Risk factors for cerebrospinal fluid shunt infections during an outbreak: a case–control study

Background: There are few published reports of cerebrospinal fluid (CSF) shunt infection outbreaks. In 2017–2018, British Columbia Children's Hospital (BCCH) experienced an increase in CSF shunt infections co-incident with a move to new operating rooms and a change in shunt catheters used.Aims:...
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Autor*in:	McAlpine, A.K. [verfasserIn] Sauve, L.J. [verfasserIn] Collet, J.C. [verfasserIn] Goldfarb, D.M. [verfasserIn] Guest, E. [verfasserIn] McDonald, P.J. [verfasserIn] Zheng, A. [verfasserIn] Srigley, J.A. [verfasserIn]

Format:	E-Artikel
Sprache:	Englisch

Erschienen:	2019

Schlagwörter:	Outbreak Shunt Infection CSF

Übergeordnetes Werk:	Enthalten in: The journal of hospital infection - Kidlington [u.a.] : Elsevier, 1980, 105, Seite 78-82
Übergeordnetes Werk:	volume:105 ; pages:78-82

DOI / URN:	10.1016/j.jhin.2019.12.012

Katalog-ID:	ELV004059603

Internformat


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100	1		\|a McAlpine, A.K. \|e verfasserin \|4 aut
245	1	0	\|a Risk factors for cerebrospinal fluid shunt infections during an outbreak: a case–control study
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520			\|a Background: There are few published reports of cerebrospinal fluid (CSF) shunt infection outbreaks. In 2017–2018, British Columbia Children's Hospital (BCCH) experienced an increase in CSF shunt infections co-incident with a move to new operating rooms and a change in shunt catheters used.Aims: To describe how an outbreak was detected, investigations were undertaken to determine the cause, risk factors associated with CSF shunt infection during the outbreak, and changes implemented to attempt to control the outbreak.Methods: Retrospective case–control study. Population included patients who underwent new shunt insertion or revision. Univariate logistic regression models were fitted for each of the variables. Associations with P-values <0.2 were considered of potential interest for further investigation.Findings: There were six cases of CSF shunt infection and 19 controls. The causative organism was different in each case. The only risk factors that met the criteria for further investigation were being a neonate at the time of surgery [odds ratio (OR) 9.0, 95% confidence interval (CI) 0.7–125.3, P=0.10] and the presence of gastrointestinal disease (OR 3.8, 95% CI 0.5–26.2, P=0.18). No association was found with the operating room used or the surgical staff. In response to the outbreak, human traffic through the operating rooms was limited, rigid adherence to the wearing of surgical masks was enforced, and return to the previous CSF shunt catheters used was implemented.Conclusion: No modifiable risk factors were associated with CSF shunt infection. After implementation of surgical protocol changes, no further cases of CSF shunt infection linked to the outbreak were identified.
650		4	\|a Outbreak
650		4	\|a Shunt
650		4	\|a Infection
650		4	\|a CSF
700	1		\|a Sauve, L.J. \|e verfasserin \|4 aut
700	1		\|a Collet, J.C. \|e verfasserin \|4 aut
700	1		\|a Goldfarb, D.M. \|e verfasserin \|4 aut
700	1		\|a Guest, E. \|e verfasserin \|4 aut
700	1		\|a McDonald, P.J. \|e verfasserin \|4 aut
700	1		\|a Zheng, A. \|e verfasserin \|4 aut
700	1		\|a Srigley, J.A. \|e verfasserin \|4 aut
773	0	8	\|i Enthalten in \|t The journal of hospital infection \|d Kidlington [u.a.] : Elsevier, 1980 \|g 105, Seite 78-82 \|h Online-Ressource \|w (DE-627)32041986X \|w (DE-600)2002429-0 \|w (DE-576)104344709 \|x 1532-2939 \|7 nnns
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912			\|a GBV_ILN_2048
912			\|a GBV_ILN_2049
912			\|a GBV_ILN_2050
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912			\|a GBV_ILN_2064
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912			\|a GBV_ILN_2111
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912			\|a GBV_ILN_2118
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912			\|a GBV_ILN_4037
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912			\|a GBV_ILN_4126
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912			\|a GBV_ILN_4251
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912			\|a GBV_ILN_4313
912			\|a GBV_ILN_4323
912			\|a GBV_ILN_4324
912			\|a GBV_ILN_4325
912			\|a GBV_ILN_4326
912			\|a GBV_ILN_4333
912			\|a GBV_ILN_4334
912			\|a GBV_ILN_4335
912			\|a GBV_ILN_4338
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936	b	k	\|a 44.17 \|j Stationäres Gesundheitswesen \|j Krankenhauswesen
936	b	k	\|a 44.11 \|j Präventivmedizin
951			\|a AR
952			\|d 105 \|h 78-82

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matchkey_str	article:15322939:2019----::ikatrfreersiafudhnifcindrnaotr
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publishDate	2019
allfields	10.1016/j.jhin.2019.12.012 doi (DE-627)ELV004059603 (ELSEVIER)S0195-6701(19)30533-X DE-627 ger DE-627 rda eng 610 DE-600 44.17 bkl 44.11 bkl McAlpine, A.K. verfasserin aut Risk factors for cerebrospinal fluid shunt infections during an outbreak: a case–control study 2019 nicht spezifiziert zzz rdacontent Computermedien c rdamedia Online-Ressource cr rdacarrier Background: There are few published reports of cerebrospinal fluid (CSF) shunt infection outbreaks. In 2017–2018, British Columbia Children's Hospital (BCCH) experienced an increase in CSF shunt infections co-incident with a move to new operating rooms and a change in shunt catheters used.Aims: To describe how an outbreak was detected, investigations were undertaken to determine the cause, risk factors associated with CSF shunt infection during the outbreak, and changes implemented to attempt to control the outbreak.Methods: Retrospective case–control study. Population included patients who underwent new shunt insertion or revision. Univariate logistic regression models were fitted for each of the variables. Associations with P-values <0.2 were considered of potential interest for further investigation.Findings: There were six cases of CSF shunt infection and 19 controls. The causative organism was different in each case. The only risk factors that met the criteria for further investigation were being a neonate at the time of surgery [odds ratio (OR) 9.0, 95% confidence interval (CI) 0.7–125.3, P=0.10] and the presence of gastrointestinal disease (OR 3.8, 95% CI 0.5–26.2, P=0.18). No association was found with the operating room used or the surgical staff. In response to the outbreak, human traffic through the operating rooms was limited, rigid adherence to the wearing of surgical masks was enforced, and return to the previous CSF shunt catheters used was implemented.Conclusion: No modifiable risk factors were associated with CSF shunt infection. After implementation of surgical protocol changes, no further cases of CSF shunt infection linked to the outbreak were identified. Outbreak Shunt Infection CSF Sauve, L.J. verfasserin aut Collet, J.C. verfasserin aut Goldfarb, D.M. verfasserin aut Guest, E. verfasserin aut McDonald, P.J. verfasserin aut Zheng, A. verfasserin aut Srigley, J.A. verfasserin aut Enthalten in The journal of hospital infection Kidlington [u.a.] : Elsevier, 1980 105, Seite 78-82 Online-Ressource (DE-627)32041986X (DE-600)2002429-0 (DE-576)104344709 1532-2939 nnns volume:105 pages:78-82 GBV_USEFLAG_U SYSFLAG_U GBV_ELV SSG-OLC-PHA GBV_ILN_20 GBV_ILN_22 GBV_ILN_23 GBV_ILN_24 GBV_ILN_31 GBV_ILN_32 GBV_ILN_40 GBV_ILN_60 GBV_ILN_62 GBV_ILN_63 GBV_ILN_65 GBV_ILN_69 GBV_ILN_70 GBV_ILN_73 GBV_ILN_74 GBV_ILN_90 GBV_ILN_95 GBV_ILN_100 GBV_ILN_101 GBV_ILN_105 GBV_ILN_110 GBV_ILN_150 GBV_ILN_151 GBV_ILN_224 GBV_ILN_370 GBV_ILN_602 GBV_ILN_702 GBV_ILN_2003 GBV_ILN_2004 GBV_ILN_2005 GBV_ILN_2011 GBV_ILN_2014 GBV_ILN_2015 GBV_ILN_2020 GBV_ILN_2021 GBV_ILN_2025 GBV_ILN_2027 GBV_ILN_2034 GBV_ILN_2038 GBV_ILN_2044 GBV_ILN_2048 GBV_ILN_2049 GBV_ILN_2050 GBV_ILN_2056 GBV_ILN_2059 GBV_ILN_2061 GBV_ILN_2064 GBV_ILN_2065 GBV_ILN_2068 GBV_ILN_2111 GBV_ILN_2112 GBV_ILN_2113 GBV_ILN_2118 GBV_ILN_2122 GBV_ILN_2129 GBV_ILN_2143 GBV_ILN_2147 GBV_ILN_2148 GBV_ILN_2152 GBV_ILN_2153 GBV_ILN_2190 GBV_ILN_2336 GBV_ILN_2507 GBV_ILN_2522 GBV_ILN_4035 GBV_ILN_4037 GBV_ILN_4112 GBV_ILN_4125 GBV_ILN_4126 GBV_ILN_4242 GBV_ILN_4251 GBV_ILN_4305 GBV_ILN_4313 GBV_ILN_4323 GBV_ILN_4324 GBV_ILN_4325 GBV_ILN_4326 GBV_ILN_4333 GBV_ILN_4334 GBV_ILN_4335 GBV_ILN_4338 GBV_ILN_4393 44.17 Stationäres Gesundheitswesen Krankenhauswesen 44.11 Präventivmedizin AR 105 78-82
spelling	10.1016/j.jhin.2019.12.012 doi (DE-627)ELV004059603 (ELSEVIER)S0195-6701(19)30533-X DE-627 ger DE-627 rda eng 610 DE-600 44.17 bkl 44.11 bkl McAlpine, A.K. verfasserin aut Risk factors for cerebrospinal fluid shunt infections during an outbreak: a case–control study 2019 nicht spezifiziert zzz rdacontent Computermedien c rdamedia Online-Ressource cr rdacarrier Background: There are few published reports of cerebrospinal fluid (CSF) shunt infection outbreaks. In 2017–2018, British Columbia Children's Hospital (BCCH) experienced an increase in CSF shunt infections co-incident with a move to new operating rooms and a change in shunt catheters used.Aims: To describe how an outbreak was detected, investigations were undertaken to determine the cause, risk factors associated with CSF shunt infection during the outbreak, and changes implemented to attempt to control the outbreak.Methods: Retrospective case–control study. Population included patients who underwent new shunt insertion or revision. Univariate logistic regression models were fitted for each of the variables. Associations with P-values <0.2 were considered of potential interest for further investigation.Findings: There were six cases of CSF shunt infection and 19 controls. The causative organism was different in each case. The only risk factors that met the criteria for further investigation were being a neonate at the time of surgery [odds ratio (OR) 9.0, 95% confidence interval (CI) 0.7–125.3, P=0.10] and the presence of gastrointestinal disease (OR 3.8, 95% CI 0.5–26.2, P=0.18). No association was found with the operating room used or the surgical staff. In response to the outbreak, human traffic through the operating rooms was limited, rigid adherence to the wearing of surgical masks was enforced, and return to the previous CSF shunt catheters used was implemented.Conclusion: No modifiable risk factors were associated with CSF shunt infection. After implementation of surgical protocol changes, no further cases of CSF shunt infection linked to the outbreak were identified. Outbreak Shunt Infection CSF Sauve, L.J. verfasserin aut Collet, J.C. verfasserin aut Goldfarb, D.M. verfasserin aut Guest, E. verfasserin aut McDonald, P.J. verfasserin aut Zheng, A. verfasserin aut Srigley, J.A. verfasserin aut Enthalten in The journal of hospital infection Kidlington [u.a.] : Elsevier, 1980 105, Seite 78-82 Online-Ressource (DE-627)32041986X (DE-600)2002429-0 (DE-576)104344709 1532-2939 nnns volume:105 pages:78-82 GBV_USEFLAG_U SYSFLAG_U GBV_ELV SSG-OLC-PHA GBV_ILN_20 GBV_ILN_22 GBV_ILN_23 GBV_ILN_24 GBV_ILN_31 GBV_ILN_32 GBV_ILN_40 GBV_ILN_60 GBV_ILN_62 GBV_ILN_63 GBV_ILN_65 GBV_ILN_69 GBV_ILN_70 GBV_ILN_73 GBV_ILN_74 GBV_ILN_90 GBV_ILN_95 GBV_ILN_100 GBV_ILN_101 GBV_ILN_105 GBV_ILN_110 GBV_ILN_150 GBV_ILN_151 GBV_ILN_224 GBV_ILN_370 GBV_ILN_602 GBV_ILN_702 GBV_ILN_2003 GBV_ILN_2004 GBV_ILN_2005 GBV_ILN_2011 GBV_ILN_2014 GBV_ILN_2015 GBV_ILN_2020 GBV_ILN_2021 GBV_ILN_2025 GBV_ILN_2027 GBV_ILN_2034 GBV_ILN_2038 GBV_ILN_2044 GBV_ILN_2048 GBV_ILN_2049 GBV_ILN_2050 GBV_ILN_2056 GBV_ILN_2059 GBV_ILN_2061 GBV_ILN_2064 GBV_ILN_2065 GBV_ILN_2068 GBV_ILN_2111 GBV_ILN_2112 GBV_ILN_2113 GBV_ILN_2118 GBV_ILN_2122 GBV_ILN_2129 GBV_ILN_2143 GBV_ILN_2147 GBV_ILN_2148 GBV_ILN_2152 GBV_ILN_2153 GBV_ILN_2190 GBV_ILN_2336 GBV_ILN_2507 GBV_ILN_2522 GBV_ILN_4035 GBV_ILN_4037 GBV_ILN_4112 GBV_ILN_4125 GBV_ILN_4126 GBV_ILN_4242 GBV_ILN_4251 GBV_ILN_4305 GBV_ILN_4313 GBV_ILN_4323 GBV_ILN_4324 GBV_ILN_4325 GBV_ILN_4326 GBV_ILN_4333 GBV_ILN_4334 GBV_ILN_4335 GBV_ILN_4338 GBV_ILN_4393 44.17 Stationäres Gesundheitswesen Krankenhauswesen 44.11 Präventivmedizin AR 105 78-82
allfields_unstemmed	10.1016/j.jhin.2019.12.012 doi (DE-627)ELV004059603 (ELSEVIER)S0195-6701(19)30533-X DE-627 ger DE-627 rda eng 610 DE-600 44.17 bkl 44.11 bkl McAlpine, A.K. verfasserin aut Risk factors for cerebrospinal fluid shunt infections during an outbreak: a case–control study 2019 nicht spezifiziert zzz rdacontent Computermedien c rdamedia Online-Ressource cr rdacarrier Background: There are few published reports of cerebrospinal fluid (CSF) shunt infection outbreaks. In 2017–2018, British Columbia Children's Hospital (BCCH) experienced an increase in CSF shunt infections co-incident with a move to new operating rooms and a change in shunt catheters used.Aims: To describe how an outbreak was detected, investigations were undertaken to determine the cause, risk factors associated with CSF shunt infection during the outbreak, and changes implemented to attempt to control the outbreak.Methods: Retrospective case–control study. Population included patients who underwent new shunt insertion or revision. Univariate logistic regression models were fitted for each of the variables. Associations with P-values <0.2 were considered of potential interest for further investigation.Findings: There were six cases of CSF shunt infection and 19 controls. The causative organism was different in each case. The only risk factors that met the criteria for further investigation were being a neonate at the time of surgery [odds ratio (OR) 9.0, 95% confidence interval (CI) 0.7–125.3, P=0.10] and the presence of gastrointestinal disease (OR 3.8, 95% CI 0.5–26.2, P=0.18). No association was found with the operating room used or the surgical staff. In response to the outbreak, human traffic through the operating rooms was limited, rigid adherence to the wearing of surgical masks was enforced, and return to the previous CSF shunt catheters used was implemented.Conclusion: No modifiable risk factors were associated with CSF shunt infection. After implementation of surgical protocol changes, no further cases of CSF shunt infection linked to the outbreak were identified. Outbreak Shunt Infection CSF Sauve, L.J. verfasserin aut Collet, J.C. verfasserin aut Goldfarb, D.M. verfasserin aut Guest, E. verfasserin aut McDonald, P.J. verfasserin aut Zheng, A. verfasserin aut Srigley, J.A. verfasserin aut Enthalten in The journal of hospital infection Kidlington [u.a.] : Elsevier, 1980 105, Seite 78-82 Online-Ressource (DE-627)32041986X (DE-600)2002429-0 (DE-576)104344709 1532-2939 nnns volume:105 pages:78-82 GBV_USEFLAG_U SYSFLAG_U GBV_ELV SSG-OLC-PHA GBV_ILN_20 GBV_ILN_22 GBV_ILN_23 GBV_ILN_24 GBV_ILN_31 GBV_ILN_32 GBV_ILN_40 GBV_ILN_60 GBV_ILN_62 GBV_ILN_63 GBV_ILN_65 GBV_ILN_69 GBV_ILN_70 GBV_ILN_73 GBV_ILN_74 GBV_ILN_90 GBV_ILN_95 GBV_ILN_100 GBV_ILN_101 GBV_ILN_105 GBV_ILN_110 GBV_ILN_150 GBV_ILN_151 GBV_ILN_224 GBV_ILN_370 GBV_ILN_602 GBV_ILN_702 GBV_ILN_2003 GBV_ILN_2004 GBV_ILN_2005 GBV_ILN_2011 GBV_ILN_2014 GBV_ILN_2015 GBV_ILN_2020 GBV_ILN_2021 GBV_ILN_2025 GBV_ILN_2027 GBV_ILN_2034 GBV_ILN_2038 GBV_ILN_2044 GBV_ILN_2048 GBV_ILN_2049 GBV_ILN_2050 GBV_ILN_2056 GBV_ILN_2059 GBV_ILN_2061 GBV_ILN_2064 GBV_ILN_2065 GBV_ILN_2068 GBV_ILN_2111 GBV_ILN_2112 GBV_ILN_2113 GBV_ILN_2118 GBV_ILN_2122 GBV_ILN_2129 GBV_ILN_2143 GBV_ILN_2147 GBV_ILN_2148 GBV_ILN_2152 GBV_ILN_2153 GBV_ILN_2190 GBV_ILN_2336 GBV_ILN_2507 GBV_ILN_2522 GBV_ILN_4035 GBV_ILN_4037 GBV_ILN_4112 GBV_ILN_4125 GBV_ILN_4126 GBV_ILN_4242 GBV_ILN_4251 GBV_ILN_4305 GBV_ILN_4313 GBV_ILN_4323 GBV_ILN_4324 GBV_ILN_4325 GBV_ILN_4326 GBV_ILN_4333 GBV_ILN_4334 GBV_ILN_4335 GBV_ILN_4338 GBV_ILN_4393 44.17 Stationäres Gesundheitswesen Krankenhauswesen 44.11 Präventivmedizin AR 105 78-82
allfieldsGer	10.1016/j.jhin.2019.12.012 doi (DE-627)ELV004059603 (ELSEVIER)S0195-6701(19)30533-X DE-627 ger DE-627 rda eng 610 DE-600 44.17 bkl 44.11 bkl McAlpine, A.K. verfasserin aut Risk factors for cerebrospinal fluid shunt infections during an outbreak: a case–control study 2019 nicht spezifiziert zzz rdacontent Computermedien c rdamedia Online-Ressource cr rdacarrier Background: There are few published reports of cerebrospinal fluid (CSF) shunt infection outbreaks. In 2017–2018, British Columbia Children's Hospital (BCCH) experienced an increase in CSF shunt infections co-incident with a move to new operating rooms and a change in shunt catheters used.Aims: To describe how an outbreak was detected, investigations were undertaken to determine the cause, risk factors associated with CSF shunt infection during the outbreak, and changes implemented to attempt to control the outbreak.Methods: Retrospective case–control study. Population included patients who underwent new shunt insertion or revision. Univariate logistic regression models were fitted for each of the variables. Associations with P-values <0.2 were considered of potential interest for further investigation.Findings: There were six cases of CSF shunt infection and 19 controls. The causative organism was different in each case. The only risk factors that met the criteria for further investigation were being a neonate at the time of surgery [odds ratio (OR) 9.0, 95% confidence interval (CI) 0.7–125.3, P=0.10] and the presence of gastrointestinal disease (OR 3.8, 95% CI 0.5–26.2, P=0.18). No association was found with the operating room used or the surgical staff. In response to the outbreak, human traffic through the operating rooms was limited, rigid adherence to the wearing of surgical masks was enforced, and return to the previous CSF shunt catheters used was implemented.Conclusion: No modifiable risk factors were associated with CSF shunt infection. After implementation of surgical protocol changes, no further cases of CSF shunt infection linked to the outbreak were identified. Outbreak Shunt Infection CSF Sauve, L.J. verfasserin aut Collet, J.C. verfasserin aut Goldfarb, D.M. verfasserin aut Guest, E. verfasserin aut McDonald, P.J. verfasserin aut Zheng, A. verfasserin aut Srigley, J.A. verfasserin aut Enthalten in The journal of hospital infection Kidlington [u.a.] : Elsevier, 1980 105, Seite 78-82 Online-Ressource (DE-627)32041986X (DE-600)2002429-0 (DE-576)104344709 1532-2939 nnns volume:105 pages:78-82 GBV_USEFLAG_U SYSFLAG_U GBV_ELV SSG-OLC-PHA GBV_ILN_20 GBV_ILN_22 GBV_ILN_23 GBV_ILN_24 GBV_ILN_31 GBV_ILN_32 GBV_ILN_40 GBV_ILN_60 GBV_ILN_62 GBV_ILN_63 GBV_ILN_65 GBV_ILN_69 GBV_ILN_70 GBV_ILN_73 GBV_ILN_74 GBV_ILN_90 GBV_ILN_95 GBV_ILN_100 GBV_ILN_101 GBV_ILN_105 GBV_ILN_110 GBV_ILN_150 GBV_ILN_151 GBV_ILN_224 GBV_ILN_370 GBV_ILN_602 GBV_ILN_702 GBV_ILN_2003 GBV_ILN_2004 GBV_ILN_2005 GBV_ILN_2011 GBV_ILN_2014 GBV_ILN_2015 GBV_ILN_2020 GBV_ILN_2021 GBV_ILN_2025 GBV_ILN_2027 GBV_ILN_2034 GBV_ILN_2038 GBV_ILN_2044 GBV_ILN_2048 GBV_ILN_2049 GBV_ILN_2050 GBV_ILN_2056 GBV_ILN_2059 GBV_ILN_2061 GBV_ILN_2064 GBV_ILN_2065 GBV_ILN_2068 GBV_ILN_2111 GBV_ILN_2112 GBV_ILN_2113 GBV_ILN_2118 GBV_ILN_2122 GBV_ILN_2129 GBV_ILN_2143 GBV_ILN_2147 GBV_ILN_2148 GBV_ILN_2152 GBV_ILN_2153 GBV_ILN_2190 GBV_ILN_2336 GBV_ILN_2507 GBV_ILN_2522 GBV_ILN_4035 GBV_ILN_4037 GBV_ILN_4112 GBV_ILN_4125 GBV_ILN_4126 GBV_ILN_4242 GBV_ILN_4251 GBV_ILN_4305 GBV_ILN_4313 GBV_ILN_4323 GBV_ILN_4324 GBV_ILN_4325 GBV_ILN_4326 GBV_ILN_4333 GBV_ILN_4334 GBV_ILN_4335 GBV_ILN_4338 GBV_ILN_4393 44.17 Stationäres Gesundheitswesen Krankenhauswesen 44.11 Präventivmedizin AR 105 78-82
allfieldsSound	10.1016/j.jhin.2019.12.012 doi (DE-627)ELV004059603 (ELSEVIER)S0195-6701(19)30533-X DE-627 ger DE-627 rda eng 610 DE-600 44.17 bkl 44.11 bkl McAlpine, A.K. verfasserin aut Risk factors for cerebrospinal fluid shunt infections during an outbreak: a case–control study 2019 nicht spezifiziert zzz rdacontent Computermedien c rdamedia Online-Ressource cr rdacarrier Background: There are few published reports of cerebrospinal fluid (CSF) shunt infection outbreaks. In 2017–2018, British Columbia Children's Hospital (BCCH) experienced an increase in CSF shunt infections co-incident with a move to new operating rooms and a change in shunt catheters used.Aims: To describe how an outbreak was detected, investigations were undertaken to determine the cause, risk factors associated with CSF shunt infection during the outbreak, and changes implemented to attempt to control the outbreak.Methods: Retrospective case–control study. Population included patients who underwent new shunt insertion or revision. Univariate logistic regression models were fitted for each of the variables. Associations with P-values <0.2 were considered of potential interest for further investigation.Findings: There were six cases of CSF shunt infection and 19 controls. The causative organism was different in each case. The only risk factors that met the criteria for further investigation were being a neonate at the time of surgery [odds ratio (OR) 9.0, 95% confidence interval (CI) 0.7–125.3, P=0.10] and the presence of gastrointestinal disease (OR 3.8, 95% CI 0.5–26.2, P=0.18). No association was found with the operating room used or the surgical staff. In response to the outbreak, human traffic through the operating rooms was limited, rigid adherence to the wearing of surgical masks was enforced, and return to the previous CSF shunt catheters used was implemented.Conclusion: No modifiable risk factors were associated with CSF shunt infection. After implementation of surgical protocol changes, no further cases of CSF shunt infection linked to the outbreak were identified. Outbreak Shunt Infection CSF Sauve, L.J. verfasserin aut Collet, J.C. verfasserin aut Goldfarb, D.M. verfasserin aut Guest, E. verfasserin aut McDonald, P.J. verfasserin aut Zheng, A. verfasserin aut Srigley, J.A. verfasserin aut Enthalten in The journal of hospital infection Kidlington [u.a.] : Elsevier, 1980 105, Seite 78-82 Online-Ressource (DE-627)32041986X (DE-600)2002429-0 (DE-576)104344709 1532-2939 nnns volume:105 pages:78-82 GBV_USEFLAG_U SYSFLAG_U GBV_ELV SSG-OLC-PHA GBV_ILN_20 GBV_ILN_22 GBV_ILN_23 GBV_ILN_24 GBV_ILN_31 GBV_ILN_32 GBV_ILN_40 GBV_ILN_60 GBV_ILN_62 GBV_ILN_63 GBV_ILN_65 GBV_ILN_69 GBV_ILN_70 GBV_ILN_73 GBV_ILN_74 GBV_ILN_90 GBV_ILN_95 GBV_ILN_100 GBV_ILN_101 GBV_ILN_105 GBV_ILN_110 GBV_ILN_150 GBV_ILN_151 GBV_ILN_224 GBV_ILN_370 GBV_ILN_602 GBV_ILN_702 GBV_ILN_2003 GBV_ILN_2004 GBV_ILN_2005 GBV_ILN_2011 GBV_ILN_2014 GBV_ILN_2015 GBV_ILN_2020 GBV_ILN_2021 GBV_ILN_2025 GBV_ILN_2027 GBV_ILN_2034 GBV_ILN_2038 GBV_ILN_2044 GBV_ILN_2048 GBV_ILN_2049 GBV_ILN_2050 GBV_ILN_2056 GBV_ILN_2059 GBV_ILN_2061 GBV_ILN_2064 GBV_ILN_2065 GBV_ILN_2068 GBV_ILN_2111 GBV_ILN_2112 GBV_ILN_2113 GBV_ILN_2118 GBV_ILN_2122 GBV_ILN_2129 GBV_ILN_2143 GBV_ILN_2147 GBV_ILN_2148 GBV_ILN_2152 GBV_ILN_2153 GBV_ILN_2190 GBV_ILN_2336 GBV_ILN_2507 GBV_ILN_2522 GBV_ILN_4035 GBV_ILN_4037 GBV_ILN_4112 GBV_ILN_4125 GBV_ILN_4126 GBV_ILN_4242 GBV_ILN_4251 GBV_ILN_4305 GBV_ILN_4313 GBV_ILN_4323 GBV_ILN_4324 GBV_ILN_4325 GBV_ILN_4326 GBV_ILN_4333 GBV_ILN_4334 GBV_ILN_4335 GBV_ILN_4338 GBV_ILN_4393 44.17 Stationäres Gesundheitswesen Krankenhauswesen 44.11 Präventivmedizin AR 105 78-82
language	English
source	Enthalten in The journal of hospital infection 105, Seite 78-82 volume:105 pages:78-82
sourceStr	Enthalten in The journal of hospital infection 105, Seite 78-82 volume:105 pages:78-82
format_phy_str_mv	Article
bklname	Stationäres Gesundheitswesen Krankenhauswesen Präventivmedizin
institution	findex.gbv.de
topic_facet	Outbreak Shunt Infection CSF
dewey-raw	610
isfreeaccess_bool	false
container_title	The journal of hospital infection
authorswithroles_txt_mv	McAlpine, A.K. @@aut@@ Sauve, L.J. @@aut@@ Collet, J.C. @@aut@@ Goldfarb, D.M. @@aut@@ Guest, E. @@aut@@ McDonald, P.J. @@aut@@ Zheng, A. @@aut@@ Srigley, J.A. @@aut@@
publishDateDaySort_date	2019-01-01T00:00:00Z
hierarchy_top_id	32041986X
dewey-sort	3610
id	ELV004059603
language_de	englisch
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In 2017–2018, British Columbia Children's Hospital (BCCH) experienced an increase in CSF shunt infections co-incident with a move to new operating rooms and a change in shunt catheters used.Aims: To describe how an outbreak was detected, investigations were undertaken to determine the cause, risk factors associated with CSF shunt infection during the outbreak, and changes implemented to attempt to control the outbreak.Methods: Retrospective case–control study. Population included patients who underwent new shunt insertion or revision. Univariate logistic regression models were fitted for each of the variables. Associations with P-values <0.2 were considered of potential interest for further investigation.Findings: There were six cases of CSF shunt infection and 19 controls. The causative organism was different in each case. The only risk factors that met the criteria for further investigation were being a neonate at the time of surgery [odds ratio (OR) 9.0, 95% confidence interval (CI) 0.7–125.3, P=0.10] and the presence of gastrointestinal disease (OR 3.8, 95% CI 0.5–26.2, P=0.18). No association was found with the operating room used or the surgical staff. In response to the outbreak, human traffic through the operating rooms was limited, rigid adherence to the wearing of surgical masks was enforced, and return to the previous CSF shunt catheters used was implemented.Conclusion: No modifiable risk factors were associated with CSF shunt infection. 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author	McAlpine, A.K.
spellingShingle	McAlpine, A.K. ddc 610 bkl 44.17 bkl 44.11 misc Outbreak misc Shunt misc Infection misc CSF Risk factors for cerebrospinal fluid shunt infections during an outbreak: a case–control study
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topic_title	610 DE-600 44.17 bkl 44.11 bkl Risk factors for cerebrospinal fluid shunt infections during an outbreak: a case–control study Outbreak Shunt Infection CSF
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title	Risk factors for cerebrospinal fluid shunt infections during an outbreak: a case–control study
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title_full	Risk factors for cerebrospinal fluid shunt infections during an outbreak: a case–control study
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title_sort	risk factors for cerebrospinal fluid shunt infections during an outbreak: a case–control study
title_auth	Risk factors for cerebrospinal fluid shunt infections during an outbreak: a case–control study
abstract	Background: There are few published reports of cerebrospinal fluid (CSF) shunt infection outbreaks. In 2017–2018, British Columbia Children's Hospital (BCCH) experienced an increase in CSF shunt infections co-incident with a move to new operating rooms and a change in shunt catheters used.Aims: To describe how an outbreak was detected, investigations were undertaken to determine the cause, risk factors associated with CSF shunt infection during the outbreak, and changes implemented to attempt to control the outbreak.Methods: Retrospective case–control study. Population included patients who underwent new shunt insertion or revision. Univariate logistic regression models were fitted for each of the variables. Associations with P-values <0.2 were considered of potential interest for further investigation.Findings: There were six cases of CSF shunt infection and 19 controls. The causative organism was different in each case. The only risk factors that met the criteria for further investigation were being a neonate at the time of surgery [odds ratio (OR) 9.0, 95% confidence interval (CI) 0.7–125.3, P=0.10] and the presence of gastrointestinal disease (OR 3.8, 95% CI 0.5–26.2, P=0.18). No association was found with the operating room used or the surgical staff. In response to the outbreak, human traffic through the operating rooms was limited, rigid adherence to the wearing of surgical masks was enforced, and return to the previous CSF shunt catheters used was implemented.Conclusion: No modifiable risk factors were associated with CSF shunt infection. After implementation of surgical protocol changes, no further cases of CSF shunt infection linked to the outbreak were identified.
abstractGer	Background: There are few published reports of cerebrospinal fluid (CSF) shunt infection outbreaks. In 2017–2018, British Columbia Children's Hospital (BCCH) experienced an increase in CSF shunt infections co-incident with a move to new operating rooms and a change in shunt catheters used.Aims: To describe how an outbreak was detected, investigations were undertaken to determine the cause, risk factors associated with CSF shunt infection during the outbreak, and changes implemented to attempt to control the outbreak.Methods: Retrospective case–control study. Population included patients who underwent new shunt insertion or revision. Univariate logistic regression models were fitted for each of the variables. Associations with P-values <0.2 were considered of potential interest for further investigation.Findings: There were six cases of CSF shunt infection and 19 controls. The causative organism was different in each case. The only risk factors that met the criteria for further investigation were being a neonate at the time of surgery [odds ratio (OR) 9.0, 95% confidence interval (CI) 0.7–125.3, P=0.10] and the presence of gastrointestinal disease (OR 3.8, 95% CI 0.5–26.2, P=0.18). No association was found with the operating room used or the surgical staff. In response to the outbreak, human traffic through the operating rooms was limited, rigid adherence to the wearing of surgical masks was enforced, and return to the previous CSF shunt catheters used was implemented.Conclusion: No modifiable risk factors were associated with CSF shunt infection. After implementation of surgical protocol changes, no further cases of CSF shunt infection linked to the outbreak were identified.
abstract_unstemmed	Background: There are few published reports of cerebrospinal fluid (CSF) shunt infection outbreaks. In 2017–2018, British Columbia Children's Hospital (BCCH) experienced an increase in CSF shunt infections co-incident with a move to new operating rooms and a change in shunt catheters used.Aims: To describe how an outbreak was detected, investigations were undertaken to determine the cause, risk factors associated with CSF shunt infection during the outbreak, and changes implemented to attempt to control the outbreak.Methods: Retrospective case–control study. Population included patients who underwent new shunt insertion or revision. Univariate logistic regression models were fitted for each of the variables. Associations with P-values <0.2 were considered of potential interest for further investigation.Findings: There were six cases of CSF shunt infection and 19 controls. The causative organism was different in each case. The only risk factors that met the criteria for further investigation were being a neonate at the time of surgery [odds ratio (OR) 9.0, 95% confidence interval (CI) 0.7–125.3, P=0.10] and the presence of gastrointestinal disease (OR 3.8, 95% CI 0.5–26.2, P=0.18). No association was found with the operating room used or the surgical staff. In response to the outbreak, human traffic through the operating rooms was limited, rigid adherence to the wearing of surgical masks was enforced, and return to the previous CSF shunt catheters used was implemented.Conclusion: No modifiable risk factors were associated with CSF shunt infection. After implementation of surgical protocol changes, no further cases of CSF shunt infection linked to the outbreak were identified.
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title_short	Risk factors for cerebrospinal fluid shunt infections during an outbreak: a case–control study
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author2	Sauve, L.J. Collet, J.C. Goldfarb, D.M. Guest, E. McDonald, P.J. Zheng, A. Srigley, J.A.
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up_date	2024-07-06T21:42:42.288Z
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Risk factors for cerebrospinal fluid shunt infections during an outbreak: a case–control study

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