Hepatitis B and D
Chronic hepatitis B (CHB) remains a major global healthcare challenge with changing epidemiology and increasing morbidity and mortality from the complications of liver cirrhosis and hepatocellular carcinoma (HCC). Hepatitis B virus infection can be broadly categorized into four disease phases: (1) h...
Ausführliche Beschreibung
Autor*in: |
Koffas, Apostolos [verfasserIn] Kennedy, Patrick T. [verfasserIn] |
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Format: |
E-Artikel |
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Sprache: |
Englisch |
Erschienen: |
2019 |
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Schlagwörter: |
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Übergeordnetes Werk: |
Enthalten in: Medicine - [Oxford] : Elsevier, 2002, 47, Seite 746-751 |
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Übergeordnetes Werk: |
volume:47 ; pages:746-751 |
DOI / URN: |
10.1016/j.mpmed.2019.08.004 |
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Katalog-ID: |
ELV003116638 |
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520 | |a Chronic hepatitis B (CHB) remains a major global healthcare challenge with changing epidemiology and increasing morbidity and mortality from the complications of liver cirrhosis and hepatocellular carcinoma (HCC). Hepatitis B virus infection can be broadly categorized into four disease phases: (1) hepatitis B e antigen (HBeAg)-positive chronic infection; (2) HBeAg-positive chronic hepatitis; (3) HBeAg-negative chronic infection; and (4) HBeAg-negative chronic hepatitis. After hepatitis B surface antigen loss, patients do not require any specific follow-up but they carry a risk of reactivation in the event of immunosuppression. The primary treatment goal in CHB is to improve survival and quality of life by preventing disease progression and the development of HCC. Current treatment regimens are non-curative and, once initiated, treatment is usually of indefinite duration. Treatment decisions are made on the basis of disease assessment and risk stratification. All CHB patients, including those on treatment, should be monitored for disease progression and HCC development. Hepatitis B virus/D virus co-infection represents the most severe form of chronic viral hepatitis because of more rapid disease progression and increased risk of cirrhosis and HCC; thus it requires special consideration. In the present review, we summarize the guidance on hepatitis B and D diagnosis and treatment. | ||
650 | 4 | |a Chronic hepatitis B | |
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650 | 4 | |a hepatitis D virus infection | |
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allfields |
10.1016/j.mpmed.2019.08.004 doi (DE-627)ELV003116638 (ELSEVIER)S1357-3039(19)30203-8 DE-627 ger DE-627 rda eng 610 DE-600 44.00 bkl Koffas, Apostolos verfasserin aut Hepatitis B and D 2019 nicht spezifiziert zzz rdacontent Computermedien c rdamedia Online-Ressource cr rdacarrier Chronic hepatitis B (CHB) remains a major global healthcare challenge with changing epidemiology and increasing morbidity and mortality from the complications of liver cirrhosis and hepatocellular carcinoma (HCC). Hepatitis B virus infection can be broadly categorized into four disease phases: (1) hepatitis B e antigen (HBeAg)-positive chronic infection; (2) HBeAg-positive chronic hepatitis; (3) HBeAg-negative chronic infection; and (4) HBeAg-negative chronic hepatitis. After hepatitis B surface antigen loss, patients do not require any specific follow-up but they carry a risk of reactivation in the event of immunosuppression. The primary treatment goal in CHB is to improve survival and quality of life by preventing disease progression and the development of HCC. Current treatment regimens are non-curative and, once initiated, treatment is usually of indefinite duration. Treatment decisions are made on the basis of disease assessment and risk stratification. All CHB patients, including those on treatment, should be monitored for disease progression and HCC development. Hepatitis B virus/D virus co-infection represents the most severe form of chronic viral hepatitis because of more rapid disease progression and increased risk of cirrhosis and HCC; thus it requires special consideration. In the present review, we summarize the guidance on hepatitis B and D diagnosis and treatment. Chronic hepatitis B hepatitis B virus infection hepatitis D virus infection Kennedy, Patrick T. verfasserin aut Enthalten in Medicine [Oxford] : Elsevier, 2002 47, Seite 746-751 (DE-627)362773971 (DE-600)2100582-5 (DE-576)271585617 1878-9390 nnns volume:47 pages:746-751 GBV_USEFLAG_U SYSFLAG_U GBV_ELV SSG-OLC-PHA GBV_ILN_20 GBV_ILN_22 GBV_ILN_23 GBV_ILN_24 GBV_ILN_31 GBV_ILN_32 GBV_ILN_40 GBV_ILN_60 GBV_ILN_62 GBV_ILN_63 GBV_ILN_65 GBV_ILN_69 GBV_ILN_70 GBV_ILN_73 GBV_ILN_74 GBV_ILN_90 GBV_ILN_95 GBV_ILN_100 GBV_ILN_101 GBV_ILN_105 GBV_ILN_110 GBV_ILN_151 GBV_ILN_224 GBV_ILN_370 GBV_ILN_602 GBV_ILN_702 GBV_ILN_2001 GBV_ILN_2003 GBV_ILN_2004 GBV_ILN_2005 GBV_ILN_2006 GBV_ILN_2008 GBV_ILN_2011 GBV_ILN_2014 GBV_ILN_2015 GBV_ILN_2020 GBV_ILN_2021 GBV_ILN_2025 GBV_ILN_2026 GBV_ILN_2027 GBV_ILN_2034 GBV_ILN_2038 GBV_ILN_2044 GBV_ILN_2048 GBV_ILN_2049 GBV_ILN_2050 GBV_ILN_2055 GBV_ILN_2056 GBV_ILN_2059 GBV_ILN_2061 GBV_ILN_2064 GBV_ILN_2065 GBV_ILN_2068 GBV_ILN_2088 GBV_ILN_2111 GBV_ILN_2112 GBV_ILN_2113 GBV_ILN_2118 GBV_ILN_2122 GBV_ILN_2129 GBV_ILN_2143 GBV_ILN_2147 GBV_ILN_2148 GBV_ILN_2152 GBV_ILN_2153 GBV_ILN_2190 GBV_ILN_2232 GBV_ILN_2336 GBV_ILN_2470 GBV_ILN_2507 GBV_ILN_2522 GBV_ILN_4035 GBV_ILN_4037 GBV_ILN_4046 GBV_ILN_4112 GBV_ILN_4125 GBV_ILN_4126 GBV_ILN_4242 GBV_ILN_4251 GBV_ILN_4305 GBV_ILN_4313 GBV_ILN_4322 GBV_ILN_4323 GBV_ILN_4324 GBV_ILN_4325 GBV_ILN_4326 GBV_ILN_4333 GBV_ILN_4334 GBV_ILN_4335 GBV_ILN_4338 GBV_ILN_4393 44.00 Medizin: Allgemeines AR 47 746-751 |
spelling |
10.1016/j.mpmed.2019.08.004 doi (DE-627)ELV003116638 (ELSEVIER)S1357-3039(19)30203-8 DE-627 ger DE-627 rda eng 610 DE-600 44.00 bkl Koffas, Apostolos verfasserin aut Hepatitis B and D 2019 nicht spezifiziert zzz rdacontent Computermedien c rdamedia Online-Ressource cr rdacarrier Chronic hepatitis B (CHB) remains a major global healthcare challenge with changing epidemiology and increasing morbidity and mortality from the complications of liver cirrhosis and hepatocellular carcinoma (HCC). Hepatitis B virus infection can be broadly categorized into four disease phases: (1) hepatitis B e antigen (HBeAg)-positive chronic infection; (2) HBeAg-positive chronic hepatitis; (3) HBeAg-negative chronic infection; and (4) HBeAg-negative chronic hepatitis. After hepatitis B surface antigen loss, patients do not require any specific follow-up but they carry a risk of reactivation in the event of immunosuppression. The primary treatment goal in CHB is to improve survival and quality of life by preventing disease progression and the development of HCC. Current treatment regimens are non-curative and, once initiated, treatment is usually of indefinite duration. Treatment decisions are made on the basis of disease assessment and risk stratification. All CHB patients, including those on treatment, should be monitored for disease progression and HCC development. Hepatitis B virus/D virus co-infection represents the most severe form of chronic viral hepatitis because of more rapid disease progression and increased risk of cirrhosis and HCC; thus it requires special consideration. In the present review, we summarize the guidance on hepatitis B and D diagnosis and treatment. Chronic hepatitis B hepatitis B virus infection hepatitis D virus infection Kennedy, Patrick T. verfasserin aut Enthalten in Medicine [Oxford] : Elsevier, 2002 47, Seite 746-751 (DE-627)362773971 (DE-600)2100582-5 (DE-576)271585617 1878-9390 nnns volume:47 pages:746-751 GBV_USEFLAG_U SYSFLAG_U GBV_ELV SSG-OLC-PHA GBV_ILN_20 GBV_ILN_22 GBV_ILN_23 GBV_ILN_24 GBV_ILN_31 GBV_ILN_32 GBV_ILN_40 GBV_ILN_60 GBV_ILN_62 GBV_ILN_63 GBV_ILN_65 GBV_ILN_69 GBV_ILN_70 GBV_ILN_73 GBV_ILN_74 GBV_ILN_90 GBV_ILN_95 GBV_ILN_100 GBV_ILN_101 GBV_ILN_105 GBV_ILN_110 GBV_ILN_151 GBV_ILN_224 GBV_ILN_370 GBV_ILN_602 GBV_ILN_702 GBV_ILN_2001 GBV_ILN_2003 GBV_ILN_2004 GBV_ILN_2005 GBV_ILN_2006 GBV_ILN_2008 GBV_ILN_2011 GBV_ILN_2014 GBV_ILN_2015 GBV_ILN_2020 GBV_ILN_2021 GBV_ILN_2025 GBV_ILN_2026 GBV_ILN_2027 GBV_ILN_2034 GBV_ILN_2038 GBV_ILN_2044 GBV_ILN_2048 GBV_ILN_2049 GBV_ILN_2050 GBV_ILN_2055 GBV_ILN_2056 GBV_ILN_2059 GBV_ILN_2061 GBV_ILN_2064 GBV_ILN_2065 GBV_ILN_2068 GBV_ILN_2088 GBV_ILN_2111 GBV_ILN_2112 GBV_ILN_2113 GBV_ILN_2118 GBV_ILN_2122 GBV_ILN_2129 GBV_ILN_2143 GBV_ILN_2147 GBV_ILN_2148 GBV_ILN_2152 GBV_ILN_2153 GBV_ILN_2190 GBV_ILN_2232 GBV_ILN_2336 GBV_ILN_2470 GBV_ILN_2507 GBV_ILN_2522 GBV_ILN_4035 GBV_ILN_4037 GBV_ILN_4046 GBV_ILN_4112 GBV_ILN_4125 GBV_ILN_4126 GBV_ILN_4242 GBV_ILN_4251 GBV_ILN_4305 GBV_ILN_4313 GBV_ILN_4322 GBV_ILN_4323 GBV_ILN_4324 GBV_ILN_4325 GBV_ILN_4326 GBV_ILN_4333 GBV_ILN_4334 GBV_ILN_4335 GBV_ILN_4338 GBV_ILN_4393 44.00 Medizin: Allgemeines AR 47 746-751 |
allfields_unstemmed |
10.1016/j.mpmed.2019.08.004 doi (DE-627)ELV003116638 (ELSEVIER)S1357-3039(19)30203-8 DE-627 ger DE-627 rda eng 610 DE-600 44.00 bkl Koffas, Apostolos verfasserin aut Hepatitis B and D 2019 nicht spezifiziert zzz rdacontent Computermedien c rdamedia Online-Ressource cr rdacarrier Chronic hepatitis B (CHB) remains a major global healthcare challenge with changing epidemiology and increasing morbidity and mortality from the complications of liver cirrhosis and hepatocellular carcinoma (HCC). Hepatitis B virus infection can be broadly categorized into four disease phases: (1) hepatitis B e antigen (HBeAg)-positive chronic infection; (2) HBeAg-positive chronic hepatitis; (3) HBeAg-negative chronic infection; and (4) HBeAg-negative chronic hepatitis. After hepatitis B surface antigen loss, patients do not require any specific follow-up but they carry a risk of reactivation in the event of immunosuppression. The primary treatment goal in CHB is to improve survival and quality of life by preventing disease progression and the development of HCC. Current treatment regimens are non-curative and, once initiated, treatment is usually of indefinite duration. Treatment decisions are made on the basis of disease assessment and risk stratification. All CHB patients, including those on treatment, should be monitored for disease progression and HCC development. Hepatitis B virus/D virus co-infection represents the most severe form of chronic viral hepatitis because of more rapid disease progression and increased risk of cirrhosis and HCC; thus it requires special consideration. In the present review, we summarize the guidance on hepatitis B and D diagnosis and treatment. Chronic hepatitis B hepatitis B virus infection hepatitis D virus infection Kennedy, Patrick T. verfasserin aut Enthalten in Medicine [Oxford] : Elsevier, 2002 47, Seite 746-751 (DE-627)362773971 (DE-600)2100582-5 (DE-576)271585617 1878-9390 nnns volume:47 pages:746-751 GBV_USEFLAG_U SYSFLAG_U GBV_ELV SSG-OLC-PHA GBV_ILN_20 GBV_ILN_22 GBV_ILN_23 GBV_ILN_24 GBV_ILN_31 GBV_ILN_32 GBV_ILN_40 GBV_ILN_60 GBV_ILN_62 GBV_ILN_63 GBV_ILN_65 GBV_ILN_69 GBV_ILN_70 GBV_ILN_73 GBV_ILN_74 GBV_ILN_90 GBV_ILN_95 GBV_ILN_100 GBV_ILN_101 GBV_ILN_105 GBV_ILN_110 GBV_ILN_151 GBV_ILN_224 GBV_ILN_370 GBV_ILN_602 GBV_ILN_702 GBV_ILN_2001 GBV_ILN_2003 GBV_ILN_2004 GBV_ILN_2005 GBV_ILN_2006 GBV_ILN_2008 GBV_ILN_2011 GBV_ILN_2014 GBV_ILN_2015 GBV_ILN_2020 GBV_ILN_2021 GBV_ILN_2025 GBV_ILN_2026 GBV_ILN_2027 GBV_ILN_2034 GBV_ILN_2038 GBV_ILN_2044 GBV_ILN_2048 GBV_ILN_2049 GBV_ILN_2050 GBV_ILN_2055 GBV_ILN_2056 GBV_ILN_2059 GBV_ILN_2061 GBV_ILN_2064 GBV_ILN_2065 GBV_ILN_2068 GBV_ILN_2088 GBV_ILN_2111 GBV_ILN_2112 GBV_ILN_2113 GBV_ILN_2118 GBV_ILN_2122 GBV_ILN_2129 GBV_ILN_2143 GBV_ILN_2147 GBV_ILN_2148 GBV_ILN_2152 GBV_ILN_2153 GBV_ILN_2190 GBV_ILN_2232 GBV_ILN_2336 GBV_ILN_2470 GBV_ILN_2507 GBV_ILN_2522 GBV_ILN_4035 GBV_ILN_4037 GBV_ILN_4046 GBV_ILN_4112 GBV_ILN_4125 GBV_ILN_4126 GBV_ILN_4242 GBV_ILN_4251 GBV_ILN_4305 GBV_ILN_4313 GBV_ILN_4322 GBV_ILN_4323 GBV_ILN_4324 GBV_ILN_4325 GBV_ILN_4326 GBV_ILN_4333 GBV_ILN_4334 GBV_ILN_4335 GBV_ILN_4338 GBV_ILN_4393 44.00 Medizin: Allgemeines AR 47 746-751 |
allfieldsGer |
10.1016/j.mpmed.2019.08.004 doi (DE-627)ELV003116638 (ELSEVIER)S1357-3039(19)30203-8 DE-627 ger DE-627 rda eng 610 DE-600 44.00 bkl Koffas, Apostolos verfasserin aut Hepatitis B and D 2019 nicht spezifiziert zzz rdacontent Computermedien c rdamedia Online-Ressource cr rdacarrier Chronic hepatitis B (CHB) remains a major global healthcare challenge with changing epidemiology and increasing morbidity and mortality from the complications of liver cirrhosis and hepatocellular carcinoma (HCC). Hepatitis B virus infection can be broadly categorized into four disease phases: (1) hepatitis B e antigen (HBeAg)-positive chronic infection; (2) HBeAg-positive chronic hepatitis; (3) HBeAg-negative chronic infection; and (4) HBeAg-negative chronic hepatitis. After hepatitis B surface antigen loss, patients do not require any specific follow-up but they carry a risk of reactivation in the event of immunosuppression. The primary treatment goal in CHB is to improve survival and quality of life by preventing disease progression and the development of HCC. Current treatment regimens are non-curative and, once initiated, treatment is usually of indefinite duration. Treatment decisions are made on the basis of disease assessment and risk stratification. All CHB patients, including those on treatment, should be monitored for disease progression and HCC development. Hepatitis B virus/D virus co-infection represents the most severe form of chronic viral hepatitis because of more rapid disease progression and increased risk of cirrhosis and HCC; thus it requires special consideration. In the present review, we summarize the guidance on hepatitis B and D diagnosis and treatment. Chronic hepatitis B hepatitis B virus infection hepatitis D virus infection Kennedy, Patrick T. verfasserin aut Enthalten in Medicine [Oxford] : Elsevier, 2002 47, Seite 746-751 (DE-627)362773971 (DE-600)2100582-5 (DE-576)271585617 1878-9390 nnns volume:47 pages:746-751 GBV_USEFLAG_U SYSFLAG_U GBV_ELV SSG-OLC-PHA GBV_ILN_20 GBV_ILN_22 GBV_ILN_23 GBV_ILN_24 GBV_ILN_31 GBV_ILN_32 GBV_ILN_40 GBV_ILN_60 GBV_ILN_62 GBV_ILN_63 GBV_ILN_65 GBV_ILN_69 GBV_ILN_70 GBV_ILN_73 GBV_ILN_74 GBV_ILN_90 GBV_ILN_95 GBV_ILN_100 GBV_ILN_101 GBV_ILN_105 GBV_ILN_110 GBV_ILN_151 GBV_ILN_224 GBV_ILN_370 GBV_ILN_602 GBV_ILN_702 GBV_ILN_2001 GBV_ILN_2003 GBV_ILN_2004 GBV_ILN_2005 GBV_ILN_2006 GBV_ILN_2008 GBV_ILN_2011 GBV_ILN_2014 GBV_ILN_2015 GBV_ILN_2020 GBV_ILN_2021 GBV_ILN_2025 GBV_ILN_2026 GBV_ILN_2027 GBV_ILN_2034 GBV_ILN_2038 GBV_ILN_2044 GBV_ILN_2048 GBV_ILN_2049 GBV_ILN_2050 GBV_ILN_2055 GBV_ILN_2056 GBV_ILN_2059 GBV_ILN_2061 GBV_ILN_2064 GBV_ILN_2065 GBV_ILN_2068 GBV_ILN_2088 GBV_ILN_2111 GBV_ILN_2112 GBV_ILN_2113 GBV_ILN_2118 GBV_ILN_2122 GBV_ILN_2129 GBV_ILN_2143 GBV_ILN_2147 GBV_ILN_2148 GBV_ILN_2152 GBV_ILN_2153 GBV_ILN_2190 GBV_ILN_2232 GBV_ILN_2336 GBV_ILN_2470 GBV_ILN_2507 GBV_ILN_2522 GBV_ILN_4035 GBV_ILN_4037 GBV_ILN_4046 GBV_ILN_4112 GBV_ILN_4125 GBV_ILN_4126 GBV_ILN_4242 GBV_ILN_4251 GBV_ILN_4305 GBV_ILN_4313 GBV_ILN_4322 GBV_ILN_4323 GBV_ILN_4324 GBV_ILN_4325 GBV_ILN_4326 GBV_ILN_4333 GBV_ILN_4334 GBV_ILN_4335 GBV_ILN_4338 GBV_ILN_4393 44.00 Medizin: Allgemeines AR 47 746-751 |
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10.1016/j.mpmed.2019.08.004 doi (DE-627)ELV003116638 (ELSEVIER)S1357-3039(19)30203-8 DE-627 ger DE-627 rda eng 610 DE-600 44.00 bkl Koffas, Apostolos verfasserin aut Hepatitis B and D 2019 nicht spezifiziert zzz rdacontent Computermedien c rdamedia Online-Ressource cr rdacarrier Chronic hepatitis B (CHB) remains a major global healthcare challenge with changing epidemiology and increasing morbidity and mortality from the complications of liver cirrhosis and hepatocellular carcinoma (HCC). Hepatitis B virus infection can be broadly categorized into four disease phases: (1) hepatitis B e antigen (HBeAg)-positive chronic infection; (2) HBeAg-positive chronic hepatitis; (3) HBeAg-negative chronic infection; and (4) HBeAg-negative chronic hepatitis. After hepatitis B surface antigen loss, patients do not require any specific follow-up but they carry a risk of reactivation in the event of immunosuppression. The primary treatment goal in CHB is to improve survival and quality of life by preventing disease progression and the development of HCC. Current treatment regimens are non-curative and, once initiated, treatment is usually of indefinite duration. Treatment decisions are made on the basis of disease assessment and risk stratification. All CHB patients, including those on treatment, should be monitored for disease progression and HCC development. Hepatitis B virus/D virus co-infection represents the most severe form of chronic viral hepatitis because of more rapid disease progression and increased risk of cirrhosis and HCC; thus it requires special consideration. In the present review, we summarize the guidance on hepatitis B and D diagnosis and treatment. Chronic hepatitis B hepatitis B virus infection hepatitis D virus infection Kennedy, Patrick T. verfasserin aut Enthalten in Medicine [Oxford] : Elsevier, 2002 47, Seite 746-751 (DE-627)362773971 (DE-600)2100582-5 (DE-576)271585617 1878-9390 nnns volume:47 pages:746-751 GBV_USEFLAG_U SYSFLAG_U GBV_ELV SSG-OLC-PHA GBV_ILN_20 GBV_ILN_22 GBV_ILN_23 GBV_ILN_24 GBV_ILN_31 GBV_ILN_32 GBV_ILN_40 GBV_ILN_60 GBV_ILN_62 GBV_ILN_63 GBV_ILN_65 GBV_ILN_69 GBV_ILN_70 GBV_ILN_73 GBV_ILN_74 GBV_ILN_90 GBV_ILN_95 GBV_ILN_100 GBV_ILN_101 GBV_ILN_105 GBV_ILN_110 GBV_ILN_151 GBV_ILN_224 GBV_ILN_370 GBV_ILN_602 GBV_ILN_702 GBV_ILN_2001 GBV_ILN_2003 GBV_ILN_2004 GBV_ILN_2005 GBV_ILN_2006 GBV_ILN_2008 GBV_ILN_2011 GBV_ILN_2014 GBV_ILN_2015 GBV_ILN_2020 GBV_ILN_2021 GBV_ILN_2025 GBV_ILN_2026 GBV_ILN_2027 GBV_ILN_2034 GBV_ILN_2038 GBV_ILN_2044 GBV_ILN_2048 GBV_ILN_2049 GBV_ILN_2050 GBV_ILN_2055 GBV_ILN_2056 GBV_ILN_2059 GBV_ILN_2061 GBV_ILN_2064 GBV_ILN_2065 GBV_ILN_2068 GBV_ILN_2088 GBV_ILN_2111 GBV_ILN_2112 GBV_ILN_2113 GBV_ILN_2118 GBV_ILN_2122 GBV_ILN_2129 GBV_ILN_2143 GBV_ILN_2147 GBV_ILN_2148 GBV_ILN_2152 GBV_ILN_2153 GBV_ILN_2190 GBV_ILN_2232 GBV_ILN_2336 GBV_ILN_2470 GBV_ILN_2507 GBV_ILN_2522 GBV_ILN_4035 GBV_ILN_4037 GBV_ILN_4046 GBV_ILN_4112 GBV_ILN_4125 GBV_ILN_4126 GBV_ILN_4242 GBV_ILN_4251 GBV_ILN_4305 GBV_ILN_4313 GBV_ILN_4322 GBV_ILN_4323 GBV_ILN_4324 GBV_ILN_4325 GBV_ILN_4326 GBV_ILN_4333 GBV_ILN_4334 GBV_ILN_4335 GBV_ILN_4338 GBV_ILN_4393 44.00 Medizin: Allgemeines AR 47 746-751 |
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Hepatitis B and D |
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Koffas, Apostolos |
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Koffas, Apostolos Kennedy, Patrick T. |
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Elektronische Aufsätze |
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Koffas, Apostolos |
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10.1016/j.mpmed.2019.08.004 |
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610 |
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verfasserin |
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hepatitis b and d |
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Hepatitis B and D |
abstract |
Chronic hepatitis B (CHB) remains a major global healthcare challenge with changing epidemiology and increasing morbidity and mortality from the complications of liver cirrhosis and hepatocellular carcinoma (HCC). Hepatitis B virus infection can be broadly categorized into four disease phases: (1) hepatitis B e antigen (HBeAg)-positive chronic infection; (2) HBeAg-positive chronic hepatitis; (3) HBeAg-negative chronic infection; and (4) HBeAg-negative chronic hepatitis. After hepatitis B surface antigen loss, patients do not require any specific follow-up but they carry a risk of reactivation in the event of immunosuppression. The primary treatment goal in CHB is to improve survival and quality of life by preventing disease progression and the development of HCC. Current treatment regimens are non-curative and, once initiated, treatment is usually of indefinite duration. Treatment decisions are made on the basis of disease assessment and risk stratification. All CHB patients, including those on treatment, should be monitored for disease progression and HCC development. Hepatitis B virus/D virus co-infection represents the most severe form of chronic viral hepatitis because of more rapid disease progression and increased risk of cirrhosis and HCC; thus it requires special consideration. In the present review, we summarize the guidance on hepatitis B and D diagnosis and treatment. |
abstractGer |
Chronic hepatitis B (CHB) remains a major global healthcare challenge with changing epidemiology and increasing morbidity and mortality from the complications of liver cirrhosis and hepatocellular carcinoma (HCC). Hepatitis B virus infection can be broadly categorized into four disease phases: (1) hepatitis B e antigen (HBeAg)-positive chronic infection; (2) HBeAg-positive chronic hepatitis; (3) HBeAg-negative chronic infection; and (4) HBeAg-negative chronic hepatitis. After hepatitis B surface antigen loss, patients do not require any specific follow-up but they carry a risk of reactivation in the event of immunosuppression. The primary treatment goal in CHB is to improve survival and quality of life by preventing disease progression and the development of HCC. Current treatment regimens are non-curative and, once initiated, treatment is usually of indefinite duration. Treatment decisions are made on the basis of disease assessment and risk stratification. All CHB patients, including those on treatment, should be monitored for disease progression and HCC development. Hepatitis B virus/D virus co-infection represents the most severe form of chronic viral hepatitis because of more rapid disease progression and increased risk of cirrhosis and HCC; thus it requires special consideration. In the present review, we summarize the guidance on hepatitis B and D diagnosis and treatment. |
abstract_unstemmed |
Chronic hepatitis B (CHB) remains a major global healthcare challenge with changing epidemiology and increasing morbidity and mortality from the complications of liver cirrhosis and hepatocellular carcinoma (HCC). Hepatitis B virus infection can be broadly categorized into four disease phases: (1) hepatitis B e antigen (HBeAg)-positive chronic infection; (2) HBeAg-positive chronic hepatitis; (3) HBeAg-negative chronic infection; and (4) HBeAg-negative chronic hepatitis. After hepatitis B surface antigen loss, patients do not require any specific follow-up but they carry a risk of reactivation in the event of immunosuppression. The primary treatment goal in CHB is to improve survival and quality of life by preventing disease progression and the development of HCC. Current treatment regimens are non-curative and, once initiated, treatment is usually of indefinite duration. Treatment decisions are made on the basis of disease assessment and risk stratification. All CHB patients, including those on treatment, should be monitored for disease progression and HCC development. Hepatitis B virus/D virus co-infection represents the most severe form of chronic viral hepatitis because of more rapid disease progression and increased risk of cirrhosis and HCC; thus it requires special consideration. In the present review, we summarize the guidance on hepatitis B and D diagnosis and treatment. |
collection_details |
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title_short |
Hepatitis B and D |
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up_date |
2024-07-06T18:32:46.558Z |
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