Relation of Body Mass Index to Outcomes in Patients With Heart Failure Implanted With Left Ventricular Assist Devices
We aimed at characterizing the impact of low and high body mass index (BMI) on outcomes after left-ventricular assist device (LVAD) surgery and define the predictors of mortality in patients with abnormal BMI (low/high). This study was conducted in 19 centers from 2006 to 2016. Patients were divided...
Ausführliche Beschreibung
Gespeichert in:
| Format: |
E-Artikel |
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| Sprache: |
Englisch |
| Erschienen: |
2020 |
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| Übergeordnetes Werk: |
Enthalten in: The American journal of cardiology - Amsterdam [u.a.] : Elsevier, 1958, 133, Seite 81-88 |
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| Übergeordnetes Werk: |
volume:133 ; pages:81-88 |
| DOI / URN: |
10.1016/j.amjcard.2020.07.045 |
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ELV004716701 |
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| 245 | 1 | 0 | |a Relation of Body Mass Index to Outcomes in Patients With Heart Failure Implanted With Left Ventricular Assist Devices |
| 264 | 1 | |c 2020 | |
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| 520 | |a We aimed at characterizing the impact of low and high body mass index (BMI) on outcomes after left-ventricular assist device (LVAD) surgery and define the predictors of mortality in patients with abnormal BMI (low/high). This study was conducted in 19 centers from 2006 to 2016. Patients were divided based on their baseline BMI into 3 groups of BMI: low (BMI ≤18.5 kg/m²); normal (BMI = 18.5 to 24.99 kg/m²) and high (BMI ≥25 kg/m²) (including overweight (BMI = 25 to 29.99 kg/m²), and obesity (BMI ≥30 Kg/m²)). Among 652 patients, 29 (4.4%), 279 (42.8%) and 344 (52.8%) had a low-, normal-, and high BMI, respectively. Patients with high BMI were significantly more likely men, with more co-morbidities and more history of ventricular/supra-ventricular arrhythmias before LVAD implantation. Patients with abnormal BMI had significantly lower survival than those with normal BMI. Notably, those with low BMI experienced the worst survival whereas overweight or obese patients had similar survival. Four predictors of mortality for LVAD candidates with abnormal BMI were defined: total bilirubin ≥16 µmol/L before LVAD, hypertension, destination therapy, and cardiac surgery with LVAD. Depending on the number of predictor per patients, those with abnormal BMI may be divided in 3 groups of 1-year mortality risk, i.e., low (0 to 1 predictor: 29% and 31%), intermediate (2 to 3 predictors, 51% and 52%, respectively), and high (4 predictors: 83%). In conclusion, LVAD recipients with abnormal BMI experience lower survival, especially underweight patients. Four predictors of mortality have been identified for LVAD population with abnormal BMI, differentiating those a low-, intermediate-, and high risks of death. | ||
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10.1016/j.amjcard.2020.07.045 doi (DE-627)ELV004716701 (ELSEVIER)S0002-9149(20)30779-7 DE-627 ger DE-627 rda eng 610 DE-600 44.85 bkl Galand, Vincent verfasserin aut Relation of Body Mass Index to Outcomes in Patients With Heart Failure Implanted With Left Ventricular Assist Devices 2020 nicht spezifiziert zzz rdacontent Computermedien c rdamedia Online-Ressource cr rdacarrier We aimed at characterizing the impact of low and high body mass index (BMI) on outcomes after left-ventricular assist device (LVAD) surgery and define the predictors of mortality in patients with abnormal BMI (low/high). This study was conducted in 19 centers from 2006 to 2016. Patients were divided based on their baseline BMI into 3 groups of BMI: low (BMI ≤18.5 kg/m²); normal (BMI = 18.5 to 24.99 kg/m²) and high (BMI ≥25 kg/m²) (including overweight (BMI = 25 to 29.99 kg/m²), and obesity (BMI ≥30 Kg/m²)). Among 652 patients, 29 (4.4%), 279 (42.8%) and 344 (52.8%) had a low-, normal-, and high BMI, respectively. Patients with high BMI were significantly more likely men, with more co-morbidities and more history of ventricular/supra-ventricular arrhythmias before LVAD implantation. Patients with abnormal BMI had significantly lower survival than those with normal BMI. Notably, those with low BMI experienced the worst survival whereas overweight or obese patients had similar survival. Four predictors of mortality for LVAD candidates with abnormal BMI were defined: total bilirubin ≥16 µmol/L before LVAD, hypertension, destination therapy, and cardiac surgery with LVAD. Depending on the number of predictor per patients, those with abnormal BMI may be divided in 3 groups of 1-year mortality risk, i.e., low (0 to 1 predictor: 29% and 31%), intermediate (2 to 3 predictors, 51% and 52%, respectively), and high (4 predictors: 83%). In conclusion, LVAD recipients with abnormal BMI experience lower survival, especially underweight patients. Four predictors of mortality have been identified for LVAD population with abnormal BMI, differentiating those a low-, intermediate-, and high risks of death. Flécher, Erwan verfasserin aut Lelong, Bernard verfasserin aut Chabanne, Céline verfasserin aut Charton, Marion verfasserin (orcid)0000-0002-5020-0057 aut Goéminne, Céline verfasserin aut Vincentelli, André verfasserin aut Porterie, Jean verfasserin aut Delmas, Clément verfasserin aut Nubret, Karine verfasserin aut Pernot, Mathieu verfasserin aut Kindo, Michel verfasserin aut Hoang Minh, Tam verfasserin aut Gaudard, Philippe verfasserin (orcid)0000-0003-1192-8704 aut Rouvière, Philippe verfasserin aut Sénage, Thomas verfasserin aut Michel, Magali verfasserin aut Boignard, Aude verfasserin aut Chavanon, Olivier verfasserin aut Verdonk, Constance verfasserin aut Para, Marylou verfasserin aut Pelcé, Edeline verfasserin aut Gariboldi, Vlad verfasserin aut Pozzi, Matteo verfasserin (orcid)0000-0001-6550-0872 aut Obadia, Jean-François verfasserin aut Litzler, Pierre-Yves verfasserin aut Anselme, Frédéric verfasserin aut Blanchart, Katrien verfasserin aut Babatasi, Gerard verfasserin aut Garnier, Fabien verfasserin aut Bielefeld, Marie verfasserin aut Radu, Costin verfasserin aut Hamon, David verfasserin aut Bourguignon, Thierry verfasserin aut Genet, Thibaud verfasserin aut Eschalier, Romain verfasserin aut D'Ostrevy, Nicolas verfasserin aut Bories, Marie-Cécile verfasserin aut Varlet, Emilie verfasserin aut Vanhuyse, Fabrice verfasserin aut Sadoul, Nicolas verfasserin (orcid)0000-0001-5354-6312 aut Leclercq, Christophe verfasserin aut Martins, Raphaël P. verfasserin aut Enthalten in The American journal of cardiology Amsterdam [u.a.] : Elsevier, 1958 133, Seite 81-88 Online-Ressource (DE-627)320596249 (DE-600)2019595-3 (DE-576)10963392X 1879-1913 nnns volume:133 pages:81-88 GBV_USEFLAG_U SYSFLAG_U GBV_ELV SSG-OLC-PHA GBV_ILN_20 GBV_ILN_22 GBV_ILN_23 GBV_ILN_24 GBV_ILN_31 GBV_ILN_32 GBV_ILN_40 GBV_ILN_60 GBV_ILN_62 GBV_ILN_63 GBV_ILN_65 GBV_ILN_69 GBV_ILN_70 GBV_ILN_73 GBV_ILN_74 GBV_ILN_90 GBV_ILN_95 GBV_ILN_100 GBV_ILN_101 GBV_ILN_105 GBV_ILN_110 GBV_ILN_151 GBV_ILN_224 GBV_ILN_370 GBV_ILN_602 GBV_ILN_702 GBV_ILN_2003 GBV_ILN_2004 GBV_ILN_2005 GBV_ILN_2011 GBV_ILN_2014 GBV_ILN_2015 GBV_ILN_2020 GBV_ILN_2021 GBV_ILN_2025 GBV_ILN_2027 GBV_ILN_2034 GBV_ILN_2038 GBV_ILN_2044 GBV_ILN_2048 GBV_ILN_2049 GBV_ILN_2050 GBV_ILN_2056 GBV_ILN_2059 GBV_ILN_2061 GBV_ILN_2064 GBV_ILN_2065 GBV_ILN_2068 GBV_ILN_2111 GBV_ILN_2112 GBV_ILN_2113 GBV_ILN_2118 GBV_ILN_2122 GBV_ILN_2129 GBV_ILN_2143 GBV_ILN_2147 GBV_ILN_2148 GBV_ILN_2152 GBV_ILN_2153 GBV_ILN_2190 GBV_ILN_2336 GBV_ILN_2507 GBV_ILN_2522 GBV_ILN_4035 GBV_ILN_4037 GBV_ILN_4112 GBV_ILN_4125 GBV_ILN_4126 GBV_ILN_4242 GBV_ILN_4251 GBV_ILN_4305 GBV_ILN_4313 GBV_ILN_4323 GBV_ILN_4324 GBV_ILN_4325 GBV_ILN_4326 GBV_ILN_4333 GBV_ILN_4334 GBV_ILN_4335 GBV_ILN_4338 GBV_ILN_4393 44.85 Kardiologie Angiologie AR 133 81-88 |
| spelling |
10.1016/j.amjcard.2020.07.045 doi (DE-627)ELV004716701 (ELSEVIER)S0002-9149(20)30779-7 DE-627 ger DE-627 rda eng 610 DE-600 44.85 bkl Galand, Vincent verfasserin aut Relation of Body Mass Index to Outcomes in Patients With Heart Failure Implanted With Left Ventricular Assist Devices 2020 nicht spezifiziert zzz rdacontent Computermedien c rdamedia Online-Ressource cr rdacarrier We aimed at characterizing the impact of low and high body mass index (BMI) on outcomes after left-ventricular assist device (LVAD) surgery and define the predictors of mortality in patients with abnormal BMI (low/high). This study was conducted in 19 centers from 2006 to 2016. Patients were divided based on their baseline BMI into 3 groups of BMI: low (BMI ≤18.5 kg/m²); normal (BMI = 18.5 to 24.99 kg/m²) and high (BMI ≥25 kg/m²) (including overweight (BMI = 25 to 29.99 kg/m²), and obesity (BMI ≥30 Kg/m²)). Among 652 patients, 29 (4.4%), 279 (42.8%) and 344 (52.8%) had a low-, normal-, and high BMI, respectively. Patients with high BMI were significantly more likely men, with more co-morbidities and more history of ventricular/supra-ventricular arrhythmias before LVAD implantation. Patients with abnormal BMI had significantly lower survival than those with normal BMI. Notably, those with low BMI experienced the worst survival whereas overweight or obese patients had similar survival. Four predictors of mortality for LVAD candidates with abnormal BMI were defined: total bilirubin ≥16 µmol/L before LVAD, hypertension, destination therapy, and cardiac surgery with LVAD. Depending on the number of predictor per patients, those with abnormal BMI may be divided in 3 groups of 1-year mortality risk, i.e., low (0 to 1 predictor: 29% and 31%), intermediate (2 to 3 predictors, 51% and 52%, respectively), and high (4 predictors: 83%). In conclusion, LVAD recipients with abnormal BMI experience lower survival, especially underweight patients. Four predictors of mortality have been identified for LVAD population with abnormal BMI, differentiating those a low-, intermediate-, and high risks of death. Flécher, Erwan verfasserin aut Lelong, Bernard verfasserin aut Chabanne, Céline verfasserin aut Charton, Marion verfasserin (orcid)0000-0002-5020-0057 aut Goéminne, Céline verfasserin aut Vincentelli, André verfasserin aut Porterie, Jean verfasserin aut Delmas, Clément verfasserin aut Nubret, Karine verfasserin aut Pernot, Mathieu verfasserin aut Kindo, Michel verfasserin aut Hoang Minh, Tam verfasserin aut Gaudard, Philippe verfasserin (orcid)0000-0003-1192-8704 aut Rouvière, Philippe verfasserin aut Sénage, Thomas verfasserin aut Michel, Magali verfasserin aut Boignard, Aude verfasserin aut Chavanon, Olivier verfasserin aut Verdonk, Constance verfasserin aut Para, Marylou verfasserin aut Pelcé, Edeline verfasserin aut Gariboldi, Vlad verfasserin aut Pozzi, Matteo verfasserin (orcid)0000-0001-6550-0872 aut Obadia, Jean-François verfasserin aut Litzler, Pierre-Yves verfasserin aut Anselme, Frédéric verfasserin aut Blanchart, Katrien verfasserin aut Babatasi, Gerard verfasserin aut Garnier, Fabien verfasserin aut Bielefeld, Marie verfasserin aut Radu, Costin verfasserin aut Hamon, David verfasserin aut Bourguignon, Thierry verfasserin aut Genet, Thibaud verfasserin aut Eschalier, Romain verfasserin aut D'Ostrevy, Nicolas verfasserin aut Bories, Marie-Cécile verfasserin aut Varlet, Emilie verfasserin aut Vanhuyse, Fabrice verfasserin aut Sadoul, Nicolas verfasserin (orcid)0000-0001-5354-6312 aut Leclercq, Christophe verfasserin aut Martins, Raphaël P. verfasserin aut Enthalten in The American journal of cardiology Amsterdam [u.a.] : Elsevier, 1958 133, Seite 81-88 Online-Ressource (DE-627)320596249 (DE-600)2019595-3 (DE-576)10963392X 1879-1913 nnns volume:133 pages:81-88 GBV_USEFLAG_U SYSFLAG_U GBV_ELV SSG-OLC-PHA GBV_ILN_20 GBV_ILN_22 GBV_ILN_23 GBV_ILN_24 GBV_ILN_31 GBV_ILN_32 GBV_ILN_40 GBV_ILN_60 GBV_ILN_62 GBV_ILN_63 GBV_ILN_65 GBV_ILN_69 GBV_ILN_70 GBV_ILN_73 GBV_ILN_74 GBV_ILN_90 GBV_ILN_95 GBV_ILN_100 GBV_ILN_101 GBV_ILN_105 GBV_ILN_110 GBV_ILN_151 GBV_ILN_224 GBV_ILN_370 GBV_ILN_602 GBV_ILN_702 GBV_ILN_2003 GBV_ILN_2004 GBV_ILN_2005 GBV_ILN_2011 GBV_ILN_2014 GBV_ILN_2015 GBV_ILN_2020 GBV_ILN_2021 GBV_ILN_2025 GBV_ILN_2027 GBV_ILN_2034 GBV_ILN_2038 GBV_ILN_2044 GBV_ILN_2048 GBV_ILN_2049 GBV_ILN_2050 GBV_ILN_2056 GBV_ILN_2059 GBV_ILN_2061 GBV_ILN_2064 GBV_ILN_2065 GBV_ILN_2068 GBV_ILN_2111 GBV_ILN_2112 GBV_ILN_2113 GBV_ILN_2118 GBV_ILN_2122 GBV_ILN_2129 GBV_ILN_2143 GBV_ILN_2147 GBV_ILN_2148 GBV_ILN_2152 GBV_ILN_2153 GBV_ILN_2190 GBV_ILN_2336 GBV_ILN_2507 GBV_ILN_2522 GBV_ILN_4035 GBV_ILN_4037 GBV_ILN_4112 GBV_ILN_4125 GBV_ILN_4126 GBV_ILN_4242 GBV_ILN_4251 GBV_ILN_4305 GBV_ILN_4313 GBV_ILN_4323 GBV_ILN_4324 GBV_ILN_4325 GBV_ILN_4326 GBV_ILN_4333 GBV_ILN_4334 GBV_ILN_4335 GBV_ILN_4338 GBV_ILN_4393 44.85 Kardiologie Angiologie AR 133 81-88 |
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10.1016/j.amjcard.2020.07.045 doi (DE-627)ELV004716701 (ELSEVIER)S0002-9149(20)30779-7 DE-627 ger DE-627 rda eng 610 DE-600 44.85 bkl Galand, Vincent verfasserin aut Relation of Body Mass Index to Outcomes in Patients With Heart Failure Implanted With Left Ventricular Assist Devices 2020 nicht spezifiziert zzz rdacontent Computermedien c rdamedia Online-Ressource cr rdacarrier We aimed at characterizing the impact of low and high body mass index (BMI) on outcomes after left-ventricular assist device (LVAD) surgery and define the predictors of mortality in patients with abnormal BMI (low/high). This study was conducted in 19 centers from 2006 to 2016. Patients were divided based on their baseline BMI into 3 groups of BMI: low (BMI ≤18.5 kg/m²); normal (BMI = 18.5 to 24.99 kg/m²) and high (BMI ≥25 kg/m²) (including overweight (BMI = 25 to 29.99 kg/m²), and obesity (BMI ≥30 Kg/m²)). Among 652 patients, 29 (4.4%), 279 (42.8%) and 344 (52.8%) had a low-, normal-, and high BMI, respectively. Patients with high BMI were significantly more likely men, with more co-morbidities and more history of ventricular/supra-ventricular arrhythmias before LVAD implantation. Patients with abnormal BMI had significantly lower survival than those with normal BMI. Notably, those with low BMI experienced the worst survival whereas overweight or obese patients had similar survival. Four predictors of mortality for LVAD candidates with abnormal BMI were defined: total bilirubin ≥16 µmol/L before LVAD, hypertension, destination therapy, and cardiac surgery with LVAD. Depending on the number of predictor per patients, those with abnormal BMI may be divided in 3 groups of 1-year mortality risk, i.e., low (0 to 1 predictor: 29% and 31%), intermediate (2 to 3 predictors, 51% and 52%, respectively), and high (4 predictors: 83%). In conclusion, LVAD recipients with abnormal BMI experience lower survival, especially underweight patients. Four predictors of mortality have been identified for LVAD population with abnormal BMI, differentiating those a low-, intermediate-, and high risks of death. Flécher, Erwan verfasserin aut Lelong, Bernard verfasserin aut Chabanne, Céline verfasserin aut Charton, Marion verfasserin (orcid)0000-0002-5020-0057 aut Goéminne, Céline verfasserin aut Vincentelli, André verfasserin aut Porterie, Jean verfasserin aut Delmas, Clément verfasserin aut Nubret, Karine verfasserin aut Pernot, Mathieu verfasserin aut Kindo, Michel verfasserin aut Hoang Minh, Tam verfasserin aut Gaudard, Philippe verfasserin (orcid)0000-0003-1192-8704 aut Rouvière, Philippe verfasserin aut Sénage, Thomas verfasserin aut Michel, Magali verfasserin aut Boignard, Aude verfasserin aut Chavanon, Olivier verfasserin aut Verdonk, Constance verfasserin aut Para, Marylou verfasserin aut Pelcé, Edeline verfasserin aut Gariboldi, Vlad verfasserin aut Pozzi, Matteo verfasserin (orcid)0000-0001-6550-0872 aut Obadia, Jean-François verfasserin aut Litzler, Pierre-Yves verfasserin aut Anselme, Frédéric verfasserin aut Blanchart, Katrien verfasserin aut Babatasi, Gerard verfasserin aut Garnier, Fabien verfasserin aut Bielefeld, Marie verfasserin aut Radu, Costin verfasserin aut Hamon, David verfasserin aut Bourguignon, Thierry verfasserin aut Genet, Thibaud verfasserin aut Eschalier, Romain verfasserin aut D'Ostrevy, Nicolas verfasserin aut Bories, Marie-Cécile verfasserin aut Varlet, Emilie verfasserin aut Vanhuyse, Fabrice verfasserin aut Sadoul, Nicolas verfasserin (orcid)0000-0001-5354-6312 aut Leclercq, Christophe verfasserin aut Martins, Raphaël P. verfasserin aut Enthalten in The American journal of cardiology Amsterdam [u.a.] : Elsevier, 1958 133, Seite 81-88 Online-Ressource (DE-627)320596249 (DE-600)2019595-3 (DE-576)10963392X 1879-1913 nnns volume:133 pages:81-88 GBV_USEFLAG_U SYSFLAG_U GBV_ELV SSG-OLC-PHA GBV_ILN_20 GBV_ILN_22 GBV_ILN_23 GBV_ILN_24 GBV_ILN_31 GBV_ILN_32 GBV_ILN_40 GBV_ILN_60 GBV_ILN_62 GBV_ILN_63 GBV_ILN_65 GBV_ILN_69 GBV_ILN_70 GBV_ILN_73 GBV_ILN_74 GBV_ILN_90 GBV_ILN_95 GBV_ILN_100 GBV_ILN_101 GBV_ILN_105 GBV_ILN_110 GBV_ILN_151 GBV_ILN_224 GBV_ILN_370 GBV_ILN_602 GBV_ILN_702 GBV_ILN_2003 GBV_ILN_2004 GBV_ILN_2005 GBV_ILN_2011 GBV_ILN_2014 GBV_ILN_2015 GBV_ILN_2020 GBV_ILN_2021 GBV_ILN_2025 GBV_ILN_2027 GBV_ILN_2034 GBV_ILN_2038 GBV_ILN_2044 GBV_ILN_2048 GBV_ILN_2049 GBV_ILN_2050 GBV_ILN_2056 GBV_ILN_2059 GBV_ILN_2061 GBV_ILN_2064 GBV_ILN_2065 GBV_ILN_2068 GBV_ILN_2111 GBV_ILN_2112 GBV_ILN_2113 GBV_ILN_2118 GBV_ILN_2122 GBV_ILN_2129 GBV_ILN_2143 GBV_ILN_2147 GBV_ILN_2148 GBV_ILN_2152 GBV_ILN_2153 GBV_ILN_2190 GBV_ILN_2336 GBV_ILN_2507 GBV_ILN_2522 GBV_ILN_4035 GBV_ILN_4037 GBV_ILN_4112 GBV_ILN_4125 GBV_ILN_4126 GBV_ILN_4242 GBV_ILN_4251 GBV_ILN_4305 GBV_ILN_4313 GBV_ILN_4323 GBV_ILN_4324 GBV_ILN_4325 GBV_ILN_4326 GBV_ILN_4333 GBV_ILN_4334 GBV_ILN_4335 GBV_ILN_4338 GBV_ILN_4393 44.85 Kardiologie Angiologie AR 133 81-88 |
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10.1016/j.amjcard.2020.07.045 doi (DE-627)ELV004716701 (ELSEVIER)S0002-9149(20)30779-7 DE-627 ger DE-627 rda eng 610 DE-600 44.85 bkl Galand, Vincent verfasserin aut Relation of Body Mass Index to Outcomes in Patients With Heart Failure Implanted With Left Ventricular Assist Devices 2020 nicht spezifiziert zzz rdacontent Computermedien c rdamedia Online-Ressource cr rdacarrier We aimed at characterizing the impact of low and high body mass index (BMI) on outcomes after left-ventricular assist device (LVAD) surgery and define the predictors of mortality in patients with abnormal BMI (low/high). This study was conducted in 19 centers from 2006 to 2016. Patients were divided based on their baseline BMI into 3 groups of BMI: low (BMI ≤18.5 kg/m²); normal (BMI = 18.5 to 24.99 kg/m²) and high (BMI ≥25 kg/m²) (including overweight (BMI = 25 to 29.99 kg/m²), and obesity (BMI ≥30 Kg/m²)). Among 652 patients, 29 (4.4%), 279 (42.8%) and 344 (52.8%) had a low-, normal-, and high BMI, respectively. Patients with high BMI were significantly more likely men, with more co-morbidities and more history of ventricular/supra-ventricular arrhythmias before LVAD implantation. Patients with abnormal BMI had significantly lower survival than those with normal BMI. Notably, those with low BMI experienced the worst survival whereas overweight or obese patients had similar survival. Four predictors of mortality for LVAD candidates with abnormal BMI were defined: total bilirubin ≥16 µmol/L before LVAD, hypertension, destination therapy, and cardiac surgery with LVAD. Depending on the number of predictor per patients, those with abnormal BMI may be divided in 3 groups of 1-year mortality risk, i.e., low (0 to 1 predictor: 29% and 31%), intermediate (2 to 3 predictors, 51% and 52%, respectively), and high (4 predictors: 83%). In conclusion, LVAD recipients with abnormal BMI experience lower survival, especially underweight patients. Four predictors of mortality have been identified for LVAD population with abnormal BMI, differentiating those a low-, intermediate-, and high risks of death. Flécher, Erwan verfasserin aut Lelong, Bernard verfasserin aut Chabanne, Céline verfasserin aut Charton, Marion verfasserin (orcid)0000-0002-5020-0057 aut Goéminne, Céline verfasserin aut Vincentelli, André verfasserin aut Porterie, Jean verfasserin aut Delmas, Clément verfasserin aut Nubret, Karine verfasserin aut Pernot, Mathieu verfasserin aut Kindo, Michel verfasserin aut Hoang Minh, Tam verfasserin aut Gaudard, Philippe verfasserin (orcid)0000-0003-1192-8704 aut Rouvière, Philippe verfasserin aut Sénage, Thomas verfasserin aut Michel, Magali verfasserin aut Boignard, Aude verfasserin aut Chavanon, Olivier verfasserin aut Verdonk, Constance verfasserin aut Para, Marylou verfasserin aut Pelcé, Edeline verfasserin aut Gariboldi, Vlad verfasserin aut Pozzi, Matteo verfasserin (orcid)0000-0001-6550-0872 aut Obadia, Jean-François verfasserin aut Litzler, Pierre-Yves verfasserin aut Anselme, Frédéric verfasserin aut Blanchart, Katrien verfasserin aut Babatasi, Gerard verfasserin aut Garnier, Fabien verfasserin aut Bielefeld, Marie verfasserin aut Radu, Costin verfasserin aut Hamon, David verfasserin aut Bourguignon, Thierry verfasserin aut Genet, Thibaud verfasserin aut Eschalier, Romain verfasserin aut D'Ostrevy, Nicolas verfasserin aut Bories, Marie-Cécile verfasserin aut Varlet, Emilie verfasserin aut Vanhuyse, Fabrice verfasserin aut Sadoul, Nicolas verfasserin (orcid)0000-0001-5354-6312 aut Leclercq, Christophe verfasserin aut Martins, Raphaël P. verfasserin aut Enthalten in The American journal of cardiology Amsterdam [u.a.] : Elsevier, 1958 133, Seite 81-88 Online-Ressource (DE-627)320596249 (DE-600)2019595-3 (DE-576)10963392X 1879-1913 nnns volume:133 pages:81-88 GBV_USEFLAG_U SYSFLAG_U GBV_ELV SSG-OLC-PHA GBV_ILN_20 GBV_ILN_22 GBV_ILN_23 GBV_ILN_24 GBV_ILN_31 GBV_ILN_32 GBV_ILN_40 GBV_ILN_60 GBV_ILN_62 GBV_ILN_63 GBV_ILN_65 GBV_ILN_69 GBV_ILN_70 GBV_ILN_73 GBV_ILN_74 GBV_ILN_90 GBV_ILN_95 GBV_ILN_100 GBV_ILN_101 GBV_ILN_105 GBV_ILN_110 GBV_ILN_151 GBV_ILN_224 GBV_ILN_370 GBV_ILN_602 GBV_ILN_702 GBV_ILN_2003 GBV_ILN_2004 GBV_ILN_2005 GBV_ILN_2011 GBV_ILN_2014 GBV_ILN_2015 GBV_ILN_2020 GBV_ILN_2021 GBV_ILN_2025 GBV_ILN_2027 GBV_ILN_2034 GBV_ILN_2038 GBV_ILN_2044 GBV_ILN_2048 GBV_ILN_2049 GBV_ILN_2050 GBV_ILN_2056 GBV_ILN_2059 GBV_ILN_2061 GBV_ILN_2064 GBV_ILN_2065 GBV_ILN_2068 GBV_ILN_2111 GBV_ILN_2112 GBV_ILN_2113 GBV_ILN_2118 GBV_ILN_2122 GBV_ILN_2129 GBV_ILN_2143 GBV_ILN_2147 GBV_ILN_2148 GBV_ILN_2152 GBV_ILN_2153 GBV_ILN_2190 GBV_ILN_2336 GBV_ILN_2507 GBV_ILN_2522 GBV_ILN_4035 GBV_ILN_4037 GBV_ILN_4112 GBV_ILN_4125 GBV_ILN_4126 GBV_ILN_4242 GBV_ILN_4251 GBV_ILN_4305 GBV_ILN_4313 GBV_ILN_4323 GBV_ILN_4324 GBV_ILN_4325 GBV_ILN_4326 GBV_ILN_4333 GBV_ILN_4334 GBV_ILN_4335 GBV_ILN_4338 GBV_ILN_4393 44.85 Kardiologie Angiologie AR 133 81-88 |
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10.1016/j.amjcard.2020.07.045 doi (DE-627)ELV004716701 (ELSEVIER)S0002-9149(20)30779-7 DE-627 ger DE-627 rda eng 610 DE-600 44.85 bkl Galand, Vincent verfasserin aut Relation of Body Mass Index to Outcomes in Patients With Heart Failure Implanted With Left Ventricular Assist Devices 2020 nicht spezifiziert zzz rdacontent Computermedien c rdamedia Online-Ressource cr rdacarrier We aimed at characterizing the impact of low and high body mass index (BMI) on outcomes after left-ventricular assist device (LVAD) surgery and define the predictors of mortality in patients with abnormal BMI (low/high). This study was conducted in 19 centers from 2006 to 2016. Patients were divided based on their baseline BMI into 3 groups of BMI: low (BMI ≤18.5 kg/m²); normal (BMI = 18.5 to 24.99 kg/m²) and high (BMI ≥25 kg/m²) (including overweight (BMI = 25 to 29.99 kg/m²), and obesity (BMI ≥30 Kg/m²)). Among 652 patients, 29 (4.4%), 279 (42.8%) and 344 (52.8%) had a low-, normal-, and high BMI, respectively. Patients with high BMI were significantly more likely men, with more co-morbidities and more history of ventricular/supra-ventricular arrhythmias before LVAD implantation. Patients with abnormal BMI had significantly lower survival than those with normal BMI. Notably, those with low BMI experienced the worst survival whereas overweight or obese patients had similar survival. Four predictors of mortality for LVAD candidates with abnormal BMI were defined: total bilirubin ≥16 µmol/L before LVAD, hypertension, destination therapy, and cardiac surgery with LVAD. Depending on the number of predictor per patients, those with abnormal BMI may be divided in 3 groups of 1-year mortality risk, i.e., low (0 to 1 predictor: 29% and 31%), intermediate (2 to 3 predictors, 51% and 52%, respectively), and high (4 predictors: 83%). In conclusion, LVAD recipients with abnormal BMI experience lower survival, especially underweight patients. Four predictors of mortality have been identified for LVAD population with abnormal BMI, differentiating those a low-, intermediate-, and high risks of death. Flécher, Erwan verfasserin aut Lelong, Bernard verfasserin aut Chabanne, Céline verfasserin aut Charton, Marion verfasserin (orcid)0000-0002-5020-0057 aut Goéminne, Céline verfasserin aut Vincentelli, André verfasserin aut Porterie, Jean verfasserin aut Delmas, Clément verfasserin aut Nubret, Karine verfasserin aut Pernot, Mathieu verfasserin aut Kindo, Michel verfasserin aut Hoang Minh, Tam verfasserin aut Gaudard, Philippe verfasserin (orcid)0000-0003-1192-8704 aut Rouvière, Philippe verfasserin aut Sénage, Thomas verfasserin aut Michel, Magali verfasserin aut Boignard, Aude verfasserin aut Chavanon, Olivier verfasserin aut Verdonk, Constance verfasserin aut Para, Marylou verfasserin aut Pelcé, Edeline verfasserin aut Gariboldi, Vlad verfasserin aut Pozzi, Matteo verfasserin (orcid)0000-0001-6550-0872 aut Obadia, Jean-François verfasserin aut Litzler, Pierre-Yves verfasserin aut Anselme, Frédéric verfasserin aut Blanchart, Katrien verfasserin aut Babatasi, Gerard verfasserin aut Garnier, Fabien verfasserin aut Bielefeld, Marie verfasserin aut Radu, Costin verfasserin aut Hamon, David verfasserin aut Bourguignon, Thierry verfasserin aut Genet, Thibaud verfasserin aut Eschalier, Romain verfasserin aut D'Ostrevy, Nicolas verfasserin aut Bories, Marie-Cécile verfasserin aut Varlet, Emilie verfasserin aut Vanhuyse, Fabrice verfasserin aut Sadoul, Nicolas verfasserin (orcid)0000-0001-5354-6312 aut Leclercq, Christophe verfasserin aut Martins, Raphaël P. verfasserin aut Enthalten in The American journal of cardiology Amsterdam [u.a.] : Elsevier, 1958 133, Seite 81-88 Online-Ressource (DE-627)320596249 (DE-600)2019595-3 (DE-576)10963392X 1879-1913 nnns volume:133 pages:81-88 GBV_USEFLAG_U SYSFLAG_U GBV_ELV SSG-OLC-PHA GBV_ILN_20 GBV_ILN_22 GBV_ILN_23 GBV_ILN_24 GBV_ILN_31 GBV_ILN_32 GBV_ILN_40 GBV_ILN_60 GBV_ILN_62 GBV_ILN_63 GBV_ILN_65 GBV_ILN_69 GBV_ILN_70 GBV_ILN_73 GBV_ILN_74 GBV_ILN_90 GBV_ILN_95 GBV_ILN_100 GBV_ILN_101 GBV_ILN_105 GBV_ILN_110 GBV_ILN_151 GBV_ILN_224 GBV_ILN_370 GBV_ILN_602 GBV_ILN_702 GBV_ILN_2003 GBV_ILN_2004 GBV_ILN_2005 GBV_ILN_2011 GBV_ILN_2014 GBV_ILN_2015 GBV_ILN_2020 GBV_ILN_2021 GBV_ILN_2025 GBV_ILN_2027 GBV_ILN_2034 GBV_ILN_2038 GBV_ILN_2044 GBV_ILN_2048 GBV_ILN_2049 GBV_ILN_2050 GBV_ILN_2056 GBV_ILN_2059 GBV_ILN_2061 GBV_ILN_2064 GBV_ILN_2065 GBV_ILN_2068 GBV_ILN_2111 GBV_ILN_2112 GBV_ILN_2113 GBV_ILN_2118 GBV_ILN_2122 GBV_ILN_2129 GBV_ILN_2143 GBV_ILN_2147 GBV_ILN_2148 GBV_ILN_2152 GBV_ILN_2153 GBV_ILN_2190 GBV_ILN_2336 GBV_ILN_2507 GBV_ILN_2522 GBV_ILN_4035 GBV_ILN_4037 GBV_ILN_4112 GBV_ILN_4125 GBV_ILN_4126 GBV_ILN_4242 GBV_ILN_4251 GBV_ILN_4305 GBV_ILN_4313 GBV_ILN_4323 GBV_ILN_4324 GBV_ILN_4325 GBV_ILN_4326 GBV_ILN_4333 GBV_ILN_4334 GBV_ILN_4335 GBV_ILN_4338 GBV_ILN_4393 44.85 Kardiologie Angiologie AR 133 81-88 |
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Enthalten in The American journal of cardiology 133, Seite 81-88 volume:133 pages:81-88 |
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Galand, Vincent @@aut@@ Flécher, Erwan @@aut@@ Lelong, Bernard @@aut@@ Chabanne, Céline @@aut@@ Charton, Marion @@aut@@ Goéminne, Céline @@aut@@ Vincentelli, André @@aut@@ Porterie, Jean @@aut@@ Delmas, Clément @@aut@@ Nubret, Karine @@aut@@ Pernot, Mathieu @@aut@@ Kindo, Michel @@aut@@ Hoang Minh, Tam @@aut@@ Gaudard, Philippe @@aut@@ Rouvière, Philippe @@aut@@ Sénage, Thomas @@aut@@ Michel, Magali @@aut@@ Boignard, Aude @@aut@@ Chavanon, Olivier @@aut@@ Verdonk, Constance @@aut@@ Para, Marylou @@aut@@ Pelcé, Edeline @@aut@@ Gariboldi, Vlad @@aut@@ Pozzi, Matteo @@aut@@ Obadia, Jean-François @@aut@@ Litzler, Pierre-Yves @@aut@@ Anselme, Frédéric @@aut@@ Blanchart, Katrien @@aut@@ Babatasi, Gerard @@aut@@ Garnier, Fabien @@aut@@ Bielefeld, Marie @@aut@@ Radu, Costin @@aut@@ Hamon, David @@aut@@ Bourguignon, Thierry @@aut@@ Genet, Thibaud @@aut@@ Eschalier, Romain @@aut@@ D'Ostrevy, Nicolas @@aut@@ Bories, Marie-Cécile @@aut@@ Varlet, Emilie @@aut@@ Vanhuyse, Fabrice @@aut@@ Sadoul, Nicolas @@aut@@ Leclercq, Christophe @@aut@@ Martins, Raphaël P. @@aut@@ |
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This study was conducted in 19 centers from 2006 to 2016. Patients were divided based on their baseline BMI into 3 groups of BMI: low (BMI ≤18.5 kg/m²); normal (BMI = 18.5 to 24.99 kg/m²) and high (BMI ≥25 kg/m²) (including overweight (BMI = 25 to 29.99 kg/m²), and obesity (BMI ≥30 Kg/m²)). Among 652 patients, 29 (4.4%), 279 (42.8%) and 344 (52.8%) had a low-, normal-, and high BMI, respectively. Patients with high BMI were significantly more likely men, with more co-morbidities and more history of ventricular/supra-ventricular arrhythmias before LVAD implantation. Patients with abnormal BMI had significantly lower survival than those with normal BMI. Notably, those with low BMI experienced the worst survival whereas overweight or obese patients had similar survival. Four predictors of mortality for LVAD candidates with abnormal BMI were defined: total bilirubin ≥16 µmol/L before LVAD, hypertension, destination therapy, and cardiac surgery with LVAD. 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Galand, Vincent |
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Galand, Vincent ddc 610 bkl 44.85 Relation of Body Mass Index to Outcomes in Patients With Heart Failure Implanted With Left Ventricular Assist Devices |
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610 DE-600 44.85 bkl Relation of Body Mass Index to Outcomes in Patients With Heart Failure Implanted With Left Ventricular Assist Devices |
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Galand, Vincent Flécher, Erwan Lelong, Bernard Chabanne, Céline Charton, Marion Goéminne, Céline Vincentelli, André Porterie, Jean Delmas, Clément Nubret, Karine Pernot, Mathieu Kindo, Michel Hoang Minh, Tam Gaudard, Philippe Rouvière, Philippe Sénage, Thomas Michel, Magali Boignard, Aude Chavanon, Olivier Verdonk, Constance Para, Marylou Pelcé, Edeline Gariboldi, Vlad Pozzi, Matteo Obadia, Jean-François Litzler, Pierre-Yves Anselme, Frédéric Blanchart, Katrien Babatasi, Gerard Garnier, Fabien Bielefeld, Marie Radu, Costin Hamon, David Bourguignon, Thierry Genet, Thibaud Eschalier, Romain D'Ostrevy, Nicolas Bories, Marie-Cécile Varlet, Emilie Vanhuyse, Fabrice Sadoul, Nicolas Leclercq, Christophe Martins, Raphaël P. |
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relation of body mass index to outcomes in patients with heart failure implanted with left ventricular assist devices |
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Relation of Body Mass Index to Outcomes in Patients With Heart Failure Implanted With Left Ventricular Assist Devices |
| abstract |
We aimed at characterizing the impact of low and high body mass index (BMI) on outcomes after left-ventricular assist device (LVAD) surgery and define the predictors of mortality in patients with abnormal BMI (low/high). This study was conducted in 19 centers from 2006 to 2016. Patients were divided based on their baseline BMI into 3 groups of BMI: low (BMI ≤18.5 kg/m²); normal (BMI = 18.5 to 24.99 kg/m²) and high (BMI ≥25 kg/m²) (including overweight (BMI = 25 to 29.99 kg/m²), and obesity (BMI ≥30 Kg/m²)). Among 652 patients, 29 (4.4%), 279 (42.8%) and 344 (52.8%) had a low-, normal-, and high BMI, respectively. Patients with high BMI were significantly more likely men, with more co-morbidities and more history of ventricular/supra-ventricular arrhythmias before LVAD implantation. Patients with abnormal BMI had significantly lower survival than those with normal BMI. Notably, those with low BMI experienced the worst survival whereas overweight or obese patients had similar survival. Four predictors of mortality for LVAD candidates with abnormal BMI were defined: total bilirubin ≥16 µmol/L before LVAD, hypertension, destination therapy, and cardiac surgery with LVAD. Depending on the number of predictor per patients, those with abnormal BMI may be divided in 3 groups of 1-year mortality risk, i.e., low (0 to 1 predictor: 29% and 31%), intermediate (2 to 3 predictors, 51% and 52%, respectively), and high (4 predictors: 83%). In conclusion, LVAD recipients with abnormal BMI experience lower survival, especially underweight patients. Four predictors of mortality have been identified for LVAD population with abnormal BMI, differentiating those a low-, intermediate-, and high risks of death. |
| abstractGer |
We aimed at characterizing the impact of low and high body mass index (BMI) on outcomes after left-ventricular assist device (LVAD) surgery and define the predictors of mortality in patients with abnormal BMI (low/high). This study was conducted in 19 centers from 2006 to 2016. Patients were divided based on their baseline BMI into 3 groups of BMI: low (BMI ≤18.5 kg/m²); normal (BMI = 18.5 to 24.99 kg/m²) and high (BMI ≥25 kg/m²) (including overweight (BMI = 25 to 29.99 kg/m²), and obesity (BMI ≥30 Kg/m²)). Among 652 patients, 29 (4.4%), 279 (42.8%) and 344 (52.8%) had a low-, normal-, and high BMI, respectively. Patients with high BMI were significantly more likely men, with more co-morbidities and more history of ventricular/supra-ventricular arrhythmias before LVAD implantation. Patients with abnormal BMI had significantly lower survival than those with normal BMI. Notably, those with low BMI experienced the worst survival whereas overweight or obese patients had similar survival. Four predictors of mortality for LVAD candidates with abnormal BMI were defined: total bilirubin ≥16 µmol/L before LVAD, hypertension, destination therapy, and cardiac surgery with LVAD. Depending on the number of predictor per patients, those with abnormal BMI may be divided in 3 groups of 1-year mortality risk, i.e., low (0 to 1 predictor: 29% and 31%), intermediate (2 to 3 predictors, 51% and 52%, respectively), and high (4 predictors: 83%). In conclusion, LVAD recipients with abnormal BMI experience lower survival, especially underweight patients. Four predictors of mortality have been identified for LVAD population with abnormal BMI, differentiating those a low-, intermediate-, and high risks of death. |
| abstract_unstemmed |
We aimed at characterizing the impact of low and high body mass index (BMI) on outcomes after left-ventricular assist device (LVAD) surgery and define the predictors of mortality in patients with abnormal BMI (low/high). This study was conducted in 19 centers from 2006 to 2016. Patients were divided based on their baseline BMI into 3 groups of BMI: low (BMI ≤18.5 kg/m²); normal (BMI = 18.5 to 24.99 kg/m²) and high (BMI ≥25 kg/m²) (including overweight (BMI = 25 to 29.99 kg/m²), and obesity (BMI ≥30 Kg/m²)). Among 652 patients, 29 (4.4%), 279 (42.8%) and 344 (52.8%) had a low-, normal-, and high BMI, respectively. Patients with high BMI were significantly more likely men, with more co-morbidities and more history of ventricular/supra-ventricular arrhythmias before LVAD implantation. Patients with abnormal BMI had significantly lower survival than those with normal BMI. Notably, those with low BMI experienced the worst survival whereas overweight or obese patients had similar survival. Four predictors of mortality for LVAD candidates with abnormal BMI were defined: total bilirubin ≥16 µmol/L before LVAD, hypertension, destination therapy, and cardiac surgery with LVAD. Depending on the number of predictor per patients, those with abnormal BMI may be divided in 3 groups of 1-year mortality risk, i.e., low (0 to 1 predictor: 29% and 31%), intermediate (2 to 3 predictors, 51% and 52%, respectively), and high (4 predictors: 83%). In conclusion, LVAD recipients with abnormal BMI experience lower survival, especially underweight patients. Four predictors of mortality have been identified for LVAD population with abnormal BMI, differentiating those a low-, intermediate-, and high risks of death. |
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| title_short |
Relation of Body Mass Index to Outcomes in Patients With Heart Failure Implanted With Left Ventricular Assist Devices |
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Flécher, Erwan Lelong, Bernard Chabanne, Céline Charton, Marion Goéminne, Céline Vincentelli, André Porterie, Jean Delmas, Clément Nubret, Karine Pernot, Mathieu Kindo, Michel Hoang Minh, Tam Gaudard, Philippe Rouvière, Philippe Sénage, Thomas Michel, Magali Boignard, Aude Chavanon, Olivier Verdonk, Constance Para, Marylou Pelcé, Edeline Gariboldi, Vlad Pozzi, Matteo Obadia, Jean-François Litzler, Pierre-Yves Anselme, Frédéric Blanchart, Katrien Babatasi, Gerard Garnier, Fabien Bielefeld, Marie Radu, Costin Hamon, David Bourguignon, Thierry Genet, Thibaud Eschalier, Romain D'Ostrevy, Nicolas Bories, Marie-Cécile Varlet, Emilie Vanhuyse, Fabrice Sadoul, Nicolas Leclercq, Christophe Martins, Raphaël P. |
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Flécher, Erwan Lelong, Bernard Chabanne, Céline Charton, Marion Goéminne, Céline Vincentelli, André Porterie, Jean Delmas, Clément Nubret, Karine Pernot, Mathieu Kindo, Michel Hoang Minh, Tam Gaudard, Philippe Rouvière, Philippe Sénage, Thomas Michel, Magali Boignard, Aude Chavanon, Olivier Verdonk, Constance Para, Marylou Pelcé, Edeline Gariboldi, Vlad Pozzi, Matteo Obadia, Jean-François Litzler, Pierre-Yves Anselme, Frédéric Blanchart, Katrien Babatasi, Gerard Garnier, Fabien Bielefeld, Marie Radu, Costin Hamon, David Bourguignon, Thierry Genet, Thibaud Eschalier, Romain D'Ostrevy, Nicolas Bories, Marie-Cécile Varlet, Emilie Vanhuyse, Fabrice Sadoul, Nicolas Leclercq, Christophe Martins, Raphaël P. |
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2024-07-06T23:55:25.442Z |
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| score |
7.3984118 |