Septuagenarian population has similar survival and outcomes to younger patients after left ventricular assist device implantation
Background: Left ventricular assist device (LVAD) implantation may be an attractive alternative therapeutic option for elderly patients with heart failure who are ineligible for heart transplantation.Aim: We aimed to describe the characteristics and outcomes of elderly patients (i.e. aged≥70 years)...
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Gespeichert in:
| Format: |
E-Artikel |
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| Sprache: |
Englisch |
| Erschienen: |
2020 |
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| Schlagwörter: |
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| Übergeordnetes Werk: |
Enthalten in: Archives of cardiovascular diseases - Issy-les-Moulineaux : Elsevier Masson, 2008, 113, Seite 701-709 |
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| Übergeordnetes Werk: |
volume:113 ; pages:701-709 |
| DOI / URN: |
10.1016/j.acvd.2020.05.018 |
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| 024 | 7 | |a 10.1016/j.acvd.2020.05.018 |2 doi | |
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| 100 | 1 | |a Galand, Vincent |e verfasserin |4 aut | |
| 245 | 1 | 0 | |a Septuagenarian population has similar survival and outcomes to younger patients after left ventricular assist device implantation |
| 264 | 1 | |c 2020 | |
| 336 | |a nicht spezifiziert |b zzz |2 rdacontent | ||
| 337 | |a Computermedien |b c |2 rdamedia | ||
| 338 | |a Online-Ressource |b cr |2 rdacarrier | ||
| 520 | |a Background: Left ventricular assist device (LVAD) implantation may be an attractive alternative therapeutic option for elderly patients with heart failure who are ineligible for heart transplantation.Aim: We aimed to describe the characteristics and outcomes of elderly patients (i.e. aged≥70 years) receiving an LVAD.Methods: This observational study was conducted in 19 centres between 2006 and 2016. Patients were divided into two groups–younger (aged<70 years) and elderly (aged≥70 years), based on age at time of LVAD implantation.Results: A total of 652 patients were included in the final analysis, and 74 patients (11.3%) were aged≥70 years at the time of LVAD implantation (maximal age 77.6 years). The proportion of elderly patients receiving an LVAD each year was constant, with a median of 10.6% (interquartile range 8.0–15.4%) per year, and all were implanted as destination therapy. Elderly and younger patients had similar durations of hospitalization in intensive care units and total lengths of hospital stays. Both age groups experienced similar rates of LVAD-related complications (i.e. stroke, bleeding, driveline infection and LVAD exchange), and the occurrence of LVAD complications did not impact survival in the elderly group compared with the younger group. Lastly, when compared with younger patients implanted as destination therapy, the elderly group also exhibited similar mid-term survival.Conclusion: This work strongly suggests that selected elderly adults can be scheduled for LVAD implantation. | ||
| 650 | 4 | |a Left ventricular assist device | |
| 650 | 4 | |a Elderly patients | |
| 650 | 4 | |a Septuagenarians | |
| 650 | 4 | |a Survival | |
| 650 | 4 | |a LVAD-related complications | |
| 700 | 1 | |a Flécher, Erwan |e verfasserin |4 aut | |
| 700 | 1 | |a Chabanne, Céline |e verfasserin |4 aut | |
| 700 | 1 | |a Lelong, Bernard |e verfasserin |4 aut | |
| 700 | 1 | |a Goéminne, Céline |e verfasserin |4 aut | |
| 700 | 1 | |a Vincentelli, André |e verfasserin |4 aut | |
| 700 | 1 | |a Delmas, Clément |e verfasserin |4 aut | |
| 700 | 1 | |a Dambrin, Camille |e verfasserin |4 aut | |
| 700 | 1 | |a Nubret, Karine |e verfasserin |4 aut | |
| 700 | 1 | |a Pernot, Mathieu |e verfasserin |4 aut | |
| 700 | 1 | |a Kindo, Michel |e verfasserin |4 aut | |
| 700 | 1 | |a Hoang Minh, Tam |e verfasserin |4 aut | |
| 700 | 1 | |a Gaudard, Philippe |e verfasserin |4 aut | |
| 700 | 1 | |a Frapier, Jean Marc |e verfasserin |4 aut | |
| 700 | 1 | |a Michel, Magali |e verfasserin |4 aut | |
| 700 | 1 | |a Sénage, Thomas |e verfasserin |4 aut | |
| 700 | 1 | |a Boignard, Aude |e verfasserin |4 aut | |
| 700 | 1 | |a Chavanon, Olivier |e verfasserin |4 aut | |
| 700 | 1 | |a Verdonk, Constance |e verfasserin |4 aut | |
| 700 | 1 | |a Para, Marylou |e verfasserin |4 aut | |
| 700 | 1 | |a Pelcé, Edeline |e verfasserin |4 aut | |
| 700 | 1 | |a Gariboldi, Vlad |e verfasserin |4 aut | |
| 700 | 1 | |a Pozzi, Matteo |e verfasserin |0 (orcid)0000-0001-6550-0872 |4 aut | |
| 700 | 1 | |a Obadia, Jean-François |e verfasserin |4 aut | |
| 700 | 1 | |a Litlzer, Pierre Yves |e verfasserin |4 aut | |
| 700 | 1 | |a Anselme, Frédéric |e verfasserin |4 aut | |
| 700 | 1 | |a Babatasi, Gerard |e verfasserin |4 aut | |
| 700 | 1 | |a Plane, Anne Flore |e verfasserin |4 aut | |
| 700 | 1 | |a Garnier, Fabien |e verfasserin |4 aut | |
| 700 | 1 | |a Bielefeld, Marie |e verfasserin |4 aut | |
| 700 | 1 | |a Hamon, David |e verfasserin |4 aut | |
| 700 | 1 | |a Radu, Costin |e verfasserin |4 aut | |
| 700 | 1 | |a Bourguignon, Thierry |e verfasserin |4 aut | |
| 700 | 1 | |a Genet, Thibaud |e verfasserin |4 aut | |
| 700 | 1 | |a Eschalier, Romain |e verfasserin |4 aut | |
| 700 | 1 | |a D’Ostrevy, Nicolas |e verfasserin |4 aut | |
| 700 | 1 | |a Bories, Marie-Cécile |e verfasserin |4 aut | |
| 700 | 1 | |a Marijon, Eloi |e verfasserin |4 aut | |
| 700 | 1 | |a Vanhuyse, Fabrice |e verfasserin |4 aut | |
| 700 | 1 | |a Blangy, Hugues |e verfasserin |4 aut | |
| 700 | 1 | |a Leclercq, Christophe |e verfasserin |4 aut | |
| 700 | 1 | |a Martins, Raphaël P. |e verfasserin |4 aut | |
| 773 | 0 | 8 | |i Enthalten in |t Archives of cardiovascular diseases |d Issy-les-Moulineaux : Elsevier Masson, 2008 |g 113, Seite 701-709 |h Online-Ressource |w (DE-627)568486064 |w (DE-600)2428616-3 |w (DE-576)286490358 |x 1875-2128 |7 nnns |
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| 936 | b | k | |a 44.85 |j Kardiologie |j Angiologie |
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10.1016/j.acvd.2020.05.018 doi (DE-627)ELV005086620 (ELSEVIER)S1875-2136(20)30183-2 DE-627 ger DE-627 rda eng 610 DE-600 44.85 bkl Galand, Vincent verfasserin aut Septuagenarian population has similar survival and outcomes to younger patients after left ventricular assist device implantation 2020 nicht spezifiziert zzz rdacontent Computermedien c rdamedia Online-Ressource cr rdacarrier Background: Left ventricular assist device (LVAD) implantation may be an attractive alternative therapeutic option for elderly patients with heart failure who are ineligible for heart transplantation.Aim: We aimed to describe the characteristics and outcomes of elderly patients (i.e. aged≥70 years) receiving an LVAD.Methods: This observational study was conducted in 19 centres between 2006 and 2016. Patients were divided into two groups–younger (aged<70 years) and elderly (aged≥70 years), based on age at time of LVAD implantation.Results: A total of 652 patients were included in the final analysis, and 74 patients (11.3%) were aged≥70 years at the time of LVAD implantation (maximal age 77.6 years). The proportion of elderly patients receiving an LVAD each year was constant, with a median of 10.6% (interquartile range 8.0–15.4%) per year, and all were implanted as destination therapy. Elderly and younger patients had similar durations of hospitalization in intensive care units and total lengths of hospital stays. Both age groups experienced similar rates of LVAD-related complications (i.e. stroke, bleeding, driveline infection and LVAD exchange), and the occurrence of LVAD complications did not impact survival in the elderly group compared with the younger group. Lastly, when compared with younger patients implanted as destination therapy, the elderly group also exhibited similar mid-term survival.Conclusion: This work strongly suggests that selected elderly adults can be scheduled for LVAD implantation. Left ventricular assist device Elderly patients Septuagenarians Survival LVAD-related complications Flécher, Erwan verfasserin aut Chabanne, Céline verfasserin aut Lelong, Bernard verfasserin aut Goéminne, Céline verfasserin aut Vincentelli, André verfasserin aut Delmas, Clément verfasserin aut Dambrin, Camille verfasserin aut Nubret, Karine verfasserin aut Pernot, Mathieu verfasserin aut Kindo, Michel verfasserin aut Hoang Minh, Tam verfasserin aut Gaudard, Philippe verfasserin aut Frapier, Jean Marc verfasserin aut Michel, Magali verfasserin aut Sénage, Thomas verfasserin aut Boignard, Aude verfasserin aut Chavanon, Olivier verfasserin aut Verdonk, Constance verfasserin aut Para, Marylou verfasserin aut Pelcé, Edeline verfasserin aut Gariboldi, Vlad verfasserin aut Pozzi, Matteo verfasserin (orcid)0000-0001-6550-0872 aut Obadia, Jean-François verfasserin aut Litlzer, Pierre Yves verfasserin aut Anselme, Frédéric verfasserin aut Babatasi, Gerard verfasserin aut Plane, Anne Flore verfasserin aut Garnier, Fabien verfasserin aut Bielefeld, Marie verfasserin aut Hamon, David verfasserin aut Radu, Costin verfasserin aut Bourguignon, Thierry verfasserin aut Genet, Thibaud verfasserin aut Eschalier, Romain verfasserin aut D’Ostrevy, Nicolas verfasserin aut Bories, Marie-Cécile verfasserin aut Marijon, Eloi verfasserin aut Vanhuyse, Fabrice verfasserin aut Blangy, Hugues verfasserin aut Leclercq, Christophe verfasserin aut Martins, Raphaël P. verfasserin aut Enthalten in Archives of cardiovascular diseases Issy-les-Moulineaux : Elsevier Masson, 2008 113, Seite 701-709 Online-Ressource (DE-627)568486064 (DE-600)2428616-3 (DE-576)286490358 1875-2128 nnns volume:113 pages:701-709 GBV_USEFLAG_U SYSFLAG_U GBV_ELV SSG-OLC-PHA GBV_ILN_20 GBV_ILN_22 GBV_ILN_23 GBV_ILN_24 GBV_ILN_31 GBV_ILN_32 GBV_ILN_39 GBV_ILN_40 GBV_ILN_60 GBV_ILN_62 GBV_ILN_63 GBV_ILN_65 GBV_ILN_69 GBV_ILN_70 GBV_ILN_73 GBV_ILN_74 GBV_ILN_90 GBV_ILN_95 GBV_ILN_100 GBV_ILN_101 GBV_ILN_105 GBV_ILN_110 GBV_ILN_151 GBV_ILN_161 GBV_ILN_170 GBV_ILN_206 GBV_ILN_213 GBV_ILN_224 GBV_ILN_230 GBV_ILN_285 GBV_ILN_293 GBV_ILN_370 GBV_ILN_602 GBV_ILN_702 GBV_ILN_2001 GBV_ILN_2003 GBV_ILN_2004 GBV_ILN_2005 GBV_ILN_2006 GBV_ILN_2008 GBV_ILN_2011 GBV_ILN_2014 GBV_ILN_2015 GBV_ILN_2020 GBV_ILN_2021 GBV_ILN_2025 GBV_ILN_2026 GBV_ILN_2027 GBV_ILN_2034 GBV_ILN_2038 GBV_ILN_2044 GBV_ILN_2048 GBV_ILN_2049 GBV_ILN_2050 GBV_ILN_2055 GBV_ILN_2056 GBV_ILN_2059 GBV_ILN_2061 GBV_ILN_2064 GBV_ILN_2065 GBV_ILN_2068 GBV_ILN_2088 GBV_ILN_2111 GBV_ILN_2112 GBV_ILN_2113 GBV_ILN_2118 GBV_ILN_2122 GBV_ILN_2129 GBV_ILN_2143 GBV_ILN_2147 GBV_ILN_2148 GBV_ILN_2152 GBV_ILN_2153 GBV_ILN_2190 GBV_ILN_2232 GBV_ILN_2470 GBV_ILN_2507 GBV_ILN_2522 GBV_ILN_4012 GBV_ILN_4035 GBV_ILN_4037 GBV_ILN_4046 GBV_ILN_4112 GBV_ILN_4125 GBV_ILN_4126 GBV_ILN_4242 GBV_ILN_4249 GBV_ILN_4251 GBV_ILN_4305 GBV_ILN_4306 GBV_ILN_4307 GBV_ILN_4313 GBV_ILN_4322 GBV_ILN_4323 GBV_ILN_4324 GBV_ILN_4325 GBV_ILN_4326 GBV_ILN_4333 GBV_ILN_4334 GBV_ILN_4335 GBV_ILN_4338 GBV_ILN_4367 GBV_ILN_4393 GBV_ILN_4700 44.85 Kardiologie Angiologie AR 113 701-709 |
| spelling |
10.1016/j.acvd.2020.05.018 doi (DE-627)ELV005086620 (ELSEVIER)S1875-2136(20)30183-2 DE-627 ger DE-627 rda eng 610 DE-600 44.85 bkl Galand, Vincent verfasserin aut Septuagenarian population has similar survival and outcomes to younger patients after left ventricular assist device implantation 2020 nicht spezifiziert zzz rdacontent Computermedien c rdamedia Online-Ressource cr rdacarrier Background: Left ventricular assist device (LVAD) implantation may be an attractive alternative therapeutic option for elderly patients with heart failure who are ineligible for heart transplantation.Aim: We aimed to describe the characteristics and outcomes of elderly patients (i.e. aged≥70 years) receiving an LVAD.Methods: This observational study was conducted in 19 centres between 2006 and 2016. Patients were divided into two groups–younger (aged<70 years) and elderly (aged≥70 years), based on age at time of LVAD implantation.Results: A total of 652 patients were included in the final analysis, and 74 patients (11.3%) were aged≥70 years at the time of LVAD implantation (maximal age 77.6 years). The proportion of elderly patients receiving an LVAD each year was constant, with a median of 10.6% (interquartile range 8.0–15.4%) per year, and all were implanted as destination therapy. Elderly and younger patients had similar durations of hospitalization in intensive care units and total lengths of hospital stays. Both age groups experienced similar rates of LVAD-related complications (i.e. stroke, bleeding, driveline infection and LVAD exchange), and the occurrence of LVAD complications did not impact survival in the elderly group compared with the younger group. Lastly, when compared with younger patients implanted as destination therapy, the elderly group also exhibited similar mid-term survival.Conclusion: This work strongly suggests that selected elderly adults can be scheduled for LVAD implantation. Left ventricular assist device Elderly patients Septuagenarians Survival LVAD-related complications Flécher, Erwan verfasserin aut Chabanne, Céline verfasserin aut Lelong, Bernard verfasserin aut Goéminne, Céline verfasserin aut Vincentelli, André verfasserin aut Delmas, Clément verfasserin aut Dambrin, Camille verfasserin aut Nubret, Karine verfasserin aut Pernot, Mathieu verfasserin aut Kindo, Michel verfasserin aut Hoang Minh, Tam verfasserin aut Gaudard, Philippe verfasserin aut Frapier, Jean Marc verfasserin aut Michel, Magali verfasserin aut Sénage, Thomas verfasserin aut Boignard, Aude verfasserin aut Chavanon, Olivier verfasserin aut Verdonk, Constance verfasserin aut Para, Marylou verfasserin aut Pelcé, Edeline verfasserin aut Gariboldi, Vlad verfasserin aut Pozzi, Matteo verfasserin (orcid)0000-0001-6550-0872 aut Obadia, Jean-François verfasserin aut Litlzer, Pierre Yves verfasserin aut Anselme, Frédéric verfasserin aut Babatasi, Gerard verfasserin aut Plane, Anne Flore verfasserin aut Garnier, Fabien verfasserin aut Bielefeld, Marie verfasserin aut Hamon, David verfasserin aut Radu, Costin verfasserin aut Bourguignon, Thierry verfasserin aut Genet, Thibaud verfasserin aut Eschalier, Romain verfasserin aut D’Ostrevy, Nicolas verfasserin aut Bories, Marie-Cécile verfasserin aut Marijon, Eloi verfasserin aut Vanhuyse, Fabrice verfasserin aut Blangy, Hugues verfasserin aut Leclercq, Christophe verfasserin aut Martins, Raphaël P. verfasserin aut Enthalten in Archives of cardiovascular diseases Issy-les-Moulineaux : Elsevier Masson, 2008 113, Seite 701-709 Online-Ressource (DE-627)568486064 (DE-600)2428616-3 (DE-576)286490358 1875-2128 nnns volume:113 pages:701-709 GBV_USEFLAG_U SYSFLAG_U GBV_ELV SSG-OLC-PHA GBV_ILN_20 GBV_ILN_22 GBV_ILN_23 GBV_ILN_24 GBV_ILN_31 GBV_ILN_32 GBV_ILN_39 GBV_ILN_40 GBV_ILN_60 GBV_ILN_62 GBV_ILN_63 GBV_ILN_65 GBV_ILN_69 GBV_ILN_70 GBV_ILN_73 GBV_ILN_74 GBV_ILN_90 GBV_ILN_95 GBV_ILN_100 GBV_ILN_101 GBV_ILN_105 GBV_ILN_110 GBV_ILN_151 GBV_ILN_161 GBV_ILN_170 GBV_ILN_206 GBV_ILN_213 GBV_ILN_224 GBV_ILN_230 GBV_ILN_285 GBV_ILN_293 GBV_ILN_370 GBV_ILN_602 GBV_ILN_702 GBV_ILN_2001 GBV_ILN_2003 GBV_ILN_2004 GBV_ILN_2005 GBV_ILN_2006 GBV_ILN_2008 GBV_ILN_2011 GBV_ILN_2014 GBV_ILN_2015 GBV_ILN_2020 GBV_ILN_2021 GBV_ILN_2025 GBV_ILN_2026 GBV_ILN_2027 GBV_ILN_2034 GBV_ILN_2038 GBV_ILN_2044 GBV_ILN_2048 GBV_ILN_2049 GBV_ILN_2050 GBV_ILN_2055 GBV_ILN_2056 GBV_ILN_2059 GBV_ILN_2061 GBV_ILN_2064 GBV_ILN_2065 GBV_ILN_2068 GBV_ILN_2088 GBV_ILN_2111 GBV_ILN_2112 GBV_ILN_2113 GBV_ILN_2118 GBV_ILN_2122 GBV_ILN_2129 GBV_ILN_2143 GBV_ILN_2147 GBV_ILN_2148 GBV_ILN_2152 GBV_ILN_2153 GBV_ILN_2190 GBV_ILN_2232 GBV_ILN_2470 GBV_ILN_2507 GBV_ILN_2522 GBV_ILN_4012 GBV_ILN_4035 GBV_ILN_4037 GBV_ILN_4046 GBV_ILN_4112 GBV_ILN_4125 GBV_ILN_4126 GBV_ILN_4242 GBV_ILN_4249 GBV_ILN_4251 GBV_ILN_4305 GBV_ILN_4306 GBV_ILN_4307 GBV_ILN_4313 GBV_ILN_4322 GBV_ILN_4323 GBV_ILN_4324 GBV_ILN_4325 GBV_ILN_4326 GBV_ILN_4333 GBV_ILN_4334 GBV_ILN_4335 GBV_ILN_4338 GBV_ILN_4367 GBV_ILN_4393 GBV_ILN_4700 44.85 Kardiologie Angiologie AR 113 701-709 |
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10.1016/j.acvd.2020.05.018 doi (DE-627)ELV005086620 (ELSEVIER)S1875-2136(20)30183-2 DE-627 ger DE-627 rda eng 610 DE-600 44.85 bkl Galand, Vincent verfasserin aut Septuagenarian population has similar survival and outcomes to younger patients after left ventricular assist device implantation 2020 nicht spezifiziert zzz rdacontent Computermedien c rdamedia Online-Ressource cr rdacarrier Background: Left ventricular assist device (LVAD) implantation may be an attractive alternative therapeutic option for elderly patients with heart failure who are ineligible for heart transplantation.Aim: We aimed to describe the characteristics and outcomes of elderly patients (i.e. aged≥70 years) receiving an LVAD.Methods: This observational study was conducted in 19 centres between 2006 and 2016. Patients were divided into two groups–younger (aged<70 years) and elderly (aged≥70 years), based on age at time of LVAD implantation.Results: A total of 652 patients were included in the final analysis, and 74 patients (11.3%) were aged≥70 years at the time of LVAD implantation (maximal age 77.6 years). The proportion of elderly patients receiving an LVAD each year was constant, with a median of 10.6% (interquartile range 8.0–15.4%) per year, and all were implanted as destination therapy. Elderly and younger patients had similar durations of hospitalization in intensive care units and total lengths of hospital stays. Both age groups experienced similar rates of LVAD-related complications (i.e. stroke, bleeding, driveline infection and LVAD exchange), and the occurrence of LVAD complications did not impact survival in the elderly group compared with the younger group. Lastly, when compared with younger patients implanted as destination therapy, the elderly group also exhibited similar mid-term survival.Conclusion: This work strongly suggests that selected elderly adults can be scheduled for LVAD implantation. Left ventricular assist device Elderly patients Septuagenarians Survival LVAD-related complications Flécher, Erwan verfasserin aut Chabanne, Céline verfasserin aut Lelong, Bernard verfasserin aut Goéminne, Céline verfasserin aut Vincentelli, André verfasserin aut Delmas, Clément verfasserin aut Dambrin, Camille verfasserin aut Nubret, Karine verfasserin aut Pernot, Mathieu verfasserin aut Kindo, Michel verfasserin aut Hoang Minh, Tam verfasserin aut Gaudard, Philippe verfasserin aut Frapier, Jean Marc verfasserin aut Michel, Magali verfasserin aut Sénage, Thomas verfasserin aut Boignard, Aude verfasserin aut Chavanon, Olivier verfasserin aut Verdonk, Constance verfasserin aut Para, Marylou verfasserin aut Pelcé, Edeline verfasserin aut Gariboldi, Vlad verfasserin aut Pozzi, Matteo verfasserin (orcid)0000-0001-6550-0872 aut Obadia, Jean-François verfasserin aut Litlzer, Pierre Yves verfasserin aut Anselme, Frédéric verfasserin aut Babatasi, Gerard verfasserin aut Plane, Anne Flore verfasserin aut Garnier, Fabien verfasserin aut Bielefeld, Marie verfasserin aut Hamon, David verfasserin aut Radu, Costin verfasserin aut Bourguignon, Thierry verfasserin aut Genet, Thibaud verfasserin aut Eschalier, Romain verfasserin aut D’Ostrevy, Nicolas verfasserin aut Bories, Marie-Cécile verfasserin aut Marijon, Eloi verfasserin aut Vanhuyse, Fabrice verfasserin aut Blangy, Hugues verfasserin aut Leclercq, Christophe verfasserin aut Martins, Raphaël P. verfasserin aut Enthalten in Archives of cardiovascular diseases Issy-les-Moulineaux : Elsevier Masson, 2008 113, Seite 701-709 Online-Ressource (DE-627)568486064 (DE-600)2428616-3 (DE-576)286490358 1875-2128 nnns volume:113 pages:701-709 GBV_USEFLAG_U SYSFLAG_U GBV_ELV SSG-OLC-PHA GBV_ILN_20 GBV_ILN_22 GBV_ILN_23 GBV_ILN_24 GBV_ILN_31 GBV_ILN_32 GBV_ILN_39 GBV_ILN_40 GBV_ILN_60 GBV_ILN_62 GBV_ILN_63 GBV_ILN_65 GBV_ILN_69 GBV_ILN_70 GBV_ILN_73 GBV_ILN_74 GBV_ILN_90 GBV_ILN_95 GBV_ILN_100 GBV_ILN_101 GBV_ILN_105 GBV_ILN_110 GBV_ILN_151 GBV_ILN_161 GBV_ILN_170 GBV_ILN_206 GBV_ILN_213 GBV_ILN_224 GBV_ILN_230 GBV_ILN_285 GBV_ILN_293 GBV_ILN_370 GBV_ILN_602 GBV_ILN_702 GBV_ILN_2001 GBV_ILN_2003 GBV_ILN_2004 GBV_ILN_2005 GBV_ILN_2006 GBV_ILN_2008 GBV_ILN_2011 GBV_ILN_2014 GBV_ILN_2015 GBV_ILN_2020 GBV_ILN_2021 GBV_ILN_2025 GBV_ILN_2026 GBV_ILN_2027 GBV_ILN_2034 GBV_ILN_2038 GBV_ILN_2044 GBV_ILN_2048 GBV_ILN_2049 GBV_ILN_2050 GBV_ILN_2055 GBV_ILN_2056 GBV_ILN_2059 GBV_ILN_2061 GBV_ILN_2064 GBV_ILN_2065 GBV_ILN_2068 GBV_ILN_2088 GBV_ILN_2111 GBV_ILN_2112 GBV_ILN_2113 GBV_ILN_2118 GBV_ILN_2122 GBV_ILN_2129 GBV_ILN_2143 GBV_ILN_2147 GBV_ILN_2148 GBV_ILN_2152 GBV_ILN_2153 GBV_ILN_2190 GBV_ILN_2232 GBV_ILN_2470 GBV_ILN_2507 GBV_ILN_2522 GBV_ILN_4012 GBV_ILN_4035 GBV_ILN_4037 GBV_ILN_4046 GBV_ILN_4112 GBV_ILN_4125 GBV_ILN_4126 GBV_ILN_4242 GBV_ILN_4249 GBV_ILN_4251 GBV_ILN_4305 GBV_ILN_4306 GBV_ILN_4307 GBV_ILN_4313 GBV_ILN_4322 GBV_ILN_4323 GBV_ILN_4324 GBV_ILN_4325 GBV_ILN_4326 GBV_ILN_4333 GBV_ILN_4334 GBV_ILN_4335 GBV_ILN_4338 GBV_ILN_4367 GBV_ILN_4393 GBV_ILN_4700 44.85 Kardiologie Angiologie AR 113 701-709 |
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10.1016/j.acvd.2020.05.018 doi (DE-627)ELV005086620 (ELSEVIER)S1875-2136(20)30183-2 DE-627 ger DE-627 rda eng 610 DE-600 44.85 bkl Galand, Vincent verfasserin aut Septuagenarian population has similar survival and outcomes to younger patients after left ventricular assist device implantation 2020 nicht spezifiziert zzz rdacontent Computermedien c rdamedia Online-Ressource cr rdacarrier Background: Left ventricular assist device (LVAD) implantation may be an attractive alternative therapeutic option for elderly patients with heart failure who are ineligible for heart transplantation.Aim: We aimed to describe the characteristics and outcomes of elderly patients (i.e. aged≥70 years) receiving an LVAD.Methods: This observational study was conducted in 19 centres between 2006 and 2016. Patients were divided into two groups–younger (aged<70 years) and elderly (aged≥70 years), based on age at time of LVAD implantation.Results: A total of 652 patients were included in the final analysis, and 74 patients (11.3%) were aged≥70 years at the time of LVAD implantation (maximal age 77.6 years). The proportion of elderly patients receiving an LVAD each year was constant, with a median of 10.6% (interquartile range 8.0–15.4%) per year, and all were implanted as destination therapy. Elderly and younger patients had similar durations of hospitalization in intensive care units and total lengths of hospital stays. Both age groups experienced similar rates of LVAD-related complications (i.e. stroke, bleeding, driveline infection and LVAD exchange), and the occurrence of LVAD complications did not impact survival in the elderly group compared with the younger group. Lastly, when compared with younger patients implanted as destination therapy, the elderly group also exhibited similar mid-term survival.Conclusion: This work strongly suggests that selected elderly adults can be scheduled for LVAD implantation. Left ventricular assist device Elderly patients Septuagenarians Survival LVAD-related complications Flécher, Erwan verfasserin aut Chabanne, Céline verfasserin aut Lelong, Bernard verfasserin aut Goéminne, Céline verfasserin aut Vincentelli, André verfasserin aut Delmas, Clément verfasserin aut Dambrin, Camille verfasserin aut Nubret, Karine verfasserin aut Pernot, Mathieu verfasserin aut Kindo, Michel verfasserin aut Hoang Minh, Tam verfasserin aut Gaudard, Philippe verfasserin aut Frapier, Jean Marc verfasserin aut Michel, Magali verfasserin aut Sénage, Thomas verfasserin aut Boignard, Aude verfasserin aut Chavanon, Olivier verfasserin aut Verdonk, Constance verfasserin aut Para, Marylou verfasserin aut Pelcé, Edeline verfasserin aut Gariboldi, Vlad verfasserin aut Pozzi, Matteo verfasserin (orcid)0000-0001-6550-0872 aut Obadia, Jean-François verfasserin aut Litlzer, Pierre Yves verfasserin aut Anselme, Frédéric verfasserin aut Babatasi, Gerard verfasserin aut Plane, Anne Flore verfasserin aut Garnier, Fabien verfasserin aut Bielefeld, Marie verfasserin aut Hamon, David verfasserin aut Radu, Costin verfasserin aut Bourguignon, Thierry verfasserin aut Genet, Thibaud verfasserin aut Eschalier, Romain verfasserin aut D’Ostrevy, Nicolas verfasserin aut Bories, Marie-Cécile verfasserin aut Marijon, Eloi verfasserin aut Vanhuyse, Fabrice verfasserin aut Blangy, Hugues verfasserin aut Leclercq, Christophe verfasserin aut Martins, Raphaël P. verfasserin aut Enthalten in Archives of cardiovascular diseases Issy-les-Moulineaux : Elsevier Masson, 2008 113, Seite 701-709 Online-Ressource (DE-627)568486064 (DE-600)2428616-3 (DE-576)286490358 1875-2128 nnns volume:113 pages:701-709 GBV_USEFLAG_U SYSFLAG_U GBV_ELV SSG-OLC-PHA GBV_ILN_20 GBV_ILN_22 GBV_ILN_23 GBV_ILN_24 GBV_ILN_31 GBV_ILN_32 GBV_ILN_39 GBV_ILN_40 GBV_ILN_60 GBV_ILN_62 GBV_ILN_63 GBV_ILN_65 GBV_ILN_69 GBV_ILN_70 GBV_ILN_73 GBV_ILN_74 GBV_ILN_90 GBV_ILN_95 GBV_ILN_100 GBV_ILN_101 GBV_ILN_105 GBV_ILN_110 GBV_ILN_151 GBV_ILN_161 GBV_ILN_170 GBV_ILN_206 GBV_ILN_213 GBV_ILN_224 GBV_ILN_230 GBV_ILN_285 GBV_ILN_293 GBV_ILN_370 GBV_ILN_602 GBV_ILN_702 GBV_ILN_2001 GBV_ILN_2003 GBV_ILN_2004 GBV_ILN_2005 GBV_ILN_2006 GBV_ILN_2008 GBV_ILN_2011 GBV_ILN_2014 GBV_ILN_2015 GBV_ILN_2020 GBV_ILN_2021 GBV_ILN_2025 GBV_ILN_2026 GBV_ILN_2027 GBV_ILN_2034 GBV_ILN_2038 GBV_ILN_2044 GBV_ILN_2048 GBV_ILN_2049 GBV_ILN_2050 GBV_ILN_2055 GBV_ILN_2056 GBV_ILN_2059 GBV_ILN_2061 GBV_ILN_2064 GBV_ILN_2065 GBV_ILN_2068 GBV_ILN_2088 GBV_ILN_2111 GBV_ILN_2112 GBV_ILN_2113 GBV_ILN_2118 GBV_ILN_2122 GBV_ILN_2129 GBV_ILN_2143 GBV_ILN_2147 GBV_ILN_2148 GBV_ILN_2152 GBV_ILN_2153 GBV_ILN_2190 GBV_ILN_2232 GBV_ILN_2470 GBV_ILN_2507 GBV_ILN_2522 GBV_ILN_4012 GBV_ILN_4035 GBV_ILN_4037 GBV_ILN_4046 GBV_ILN_4112 GBV_ILN_4125 GBV_ILN_4126 GBV_ILN_4242 GBV_ILN_4249 GBV_ILN_4251 GBV_ILN_4305 GBV_ILN_4306 GBV_ILN_4307 GBV_ILN_4313 GBV_ILN_4322 GBV_ILN_4323 GBV_ILN_4324 GBV_ILN_4325 GBV_ILN_4326 GBV_ILN_4333 GBV_ILN_4334 GBV_ILN_4335 GBV_ILN_4338 GBV_ILN_4367 GBV_ILN_4393 GBV_ILN_4700 44.85 Kardiologie Angiologie AR 113 701-709 |
| allfieldsSound |
10.1016/j.acvd.2020.05.018 doi (DE-627)ELV005086620 (ELSEVIER)S1875-2136(20)30183-2 DE-627 ger DE-627 rda eng 610 DE-600 44.85 bkl Galand, Vincent verfasserin aut Septuagenarian population has similar survival and outcomes to younger patients after left ventricular assist device implantation 2020 nicht spezifiziert zzz rdacontent Computermedien c rdamedia Online-Ressource cr rdacarrier Background: Left ventricular assist device (LVAD) implantation may be an attractive alternative therapeutic option for elderly patients with heart failure who are ineligible for heart transplantation.Aim: We aimed to describe the characteristics and outcomes of elderly patients (i.e. aged≥70 years) receiving an LVAD.Methods: This observational study was conducted in 19 centres between 2006 and 2016. Patients were divided into two groups–younger (aged<70 years) and elderly (aged≥70 years), based on age at time of LVAD implantation.Results: A total of 652 patients were included in the final analysis, and 74 patients (11.3%) were aged≥70 years at the time of LVAD implantation (maximal age 77.6 years). The proportion of elderly patients receiving an LVAD each year was constant, with a median of 10.6% (interquartile range 8.0–15.4%) per year, and all were implanted as destination therapy. Elderly and younger patients had similar durations of hospitalization in intensive care units and total lengths of hospital stays. Both age groups experienced similar rates of LVAD-related complications (i.e. stroke, bleeding, driveline infection and LVAD exchange), and the occurrence of LVAD complications did not impact survival in the elderly group compared with the younger group. Lastly, when compared with younger patients implanted as destination therapy, the elderly group also exhibited similar mid-term survival.Conclusion: This work strongly suggests that selected elderly adults can be scheduled for LVAD implantation. Left ventricular assist device Elderly patients Septuagenarians Survival LVAD-related complications Flécher, Erwan verfasserin aut Chabanne, Céline verfasserin aut Lelong, Bernard verfasserin aut Goéminne, Céline verfasserin aut Vincentelli, André verfasserin aut Delmas, Clément verfasserin aut Dambrin, Camille verfasserin aut Nubret, Karine verfasserin aut Pernot, Mathieu verfasserin aut Kindo, Michel verfasserin aut Hoang Minh, Tam verfasserin aut Gaudard, Philippe verfasserin aut Frapier, Jean Marc verfasserin aut Michel, Magali verfasserin aut Sénage, Thomas verfasserin aut Boignard, Aude verfasserin aut Chavanon, Olivier verfasserin aut Verdonk, Constance verfasserin aut Para, Marylou verfasserin aut Pelcé, Edeline verfasserin aut Gariboldi, Vlad verfasserin aut Pozzi, Matteo verfasserin (orcid)0000-0001-6550-0872 aut Obadia, Jean-François verfasserin aut Litlzer, Pierre Yves verfasserin aut Anselme, Frédéric verfasserin aut Babatasi, Gerard verfasserin aut Plane, Anne Flore verfasserin aut Garnier, Fabien verfasserin aut Bielefeld, Marie verfasserin aut Hamon, David verfasserin aut Radu, Costin verfasserin aut Bourguignon, Thierry verfasserin aut Genet, Thibaud verfasserin aut Eschalier, Romain verfasserin aut D’Ostrevy, Nicolas verfasserin aut Bories, Marie-Cécile verfasserin aut Marijon, Eloi verfasserin aut Vanhuyse, Fabrice verfasserin aut Blangy, Hugues verfasserin aut Leclercq, Christophe verfasserin aut Martins, Raphaël P. verfasserin aut Enthalten in Archives of cardiovascular diseases Issy-les-Moulineaux : Elsevier Masson, 2008 113, Seite 701-709 Online-Ressource (DE-627)568486064 (DE-600)2428616-3 (DE-576)286490358 1875-2128 nnns volume:113 pages:701-709 GBV_USEFLAG_U SYSFLAG_U GBV_ELV SSG-OLC-PHA GBV_ILN_20 GBV_ILN_22 GBV_ILN_23 GBV_ILN_24 GBV_ILN_31 GBV_ILN_32 GBV_ILN_39 GBV_ILN_40 GBV_ILN_60 GBV_ILN_62 GBV_ILN_63 GBV_ILN_65 GBV_ILN_69 GBV_ILN_70 GBV_ILN_73 GBV_ILN_74 GBV_ILN_90 GBV_ILN_95 GBV_ILN_100 GBV_ILN_101 GBV_ILN_105 GBV_ILN_110 GBV_ILN_151 GBV_ILN_161 GBV_ILN_170 GBV_ILN_206 GBV_ILN_213 GBV_ILN_224 GBV_ILN_230 GBV_ILN_285 GBV_ILN_293 GBV_ILN_370 GBV_ILN_602 GBV_ILN_702 GBV_ILN_2001 GBV_ILN_2003 GBV_ILN_2004 GBV_ILN_2005 GBV_ILN_2006 GBV_ILN_2008 GBV_ILN_2011 GBV_ILN_2014 GBV_ILN_2015 GBV_ILN_2020 GBV_ILN_2021 GBV_ILN_2025 GBV_ILN_2026 GBV_ILN_2027 GBV_ILN_2034 GBV_ILN_2038 GBV_ILN_2044 GBV_ILN_2048 GBV_ILN_2049 GBV_ILN_2050 GBV_ILN_2055 GBV_ILN_2056 GBV_ILN_2059 GBV_ILN_2061 GBV_ILN_2064 GBV_ILN_2065 GBV_ILN_2068 GBV_ILN_2088 GBV_ILN_2111 GBV_ILN_2112 GBV_ILN_2113 GBV_ILN_2118 GBV_ILN_2122 GBV_ILN_2129 GBV_ILN_2143 GBV_ILN_2147 GBV_ILN_2148 GBV_ILN_2152 GBV_ILN_2153 GBV_ILN_2190 GBV_ILN_2232 GBV_ILN_2470 GBV_ILN_2507 GBV_ILN_2522 GBV_ILN_4012 GBV_ILN_4035 GBV_ILN_4037 GBV_ILN_4046 GBV_ILN_4112 GBV_ILN_4125 GBV_ILN_4126 GBV_ILN_4242 GBV_ILN_4249 GBV_ILN_4251 GBV_ILN_4305 GBV_ILN_4306 GBV_ILN_4307 GBV_ILN_4313 GBV_ILN_4322 GBV_ILN_4323 GBV_ILN_4324 GBV_ILN_4325 GBV_ILN_4326 GBV_ILN_4333 GBV_ILN_4334 GBV_ILN_4335 GBV_ILN_4338 GBV_ILN_4367 GBV_ILN_4393 GBV_ILN_4700 44.85 Kardiologie Angiologie AR 113 701-709 |
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Left ventricular assist device Elderly patients Septuagenarians Survival LVAD-related complications |
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Galand, Vincent @@aut@@ Flécher, Erwan @@aut@@ Chabanne, Céline @@aut@@ Lelong, Bernard @@aut@@ Goéminne, Céline @@aut@@ Vincentelli, André @@aut@@ Delmas, Clément @@aut@@ Dambrin, Camille @@aut@@ Nubret, Karine @@aut@@ Pernot, Mathieu @@aut@@ Kindo, Michel @@aut@@ Hoang Minh, Tam @@aut@@ Gaudard, Philippe @@aut@@ Frapier, Jean Marc @@aut@@ Michel, Magali @@aut@@ Sénage, Thomas @@aut@@ Boignard, Aude @@aut@@ Chavanon, Olivier @@aut@@ Verdonk, Constance @@aut@@ Para, Marylou @@aut@@ Pelcé, Edeline @@aut@@ Gariboldi, Vlad @@aut@@ Pozzi, Matteo @@aut@@ Obadia, Jean-François @@aut@@ Litlzer, Pierre Yves @@aut@@ Anselme, Frédéric @@aut@@ Babatasi, Gerard @@aut@@ Plane, Anne Flore @@aut@@ Garnier, Fabien @@aut@@ Bielefeld, Marie @@aut@@ Hamon, David @@aut@@ Radu, Costin @@aut@@ Bourguignon, Thierry @@aut@@ Genet, Thibaud @@aut@@ Eschalier, Romain @@aut@@ D’Ostrevy, Nicolas @@aut@@ Bories, Marie-Cécile @@aut@@ Marijon, Eloi @@aut@@ Vanhuyse, Fabrice @@aut@@ Blangy, Hugues @@aut@@ Leclercq, Christophe @@aut@@ Martins, Raphaël P. @@aut@@ |
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2020-01-01T00:00:00Z |
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<?xml version="1.0" encoding="UTF-8"?><collection xmlns="http://www.loc.gov/MARC21/slim"><record><leader>01000caa a22002652 4500</leader><controlfield tag="001">ELV005086620</controlfield><controlfield tag="003">DE-627</controlfield><controlfield tag="005">20230524145856.0</controlfield><controlfield tag="007">cr uuu---uuuuu</controlfield><controlfield tag="008">230503s2020 xx |||||o 00| ||eng c</controlfield><datafield tag="024" ind1="7" ind2=" "><subfield code="a">10.1016/j.acvd.2020.05.018</subfield><subfield code="2">doi</subfield></datafield><datafield tag="035" ind1=" " ind2=" "><subfield code="a">(DE-627)ELV005086620</subfield></datafield><datafield tag="035" ind1=" " ind2=" "><subfield code="a">(ELSEVIER)S1875-2136(20)30183-2</subfield></datafield><datafield tag="040" ind1=" " ind2=" "><subfield code="a">DE-627</subfield><subfield code="b">ger</subfield><subfield code="c">DE-627</subfield><subfield code="e">rda</subfield></datafield><datafield tag="041" ind1=" " ind2=" "><subfield code="a">eng</subfield></datafield><datafield tag="082" ind1="0" ind2="4"><subfield code="a">610</subfield><subfield code="q">DE-600</subfield></datafield><datafield tag="084" ind1=" " ind2=" "><subfield code="a">44.85</subfield><subfield code="2">bkl</subfield></datafield><datafield tag="100" ind1="1" ind2=" "><subfield code="a">Galand, Vincent</subfield><subfield code="e">verfasserin</subfield><subfield code="4">aut</subfield></datafield><datafield tag="245" ind1="1" ind2="0"><subfield code="a">Septuagenarian population has similar survival and outcomes to younger patients after left ventricular assist device implantation</subfield></datafield><datafield tag="264" ind1=" " ind2="1"><subfield code="c">2020</subfield></datafield><datafield tag="336" ind1=" " ind2=" "><subfield code="a">nicht spezifiziert</subfield><subfield code="b">zzz</subfield><subfield code="2">rdacontent</subfield></datafield><datafield tag="337" ind1=" " ind2=" "><subfield code="a">Computermedien</subfield><subfield code="b">c</subfield><subfield code="2">rdamedia</subfield></datafield><datafield tag="338" ind1=" " ind2=" "><subfield code="a">Online-Ressource</subfield><subfield code="b">cr</subfield><subfield code="2">rdacarrier</subfield></datafield><datafield tag="520" ind1=" " ind2=" "><subfield code="a">Background: Left ventricular assist device (LVAD) implantation may be an attractive alternative therapeutic option for elderly patients with heart failure who are ineligible for heart transplantation.Aim: We aimed to describe the characteristics and outcomes of elderly patients (i.e. aged≥70 years) receiving an LVAD.Methods: This observational study was conducted in 19 centres between 2006 and 2016. Patients were divided into two groups–younger (aged<70 years) and elderly (aged≥70 years), based on age at time of LVAD implantation.Results: A total of 652 patients were included in the final analysis, and 74 patients (11.3%) were aged≥70 years at the time of LVAD implantation (maximal age 77.6 years). The proportion of elderly patients receiving an LVAD each year was constant, with a median of 10.6% (interquartile range 8.0–15.4%) per year, and all were implanted as destination therapy. Elderly and younger patients had similar durations of hospitalization in intensive care units and total lengths of hospital stays. Both age groups experienced similar rates of LVAD-related complications (i.e. stroke, bleeding, driveline infection and LVAD exchange), and the occurrence of LVAD complications did not impact survival in the elderly group compared with the younger group. 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|
| author |
Galand, Vincent |
| spellingShingle |
Galand, Vincent ddc 610 bkl 44.85 misc Left ventricular assist device misc Elderly patients misc Septuagenarians misc Survival misc LVAD-related complications Septuagenarian population has similar survival and outcomes to younger patients after left ventricular assist device implantation |
| authorStr |
Galand, Vincent |
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@@773@@(DE-627)568486064 |
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electronic Article |
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610 - Medicine & health |
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610 DE-600 44.85 bkl Septuagenarian population has similar survival and outcomes to younger patients after left ventricular assist device implantation Left ventricular assist device Elderly patients Septuagenarians Survival LVAD-related complications |
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Septuagenarian population has similar survival and outcomes to younger patients after left ventricular assist device implantation |
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Septuagenarian population has similar survival and outcomes to younger patients after left ventricular assist device implantation |
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Galand, Vincent Flécher, Erwan Chabanne, Céline Lelong, Bernard Goéminne, Céline Vincentelli, André Delmas, Clément Dambrin, Camille Nubret, Karine Pernot, Mathieu Kindo, Michel Hoang Minh, Tam Gaudard, Philippe Frapier, Jean Marc Michel, Magali Sénage, Thomas Boignard, Aude Chavanon, Olivier Verdonk, Constance Para, Marylou Pelcé, Edeline Gariboldi, Vlad Pozzi, Matteo Obadia, Jean-François Litlzer, Pierre Yves Anselme, Frédéric Babatasi, Gerard Plane, Anne Flore Garnier, Fabien Bielefeld, Marie Hamon, David Radu, Costin Bourguignon, Thierry Genet, Thibaud Eschalier, Romain D’Ostrevy, Nicolas Bories, Marie-Cécile Marijon, Eloi Vanhuyse, Fabrice Blangy, Hugues Leclercq, Christophe Martins, Raphaël P. |
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10.1016/j.acvd.2020.05.018 |
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septuagenarian population has similar survival and outcomes to younger patients after left ventricular assist device implantation |
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Septuagenarian population has similar survival and outcomes to younger patients after left ventricular assist device implantation |
| abstract |
Background: Left ventricular assist device (LVAD) implantation may be an attractive alternative therapeutic option for elderly patients with heart failure who are ineligible for heart transplantation.Aim: We aimed to describe the characteristics and outcomes of elderly patients (i.e. aged≥70 years) receiving an LVAD.Methods: This observational study was conducted in 19 centres between 2006 and 2016. Patients were divided into two groups–younger (aged<70 years) and elderly (aged≥70 years), based on age at time of LVAD implantation.Results: A total of 652 patients were included in the final analysis, and 74 patients (11.3%) were aged≥70 years at the time of LVAD implantation (maximal age 77.6 years). The proportion of elderly patients receiving an LVAD each year was constant, with a median of 10.6% (interquartile range 8.0–15.4%) per year, and all were implanted as destination therapy. Elderly and younger patients had similar durations of hospitalization in intensive care units and total lengths of hospital stays. Both age groups experienced similar rates of LVAD-related complications (i.e. stroke, bleeding, driveline infection and LVAD exchange), and the occurrence of LVAD complications did not impact survival in the elderly group compared with the younger group. Lastly, when compared with younger patients implanted as destination therapy, the elderly group also exhibited similar mid-term survival.Conclusion: This work strongly suggests that selected elderly adults can be scheduled for LVAD implantation. |
| abstractGer |
Background: Left ventricular assist device (LVAD) implantation may be an attractive alternative therapeutic option for elderly patients with heart failure who are ineligible for heart transplantation.Aim: We aimed to describe the characteristics and outcomes of elderly patients (i.e. aged≥70 years) receiving an LVAD.Methods: This observational study was conducted in 19 centres between 2006 and 2016. Patients were divided into two groups–younger (aged<70 years) and elderly (aged≥70 years), based on age at time of LVAD implantation.Results: A total of 652 patients were included in the final analysis, and 74 patients (11.3%) were aged≥70 years at the time of LVAD implantation (maximal age 77.6 years). The proportion of elderly patients receiving an LVAD each year was constant, with a median of 10.6% (interquartile range 8.0–15.4%) per year, and all were implanted as destination therapy. Elderly and younger patients had similar durations of hospitalization in intensive care units and total lengths of hospital stays. Both age groups experienced similar rates of LVAD-related complications (i.e. stroke, bleeding, driveline infection and LVAD exchange), and the occurrence of LVAD complications did not impact survival in the elderly group compared with the younger group. Lastly, when compared with younger patients implanted as destination therapy, the elderly group also exhibited similar mid-term survival.Conclusion: This work strongly suggests that selected elderly adults can be scheduled for LVAD implantation. |
| abstract_unstemmed |
Background: Left ventricular assist device (LVAD) implantation may be an attractive alternative therapeutic option for elderly patients with heart failure who are ineligible for heart transplantation.Aim: We aimed to describe the characteristics and outcomes of elderly patients (i.e. aged≥70 years) receiving an LVAD.Methods: This observational study was conducted in 19 centres between 2006 and 2016. Patients were divided into two groups–younger (aged<70 years) and elderly (aged≥70 years), based on age at time of LVAD implantation.Results: A total of 652 patients were included in the final analysis, and 74 patients (11.3%) were aged≥70 years at the time of LVAD implantation (maximal age 77.6 years). The proportion of elderly patients receiving an LVAD each year was constant, with a median of 10.6% (interquartile range 8.0–15.4%) per year, and all were implanted as destination therapy. Elderly and younger patients had similar durations of hospitalization in intensive care units and total lengths of hospital stays. Both age groups experienced similar rates of LVAD-related complications (i.e. stroke, bleeding, driveline infection and LVAD exchange), and the occurrence of LVAD complications did not impact survival in the elderly group compared with the younger group. Lastly, when compared with younger patients implanted as destination therapy, the elderly group also exhibited similar mid-term survival.Conclusion: This work strongly suggests that selected elderly adults can be scheduled for LVAD implantation. |
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Septuagenarian population has similar survival and outcomes to younger patients after left ventricular assist device implantation |
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Flécher, Erwan Chabanne, Céline Lelong, Bernard Goéminne, Céline Vincentelli, André Delmas, Clément Dambrin, Camille Nubret, Karine Pernot, Mathieu Kindo, Michel Hoang Minh, Tam Gaudard, Philippe Frapier, Jean Marc Michel, Magali Sénage, Thomas Boignard, Aude Chavanon, Olivier Verdonk, Constance Para, Marylou Pelcé, Edeline Gariboldi, Vlad Pozzi, Matteo Obadia, Jean-François Litlzer, Pierre Yves Anselme, Frédéric Babatasi, Gerard Plane, Anne Flore Garnier, Fabien Bielefeld, Marie Hamon, David Radu, Costin Bourguignon, Thierry Genet, Thibaud Eschalier, Romain D’Ostrevy, Nicolas Bories, Marie-Cécile Marijon, Eloi Vanhuyse, Fabrice Blangy, Hugues Leclercq, Christophe Martins, Raphaël P. |
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