Acute kidney injury following contrast media administration in the septic patient: A retrospective propensity-matched analysis

Purpose: To determine the risk for acute kidney injury (AKI) attributable to intravenous contrast media (CM) administration in septic patients.Materials and methods: This was a single-center retrospective propensity matched cohort analysis performed in the emergency department (ED) of an academic me...
Ausführliche Beschreibung

Gespeichert in:

Autor*in:	Hinson, Jeremiah S. [verfasserIn] Al Jalbout, Nour [verfasserIn] Ehmann, Michael R. [verfasserIn] Klein, Eili Y. [verfasserIn]

Format:	E-Artikel
Sprache:	Englisch

Erschienen:	2019

Schlagwörter:	Acute kidney injury Sepsis Contrast media Contrast-induced nephropathy

Übergeordnetes Werk:	Enthalten in: Journal of critical care - [Amsterdam] : Elsevier, 1986, 51, Seite 111-116
Übergeordnetes Werk:	volume:51 ; pages:111-116

DOI / URN:	10.1016/j.jcrc.2019.02.003

Katalog-ID:	ELV002291649

Internformat


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245	1	0	\|a Acute kidney injury following contrast media administration in the septic patient: A retrospective propensity-matched analysis
264		1	\|c 2019
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337			\|a Computermedien \|b c \|2 rdamedia
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520			\|a Purpose: To determine the risk for acute kidney injury (AKI) attributable to intravenous contrast media (CM) administration in septic patients.Materials and methods: This was a single-center retrospective propensity matched cohort analysis performed in the emergency department (ED) of an academic medical center. All visits for patients ≥18 years who met sepsis diagnostic criteria and had serum creatinine (SCr) measured both on arrival to the ED and again 48 to 72 h later were included. Of 4171 visits, 1464 patients underwent contrast-enhanced CT (CECT), 976 underwent unenhanced CT and 1731 underwent no CT at all.Results: The primary outcome was incidence of AKI. Logistic regression and between-groups odds ratios with and without propensity-score matching were used to test for an independent association between CM administration and AKI. Incidence of AKI was 7.2%, 9.4% and 9.7% in those who underwent CECT, unenhanced CT and no CT. CM administration was not associated with increased incidence of AKI.Conclusions: Sepsis is a medical emergency proven to benefit from early diagnosis and rapid initiation of treatment, which is often aided by CECT. Our findings argue against withholding CM for fear of precipitating AKI in potentially septic patients.
650		4	\|a Acute kidney injury
650		4	\|a Sepsis
650		4	\|a Contrast media
650		4	\|a Contrast-induced nephropathy
700	1		\|a Al Jalbout, Nour \|e verfasserin \|0 (orcid)0000-0002-9369-0260 \|4 aut
700	1		\|a Ehmann, Michael R. \|e verfasserin \|4 aut
700	1		\|a Klein, Eili Y. \|e verfasserin \|4 aut
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author_variant	j s h js jsh j n a jn jna m r e mr mre e y k ey eyk
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publishDate	2019
allfields	10.1016/j.jcrc.2019.02.003 doi (DE-627)ELV002291649 (ELSEVIER)S0883-9441(18)31518-1 DE-627 ger DE-627 rda eng 610 DE-600 44.69 bkl Hinson, Jeremiah S. verfasserin aut Acute kidney injury following contrast media administration in the septic patient: A retrospective propensity-matched analysis 2019 nicht spezifiziert zzz rdacontent Computermedien c rdamedia Online-Ressource cr rdacarrier Purpose: To determine the risk for acute kidney injury (AKI) attributable to intravenous contrast media (CM) administration in septic patients.Materials and methods: This was a single-center retrospective propensity matched cohort analysis performed in the emergency department (ED) of an academic medical center. All visits for patients ≥18 years who met sepsis diagnostic criteria and had serum creatinine (SCr) measured both on arrival to the ED and again 48 to 72 h later were included. Of 4171 visits, 1464 patients underwent contrast-enhanced CT (CECT), 976 underwent unenhanced CT and 1731 underwent no CT at all.Results: The primary outcome was incidence of AKI. Logistic regression and between-groups odds ratios with and without propensity-score matching were used to test for an independent association between CM administration and AKI. Incidence of AKI was 7.2%, 9.4% and 9.7% in those who underwent CECT, unenhanced CT and no CT. CM administration was not associated with increased incidence of AKI.Conclusions: Sepsis is a medical emergency proven to benefit from early diagnosis and rapid initiation of treatment, which is often aided by CECT. Our findings argue against withholding CM for fear of precipitating AKI in potentially septic patients. Acute kidney injury Sepsis Contrast media Contrast-induced nephropathy Al Jalbout, Nour verfasserin (orcid)0000-0002-9369-0260 aut Ehmann, Michael R. verfasserin aut Klein, Eili Y. verfasserin aut Enthalten in Journal of critical care [Amsterdam] : Elsevier, 1986 51, Seite 111-116 Online-Ressource (DE-627)326646167 (DE-600)2041640-4 (DE-576)096188820 1557-8615 nnns volume:51 pages:111-116 GBV_USEFLAG_U SYSFLAG_U GBV_ELV SSG-OLC-PHA GBV_ILN_20 GBV_ILN_22 GBV_ILN_23 GBV_ILN_24 GBV_ILN_31 GBV_ILN_32 GBV_ILN_40 GBV_ILN_60 GBV_ILN_62 GBV_ILN_63 GBV_ILN_65 GBV_ILN_69 GBV_ILN_70 GBV_ILN_73 GBV_ILN_74 GBV_ILN_90 GBV_ILN_95 GBV_ILN_100 GBV_ILN_101 GBV_ILN_105 GBV_ILN_110 GBV_ILN_151 GBV_ILN_224 GBV_ILN_370 GBV_ILN_602 GBV_ILN_702 GBV_ILN_2003 GBV_ILN_2004 GBV_ILN_2005 GBV_ILN_2011 GBV_ILN_2014 GBV_ILN_2015 GBV_ILN_2020 GBV_ILN_2021 GBV_ILN_2025 GBV_ILN_2027 GBV_ILN_2034 GBV_ILN_2038 GBV_ILN_2044 GBV_ILN_2048 GBV_ILN_2049 GBV_ILN_2050 GBV_ILN_2056 GBV_ILN_2059 GBV_ILN_2061 GBV_ILN_2064 GBV_ILN_2065 GBV_ILN_2068 GBV_ILN_2111 GBV_ILN_2112 GBV_ILN_2113 GBV_ILN_2118 GBV_ILN_2122 GBV_ILN_2129 GBV_ILN_2143 GBV_ILN_2147 GBV_ILN_2148 GBV_ILN_2152 GBV_ILN_2153 GBV_ILN_2190 GBV_ILN_2336 GBV_ILN_2507 GBV_ILN_2522 GBV_ILN_4035 GBV_ILN_4037 GBV_ILN_4112 GBV_ILN_4125 GBV_ILN_4126 GBV_ILN_4242 GBV_ILN_4251 GBV_ILN_4305 GBV_ILN_4313 GBV_ILN_4323 GBV_ILN_4324 GBV_ILN_4325 GBV_ILN_4326 GBV_ILN_4333 GBV_ILN_4334 GBV_ILN_4335 GBV_ILN_4338 GBV_ILN_4393 44.69 Intensivmedizin AR 51 111-116
spelling	10.1016/j.jcrc.2019.02.003 doi (DE-627)ELV002291649 (ELSEVIER)S0883-9441(18)31518-1 DE-627 ger DE-627 rda eng 610 DE-600 44.69 bkl Hinson, Jeremiah S. verfasserin aut Acute kidney injury following contrast media administration in the septic patient: A retrospective propensity-matched analysis 2019 nicht spezifiziert zzz rdacontent Computermedien c rdamedia Online-Ressource cr rdacarrier Purpose: To determine the risk for acute kidney injury (AKI) attributable to intravenous contrast media (CM) administration in septic patients.Materials and methods: This was a single-center retrospective propensity matched cohort analysis performed in the emergency department (ED) of an academic medical center. All visits for patients ≥18 years who met sepsis diagnostic criteria and had serum creatinine (SCr) measured both on arrival to the ED and again 48 to 72 h later were included. Of 4171 visits, 1464 patients underwent contrast-enhanced CT (CECT), 976 underwent unenhanced CT and 1731 underwent no CT at all.Results: The primary outcome was incidence of AKI. Logistic regression and between-groups odds ratios with and without propensity-score matching were used to test for an independent association between CM administration and AKI. Incidence of AKI was 7.2%, 9.4% and 9.7% in those who underwent CECT, unenhanced CT and no CT. CM administration was not associated with increased incidence of AKI.Conclusions: Sepsis is a medical emergency proven to benefit from early diagnosis and rapid initiation of treatment, which is often aided by CECT. Our findings argue against withholding CM for fear of precipitating AKI in potentially septic patients. Acute kidney injury Sepsis Contrast media Contrast-induced nephropathy Al Jalbout, Nour verfasserin (orcid)0000-0002-9369-0260 aut Ehmann, Michael R. verfasserin aut Klein, Eili Y. verfasserin aut Enthalten in Journal of critical care [Amsterdam] : Elsevier, 1986 51, Seite 111-116 Online-Ressource (DE-627)326646167 (DE-600)2041640-4 (DE-576)096188820 1557-8615 nnns volume:51 pages:111-116 GBV_USEFLAG_U SYSFLAG_U GBV_ELV SSG-OLC-PHA GBV_ILN_20 GBV_ILN_22 GBV_ILN_23 GBV_ILN_24 GBV_ILN_31 GBV_ILN_32 GBV_ILN_40 GBV_ILN_60 GBV_ILN_62 GBV_ILN_63 GBV_ILN_65 GBV_ILN_69 GBV_ILN_70 GBV_ILN_73 GBV_ILN_74 GBV_ILN_90 GBV_ILN_95 GBV_ILN_100 GBV_ILN_101 GBV_ILN_105 GBV_ILN_110 GBV_ILN_151 GBV_ILN_224 GBV_ILN_370 GBV_ILN_602 GBV_ILN_702 GBV_ILN_2003 GBV_ILN_2004 GBV_ILN_2005 GBV_ILN_2011 GBV_ILN_2014 GBV_ILN_2015 GBV_ILN_2020 GBV_ILN_2021 GBV_ILN_2025 GBV_ILN_2027 GBV_ILN_2034 GBV_ILN_2038 GBV_ILN_2044 GBV_ILN_2048 GBV_ILN_2049 GBV_ILN_2050 GBV_ILN_2056 GBV_ILN_2059 GBV_ILN_2061 GBV_ILN_2064 GBV_ILN_2065 GBV_ILN_2068 GBV_ILN_2111 GBV_ILN_2112 GBV_ILN_2113 GBV_ILN_2118 GBV_ILN_2122 GBV_ILN_2129 GBV_ILN_2143 GBV_ILN_2147 GBV_ILN_2148 GBV_ILN_2152 GBV_ILN_2153 GBV_ILN_2190 GBV_ILN_2336 GBV_ILN_2507 GBV_ILN_2522 GBV_ILN_4035 GBV_ILN_4037 GBV_ILN_4112 GBV_ILN_4125 GBV_ILN_4126 GBV_ILN_4242 GBV_ILN_4251 GBV_ILN_4305 GBV_ILN_4313 GBV_ILN_4323 GBV_ILN_4324 GBV_ILN_4325 GBV_ILN_4326 GBV_ILN_4333 GBV_ILN_4334 GBV_ILN_4335 GBV_ILN_4338 GBV_ILN_4393 44.69 Intensivmedizin AR 51 111-116
allfields_unstemmed	10.1016/j.jcrc.2019.02.003 doi (DE-627)ELV002291649 (ELSEVIER)S0883-9441(18)31518-1 DE-627 ger DE-627 rda eng 610 DE-600 44.69 bkl Hinson, Jeremiah S. verfasserin aut Acute kidney injury following contrast media administration in the septic patient: A retrospective propensity-matched analysis 2019 nicht spezifiziert zzz rdacontent Computermedien c rdamedia Online-Ressource cr rdacarrier Purpose: To determine the risk for acute kidney injury (AKI) attributable to intravenous contrast media (CM) administration in septic patients.Materials and methods: This was a single-center retrospective propensity matched cohort analysis performed in the emergency department (ED) of an academic medical center. All visits for patients ≥18 years who met sepsis diagnostic criteria and had serum creatinine (SCr) measured both on arrival to the ED and again 48 to 72 h later were included. Of 4171 visits, 1464 patients underwent contrast-enhanced CT (CECT), 976 underwent unenhanced CT and 1731 underwent no CT at all.Results: The primary outcome was incidence of AKI. Logistic regression and between-groups odds ratios with and without propensity-score matching were used to test for an independent association between CM administration and AKI. Incidence of AKI was 7.2%, 9.4% and 9.7% in those who underwent CECT, unenhanced CT and no CT. CM administration was not associated with increased incidence of AKI.Conclusions: Sepsis is a medical emergency proven to benefit from early diagnosis and rapid initiation of treatment, which is often aided by CECT. Our findings argue against withholding CM for fear of precipitating AKI in potentially septic patients. Acute kidney injury Sepsis Contrast media Contrast-induced nephropathy Al Jalbout, Nour verfasserin (orcid)0000-0002-9369-0260 aut Ehmann, Michael R. verfasserin aut Klein, Eili Y. verfasserin aut Enthalten in Journal of critical care [Amsterdam] : Elsevier, 1986 51, Seite 111-116 Online-Ressource (DE-627)326646167 (DE-600)2041640-4 (DE-576)096188820 1557-8615 nnns volume:51 pages:111-116 GBV_USEFLAG_U SYSFLAG_U GBV_ELV SSG-OLC-PHA GBV_ILN_20 GBV_ILN_22 GBV_ILN_23 GBV_ILN_24 GBV_ILN_31 GBV_ILN_32 GBV_ILN_40 GBV_ILN_60 GBV_ILN_62 GBV_ILN_63 GBV_ILN_65 GBV_ILN_69 GBV_ILN_70 GBV_ILN_73 GBV_ILN_74 GBV_ILN_90 GBV_ILN_95 GBV_ILN_100 GBV_ILN_101 GBV_ILN_105 GBV_ILN_110 GBV_ILN_151 GBV_ILN_224 GBV_ILN_370 GBV_ILN_602 GBV_ILN_702 GBV_ILN_2003 GBV_ILN_2004 GBV_ILN_2005 GBV_ILN_2011 GBV_ILN_2014 GBV_ILN_2015 GBV_ILN_2020 GBV_ILN_2021 GBV_ILN_2025 GBV_ILN_2027 GBV_ILN_2034 GBV_ILN_2038 GBV_ILN_2044 GBV_ILN_2048 GBV_ILN_2049 GBV_ILN_2050 GBV_ILN_2056 GBV_ILN_2059 GBV_ILN_2061 GBV_ILN_2064 GBV_ILN_2065 GBV_ILN_2068 GBV_ILN_2111 GBV_ILN_2112 GBV_ILN_2113 GBV_ILN_2118 GBV_ILN_2122 GBV_ILN_2129 GBV_ILN_2143 GBV_ILN_2147 GBV_ILN_2148 GBV_ILN_2152 GBV_ILN_2153 GBV_ILN_2190 GBV_ILN_2336 GBV_ILN_2507 GBV_ILN_2522 GBV_ILN_4035 GBV_ILN_4037 GBV_ILN_4112 GBV_ILN_4125 GBV_ILN_4126 GBV_ILN_4242 GBV_ILN_4251 GBV_ILN_4305 GBV_ILN_4313 GBV_ILN_4323 GBV_ILN_4324 GBV_ILN_4325 GBV_ILN_4326 GBV_ILN_4333 GBV_ILN_4334 GBV_ILN_4335 GBV_ILN_4338 GBV_ILN_4393 44.69 Intensivmedizin AR 51 111-116
allfieldsGer	10.1016/j.jcrc.2019.02.003 doi (DE-627)ELV002291649 (ELSEVIER)S0883-9441(18)31518-1 DE-627 ger DE-627 rda eng 610 DE-600 44.69 bkl Hinson, Jeremiah S. verfasserin aut Acute kidney injury following contrast media administration in the septic patient: A retrospective propensity-matched analysis 2019 nicht spezifiziert zzz rdacontent Computermedien c rdamedia Online-Ressource cr rdacarrier Purpose: To determine the risk for acute kidney injury (AKI) attributable to intravenous contrast media (CM) administration in septic patients.Materials and methods: This was a single-center retrospective propensity matched cohort analysis performed in the emergency department (ED) of an academic medical center. All visits for patients ≥18 years who met sepsis diagnostic criteria and had serum creatinine (SCr) measured both on arrival to the ED and again 48 to 72 h later were included. Of 4171 visits, 1464 patients underwent contrast-enhanced CT (CECT), 976 underwent unenhanced CT and 1731 underwent no CT at all.Results: The primary outcome was incidence of AKI. Logistic regression and between-groups odds ratios with and without propensity-score matching were used to test for an independent association between CM administration and AKI. Incidence of AKI was 7.2%, 9.4% and 9.7% in those who underwent CECT, unenhanced CT and no CT. CM administration was not associated with increased incidence of AKI.Conclusions: Sepsis is a medical emergency proven to benefit from early diagnosis and rapid initiation of treatment, which is often aided by CECT. Our findings argue against withholding CM for fear of precipitating AKI in potentially septic patients. Acute kidney injury Sepsis Contrast media Contrast-induced nephropathy Al Jalbout, Nour verfasserin (orcid)0000-0002-9369-0260 aut Ehmann, Michael R. verfasserin aut Klein, Eili Y. verfasserin aut Enthalten in Journal of critical care [Amsterdam] : Elsevier, 1986 51, Seite 111-116 Online-Ressource (DE-627)326646167 (DE-600)2041640-4 (DE-576)096188820 1557-8615 nnns volume:51 pages:111-116 GBV_USEFLAG_U SYSFLAG_U GBV_ELV SSG-OLC-PHA GBV_ILN_20 GBV_ILN_22 GBV_ILN_23 GBV_ILN_24 GBV_ILN_31 GBV_ILN_32 GBV_ILN_40 GBV_ILN_60 GBV_ILN_62 GBV_ILN_63 GBV_ILN_65 GBV_ILN_69 GBV_ILN_70 GBV_ILN_73 GBV_ILN_74 GBV_ILN_90 GBV_ILN_95 GBV_ILN_100 GBV_ILN_101 GBV_ILN_105 GBV_ILN_110 GBV_ILN_151 GBV_ILN_224 GBV_ILN_370 GBV_ILN_602 GBV_ILN_702 GBV_ILN_2003 GBV_ILN_2004 GBV_ILN_2005 GBV_ILN_2011 GBV_ILN_2014 GBV_ILN_2015 GBV_ILN_2020 GBV_ILN_2021 GBV_ILN_2025 GBV_ILN_2027 GBV_ILN_2034 GBV_ILN_2038 GBV_ILN_2044 GBV_ILN_2048 GBV_ILN_2049 GBV_ILN_2050 GBV_ILN_2056 GBV_ILN_2059 GBV_ILN_2061 GBV_ILN_2064 GBV_ILN_2065 GBV_ILN_2068 GBV_ILN_2111 GBV_ILN_2112 GBV_ILN_2113 GBV_ILN_2118 GBV_ILN_2122 GBV_ILN_2129 GBV_ILN_2143 GBV_ILN_2147 GBV_ILN_2148 GBV_ILN_2152 GBV_ILN_2153 GBV_ILN_2190 GBV_ILN_2336 GBV_ILN_2507 GBV_ILN_2522 GBV_ILN_4035 GBV_ILN_4037 GBV_ILN_4112 GBV_ILN_4125 GBV_ILN_4126 GBV_ILN_4242 GBV_ILN_4251 GBV_ILN_4305 GBV_ILN_4313 GBV_ILN_4323 GBV_ILN_4324 GBV_ILN_4325 GBV_ILN_4326 GBV_ILN_4333 GBV_ILN_4334 GBV_ILN_4335 GBV_ILN_4338 GBV_ILN_4393 44.69 Intensivmedizin AR 51 111-116
allfieldsSound	10.1016/j.jcrc.2019.02.003 doi (DE-627)ELV002291649 (ELSEVIER)S0883-9441(18)31518-1 DE-627 ger DE-627 rda eng 610 DE-600 44.69 bkl Hinson, Jeremiah S. verfasserin aut Acute kidney injury following contrast media administration in the septic patient: A retrospective propensity-matched analysis 2019 nicht spezifiziert zzz rdacontent Computermedien c rdamedia Online-Ressource cr rdacarrier Purpose: To determine the risk for acute kidney injury (AKI) attributable to intravenous contrast media (CM) administration in septic patients.Materials and methods: This was a single-center retrospective propensity matched cohort analysis performed in the emergency department (ED) of an academic medical center. All visits for patients ≥18 years who met sepsis diagnostic criteria and had serum creatinine (SCr) measured both on arrival to the ED and again 48 to 72 h later were included. Of 4171 visits, 1464 patients underwent contrast-enhanced CT (CECT), 976 underwent unenhanced CT and 1731 underwent no CT at all.Results: The primary outcome was incidence of AKI. Logistic regression and between-groups odds ratios with and without propensity-score matching were used to test for an independent association between CM administration and AKI. Incidence of AKI was 7.2%, 9.4% and 9.7% in those who underwent CECT, unenhanced CT and no CT. CM administration was not associated with increased incidence of AKI.Conclusions: Sepsis is a medical emergency proven to benefit from early diagnosis and rapid initiation of treatment, which is often aided by CECT. Our findings argue against withholding CM for fear of precipitating AKI in potentially septic patients. Acute kidney injury Sepsis Contrast media Contrast-induced nephropathy Al Jalbout, Nour verfasserin (orcid)0000-0002-9369-0260 aut Ehmann, Michael R. verfasserin aut Klein, Eili Y. verfasserin aut Enthalten in Journal of critical care [Amsterdam] : Elsevier, 1986 51, Seite 111-116 Online-Ressource (DE-627)326646167 (DE-600)2041640-4 (DE-576)096188820 1557-8615 nnns volume:51 pages:111-116 GBV_USEFLAG_U SYSFLAG_U GBV_ELV SSG-OLC-PHA GBV_ILN_20 GBV_ILN_22 GBV_ILN_23 GBV_ILN_24 GBV_ILN_31 GBV_ILN_32 GBV_ILN_40 GBV_ILN_60 GBV_ILN_62 GBV_ILN_63 GBV_ILN_65 GBV_ILN_69 GBV_ILN_70 GBV_ILN_73 GBV_ILN_74 GBV_ILN_90 GBV_ILN_95 GBV_ILN_100 GBV_ILN_101 GBV_ILN_105 GBV_ILN_110 GBV_ILN_151 GBV_ILN_224 GBV_ILN_370 GBV_ILN_602 GBV_ILN_702 GBV_ILN_2003 GBV_ILN_2004 GBV_ILN_2005 GBV_ILN_2011 GBV_ILN_2014 GBV_ILN_2015 GBV_ILN_2020 GBV_ILN_2021 GBV_ILN_2025 GBV_ILN_2027 GBV_ILN_2034 GBV_ILN_2038 GBV_ILN_2044 GBV_ILN_2048 GBV_ILN_2049 GBV_ILN_2050 GBV_ILN_2056 GBV_ILN_2059 GBV_ILN_2061 GBV_ILN_2064 GBV_ILN_2065 GBV_ILN_2068 GBV_ILN_2111 GBV_ILN_2112 GBV_ILN_2113 GBV_ILN_2118 GBV_ILN_2122 GBV_ILN_2129 GBV_ILN_2143 GBV_ILN_2147 GBV_ILN_2148 GBV_ILN_2152 GBV_ILN_2153 GBV_ILN_2190 GBV_ILN_2336 GBV_ILN_2507 GBV_ILN_2522 GBV_ILN_4035 GBV_ILN_4037 GBV_ILN_4112 GBV_ILN_4125 GBV_ILN_4126 GBV_ILN_4242 GBV_ILN_4251 GBV_ILN_4305 GBV_ILN_4313 GBV_ILN_4323 GBV_ILN_4324 GBV_ILN_4325 GBV_ILN_4326 GBV_ILN_4333 GBV_ILN_4334 GBV_ILN_4335 GBV_ILN_4338 GBV_ILN_4393 44.69 Intensivmedizin AR 51 111-116
language	English
source	Enthalten in Journal of critical care 51, Seite 111-116 volume:51 pages:111-116
sourceStr	Enthalten in Journal of critical care 51, Seite 111-116 volume:51 pages:111-116
format_phy_str_mv	Article
bklname	Intensivmedizin
institution	findex.gbv.de
topic_facet	Acute kidney injury Sepsis Contrast media Contrast-induced nephropathy
dewey-raw	610
isfreeaccess_bool	false
container_title	Journal of critical care
authorswithroles_txt_mv	Hinson, Jeremiah S. @@aut@@ Al Jalbout, Nour @@aut@@ Ehmann, Michael R. @@aut@@ Klein, Eili Y. @@aut@@
publishDateDaySort_date	2019-01-01T00:00:00Z
hierarchy_top_id	326646167
dewey-sort	3610
id	ELV002291649
language_de	englisch
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author	Hinson, Jeremiah S.
spellingShingle	Hinson, Jeremiah S. ddc 610 bkl 44.69 misc Acute kidney injury misc Sepsis misc Contrast media misc Contrast-induced nephropathy Acute kidney injury following contrast media administration in the septic patient: A retrospective propensity-matched analysis
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topic_title	610 DE-600 44.69 bkl Acute kidney injury following contrast media administration in the septic patient: A retrospective propensity-matched analysis Acute kidney injury Sepsis Contrast media Contrast-induced nephropathy
topic	ddc 610 bkl 44.69 misc Acute kidney injury misc Sepsis misc Contrast media misc Contrast-induced nephropathy
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title	Acute kidney injury following contrast media administration in the septic patient: A retrospective propensity-matched analysis
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title_full	Acute kidney injury following contrast media administration in the septic patient: A retrospective propensity-matched analysis
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title_sort	acute kidney injury following contrast media administration in the septic patient: a retrospective propensity-matched analysis
title_auth	Acute kidney injury following contrast media administration in the septic patient: A retrospective propensity-matched analysis
abstract	Purpose: To determine the risk for acute kidney injury (AKI) attributable to intravenous contrast media (CM) administration in septic patients.Materials and methods: This was a single-center retrospective propensity matched cohort analysis performed in the emergency department (ED) of an academic medical center. All visits for patients ≥18 years who met sepsis diagnostic criteria and had serum creatinine (SCr) measured both on arrival to the ED and again 48 to 72 h later were included. Of 4171 visits, 1464 patients underwent contrast-enhanced CT (CECT), 976 underwent unenhanced CT and 1731 underwent no CT at all.Results: The primary outcome was incidence of AKI. Logistic regression and between-groups odds ratios with and without propensity-score matching were used to test for an independent association between CM administration and AKI. Incidence of AKI was 7.2%, 9.4% and 9.7% in those who underwent CECT, unenhanced CT and no CT. CM administration was not associated with increased incidence of AKI.Conclusions: Sepsis is a medical emergency proven to benefit from early diagnosis and rapid initiation of treatment, which is often aided by CECT. Our findings argue against withholding CM for fear of precipitating AKI in potentially septic patients.
abstractGer	Purpose: To determine the risk for acute kidney injury (AKI) attributable to intravenous contrast media (CM) administration in septic patients.Materials and methods: This was a single-center retrospective propensity matched cohort analysis performed in the emergency department (ED) of an academic medical center. All visits for patients ≥18 years who met sepsis diagnostic criteria and had serum creatinine (SCr) measured both on arrival to the ED and again 48 to 72 h later were included. Of 4171 visits, 1464 patients underwent contrast-enhanced CT (CECT), 976 underwent unenhanced CT and 1731 underwent no CT at all.Results: The primary outcome was incidence of AKI. Logistic regression and between-groups odds ratios with and without propensity-score matching were used to test for an independent association between CM administration and AKI. Incidence of AKI was 7.2%, 9.4% and 9.7% in those who underwent CECT, unenhanced CT and no CT. CM administration was not associated with increased incidence of AKI.Conclusions: Sepsis is a medical emergency proven to benefit from early diagnosis and rapid initiation of treatment, which is often aided by CECT. Our findings argue against withholding CM for fear of precipitating AKI in potentially septic patients.
abstract_unstemmed	Purpose: To determine the risk for acute kidney injury (AKI) attributable to intravenous contrast media (CM) administration in septic patients.Materials and methods: This was a single-center retrospective propensity matched cohort analysis performed in the emergency department (ED) of an academic medical center. All visits for patients ≥18 years who met sepsis diagnostic criteria and had serum creatinine (SCr) measured both on arrival to the ED and again 48 to 72 h later were included. Of 4171 visits, 1464 patients underwent contrast-enhanced CT (CECT), 976 underwent unenhanced CT and 1731 underwent no CT at all.Results: The primary outcome was incidence of AKI. Logistic regression and between-groups odds ratios with and without propensity-score matching were used to test for an independent association between CM administration and AKI. Incidence of AKI was 7.2%, 9.4% and 9.7% in those who underwent CECT, unenhanced CT and no CT. CM administration was not associated with increased incidence of AKI.Conclusions: Sepsis is a medical emergency proven to benefit from early diagnosis and rapid initiation of treatment, which is often aided by CECT. Our findings argue against withholding CM for fear of precipitating AKI in potentially septic patients.
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title_short	Acute kidney injury following contrast media administration in the septic patient: A retrospective propensity-matched analysis
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up_date	2024-07-07T00:14:37.882Z
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Acute kidney injury following contrast media administration in the septic patient: A retrospective propensity-matched analysis

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