Reprogramming extracellular vesicles with engineered proteins

Extracellular vesicles (EVs) have been emerging as a new class of cell-free therapy for the treatment of a variety of diseases, including cancer, tissue injuries, and inflammatory diseases. Reprograming native EVs by genetic engineering and other approaches offers an attractive prospect of extending...
Ausführliche Beschreibung

Gespeichert in:

Autor*in:	Shi, Xiaojing [verfasserIn] Cheng, Qinqin [verfasserIn] Zhang, Yong [verfasserIn]

Format:	E-Artikel
Sprache:	Englisch

Erschienen:	2019

Schlagwörter:	Extracellular vesicles Protein engineering Fusion protein Drug delivery Cell-free therapy

Übergeordnetes Werk:	Enthalten in: Methods - Orlando, Fla. : Academic Press, 1990, 177, Seite 95-102
Übergeordnetes Werk:	volume:177 ; pages:95-102

DOI / URN:	10.1016/j.ymeth.2019.09.017

Katalog-ID:	ELV00402401X

Internformat


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650		4	\|a Extracellular vesicles
650		4	\|a Protein engineering
650		4	\|a Fusion protein
650		4	\|a Drug delivery
650		4	\|a Cell-free therapy
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700	1		\|a Zhang, Yong \|e verfasserin \|4 aut
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912			\|a GBV_ILN_63
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912			\|a GBV_ILN_70
912			\|a GBV_ILN_73
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912			\|a GBV_ILN_2065
912			\|a GBV_ILN_2068
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912			\|a GBV_ILN_2507
912			\|a GBV_ILN_2522
912			\|a GBV_ILN_4035
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912			\|a GBV_ILN_4251
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912			\|a GBV_ILN_4335
912			\|a GBV_ILN_4338
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matchkey_str	article:10959130:2019----::ergamnetaellreilsihni
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publishDate	2019
allfields	10.1016/j.ymeth.2019.09.017 doi (DE-627)ELV00402401X (ELSEVIER)S1046-2023(19)30217-8 DE-627 ger DE-627 rda eng 540 DE-600 BIODIV DE-30 fid 35.74 bkl Shi, Xiaojing verfasserin aut Reprogramming extracellular vesicles with engineered proteins 2019 nicht spezifiziert zzz rdacontent Computermedien c rdamedia Online-Ressource cr rdacarrier Extracellular vesicles (EVs) have been emerging as a new class of cell-free therapy for the treatment of a variety of diseases, including cancer, tissue injuries, and inflammatory diseases. Reprograming native EVs by genetic engineering and other approaches offers an attractive prospect of extending therapeutic capabilities of EVs beyond their natural functions and properties. In this review article, we survey the state-of-the-art methods of EVs engineering and summarize major therapeutic applications of the reprogrammed EVs. Extracellular vesicles Protein engineering Fusion protein Drug delivery Cell-free therapy Cheng, Qinqin verfasserin aut Zhang, Yong verfasserin aut Enthalten in Methods Orlando, Fla. : Academic Press, 1990 177, Seite 95-102 Online-Ressource (DE-627)26784008X (DE-600)1471152-7 (DE-576)104193972 1095-9130 nnns volume:177 pages:95-102 GBV_USEFLAG_U SYSFLAG_U GBV_ELV FID-BIODIV SSG-OLC-PHA GBV_ILN_20 GBV_ILN_22 GBV_ILN_23 GBV_ILN_24 GBV_ILN_31 GBV_ILN_32 GBV_ILN_40 GBV_ILN_60 GBV_ILN_62 GBV_ILN_63 GBV_ILN_65 GBV_ILN_69 GBV_ILN_70 GBV_ILN_73 GBV_ILN_74 GBV_ILN_90 GBV_ILN_95 GBV_ILN_100 GBV_ILN_101 GBV_ILN_105 GBV_ILN_110 GBV_ILN_151 GBV_ILN_224 GBV_ILN_370 GBV_ILN_602 GBV_ILN_702 GBV_ILN_2003 GBV_ILN_2004 GBV_ILN_2005 GBV_ILN_2011 GBV_ILN_2014 GBV_ILN_2015 GBV_ILN_2020 GBV_ILN_2021 GBV_ILN_2025 GBV_ILN_2027 GBV_ILN_2034 GBV_ILN_2038 GBV_ILN_2044 GBV_ILN_2048 GBV_ILN_2049 GBV_ILN_2050 GBV_ILN_2056 GBV_ILN_2059 GBV_ILN_2061 GBV_ILN_2064 GBV_ILN_2065 GBV_ILN_2068 GBV_ILN_2111 GBV_ILN_2112 GBV_ILN_2113 GBV_ILN_2118 GBV_ILN_2122 GBV_ILN_2129 GBV_ILN_2143 GBV_ILN_2147 GBV_ILN_2148 GBV_ILN_2152 GBV_ILN_2153 GBV_ILN_2190 GBV_ILN_2336 GBV_ILN_2507 GBV_ILN_2522 GBV_ILN_4035 GBV_ILN_4037 GBV_ILN_4112 GBV_ILN_4125 GBV_ILN_4126 GBV_ILN_4242 GBV_ILN_4251 GBV_ILN_4305 GBV_ILN_4313 GBV_ILN_4323 GBV_ILN_4324 GBV_ILN_4326 GBV_ILN_4333 GBV_ILN_4334 GBV_ILN_4335 GBV_ILN_4338 GBV_ILN_4393 35.74 Enzyme Hormone Vitamine Biochemie AR 177 95-102
spelling	10.1016/j.ymeth.2019.09.017 doi (DE-627)ELV00402401X (ELSEVIER)S1046-2023(19)30217-8 DE-627 ger DE-627 rda eng 540 DE-600 BIODIV DE-30 fid 35.74 bkl Shi, Xiaojing verfasserin aut Reprogramming extracellular vesicles with engineered proteins 2019 nicht spezifiziert zzz rdacontent Computermedien c rdamedia Online-Ressource cr rdacarrier Extracellular vesicles (EVs) have been emerging as a new class of cell-free therapy for the treatment of a variety of diseases, including cancer, tissue injuries, and inflammatory diseases. Reprograming native EVs by genetic engineering and other approaches offers an attractive prospect of extending therapeutic capabilities of EVs beyond their natural functions and properties. In this review article, we survey the state-of-the-art methods of EVs engineering and summarize major therapeutic applications of the reprogrammed EVs. Extracellular vesicles Protein engineering Fusion protein Drug delivery Cell-free therapy Cheng, Qinqin verfasserin aut Zhang, Yong verfasserin aut Enthalten in Methods Orlando, Fla. : Academic Press, 1990 177, Seite 95-102 Online-Ressource (DE-627)26784008X (DE-600)1471152-7 (DE-576)104193972 1095-9130 nnns volume:177 pages:95-102 GBV_USEFLAG_U SYSFLAG_U GBV_ELV FID-BIODIV SSG-OLC-PHA GBV_ILN_20 GBV_ILN_22 GBV_ILN_23 GBV_ILN_24 GBV_ILN_31 GBV_ILN_32 GBV_ILN_40 GBV_ILN_60 GBV_ILN_62 GBV_ILN_63 GBV_ILN_65 GBV_ILN_69 GBV_ILN_70 GBV_ILN_73 GBV_ILN_74 GBV_ILN_90 GBV_ILN_95 GBV_ILN_100 GBV_ILN_101 GBV_ILN_105 GBV_ILN_110 GBV_ILN_151 GBV_ILN_224 GBV_ILN_370 GBV_ILN_602 GBV_ILN_702 GBV_ILN_2003 GBV_ILN_2004 GBV_ILN_2005 GBV_ILN_2011 GBV_ILN_2014 GBV_ILN_2015 GBV_ILN_2020 GBV_ILN_2021 GBV_ILN_2025 GBV_ILN_2027 GBV_ILN_2034 GBV_ILN_2038 GBV_ILN_2044 GBV_ILN_2048 GBV_ILN_2049 GBV_ILN_2050 GBV_ILN_2056 GBV_ILN_2059 GBV_ILN_2061 GBV_ILN_2064 GBV_ILN_2065 GBV_ILN_2068 GBV_ILN_2111 GBV_ILN_2112 GBV_ILN_2113 GBV_ILN_2118 GBV_ILN_2122 GBV_ILN_2129 GBV_ILN_2143 GBV_ILN_2147 GBV_ILN_2148 GBV_ILN_2152 GBV_ILN_2153 GBV_ILN_2190 GBV_ILN_2336 GBV_ILN_2507 GBV_ILN_2522 GBV_ILN_4035 GBV_ILN_4037 GBV_ILN_4112 GBV_ILN_4125 GBV_ILN_4126 GBV_ILN_4242 GBV_ILN_4251 GBV_ILN_4305 GBV_ILN_4313 GBV_ILN_4323 GBV_ILN_4324 GBV_ILN_4326 GBV_ILN_4333 GBV_ILN_4334 GBV_ILN_4335 GBV_ILN_4338 GBV_ILN_4393 35.74 Enzyme Hormone Vitamine Biochemie AR 177 95-102
allfields_unstemmed	10.1016/j.ymeth.2019.09.017 doi (DE-627)ELV00402401X (ELSEVIER)S1046-2023(19)30217-8 DE-627 ger DE-627 rda eng 540 DE-600 BIODIV DE-30 fid 35.74 bkl Shi, Xiaojing verfasserin aut Reprogramming extracellular vesicles with engineered proteins 2019 nicht spezifiziert zzz rdacontent Computermedien c rdamedia Online-Ressource cr rdacarrier Extracellular vesicles (EVs) have been emerging as a new class of cell-free therapy for the treatment of a variety of diseases, including cancer, tissue injuries, and inflammatory diseases. Reprograming native EVs by genetic engineering and other approaches offers an attractive prospect of extending therapeutic capabilities of EVs beyond their natural functions and properties. In this review article, we survey the state-of-the-art methods of EVs engineering and summarize major therapeutic applications of the reprogrammed EVs. Extracellular vesicles Protein engineering Fusion protein Drug delivery Cell-free therapy Cheng, Qinqin verfasserin aut Zhang, Yong verfasserin aut Enthalten in Methods Orlando, Fla. : Academic Press, 1990 177, Seite 95-102 Online-Ressource (DE-627)26784008X (DE-600)1471152-7 (DE-576)104193972 1095-9130 nnns volume:177 pages:95-102 GBV_USEFLAG_U SYSFLAG_U GBV_ELV FID-BIODIV SSG-OLC-PHA GBV_ILN_20 GBV_ILN_22 GBV_ILN_23 GBV_ILN_24 GBV_ILN_31 GBV_ILN_32 GBV_ILN_40 GBV_ILN_60 GBV_ILN_62 GBV_ILN_63 GBV_ILN_65 GBV_ILN_69 GBV_ILN_70 GBV_ILN_73 GBV_ILN_74 GBV_ILN_90 GBV_ILN_95 GBV_ILN_100 GBV_ILN_101 GBV_ILN_105 GBV_ILN_110 GBV_ILN_151 GBV_ILN_224 GBV_ILN_370 GBV_ILN_602 GBV_ILN_702 GBV_ILN_2003 GBV_ILN_2004 GBV_ILN_2005 GBV_ILN_2011 GBV_ILN_2014 GBV_ILN_2015 GBV_ILN_2020 GBV_ILN_2021 GBV_ILN_2025 GBV_ILN_2027 GBV_ILN_2034 GBV_ILN_2038 GBV_ILN_2044 GBV_ILN_2048 GBV_ILN_2049 GBV_ILN_2050 GBV_ILN_2056 GBV_ILN_2059 GBV_ILN_2061 GBV_ILN_2064 GBV_ILN_2065 GBV_ILN_2068 GBV_ILN_2111 GBV_ILN_2112 GBV_ILN_2113 GBV_ILN_2118 GBV_ILN_2122 GBV_ILN_2129 GBV_ILN_2143 GBV_ILN_2147 GBV_ILN_2148 GBV_ILN_2152 GBV_ILN_2153 GBV_ILN_2190 GBV_ILN_2336 GBV_ILN_2507 GBV_ILN_2522 GBV_ILN_4035 GBV_ILN_4037 GBV_ILN_4112 GBV_ILN_4125 GBV_ILN_4126 GBV_ILN_4242 GBV_ILN_4251 GBV_ILN_4305 GBV_ILN_4313 GBV_ILN_4323 GBV_ILN_4324 GBV_ILN_4326 GBV_ILN_4333 GBV_ILN_4334 GBV_ILN_4335 GBV_ILN_4338 GBV_ILN_4393 35.74 Enzyme Hormone Vitamine Biochemie AR 177 95-102
allfieldsGer	10.1016/j.ymeth.2019.09.017 doi (DE-627)ELV00402401X (ELSEVIER)S1046-2023(19)30217-8 DE-627 ger DE-627 rda eng 540 DE-600 BIODIV DE-30 fid 35.74 bkl Shi, Xiaojing verfasserin aut Reprogramming extracellular vesicles with engineered proteins 2019 nicht spezifiziert zzz rdacontent Computermedien c rdamedia Online-Ressource cr rdacarrier Extracellular vesicles (EVs) have been emerging as a new class of cell-free therapy for the treatment of a variety of diseases, including cancer, tissue injuries, and inflammatory diseases. Reprograming native EVs by genetic engineering and other approaches offers an attractive prospect of extending therapeutic capabilities of EVs beyond their natural functions and properties. In this review article, we survey the state-of-the-art methods of EVs engineering and summarize major therapeutic applications of the reprogrammed EVs. Extracellular vesicles Protein engineering Fusion protein Drug delivery Cell-free therapy Cheng, Qinqin verfasserin aut Zhang, Yong verfasserin aut Enthalten in Methods Orlando, Fla. : Academic Press, 1990 177, Seite 95-102 Online-Ressource (DE-627)26784008X (DE-600)1471152-7 (DE-576)104193972 1095-9130 nnns volume:177 pages:95-102 GBV_USEFLAG_U SYSFLAG_U GBV_ELV FID-BIODIV SSG-OLC-PHA GBV_ILN_20 GBV_ILN_22 GBV_ILN_23 GBV_ILN_24 GBV_ILN_31 GBV_ILN_32 GBV_ILN_40 GBV_ILN_60 GBV_ILN_62 GBV_ILN_63 GBV_ILN_65 GBV_ILN_69 GBV_ILN_70 GBV_ILN_73 GBV_ILN_74 GBV_ILN_90 GBV_ILN_95 GBV_ILN_100 GBV_ILN_101 GBV_ILN_105 GBV_ILN_110 GBV_ILN_151 GBV_ILN_224 GBV_ILN_370 GBV_ILN_602 GBV_ILN_702 GBV_ILN_2003 GBV_ILN_2004 GBV_ILN_2005 GBV_ILN_2011 GBV_ILN_2014 GBV_ILN_2015 GBV_ILN_2020 GBV_ILN_2021 GBV_ILN_2025 GBV_ILN_2027 GBV_ILN_2034 GBV_ILN_2038 GBV_ILN_2044 GBV_ILN_2048 GBV_ILN_2049 GBV_ILN_2050 GBV_ILN_2056 GBV_ILN_2059 GBV_ILN_2061 GBV_ILN_2064 GBV_ILN_2065 GBV_ILN_2068 GBV_ILN_2111 GBV_ILN_2112 GBV_ILN_2113 GBV_ILN_2118 GBV_ILN_2122 GBV_ILN_2129 GBV_ILN_2143 GBV_ILN_2147 GBV_ILN_2148 GBV_ILN_2152 GBV_ILN_2153 GBV_ILN_2190 GBV_ILN_2336 GBV_ILN_2507 GBV_ILN_2522 GBV_ILN_4035 GBV_ILN_4037 GBV_ILN_4112 GBV_ILN_4125 GBV_ILN_4126 GBV_ILN_4242 GBV_ILN_4251 GBV_ILN_4305 GBV_ILN_4313 GBV_ILN_4323 GBV_ILN_4324 GBV_ILN_4326 GBV_ILN_4333 GBV_ILN_4334 GBV_ILN_4335 GBV_ILN_4338 GBV_ILN_4393 35.74 Enzyme Hormone Vitamine Biochemie AR 177 95-102
allfieldsSound	10.1016/j.ymeth.2019.09.017 doi (DE-627)ELV00402401X (ELSEVIER)S1046-2023(19)30217-8 DE-627 ger DE-627 rda eng 540 DE-600 BIODIV DE-30 fid 35.74 bkl Shi, Xiaojing verfasserin aut Reprogramming extracellular vesicles with engineered proteins 2019 nicht spezifiziert zzz rdacontent Computermedien c rdamedia Online-Ressource cr rdacarrier Extracellular vesicles (EVs) have been emerging as a new class of cell-free therapy for the treatment of a variety of diseases, including cancer, tissue injuries, and inflammatory diseases. Reprograming native EVs by genetic engineering and other approaches offers an attractive prospect of extending therapeutic capabilities of EVs beyond their natural functions and properties. In this review article, we survey the state-of-the-art methods of EVs engineering and summarize major therapeutic applications of the reprogrammed EVs. Extracellular vesicles Protein engineering Fusion protein Drug delivery Cell-free therapy Cheng, Qinqin verfasserin aut Zhang, Yong verfasserin aut Enthalten in Methods Orlando, Fla. : Academic Press, 1990 177, Seite 95-102 Online-Ressource (DE-627)26784008X (DE-600)1471152-7 (DE-576)104193972 1095-9130 nnns volume:177 pages:95-102 GBV_USEFLAG_U SYSFLAG_U GBV_ELV FID-BIODIV SSG-OLC-PHA GBV_ILN_20 GBV_ILN_22 GBV_ILN_23 GBV_ILN_24 GBV_ILN_31 GBV_ILN_32 GBV_ILN_40 GBV_ILN_60 GBV_ILN_62 GBV_ILN_63 GBV_ILN_65 GBV_ILN_69 GBV_ILN_70 GBV_ILN_73 GBV_ILN_74 GBV_ILN_90 GBV_ILN_95 GBV_ILN_100 GBV_ILN_101 GBV_ILN_105 GBV_ILN_110 GBV_ILN_151 GBV_ILN_224 GBV_ILN_370 GBV_ILN_602 GBV_ILN_702 GBV_ILN_2003 GBV_ILN_2004 GBV_ILN_2005 GBV_ILN_2011 GBV_ILN_2014 GBV_ILN_2015 GBV_ILN_2020 GBV_ILN_2021 GBV_ILN_2025 GBV_ILN_2027 GBV_ILN_2034 GBV_ILN_2038 GBV_ILN_2044 GBV_ILN_2048 GBV_ILN_2049 GBV_ILN_2050 GBV_ILN_2056 GBV_ILN_2059 GBV_ILN_2061 GBV_ILN_2064 GBV_ILN_2065 GBV_ILN_2068 GBV_ILN_2111 GBV_ILN_2112 GBV_ILN_2113 GBV_ILN_2118 GBV_ILN_2122 GBV_ILN_2129 GBV_ILN_2143 GBV_ILN_2147 GBV_ILN_2148 GBV_ILN_2152 GBV_ILN_2153 GBV_ILN_2190 GBV_ILN_2336 GBV_ILN_2507 GBV_ILN_2522 GBV_ILN_4035 GBV_ILN_4037 GBV_ILN_4112 GBV_ILN_4125 GBV_ILN_4126 GBV_ILN_4242 GBV_ILN_4251 GBV_ILN_4305 GBV_ILN_4313 GBV_ILN_4323 GBV_ILN_4324 GBV_ILN_4326 GBV_ILN_4333 GBV_ILN_4334 GBV_ILN_4335 GBV_ILN_4338 GBV_ILN_4393 35.74 Enzyme Hormone Vitamine Biochemie AR 177 95-102
language	English
source	Enthalten in Methods 177, Seite 95-102 volume:177 pages:95-102
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topic_facet	Extracellular vesicles Protein engineering Fusion protein Drug delivery Cell-free therapy
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container_title	Methods
authorswithroles_txt_mv	Shi, Xiaojing @@aut@@ Cheng, Qinqin @@aut@@ Zhang, Yong @@aut@@
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author	Shi, Xiaojing
spellingShingle	Shi, Xiaojing ddc 540 fid BIODIV bkl 35.74 misc Extracellular vesicles misc Protein engineering misc Fusion protein misc Drug delivery misc Cell-free therapy Reprogramming extracellular vesicles with engineered proteins
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topic_title	540 DE-600 BIODIV DE-30 fid 35.74 bkl Reprogramming extracellular vesicles with engineered proteins Extracellular vesicles Protein engineering Fusion protein Drug delivery Cell-free therapy
topic	ddc 540 fid BIODIV bkl 35.74 misc Extracellular vesicles misc Protein engineering misc Fusion protein misc Drug delivery misc Cell-free therapy
topic_unstemmed	ddc 540 fid BIODIV bkl 35.74 misc Extracellular vesicles misc Protein engineering misc Fusion protein misc Drug delivery misc Cell-free therapy
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title	Reprogramming extracellular vesicles with engineered proteins
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title_full	Reprogramming extracellular vesicles with engineered proteins
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title_sort	reprogramming extracellular vesicles with engineered proteins
title_auth	Reprogramming extracellular vesicles with engineered proteins
abstract	Extracellular vesicles (EVs) have been emerging as a new class of cell-free therapy for the treatment of a variety of diseases, including cancer, tissue injuries, and inflammatory diseases. Reprograming native EVs by genetic engineering and other approaches offers an attractive prospect of extending therapeutic capabilities of EVs beyond their natural functions and properties. In this review article, we survey the state-of-the-art methods of EVs engineering and summarize major therapeutic applications of the reprogrammed EVs.
abstractGer	Extracellular vesicles (EVs) have been emerging as a new class of cell-free therapy for the treatment of a variety of diseases, including cancer, tissue injuries, and inflammatory diseases. Reprograming native EVs by genetic engineering and other approaches offers an attractive prospect of extending therapeutic capabilities of EVs beyond their natural functions and properties. In this review article, we survey the state-of-the-art methods of EVs engineering and summarize major therapeutic applications of the reprogrammed EVs.
abstract_unstemmed	Extracellular vesicles (EVs) have been emerging as a new class of cell-free therapy for the treatment of a variety of diseases, including cancer, tissue injuries, and inflammatory diseases. Reprograming native EVs by genetic engineering and other approaches offers an attractive prospect of extending therapeutic capabilities of EVs beyond their natural functions and properties. In this review article, we survey the state-of-the-art methods of EVs engineering and summarize major therapeutic applications of the reprogrammed EVs.
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title_short	Reprogramming extracellular vesicles with engineered proteins
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author2	Cheng, Qinqin Zhang, Yong
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doi_str	10.1016/j.ymeth.2019.09.017
up_date	2024-07-06T21:35:29.492Z
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Reprogramming extracellular vesicles with engineered proteins

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