Lifestyle and dietary environmental factors in colorectal cancer susceptibility
Colorectal cancer (CRC) incidence changes with time and by variations in diet and lifestyle, as evidenced historically by migrant studies and recently by extensive epidemiologic evidence. The worldwide heterogeneity in CRC incidence is strongly suggestive of etiological involvement of environmental...
Ausführliche Beschreibung
Gespeichert in:
| Autor*in: |
Murphy, Neil [verfasserIn] Moreno, Victor [verfasserIn] Hughes, David J. [verfasserIn] Vodicka, Ludmila [verfasserIn] Vodicka, Pavel [verfasserIn] Aglago, Elom K. [verfasserIn] Gunter, Marc J. [verfasserIn] Jenab, Mazda [verfasserIn] |
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| Format: |
E-Artikel |
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| Sprache: |
Englisch |
| Erschienen: |
2019 |
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| Schlagwörter: |
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| Übergeordnetes Werk: |
Enthalten in: Molecular aspects of medicine - Amsterdam [u.a.] : Elsevier Science, 1976, 69, Seite 2-9 |
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| Übergeordnetes Werk: |
volume:69 ; pages:2-9 |
| DOI / URN: |
10.1016/j.mam.2019.06.005 |
|---|
| Katalog-ID: |
ELV00288478X |
|---|
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| 245 | 1 | 0 | |a Lifestyle and dietary environmental factors in colorectal cancer susceptibility |
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| 520 | |a Colorectal cancer (CRC) incidence changes with time and by variations in diet and lifestyle, as evidenced historically by migrant studies and recently by extensive epidemiologic evidence. The worldwide heterogeneity in CRC incidence is strongly suggestive of etiological involvement of environmental exposures, particularly lifestyle and diet. It is established that physical inactivity, obesity and some dietary factors (red/processed meats, alcohol) are positively associated with CRC, while healthy lifestyle habits show inverse associations. Mechanistic evidence shows that lifestyle and dietary components that contribute to energy excess are linked with increased CRC via metabolic dysfunction, inflammation, oxidative stress, bacterial dysbiosis and breakdown of gut barrier integrity while the reverse is apparent for components associated with decreased risk. This chapter will review the available evidence on lifestyle and dietary factors in CRC etiology and their underlying mechanisms in CRC development. This short review will also touch upon available information on potential gene-environment interactions, molecular sub-types of CRC and anatomical sub-sites within the colorectum. | ||
| 650 | 4 | |a Colorectal cancer | |
| 650 | 4 | |a Environment | |
| 650 | 4 | |a Diet | |
| 650 | 4 | |a Lifestyle | |
| 650 | 4 | |a Obesity | |
| 650 | 4 | |a Etiology | |
| 650 | 4 | |a Mechanisms | |
| 650 | 4 | |a Genetic interactions | |
| 700 | 1 | |a Moreno, Victor |e verfasserin |4 aut | |
| 700 | 1 | |a Hughes, David J. |e verfasserin |4 aut | |
| 700 | 1 | |a Vodicka, Ludmila |e verfasserin |4 aut | |
| 700 | 1 | |a Vodicka, Pavel |e verfasserin |4 aut | |
| 700 | 1 | |a Aglago, Elom K. |e verfasserin |4 aut | |
| 700 | 1 | |a Gunter, Marc J. |e verfasserin |4 aut | |
| 700 | 1 | |a Jenab, Mazda |e verfasserin |4 aut | |
| 773 | 0 | 8 | |i Enthalten in |t Molecular aspects of medicine |d Amsterdam [u.a.] : Elsevier Science, 1976 |g 69, Seite 2-9 |h Online-Ressource |w (DE-627)32046847X |w (DE-600)2008203-4 |w (DE-576)096290552 |x 1872-9452 |7 nnns |
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10.1016/j.mam.2019.06.005 doi (DE-627)ELV00288478X (ELSEVIER)S0098-2997(19)30033-0 DE-627 ger DE-627 rda eng 610 DE-600 44.09 bkl Murphy, Neil verfasserin aut Lifestyle and dietary environmental factors in colorectal cancer susceptibility 2019 nicht spezifiziert zzz rdacontent Computermedien c rdamedia Online-Ressource cr rdacarrier Colorectal cancer (CRC) incidence changes with time and by variations in diet and lifestyle, as evidenced historically by migrant studies and recently by extensive epidemiologic evidence. The worldwide heterogeneity in CRC incidence is strongly suggestive of etiological involvement of environmental exposures, particularly lifestyle and diet. It is established that physical inactivity, obesity and some dietary factors (red/processed meats, alcohol) are positively associated with CRC, while healthy lifestyle habits show inverse associations. Mechanistic evidence shows that lifestyle and dietary components that contribute to energy excess are linked with increased CRC via metabolic dysfunction, inflammation, oxidative stress, bacterial dysbiosis and breakdown of gut barrier integrity while the reverse is apparent for components associated with decreased risk. This chapter will review the available evidence on lifestyle and dietary factors in CRC etiology and their underlying mechanisms in CRC development. This short review will also touch upon available information on potential gene-environment interactions, molecular sub-types of CRC and anatomical sub-sites within the colorectum. Colorectal cancer Environment Diet Lifestyle Obesity Etiology Mechanisms Genetic interactions Moreno, Victor verfasserin aut Hughes, David J. verfasserin aut Vodicka, Ludmila verfasserin aut Vodicka, Pavel verfasserin aut Aglago, Elom K. verfasserin aut Gunter, Marc J. verfasserin aut Jenab, Mazda verfasserin aut Enthalten in Molecular aspects of medicine Amsterdam [u.a.] : Elsevier Science, 1976 69, Seite 2-9 Online-Ressource (DE-627)32046847X (DE-600)2008203-4 (DE-576)096290552 1872-9452 nnns volume:69 pages:2-9 GBV_USEFLAG_U SYSFLAG_U GBV_ELV SSG-OLC-PHA GBV_ILN_20 GBV_ILN_22 GBV_ILN_23 GBV_ILN_24 GBV_ILN_31 GBV_ILN_32 GBV_ILN_40 GBV_ILN_60 GBV_ILN_62 GBV_ILN_63 GBV_ILN_69 GBV_ILN_70 GBV_ILN_73 GBV_ILN_74 GBV_ILN_90 GBV_ILN_95 GBV_ILN_100 GBV_ILN_101 GBV_ILN_105 GBV_ILN_110 GBV_ILN_151 GBV_ILN_224 GBV_ILN_370 GBV_ILN_602 GBV_ILN_702 GBV_ILN_2003 GBV_ILN_2004 GBV_ILN_2005 GBV_ILN_2011 GBV_ILN_2014 GBV_ILN_2015 GBV_ILN_2020 GBV_ILN_2021 GBV_ILN_2025 GBV_ILN_2027 GBV_ILN_2034 GBV_ILN_2038 GBV_ILN_2044 GBV_ILN_2048 GBV_ILN_2049 GBV_ILN_2050 GBV_ILN_2056 GBV_ILN_2059 GBV_ILN_2061 GBV_ILN_2064 GBV_ILN_2065 GBV_ILN_2068 GBV_ILN_2111 GBV_ILN_2112 GBV_ILN_2113 GBV_ILN_2118 GBV_ILN_2122 GBV_ILN_2129 GBV_ILN_2143 GBV_ILN_2147 GBV_ILN_2148 GBV_ILN_2152 GBV_ILN_2153 GBV_ILN_2190 GBV_ILN_2336 GBV_ILN_2507 GBV_ILN_2522 GBV_ILN_4035 GBV_ILN_4037 GBV_ILN_4112 GBV_ILN_4125 GBV_ILN_4126 GBV_ILN_4242 GBV_ILN_4251 GBV_ILN_4305 GBV_ILN_4313 GBV_ILN_4323 GBV_ILN_4324 GBV_ILN_4326 GBV_ILN_4333 GBV_ILN_4334 GBV_ILN_4335 GBV_ILN_4338 GBV_ILN_4393 44.09 Medizintechnik AR 69 2-9 |
| spelling |
10.1016/j.mam.2019.06.005 doi (DE-627)ELV00288478X (ELSEVIER)S0098-2997(19)30033-0 DE-627 ger DE-627 rda eng 610 DE-600 44.09 bkl Murphy, Neil verfasserin aut Lifestyle and dietary environmental factors in colorectal cancer susceptibility 2019 nicht spezifiziert zzz rdacontent Computermedien c rdamedia Online-Ressource cr rdacarrier Colorectal cancer (CRC) incidence changes with time and by variations in diet and lifestyle, as evidenced historically by migrant studies and recently by extensive epidemiologic evidence. The worldwide heterogeneity in CRC incidence is strongly suggestive of etiological involvement of environmental exposures, particularly lifestyle and diet. It is established that physical inactivity, obesity and some dietary factors (red/processed meats, alcohol) are positively associated with CRC, while healthy lifestyle habits show inverse associations. Mechanistic evidence shows that lifestyle and dietary components that contribute to energy excess are linked with increased CRC via metabolic dysfunction, inflammation, oxidative stress, bacterial dysbiosis and breakdown of gut barrier integrity while the reverse is apparent for components associated with decreased risk. This chapter will review the available evidence on lifestyle and dietary factors in CRC etiology and their underlying mechanisms in CRC development. This short review will also touch upon available information on potential gene-environment interactions, molecular sub-types of CRC and anatomical sub-sites within the colorectum. Colorectal cancer Environment Diet Lifestyle Obesity Etiology Mechanisms Genetic interactions Moreno, Victor verfasserin aut Hughes, David J. verfasserin aut Vodicka, Ludmila verfasserin aut Vodicka, Pavel verfasserin aut Aglago, Elom K. verfasserin aut Gunter, Marc J. verfasserin aut Jenab, Mazda verfasserin aut Enthalten in Molecular aspects of medicine Amsterdam [u.a.] : Elsevier Science, 1976 69, Seite 2-9 Online-Ressource (DE-627)32046847X (DE-600)2008203-4 (DE-576)096290552 1872-9452 nnns volume:69 pages:2-9 GBV_USEFLAG_U SYSFLAG_U GBV_ELV SSG-OLC-PHA GBV_ILN_20 GBV_ILN_22 GBV_ILN_23 GBV_ILN_24 GBV_ILN_31 GBV_ILN_32 GBV_ILN_40 GBV_ILN_60 GBV_ILN_62 GBV_ILN_63 GBV_ILN_69 GBV_ILN_70 GBV_ILN_73 GBV_ILN_74 GBV_ILN_90 GBV_ILN_95 GBV_ILN_100 GBV_ILN_101 GBV_ILN_105 GBV_ILN_110 GBV_ILN_151 GBV_ILN_224 GBV_ILN_370 GBV_ILN_602 GBV_ILN_702 GBV_ILN_2003 GBV_ILN_2004 GBV_ILN_2005 GBV_ILN_2011 GBV_ILN_2014 GBV_ILN_2015 GBV_ILN_2020 GBV_ILN_2021 GBV_ILN_2025 GBV_ILN_2027 GBV_ILN_2034 GBV_ILN_2038 GBV_ILN_2044 GBV_ILN_2048 GBV_ILN_2049 GBV_ILN_2050 GBV_ILN_2056 GBV_ILN_2059 GBV_ILN_2061 GBV_ILN_2064 GBV_ILN_2065 GBV_ILN_2068 GBV_ILN_2111 GBV_ILN_2112 GBV_ILN_2113 GBV_ILN_2118 GBV_ILN_2122 GBV_ILN_2129 GBV_ILN_2143 GBV_ILN_2147 GBV_ILN_2148 GBV_ILN_2152 GBV_ILN_2153 GBV_ILN_2190 GBV_ILN_2336 GBV_ILN_2507 GBV_ILN_2522 GBV_ILN_4035 GBV_ILN_4037 GBV_ILN_4112 GBV_ILN_4125 GBV_ILN_4126 GBV_ILN_4242 GBV_ILN_4251 GBV_ILN_4305 GBV_ILN_4313 GBV_ILN_4323 GBV_ILN_4324 GBV_ILN_4326 GBV_ILN_4333 GBV_ILN_4334 GBV_ILN_4335 GBV_ILN_4338 GBV_ILN_4393 44.09 Medizintechnik AR 69 2-9 |
| allfields_unstemmed |
10.1016/j.mam.2019.06.005 doi (DE-627)ELV00288478X (ELSEVIER)S0098-2997(19)30033-0 DE-627 ger DE-627 rda eng 610 DE-600 44.09 bkl Murphy, Neil verfasserin aut Lifestyle and dietary environmental factors in colorectal cancer susceptibility 2019 nicht spezifiziert zzz rdacontent Computermedien c rdamedia Online-Ressource cr rdacarrier Colorectal cancer (CRC) incidence changes with time and by variations in diet and lifestyle, as evidenced historically by migrant studies and recently by extensive epidemiologic evidence. The worldwide heterogeneity in CRC incidence is strongly suggestive of etiological involvement of environmental exposures, particularly lifestyle and diet. It is established that physical inactivity, obesity and some dietary factors (red/processed meats, alcohol) are positively associated with CRC, while healthy lifestyle habits show inverse associations. Mechanistic evidence shows that lifestyle and dietary components that contribute to energy excess are linked with increased CRC via metabolic dysfunction, inflammation, oxidative stress, bacterial dysbiosis and breakdown of gut barrier integrity while the reverse is apparent for components associated with decreased risk. This chapter will review the available evidence on lifestyle and dietary factors in CRC etiology and their underlying mechanisms in CRC development. This short review will also touch upon available information on potential gene-environment interactions, molecular sub-types of CRC and anatomical sub-sites within the colorectum. Colorectal cancer Environment Diet Lifestyle Obesity Etiology Mechanisms Genetic interactions Moreno, Victor verfasserin aut Hughes, David J. verfasserin aut Vodicka, Ludmila verfasserin aut Vodicka, Pavel verfasserin aut Aglago, Elom K. verfasserin aut Gunter, Marc J. verfasserin aut Jenab, Mazda verfasserin aut Enthalten in Molecular aspects of medicine Amsterdam [u.a.] : Elsevier Science, 1976 69, Seite 2-9 Online-Ressource (DE-627)32046847X (DE-600)2008203-4 (DE-576)096290552 1872-9452 nnns volume:69 pages:2-9 GBV_USEFLAG_U SYSFLAG_U GBV_ELV SSG-OLC-PHA GBV_ILN_20 GBV_ILN_22 GBV_ILN_23 GBV_ILN_24 GBV_ILN_31 GBV_ILN_32 GBV_ILN_40 GBV_ILN_60 GBV_ILN_62 GBV_ILN_63 GBV_ILN_69 GBV_ILN_70 GBV_ILN_73 GBV_ILN_74 GBV_ILN_90 GBV_ILN_95 GBV_ILN_100 GBV_ILN_101 GBV_ILN_105 GBV_ILN_110 GBV_ILN_151 GBV_ILN_224 GBV_ILN_370 GBV_ILN_602 GBV_ILN_702 GBV_ILN_2003 GBV_ILN_2004 GBV_ILN_2005 GBV_ILN_2011 GBV_ILN_2014 GBV_ILN_2015 GBV_ILN_2020 GBV_ILN_2021 GBV_ILN_2025 GBV_ILN_2027 GBV_ILN_2034 GBV_ILN_2038 GBV_ILN_2044 GBV_ILN_2048 GBV_ILN_2049 GBV_ILN_2050 GBV_ILN_2056 GBV_ILN_2059 GBV_ILN_2061 GBV_ILN_2064 GBV_ILN_2065 GBV_ILN_2068 GBV_ILN_2111 GBV_ILN_2112 GBV_ILN_2113 GBV_ILN_2118 GBV_ILN_2122 GBV_ILN_2129 GBV_ILN_2143 GBV_ILN_2147 GBV_ILN_2148 GBV_ILN_2152 GBV_ILN_2153 GBV_ILN_2190 GBV_ILN_2336 GBV_ILN_2507 GBV_ILN_2522 GBV_ILN_4035 GBV_ILN_4037 GBV_ILN_4112 GBV_ILN_4125 GBV_ILN_4126 GBV_ILN_4242 GBV_ILN_4251 GBV_ILN_4305 GBV_ILN_4313 GBV_ILN_4323 GBV_ILN_4324 GBV_ILN_4326 GBV_ILN_4333 GBV_ILN_4334 GBV_ILN_4335 GBV_ILN_4338 GBV_ILN_4393 44.09 Medizintechnik AR 69 2-9 |
| allfieldsGer |
10.1016/j.mam.2019.06.005 doi (DE-627)ELV00288478X (ELSEVIER)S0098-2997(19)30033-0 DE-627 ger DE-627 rda eng 610 DE-600 44.09 bkl Murphy, Neil verfasserin aut Lifestyle and dietary environmental factors in colorectal cancer susceptibility 2019 nicht spezifiziert zzz rdacontent Computermedien c rdamedia Online-Ressource cr rdacarrier Colorectal cancer (CRC) incidence changes with time and by variations in diet and lifestyle, as evidenced historically by migrant studies and recently by extensive epidemiologic evidence. The worldwide heterogeneity in CRC incidence is strongly suggestive of etiological involvement of environmental exposures, particularly lifestyle and diet. It is established that physical inactivity, obesity and some dietary factors (red/processed meats, alcohol) are positively associated with CRC, while healthy lifestyle habits show inverse associations. Mechanistic evidence shows that lifestyle and dietary components that contribute to energy excess are linked with increased CRC via metabolic dysfunction, inflammation, oxidative stress, bacterial dysbiosis and breakdown of gut barrier integrity while the reverse is apparent for components associated with decreased risk. This chapter will review the available evidence on lifestyle and dietary factors in CRC etiology and their underlying mechanisms in CRC development. This short review will also touch upon available information on potential gene-environment interactions, molecular sub-types of CRC and anatomical sub-sites within the colorectum. Colorectal cancer Environment Diet Lifestyle Obesity Etiology Mechanisms Genetic interactions Moreno, Victor verfasserin aut Hughes, David J. verfasserin aut Vodicka, Ludmila verfasserin aut Vodicka, Pavel verfasserin aut Aglago, Elom K. verfasserin aut Gunter, Marc J. verfasserin aut Jenab, Mazda verfasserin aut Enthalten in Molecular aspects of medicine Amsterdam [u.a.] : Elsevier Science, 1976 69, Seite 2-9 Online-Ressource (DE-627)32046847X (DE-600)2008203-4 (DE-576)096290552 1872-9452 nnns volume:69 pages:2-9 GBV_USEFLAG_U SYSFLAG_U GBV_ELV SSG-OLC-PHA GBV_ILN_20 GBV_ILN_22 GBV_ILN_23 GBV_ILN_24 GBV_ILN_31 GBV_ILN_32 GBV_ILN_40 GBV_ILN_60 GBV_ILN_62 GBV_ILN_63 GBV_ILN_69 GBV_ILN_70 GBV_ILN_73 GBV_ILN_74 GBV_ILN_90 GBV_ILN_95 GBV_ILN_100 GBV_ILN_101 GBV_ILN_105 GBV_ILN_110 GBV_ILN_151 GBV_ILN_224 GBV_ILN_370 GBV_ILN_602 GBV_ILN_702 GBV_ILN_2003 GBV_ILN_2004 GBV_ILN_2005 GBV_ILN_2011 GBV_ILN_2014 GBV_ILN_2015 GBV_ILN_2020 GBV_ILN_2021 GBV_ILN_2025 GBV_ILN_2027 GBV_ILN_2034 GBV_ILN_2038 GBV_ILN_2044 GBV_ILN_2048 GBV_ILN_2049 GBV_ILN_2050 GBV_ILN_2056 GBV_ILN_2059 GBV_ILN_2061 GBV_ILN_2064 GBV_ILN_2065 GBV_ILN_2068 GBV_ILN_2111 GBV_ILN_2112 GBV_ILN_2113 GBV_ILN_2118 GBV_ILN_2122 GBV_ILN_2129 GBV_ILN_2143 GBV_ILN_2147 GBV_ILN_2148 GBV_ILN_2152 GBV_ILN_2153 GBV_ILN_2190 GBV_ILN_2336 GBV_ILN_2507 GBV_ILN_2522 GBV_ILN_4035 GBV_ILN_4037 GBV_ILN_4112 GBV_ILN_4125 GBV_ILN_4126 GBV_ILN_4242 GBV_ILN_4251 GBV_ILN_4305 GBV_ILN_4313 GBV_ILN_4323 GBV_ILN_4324 GBV_ILN_4326 GBV_ILN_4333 GBV_ILN_4334 GBV_ILN_4335 GBV_ILN_4338 GBV_ILN_4393 44.09 Medizintechnik AR 69 2-9 |
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Lifestyle and dietary environmental factors in colorectal cancer susceptibility |
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Murphy, Neil |
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Molecular aspects of medicine |
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Molecular aspects of medicine |
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Murphy, Neil Moreno, Victor Hughes, David J. Vodicka, Ludmila Vodicka, Pavel Aglago, Elom K. Gunter, Marc J. Jenab, Mazda |
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Elektronische Aufsätze |
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Murphy, Neil |
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10.1016/j.mam.2019.06.005 |
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610 |
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lifestyle and dietary environmental factors in colorectal cancer susceptibility |
| title_auth |
Lifestyle and dietary environmental factors in colorectal cancer susceptibility |
| abstract |
Colorectal cancer (CRC) incidence changes with time and by variations in diet and lifestyle, as evidenced historically by migrant studies and recently by extensive epidemiologic evidence. The worldwide heterogeneity in CRC incidence is strongly suggestive of etiological involvement of environmental exposures, particularly lifestyle and diet. It is established that physical inactivity, obesity and some dietary factors (red/processed meats, alcohol) are positively associated with CRC, while healthy lifestyle habits show inverse associations. Mechanistic evidence shows that lifestyle and dietary components that contribute to energy excess are linked with increased CRC via metabolic dysfunction, inflammation, oxidative stress, bacterial dysbiosis and breakdown of gut barrier integrity while the reverse is apparent for components associated with decreased risk. This chapter will review the available evidence on lifestyle and dietary factors in CRC etiology and their underlying mechanisms in CRC development. This short review will also touch upon available information on potential gene-environment interactions, molecular sub-types of CRC and anatomical sub-sites within the colorectum. |
| abstractGer |
Colorectal cancer (CRC) incidence changes with time and by variations in diet and lifestyle, as evidenced historically by migrant studies and recently by extensive epidemiologic evidence. The worldwide heterogeneity in CRC incidence is strongly suggestive of etiological involvement of environmental exposures, particularly lifestyle and diet. It is established that physical inactivity, obesity and some dietary factors (red/processed meats, alcohol) are positively associated with CRC, while healthy lifestyle habits show inverse associations. Mechanistic evidence shows that lifestyle and dietary components that contribute to energy excess are linked with increased CRC via metabolic dysfunction, inflammation, oxidative stress, bacterial dysbiosis and breakdown of gut barrier integrity while the reverse is apparent for components associated with decreased risk. This chapter will review the available evidence on lifestyle and dietary factors in CRC etiology and their underlying mechanisms in CRC development. This short review will also touch upon available information on potential gene-environment interactions, molecular sub-types of CRC and anatomical sub-sites within the colorectum. |
| abstract_unstemmed |
Colorectal cancer (CRC) incidence changes with time and by variations in diet and lifestyle, as evidenced historically by migrant studies and recently by extensive epidemiologic evidence. The worldwide heterogeneity in CRC incidence is strongly suggestive of etiological involvement of environmental exposures, particularly lifestyle and diet. It is established that physical inactivity, obesity and some dietary factors (red/processed meats, alcohol) are positively associated with CRC, while healthy lifestyle habits show inverse associations. Mechanistic evidence shows that lifestyle and dietary components that contribute to energy excess are linked with increased CRC via metabolic dysfunction, inflammation, oxidative stress, bacterial dysbiosis and breakdown of gut barrier integrity while the reverse is apparent for components associated with decreased risk. This chapter will review the available evidence on lifestyle and dietary factors in CRC etiology and their underlying mechanisms in CRC development. This short review will also touch upon available information on potential gene-environment interactions, molecular sub-types of CRC and anatomical sub-sites within the colorectum. |
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Lifestyle and dietary environmental factors in colorectal cancer susceptibility |
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Moreno, Victor Hughes, David J. Vodicka, Ludmila Vodicka, Pavel Aglago, Elom K. Gunter, Marc J. Jenab, Mazda |
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