Prenatal exposure to benzotraizoles and benzothiazoles in relation to fetal and birth size: A longitudinal study
The presence of benzotriazoles and benzothiazoles (BTs) in maternal urine and amniotic fluid indicated the widespread fetal exposure to the contaminants. We investigated the associations of prenatal BTs exposure with fetal and birth size and explored the window of susceptibility. Participants consis...
Ausführliche Beschreibung
Autor*in: |
Zhou, Yanqiu [verfasserIn] Li, Ying [verfasserIn] Xu, Shunqing [verfasserIn] Liao, Jiaqiang [verfasserIn] Zhang, Hongna [verfasserIn] Li, Jiufeng [verfasserIn] Hong, Yanjun [verfasserIn] Xia, Wei [verfasserIn] Cai, Zongwei [verfasserIn] |
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Format: |
E-Artikel |
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Sprache: |
Englisch |
Erschienen: |
2020 |
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Schlagwörter: |
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Übergeordnetes Werk: |
Enthalten in: Journal of hazardous materials - New York, NY [u.a.] : Science Direct, 1976, 398 |
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Übergeordnetes Werk: |
volume:398 |
DOI / URN: |
10.1016/j.jhazmat.2020.122828 |
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Katalog-ID: |
ELV004553411 |
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245 | 1 | 0 | |a Prenatal exposure to benzotraizoles and benzothiazoles in relation to fetal and birth size: A longitudinal study |
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520 | |a The presence of benzotriazoles and benzothiazoles (BTs) in maternal urine and amniotic fluid indicated the widespread fetal exposure to the contaminants. We investigated the associations of prenatal BTs exposure with fetal and birth size and explored the window of susceptibility. Participants consisted of 856 mother-infant pairs drawn from a prospective birth cohort between 2014 and 2015 in Wuhan, China. Prenatal BTs exposure were measured in multiple urine samples collected across three trimesters. We observed positive associations between prenatal exposure to specific BTs (e.g., 1-H-benzotriazole, 1-hydroxy-benzotriazole and 2-amino-benzothiazole) and femur length (FL) and birth length z-scores among girls. In boys, a 2-fold increase of averaged concentration of urinary benzothiazole (BTH) was associated with decrement in FL (β = -0.068, p < 0.001) and birth length (β = -0.055, p = 0.005) z-scores. Further analysis indicated that the negative associations between urinary concentrations of BTH and birth length z-score among boys were observed at exposure measurement in 25–35 gestational weeks. This study reported the associations between prenatal exposure to BTs and fetal and birth size, suggests the associations maybe in a sex-specific manner and the window of exposure may influence susceptibility. These findings require replication in future research. | ||
650 | 4 | |a Benzotriazole | |
650 | 4 | |a Benzothiazole | |
650 | 4 | |a Fetal and birth size | |
650 | 4 | |a Longitudinal | |
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700 | 1 | |a Xu, Shunqing |e verfasserin |4 aut | |
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700 | 1 | |a Zhang, Hongna |e verfasserin |4 aut | |
700 | 1 | |a Li, Jiufeng |e verfasserin |4 aut | |
700 | 1 | |a Hong, Yanjun |e verfasserin |4 aut | |
700 | 1 | |a Xia, Wei |e verfasserin |4 aut | |
700 | 1 | |a Cai, Zongwei |e verfasserin |4 aut | |
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10.1016/j.jhazmat.2020.122828 doi (DE-627)ELV004553411 (ELSEVIER)S0304-3894(20)30817-7 DE-627 ger DE-627 rda eng 530 DE-600 43.13 bkl 50.17 bkl 58.53 bkl Zhou, Yanqiu verfasserin aut Prenatal exposure to benzotraizoles and benzothiazoles in relation to fetal and birth size: A longitudinal study 2020 nicht spezifiziert zzz rdacontent Computermedien c rdamedia Online-Ressource cr rdacarrier The presence of benzotriazoles and benzothiazoles (BTs) in maternal urine and amniotic fluid indicated the widespread fetal exposure to the contaminants. We investigated the associations of prenatal BTs exposure with fetal and birth size and explored the window of susceptibility. Participants consisted of 856 mother-infant pairs drawn from a prospective birth cohort between 2014 and 2015 in Wuhan, China. Prenatal BTs exposure were measured in multiple urine samples collected across three trimesters. We observed positive associations between prenatal exposure to specific BTs (e.g., 1-H-benzotriazole, 1-hydroxy-benzotriazole and 2-amino-benzothiazole) and femur length (FL) and birth length z-scores among girls. In boys, a 2-fold increase of averaged concentration of urinary benzothiazole (BTH) was associated with decrement in FL (β = -0.068, p < 0.001) and birth length (β = -0.055, p = 0.005) z-scores. Further analysis indicated that the negative associations between urinary concentrations of BTH and birth length z-score among boys were observed at exposure measurement in 25–35 gestational weeks. This study reported the associations between prenatal exposure to BTs and fetal and birth size, suggests the associations maybe in a sex-specific manner and the window of exposure may influence susceptibility. These findings require replication in future research. Benzotriazole Benzothiazole Fetal and birth size Longitudinal Li, Ying verfasserin aut Xu, Shunqing verfasserin aut Liao, Jiaqiang verfasserin aut Zhang, Hongna verfasserin aut Li, Jiufeng verfasserin aut Hong, Yanjun verfasserin aut Xia, Wei verfasserin aut Cai, Zongwei verfasserin aut Enthalten in Journal of hazardous materials New York, NY [u.a.] : Science Direct, 1976 398 Online-Ressource (DE-627)302467904 (DE-600)1491302-1 (DE-576)259483893 1873-3336 nnns volume:398 GBV_USEFLAG_U SYSFLAG_U GBV_ELV SSG-OPC-GGO GBV_ILN_20 GBV_ILN_22 GBV_ILN_23 GBV_ILN_24 GBV_ILN_31 GBV_ILN_32 GBV_ILN_40 GBV_ILN_60 GBV_ILN_62 GBV_ILN_63 GBV_ILN_65 GBV_ILN_69 GBV_ILN_70 GBV_ILN_73 GBV_ILN_74 GBV_ILN_90 GBV_ILN_95 GBV_ILN_100 GBV_ILN_101 GBV_ILN_105 GBV_ILN_110 GBV_ILN_150 GBV_ILN_151 GBV_ILN_224 GBV_ILN_370 GBV_ILN_602 GBV_ILN_702 GBV_ILN_2003 GBV_ILN_2004 GBV_ILN_2005 GBV_ILN_2011 GBV_ILN_2014 GBV_ILN_2015 GBV_ILN_2020 GBV_ILN_2021 GBV_ILN_2025 GBV_ILN_2027 GBV_ILN_2034 GBV_ILN_2038 GBV_ILN_2044 GBV_ILN_2048 GBV_ILN_2049 GBV_ILN_2050 GBV_ILN_2056 GBV_ILN_2059 GBV_ILN_2061 GBV_ILN_2064 GBV_ILN_2065 GBV_ILN_2068 GBV_ILN_2111 GBV_ILN_2112 GBV_ILN_2113 GBV_ILN_2118 GBV_ILN_2122 GBV_ILN_2129 GBV_ILN_2143 GBV_ILN_2147 GBV_ILN_2148 GBV_ILN_2152 GBV_ILN_2153 GBV_ILN_2190 GBV_ILN_2336 GBV_ILN_2507 GBV_ILN_2522 GBV_ILN_4035 GBV_ILN_4037 GBV_ILN_4112 GBV_ILN_4125 GBV_ILN_4126 GBV_ILN_4242 GBV_ILN_4251 GBV_ILN_4305 GBV_ILN_4313 GBV_ILN_4323 GBV_ILN_4324 GBV_ILN_4326 GBV_ILN_4333 GBV_ILN_4334 GBV_ILN_4335 GBV_ILN_4338 GBV_ILN_4393 43.13 Umwelttoxikologie 50.17 Sicherheitstechnik 58.53 Abfallwirtschaft AR 398 |
spelling |
10.1016/j.jhazmat.2020.122828 doi (DE-627)ELV004553411 (ELSEVIER)S0304-3894(20)30817-7 DE-627 ger DE-627 rda eng 530 DE-600 43.13 bkl 50.17 bkl 58.53 bkl Zhou, Yanqiu verfasserin aut Prenatal exposure to benzotraizoles and benzothiazoles in relation to fetal and birth size: A longitudinal study 2020 nicht spezifiziert zzz rdacontent Computermedien c rdamedia Online-Ressource cr rdacarrier The presence of benzotriazoles and benzothiazoles (BTs) in maternal urine and amniotic fluid indicated the widespread fetal exposure to the contaminants. We investigated the associations of prenatal BTs exposure with fetal and birth size and explored the window of susceptibility. Participants consisted of 856 mother-infant pairs drawn from a prospective birth cohort between 2014 and 2015 in Wuhan, China. Prenatal BTs exposure were measured in multiple urine samples collected across three trimesters. We observed positive associations between prenatal exposure to specific BTs (e.g., 1-H-benzotriazole, 1-hydroxy-benzotriazole and 2-amino-benzothiazole) and femur length (FL) and birth length z-scores among girls. In boys, a 2-fold increase of averaged concentration of urinary benzothiazole (BTH) was associated with decrement in FL (β = -0.068, p < 0.001) and birth length (β = -0.055, p = 0.005) z-scores. Further analysis indicated that the negative associations between urinary concentrations of BTH and birth length z-score among boys were observed at exposure measurement in 25–35 gestational weeks. This study reported the associations between prenatal exposure to BTs and fetal and birth size, suggests the associations maybe in a sex-specific manner and the window of exposure may influence susceptibility. These findings require replication in future research. Benzotriazole Benzothiazole Fetal and birth size Longitudinal Li, Ying verfasserin aut Xu, Shunqing verfasserin aut Liao, Jiaqiang verfasserin aut Zhang, Hongna verfasserin aut Li, Jiufeng verfasserin aut Hong, Yanjun verfasserin aut Xia, Wei verfasserin aut Cai, Zongwei verfasserin aut Enthalten in Journal of hazardous materials New York, NY [u.a.] : Science Direct, 1976 398 Online-Ressource (DE-627)302467904 (DE-600)1491302-1 (DE-576)259483893 1873-3336 nnns volume:398 GBV_USEFLAG_U SYSFLAG_U GBV_ELV SSG-OPC-GGO GBV_ILN_20 GBV_ILN_22 GBV_ILN_23 GBV_ILN_24 GBV_ILN_31 GBV_ILN_32 GBV_ILN_40 GBV_ILN_60 GBV_ILN_62 GBV_ILN_63 GBV_ILN_65 GBV_ILN_69 GBV_ILN_70 GBV_ILN_73 GBV_ILN_74 GBV_ILN_90 GBV_ILN_95 GBV_ILN_100 GBV_ILN_101 GBV_ILN_105 GBV_ILN_110 GBV_ILN_150 GBV_ILN_151 GBV_ILN_224 GBV_ILN_370 GBV_ILN_602 GBV_ILN_702 GBV_ILN_2003 GBV_ILN_2004 GBV_ILN_2005 GBV_ILN_2011 GBV_ILN_2014 GBV_ILN_2015 GBV_ILN_2020 GBV_ILN_2021 GBV_ILN_2025 GBV_ILN_2027 GBV_ILN_2034 GBV_ILN_2038 GBV_ILN_2044 GBV_ILN_2048 GBV_ILN_2049 GBV_ILN_2050 GBV_ILN_2056 GBV_ILN_2059 GBV_ILN_2061 GBV_ILN_2064 GBV_ILN_2065 GBV_ILN_2068 GBV_ILN_2111 GBV_ILN_2112 GBV_ILN_2113 GBV_ILN_2118 GBV_ILN_2122 GBV_ILN_2129 GBV_ILN_2143 GBV_ILN_2147 GBV_ILN_2148 GBV_ILN_2152 GBV_ILN_2153 GBV_ILN_2190 GBV_ILN_2336 GBV_ILN_2507 GBV_ILN_2522 GBV_ILN_4035 GBV_ILN_4037 GBV_ILN_4112 GBV_ILN_4125 GBV_ILN_4126 GBV_ILN_4242 GBV_ILN_4251 GBV_ILN_4305 GBV_ILN_4313 GBV_ILN_4323 GBV_ILN_4324 GBV_ILN_4326 GBV_ILN_4333 GBV_ILN_4334 GBV_ILN_4335 GBV_ILN_4338 GBV_ILN_4393 43.13 Umwelttoxikologie 50.17 Sicherheitstechnik 58.53 Abfallwirtschaft AR 398 |
allfields_unstemmed |
10.1016/j.jhazmat.2020.122828 doi (DE-627)ELV004553411 (ELSEVIER)S0304-3894(20)30817-7 DE-627 ger DE-627 rda eng 530 DE-600 43.13 bkl 50.17 bkl 58.53 bkl Zhou, Yanqiu verfasserin aut Prenatal exposure to benzotraizoles and benzothiazoles in relation to fetal and birth size: A longitudinal study 2020 nicht spezifiziert zzz rdacontent Computermedien c rdamedia Online-Ressource cr rdacarrier The presence of benzotriazoles and benzothiazoles (BTs) in maternal urine and amniotic fluid indicated the widespread fetal exposure to the contaminants. We investigated the associations of prenatal BTs exposure with fetal and birth size and explored the window of susceptibility. Participants consisted of 856 mother-infant pairs drawn from a prospective birth cohort between 2014 and 2015 in Wuhan, China. Prenatal BTs exposure were measured in multiple urine samples collected across three trimesters. We observed positive associations between prenatal exposure to specific BTs (e.g., 1-H-benzotriazole, 1-hydroxy-benzotriazole and 2-amino-benzothiazole) and femur length (FL) and birth length z-scores among girls. In boys, a 2-fold increase of averaged concentration of urinary benzothiazole (BTH) was associated with decrement in FL (β = -0.068, p < 0.001) and birth length (β = -0.055, p = 0.005) z-scores. Further analysis indicated that the negative associations between urinary concentrations of BTH and birth length z-score among boys were observed at exposure measurement in 25–35 gestational weeks. This study reported the associations between prenatal exposure to BTs and fetal and birth size, suggests the associations maybe in a sex-specific manner and the window of exposure may influence susceptibility. These findings require replication in future research. Benzotriazole Benzothiazole Fetal and birth size Longitudinal Li, Ying verfasserin aut Xu, Shunqing verfasserin aut Liao, Jiaqiang verfasserin aut Zhang, Hongna verfasserin aut Li, Jiufeng verfasserin aut Hong, Yanjun verfasserin aut Xia, Wei verfasserin aut Cai, Zongwei verfasserin aut Enthalten in Journal of hazardous materials New York, NY [u.a.] : Science Direct, 1976 398 Online-Ressource (DE-627)302467904 (DE-600)1491302-1 (DE-576)259483893 1873-3336 nnns volume:398 GBV_USEFLAG_U SYSFLAG_U GBV_ELV SSG-OPC-GGO GBV_ILN_20 GBV_ILN_22 GBV_ILN_23 GBV_ILN_24 GBV_ILN_31 GBV_ILN_32 GBV_ILN_40 GBV_ILN_60 GBV_ILN_62 GBV_ILN_63 GBV_ILN_65 GBV_ILN_69 GBV_ILN_70 GBV_ILN_73 GBV_ILN_74 GBV_ILN_90 GBV_ILN_95 GBV_ILN_100 GBV_ILN_101 GBV_ILN_105 GBV_ILN_110 GBV_ILN_150 GBV_ILN_151 GBV_ILN_224 GBV_ILN_370 GBV_ILN_602 GBV_ILN_702 GBV_ILN_2003 GBV_ILN_2004 GBV_ILN_2005 GBV_ILN_2011 GBV_ILN_2014 GBV_ILN_2015 GBV_ILN_2020 GBV_ILN_2021 GBV_ILN_2025 GBV_ILN_2027 GBV_ILN_2034 GBV_ILN_2038 GBV_ILN_2044 GBV_ILN_2048 GBV_ILN_2049 GBV_ILN_2050 GBV_ILN_2056 GBV_ILN_2059 GBV_ILN_2061 GBV_ILN_2064 GBV_ILN_2065 GBV_ILN_2068 GBV_ILN_2111 GBV_ILN_2112 GBV_ILN_2113 GBV_ILN_2118 GBV_ILN_2122 GBV_ILN_2129 GBV_ILN_2143 GBV_ILN_2147 GBV_ILN_2148 GBV_ILN_2152 GBV_ILN_2153 GBV_ILN_2190 GBV_ILN_2336 GBV_ILN_2507 GBV_ILN_2522 GBV_ILN_4035 GBV_ILN_4037 GBV_ILN_4112 GBV_ILN_4125 GBV_ILN_4126 GBV_ILN_4242 GBV_ILN_4251 GBV_ILN_4305 GBV_ILN_4313 GBV_ILN_4323 GBV_ILN_4324 GBV_ILN_4326 GBV_ILN_4333 GBV_ILN_4334 GBV_ILN_4335 GBV_ILN_4338 GBV_ILN_4393 43.13 Umwelttoxikologie 50.17 Sicherheitstechnik 58.53 Abfallwirtschaft AR 398 |
allfieldsGer |
10.1016/j.jhazmat.2020.122828 doi (DE-627)ELV004553411 (ELSEVIER)S0304-3894(20)30817-7 DE-627 ger DE-627 rda eng 530 DE-600 43.13 bkl 50.17 bkl 58.53 bkl Zhou, Yanqiu verfasserin aut Prenatal exposure to benzotraizoles and benzothiazoles in relation to fetal and birth size: A longitudinal study 2020 nicht spezifiziert zzz rdacontent Computermedien c rdamedia Online-Ressource cr rdacarrier The presence of benzotriazoles and benzothiazoles (BTs) in maternal urine and amniotic fluid indicated the widespread fetal exposure to the contaminants. We investigated the associations of prenatal BTs exposure with fetal and birth size and explored the window of susceptibility. Participants consisted of 856 mother-infant pairs drawn from a prospective birth cohort between 2014 and 2015 in Wuhan, China. Prenatal BTs exposure were measured in multiple urine samples collected across three trimesters. We observed positive associations between prenatal exposure to specific BTs (e.g., 1-H-benzotriazole, 1-hydroxy-benzotriazole and 2-amino-benzothiazole) and femur length (FL) and birth length z-scores among girls. In boys, a 2-fold increase of averaged concentration of urinary benzothiazole (BTH) was associated with decrement in FL (β = -0.068, p < 0.001) and birth length (β = -0.055, p = 0.005) z-scores. Further analysis indicated that the negative associations between urinary concentrations of BTH and birth length z-score among boys were observed at exposure measurement in 25–35 gestational weeks. This study reported the associations between prenatal exposure to BTs and fetal and birth size, suggests the associations maybe in a sex-specific manner and the window of exposure may influence susceptibility. These findings require replication in future research. Benzotriazole Benzothiazole Fetal and birth size Longitudinal Li, Ying verfasserin aut Xu, Shunqing verfasserin aut Liao, Jiaqiang verfasserin aut Zhang, Hongna verfasserin aut Li, Jiufeng verfasserin aut Hong, Yanjun verfasserin aut Xia, Wei verfasserin aut Cai, Zongwei verfasserin aut Enthalten in Journal of hazardous materials New York, NY [u.a.] : Science Direct, 1976 398 Online-Ressource (DE-627)302467904 (DE-600)1491302-1 (DE-576)259483893 1873-3336 nnns volume:398 GBV_USEFLAG_U SYSFLAG_U GBV_ELV SSG-OPC-GGO GBV_ILN_20 GBV_ILN_22 GBV_ILN_23 GBV_ILN_24 GBV_ILN_31 GBV_ILN_32 GBV_ILN_40 GBV_ILN_60 GBV_ILN_62 GBV_ILN_63 GBV_ILN_65 GBV_ILN_69 GBV_ILN_70 GBV_ILN_73 GBV_ILN_74 GBV_ILN_90 GBV_ILN_95 GBV_ILN_100 GBV_ILN_101 GBV_ILN_105 GBV_ILN_110 GBV_ILN_150 GBV_ILN_151 GBV_ILN_224 GBV_ILN_370 GBV_ILN_602 GBV_ILN_702 GBV_ILN_2003 GBV_ILN_2004 GBV_ILN_2005 GBV_ILN_2011 GBV_ILN_2014 GBV_ILN_2015 GBV_ILN_2020 GBV_ILN_2021 GBV_ILN_2025 GBV_ILN_2027 GBV_ILN_2034 GBV_ILN_2038 GBV_ILN_2044 GBV_ILN_2048 GBV_ILN_2049 GBV_ILN_2050 GBV_ILN_2056 GBV_ILN_2059 GBV_ILN_2061 GBV_ILN_2064 GBV_ILN_2065 GBV_ILN_2068 GBV_ILN_2111 GBV_ILN_2112 GBV_ILN_2113 GBV_ILN_2118 GBV_ILN_2122 GBV_ILN_2129 GBV_ILN_2143 GBV_ILN_2147 GBV_ILN_2148 GBV_ILN_2152 GBV_ILN_2153 GBV_ILN_2190 GBV_ILN_2336 GBV_ILN_2507 GBV_ILN_2522 GBV_ILN_4035 GBV_ILN_4037 GBV_ILN_4112 GBV_ILN_4125 GBV_ILN_4126 GBV_ILN_4242 GBV_ILN_4251 GBV_ILN_4305 GBV_ILN_4313 GBV_ILN_4323 GBV_ILN_4324 GBV_ILN_4326 GBV_ILN_4333 GBV_ILN_4334 GBV_ILN_4335 GBV_ILN_4338 GBV_ILN_4393 43.13 Umwelttoxikologie 50.17 Sicherheitstechnik 58.53 Abfallwirtschaft AR 398 |
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10.1016/j.jhazmat.2020.122828 doi (DE-627)ELV004553411 (ELSEVIER)S0304-3894(20)30817-7 DE-627 ger DE-627 rda eng 530 DE-600 43.13 bkl 50.17 bkl 58.53 bkl Zhou, Yanqiu verfasserin aut Prenatal exposure to benzotraizoles and benzothiazoles in relation to fetal and birth size: A longitudinal study 2020 nicht spezifiziert zzz rdacontent Computermedien c rdamedia Online-Ressource cr rdacarrier The presence of benzotriazoles and benzothiazoles (BTs) in maternal urine and amniotic fluid indicated the widespread fetal exposure to the contaminants. We investigated the associations of prenatal BTs exposure with fetal and birth size and explored the window of susceptibility. Participants consisted of 856 mother-infant pairs drawn from a prospective birth cohort between 2014 and 2015 in Wuhan, China. Prenatal BTs exposure were measured in multiple urine samples collected across three trimesters. We observed positive associations between prenatal exposure to specific BTs (e.g., 1-H-benzotriazole, 1-hydroxy-benzotriazole and 2-amino-benzothiazole) and femur length (FL) and birth length z-scores among girls. In boys, a 2-fold increase of averaged concentration of urinary benzothiazole (BTH) was associated with decrement in FL (β = -0.068, p < 0.001) and birth length (β = -0.055, p = 0.005) z-scores. Further analysis indicated that the negative associations between urinary concentrations of BTH and birth length z-score among boys were observed at exposure measurement in 25–35 gestational weeks. This study reported the associations between prenatal exposure to BTs and fetal and birth size, suggests the associations maybe in a sex-specific manner and the window of exposure may influence susceptibility. These findings require replication in future research. Benzotriazole Benzothiazole Fetal and birth size Longitudinal Li, Ying verfasserin aut Xu, Shunqing verfasserin aut Liao, Jiaqiang verfasserin aut Zhang, Hongna verfasserin aut Li, Jiufeng verfasserin aut Hong, Yanjun verfasserin aut Xia, Wei verfasserin aut Cai, Zongwei verfasserin aut Enthalten in Journal of hazardous materials New York, NY [u.a.] : Science Direct, 1976 398 Online-Ressource (DE-627)302467904 (DE-600)1491302-1 (DE-576)259483893 1873-3336 nnns volume:398 GBV_USEFLAG_U SYSFLAG_U GBV_ELV SSG-OPC-GGO GBV_ILN_20 GBV_ILN_22 GBV_ILN_23 GBV_ILN_24 GBV_ILN_31 GBV_ILN_32 GBV_ILN_40 GBV_ILN_60 GBV_ILN_62 GBV_ILN_63 GBV_ILN_65 GBV_ILN_69 GBV_ILN_70 GBV_ILN_73 GBV_ILN_74 GBV_ILN_90 GBV_ILN_95 GBV_ILN_100 GBV_ILN_101 GBV_ILN_105 GBV_ILN_110 GBV_ILN_150 GBV_ILN_151 GBV_ILN_224 GBV_ILN_370 GBV_ILN_602 GBV_ILN_702 GBV_ILN_2003 GBV_ILN_2004 GBV_ILN_2005 GBV_ILN_2011 GBV_ILN_2014 GBV_ILN_2015 GBV_ILN_2020 GBV_ILN_2021 GBV_ILN_2025 GBV_ILN_2027 GBV_ILN_2034 GBV_ILN_2038 GBV_ILN_2044 GBV_ILN_2048 GBV_ILN_2049 GBV_ILN_2050 GBV_ILN_2056 GBV_ILN_2059 GBV_ILN_2061 GBV_ILN_2064 GBV_ILN_2065 GBV_ILN_2068 GBV_ILN_2111 GBV_ILN_2112 GBV_ILN_2113 GBV_ILN_2118 GBV_ILN_2122 GBV_ILN_2129 GBV_ILN_2143 GBV_ILN_2147 GBV_ILN_2148 GBV_ILN_2152 GBV_ILN_2153 GBV_ILN_2190 GBV_ILN_2336 GBV_ILN_2507 GBV_ILN_2522 GBV_ILN_4035 GBV_ILN_4037 GBV_ILN_4112 GBV_ILN_4125 GBV_ILN_4126 GBV_ILN_4242 GBV_ILN_4251 GBV_ILN_4305 GBV_ILN_4313 GBV_ILN_4323 GBV_ILN_4324 GBV_ILN_4326 GBV_ILN_4333 GBV_ILN_4334 GBV_ILN_4335 GBV_ILN_4338 GBV_ILN_4393 43.13 Umwelttoxikologie 50.17 Sicherheitstechnik 58.53 Abfallwirtschaft AR 398 |
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530 DE-600 43.13 bkl 50.17 bkl 58.53 bkl Prenatal exposure to benzotraizoles and benzothiazoles in relation to fetal and birth size: A longitudinal study Benzotriazole Benzothiazole Fetal and birth size Longitudinal |
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ddc 530 bkl 43.13 bkl 50.17 bkl 58.53 misc Benzotriazole misc Benzothiazole misc Fetal and birth size misc Longitudinal |
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ddc 530 bkl 43.13 bkl 50.17 bkl 58.53 misc Benzotriazole misc Benzothiazole misc Fetal and birth size misc Longitudinal |
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ddc 530 bkl 43.13 bkl 50.17 bkl 58.53 misc Benzotriazole misc Benzothiazole misc Fetal and birth size misc Longitudinal |
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Prenatal exposure to benzotraizoles and benzothiazoles in relation to fetal and birth size: A longitudinal study |
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Prenatal exposure to benzotraizoles and benzothiazoles in relation to fetal and birth size: A longitudinal study |
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Zhou, Yanqiu Li, Ying Xu, Shunqing Liao, Jiaqiang Zhang, Hongna Li, Jiufeng Hong, Yanjun Xia, Wei Cai, Zongwei |
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398 |
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10.1016/j.jhazmat.2020.122828 |
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prenatal exposure to benzotraizoles and benzothiazoles in relation to fetal and birth size: a longitudinal study |
title_auth |
Prenatal exposure to benzotraizoles and benzothiazoles in relation to fetal and birth size: A longitudinal study |
abstract |
The presence of benzotriazoles and benzothiazoles (BTs) in maternal urine and amniotic fluid indicated the widespread fetal exposure to the contaminants. We investigated the associations of prenatal BTs exposure with fetal and birth size and explored the window of susceptibility. Participants consisted of 856 mother-infant pairs drawn from a prospective birth cohort between 2014 and 2015 in Wuhan, China. Prenatal BTs exposure were measured in multiple urine samples collected across three trimesters. We observed positive associations between prenatal exposure to specific BTs (e.g., 1-H-benzotriazole, 1-hydroxy-benzotriazole and 2-amino-benzothiazole) and femur length (FL) and birth length z-scores among girls. In boys, a 2-fold increase of averaged concentration of urinary benzothiazole (BTH) was associated with decrement in FL (β = -0.068, p < 0.001) and birth length (β = -0.055, p = 0.005) z-scores. Further analysis indicated that the negative associations between urinary concentrations of BTH and birth length z-score among boys were observed at exposure measurement in 25–35 gestational weeks. This study reported the associations between prenatal exposure to BTs and fetal and birth size, suggests the associations maybe in a sex-specific manner and the window of exposure may influence susceptibility. These findings require replication in future research. |
abstractGer |
The presence of benzotriazoles and benzothiazoles (BTs) in maternal urine and amniotic fluid indicated the widespread fetal exposure to the contaminants. We investigated the associations of prenatal BTs exposure with fetal and birth size and explored the window of susceptibility. Participants consisted of 856 mother-infant pairs drawn from a prospective birth cohort between 2014 and 2015 in Wuhan, China. Prenatal BTs exposure were measured in multiple urine samples collected across three trimesters. We observed positive associations between prenatal exposure to specific BTs (e.g., 1-H-benzotriazole, 1-hydroxy-benzotriazole and 2-amino-benzothiazole) and femur length (FL) and birth length z-scores among girls. In boys, a 2-fold increase of averaged concentration of urinary benzothiazole (BTH) was associated with decrement in FL (β = -0.068, p < 0.001) and birth length (β = -0.055, p = 0.005) z-scores. Further analysis indicated that the negative associations between urinary concentrations of BTH and birth length z-score among boys were observed at exposure measurement in 25–35 gestational weeks. This study reported the associations between prenatal exposure to BTs and fetal and birth size, suggests the associations maybe in a sex-specific manner and the window of exposure may influence susceptibility. These findings require replication in future research. |
abstract_unstemmed |
The presence of benzotriazoles and benzothiazoles (BTs) in maternal urine and amniotic fluid indicated the widespread fetal exposure to the contaminants. We investigated the associations of prenatal BTs exposure with fetal and birth size and explored the window of susceptibility. Participants consisted of 856 mother-infant pairs drawn from a prospective birth cohort between 2014 and 2015 in Wuhan, China. Prenatal BTs exposure were measured in multiple urine samples collected across three trimesters. We observed positive associations between prenatal exposure to specific BTs (e.g., 1-H-benzotriazole, 1-hydroxy-benzotriazole and 2-amino-benzothiazole) and femur length (FL) and birth length z-scores among girls. In boys, a 2-fold increase of averaged concentration of urinary benzothiazole (BTH) was associated with decrement in FL (β = -0.068, p < 0.001) and birth length (β = -0.055, p = 0.005) z-scores. Further analysis indicated that the negative associations between urinary concentrations of BTH and birth length z-score among boys were observed at exposure measurement in 25–35 gestational weeks. This study reported the associations between prenatal exposure to BTs and fetal and birth size, suggests the associations maybe in a sex-specific manner and the window of exposure may influence susceptibility. These findings require replication in future research. |
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Prenatal exposure to benzotraizoles and benzothiazoles in relation to fetal and birth size: A longitudinal study |
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Li, Ying Xu, Shunqing Liao, Jiaqiang Zhang, Hongna Li, Jiufeng Hong, Yanjun Xia, Wei Cai, Zongwei |
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