Microneedle-assisted technology for minimally invasive medical sensing

In recent years, applications of microneedle (MN) technology in medical health sensing devices and platforms have been developed due to its advantages of minimal invasiveness, real-time, and convenience. Electrochemical biosensors and interstitial fluid (ISF) direct extraction are two types of MN ba...
Ausführliche Beschreibung

Gespeichert in:

Autor*in:	Zhang, Bao Li [verfasserIn] Zhang, Xiao Peng [verfasserIn] Chen, Bo Zhi [verfasserIn] Fei, Wen Min [verfasserIn] Cui, Yong [verfasserIn] Guo, Xin Dong [verfasserIn]

Format:	E-Artikel
Sprache:	Englisch

Erschienen:	2020

Schlagwörter:	Microneedle Medical sensing Electrochemical sensors ISF direct extraction

Übergeordnetes Werk:	Enthalten in: Microchemical journal - Orlando, Fla. : Academic Press, 1957, 162
Übergeordnetes Werk:	volume:162

DOI / URN:	10.1016/j.microc.2020.105830

Katalog-ID:	ELV005384516

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520			\|a In recent years, applications of microneedle (MN) technology in medical health sensing devices and platforms have been developed due to its advantages of minimal invasiveness, real-time, and convenience. Electrochemical biosensors and interstitial fluid (ISF) direct extraction are two types of MN based technologies applied in medical sensing. In MN based electrochemical biosensors, conducting polymers (CPs), enzymes, nanoparticles, and their composites are used to modify MN electrodes to selectively monitor glucose, lactate, alcohol, urea, amino acids, therapeutic drugs, or bio-signals recording. In MN based ISF direct extraction for further sensing, silicon, silicon oxide, and some polymers are introduced to the fabrication of hollow or hydrogel MNs. These two types of MN based technologies were employed in glucose monitoring, therapeutic drug monitoring (TDM), protein analysis, etc. This review is to present the development and application of MN based technologies on electrochemical biosensors and ISF direct extraction and also to describe some prospects and limitations on medical sensing.
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700	1		\|a Cui, Yong \|e verfasserin \|4 aut
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allfields	10.1016/j.microc.2020.105830 doi (DE-627)ELV005384516 (ELSEVIER)S0026-265X(20)33772-3 DE-627 ger DE-627 rda eng 540 DE-600 35.00 bkl Zhang, Bao Li verfasserin aut Microneedle-assisted technology for minimally invasive medical sensing 2020 nicht spezifiziert zzz rdacontent Computermedien c rdamedia Online-Ressource cr rdacarrier In recent years, applications of microneedle (MN) technology in medical health sensing devices and platforms have been developed due to its advantages of minimal invasiveness, real-time, and convenience. Electrochemical biosensors and interstitial fluid (ISF) direct extraction are two types of MN based technologies applied in medical sensing. In MN based electrochemical biosensors, conducting polymers (CPs), enzymes, nanoparticles, and their composites are used to modify MN electrodes to selectively monitor glucose, lactate, alcohol, urea, amino acids, therapeutic drugs, or bio-signals recording. In MN based ISF direct extraction for further sensing, silicon, silicon oxide, and some polymers are introduced to the fabrication of hollow or hydrogel MNs. These two types of MN based technologies were employed in glucose monitoring, therapeutic drug monitoring (TDM), protein analysis, etc. This review is to present the development and application of MN based technologies on electrochemical biosensors and ISF direct extraction and also to describe some prospects and limitations on medical sensing. Microneedle Medical sensing Electrochemical sensors ISF direct extraction Zhang, Xiao Peng verfasserin aut Chen, Bo Zhi verfasserin aut Fei, Wen Min verfasserin aut Cui, Yong verfasserin aut Guo, Xin Dong verfasserin aut Enthalten in Microchemical journal Orlando, Fla. : Academic Press, 1957 162 Online-Ressource (DE-627)267840217 (DE-600)1471165-5 (DE-576)259483729 1095-9149 nnns volume:162 GBV_USEFLAG_U SYSFLAG_U GBV_ELV SSG-OLC-PHA GBV_ILN_20 GBV_ILN_22 GBV_ILN_23 GBV_ILN_24 GBV_ILN_31 GBV_ILN_32 GBV_ILN_40 GBV_ILN_60 GBV_ILN_62 GBV_ILN_63 GBV_ILN_65 GBV_ILN_69 GBV_ILN_70 GBV_ILN_73 GBV_ILN_74 GBV_ILN_90 GBV_ILN_95 GBV_ILN_100 GBV_ILN_101 GBV_ILN_105 GBV_ILN_110 GBV_ILN_150 GBV_ILN_151 GBV_ILN_224 GBV_ILN_370 GBV_ILN_602 GBV_ILN_702 GBV_ILN_2003 GBV_ILN_2004 GBV_ILN_2005 GBV_ILN_2011 GBV_ILN_2014 GBV_ILN_2015 GBV_ILN_2020 GBV_ILN_2021 GBV_ILN_2025 GBV_ILN_2027 GBV_ILN_2034 GBV_ILN_2038 GBV_ILN_2044 GBV_ILN_2048 GBV_ILN_2049 GBV_ILN_2050 GBV_ILN_2056 GBV_ILN_2059 GBV_ILN_2061 GBV_ILN_2064 GBV_ILN_2065 GBV_ILN_2068 GBV_ILN_2111 GBV_ILN_2112 GBV_ILN_2113 GBV_ILN_2118 GBV_ILN_2122 GBV_ILN_2129 GBV_ILN_2143 GBV_ILN_2147 GBV_ILN_2148 GBV_ILN_2152 GBV_ILN_2153 GBV_ILN_2190 GBV_ILN_2336 GBV_ILN_2507 GBV_ILN_2522 GBV_ILN_4035 GBV_ILN_4037 GBV_ILN_4112 GBV_ILN_4125 GBV_ILN_4126 GBV_ILN_4242 GBV_ILN_4251 GBV_ILN_4305 GBV_ILN_4313 GBV_ILN_4323 GBV_ILN_4324 GBV_ILN_4325 GBV_ILN_4326 GBV_ILN_4333 GBV_ILN_4334 GBV_ILN_4335 GBV_ILN_4338 GBV_ILN_4393 35.00 Chemie: Allgemeines AR 162
spelling	10.1016/j.microc.2020.105830 doi (DE-627)ELV005384516 (ELSEVIER)S0026-265X(20)33772-3 DE-627 ger DE-627 rda eng 540 DE-600 35.00 bkl Zhang, Bao Li verfasserin aut Microneedle-assisted technology for minimally invasive medical sensing 2020 nicht spezifiziert zzz rdacontent Computermedien c rdamedia Online-Ressource cr rdacarrier In recent years, applications of microneedle (MN) technology in medical health sensing devices and platforms have been developed due to its advantages of minimal invasiveness, real-time, and convenience. Electrochemical biosensors and interstitial fluid (ISF) direct extraction are two types of MN based technologies applied in medical sensing. In MN based electrochemical biosensors, conducting polymers (CPs), enzymes, nanoparticles, and their composites are used to modify MN electrodes to selectively monitor glucose, lactate, alcohol, urea, amino acids, therapeutic drugs, or bio-signals recording. In MN based ISF direct extraction for further sensing, silicon, silicon oxide, and some polymers are introduced to the fabrication of hollow or hydrogel MNs. These two types of MN based technologies were employed in glucose monitoring, therapeutic drug monitoring (TDM), protein analysis, etc. This review is to present the development and application of MN based technologies on electrochemical biosensors and ISF direct extraction and also to describe some prospects and limitations on medical sensing. Microneedle Medical sensing Electrochemical sensors ISF direct extraction Zhang, Xiao Peng verfasserin aut Chen, Bo Zhi verfasserin aut Fei, Wen Min verfasserin aut Cui, Yong verfasserin aut Guo, Xin Dong verfasserin aut Enthalten in Microchemical journal Orlando, Fla. : Academic Press, 1957 162 Online-Ressource (DE-627)267840217 (DE-600)1471165-5 (DE-576)259483729 1095-9149 nnns volume:162 GBV_USEFLAG_U SYSFLAG_U GBV_ELV SSG-OLC-PHA GBV_ILN_20 GBV_ILN_22 GBV_ILN_23 GBV_ILN_24 GBV_ILN_31 GBV_ILN_32 GBV_ILN_40 GBV_ILN_60 GBV_ILN_62 GBV_ILN_63 GBV_ILN_65 GBV_ILN_69 GBV_ILN_70 GBV_ILN_73 GBV_ILN_74 GBV_ILN_90 GBV_ILN_95 GBV_ILN_100 GBV_ILN_101 GBV_ILN_105 GBV_ILN_110 GBV_ILN_150 GBV_ILN_151 GBV_ILN_224 GBV_ILN_370 GBV_ILN_602 GBV_ILN_702 GBV_ILN_2003 GBV_ILN_2004 GBV_ILN_2005 GBV_ILN_2011 GBV_ILN_2014 GBV_ILN_2015 GBV_ILN_2020 GBV_ILN_2021 GBV_ILN_2025 GBV_ILN_2027 GBV_ILN_2034 GBV_ILN_2038 GBV_ILN_2044 GBV_ILN_2048 GBV_ILN_2049 GBV_ILN_2050 GBV_ILN_2056 GBV_ILN_2059 GBV_ILN_2061 GBV_ILN_2064 GBV_ILN_2065 GBV_ILN_2068 GBV_ILN_2111 GBV_ILN_2112 GBV_ILN_2113 GBV_ILN_2118 GBV_ILN_2122 GBV_ILN_2129 GBV_ILN_2143 GBV_ILN_2147 GBV_ILN_2148 GBV_ILN_2152 GBV_ILN_2153 GBV_ILN_2190 GBV_ILN_2336 GBV_ILN_2507 GBV_ILN_2522 GBV_ILN_4035 GBV_ILN_4037 GBV_ILN_4112 GBV_ILN_4125 GBV_ILN_4126 GBV_ILN_4242 GBV_ILN_4251 GBV_ILN_4305 GBV_ILN_4313 GBV_ILN_4323 GBV_ILN_4324 GBV_ILN_4325 GBV_ILN_4326 GBV_ILN_4333 GBV_ILN_4334 GBV_ILN_4335 GBV_ILN_4338 GBV_ILN_4393 35.00 Chemie: Allgemeines AR 162
allfields_unstemmed	10.1016/j.microc.2020.105830 doi (DE-627)ELV005384516 (ELSEVIER)S0026-265X(20)33772-3 DE-627 ger DE-627 rda eng 540 DE-600 35.00 bkl Zhang, Bao Li verfasserin aut Microneedle-assisted technology for minimally invasive medical sensing 2020 nicht spezifiziert zzz rdacontent Computermedien c rdamedia Online-Ressource cr rdacarrier In recent years, applications of microneedle (MN) technology in medical health sensing devices and platforms have been developed due to its advantages of minimal invasiveness, real-time, and convenience. Electrochemical biosensors and interstitial fluid (ISF) direct extraction are two types of MN based technologies applied in medical sensing. In MN based electrochemical biosensors, conducting polymers (CPs), enzymes, nanoparticles, and their composites are used to modify MN electrodes to selectively monitor glucose, lactate, alcohol, urea, amino acids, therapeutic drugs, or bio-signals recording. In MN based ISF direct extraction for further sensing, silicon, silicon oxide, and some polymers are introduced to the fabrication of hollow or hydrogel MNs. These two types of MN based technologies were employed in glucose monitoring, therapeutic drug monitoring (TDM), protein analysis, etc. This review is to present the development and application of MN based technologies on electrochemical biosensors and ISF direct extraction and also to describe some prospects and limitations on medical sensing. Microneedle Medical sensing Electrochemical sensors ISF direct extraction Zhang, Xiao Peng verfasserin aut Chen, Bo Zhi verfasserin aut Fei, Wen Min verfasserin aut Cui, Yong verfasserin aut Guo, Xin Dong verfasserin aut Enthalten in Microchemical journal Orlando, Fla. : Academic Press, 1957 162 Online-Ressource (DE-627)267840217 (DE-600)1471165-5 (DE-576)259483729 1095-9149 nnns volume:162 GBV_USEFLAG_U SYSFLAG_U GBV_ELV SSG-OLC-PHA GBV_ILN_20 GBV_ILN_22 GBV_ILN_23 GBV_ILN_24 GBV_ILN_31 GBV_ILN_32 GBV_ILN_40 GBV_ILN_60 GBV_ILN_62 GBV_ILN_63 GBV_ILN_65 GBV_ILN_69 GBV_ILN_70 GBV_ILN_73 GBV_ILN_74 GBV_ILN_90 GBV_ILN_95 GBV_ILN_100 GBV_ILN_101 GBV_ILN_105 GBV_ILN_110 GBV_ILN_150 GBV_ILN_151 GBV_ILN_224 GBV_ILN_370 GBV_ILN_602 GBV_ILN_702 GBV_ILN_2003 GBV_ILN_2004 GBV_ILN_2005 GBV_ILN_2011 GBV_ILN_2014 GBV_ILN_2015 GBV_ILN_2020 GBV_ILN_2021 GBV_ILN_2025 GBV_ILN_2027 GBV_ILN_2034 GBV_ILN_2038 GBV_ILN_2044 GBV_ILN_2048 GBV_ILN_2049 GBV_ILN_2050 GBV_ILN_2056 GBV_ILN_2059 GBV_ILN_2061 GBV_ILN_2064 GBV_ILN_2065 GBV_ILN_2068 GBV_ILN_2111 GBV_ILN_2112 GBV_ILN_2113 GBV_ILN_2118 GBV_ILN_2122 GBV_ILN_2129 GBV_ILN_2143 GBV_ILN_2147 GBV_ILN_2148 GBV_ILN_2152 GBV_ILN_2153 GBV_ILN_2190 GBV_ILN_2336 GBV_ILN_2507 GBV_ILN_2522 GBV_ILN_4035 GBV_ILN_4037 GBV_ILN_4112 GBV_ILN_4125 GBV_ILN_4126 GBV_ILN_4242 GBV_ILN_4251 GBV_ILN_4305 GBV_ILN_4313 GBV_ILN_4323 GBV_ILN_4324 GBV_ILN_4325 GBV_ILN_4326 GBV_ILN_4333 GBV_ILN_4334 GBV_ILN_4335 GBV_ILN_4338 GBV_ILN_4393 35.00 Chemie: Allgemeines AR 162
allfieldsGer	10.1016/j.microc.2020.105830 doi (DE-627)ELV005384516 (ELSEVIER)S0026-265X(20)33772-3 DE-627 ger DE-627 rda eng 540 DE-600 35.00 bkl Zhang, Bao Li verfasserin aut Microneedle-assisted technology for minimally invasive medical sensing 2020 nicht spezifiziert zzz rdacontent Computermedien c rdamedia Online-Ressource cr rdacarrier In recent years, applications of microneedle (MN) technology in medical health sensing devices and platforms have been developed due to its advantages of minimal invasiveness, real-time, and convenience. Electrochemical biosensors and interstitial fluid (ISF) direct extraction are two types of MN based technologies applied in medical sensing. In MN based electrochemical biosensors, conducting polymers (CPs), enzymes, nanoparticles, and their composites are used to modify MN electrodes to selectively monitor glucose, lactate, alcohol, urea, amino acids, therapeutic drugs, or bio-signals recording. In MN based ISF direct extraction for further sensing, silicon, silicon oxide, and some polymers are introduced to the fabrication of hollow or hydrogel MNs. These two types of MN based technologies were employed in glucose monitoring, therapeutic drug monitoring (TDM), protein analysis, etc. This review is to present the development and application of MN based technologies on electrochemical biosensors and ISF direct extraction and also to describe some prospects and limitations on medical sensing. Microneedle Medical sensing Electrochemical sensors ISF direct extraction Zhang, Xiao Peng verfasserin aut Chen, Bo Zhi verfasserin aut Fei, Wen Min verfasserin aut Cui, Yong verfasserin aut Guo, Xin Dong verfasserin aut Enthalten in Microchemical journal Orlando, Fla. : Academic Press, 1957 162 Online-Ressource (DE-627)267840217 (DE-600)1471165-5 (DE-576)259483729 1095-9149 nnns volume:162 GBV_USEFLAG_U SYSFLAG_U GBV_ELV SSG-OLC-PHA GBV_ILN_20 GBV_ILN_22 GBV_ILN_23 GBV_ILN_24 GBV_ILN_31 GBV_ILN_32 GBV_ILN_40 GBV_ILN_60 GBV_ILN_62 GBV_ILN_63 GBV_ILN_65 GBV_ILN_69 GBV_ILN_70 GBV_ILN_73 GBV_ILN_74 GBV_ILN_90 GBV_ILN_95 GBV_ILN_100 GBV_ILN_101 GBV_ILN_105 GBV_ILN_110 GBV_ILN_150 GBV_ILN_151 GBV_ILN_224 GBV_ILN_370 GBV_ILN_602 GBV_ILN_702 GBV_ILN_2003 GBV_ILN_2004 GBV_ILN_2005 GBV_ILN_2011 GBV_ILN_2014 GBV_ILN_2015 GBV_ILN_2020 GBV_ILN_2021 GBV_ILN_2025 GBV_ILN_2027 GBV_ILN_2034 GBV_ILN_2038 GBV_ILN_2044 GBV_ILN_2048 GBV_ILN_2049 GBV_ILN_2050 GBV_ILN_2056 GBV_ILN_2059 GBV_ILN_2061 GBV_ILN_2064 GBV_ILN_2065 GBV_ILN_2068 GBV_ILN_2111 GBV_ILN_2112 GBV_ILN_2113 GBV_ILN_2118 GBV_ILN_2122 GBV_ILN_2129 GBV_ILN_2143 GBV_ILN_2147 GBV_ILN_2148 GBV_ILN_2152 GBV_ILN_2153 GBV_ILN_2190 GBV_ILN_2336 GBV_ILN_2507 GBV_ILN_2522 GBV_ILN_4035 GBV_ILN_4037 GBV_ILN_4112 GBV_ILN_4125 GBV_ILN_4126 GBV_ILN_4242 GBV_ILN_4251 GBV_ILN_4305 GBV_ILN_4313 GBV_ILN_4323 GBV_ILN_4324 GBV_ILN_4325 GBV_ILN_4326 GBV_ILN_4333 GBV_ILN_4334 GBV_ILN_4335 GBV_ILN_4338 GBV_ILN_4393 35.00 Chemie: Allgemeines AR 162
allfieldsSound	10.1016/j.microc.2020.105830 doi (DE-627)ELV005384516 (ELSEVIER)S0026-265X(20)33772-3 DE-627 ger DE-627 rda eng 540 DE-600 35.00 bkl Zhang, Bao Li verfasserin aut Microneedle-assisted technology for minimally invasive medical sensing 2020 nicht spezifiziert zzz rdacontent Computermedien c rdamedia Online-Ressource cr rdacarrier In recent years, applications of microneedle (MN) technology in medical health sensing devices and platforms have been developed due to its advantages of minimal invasiveness, real-time, and convenience. Electrochemical biosensors and interstitial fluid (ISF) direct extraction are two types of MN based technologies applied in medical sensing. In MN based electrochemical biosensors, conducting polymers (CPs), enzymes, nanoparticles, and their composites are used to modify MN electrodes to selectively monitor glucose, lactate, alcohol, urea, amino acids, therapeutic drugs, or bio-signals recording. In MN based ISF direct extraction for further sensing, silicon, silicon oxide, and some polymers are introduced to the fabrication of hollow or hydrogel MNs. These two types of MN based technologies were employed in glucose monitoring, therapeutic drug monitoring (TDM), protein analysis, etc. This review is to present the development and application of MN based technologies on electrochemical biosensors and ISF direct extraction and also to describe some prospects and limitations on medical sensing. Microneedle Medical sensing Electrochemical sensors ISF direct extraction Zhang, Xiao Peng verfasserin aut Chen, Bo Zhi verfasserin aut Fei, Wen Min verfasserin aut Cui, Yong verfasserin aut Guo, Xin Dong verfasserin aut Enthalten in Microchemical journal Orlando, Fla. : Academic Press, 1957 162 Online-Ressource (DE-627)267840217 (DE-600)1471165-5 (DE-576)259483729 1095-9149 nnns volume:162 GBV_USEFLAG_U SYSFLAG_U GBV_ELV SSG-OLC-PHA GBV_ILN_20 GBV_ILN_22 GBV_ILN_23 GBV_ILN_24 GBV_ILN_31 GBV_ILN_32 GBV_ILN_40 GBV_ILN_60 GBV_ILN_62 GBV_ILN_63 GBV_ILN_65 GBV_ILN_69 GBV_ILN_70 GBV_ILN_73 GBV_ILN_74 GBV_ILN_90 GBV_ILN_95 GBV_ILN_100 GBV_ILN_101 GBV_ILN_105 GBV_ILN_110 GBV_ILN_150 GBV_ILN_151 GBV_ILN_224 GBV_ILN_370 GBV_ILN_602 GBV_ILN_702 GBV_ILN_2003 GBV_ILN_2004 GBV_ILN_2005 GBV_ILN_2011 GBV_ILN_2014 GBV_ILN_2015 GBV_ILN_2020 GBV_ILN_2021 GBV_ILN_2025 GBV_ILN_2027 GBV_ILN_2034 GBV_ILN_2038 GBV_ILN_2044 GBV_ILN_2048 GBV_ILN_2049 GBV_ILN_2050 GBV_ILN_2056 GBV_ILN_2059 GBV_ILN_2061 GBV_ILN_2064 GBV_ILN_2065 GBV_ILN_2068 GBV_ILN_2111 GBV_ILN_2112 GBV_ILN_2113 GBV_ILN_2118 GBV_ILN_2122 GBV_ILN_2129 GBV_ILN_2143 GBV_ILN_2147 GBV_ILN_2148 GBV_ILN_2152 GBV_ILN_2153 GBV_ILN_2190 GBV_ILN_2336 GBV_ILN_2507 GBV_ILN_2522 GBV_ILN_4035 GBV_ILN_4037 GBV_ILN_4112 GBV_ILN_4125 GBV_ILN_4126 GBV_ILN_4242 GBV_ILN_4251 GBV_ILN_4305 GBV_ILN_4313 GBV_ILN_4323 GBV_ILN_4324 GBV_ILN_4325 GBV_ILN_4326 GBV_ILN_4333 GBV_ILN_4334 GBV_ILN_4335 GBV_ILN_4338 GBV_ILN_4393 35.00 Chemie: Allgemeines AR 162
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title	Microneedle-assisted technology for minimally invasive medical sensing
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title_sort	microneedle-assisted technology for minimally invasive medical sensing
title_auth	Microneedle-assisted technology for minimally invasive medical sensing
abstract	In recent years, applications of microneedle (MN) technology in medical health sensing devices and platforms have been developed due to its advantages of minimal invasiveness, real-time, and convenience. Electrochemical biosensors and interstitial fluid (ISF) direct extraction are two types of MN based technologies applied in medical sensing. In MN based electrochemical biosensors, conducting polymers (CPs), enzymes, nanoparticles, and their composites are used to modify MN electrodes to selectively monitor glucose, lactate, alcohol, urea, amino acids, therapeutic drugs, or bio-signals recording. In MN based ISF direct extraction for further sensing, silicon, silicon oxide, and some polymers are introduced to the fabrication of hollow or hydrogel MNs. These two types of MN based technologies were employed in glucose monitoring, therapeutic drug monitoring (TDM), protein analysis, etc. This review is to present the development and application of MN based technologies on electrochemical biosensors and ISF direct extraction and also to describe some prospects and limitations on medical sensing.
abstractGer	In recent years, applications of microneedle (MN) technology in medical health sensing devices and platforms have been developed due to its advantages of minimal invasiveness, real-time, and convenience. Electrochemical biosensors and interstitial fluid (ISF) direct extraction are two types of MN based technologies applied in medical sensing. In MN based electrochemical biosensors, conducting polymers (CPs), enzymes, nanoparticles, and their composites are used to modify MN electrodes to selectively monitor glucose, lactate, alcohol, urea, amino acids, therapeutic drugs, or bio-signals recording. In MN based ISF direct extraction for further sensing, silicon, silicon oxide, and some polymers are introduced to the fabrication of hollow or hydrogel MNs. These two types of MN based technologies were employed in glucose monitoring, therapeutic drug monitoring (TDM), protein analysis, etc. This review is to present the development and application of MN based technologies on electrochemical biosensors and ISF direct extraction and also to describe some prospects and limitations on medical sensing.
abstract_unstemmed	In recent years, applications of microneedle (MN) technology in medical health sensing devices and platforms have been developed due to its advantages of minimal invasiveness, real-time, and convenience. Electrochemical biosensors and interstitial fluid (ISF) direct extraction are two types of MN based technologies applied in medical sensing. In MN based electrochemical biosensors, conducting polymers (CPs), enzymes, nanoparticles, and their composites are used to modify MN electrodes to selectively monitor glucose, lactate, alcohol, urea, amino acids, therapeutic drugs, or bio-signals recording. In MN based ISF direct extraction for further sensing, silicon, silicon oxide, and some polymers are introduced to the fabrication of hollow or hydrogel MNs. These two types of MN based technologies were employed in glucose monitoring, therapeutic drug monitoring (TDM), protein analysis, etc. This review is to present the development and application of MN based technologies on electrochemical biosensors and ISF direct extraction and also to describe some prospects and limitations on medical sensing.
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title_short	Microneedle-assisted technology for minimally invasive medical sensing
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author2	Zhang, Xiao Peng Chen, Bo Zhi Fei, Wen Min Cui, Yong Guo, Xin Dong
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up_date	2024-07-06T17:47:25.975Z
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