Structural modification of nonspecific thiazole orange for ligand-DNA interaction study: Understanding the ligand recognition selectivity towards G4-DNA over duplex-DNA

The study of ligand interactions with nucleic acid structures such as G-quadruplexes versus double-stranded DNA is important because these interactions are fundamental for many intracellular processes. In the investigation of ligand-DNA binding process, achieving high fluorescent signal discriminati...
Ausführliche Beschreibung

Gespeichert in:
Autor*in:

Zhu, Yiwen [verfasserIn]

Hou, Jinqiang [verfasserIn]

Huang, Xuan-He [verfasserIn]

Zhong, Dong-Xiao [verfasserIn]

Long, Wei [verfasserIn]

Liu, Wenjie [verfasserIn]

Lu, Yu-Jing [verfasserIn]

Zhang, Kun [verfasserIn]

Wong, Wing-Leung [verfasserIn]

Format:

E-Artikel

Sprache:

Englisch

Erschienen:

2020

Schlagwörter:

Fluorescent binding ligand

Ligand-DNA interaction

G-quadruplex DNA recognition

Molecular docking

Übergeordnetes Werk:

Enthalten in: Journal of luminescence - New York, NY [u.a.] : Elsevier, 1970, 226

Übergeordnetes Werk:

volume:226

DOI / URN:

10.1016/j.jlumin.2020.117488

Katalog-ID:

ELV004479726

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