N-(3-Ethoxy-phenyl)-4-pyrrolidin-1-yl-3-trifluoromethyl-benzamide (EPPTB) prevents 3-iodothyronamine (T1AM)-induced neuroprotection against kainic acid toxicity

Thyroid hormone and thyroid hormone metabolites, including 3-iodothyronamine (T1AM) and 3-iodothyroacetic acid (TA1), activate AKT signaling in hippocampal neurons affording protection from excitotoxic damage. We aim to explore whether the mechanism of T1AM neuroprotection against kainic acid (KA)-i...
Ausführliche Beschreibung

Gespeichert in:
Autor*in:

Landucci, Elisa [verfasserIn]

Gencarelli, Manuela [verfasserIn]

Mazzantini, Costanza [verfasserIn]

Laurino, Annunziatina [verfasserIn]

Pellegrini-Giampietro, Domenico Edoardo [verfasserIn]

Raimondi, Laura [verfasserIn]

Format:

E-Artikel

Sprache:

Englisch

Erschienen:

2019

Schlagwörter:

3-iodothyroanmine

T1AM

3-iodothyroacetic acid

TA1

Trace amine associated receptor isoform 1

TAAR1

Protein kinase B

AKT

Protein kinase A

PKA

Organotypic hippocampal slices

Übergeordnetes Werk:

Enthalten in: Neurochemistry international - Amsterdam [u.a.] : Elsevier Science, 1980, 129

Übergeordnetes Werk:

volume:129

DOI / URN:

10.1016/j.neuint.2019.05.004

Katalog-ID:

ELV002719746

Nicht das Richtige dabei?

Schreiben Sie uns!