Synthesis and supramolecular arrangement of new stearoyl acid-based phenalenone derivatives
Lipid-based photoantimicrobial supramolecular assemblies are promising structures for the development of new photodynamic treatments of wound bacterial infections. Phenalenone (1H-phenalene-1-one, PN) has been used to obtain four stearoyl acid-based phenalenone derivatives (PNC18), with different ty...
Ausführliche Beschreibung
Autor*in: |
Godard, Jérémy [verfasserIn] Chapron, David [verfasserIn] Bregier, Frédérique [verfasserIn] Rosilio, Véronique [verfasserIn] Sol, Vincent [verfasserIn] |
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E-Artikel |
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Sprache: |
Englisch |
Erschienen: |
2020 |
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Schlagwörter: |
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Übergeordnetes Werk: |
Enthalten in: Colloids and surfaces / A - Amsterdam [u.a.] : Elsevier Science, 1993, 612 |
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Übergeordnetes Werk: |
volume:612 |
DOI / URN: |
10.1016/j.colsurfa.2020.125988 |
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Katalog-ID: |
ELV005455162 |
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245 | 1 | 0 | |a Synthesis and supramolecular arrangement of new stearoyl acid-based phenalenone derivatives |
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520 | |a Lipid-based photoantimicrobial supramolecular assemblies are promising structures for the development of new photodynamic treatments of wound bacterial infections. Phenalenone (1H-phenalene-1-one, PN) has been used to obtain four stearoyl acid-based phenalenone derivatives (PNC18), with different types of linkage and different number of acyl chains. After studying the interfacial properties of these compounds, nano-objects were formed with either pure PNC18 or mixtures of PNC18 with 1-stearoyl-2-oleoyl-sn-glycero-3-phosphocholine. Morphologies of these nano-objects were analyzed by CryoTEM imaging. The distearoyl glycerol PN derivative appears promising for building photosensitive micelles or vesicles. | ||
650 | 4 | |a Phenalenone-stearoyl acid conjugate | |
650 | 4 | |a Micelles | |
650 | 4 | |a Vesicles | |
650 | 4 | |a Supramolecular chemistry | |
650 | 4 | |a Self-assembly | |
650 | 4 | |a CryoTem imaging | |
700 | 1 | |a Chapron, David |e verfasserin |4 aut | |
700 | 1 | |a Bregier, Frédérique |e verfasserin |4 aut | |
700 | 1 | |a Rosilio, Véronique |e verfasserin |4 aut | |
700 | 1 | |a Sol, Vincent |e verfasserin |4 aut | |
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allfields |
10.1016/j.colsurfa.2020.125988 doi (DE-627)ELV005455162 (ELSEVIER)S0927-7757(20)31581-8 DE-627 ger DE-627 rda eng 540 DE-600 35.18 bkl 33.68 bkl 52.78 bkl 58.20 bkl Godard, Jérémy verfasserin aut Synthesis and supramolecular arrangement of new stearoyl acid-based phenalenone derivatives 2020 nicht spezifiziert zzz rdacontent Computermedien c rdamedia Online-Ressource cr rdacarrier Lipid-based photoantimicrobial supramolecular assemblies are promising structures for the development of new photodynamic treatments of wound bacterial infections. Phenalenone (1H-phenalene-1-one, PN) has been used to obtain four stearoyl acid-based phenalenone derivatives (PNC18), with different types of linkage and different number of acyl chains. After studying the interfacial properties of these compounds, nano-objects were formed with either pure PNC18 or mixtures of PNC18 with 1-stearoyl-2-oleoyl-sn-glycero-3-phosphocholine. Morphologies of these nano-objects were analyzed by CryoTEM imaging. The distearoyl glycerol PN derivative appears promising for building photosensitive micelles or vesicles. Phenalenone-stearoyl acid conjugate Micelles Vesicles Supramolecular chemistry Self-assembly CryoTem imaging Chapron, David verfasserin aut Bregier, Frédérique verfasserin aut Rosilio, Véronique verfasserin aut Sol, Vincent verfasserin aut Enthalten in Colloids and surfaces / A Amsterdam [u.a.] : Elsevier Science, 1993 612 Online-Ressource (DE-627)306659956 (DE-600)1500517-3 (DE-576)098614843 1873-4359 nnns volume:612 GBV_USEFLAG_U SYSFLAG_U GBV_ELV SSG-OLC-PHA GBV_ILN_20 GBV_ILN_22 GBV_ILN_23 GBV_ILN_24 GBV_ILN_31 GBV_ILN_32 GBV_ILN_40 GBV_ILN_60 GBV_ILN_62 GBV_ILN_63 GBV_ILN_65 GBV_ILN_69 GBV_ILN_70 GBV_ILN_73 GBV_ILN_74 GBV_ILN_90 GBV_ILN_95 GBV_ILN_100 GBV_ILN_101 GBV_ILN_105 GBV_ILN_110 GBV_ILN_150 GBV_ILN_151 GBV_ILN_224 GBV_ILN_370 GBV_ILN_602 GBV_ILN_702 GBV_ILN_2003 GBV_ILN_2004 GBV_ILN_2005 GBV_ILN_2006 GBV_ILN_2008 GBV_ILN_2010 GBV_ILN_2011 GBV_ILN_2014 GBV_ILN_2015 GBV_ILN_2020 GBV_ILN_2021 GBV_ILN_2025 GBV_ILN_2027 GBV_ILN_2034 GBV_ILN_2038 GBV_ILN_2044 GBV_ILN_2048 GBV_ILN_2049 GBV_ILN_2050 GBV_ILN_2056 GBV_ILN_2059 GBV_ILN_2061 GBV_ILN_2064 GBV_ILN_2065 GBV_ILN_2068 GBV_ILN_2088 GBV_ILN_2111 GBV_ILN_2112 GBV_ILN_2113 GBV_ILN_2118 GBV_ILN_2122 GBV_ILN_2129 GBV_ILN_2143 GBV_ILN_2147 GBV_ILN_2148 GBV_ILN_2152 GBV_ILN_2153 GBV_ILN_2190 GBV_ILN_2336 GBV_ILN_2411 GBV_ILN_2470 GBV_ILN_2507 GBV_ILN_2522 GBV_ILN_4035 GBV_ILN_4037 GBV_ILN_4046 GBV_ILN_4112 GBV_ILN_4125 GBV_ILN_4126 GBV_ILN_4242 GBV_ILN_4251 GBV_ILN_4305 GBV_ILN_4313 GBV_ILN_4322 GBV_ILN_4323 GBV_ILN_4324 GBV_ILN_4326 GBV_ILN_4333 GBV_ILN_4334 GBV_ILN_4335 GBV_ILN_4338 GBV_ILN_4393 35.18 Kolloidchemie Grenzflächenchemie 33.68 Oberflächen Dünne Schichten Grenzflächen Physik 52.78 Oberflächentechnik Wärmebehandlung 58.20 Chemische Technologien: Allgemeines AR 612 |
spelling |
10.1016/j.colsurfa.2020.125988 doi (DE-627)ELV005455162 (ELSEVIER)S0927-7757(20)31581-8 DE-627 ger DE-627 rda eng 540 DE-600 35.18 bkl 33.68 bkl 52.78 bkl 58.20 bkl Godard, Jérémy verfasserin aut Synthesis and supramolecular arrangement of new stearoyl acid-based phenalenone derivatives 2020 nicht spezifiziert zzz rdacontent Computermedien c rdamedia Online-Ressource cr rdacarrier Lipid-based photoantimicrobial supramolecular assemblies are promising structures for the development of new photodynamic treatments of wound bacterial infections. Phenalenone (1H-phenalene-1-one, PN) has been used to obtain four stearoyl acid-based phenalenone derivatives (PNC18), with different types of linkage and different number of acyl chains. After studying the interfacial properties of these compounds, nano-objects were formed with either pure PNC18 or mixtures of PNC18 with 1-stearoyl-2-oleoyl-sn-glycero-3-phosphocholine. Morphologies of these nano-objects were analyzed by CryoTEM imaging. The distearoyl glycerol PN derivative appears promising for building photosensitive micelles or vesicles. Phenalenone-stearoyl acid conjugate Micelles Vesicles Supramolecular chemistry Self-assembly CryoTem imaging Chapron, David verfasserin aut Bregier, Frédérique verfasserin aut Rosilio, Véronique verfasserin aut Sol, Vincent verfasserin aut Enthalten in Colloids and surfaces / A Amsterdam [u.a.] : Elsevier Science, 1993 612 Online-Ressource (DE-627)306659956 (DE-600)1500517-3 (DE-576)098614843 1873-4359 nnns volume:612 GBV_USEFLAG_U SYSFLAG_U GBV_ELV SSG-OLC-PHA GBV_ILN_20 GBV_ILN_22 GBV_ILN_23 GBV_ILN_24 GBV_ILN_31 GBV_ILN_32 GBV_ILN_40 GBV_ILN_60 GBV_ILN_62 GBV_ILN_63 GBV_ILN_65 GBV_ILN_69 GBV_ILN_70 GBV_ILN_73 GBV_ILN_74 GBV_ILN_90 GBV_ILN_95 GBV_ILN_100 GBV_ILN_101 GBV_ILN_105 GBV_ILN_110 GBV_ILN_150 GBV_ILN_151 GBV_ILN_224 GBV_ILN_370 GBV_ILN_602 GBV_ILN_702 GBV_ILN_2003 GBV_ILN_2004 GBV_ILN_2005 GBV_ILN_2006 GBV_ILN_2008 GBV_ILN_2010 GBV_ILN_2011 GBV_ILN_2014 GBV_ILN_2015 GBV_ILN_2020 GBV_ILN_2021 GBV_ILN_2025 GBV_ILN_2027 GBV_ILN_2034 GBV_ILN_2038 GBV_ILN_2044 GBV_ILN_2048 GBV_ILN_2049 GBV_ILN_2050 GBV_ILN_2056 GBV_ILN_2059 GBV_ILN_2061 GBV_ILN_2064 GBV_ILN_2065 GBV_ILN_2068 GBV_ILN_2088 GBV_ILN_2111 GBV_ILN_2112 GBV_ILN_2113 GBV_ILN_2118 GBV_ILN_2122 GBV_ILN_2129 GBV_ILN_2143 GBV_ILN_2147 GBV_ILN_2148 GBV_ILN_2152 GBV_ILN_2153 GBV_ILN_2190 GBV_ILN_2336 GBV_ILN_2411 GBV_ILN_2470 GBV_ILN_2507 GBV_ILN_2522 GBV_ILN_4035 GBV_ILN_4037 GBV_ILN_4046 GBV_ILN_4112 GBV_ILN_4125 GBV_ILN_4126 GBV_ILN_4242 GBV_ILN_4251 GBV_ILN_4305 GBV_ILN_4313 GBV_ILN_4322 GBV_ILN_4323 GBV_ILN_4324 GBV_ILN_4326 GBV_ILN_4333 GBV_ILN_4334 GBV_ILN_4335 GBV_ILN_4338 GBV_ILN_4393 35.18 Kolloidchemie Grenzflächenchemie 33.68 Oberflächen Dünne Schichten Grenzflächen Physik 52.78 Oberflächentechnik Wärmebehandlung 58.20 Chemische Technologien: Allgemeines AR 612 |
allfields_unstemmed |
10.1016/j.colsurfa.2020.125988 doi (DE-627)ELV005455162 (ELSEVIER)S0927-7757(20)31581-8 DE-627 ger DE-627 rda eng 540 DE-600 35.18 bkl 33.68 bkl 52.78 bkl 58.20 bkl Godard, Jérémy verfasserin aut Synthesis and supramolecular arrangement of new stearoyl acid-based phenalenone derivatives 2020 nicht spezifiziert zzz rdacontent Computermedien c rdamedia Online-Ressource cr rdacarrier Lipid-based photoantimicrobial supramolecular assemblies are promising structures for the development of new photodynamic treatments of wound bacterial infections. Phenalenone (1H-phenalene-1-one, PN) has been used to obtain four stearoyl acid-based phenalenone derivatives (PNC18), with different types of linkage and different number of acyl chains. After studying the interfacial properties of these compounds, nano-objects were formed with either pure PNC18 or mixtures of PNC18 with 1-stearoyl-2-oleoyl-sn-glycero-3-phosphocholine. Morphologies of these nano-objects were analyzed by CryoTEM imaging. The distearoyl glycerol PN derivative appears promising for building photosensitive micelles or vesicles. Phenalenone-stearoyl acid conjugate Micelles Vesicles Supramolecular chemistry Self-assembly CryoTem imaging Chapron, David verfasserin aut Bregier, Frédérique verfasserin aut Rosilio, Véronique verfasserin aut Sol, Vincent verfasserin aut Enthalten in Colloids and surfaces / A Amsterdam [u.a.] : Elsevier Science, 1993 612 Online-Ressource (DE-627)306659956 (DE-600)1500517-3 (DE-576)098614843 1873-4359 nnns volume:612 GBV_USEFLAG_U SYSFLAG_U GBV_ELV SSG-OLC-PHA GBV_ILN_20 GBV_ILN_22 GBV_ILN_23 GBV_ILN_24 GBV_ILN_31 GBV_ILN_32 GBV_ILN_40 GBV_ILN_60 GBV_ILN_62 GBV_ILN_63 GBV_ILN_65 GBV_ILN_69 GBV_ILN_70 GBV_ILN_73 GBV_ILN_74 GBV_ILN_90 GBV_ILN_95 GBV_ILN_100 GBV_ILN_101 GBV_ILN_105 GBV_ILN_110 GBV_ILN_150 GBV_ILN_151 GBV_ILN_224 GBV_ILN_370 GBV_ILN_602 GBV_ILN_702 GBV_ILN_2003 GBV_ILN_2004 GBV_ILN_2005 GBV_ILN_2006 GBV_ILN_2008 GBV_ILN_2010 GBV_ILN_2011 GBV_ILN_2014 GBV_ILN_2015 GBV_ILN_2020 GBV_ILN_2021 GBV_ILN_2025 GBV_ILN_2027 GBV_ILN_2034 GBV_ILN_2038 GBV_ILN_2044 GBV_ILN_2048 GBV_ILN_2049 GBV_ILN_2050 GBV_ILN_2056 GBV_ILN_2059 GBV_ILN_2061 GBV_ILN_2064 GBV_ILN_2065 GBV_ILN_2068 GBV_ILN_2088 GBV_ILN_2111 GBV_ILN_2112 GBV_ILN_2113 GBV_ILN_2118 GBV_ILN_2122 GBV_ILN_2129 GBV_ILN_2143 GBV_ILN_2147 GBV_ILN_2148 GBV_ILN_2152 GBV_ILN_2153 GBV_ILN_2190 GBV_ILN_2336 GBV_ILN_2411 GBV_ILN_2470 GBV_ILN_2507 GBV_ILN_2522 GBV_ILN_4035 GBV_ILN_4037 GBV_ILN_4046 GBV_ILN_4112 GBV_ILN_4125 GBV_ILN_4126 GBV_ILN_4242 GBV_ILN_4251 GBV_ILN_4305 GBV_ILN_4313 GBV_ILN_4322 GBV_ILN_4323 GBV_ILN_4324 GBV_ILN_4326 GBV_ILN_4333 GBV_ILN_4334 GBV_ILN_4335 GBV_ILN_4338 GBV_ILN_4393 35.18 Kolloidchemie Grenzflächenchemie 33.68 Oberflächen Dünne Schichten Grenzflächen Physik 52.78 Oberflächentechnik Wärmebehandlung 58.20 Chemische Technologien: Allgemeines AR 612 |
allfieldsGer |
10.1016/j.colsurfa.2020.125988 doi (DE-627)ELV005455162 (ELSEVIER)S0927-7757(20)31581-8 DE-627 ger DE-627 rda eng 540 DE-600 35.18 bkl 33.68 bkl 52.78 bkl 58.20 bkl Godard, Jérémy verfasserin aut Synthesis and supramolecular arrangement of new stearoyl acid-based phenalenone derivatives 2020 nicht spezifiziert zzz rdacontent Computermedien c rdamedia Online-Ressource cr rdacarrier Lipid-based photoantimicrobial supramolecular assemblies are promising structures for the development of new photodynamic treatments of wound bacterial infections. Phenalenone (1H-phenalene-1-one, PN) has been used to obtain four stearoyl acid-based phenalenone derivatives (PNC18), with different types of linkage and different number of acyl chains. After studying the interfacial properties of these compounds, nano-objects were formed with either pure PNC18 or mixtures of PNC18 with 1-stearoyl-2-oleoyl-sn-glycero-3-phosphocholine. Morphologies of these nano-objects were analyzed by CryoTEM imaging. The distearoyl glycerol PN derivative appears promising for building photosensitive micelles or vesicles. Phenalenone-stearoyl acid conjugate Micelles Vesicles Supramolecular chemistry Self-assembly CryoTem imaging Chapron, David verfasserin aut Bregier, Frédérique verfasserin aut Rosilio, Véronique verfasserin aut Sol, Vincent verfasserin aut Enthalten in Colloids and surfaces / A Amsterdam [u.a.] : Elsevier Science, 1993 612 Online-Ressource (DE-627)306659956 (DE-600)1500517-3 (DE-576)098614843 1873-4359 nnns volume:612 GBV_USEFLAG_U SYSFLAG_U GBV_ELV SSG-OLC-PHA GBV_ILN_20 GBV_ILN_22 GBV_ILN_23 GBV_ILN_24 GBV_ILN_31 GBV_ILN_32 GBV_ILN_40 GBV_ILN_60 GBV_ILN_62 GBV_ILN_63 GBV_ILN_65 GBV_ILN_69 GBV_ILN_70 GBV_ILN_73 GBV_ILN_74 GBV_ILN_90 GBV_ILN_95 GBV_ILN_100 GBV_ILN_101 GBV_ILN_105 GBV_ILN_110 GBV_ILN_150 GBV_ILN_151 GBV_ILN_224 GBV_ILN_370 GBV_ILN_602 GBV_ILN_702 GBV_ILN_2003 GBV_ILN_2004 GBV_ILN_2005 GBV_ILN_2006 GBV_ILN_2008 GBV_ILN_2010 GBV_ILN_2011 GBV_ILN_2014 GBV_ILN_2015 GBV_ILN_2020 GBV_ILN_2021 GBV_ILN_2025 GBV_ILN_2027 GBV_ILN_2034 GBV_ILN_2038 GBV_ILN_2044 GBV_ILN_2048 GBV_ILN_2049 GBV_ILN_2050 GBV_ILN_2056 GBV_ILN_2059 GBV_ILN_2061 GBV_ILN_2064 GBV_ILN_2065 GBV_ILN_2068 GBV_ILN_2088 GBV_ILN_2111 GBV_ILN_2112 GBV_ILN_2113 GBV_ILN_2118 GBV_ILN_2122 GBV_ILN_2129 GBV_ILN_2143 GBV_ILN_2147 GBV_ILN_2148 GBV_ILN_2152 GBV_ILN_2153 GBV_ILN_2190 GBV_ILN_2336 GBV_ILN_2411 GBV_ILN_2470 GBV_ILN_2507 GBV_ILN_2522 GBV_ILN_4035 GBV_ILN_4037 GBV_ILN_4046 GBV_ILN_4112 GBV_ILN_4125 GBV_ILN_4126 GBV_ILN_4242 GBV_ILN_4251 GBV_ILN_4305 GBV_ILN_4313 GBV_ILN_4322 GBV_ILN_4323 GBV_ILN_4324 GBV_ILN_4326 GBV_ILN_4333 GBV_ILN_4334 GBV_ILN_4335 GBV_ILN_4338 GBV_ILN_4393 35.18 Kolloidchemie Grenzflächenchemie 33.68 Oberflächen Dünne Schichten Grenzflächen Physik 52.78 Oberflächentechnik Wärmebehandlung 58.20 Chemische Technologien: Allgemeines AR 612 |
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10.1016/j.colsurfa.2020.125988 doi (DE-627)ELV005455162 (ELSEVIER)S0927-7757(20)31581-8 DE-627 ger DE-627 rda eng 540 DE-600 35.18 bkl 33.68 bkl 52.78 bkl 58.20 bkl Godard, Jérémy verfasserin aut Synthesis and supramolecular arrangement of new stearoyl acid-based phenalenone derivatives 2020 nicht spezifiziert zzz rdacontent Computermedien c rdamedia Online-Ressource cr rdacarrier Lipid-based photoantimicrobial supramolecular assemblies are promising structures for the development of new photodynamic treatments of wound bacterial infections. Phenalenone (1H-phenalene-1-one, PN) has been used to obtain four stearoyl acid-based phenalenone derivatives (PNC18), with different types of linkage and different number of acyl chains. After studying the interfacial properties of these compounds, nano-objects were formed with either pure PNC18 or mixtures of PNC18 with 1-stearoyl-2-oleoyl-sn-glycero-3-phosphocholine. Morphologies of these nano-objects were analyzed by CryoTEM imaging. The distearoyl glycerol PN derivative appears promising for building photosensitive micelles or vesicles. Phenalenone-stearoyl acid conjugate Micelles Vesicles Supramolecular chemistry Self-assembly CryoTem imaging Chapron, David verfasserin aut Bregier, Frédérique verfasserin aut Rosilio, Véronique verfasserin aut Sol, Vincent verfasserin aut Enthalten in Colloids and surfaces / A Amsterdam [u.a.] : Elsevier Science, 1993 612 Online-Ressource (DE-627)306659956 (DE-600)1500517-3 (DE-576)098614843 1873-4359 nnns volume:612 GBV_USEFLAG_U SYSFLAG_U GBV_ELV SSG-OLC-PHA GBV_ILN_20 GBV_ILN_22 GBV_ILN_23 GBV_ILN_24 GBV_ILN_31 GBV_ILN_32 GBV_ILN_40 GBV_ILN_60 GBV_ILN_62 GBV_ILN_63 GBV_ILN_65 GBV_ILN_69 GBV_ILN_70 GBV_ILN_73 GBV_ILN_74 GBV_ILN_90 GBV_ILN_95 GBV_ILN_100 GBV_ILN_101 GBV_ILN_105 GBV_ILN_110 GBV_ILN_150 GBV_ILN_151 GBV_ILN_224 GBV_ILN_370 GBV_ILN_602 GBV_ILN_702 GBV_ILN_2003 GBV_ILN_2004 GBV_ILN_2005 GBV_ILN_2006 GBV_ILN_2008 GBV_ILN_2010 GBV_ILN_2011 GBV_ILN_2014 GBV_ILN_2015 GBV_ILN_2020 GBV_ILN_2021 GBV_ILN_2025 GBV_ILN_2027 GBV_ILN_2034 GBV_ILN_2038 GBV_ILN_2044 GBV_ILN_2048 GBV_ILN_2049 GBV_ILN_2050 GBV_ILN_2056 GBV_ILN_2059 GBV_ILN_2061 GBV_ILN_2064 GBV_ILN_2065 GBV_ILN_2068 GBV_ILN_2088 GBV_ILN_2111 GBV_ILN_2112 GBV_ILN_2113 GBV_ILN_2118 GBV_ILN_2122 GBV_ILN_2129 GBV_ILN_2143 GBV_ILN_2147 GBV_ILN_2148 GBV_ILN_2152 GBV_ILN_2153 GBV_ILN_2190 GBV_ILN_2336 GBV_ILN_2411 GBV_ILN_2470 GBV_ILN_2507 GBV_ILN_2522 GBV_ILN_4035 GBV_ILN_4037 GBV_ILN_4046 GBV_ILN_4112 GBV_ILN_4125 GBV_ILN_4126 GBV_ILN_4242 GBV_ILN_4251 GBV_ILN_4305 GBV_ILN_4313 GBV_ILN_4322 GBV_ILN_4323 GBV_ILN_4324 GBV_ILN_4326 GBV_ILN_4333 GBV_ILN_4334 GBV_ILN_4335 GBV_ILN_4338 GBV_ILN_4393 35.18 Kolloidchemie Grenzflächenchemie 33.68 Oberflächen Dünne Schichten Grenzflächen Physik 52.78 Oberflächentechnik Wärmebehandlung 58.20 Chemische Technologien: Allgemeines AR 612 |
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Kolloidchemie Grenzflächenchemie Oberflächen Dünne Schichten Grenzflächen Oberflächentechnik Wärmebehandlung Chemische Technologien: Allgemeines |
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Phenalenone-stearoyl acid conjugate Micelles Vesicles Supramolecular chemistry Self-assembly CryoTem imaging |
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Godard, Jérémy @@aut@@ Chapron, David @@aut@@ Bregier, Frédérique @@aut@@ Rosilio, Véronique @@aut@@ Sol, Vincent @@aut@@ |
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2020-01-01T00:00:00Z |
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author |
Godard, Jérémy |
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540 DE-600 35.18 bkl 33.68 bkl 52.78 bkl 58.20 bkl Synthesis and supramolecular arrangement of new stearoyl acid-based phenalenone derivatives Phenalenone-stearoyl acid conjugate Micelles Vesicles Supramolecular chemistry Self-assembly CryoTem imaging |
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Synthesis and supramolecular arrangement of new stearoyl acid-based phenalenone derivatives |
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Godard, Jérémy Chapron, David Bregier, Frédérique Rosilio, Véronique Sol, Vincent |
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synthesis and supramolecular arrangement of new stearoyl acid-based phenalenone derivatives |
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Synthesis and supramolecular arrangement of new stearoyl acid-based phenalenone derivatives |
abstract |
Lipid-based photoantimicrobial supramolecular assemblies are promising structures for the development of new photodynamic treatments of wound bacterial infections. Phenalenone (1H-phenalene-1-one, PN) has been used to obtain four stearoyl acid-based phenalenone derivatives (PNC18), with different types of linkage and different number of acyl chains. After studying the interfacial properties of these compounds, nano-objects were formed with either pure PNC18 or mixtures of PNC18 with 1-stearoyl-2-oleoyl-sn-glycero-3-phosphocholine. Morphologies of these nano-objects were analyzed by CryoTEM imaging. The distearoyl glycerol PN derivative appears promising for building photosensitive micelles or vesicles. |
abstractGer |
Lipid-based photoantimicrobial supramolecular assemblies are promising structures for the development of new photodynamic treatments of wound bacterial infections. Phenalenone (1H-phenalene-1-one, PN) has been used to obtain four stearoyl acid-based phenalenone derivatives (PNC18), with different types of linkage and different number of acyl chains. After studying the interfacial properties of these compounds, nano-objects were formed with either pure PNC18 or mixtures of PNC18 with 1-stearoyl-2-oleoyl-sn-glycero-3-phosphocholine. Morphologies of these nano-objects were analyzed by CryoTEM imaging. The distearoyl glycerol PN derivative appears promising for building photosensitive micelles or vesicles. |
abstract_unstemmed |
Lipid-based photoantimicrobial supramolecular assemblies are promising structures for the development of new photodynamic treatments of wound bacterial infections. Phenalenone (1H-phenalene-1-one, PN) has been used to obtain four stearoyl acid-based phenalenone derivatives (PNC18), with different types of linkage and different number of acyl chains. After studying the interfacial properties of these compounds, nano-objects were formed with either pure PNC18 or mixtures of PNC18 with 1-stearoyl-2-oleoyl-sn-glycero-3-phosphocholine. Morphologies of these nano-objects were analyzed by CryoTEM imaging. The distearoyl glycerol PN derivative appears promising for building photosensitive micelles or vesicles. |
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