A bipolar electrochemical sensor with square wave excitation and ECL readout

We report a sensor platform based on a closed bipolar electrochemical circuit employing electrochemiluminescence detection and square-wave excitation that allows signal averaging to achieve high sensitivity. The cell is comprised of a bipolar electrode fabricated using photolithography that spans se...
Ausführliche Beschreibung

Gespeichert in:

Autor*in:	Yu, Songyan [verfasserIn] Mehrgardi, Masoud [verfasserIn] Shannon, Curtis [verfasserIn]

Format:	E-Artikel
Sprache:	Englisch

Erschienen:	2018

Schlagwörter:	Bipolar electrochemistry Electrochemiluminescence Square-wave amperometry

Übergeordnetes Werk:	Enthalten in: Electrochemistry communications - Amsterdam [u.a.] : Elsevier Science, 1999, 88, Seite 24-28
Übergeordnetes Werk:	volume:88 ; pages:24-28

DOI / URN:	10.1016/j.elecom.2018.01.013

Katalog-ID:	ELV001921681

Internformat


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100	1		\|a Yu, Songyan \|e verfasserin \|4 aut
245	1	0	\|a A bipolar electrochemical sensor with square wave excitation and ECL readout
264		1	\|c 2018
336			\|a nicht spezifiziert \|b zzz \|2 rdacontent
337			\|a Computermedien \|b c \|2 rdamedia
338			\|a Online-Ressource \|b cr \|2 rdacarrier
520			\|a We report a sensor platform based on a closed bipolar electrochemical circuit employing electrochemiluminescence detection and square-wave excitation that allows signal averaging to achieve high sensitivity. The cell is comprised of a bipolar electrode fabricated using photolithography that spans sensing and reporting compartments constructed using a 3D printer. The square-wave technique allows an electroactive analyte to be regenerated by applying a reverse potential, thus allowing significant S/N gains by accumulating ECL signals over multiple measure-regenerate cycles. The working principles of the SW-BPE sensor were demonstrated using Fe(CN)6 3− as a representative analyte. Using DNA self-assembled monolayers as a model for the electrochemical proximity assay co-developed in our laboratories, we demonstrate the ability to detect ca. 300 fmol/cm2 of MB-conjugated DNA. The square wave ECL sensor described herein is capable of detecting a wide variety of analytes over broad concentration ranges, and shows great promise for a variety of analytical applications.
650		4	\|a Bipolar electrochemistry
650		4	\|a Electrochemiluminescence
650		4	\|a Square-wave amperometry
700	1		\|a Mehrgardi, Masoud \|e verfasserin \|4 aut
700	1		\|a Shannon, Curtis \|e verfasserin \|4 aut
773	0	8	\|i Enthalten in \|t Electrochemistry communications \|d Amsterdam [u.a.] : Elsevier Science, 1999 \|g 88, Seite 24-28 \|h Online-Ressource \|w (DE-627)324486073 \|w (DE-600)2027290-X \|w (DE-576)259272019 \|x 1873-1902 \|7 nnns
773	1	8	\|g volume:88 \|g pages:24-28
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912			\|a GBV_ILN_60
912			\|a GBV_ILN_62
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912			\|a GBV_ILN_90
912			\|a GBV_ILN_95
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912			\|a GBV_ILN_101
912			\|a GBV_ILN_105
912			\|a GBV_ILN_110
912			\|a GBV_ILN_150
912			\|a GBV_ILN_151
912			\|a GBV_ILN_165
912			\|a GBV_ILN_187
912			\|a GBV_ILN_213
912			\|a GBV_ILN_224
912			\|a GBV_ILN_230
912			\|a GBV_ILN_370
912			\|a GBV_ILN_602
912			\|a GBV_ILN_702
912			\|a GBV_ILN_2003
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912			\|a GBV_ILN_2044
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912			\|a GBV_ILN_2056
912			\|a GBV_ILN_2059
912			\|a GBV_ILN_2061
912			\|a GBV_ILN_2064
912			\|a GBV_ILN_2065
912			\|a GBV_ILN_2068
912			\|a GBV_ILN_2106
912			\|a GBV_ILN_2111
912			\|a GBV_ILN_2112
912			\|a GBV_ILN_2113
912			\|a GBV_ILN_2118
912			\|a GBV_ILN_2122
912			\|a GBV_ILN_2129
912			\|a GBV_ILN_2143
912			\|a GBV_ILN_2147
912			\|a GBV_ILN_2148
912			\|a GBV_ILN_2152
912			\|a GBV_ILN_2153
912			\|a GBV_ILN_2190
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912			\|a GBV_ILN_2336
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912			\|a GBV_ILN_2507
912			\|a GBV_ILN_2522
912			\|a GBV_ILN_4035
912			\|a GBV_ILN_4037
912			\|a GBV_ILN_4112
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912			\|a GBV_ILN_4335
912			\|a GBV_ILN_4338
912			\|a GBV_ILN_4393
912			\|a GBV_ILN_4700
936	b	k	\|a 35.14 \|j Elektrochemie
951			\|a AR
952			\|d 88 \|h 24-28

Indexfelder

author_variant	s y sy m m mm c s cs
matchkey_str	article:18731902:2018----::bplrlcrceiasnowtsurwvect
hierarchy_sort_str	2018
bklnumber	35.14
publishDate	2018
allfields	10.1016/j.elecom.2018.01.013 doi (DE-627)ELV001921681 (ELSEVIER)S1388-2481(18)30013-4 DE-627 ger DE-627 rda eng 540 DE-600 35.14 bkl Yu, Songyan verfasserin aut A bipolar electrochemical sensor with square wave excitation and ECL readout 2018 nicht spezifiziert zzz rdacontent Computermedien c rdamedia Online-Ressource cr rdacarrier We report a sensor platform based on a closed bipolar electrochemical circuit employing electrochemiluminescence detection and square-wave excitation that allows signal averaging to achieve high sensitivity. The cell is comprised of a bipolar electrode fabricated using photolithography that spans sensing and reporting compartments constructed using a 3D printer. The square-wave technique allows an electroactive analyte to be regenerated by applying a reverse potential, thus allowing significant S/N gains by accumulating ECL signals over multiple measure-regenerate cycles. The working principles of the SW-BPE sensor were demonstrated using Fe(CN)6 3− as a representative analyte. Using DNA self-assembled monolayers as a model for the electrochemical proximity assay co-developed in our laboratories, we demonstrate the ability to detect ca. 300 fmol/cm2 of MB-conjugated DNA. The square wave ECL sensor described herein is capable of detecting a wide variety of analytes over broad concentration ranges, and shows great promise for a variety of analytical applications. Bipolar electrochemistry Electrochemiluminescence Square-wave amperometry Mehrgardi, Masoud verfasserin aut Shannon, Curtis verfasserin aut Enthalten in Electrochemistry communications Amsterdam [u.a.] : Elsevier Science, 1999 88, Seite 24-28 Online-Ressource (DE-627)324486073 (DE-600)2027290-X (DE-576)259272019 1873-1902 nnns volume:88 pages:24-28 GBV_USEFLAG_U SYSFLAG_U GBV_ELV GBV_ILN_20 GBV_ILN_22 GBV_ILN_23 GBV_ILN_24 GBV_ILN_31 GBV_ILN_32 GBV_ILN_40 GBV_ILN_60 GBV_ILN_62 GBV_ILN_63 GBV_ILN_65 GBV_ILN_69 GBV_ILN_70 GBV_ILN_73 GBV_ILN_74 GBV_ILN_90 GBV_ILN_95 GBV_ILN_100 GBV_ILN_101 GBV_ILN_105 GBV_ILN_110 GBV_ILN_150 GBV_ILN_151 GBV_ILN_165 GBV_ILN_187 GBV_ILN_213 GBV_ILN_224 GBV_ILN_230 GBV_ILN_370 GBV_ILN_602 GBV_ILN_702 GBV_ILN_2003 GBV_ILN_2004 GBV_ILN_2005 GBV_ILN_2007 GBV_ILN_2009 GBV_ILN_2011 GBV_ILN_2014 GBV_ILN_2015 GBV_ILN_2020 GBV_ILN_2021 GBV_ILN_2025 GBV_ILN_2027 GBV_ILN_2034 GBV_ILN_2038 GBV_ILN_2044 GBV_ILN_2048 GBV_ILN_2049 GBV_ILN_2050 GBV_ILN_2056 GBV_ILN_2059 GBV_ILN_2061 GBV_ILN_2064 GBV_ILN_2065 GBV_ILN_2068 GBV_ILN_2106 GBV_ILN_2111 GBV_ILN_2112 GBV_ILN_2113 GBV_ILN_2118 GBV_ILN_2122 GBV_ILN_2129 GBV_ILN_2143 GBV_ILN_2147 GBV_ILN_2148 GBV_ILN_2152 GBV_ILN_2153 GBV_ILN_2190 GBV_ILN_2232 GBV_ILN_2336 GBV_ILN_2470 GBV_ILN_2507 GBV_ILN_2522 GBV_ILN_4035 GBV_ILN_4037 GBV_ILN_4112 GBV_ILN_4125 GBV_ILN_4126 GBV_ILN_4242 GBV_ILN_4251 GBV_ILN_4305 GBV_ILN_4313 GBV_ILN_4322 GBV_ILN_4323 GBV_ILN_4324 GBV_ILN_4326 GBV_ILN_4333 GBV_ILN_4334 GBV_ILN_4335 GBV_ILN_4338 GBV_ILN_4393 GBV_ILN_4700 35.14 Elektrochemie AR 88 24-28
spelling	10.1016/j.elecom.2018.01.013 doi (DE-627)ELV001921681 (ELSEVIER)S1388-2481(18)30013-4 DE-627 ger DE-627 rda eng 540 DE-600 35.14 bkl Yu, Songyan verfasserin aut A bipolar electrochemical sensor with square wave excitation and ECL readout 2018 nicht spezifiziert zzz rdacontent Computermedien c rdamedia Online-Ressource cr rdacarrier We report a sensor platform based on a closed bipolar electrochemical circuit employing electrochemiluminescence detection and square-wave excitation that allows signal averaging to achieve high sensitivity. The cell is comprised of a bipolar electrode fabricated using photolithography that spans sensing and reporting compartments constructed using a 3D printer. The square-wave technique allows an electroactive analyte to be regenerated by applying a reverse potential, thus allowing significant S/N gains by accumulating ECL signals over multiple measure-regenerate cycles. The working principles of the SW-BPE sensor were demonstrated using Fe(CN)6 3− as a representative analyte. Using DNA self-assembled monolayers as a model for the electrochemical proximity assay co-developed in our laboratories, we demonstrate the ability to detect ca. 300 fmol/cm2 of MB-conjugated DNA. The square wave ECL sensor described herein is capable of detecting a wide variety of analytes over broad concentration ranges, and shows great promise for a variety of analytical applications. Bipolar electrochemistry Electrochemiluminescence Square-wave amperometry Mehrgardi, Masoud verfasserin aut Shannon, Curtis verfasserin aut Enthalten in Electrochemistry communications Amsterdam [u.a.] : Elsevier Science, 1999 88, Seite 24-28 Online-Ressource (DE-627)324486073 (DE-600)2027290-X (DE-576)259272019 1873-1902 nnns volume:88 pages:24-28 GBV_USEFLAG_U SYSFLAG_U GBV_ELV GBV_ILN_20 GBV_ILN_22 GBV_ILN_23 GBV_ILN_24 GBV_ILN_31 GBV_ILN_32 GBV_ILN_40 GBV_ILN_60 GBV_ILN_62 GBV_ILN_63 GBV_ILN_65 GBV_ILN_69 GBV_ILN_70 GBV_ILN_73 GBV_ILN_74 GBV_ILN_90 GBV_ILN_95 GBV_ILN_100 GBV_ILN_101 GBV_ILN_105 GBV_ILN_110 GBV_ILN_150 GBV_ILN_151 GBV_ILN_165 GBV_ILN_187 GBV_ILN_213 GBV_ILN_224 GBV_ILN_230 GBV_ILN_370 GBV_ILN_602 GBV_ILN_702 GBV_ILN_2003 GBV_ILN_2004 GBV_ILN_2005 GBV_ILN_2007 GBV_ILN_2009 GBV_ILN_2011 GBV_ILN_2014 GBV_ILN_2015 GBV_ILN_2020 GBV_ILN_2021 GBV_ILN_2025 GBV_ILN_2027 GBV_ILN_2034 GBV_ILN_2038 GBV_ILN_2044 GBV_ILN_2048 GBV_ILN_2049 GBV_ILN_2050 GBV_ILN_2056 GBV_ILN_2059 GBV_ILN_2061 GBV_ILN_2064 GBV_ILN_2065 GBV_ILN_2068 GBV_ILN_2106 GBV_ILN_2111 GBV_ILN_2112 GBV_ILN_2113 GBV_ILN_2118 GBV_ILN_2122 GBV_ILN_2129 GBV_ILN_2143 GBV_ILN_2147 GBV_ILN_2148 GBV_ILN_2152 GBV_ILN_2153 GBV_ILN_2190 GBV_ILN_2232 GBV_ILN_2336 GBV_ILN_2470 GBV_ILN_2507 GBV_ILN_2522 GBV_ILN_4035 GBV_ILN_4037 GBV_ILN_4112 GBV_ILN_4125 GBV_ILN_4126 GBV_ILN_4242 GBV_ILN_4251 GBV_ILN_4305 GBV_ILN_4313 GBV_ILN_4322 GBV_ILN_4323 GBV_ILN_4324 GBV_ILN_4326 GBV_ILN_4333 GBV_ILN_4334 GBV_ILN_4335 GBV_ILN_4338 GBV_ILN_4393 GBV_ILN_4700 35.14 Elektrochemie AR 88 24-28
allfields_unstemmed	10.1016/j.elecom.2018.01.013 doi (DE-627)ELV001921681 (ELSEVIER)S1388-2481(18)30013-4 DE-627 ger DE-627 rda eng 540 DE-600 35.14 bkl Yu, Songyan verfasserin aut A bipolar electrochemical sensor with square wave excitation and ECL readout 2018 nicht spezifiziert zzz rdacontent Computermedien c rdamedia Online-Ressource cr rdacarrier We report a sensor platform based on a closed bipolar electrochemical circuit employing electrochemiluminescence detection and square-wave excitation that allows signal averaging to achieve high sensitivity. The cell is comprised of a bipolar electrode fabricated using photolithography that spans sensing and reporting compartments constructed using a 3D printer. The square-wave technique allows an electroactive analyte to be regenerated by applying a reverse potential, thus allowing significant S/N gains by accumulating ECL signals over multiple measure-regenerate cycles. The working principles of the SW-BPE sensor were demonstrated using Fe(CN)6 3− as a representative analyte. Using DNA self-assembled monolayers as a model for the electrochemical proximity assay co-developed in our laboratories, we demonstrate the ability to detect ca. 300 fmol/cm2 of MB-conjugated DNA. The square wave ECL sensor described herein is capable of detecting a wide variety of analytes over broad concentration ranges, and shows great promise for a variety of analytical applications. Bipolar electrochemistry Electrochemiluminescence Square-wave amperometry Mehrgardi, Masoud verfasserin aut Shannon, Curtis verfasserin aut Enthalten in Electrochemistry communications Amsterdam [u.a.] : Elsevier Science, 1999 88, Seite 24-28 Online-Ressource (DE-627)324486073 (DE-600)2027290-X (DE-576)259272019 1873-1902 nnns volume:88 pages:24-28 GBV_USEFLAG_U SYSFLAG_U GBV_ELV GBV_ILN_20 GBV_ILN_22 GBV_ILN_23 GBV_ILN_24 GBV_ILN_31 GBV_ILN_32 GBV_ILN_40 GBV_ILN_60 GBV_ILN_62 GBV_ILN_63 GBV_ILN_65 GBV_ILN_69 GBV_ILN_70 GBV_ILN_73 GBV_ILN_74 GBV_ILN_90 GBV_ILN_95 GBV_ILN_100 GBV_ILN_101 GBV_ILN_105 GBV_ILN_110 GBV_ILN_150 GBV_ILN_151 GBV_ILN_165 GBV_ILN_187 GBV_ILN_213 GBV_ILN_224 GBV_ILN_230 GBV_ILN_370 GBV_ILN_602 GBV_ILN_702 GBV_ILN_2003 GBV_ILN_2004 GBV_ILN_2005 GBV_ILN_2007 GBV_ILN_2009 GBV_ILN_2011 GBV_ILN_2014 GBV_ILN_2015 GBV_ILN_2020 GBV_ILN_2021 GBV_ILN_2025 GBV_ILN_2027 GBV_ILN_2034 GBV_ILN_2038 GBV_ILN_2044 GBV_ILN_2048 GBV_ILN_2049 GBV_ILN_2050 GBV_ILN_2056 GBV_ILN_2059 GBV_ILN_2061 GBV_ILN_2064 GBV_ILN_2065 GBV_ILN_2068 GBV_ILN_2106 GBV_ILN_2111 GBV_ILN_2112 GBV_ILN_2113 GBV_ILN_2118 GBV_ILN_2122 GBV_ILN_2129 GBV_ILN_2143 GBV_ILN_2147 GBV_ILN_2148 GBV_ILN_2152 GBV_ILN_2153 GBV_ILN_2190 GBV_ILN_2232 GBV_ILN_2336 GBV_ILN_2470 GBV_ILN_2507 GBV_ILN_2522 GBV_ILN_4035 GBV_ILN_4037 GBV_ILN_4112 GBV_ILN_4125 GBV_ILN_4126 GBV_ILN_4242 GBV_ILN_4251 GBV_ILN_4305 GBV_ILN_4313 GBV_ILN_4322 GBV_ILN_4323 GBV_ILN_4324 GBV_ILN_4326 GBV_ILN_4333 GBV_ILN_4334 GBV_ILN_4335 GBV_ILN_4338 GBV_ILN_4393 GBV_ILN_4700 35.14 Elektrochemie AR 88 24-28
allfieldsGer	10.1016/j.elecom.2018.01.013 doi (DE-627)ELV001921681 (ELSEVIER)S1388-2481(18)30013-4 DE-627 ger DE-627 rda eng 540 DE-600 35.14 bkl Yu, Songyan verfasserin aut A bipolar electrochemical sensor with square wave excitation and ECL readout 2018 nicht spezifiziert zzz rdacontent Computermedien c rdamedia Online-Ressource cr rdacarrier We report a sensor platform based on a closed bipolar electrochemical circuit employing electrochemiluminescence detection and square-wave excitation that allows signal averaging to achieve high sensitivity. The cell is comprised of a bipolar electrode fabricated using photolithography that spans sensing and reporting compartments constructed using a 3D printer. The square-wave technique allows an electroactive analyte to be regenerated by applying a reverse potential, thus allowing significant S/N gains by accumulating ECL signals over multiple measure-regenerate cycles. The working principles of the SW-BPE sensor were demonstrated using Fe(CN)6 3− as a representative analyte. Using DNA self-assembled monolayers as a model for the electrochemical proximity assay co-developed in our laboratories, we demonstrate the ability to detect ca. 300 fmol/cm2 of MB-conjugated DNA. The square wave ECL sensor described herein is capable of detecting a wide variety of analytes over broad concentration ranges, and shows great promise for a variety of analytical applications. Bipolar electrochemistry Electrochemiluminescence Square-wave amperometry Mehrgardi, Masoud verfasserin aut Shannon, Curtis verfasserin aut Enthalten in Electrochemistry communications Amsterdam [u.a.] : Elsevier Science, 1999 88, Seite 24-28 Online-Ressource (DE-627)324486073 (DE-600)2027290-X (DE-576)259272019 1873-1902 nnns volume:88 pages:24-28 GBV_USEFLAG_U SYSFLAG_U GBV_ELV GBV_ILN_20 GBV_ILN_22 GBV_ILN_23 GBV_ILN_24 GBV_ILN_31 GBV_ILN_32 GBV_ILN_40 GBV_ILN_60 GBV_ILN_62 GBV_ILN_63 GBV_ILN_65 GBV_ILN_69 GBV_ILN_70 GBV_ILN_73 GBV_ILN_74 GBV_ILN_90 GBV_ILN_95 GBV_ILN_100 GBV_ILN_101 GBV_ILN_105 GBV_ILN_110 GBV_ILN_150 GBV_ILN_151 GBV_ILN_165 GBV_ILN_187 GBV_ILN_213 GBV_ILN_224 GBV_ILN_230 GBV_ILN_370 GBV_ILN_602 GBV_ILN_702 GBV_ILN_2003 GBV_ILN_2004 GBV_ILN_2005 GBV_ILN_2007 GBV_ILN_2009 GBV_ILN_2011 GBV_ILN_2014 GBV_ILN_2015 GBV_ILN_2020 GBV_ILN_2021 GBV_ILN_2025 GBV_ILN_2027 GBV_ILN_2034 GBV_ILN_2038 GBV_ILN_2044 GBV_ILN_2048 GBV_ILN_2049 GBV_ILN_2050 GBV_ILN_2056 GBV_ILN_2059 GBV_ILN_2061 GBV_ILN_2064 GBV_ILN_2065 GBV_ILN_2068 GBV_ILN_2106 GBV_ILN_2111 GBV_ILN_2112 GBV_ILN_2113 GBV_ILN_2118 GBV_ILN_2122 GBV_ILN_2129 GBV_ILN_2143 GBV_ILN_2147 GBV_ILN_2148 GBV_ILN_2152 GBV_ILN_2153 GBV_ILN_2190 GBV_ILN_2232 GBV_ILN_2336 GBV_ILN_2470 GBV_ILN_2507 GBV_ILN_2522 GBV_ILN_4035 GBV_ILN_4037 GBV_ILN_4112 GBV_ILN_4125 GBV_ILN_4126 GBV_ILN_4242 GBV_ILN_4251 GBV_ILN_4305 GBV_ILN_4313 GBV_ILN_4322 GBV_ILN_4323 GBV_ILN_4324 GBV_ILN_4326 GBV_ILN_4333 GBV_ILN_4334 GBV_ILN_4335 GBV_ILN_4338 GBV_ILN_4393 GBV_ILN_4700 35.14 Elektrochemie AR 88 24-28
allfieldsSound	10.1016/j.elecom.2018.01.013 doi (DE-627)ELV001921681 (ELSEVIER)S1388-2481(18)30013-4 DE-627 ger DE-627 rda eng 540 DE-600 35.14 bkl Yu, Songyan verfasserin aut A bipolar electrochemical sensor with square wave excitation and ECL readout 2018 nicht spezifiziert zzz rdacontent Computermedien c rdamedia Online-Ressource cr rdacarrier We report a sensor platform based on a closed bipolar electrochemical circuit employing electrochemiluminescence detection and square-wave excitation that allows signal averaging to achieve high sensitivity. The cell is comprised of a bipolar electrode fabricated using photolithography that spans sensing and reporting compartments constructed using a 3D printer. The square-wave technique allows an electroactive analyte to be regenerated by applying a reverse potential, thus allowing significant S/N gains by accumulating ECL signals over multiple measure-regenerate cycles. The working principles of the SW-BPE sensor were demonstrated using Fe(CN)6 3− as a representative analyte. Using DNA self-assembled monolayers as a model for the electrochemical proximity assay co-developed in our laboratories, we demonstrate the ability to detect ca. 300 fmol/cm2 of MB-conjugated DNA. The square wave ECL sensor described herein is capable of detecting a wide variety of analytes over broad concentration ranges, and shows great promise for a variety of analytical applications. Bipolar electrochemistry Electrochemiluminescence Square-wave amperometry Mehrgardi, Masoud verfasserin aut Shannon, Curtis verfasserin aut Enthalten in Electrochemistry communications Amsterdam [u.a.] : Elsevier Science, 1999 88, Seite 24-28 Online-Ressource (DE-627)324486073 (DE-600)2027290-X (DE-576)259272019 1873-1902 nnns volume:88 pages:24-28 GBV_USEFLAG_U SYSFLAG_U GBV_ELV GBV_ILN_20 GBV_ILN_22 GBV_ILN_23 GBV_ILN_24 GBV_ILN_31 GBV_ILN_32 GBV_ILN_40 GBV_ILN_60 GBV_ILN_62 GBV_ILN_63 GBV_ILN_65 GBV_ILN_69 GBV_ILN_70 GBV_ILN_73 GBV_ILN_74 GBV_ILN_90 GBV_ILN_95 GBV_ILN_100 GBV_ILN_101 GBV_ILN_105 GBV_ILN_110 GBV_ILN_150 GBV_ILN_151 GBV_ILN_165 GBV_ILN_187 GBV_ILN_213 GBV_ILN_224 GBV_ILN_230 GBV_ILN_370 GBV_ILN_602 GBV_ILN_702 GBV_ILN_2003 GBV_ILN_2004 GBV_ILN_2005 GBV_ILN_2007 GBV_ILN_2009 GBV_ILN_2011 GBV_ILN_2014 GBV_ILN_2015 GBV_ILN_2020 GBV_ILN_2021 GBV_ILN_2025 GBV_ILN_2027 GBV_ILN_2034 GBV_ILN_2038 GBV_ILN_2044 GBV_ILN_2048 GBV_ILN_2049 GBV_ILN_2050 GBV_ILN_2056 GBV_ILN_2059 GBV_ILN_2061 GBV_ILN_2064 GBV_ILN_2065 GBV_ILN_2068 GBV_ILN_2106 GBV_ILN_2111 GBV_ILN_2112 GBV_ILN_2113 GBV_ILN_2118 GBV_ILN_2122 GBV_ILN_2129 GBV_ILN_2143 GBV_ILN_2147 GBV_ILN_2148 GBV_ILN_2152 GBV_ILN_2153 GBV_ILN_2190 GBV_ILN_2232 GBV_ILN_2336 GBV_ILN_2470 GBV_ILN_2507 GBV_ILN_2522 GBV_ILN_4035 GBV_ILN_4037 GBV_ILN_4112 GBV_ILN_4125 GBV_ILN_4126 GBV_ILN_4242 GBV_ILN_4251 GBV_ILN_4305 GBV_ILN_4313 GBV_ILN_4322 GBV_ILN_4323 GBV_ILN_4324 GBV_ILN_4326 GBV_ILN_4333 GBV_ILN_4334 GBV_ILN_4335 GBV_ILN_4338 GBV_ILN_4393 GBV_ILN_4700 35.14 Elektrochemie AR 88 24-28
language	English
source	Enthalten in Electrochemistry communications 88, Seite 24-28 volume:88 pages:24-28
sourceStr	Enthalten in Electrochemistry communications 88, Seite 24-28 volume:88 pages:24-28
format_phy_str_mv	Article
bklname	Elektrochemie
institution	findex.gbv.de
topic_facet	Bipolar electrochemistry Electrochemiluminescence Square-wave amperometry
dewey-raw	540
isfreeaccess_bool	false
container_title	Electrochemistry communications
authorswithroles_txt_mv	Yu, Songyan @@aut@@ Mehrgardi, Masoud @@aut@@ Shannon, Curtis @@aut@@
publishDateDaySort_date	2018-01-01T00:00:00Z
hierarchy_top_id	324486073
dewey-sort	3540
id	ELV001921681
language_de	englisch
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author	Yu, Songyan
spellingShingle	Yu, Songyan ddc 540 bkl 35.14 misc Bipolar electrochemistry misc Electrochemiluminescence misc Square-wave amperometry A bipolar electrochemical sensor with square wave excitation and ECL readout
authorStr	Yu, Songyan
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topic_title	540 DE-600 35.14 bkl A bipolar electrochemical sensor with square wave excitation and ECL readout Bipolar electrochemistry Electrochemiluminescence Square-wave amperometry
topic	ddc 540 bkl 35.14 misc Bipolar electrochemistry misc Electrochemiluminescence misc Square-wave amperometry
topic_unstemmed	ddc 540 bkl 35.14 misc Bipolar electrochemistry misc Electrochemiluminescence misc Square-wave amperometry
topic_browse	ddc 540 bkl 35.14 misc Bipolar electrochemistry misc Electrochemiluminescence misc Square-wave amperometry
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title	A bipolar electrochemical sensor with square wave excitation and ECL readout
ctrlnum	(DE-627)ELV001921681 (ELSEVIER)S1388-2481(18)30013-4
title_full	A bipolar electrochemical sensor with square wave excitation and ECL readout
author_sort	Yu, Songyan
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author_browse	Yu, Songyan Mehrgardi, Masoud Shannon, Curtis
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doi_str_mv	10.1016/j.elecom.2018.01.013
dewey-full	540
author2-role	verfasserin
title_sort	a bipolar electrochemical sensor with square wave excitation and ecl readout
title_auth	A bipolar electrochemical sensor with square wave excitation and ECL readout
abstract	We report a sensor platform based on a closed bipolar electrochemical circuit employing electrochemiluminescence detection and square-wave excitation that allows signal averaging to achieve high sensitivity. The cell is comprised of a bipolar electrode fabricated using photolithography that spans sensing and reporting compartments constructed using a 3D printer. The square-wave technique allows an electroactive analyte to be regenerated by applying a reverse potential, thus allowing significant S/N gains by accumulating ECL signals over multiple measure-regenerate cycles. The working principles of the SW-BPE sensor were demonstrated using Fe(CN)6 3− as a representative analyte. Using DNA self-assembled monolayers as a model for the electrochemical proximity assay co-developed in our laboratories, we demonstrate the ability to detect ca. 300 fmol/cm2 of MB-conjugated DNA. The square wave ECL sensor described herein is capable of detecting a wide variety of analytes over broad concentration ranges, and shows great promise for a variety of analytical applications.
abstractGer	We report a sensor platform based on a closed bipolar electrochemical circuit employing electrochemiluminescence detection and square-wave excitation that allows signal averaging to achieve high sensitivity. The cell is comprised of a bipolar electrode fabricated using photolithography that spans sensing and reporting compartments constructed using a 3D printer. The square-wave technique allows an electroactive analyte to be regenerated by applying a reverse potential, thus allowing significant S/N gains by accumulating ECL signals over multiple measure-regenerate cycles. The working principles of the SW-BPE sensor were demonstrated using Fe(CN)6 3− as a representative analyte. Using DNA self-assembled monolayers as a model for the electrochemical proximity assay co-developed in our laboratories, we demonstrate the ability to detect ca. 300 fmol/cm2 of MB-conjugated DNA. The square wave ECL sensor described herein is capable of detecting a wide variety of analytes over broad concentration ranges, and shows great promise for a variety of analytical applications.
abstract_unstemmed	We report a sensor platform based on a closed bipolar electrochemical circuit employing electrochemiluminescence detection and square-wave excitation that allows signal averaging to achieve high sensitivity. The cell is comprised of a bipolar electrode fabricated using photolithography that spans sensing and reporting compartments constructed using a 3D printer. The square-wave technique allows an electroactive analyte to be regenerated by applying a reverse potential, thus allowing significant S/N gains by accumulating ECL signals over multiple measure-regenerate cycles. The working principles of the SW-BPE sensor were demonstrated using Fe(CN)6 3− as a representative analyte. Using DNA self-assembled monolayers as a model for the electrochemical proximity assay co-developed in our laboratories, we demonstrate the ability to detect ca. 300 fmol/cm2 of MB-conjugated DNA. The square wave ECL sensor described herein is capable of detecting a wide variety of analytes over broad concentration ranges, and shows great promise for a variety of analytical applications.
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title_short	A bipolar electrochemical sensor with square wave excitation and ECL readout
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author2	Mehrgardi, Masoud Shannon, Curtis
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doi_str	10.1016/j.elecom.2018.01.013
up_date	2024-07-06T23:01:18.894Z
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A bipolar electrochemical sensor with square wave excitation and ECL readout

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