GBV_ILN_2336 GBV_ILN_2507 GBV_ILN_2522 GBV_ILN_4035 GBV_ILN_4037 GBV_ILN_4112 GBV_ILN_4125 GBV_ILN_4126 GBV_ILN_4242 GBV_ILN_4251 GBV_ILN_4305 GBV_ILN_4313 GBV_ILN_4323 GBV_ILN_4324 GBV_ILN_4326 GBV_ILN_4333 GBV_ILN_4334 GBV_ILN_4335 GBV_ILN_4338 GBV_ILN_4393 50.22 Sensorik 35.07 Chemisches Labor chemische Methoden AR 283 298-303
language	English
source	Enthalten in Sensors and actuators <Lausanne> / B 283, Seite 298-303 volume:283 pages:298-303
sourceStr	Enthalten in Sensors and actuators <Lausanne> / B 283, Seite 298-303 volume:283 pages:298-303
format_phy_str_mv	Article
bklname	Sensorik Chemisches Labor chemische Methoden
institution	findex.gbv.de
topic_facet	Suspended microchannel resonator Liquid density Femtosecond laser Mass sensing Microfluidics Microbial load
dewey-raw	530
isfreeaccess_bool	false
container_title	Sensors and actuators <Lausanne> / B
authorswithroles_txt_mv	Calmo, Roberta @@aut@@ Lovera, Andrea @@aut@@ Stassi, Stefano @@aut@@ Chiadò, Alessandro @@aut@@ Scaiola, Davide @@aut@@ Bosco, Francesca @@aut@@ Ricciardi, Carlo @@aut@@
publishDateDaySort_date	2018-01-01T00:00:00Z
hierarchy_top_id	306710358
dewey-sort	3530
id	ELV001446592
language_de	englisch
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author	Calmo, Roberta
spellingShingle	Calmo, Roberta ddc 530 bkl 50.22 bkl 35.07 misc Suspended microchannel resonator misc Liquid density misc Femtosecond laser misc Mass sensing misc Microfluidics misc Microbial load Monolithic glass suspended microchannel resonators for enhanced mass sensing of liquids
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topic_title	530 620 DE-600 50.22 bkl 35.07 bkl Monolithic glass suspended microchannel resonators for enhanced mass sensing of liquids Suspended microchannel resonator Liquid density Femtosecond laser Mass sensing Microfluidics Microbial load
topic	ddc 530 bkl 50.22 bkl 35.07 misc Suspended microchannel resonator misc Liquid density misc Femtosecond laser misc Mass sensing misc Microfluidics misc Microbial load
topic_unstemmed	ddc 530 bkl 50.22 bkl 35.07 misc Suspended microchannel resonator misc Liquid density misc Femtosecond laser misc Mass sensing misc Microfluidics misc Microbial load
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title	Monolithic glass suspended microchannel resonators for enhanced mass sensing of liquids
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title_full	Monolithic glass suspended microchannel resonators for enhanced mass sensing of liquids
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title_sort	monolithic glass suspended microchannel resonators for enhanced mass sensing of liquids
title_auth	Monolithic glass suspended microchannel resonators for enhanced mass sensing of liquids
abstract	Suspended microchannel resonators (SMRs) have been recently developed as highly sensitive platforms to study bacteria, cell populations, antibiotic resistance and other micron-sized analytes. Unfortunately, the time-consuming and challenging fabrication process represents the main drawback for the implementation of these platforms as new point-of-care devices. In this work, we show that femtosecond laser direct writing can be successfully implemented as a rapid and cost-effective 3D fabrication process able to define the suspended resonant structure and the embedded microfluidic channel in one-step, only. Furthermore, the use of a fused silica substrate guarantees a totally transparent resonator, a useful property in view of adding optical analyses to the mechanical one. The resonance properties of the fabricated SMRs were accurately characterized in terms of frequency, quality factor and Allan deviation, in different working conditions. The monolithic glass SMR is able to analyze with high precision liquids with different mass density, thanks to a density resolution (1.04·10−3 kg/m3) that is the highest among SMRs and microcapillaries used for this purpose. Finally, the effective biosensing capability is demonstrated by evaluating the microbial load of aqueous solutions containing different concentrations of P. fluorescens.
abstractGer	Suspended microchannel resonators (SMRs) have been recently developed as highly sensitive platforms to study bacteria, cell populations, antibiotic resistance and other micron-sized analytes. Unfortunately, the time-consuming and challenging fabrication process represents the main drawback for the implementation of these platforms as new point-of-care devices. In this work, we show that femtosecond laser direct writing can be successfully implemented as a rapid and cost-effective 3D fabrication process able to define the suspended resonant structure and the embedded microfluidic channel in one-step, only. Furthermore, the use of a fused silica substrate guarantees a totally transparent resonator, a useful property in view of adding optical analyses to the mechanical one. The resonance properties of the fabricated SMRs were accurately characterized in terms of frequency, quality factor and Allan deviation, in different working conditions. The monolithic glass SMR is able to analyze with high precision liquids with different mass density, thanks to a density resolution (1.04·10−3 kg/m3) that is the highest among SMRs and microcapillaries used for this purpose. Finally, the effective biosensing capability is demonstrated by evaluating the microbial load of aqueous solutions containing different concentrations of P. fluorescens.
abstract_unstemmed	Suspended microchannel resonators (SMRs) have been recently developed as highly sensitive platforms to study bacteria, cell populations, antibiotic resistance and other micron-sized analytes. Unfortunately, the time-consuming and challenging fabrication process represents the main drawback for the implementation of these platforms as new point-of-care devices. In this work, we show that femtosecond laser direct writing can be successfully implemented as a rapid and cost-effective 3D fabrication process able to define the suspended resonant structure and the embedded microfluidic channel in one-step, only. Furthermore, the use of a fused silica substrate guarantees a totally transparent resonator, a useful property in view of adding optical analyses to the mechanical one. The resonance properties of the fabricated SMRs were accurately characterized in terms of frequency, quality factor and Allan deviation, in different working conditions. The monolithic glass SMR is able to analyze with high precision liquids with different mass density, thanks to a density resolution (1.04·10−3 kg/m3) that is the highest among SMRs and microcapillaries used for this purpose. Finally, the effective biosensing capability is demonstrated by evaluating the microbial load of aqueous solutions containing different concentrations of P. fluorescens.
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title_short	Monolithic glass suspended microchannel resonators for enhanced mass sensing of liquids
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author2	Lovera, Andrea Stassi, Stefano Chiadò, Alessandro Scaiola, Davide Bosco, Francesca Ricciardi, Carlo
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Monolithic glass suspended microchannel resonators for enhanced mass sensing of liquids

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