Effect of lung protective ventilation on perioperative pulmonary infection in elderly patients with mild to moderate COPD under general anesthesia
Objective: The research aims to explore the effects of different ventilation time on postoperative pulmonary infection in elderly patients with the mild and moderate chronic pulmonary obstructive disease (COPD), so as to provide evidence for reducing postoperative pulmonary infection complications i...
Ausführliche Beschreibung
Gespeichert in:
| Autor*in: |
Ji, Xiaochen [verfasserIn] Cui, Wenbin [verfasserIn] Zhang, Boya [verfasserIn] Shan, Shiqiang [verfasserIn] |
|---|
| Format: |
E-Artikel |
|---|---|
| Sprache: |
Englisch |
| Erschienen: |
2019 |
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| Schlagwörter: |
Chronic obstructive pulmonary disease |
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| Übergeordnetes Werk: |
Enthalten in: Journal of infection and public health - Amsterdam [u.a.] : Elsevier, 2008, 13, Seite 281-286 |
|---|---|
| Übergeordnetes Werk: |
volume:13 ; pages:281-286 |
| DOI / URN: |
10.1016/j.jiph.2019.11.021 |
|---|
| Katalog-ID: |
ELV003604837 |
|---|
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| 245 | 1 | 0 | |a Effect of lung protective ventilation on perioperative pulmonary infection in elderly patients with mild to moderate COPD under general anesthesia |
| 264 | 1 | |c 2019 | |
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| 520 | |a Objective: The research aims to explore the effects of different ventilation time on postoperative pulmonary infection in elderly patients with the mild and moderate chronic pulmonary obstructive disease (COPD), so as to provide evidence for reducing postoperative pulmonary infection complications in patients with COPD.Methods: 120 elderly patients with mild and moderate COPD were selected as the research objects. First, the general information of patients with COPD before surgery and the difference between healthy population and lung forced expiratory volume in 1s (FEV1), forced vital capacity (FVC), FEV1/FVC and maximum midexpiratory flow (MMEF) functional indexes were analyzed and detected. Patients with COPD were operated on with single lung ventilation and general anesthesia. Patients with mild and moderate COPD were divided into two groups according to lung ventilation time (ventilation time 1.0–2.0h group, ventilation time >2.0h group). The inflammatory factors of IL-6, IL-21, TNF-α, and CXCL13 as well as inflammatory indicators of polycaprolactam (PCT), C-reactive protein (CRP) and white blood cell (WBC) in serum of all patients were detected after the operation. The probability of pulmonary infection after COPD was diagnosed and analyzed. Finally, the regression analysis of postoperative pulmonary infection in COPD patients was analyzed.Results: (1) The results showed that the smoking rate of mild and COPD patients was significantly higher than that of healthy people (P<0.05). (2) The lung function indexes of the mild and moderate groups were significantly lower than those of the control group (P<0.01), while the lung function indexes of the moderate group were significantly lower than those of the mild group (P<0.05). (3) All the inflammatory indicators of moderate COPD patients were significantly higher than those of mild COPD patients (P<0.05). (4) All inflammation-related indicators in patients with mild and moderate COPD with ventilation time of >2.0h were significantly higher than those in the 1.0–2.0h group (P<0.05). (5) The probability of postoperative pulmonary infection in moderate patients was significantly higher than that in mild patients (P<0.01). The probability of postoperative pulmonary infection in >2.0h group was significantly higher than that in the 1.0–2.0h group (P<0.01). (6) Multivariate Logistic regression analysis results showed that lung function, duration of lung ventilation and smoking were independent risk factors for postoperative pulmonary infection in COPD patients.Conclusion: It is important to detect pulmonary function before surgery, maintain single lung ventilation protection for no more than 2.0h during surgery, and quit smoking to improve pulmonary infection in patients with COPD after surgery. In addition, the incidence of postoperative pulmonary infection in patients with moderate COPD was higher than that in patients with mild COPD, suggesting that early treatment in patients with COPD was also of great significance in reducing the incidence of postoperative pulmonary infection. | ||
| 650 | 4 | |a Chronic obstructive pulmonary disease | |
| 650 | 4 | |a General anesthesia for single-lung ventilation | |
| 650 | 4 | |a Elderly patients | |
| 650 | 4 | |a Perioperative period | |
| 650 | 4 | |a Duration of lung ventilation | |
| 700 | 1 | |a Cui, Wenbin |e verfasserin |4 aut | |
| 700 | 1 | |a Zhang, Boya |e verfasserin |4 aut | |
| 700 | 1 | |a Shan, Shiqiang |e verfasserin |4 aut | |
| 773 | 0 | 8 | |i Enthalten in |t Journal of infection and public health |d Amsterdam [u.a.] : Elsevier, 2008 |g 13, Seite 281-286 |h Online-Ressource |w (DE-627)587140267 |w (DE-600)2467587-8 |w (DE-576)302178457 |x 1876-035X |7 nnns |
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10.1016/j.jiph.2019.11.021 doi (DE-627)ELV003604837 (ELSEVIER)S1876-0341(19)30366-1 DE-627 ger DE-627 rda eng 610 DE-600 44.75 bkl Ji, Xiaochen verfasserin aut Effect of lung protective ventilation on perioperative pulmonary infection in elderly patients with mild to moderate COPD under general anesthesia 2019 nicht spezifiziert zzz rdacontent Computermedien c rdamedia Online-Ressource cr rdacarrier Objective: The research aims to explore the effects of different ventilation time on postoperative pulmonary infection in elderly patients with the mild and moderate chronic pulmonary obstructive disease (COPD), so as to provide evidence for reducing postoperative pulmonary infection complications in patients with COPD.Methods: 120 elderly patients with mild and moderate COPD were selected as the research objects. First, the general information of patients with COPD before surgery and the difference between healthy population and lung forced expiratory volume in 1s (FEV1), forced vital capacity (FVC), FEV1/FVC and maximum midexpiratory flow (MMEF) functional indexes were analyzed and detected. Patients with COPD were operated on with single lung ventilation and general anesthesia. Patients with mild and moderate COPD were divided into two groups according to lung ventilation time (ventilation time 1.0–2.0h group, ventilation time >2.0h group). The inflammatory factors of IL-6, IL-21, TNF-α, and CXCL13 as well as inflammatory indicators of polycaprolactam (PCT), C-reactive protein (CRP) and white blood cell (WBC) in serum of all patients were detected after the operation. The probability of pulmonary infection after COPD was diagnosed and analyzed. Finally, the regression analysis of postoperative pulmonary infection in COPD patients was analyzed.Results: (1) The results showed that the smoking rate of mild and COPD patients was significantly higher than that of healthy people (P<0.05). (2) The lung function indexes of the mild and moderate groups were significantly lower than those of the control group (P<0.01), while the lung function indexes of the moderate group were significantly lower than those of the mild group (P<0.05). (3) All the inflammatory indicators of moderate COPD patients were significantly higher than those of mild COPD patients (P<0.05). (4) All inflammation-related indicators in patients with mild and moderate COPD with ventilation time of >2.0h were significantly higher than those in the 1.0–2.0h group (P<0.05). (5) The probability of postoperative pulmonary infection in moderate patients was significantly higher than that in mild patients (P<0.01). The probability of postoperative pulmonary infection in >2.0h group was significantly higher than that in the 1.0–2.0h group (P<0.01). (6) Multivariate Logistic regression analysis results showed that lung function, duration of lung ventilation and smoking were independent risk factors for postoperative pulmonary infection in COPD patients.Conclusion: It is important to detect pulmonary function before surgery, maintain single lung ventilation protection for no more than 2.0h during surgery, and quit smoking to improve pulmonary infection in patients with COPD after surgery. In addition, the incidence of postoperative pulmonary infection in patients with moderate COPD was higher than that in patients with mild COPD, suggesting that early treatment in patients with COPD was also of great significance in reducing the incidence of postoperative pulmonary infection. Chronic obstructive pulmonary disease General anesthesia for single-lung ventilation Elderly patients Perioperative period Duration of lung ventilation Cui, Wenbin verfasserin aut Zhang, Boya verfasserin aut Shan, Shiqiang verfasserin aut Enthalten in Journal of infection and public health Amsterdam [u.a.] : Elsevier, 2008 13, Seite 281-286 Online-Ressource (DE-627)587140267 (DE-600)2467587-8 (DE-576)302178457 1876-035X nnns volume:13 pages:281-286 GBV_USEFLAG_U SYSFLAG_U GBV_ELV SSG-OLC-PHA GBV_ILN_20 GBV_ILN_22 GBV_ILN_23 GBV_ILN_24 GBV_ILN_31 GBV_ILN_39 GBV_ILN_40 GBV_ILN_60 GBV_ILN_62 GBV_ILN_63 GBV_ILN_65 GBV_ILN_69 GBV_ILN_73 GBV_ILN_74 GBV_ILN_95 GBV_ILN_100 GBV_ILN_105 GBV_ILN_110 GBV_ILN_151 GBV_ILN_161 GBV_ILN_170 GBV_ILN_206 GBV_ILN_213 GBV_ILN_224 GBV_ILN_230 GBV_ILN_285 GBV_ILN_293 GBV_ILN_602 GBV_ILN_647 GBV_ILN_2001 GBV_ILN_2003 GBV_ILN_2004 GBV_ILN_2005 GBV_ILN_2006 GBV_ILN_2007 GBV_ILN_2008 GBV_ILN_2009 GBV_ILN_2010 GBV_ILN_2011 GBV_ILN_2014 GBV_ILN_2015 GBV_ILN_2020 GBV_ILN_2021 GBV_ILN_2025 GBV_ILN_2026 GBV_ILN_2027 GBV_ILN_2034 GBV_ILN_2038 GBV_ILN_2044 GBV_ILN_2048 GBV_ILN_2049 GBV_ILN_2050 GBV_ILN_2055 GBV_ILN_2056 GBV_ILN_2059 GBV_ILN_2061 GBV_ILN_2064 GBV_ILN_2088 GBV_ILN_2106 GBV_ILN_2110 GBV_ILN_2112 GBV_ILN_2122 GBV_ILN_2129 GBV_ILN_2143 GBV_ILN_2152 GBV_ILN_2153 GBV_ILN_2190 GBV_ILN_2232 GBV_ILN_2470 GBV_ILN_2507 GBV_ILN_4012 GBV_ILN_4035 GBV_ILN_4037 GBV_ILN_4112 GBV_ILN_4125 GBV_ILN_4126 GBV_ILN_4242 GBV_ILN_4249 GBV_ILN_4251 GBV_ILN_4305 GBV_ILN_4306 GBV_ILN_4307 GBV_ILN_4313 GBV_ILN_4322 GBV_ILN_4323 GBV_ILN_4324 GBV_ILN_4325 GBV_ILN_4326 GBV_ILN_4333 GBV_ILN_4334 GBV_ILN_4338 GBV_ILN_4367 GBV_ILN_4393 GBV_ILN_4700 44.75 Infektionskrankheiten parasitäre Krankheiten Medizin AR 13 281-286 |
| spelling |
10.1016/j.jiph.2019.11.021 doi (DE-627)ELV003604837 (ELSEVIER)S1876-0341(19)30366-1 DE-627 ger DE-627 rda eng 610 DE-600 44.75 bkl Ji, Xiaochen verfasserin aut Effect of lung protective ventilation on perioperative pulmonary infection in elderly patients with mild to moderate COPD under general anesthesia 2019 nicht spezifiziert zzz rdacontent Computermedien c rdamedia Online-Ressource cr rdacarrier Objective: The research aims to explore the effects of different ventilation time on postoperative pulmonary infection in elderly patients with the mild and moderate chronic pulmonary obstructive disease (COPD), so as to provide evidence for reducing postoperative pulmonary infection complications in patients with COPD.Methods: 120 elderly patients with mild and moderate COPD were selected as the research objects. First, the general information of patients with COPD before surgery and the difference between healthy population and lung forced expiratory volume in 1s (FEV1), forced vital capacity (FVC), FEV1/FVC and maximum midexpiratory flow (MMEF) functional indexes were analyzed and detected. Patients with COPD were operated on with single lung ventilation and general anesthesia. Patients with mild and moderate COPD were divided into two groups according to lung ventilation time (ventilation time 1.0–2.0h group, ventilation time >2.0h group). The inflammatory factors of IL-6, IL-21, TNF-α, and CXCL13 as well as inflammatory indicators of polycaprolactam (PCT), C-reactive protein (CRP) and white blood cell (WBC) in serum of all patients were detected after the operation. The probability of pulmonary infection after COPD was diagnosed and analyzed. Finally, the regression analysis of postoperative pulmonary infection in COPD patients was analyzed.Results: (1) The results showed that the smoking rate of mild and COPD patients was significantly higher than that of healthy people (P<0.05). (2) The lung function indexes of the mild and moderate groups were significantly lower than those of the control group (P<0.01), while the lung function indexes of the moderate group were significantly lower than those of the mild group (P<0.05). (3) All the inflammatory indicators of moderate COPD patients were significantly higher than those of mild COPD patients (P<0.05). (4) All inflammation-related indicators in patients with mild and moderate COPD with ventilation time of >2.0h were significantly higher than those in the 1.0–2.0h group (P<0.05). (5) The probability of postoperative pulmonary infection in moderate patients was significantly higher than that in mild patients (P<0.01). The probability of postoperative pulmonary infection in >2.0h group was significantly higher than that in the 1.0–2.0h group (P<0.01). (6) Multivariate Logistic regression analysis results showed that lung function, duration of lung ventilation and smoking were independent risk factors for postoperative pulmonary infection in COPD patients.Conclusion: It is important to detect pulmonary function before surgery, maintain single lung ventilation protection for no more than 2.0h during surgery, and quit smoking to improve pulmonary infection in patients with COPD after surgery. In addition, the incidence of postoperative pulmonary infection in patients with moderate COPD was higher than that in patients with mild COPD, suggesting that early treatment in patients with COPD was also of great significance in reducing the incidence of postoperative pulmonary infection. Chronic obstructive pulmonary disease General anesthesia for single-lung ventilation Elderly patients Perioperative period Duration of lung ventilation Cui, Wenbin verfasserin aut Zhang, Boya verfasserin aut Shan, Shiqiang verfasserin aut Enthalten in Journal of infection and public health Amsterdam [u.a.] : Elsevier, 2008 13, Seite 281-286 Online-Ressource (DE-627)587140267 (DE-600)2467587-8 (DE-576)302178457 1876-035X nnns volume:13 pages:281-286 GBV_USEFLAG_U SYSFLAG_U GBV_ELV SSG-OLC-PHA GBV_ILN_20 GBV_ILN_22 GBV_ILN_23 GBV_ILN_24 GBV_ILN_31 GBV_ILN_39 GBV_ILN_40 GBV_ILN_60 GBV_ILN_62 GBV_ILN_63 GBV_ILN_65 GBV_ILN_69 GBV_ILN_73 GBV_ILN_74 GBV_ILN_95 GBV_ILN_100 GBV_ILN_105 GBV_ILN_110 GBV_ILN_151 GBV_ILN_161 GBV_ILN_170 GBV_ILN_206 GBV_ILN_213 GBV_ILN_224 GBV_ILN_230 GBV_ILN_285 GBV_ILN_293 GBV_ILN_602 GBV_ILN_647 GBV_ILN_2001 GBV_ILN_2003 GBV_ILN_2004 GBV_ILN_2005 GBV_ILN_2006 GBV_ILN_2007 GBV_ILN_2008 GBV_ILN_2009 GBV_ILN_2010 GBV_ILN_2011 GBV_ILN_2014 GBV_ILN_2015 GBV_ILN_2020 GBV_ILN_2021 GBV_ILN_2025 GBV_ILN_2026 GBV_ILN_2027 GBV_ILN_2034 GBV_ILN_2038 GBV_ILN_2044 GBV_ILN_2048 GBV_ILN_2049 GBV_ILN_2050 GBV_ILN_2055 GBV_ILN_2056 GBV_ILN_2059 GBV_ILN_2061 GBV_ILN_2064 GBV_ILN_2088 GBV_ILN_2106 GBV_ILN_2110 GBV_ILN_2112 GBV_ILN_2122 GBV_ILN_2129 GBV_ILN_2143 GBV_ILN_2152 GBV_ILN_2153 GBV_ILN_2190 GBV_ILN_2232 GBV_ILN_2470 GBV_ILN_2507 GBV_ILN_4012 GBV_ILN_4035 GBV_ILN_4037 GBV_ILN_4112 GBV_ILN_4125 GBV_ILN_4126 GBV_ILN_4242 GBV_ILN_4249 GBV_ILN_4251 GBV_ILN_4305 GBV_ILN_4306 GBV_ILN_4307 GBV_ILN_4313 GBV_ILN_4322 GBV_ILN_4323 GBV_ILN_4324 GBV_ILN_4325 GBV_ILN_4326 GBV_ILN_4333 GBV_ILN_4334 GBV_ILN_4338 GBV_ILN_4367 GBV_ILN_4393 GBV_ILN_4700 44.75 Infektionskrankheiten parasitäre Krankheiten Medizin AR 13 281-286 |
| allfields_unstemmed |
10.1016/j.jiph.2019.11.021 doi (DE-627)ELV003604837 (ELSEVIER)S1876-0341(19)30366-1 DE-627 ger DE-627 rda eng 610 DE-600 44.75 bkl Ji, Xiaochen verfasserin aut Effect of lung protective ventilation on perioperative pulmonary infection in elderly patients with mild to moderate COPD under general anesthesia 2019 nicht spezifiziert zzz rdacontent Computermedien c rdamedia Online-Ressource cr rdacarrier Objective: The research aims to explore the effects of different ventilation time on postoperative pulmonary infection in elderly patients with the mild and moderate chronic pulmonary obstructive disease (COPD), so as to provide evidence for reducing postoperative pulmonary infection complications in patients with COPD.Methods: 120 elderly patients with mild and moderate COPD were selected as the research objects. First, the general information of patients with COPD before surgery and the difference between healthy population and lung forced expiratory volume in 1s (FEV1), forced vital capacity (FVC), FEV1/FVC and maximum midexpiratory flow (MMEF) functional indexes were analyzed and detected. Patients with COPD were operated on with single lung ventilation and general anesthesia. Patients with mild and moderate COPD were divided into two groups according to lung ventilation time (ventilation time 1.0–2.0h group, ventilation time >2.0h group). The inflammatory factors of IL-6, IL-21, TNF-α, and CXCL13 as well as inflammatory indicators of polycaprolactam (PCT), C-reactive protein (CRP) and white blood cell (WBC) in serum of all patients were detected after the operation. The probability of pulmonary infection after COPD was diagnosed and analyzed. Finally, the regression analysis of postoperative pulmonary infection in COPD patients was analyzed.Results: (1) The results showed that the smoking rate of mild and COPD patients was significantly higher than that of healthy people (P<0.05). (2) The lung function indexes of the mild and moderate groups were significantly lower than those of the control group (P<0.01), while the lung function indexes of the moderate group were significantly lower than those of the mild group (P<0.05). (3) All the inflammatory indicators of moderate COPD patients were significantly higher than those of mild COPD patients (P<0.05). (4) All inflammation-related indicators in patients with mild and moderate COPD with ventilation time of >2.0h were significantly higher than those in the 1.0–2.0h group (P<0.05). (5) The probability of postoperative pulmonary infection in moderate patients was significantly higher than that in mild patients (P<0.01). The probability of postoperative pulmonary infection in >2.0h group was significantly higher than that in the 1.0–2.0h group (P<0.01). (6) Multivariate Logistic regression analysis results showed that lung function, duration of lung ventilation and smoking were independent risk factors for postoperative pulmonary infection in COPD patients.Conclusion: It is important to detect pulmonary function before surgery, maintain single lung ventilation protection for no more than 2.0h during surgery, and quit smoking to improve pulmonary infection in patients with COPD after surgery. In addition, the incidence of postoperative pulmonary infection in patients with moderate COPD was higher than that in patients with mild COPD, suggesting that early treatment in patients with COPD was also of great significance in reducing the incidence of postoperative pulmonary infection. Chronic obstructive pulmonary disease General anesthesia for single-lung ventilation Elderly patients Perioperative period Duration of lung ventilation Cui, Wenbin verfasserin aut Zhang, Boya verfasserin aut Shan, Shiqiang verfasserin aut Enthalten in Journal of infection and public health Amsterdam [u.a.] : Elsevier, 2008 13, Seite 281-286 Online-Ressource (DE-627)587140267 (DE-600)2467587-8 (DE-576)302178457 1876-035X nnns volume:13 pages:281-286 GBV_USEFLAG_U SYSFLAG_U GBV_ELV SSG-OLC-PHA GBV_ILN_20 GBV_ILN_22 GBV_ILN_23 GBV_ILN_24 GBV_ILN_31 GBV_ILN_39 GBV_ILN_40 GBV_ILN_60 GBV_ILN_62 GBV_ILN_63 GBV_ILN_65 GBV_ILN_69 GBV_ILN_73 GBV_ILN_74 GBV_ILN_95 GBV_ILN_100 GBV_ILN_105 GBV_ILN_110 GBV_ILN_151 GBV_ILN_161 GBV_ILN_170 GBV_ILN_206 GBV_ILN_213 GBV_ILN_224 GBV_ILN_230 GBV_ILN_285 GBV_ILN_293 GBV_ILN_602 GBV_ILN_647 GBV_ILN_2001 GBV_ILN_2003 GBV_ILN_2004 GBV_ILN_2005 GBV_ILN_2006 GBV_ILN_2007 GBV_ILN_2008 GBV_ILN_2009 GBV_ILN_2010 GBV_ILN_2011 GBV_ILN_2014 GBV_ILN_2015 GBV_ILN_2020 GBV_ILN_2021 GBV_ILN_2025 GBV_ILN_2026 GBV_ILN_2027 GBV_ILN_2034 GBV_ILN_2038 GBV_ILN_2044 GBV_ILN_2048 GBV_ILN_2049 GBV_ILN_2050 GBV_ILN_2055 GBV_ILN_2056 GBV_ILN_2059 GBV_ILN_2061 GBV_ILN_2064 GBV_ILN_2088 GBV_ILN_2106 GBV_ILN_2110 GBV_ILN_2112 GBV_ILN_2122 GBV_ILN_2129 GBV_ILN_2143 GBV_ILN_2152 GBV_ILN_2153 GBV_ILN_2190 GBV_ILN_2232 GBV_ILN_2470 GBV_ILN_2507 GBV_ILN_4012 GBV_ILN_4035 GBV_ILN_4037 GBV_ILN_4112 GBV_ILN_4125 GBV_ILN_4126 GBV_ILN_4242 GBV_ILN_4249 GBV_ILN_4251 GBV_ILN_4305 GBV_ILN_4306 GBV_ILN_4307 GBV_ILN_4313 GBV_ILN_4322 GBV_ILN_4323 GBV_ILN_4324 GBV_ILN_4325 GBV_ILN_4326 GBV_ILN_4333 GBV_ILN_4334 GBV_ILN_4338 GBV_ILN_4367 GBV_ILN_4393 GBV_ILN_4700 44.75 Infektionskrankheiten parasitäre Krankheiten Medizin AR 13 281-286 |
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10.1016/j.jiph.2019.11.021 doi (DE-627)ELV003604837 (ELSEVIER)S1876-0341(19)30366-1 DE-627 ger DE-627 rda eng 610 DE-600 44.75 bkl Ji, Xiaochen verfasserin aut Effect of lung protective ventilation on perioperative pulmonary infection in elderly patients with mild to moderate COPD under general anesthesia 2019 nicht spezifiziert zzz rdacontent Computermedien c rdamedia Online-Ressource cr rdacarrier Objective: The research aims to explore the effects of different ventilation time on postoperative pulmonary infection in elderly patients with the mild and moderate chronic pulmonary obstructive disease (COPD), so as to provide evidence for reducing postoperative pulmonary infection complications in patients with COPD.Methods: 120 elderly patients with mild and moderate COPD were selected as the research objects. First, the general information of patients with COPD before surgery and the difference between healthy population and lung forced expiratory volume in 1s (FEV1), forced vital capacity (FVC), FEV1/FVC and maximum midexpiratory flow (MMEF) functional indexes were analyzed and detected. Patients with COPD were operated on with single lung ventilation and general anesthesia. Patients with mild and moderate COPD were divided into two groups according to lung ventilation time (ventilation time 1.0–2.0h group, ventilation time >2.0h group). The inflammatory factors of IL-6, IL-21, TNF-α, and CXCL13 as well as inflammatory indicators of polycaprolactam (PCT), C-reactive protein (CRP) and white blood cell (WBC) in serum of all patients were detected after the operation. The probability of pulmonary infection after COPD was diagnosed and analyzed. Finally, the regression analysis of postoperative pulmonary infection in COPD patients was analyzed.Results: (1) The results showed that the smoking rate of mild and COPD patients was significantly higher than that of healthy people (P<0.05). (2) The lung function indexes of the mild and moderate groups were significantly lower than those of the control group (P<0.01), while the lung function indexes of the moderate group were significantly lower than those of the mild group (P<0.05). (3) All the inflammatory indicators of moderate COPD patients were significantly higher than those of mild COPD patients (P<0.05). (4) All inflammation-related indicators in patients with mild and moderate COPD with ventilation time of >2.0h were significantly higher than those in the 1.0–2.0h group (P<0.05). (5) The probability of postoperative pulmonary infection in moderate patients was significantly higher than that in mild patients (P<0.01). The probability of postoperative pulmonary infection in >2.0h group was significantly higher than that in the 1.0–2.0h group (P<0.01). (6) Multivariate Logistic regression analysis results showed that lung function, duration of lung ventilation and smoking were independent risk factors for postoperative pulmonary infection in COPD patients.Conclusion: It is important to detect pulmonary function before surgery, maintain single lung ventilation protection for no more than 2.0h during surgery, and quit smoking to improve pulmonary infection in patients with COPD after surgery. In addition, the incidence of postoperative pulmonary infection in patients with moderate COPD was higher than that in patients with mild COPD, suggesting that early treatment in patients with COPD was also of great significance in reducing the incidence of postoperative pulmonary infection. Chronic obstructive pulmonary disease General anesthesia for single-lung ventilation Elderly patients Perioperative period Duration of lung ventilation Cui, Wenbin verfasserin aut Zhang, Boya verfasserin aut Shan, Shiqiang verfasserin aut Enthalten in Journal of infection and public health Amsterdam [u.a.] : Elsevier, 2008 13, Seite 281-286 Online-Ressource (DE-627)587140267 (DE-600)2467587-8 (DE-576)302178457 1876-035X nnns volume:13 pages:281-286 GBV_USEFLAG_U SYSFLAG_U GBV_ELV SSG-OLC-PHA GBV_ILN_20 GBV_ILN_22 GBV_ILN_23 GBV_ILN_24 GBV_ILN_31 GBV_ILN_39 GBV_ILN_40 GBV_ILN_60 GBV_ILN_62 GBV_ILN_63 GBV_ILN_65 GBV_ILN_69 GBV_ILN_73 GBV_ILN_74 GBV_ILN_95 GBV_ILN_100 GBV_ILN_105 GBV_ILN_110 GBV_ILN_151 GBV_ILN_161 GBV_ILN_170 GBV_ILN_206 GBV_ILN_213 GBV_ILN_224 GBV_ILN_230 GBV_ILN_285 GBV_ILN_293 GBV_ILN_602 GBV_ILN_647 GBV_ILN_2001 GBV_ILN_2003 GBV_ILN_2004 GBV_ILN_2005 GBV_ILN_2006 GBV_ILN_2007 GBV_ILN_2008 GBV_ILN_2009 GBV_ILN_2010 GBV_ILN_2011 GBV_ILN_2014 GBV_ILN_2015 GBV_ILN_2020 GBV_ILN_2021 GBV_ILN_2025 GBV_ILN_2026 GBV_ILN_2027 GBV_ILN_2034 GBV_ILN_2038 GBV_ILN_2044 GBV_ILN_2048 GBV_ILN_2049 GBV_ILN_2050 GBV_ILN_2055 GBV_ILN_2056 GBV_ILN_2059 GBV_ILN_2061 GBV_ILN_2064 GBV_ILN_2088 GBV_ILN_2106 GBV_ILN_2110 GBV_ILN_2112 GBV_ILN_2122 GBV_ILN_2129 GBV_ILN_2143 GBV_ILN_2152 GBV_ILN_2153 GBV_ILN_2190 GBV_ILN_2232 GBV_ILN_2470 GBV_ILN_2507 GBV_ILN_4012 GBV_ILN_4035 GBV_ILN_4037 GBV_ILN_4112 GBV_ILN_4125 GBV_ILN_4126 GBV_ILN_4242 GBV_ILN_4249 GBV_ILN_4251 GBV_ILN_4305 GBV_ILN_4306 GBV_ILN_4307 GBV_ILN_4313 GBV_ILN_4322 GBV_ILN_4323 GBV_ILN_4324 GBV_ILN_4325 GBV_ILN_4326 GBV_ILN_4333 GBV_ILN_4334 GBV_ILN_4338 GBV_ILN_4367 GBV_ILN_4393 GBV_ILN_4700 44.75 Infektionskrankheiten parasitäre Krankheiten Medizin AR 13 281-286 |
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10.1016/j.jiph.2019.11.021 doi (DE-627)ELV003604837 (ELSEVIER)S1876-0341(19)30366-1 DE-627 ger DE-627 rda eng 610 DE-600 44.75 bkl Ji, Xiaochen verfasserin aut Effect of lung protective ventilation on perioperative pulmonary infection in elderly patients with mild to moderate COPD under general anesthesia 2019 nicht spezifiziert zzz rdacontent Computermedien c rdamedia Online-Ressource cr rdacarrier Objective: The research aims to explore the effects of different ventilation time on postoperative pulmonary infection in elderly patients with the mild and moderate chronic pulmonary obstructive disease (COPD), so as to provide evidence for reducing postoperative pulmonary infection complications in patients with COPD.Methods: 120 elderly patients with mild and moderate COPD were selected as the research objects. First, the general information of patients with COPD before surgery and the difference between healthy population and lung forced expiratory volume in 1s (FEV1), forced vital capacity (FVC), FEV1/FVC and maximum midexpiratory flow (MMEF) functional indexes were analyzed and detected. Patients with COPD were operated on with single lung ventilation and general anesthesia. Patients with mild and moderate COPD were divided into two groups according to lung ventilation time (ventilation time 1.0–2.0h group, ventilation time >2.0h group). The inflammatory factors of IL-6, IL-21, TNF-α, and CXCL13 as well as inflammatory indicators of polycaprolactam (PCT), C-reactive protein (CRP) and white blood cell (WBC) in serum of all patients were detected after the operation. The probability of pulmonary infection after COPD was diagnosed and analyzed. Finally, the regression analysis of postoperative pulmonary infection in COPD patients was analyzed.Results: (1) The results showed that the smoking rate of mild and COPD patients was significantly higher than that of healthy people (P<0.05). (2) The lung function indexes of the mild and moderate groups were significantly lower than those of the control group (P<0.01), while the lung function indexes of the moderate group were significantly lower than those of the mild group (P<0.05). (3) All the inflammatory indicators of moderate COPD patients were significantly higher than those of mild COPD patients (P<0.05). (4) All inflammation-related indicators in patients with mild and moderate COPD with ventilation time of >2.0h were significantly higher than those in the 1.0–2.0h group (P<0.05). (5) The probability of postoperative pulmonary infection in moderate patients was significantly higher than that in mild patients (P<0.01). The probability of postoperative pulmonary infection in >2.0h group was significantly higher than that in the 1.0–2.0h group (P<0.01). (6) Multivariate Logistic regression analysis results showed that lung function, duration of lung ventilation and smoking were independent risk factors for postoperative pulmonary infection in COPD patients.Conclusion: It is important to detect pulmonary function before surgery, maintain single lung ventilation protection for no more than 2.0h during surgery, and quit smoking to improve pulmonary infection in patients with COPD after surgery. In addition, the incidence of postoperative pulmonary infection in patients with moderate COPD was higher than that in patients with mild COPD, suggesting that early treatment in patients with COPD was also of great significance in reducing the incidence of postoperative pulmonary infection. Chronic obstructive pulmonary disease General anesthesia for single-lung ventilation Elderly patients Perioperative period Duration of lung ventilation Cui, Wenbin verfasserin aut Zhang, Boya verfasserin aut Shan, Shiqiang verfasserin aut Enthalten in Journal of infection and public health Amsterdam [u.a.] : Elsevier, 2008 13, Seite 281-286 Online-Ressource (DE-627)587140267 (DE-600)2467587-8 (DE-576)302178457 1876-035X nnns volume:13 pages:281-286 GBV_USEFLAG_U SYSFLAG_U GBV_ELV SSG-OLC-PHA GBV_ILN_20 GBV_ILN_22 GBV_ILN_23 GBV_ILN_24 GBV_ILN_31 GBV_ILN_39 GBV_ILN_40 GBV_ILN_60 GBV_ILN_62 GBV_ILN_63 GBV_ILN_65 GBV_ILN_69 GBV_ILN_73 GBV_ILN_74 GBV_ILN_95 GBV_ILN_100 GBV_ILN_105 GBV_ILN_110 GBV_ILN_151 GBV_ILN_161 GBV_ILN_170 GBV_ILN_206 GBV_ILN_213 GBV_ILN_224 GBV_ILN_230 GBV_ILN_285 GBV_ILN_293 GBV_ILN_602 GBV_ILN_647 GBV_ILN_2001 GBV_ILN_2003 GBV_ILN_2004 GBV_ILN_2005 GBV_ILN_2006 GBV_ILN_2007 GBV_ILN_2008 GBV_ILN_2009 GBV_ILN_2010 GBV_ILN_2011 GBV_ILN_2014 GBV_ILN_2015 GBV_ILN_2020 GBV_ILN_2021 GBV_ILN_2025 GBV_ILN_2026 GBV_ILN_2027 GBV_ILN_2034 GBV_ILN_2038 GBV_ILN_2044 GBV_ILN_2048 GBV_ILN_2049 GBV_ILN_2050 GBV_ILN_2055 GBV_ILN_2056 GBV_ILN_2059 GBV_ILN_2061 GBV_ILN_2064 GBV_ILN_2088 GBV_ILN_2106 GBV_ILN_2110 GBV_ILN_2112 GBV_ILN_2122 GBV_ILN_2129 GBV_ILN_2143 GBV_ILN_2152 GBV_ILN_2153 GBV_ILN_2190 GBV_ILN_2232 GBV_ILN_2470 GBV_ILN_2507 GBV_ILN_4012 GBV_ILN_4035 GBV_ILN_4037 GBV_ILN_4112 GBV_ILN_4125 GBV_ILN_4126 GBV_ILN_4242 GBV_ILN_4249 GBV_ILN_4251 GBV_ILN_4305 GBV_ILN_4306 GBV_ILN_4307 GBV_ILN_4313 GBV_ILN_4322 GBV_ILN_4323 GBV_ILN_4324 GBV_ILN_4325 GBV_ILN_4326 GBV_ILN_4333 GBV_ILN_4334 GBV_ILN_4338 GBV_ILN_4367 GBV_ILN_4393 GBV_ILN_4700 44.75 Infektionskrankheiten parasitäre Krankheiten Medizin AR 13 281-286 |
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First, the general information of patients with COPD before surgery and the difference between healthy population and lung forced expiratory volume in 1s (FEV1), forced vital capacity (FVC), FEV1/FVC and maximum midexpiratory flow (MMEF) functional indexes were analyzed and detected. Patients with COPD were operated on with single lung ventilation and general anesthesia. Patients with mild and moderate COPD were divided into two groups according to lung ventilation time (ventilation time 1.0–2.0h group, ventilation time >2.0h group). The inflammatory factors of IL-6, IL-21, TNF-α, and CXCL13 as well as inflammatory indicators of polycaprolactam (PCT), C-reactive protein (CRP) and white blood cell (WBC) in serum of all patients were detected after the operation. The probability of pulmonary infection after COPD was diagnosed and analyzed. Finally, the regression analysis of postoperative pulmonary infection in COPD patients was analyzed.Results: (1) The results showed that the smoking rate of mild and COPD patients was significantly higher than that of healthy people (P<0.05). (2) The lung function indexes of the mild and moderate groups were significantly lower than those of the control group (P<0.01), while the lung function indexes of the moderate group were significantly lower than those of the mild group (P<0.05). (3) All the inflammatory indicators of moderate COPD patients were significantly higher than those of mild COPD patients (P<0.05). (4) All inflammation-related indicators in patients with mild and moderate COPD with ventilation time of >2.0h were significantly higher than those in the 1.0–2.0h group (P<0.05). (5) The probability of postoperative pulmonary infection in moderate patients was significantly higher than that in mild patients (P<0.01). 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Ji, Xiaochen |
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Ji, Xiaochen ddc 610 bkl 44.75 misc Chronic obstructive pulmonary disease misc General anesthesia for single-lung ventilation misc Elderly patients misc Perioperative period misc Duration of lung ventilation Effect of lung protective ventilation on perioperative pulmonary infection in elderly patients with mild to moderate COPD under general anesthesia |
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610 DE-600 44.75 bkl Effect of lung protective ventilation on perioperative pulmonary infection in elderly patients with mild to moderate COPD under general anesthesia Chronic obstructive pulmonary disease General anesthesia for single-lung ventilation Elderly patients Perioperative period Duration of lung ventilation |
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ddc 610 bkl 44.75 misc Chronic obstructive pulmonary disease misc General anesthesia for single-lung ventilation misc Elderly patients misc Perioperative period misc Duration of lung ventilation |
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ddc 610 bkl 44.75 misc Chronic obstructive pulmonary disease misc General anesthesia for single-lung ventilation misc Elderly patients misc Perioperative period misc Duration of lung ventilation |
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ddc 610 bkl 44.75 misc Chronic obstructive pulmonary disease misc General anesthesia for single-lung ventilation misc Elderly patients misc Perioperative period misc Duration of lung ventilation |
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Effect of lung protective ventilation on perioperative pulmonary infection in elderly patients with mild to moderate COPD under general anesthesia |
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Effect of lung protective ventilation on perioperative pulmonary infection in elderly patients with mild to moderate COPD under general anesthesia |
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Ji, Xiaochen Cui, Wenbin Zhang, Boya Shan, Shiqiang |
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effect of lung protective ventilation on perioperative pulmonary infection in elderly patients with mild to moderate copd under general anesthesia |
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Effect of lung protective ventilation on perioperative pulmonary infection in elderly patients with mild to moderate COPD under general anesthesia |
| abstract |
Objective: The research aims to explore the effects of different ventilation time on postoperative pulmonary infection in elderly patients with the mild and moderate chronic pulmonary obstructive disease (COPD), so as to provide evidence for reducing postoperative pulmonary infection complications in patients with COPD.Methods: 120 elderly patients with mild and moderate COPD were selected as the research objects. First, the general information of patients with COPD before surgery and the difference between healthy population and lung forced expiratory volume in 1s (FEV1), forced vital capacity (FVC), FEV1/FVC and maximum midexpiratory flow (MMEF) functional indexes were analyzed and detected. Patients with COPD were operated on with single lung ventilation and general anesthesia. Patients with mild and moderate COPD were divided into two groups according to lung ventilation time (ventilation time 1.0–2.0h group, ventilation time >2.0h group). The inflammatory factors of IL-6, IL-21, TNF-α, and CXCL13 as well as inflammatory indicators of polycaprolactam (PCT), C-reactive protein (CRP) and white blood cell (WBC) in serum of all patients were detected after the operation. The probability of pulmonary infection after COPD was diagnosed and analyzed. Finally, the regression analysis of postoperative pulmonary infection in COPD patients was analyzed.Results: (1) The results showed that the smoking rate of mild and COPD patients was significantly higher than that of healthy people (P<0.05). (2) The lung function indexes of the mild and moderate groups were significantly lower than those of the control group (P<0.01), while the lung function indexes of the moderate group were significantly lower than those of the mild group (P<0.05). (3) All the inflammatory indicators of moderate COPD patients were significantly higher than those of mild COPD patients (P<0.05). (4) All inflammation-related indicators in patients with mild and moderate COPD with ventilation time of >2.0h were significantly higher than those in the 1.0–2.0h group (P<0.05). (5) The probability of postoperative pulmonary infection in moderate patients was significantly higher than that in mild patients (P<0.01). The probability of postoperative pulmonary infection in >2.0h group was significantly higher than that in the 1.0–2.0h group (P<0.01). (6) Multivariate Logistic regression analysis results showed that lung function, duration of lung ventilation and smoking were independent risk factors for postoperative pulmonary infection in COPD patients.Conclusion: It is important to detect pulmonary function before surgery, maintain single lung ventilation protection for no more than 2.0h during surgery, and quit smoking to improve pulmonary infection in patients with COPD after surgery. In addition, the incidence of postoperative pulmonary infection in patients with moderate COPD was higher than that in patients with mild COPD, suggesting that early treatment in patients with COPD was also of great significance in reducing the incidence of postoperative pulmonary infection. |
| abstractGer |
Objective: The research aims to explore the effects of different ventilation time on postoperative pulmonary infection in elderly patients with the mild and moderate chronic pulmonary obstructive disease (COPD), so as to provide evidence for reducing postoperative pulmonary infection complications in patients with COPD.Methods: 120 elderly patients with mild and moderate COPD were selected as the research objects. First, the general information of patients with COPD before surgery and the difference between healthy population and lung forced expiratory volume in 1s (FEV1), forced vital capacity (FVC), FEV1/FVC and maximum midexpiratory flow (MMEF) functional indexes were analyzed and detected. Patients with COPD were operated on with single lung ventilation and general anesthesia. Patients with mild and moderate COPD were divided into two groups according to lung ventilation time (ventilation time 1.0–2.0h group, ventilation time >2.0h group). The inflammatory factors of IL-6, IL-21, TNF-α, and CXCL13 as well as inflammatory indicators of polycaprolactam (PCT), C-reactive protein (CRP) and white blood cell (WBC) in serum of all patients were detected after the operation. The probability of pulmonary infection after COPD was diagnosed and analyzed. Finally, the regression analysis of postoperative pulmonary infection in COPD patients was analyzed.Results: (1) The results showed that the smoking rate of mild and COPD patients was significantly higher than that of healthy people (P<0.05). (2) The lung function indexes of the mild and moderate groups were significantly lower than those of the control group (P<0.01), while the lung function indexes of the moderate group were significantly lower than those of the mild group (P<0.05). (3) All the inflammatory indicators of moderate COPD patients were significantly higher than those of mild COPD patients (P<0.05). (4) All inflammation-related indicators in patients with mild and moderate COPD with ventilation time of >2.0h were significantly higher than those in the 1.0–2.0h group (P<0.05). (5) The probability of postoperative pulmonary infection in moderate patients was significantly higher than that in mild patients (P<0.01). The probability of postoperative pulmonary infection in >2.0h group was significantly higher than that in the 1.0–2.0h group (P<0.01). (6) Multivariate Logistic regression analysis results showed that lung function, duration of lung ventilation and smoking were independent risk factors for postoperative pulmonary infection in COPD patients.Conclusion: It is important to detect pulmonary function before surgery, maintain single lung ventilation protection for no more than 2.0h during surgery, and quit smoking to improve pulmonary infection in patients with COPD after surgery. In addition, the incidence of postoperative pulmonary infection in patients with moderate COPD was higher than that in patients with mild COPD, suggesting that early treatment in patients with COPD was also of great significance in reducing the incidence of postoperative pulmonary infection. |
| abstract_unstemmed |
Objective: The research aims to explore the effects of different ventilation time on postoperative pulmonary infection in elderly patients with the mild and moderate chronic pulmonary obstructive disease (COPD), so as to provide evidence for reducing postoperative pulmonary infection complications in patients with COPD.Methods: 120 elderly patients with mild and moderate COPD were selected as the research objects. First, the general information of patients with COPD before surgery and the difference between healthy population and lung forced expiratory volume in 1s (FEV1), forced vital capacity (FVC), FEV1/FVC and maximum midexpiratory flow (MMEF) functional indexes were analyzed and detected. Patients with COPD were operated on with single lung ventilation and general anesthesia. Patients with mild and moderate COPD were divided into two groups according to lung ventilation time (ventilation time 1.0–2.0h group, ventilation time >2.0h group). The inflammatory factors of IL-6, IL-21, TNF-α, and CXCL13 as well as inflammatory indicators of polycaprolactam (PCT), C-reactive protein (CRP) and white blood cell (WBC) in serum of all patients were detected after the operation. The probability of pulmonary infection after COPD was diagnosed and analyzed. Finally, the regression analysis of postoperative pulmonary infection in COPD patients was analyzed.Results: (1) The results showed that the smoking rate of mild and COPD patients was significantly higher than that of healthy people (P<0.05). (2) The lung function indexes of the mild and moderate groups were significantly lower than those of the control group (P<0.01), while the lung function indexes of the moderate group were significantly lower than those of the mild group (P<0.05). (3) All the inflammatory indicators of moderate COPD patients were significantly higher than those of mild COPD patients (P<0.05). (4) All inflammation-related indicators in patients with mild and moderate COPD with ventilation time of >2.0h were significantly higher than those in the 1.0–2.0h group (P<0.05). (5) The probability of postoperative pulmonary infection in moderate patients was significantly higher than that in mild patients (P<0.01). The probability of postoperative pulmonary infection in >2.0h group was significantly higher than that in the 1.0–2.0h group (P<0.01). (6) Multivariate Logistic regression analysis results showed that lung function, duration of lung ventilation and smoking were independent risk factors for postoperative pulmonary infection in COPD patients.Conclusion: It is important to detect pulmonary function before surgery, maintain single lung ventilation protection for no more than 2.0h during surgery, and quit smoking to improve pulmonary infection in patients with COPD after surgery. In addition, the incidence of postoperative pulmonary infection in patients with moderate COPD was higher than that in patients with mild COPD, suggesting that early treatment in patients with COPD was also of great significance in reducing the incidence of postoperative pulmonary infection. |
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<?xml version="1.0" encoding="UTF-8"?><collection xmlns="http://www.loc.gov/MARC21/slim"><record><leader>01000caa a22002652 4500</leader><controlfield tag="001">ELV003604837</controlfield><controlfield tag="003">DE-627</controlfield><controlfield tag="005">20230524164117.0</controlfield><controlfield tag="007">cr uuu---uuuuu</controlfield><controlfield tag="008">230501s2019 xx |||||o 00| ||eng c</controlfield><datafield tag="024" ind1="7" ind2=" "><subfield code="a">10.1016/j.jiph.2019.11.021</subfield><subfield code="2">doi</subfield></datafield><datafield tag="035" ind1=" " ind2=" "><subfield code="a">(DE-627)ELV003604837</subfield></datafield><datafield tag="035" ind1=" " ind2=" "><subfield code="a">(ELSEVIER)S1876-0341(19)30366-1</subfield></datafield><datafield tag="040" ind1=" " ind2=" "><subfield code="a">DE-627</subfield><subfield code="b">ger</subfield><subfield code="c">DE-627</subfield><subfield code="e">rda</subfield></datafield><datafield tag="041" ind1=" " ind2=" "><subfield code="a">eng</subfield></datafield><datafield tag="082" ind1="0" ind2="4"><subfield code="a">610</subfield><subfield code="q">DE-600</subfield></datafield><datafield tag="084" ind1=" " ind2=" "><subfield code="a">44.75</subfield><subfield code="2">bkl</subfield></datafield><datafield tag="100" ind1="1" ind2=" "><subfield code="a">Ji, Xiaochen</subfield><subfield code="e">verfasserin</subfield><subfield code="4">aut</subfield></datafield><datafield tag="245" ind1="1" ind2="0"><subfield code="a">Effect of lung protective ventilation on perioperative pulmonary infection in elderly patients with mild to moderate COPD under general anesthesia</subfield></datafield><datafield tag="264" ind1=" " ind2="1"><subfield code="c">2019</subfield></datafield><datafield tag="336" ind1=" " ind2=" "><subfield code="a">nicht spezifiziert</subfield><subfield code="b">zzz</subfield><subfield code="2">rdacontent</subfield></datafield><datafield tag="337" ind1=" " ind2=" "><subfield code="a">Computermedien</subfield><subfield code="b">c</subfield><subfield code="2">rdamedia</subfield></datafield><datafield tag="338" ind1=" " ind2=" "><subfield code="a">Online-Ressource</subfield><subfield code="b">cr</subfield><subfield code="2">rdacarrier</subfield></datafield><datafield tag="520" ind1=" " ind2=" "><subfield code="a">Objective: The research aims to explore the effects of different ventilation time on postoperative pulmonary infection in elderly patients with the mild and moderate chronic pulmonary obstructive disease (COPD), so as to provide evidence for reducing postoperative pulmonary infection complications in patients with COPD.Methods: 120 elderly patients with mild and moderate COPD were selected as the research objects. First, the general information of patients with COPD before surgery and the difference between healthy population and lung forced expiratory volume in 1s (FEV1), forced vital capacity (FVC), FEV1/FVC and maximum midexpiratory flow (MMEF) functional indexes were analyzed and detected. Patients with COPD were operated on with single lung ventilation and general anesthesia. Patients with mild and moderate COPD were divided into two groups according to lung ventilation time (ventilation time 1.0–2.0h group, ventilation time >2.0h group). The inflammatory factors of IL-6, IL-21, TNF-α, and CXCL13 as well as inflammatory indicators of polycaprolactam (PCT), C-reactive protein (CRP) and white blood cell (WBC) in serum of all patients were detected after the operation. The probability of pulmonary infection after COPD was diagnosed and analyzed. Finally, the regression analysis of postoperative pulmonary infection in COPD patients was analyzed.Results: (1) The results showed that the smoking rate of mild and COPD patients was significantly higher than that of healthy people (P<0.05). (2) The lung function indexes of the mild and moderate groups were significantly lower than those of the control group (P<0.01), while the lung function indexes of the moderate group were significantly lower than those of the mild group (P<0.05). (3) All the inflammatory indicators of moderate COPD patients were significantly higher than those of mild COPD patients (P<0.05). (4) All inflammation-related indicators in patients with mild and moderate COPD with ventilation time of >2.0h were significantly higher than those in the 1.0–2.0h group (P<0.05). (5) The probability of postoperative pulmonary infection in moderate patients was significantly higher than that in mild patients (P<0.01). The probability of postoperative pulmonary infection in >2.0h group was significantly higher than that in the 1.0–2.0h group (P<0.01). (6) Multivariate Logistic regression analysis results showed that lung function, duration of lung ventilation and smoking were independent risk factors for postoperative pulmonary infection in COPD patients.Conclusion: It is important to detect pulmonary function before surgery, maintain single lung ventilation protection for no more than 2.0h during surgery, and quit smoking to improve pulmonary infection in patients with COPD after surgery. In addition, the incidence of postoperative pulmonary infection in patients with moderate COPD was higher than that in patients with mild COPD, suggesting that early treatment in patients with COPD was also of great significance in reducing the incidence of postoperative pulmonary infection.</subfield></datafield><datafield tag="650" ind1=" " ind2="4"><subfield code="a">Chronic obstructive pulmonary disease</subfield></datafield><datafield tag="650" ind1=" " ind2="4"><subfield code="a">General anesthesia for single-lung ventilation</subfield></datafield><datafield tag="650" ind1=" " ind2="4"><subfield code="a">Elderly patients</subfield></datafield><datafield tag="650" ind1=" " ind2="4"><subfield code="a">Perioperative period</subfield></datafield><datafield tag="650" ind1=" " ind2="4"><subfield code="a">Duration of lung ventilation</subfield></datafield><datafield tag="700" ind1="1" ind2=" "><subfield code="a">Cui, Wenbin</subfield><subfield code="e">verfasserin</subfield><subfield code="4">aut</subfield></datafield><datafield tag="700" ind1="1" ind2=" "><subfield code="a">Zhang, Boya</subfield><subfield code="e">verfasserin</subfield><subfield code="4">aut</subfield></datafield><datafield tag="700" ind1="1" ind2=" "><subfield code="a">Shan, Shiqiang</subfield><subfield code="e">verfasserin</subfield><subfield code="4">aut</subfield></datafield><datafield tag="773" ind1="0" ind2="8"><subfield code="i">Enthalten in</subfield><subfield code="t">Journal of infection and public health</subfield><subfield code="d">Amsterdam [u.a.] : Elsevier, 2008</subfield><subfield code="g">13, Seite 281-286</subfield><subfield code="h">Online-Ressource</subfield><subfield code="w">(DE-627)587140267</subfield><subfield code="w">(DE-600)2467587-8</subfield><subfield code="w">(DE-576)302178457</subfield><subfield code="x">1876-035X</subfield><subfield code="7">nnns</subfield></datafield><datafield tag="773" ind1="1" ind2="8"><subfield code="g">volume:13</subfield><subfield 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