The impact of invasive respiratory support on the development of postoperative atrial fibrillation following cardiac surgery

Study objective: Postoperative atrial fibrillation (POAF) is a frequent complication after cardiac valve- or coronary artery bypass (CABG) surgery and is associated with increased mortality. While it is known that prolonged postoperative invasive ventilation triggers POAF, the impact of ventilatory...
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Autor*in:	Schnaubelt, Sebastian [verfasserIn] Stajic, Alexander [verfasserIn] Koller, Lorenz [verfasserIn] Hofer, Felix [verfasserIn] Kazem, Niema [verfasserIn] Hammer, Andreas [verfasserIn] Andreas, Martin [verfasserIn] Laufer, Günther [verfasserIn] Steinlechner, Barbara [verfasserIn] Richter, Bernhard [verfasserIn] Niessner, Alexander [verfasserIn] Sulzgruber, Patrick [verfasserIn]

Format:	E-Artikel
Sprache:	Englisch

Erschienen:	2021

Schlagwörter:	Atrial fibrillation Cardiac surgery Ventilatory effort Ventilatory settings Invasive ventilation

Übergeordnetes Werk:	Enthalten in: Journal of clinical anesthesia - Amsterdam [u.a.] : Elsevier Science, 1988, 72
Übergeordnetes Werk:	volume:72

DOI / URN:	10.1016/j.jclinane.2021.110309

Katalog-ID:	ELV006065627

Internformat


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245	1	0	\|a The impact of invasive respiratory support on the development of postoperative atrial fibrillation following cardiac surgery
264		1	\|c 2021
336			\|a nicht spezifiziert \|b zzz \|2 rdacontent
337			\|a Computermedien \|b c \|2 rdamedia
338			\|a Online-Ressource \|b cr \|2 rdacarrier
520			\|a Study objective: Postoperative atrial fibrillation (POAF) is a frequent complication after cardiac valve- or coronary artery bypass (CABG) surgery and is associated with increased mortality. While it is known that prolonged postoperative invasive ventilation triggers POAF, the impact of ventilatory settings on POAF development has not been studied yet.Design: Prospective observational study.Setting: Postoperative Intensive Care Unit.Patients: Patients having undergone elective CABG and/or cardiac valve surgery.Measurements: Screening for the development of POAF. Patients' clinical data and postoperative ventilatory settings (driving pressure, controlled pressure above positive endexpiratory pressure (PEEP), respiration rate, and FiO2) were investigated to elucidate their impact on POAF.Main results: Out of 441 enrolled individuals, a total of 192 participants developed POAF (43.5%). We observed that POAF patients received a higher peak driving pressure, and a higher peak respiration rate than non-POAF individuals. Within the multivariate regression model, plateau pressure (adjusted OR 1.199 [1.038–1.661], p = 0.019), driving pressure (adjusted OR 1.244 [1.103–1.713], p = 0.021), and peak respiration rate (adjusted OR 1.206 [1.005–1.601], p = 0.040) proved to be independently associated with the development of POAF. CART analysis revealed a cut-off of ≥17.5 cmH2O of plateau pressure, ≥11.5 cmH2O of driving pressure and ≥ 17 respirations per minute as high-risk for POAF development.Conclusions: The ventilatory settings of plateau pressure, driving pressure, and respiration rate after cardiac surgery influence POAF occurrence probability. Optimized postoperative care such as lung-protective ventilation and increased awareness towards postoperative ventilatory efforts should be considered to prevent POAF development and poor patient outcome.
650		4	\|a Atrial fibrillation
650		4	\|a Cardiac surgery
650		4	\|a Ventilatory effort
650		4	\|a Ventilatory settings
650		4	\|a Invasive ventilation
700	1		\|a Stajic, Alexander \|e verfasserin \|4 aut
700	1		\|a Koller, Lorenz \|e verfasserin \|4 aut
700	1		\|a Hofer, Felix \|e verfasserin \|4 aut
700	1		\|a Kazem, Niema \|e verfasserin \|4 aut
700	1		\|a Hammer, Andreas \|e verfasserin \|4 aut
700	1		\|a Andreas, Martin \|e verfasserin \|4 aut
700	1		\|a Laufer, Günther \|e verfasserin \|4 aut
700	1		\|a Steinlechner, Barbara \|e verfasserin \|4 aut
700	1		\|a Richter, Bernhard \|e verfasserin \|4 aut
700	1		\|a Niessner, Alexander \|e verfasserin \|4 aut
700	1		\|a Sulzgruber, Patrick \|e verfasserin \|4 aut
773	0	8	\|i Enthalten in \|t Journal of clinical anesthesia \|d Amsterdam [u.a.] : Elsevier Science, 1988 \|g 72 \|h Online-Ressource \|w (DE-627)306659697 \|w (DE-600)1500489-2 \|w (DE-576)081986335 \|x 1873-4529 \|7 nnns
773	1	8	\|g volume:72
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912			\|a GBV_ILN_31
912			\|a GBV_ILN_32
912			\|a GBV_ILN_40
912			\|a GBV_ILN_60
912			\|a GBV_ILN_62
912			\|a GBV_ILN_63
912			\|a GBV_ILN_65
912			\|a GBV_ILN_69
912			\|a GBV_ILN_70
912			\|a GBV_ILN_73
912			\|a GBV_ILN_74
912			\|a GBV_ILN_90
912			\|a GBV_ILN_95
912			\|a GBV_ILN_100
912			\|a GBV_ILN_101
912			\|a GBV_ILN_105
912			\|a GBV_ILN_110
912			\|a GBV_ILN_151
912			\|a GBV_ILN_224
912			\|a GBV_ILN_370
912			\|a GBV_ILN_602
912			\|a GBV_ILN_702
912			\|a GBV_ILN_2003
912			\|a GBV_ILN_2004
912			\|a GBV_ILN_2005
912			\|a GBV_ILN_2011
912			\|a GBV_ILN_2014
912			\|a GBV_ILN_2015
912			\|a GBV_ILN_2020
912			\|a GBV_ILN_2021
912			\|a GBV_ILN_2025
912			\|a GBV_ILN_2027
912			\|a GBV_ILN_2034
912			\|a GBV_ILN_2038
912			\|a GBV_ILN_2044
912			\|a GBV_ILN_2048
912			\|a GBV_ILN_2049
912			\|a GBV_ILN_2050
912			\|a GBV_ILN_2056
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912			\|a GBV_ILN_2061
912			\|a GBV_ILN_2064
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912			\|a GBV_ILN_2111
912			\|a GBV_ILN_2112
912			\|a GBV_ILN_2113
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912			\|a GBV_ILN_2122
912			\|a GBV_ILN_2129
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912			\|a GBV_ILN_2152
912			\|a GBV_ILN_2153
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912			\|a GBV_ILN_2336
912			\|a GBV_ILN_2507
912			\|a GBV_ILN_2522
912			\|a GBV_ILN_4035
912			\|a GBV_ILN_4037
912			\|a GBV_ILN_4112
912			\|a GBV_ILN_4125
912			\|a GBV_ILN_4126
912			\|a GBV_ILN_4242
912			\|a GBV_ILN_4251
912			\|a GBV_ILN_4305
912			\|a GBV_ILN_4313
912			\|a GBV_ILN_4323
912			\|a GBV_ILN_4324
912			\|a GBV_ILN_4325
912			\|a GBV_ILN_4326
912			\|a GBV_ILN_4333
912			\|a GBV_ILN_4334
912			\|a GBV_ILN_4335
912			\|a GBV_ILN_4338
912			\|a GBV_ILN_4393
936	b	k	\|a 44.66 \|j Anästhesiologie
951			\|a AR
952			\|d 72

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publishDate	2021
allfields	10.1016/j.jclinane.2021.110309 doi (DE-627)ELV006065627 (ELSEVIER)S0952-8180(21)00148-3 DE-627 ger DE-627 rda eng 610 DE-600 44.66 bkl Schnaubelt, Sebastian verfasserin aut The impact of invasive respiratory support on the development of postoperative atrial fibrillation following cardiac surgery 2021 nicht spezifiziert zzz rdacontent Computermedien c rdamedia Online-Ressource cr rdacarrier Study objective: Postoperative atrial fibrillation (POAF) is a frequent complication after cardiac valve- or coronary artery bypass (CABG) surgery and is associated with increased mortality. While it is known that prolonged postoperative invasive ventilation triggers POAF, the impact of ventilatory settings on POAF development has not been studied yet.Design: Prospective observational study.Setting: Postoperative Intensive Care Unit.Patients: Patients having undergone elective CABG and/or cardiac valve surgery.Measurements: Screening for the development of POAF. Patients' clinical data and postoperative ventilatory settings (driving pressure, controlled pressure above positive endexpiratory pressure (PEEP), respiration rate, and FiO2) were investigated to elucidate their impact on POAF.Main results: Out of 441 enrolled individuals, a total of 192 participants developed POAF (43.5%). We observed that POAF patients received a higher peak driving pressure, and a higher peak respiration rate than non-POAF individuals. Within the multivariate regression model, plateau pressure (adjusted OR 1.199 [1.038–1.661], p = 0.019), driving pressure (adjusted OR 1.244 [1.103–1.713], p = 0.021), and peak respiration rate (adjusted OR 1.206 [1.005–1.601], p = 0.040) proved to be independently associated with the development of POAF. CART analysis revealed a cut-off of ≥17.5 cmH2O of plateau pressure, ≥11.5 cmH2O of driving pressure and ≥ 17 respirations per minute as high-risk for POAF development.Conclusions: The ventilatory settings of plateau pressure, driving pressure, and respiration rate after cardiac surgery influence POAF occurrence probability. Optimized postoperative care such as lung-protective ventilation and increased awareness towards postoperative ventilatory efforts should be considered to prevent POAF development and poor patient outcome. Atrial fibrillation Cardiac surgery Ventilatory effort Ventilatory settings Invasive ventilation Stajic, Alexander verfasserin aut Koller, Lorenz verfasserin aut Hofer, Felix verfasserin aut Kazem, Niema verfasserin aut Hammer, Andreas verfasserin aut Andreas, Martin verfasserin aut Laufer, Günther verfasserin aut Steinlechner, Barbara verfasserin aut Richter, Bernhard verfasserin aut Niessner, Alexander verfasserin aut Sulzgruber, Patrick verfasserin aut Enthalten in Journal of clinical anesthesia Amsterdam [u.a.] : Elsevier Science, 1988 72 Online-Ressource (DE-627)306659697 (DE-600)1500489-2 (DE-576)081986335 1873-4529 nnns volume:72 GBV_USEFLAG_U SYSFLAG_U GBV_ELV SSG-OLC-PHA GBV_ILN_20 GBV_ILN_22 GBV_ILN_23 GBV_ILN_24 GBV_ILN_31 GBV_ILN_32 GBV_ILN_40 GBV_ILN_60 GBV_ILN_62 GBV_ILN_63 GBV_ILN_65 GBV_ILN_69 GBV_ILN_70 GBV_ILN_73 GBV_ILN_74 GBV_ILN_90 GBV_ILN_95 GBV_ILN_100 GBV_ILN_101 GBV_ILN_105 GBV_ILN_110 GBV_ILN_151 GBV_ILN_224 GBV_ILN_370 GBV_ILN_602 GBV_ILN_702 GBV_ILN_2003 GBV_ILN_2004 GBV_ILN_2005 GBV_ILN_2011 GBV_ILN_2014 GBV_ILN_2015 GBV_ILN_2020 GBV_ILN_2021 GBV_ILN_2025 GBV_ILN_2027 GBV_ILN_2034 GBV_ILN_2038 GBV_ILN_2044 GBV_ILN_2048 GBV_ILN_2049 GBV_ILN_2050 GBV_ILN_2056 GBV_ILN_2059 GBV_ILN_2061 GBV_ILN_2064 GBV_ILN_2065 GBV_ILN_2068 GBV_ILN_2111 GBV_ILN_2112 GBV_ILN_2113 GBV_ILN_2118 GBV_ILN_2122 GBV_ILN_2129 GBV_ILN_2143 GBV_ILN_2147 GBV_ILN_2148 GBV_ILN_2152 GBV_ILN_2153 GBV_ILN_2190 GBV_ILN_2336 GBV_ILN_2507 GBV_ILN_2522 GBV_ILN_4035 GBV_ILN_4037 GBV_ILN_4112 GBV_ILN_4125 GBV_ILN_4126 GBV_ILN_4242 GBV_ILN_4251 GBV_ILN_4305 GBV_ILN_4313 GBV_ILN_4323 GBV_ILN_4324 GBV_ILN_4325 GBV_ILN_4326 GBV_ILN_4333 GBV_ILN_4334 GBV_ILN_4335 GBV_ILN_4338 GBV_ILN_4393 44.66 Anästhesiologie AR 72
spelling	10.1016/j.jclinane.2021.110309 doi (DE-627)ELV006065627 (ELSEVIER)S0952-8180(21)00148-3 DE-627 ger DE-627 rda eng 610 DE-600 44.66 bkl Schnaubelt, Sebastian verfasserin aut The impact of invasive respiratory support on the development of postoperative atrial fibrillation following cardiac surgery 2021 nicht spezifiziert zzz rdacontent Computermedien c rdamedia Online-Ressource cr rdacarrier Study objective: Postoperative atrial fibrillation (POAF) is a frequent complication after cardiac valve- or coronary artery bypass (CABG) surgery and is associated with increased mortality. While it is known that prolonged postoperative invasive ventilation triggers POAF, the impact of ventilatory settings on POAF development has not been studied yet.Design: Prospective observational study.Setting: Postoperative Intensive Care Unit.Patients: Patients having undergone elective CABG and/or cardiac valve surgery.Measurements: Screening for the development of POAF. Patients' clinical data and postoperative ventilatory settings (driving pressure, controlled pressure above positive endexpiratory pressure (PEEP), respiration rate, and FiO2) were investigated to elucidate their impact on POAF.Main results: Out of 441 enrolled individuals, a total of 192 participants developed POAF (43.5%). We observed that POAF patients received a higher peak driving pressure, and a higher peak respiration rate than non-POAF individuals. Within the multivariate regression model, plateau pressure (adjusted OR 1.199 [1.038–1.661], p = 0.019), driving pressure (adjusted OR 1.244 [1.103–1.713], p = 0.021), and peak respiration rate (adjusted OR 1.206 [1.005–1.601], p = 0.040) proved to be independently associated with the development of POAF. CART analysis revealed a cut-off of ≥17.5 cmH2O of plateau pressure, ≥11.5 cmH2O of driving pressure and ≥ 17 respirations per minute as high-risk for POAF development.Conclusions: The ventilatory settings of plateau pressure, driving pressure, and respiration rate after cardiac surgery influence POAF occurrence probability. Optimized postoperative care such as lung-protective ventilation and increased awareness towards postoperative ventilatory efforts should be considered to prevent POAF development and poor patient outcome. Atrial fibrillation Cardiac surgery Ventilatory effort Ventilatory settings Invasive ventilation Stajic, Alexander verfasserin aut Koller, Lorenz verfasserin aut Hofer, Felix verfasserin aut Kazem, Niema verfasserin aut Hammer, Andreas verfasserin aut Andreas, Martin verfasserin aut Laufer, Günther verfasserin aut Steinlechner, Barbara verfasserin aut Richter, Bernhard verfasserin aut Niessner, Alexander verfasserin aut Sulzgruber, Patrick verfasserin aut Enthalten in Journal of clinical anesthesia Amsterdam [u.a.] : Elsevier Science, 1988 72 Online-Ressource (DE-627)306659697 (DE-600)1500489-2 (DE-576)081986335 1873-4529 nnns volume:72 GBV_USEFLAG_U SYSFLAG_U GBV_ELV SSG-OLC-PHA GBV_ILN_20 GBV_ILN_22 GBV_ILN_23 GBV_ILN_24 GBV_ILN_31 GBV_ILN_32 GBV_ILN_40 GBV_ILN_60 GBV_ILN_62 GBV_ILN_63 GBV_ILN_65 GBV_ILN_69 GBV_ILN_70 GBV_ILN_73 GBV_ILN_74 GBV_ILN_90 GBV_ILN_95 GBV_ILN_100 GBV_ILN_101 GBV_ILN_105 GBV_ILN_110 GBV_ILN_151 GBV_ILN_224 GBV_ILN_370 GBV_ILN_602 GBV_ILN_702 GBV_ILN_2003 GBV_ILN_2004 GBV_ILN_2005 GBV_ILN_2011 GBV_ILN_2014 GBV_ILN_2015 GBV_ILN_2020 GBV_ILN_2021 GBV_ILN_2025 GBV_ILN_2027 GBV_ILN_2034 GBV_ILN_2038 GBV_ILN_2044 GBV_ILN_2048 GBV_ILN_2049 GBV_ILN_2050 GBV_ILN_2056 GBV_ILN_2059 GBV_ILN_2061 GBV_ILN_2064 GBV_ILN_2065 GBV_ILN_2068 GBV_ILN_2111 GBV_ILN_2112 GBV_ILN_2113 GBV_ILN_2118 GBV_ILN_2122 GBV_ILN_2129 GBV_ILN_2143 GBV_ILN_2147 GBV_ILN_2148 GBV_ILN_2152 GBV_ILN_2153 GBV_ILN_2190 GBV_ILN_2336 GBV_ILN_2507 GBV_ILN_2522 GBV_ILN_4035 GBV_ILN_4037 GBV_ILN_4112 GBV_ILN_4125 GBV_ILN_4126 GBV_ILN_4242 GBV_ILN_4251 GBV_ILN_4305 GBV_ILN_4313 GBV_ILN_4323 GBV_ILN_4324 GBV_ILN_4325 GBV_ILN_4326 GBV_ILN_4333 GBV_ILN_4334 GBV_ILN_4335 GBV_ILN_4338 GBV_ILN_4393 44.66 Anästhesiologie AR 72
allfields_unstemmed	10.1016/j.jclinane.2021.110309 doi (DE-627)ELV006065627 (ELSEVIER)S0952-8180(21)00148-3 DE-627 ger DE-627 rda eng 610 DE-600 44.66 bkl Schnaubelt, Sebastian verfasserin aut The impact of invasive respiratory support on the development of postoperative atrial fibrillation following cardiac surgery 2021 nicht spezifiziert zzz rdacontent Computermedien c rdamedia Online-Ressource cr rdacarrier Study objective: Postoperative atrial fibrillation (POAF) is a frequent complication after cardiac valve- or coronary artery bypass (CABG) surgery and is associated with increased mortality. While it is known that prolonged postoperative invasive ventilation triggers POAF, the impact of ventilatory settings on POAF development has not been studied yet.Design: Prospective observational study.Setting: Postoperative Intensive Care Unit.Patients: Patients having undergone elective CABG and/or cardiac valve surgery.Measurements: Screening for the development of POAF. Patients' clinical data and postoperative ventilatory settings (driving pressure, controlled pressure above positive endexpiratory pressure (PEEP), respiration rate, and FiO2) were investigated to elucidate their impact on POAF.Main results: Out of 441 enrolled individuals, a total of 192 participants developed POAF (43.5%). We observed that POAF patients received a higher peak driving pressure, and a higher peak respiration rate than non-POAF individuals. Within the multivariate regression model, plateau pressure (adjusted OR 1.199 [1.038–1.661], p = 0.019), driving pressure (adjusted OR 1.244 [1.103–1.713], p = 0.021), and peak respiration rate (adjusted OR 1.206 [1.005–1.601], p = 0.040) proved to be independently associated with the development of POAF. CART analysis revealed a cut-off of ≥17.5 cmH2O of plateau pressure, ≥11.5 cmH2O of driving pressure and ≥ 17 respirations per minute as high-risk for POAF development.Conclusions: The ventilatory settings of plateau pressure, driving pressure, and respiration rate after cardiac surgery influence POAF occurrence probability. Optimized postoperative care such as lung-protective ventilation and increased awareness towards postoperative ventilatory efforts should be considered to prevent POAF development and poor patient outcome. Atrial fibrillation Cardiac surgery Ventilatory effort Ventilatory settings Invasive ventilation Stajic, Alexander verfasserin aut Koller, Lorenz verfasserin aut Hofer, Felix verfasserin aut Kazem, Niema verfasserin aut Hammer, Andreas verfasserin aut Andreas, Martin verfasserin aut Laufer, Günther verfasserin aut Steinlechner, Barbara verfasserin aut Richter, Bernhard verfasserin aut Niessner, Alexander verfasserin aut Sulzgruber, Patrick verfasserin aut Enthalten in Journal of clinical anesthesia Amsterdam [u.a.] : Elsevier Science, 1988 72 Online-Ressource (DE-627)306659697 (DE-600)1500489-2 (DE-576)081986335 1873-4529 nnns volume:72 GBV_USEFLAG_U SYSFLAG_U GBV_ELV SSG-OLC-PHA GBV_ILN_20 GBV_ILN_22 GBV_ILN_23 GBV_ILN_24 GBV_ILN_31 GBV_ILN_32 GBV_ILN_40 GBV_ILN_60 GBV_ILN_62 GBV_ILN_63 GBV_ILN_65 GBV_ILN_69 GBV_ILN_70 GBV_ILN_73 GBV_ILN_74 GBV_ILN_90 GBV_ILN_95 GBV_ILN_100 GBV_ILN_101 GBV_ILN_105 GBV_ILN_110 GBV_ILN_151 GBV_ILN_224 GBV_ILN_370 GBV_ILN_602 GBV_ILN_702 GBV_ILN_2003 GBV_ILN_2004 GBV_ILN_2005 GBV_ILN_2011 GBV_ILN_2014 GBV_ILN_2015 GBV_ILN_2020 GBV_ILN_2021 GBV_ILN_2025 GBV_ILN_2027 GBV_ILN_2034 GBV_ILN_2038 GBV_ILN_2044 GBV_ILN_2048 GBV_ILN_2049 GBV_ILN_2050 GBV_ILN_2056 GBV_ILN_2059 GBV_ILN_2061 GBV_ILN_2064 GBV_ILN_2065 GBV_ILN_2068 GBV_ILN_2111 GBV_ILN_2112 GBV_ILN_2113 GBV_ILN_2118 GBV_ILN_2122 GBV_ILN_2129 GBV_ILN_2143 GBV_ILN_2147 GBV_ILN_2148 GBV_ILN_2152 GBV_ILN_2153 GBV_ILN_2190 GBV_ILN_2336 GBV_ILN_2507 GBV_ILN_2522 GBV_ILN_4035 GBV_ILN_4037 GBV_ILN_4112 GBV_ILN_4125 GBV_ILN_4126 GBV_ILN_4242 GBV_ILN_4251 GBV_ILN_4305 GBV_ILN_4313 GBV_ILN_4323 GBV_ILN_4324 GBV_ILN_4325 GBV_ILN_4326 GBV_ILN_4333 GBV_ILN_4334 GBV_ILN_4335 GBV_ILN_4338 GBV_ILN_4393 44.66 Anästhesiologie AR 72
allfieldsGer	10.1016/j.jclinane.2021.110309 doi (DE-627)ELV006065627 (ELSEVIER)S0952-8180(21)00148-3 DE-627 ger DE-627 rda eng 610 DE-600 44.66 bkl Schnaubelt, Sebastian verfasserin aut The impact of invasive respiratory support on the development of postoperative atrial fibrillation following cardiac surgery 2021 nicht spezifiziert zzz rdacontent Computermedien c rdamedia Online-Ressource cr rdacarrier Study objective: Postoperative atrial fibrillation (POAF) is a frequent complication after cardiac valve- or coronary artery bypass (CABG) surgery and is associated with increased mortality. While it is known that prolonged postoperative invasive ventilation triggers POAF, the impact of ventilatory settings on POAF development has not been studied yet.Design: Prospective observational study.Setting: Postoperative Intensive Care Unit.Patients: Patients having undergone elective CABG and/or cardiac valve surgery.Measurements: Screening for the development of POAF. Patients' clinical data and postoperative ventilatory settings (driving pressure, controlled pressure above positive endexpiratory pressure (PEEP), respiration rate, and FiO2) were investigated to elucidate their impact on POAF.Main results: Out of 441 enrolled individuals, a total of 192 participants developed POAF (43.5%). We observed that POAF patients received a higher peak driving pressure, and a higher peak respiration rate than non-POAF individuals. Within the multivariate regression model, plateau pressure (adjusted OR 1.199 [1.038–1.661], p = 0.019), driving pressure (adjusted OR 1.244 [1.103–1.713], p = 0.021), and peak respiration rate (adjusted OR 1.206 [1.005–1.601], p = 0.040) proved to be independently associated with the development of POAF. CART analysis revealed a cut-off of ≥17.5 cmH2O of plateau pressure, ≥11.5 cmH2O of driving pressure and ≥ 17 respirations per minute as high-risk for POAF development.Conclusions: The ventilatory settings of plateau pressure, driving pressure, and respiration rate after cardiac surgery influence POAF occurrence probability. Optimized postoperative care such as lung-protective ventilation and increased awareness towards postoperative ventilatory efforts should be considered to prevent POAF development and poor patient outcome. Atrial fibrillation Cardiac surgery Ventilatory effort Ventilatory settings Invasive ventilation Stajic, Alexander verfasserin aut Koller, Lorenz verfasserin aut Hofer, Felix verfasserin aut Kazem, Niema verfasserin aut Hammer, Andreas verfasserin aut Andreas, Martin verfasserin aut Laufer, Günther verfasserin aut Steinlechner, Barbara verfasserin aut Richter, Bernhard verfasserin aut Niessner, Alexander verfasserin aut Sulzgruber, Patrick verfasserin aut Enthalten in Journal of clinical anesthesia Amsterdam [u.a.] : Elsevier Science, 1988 72 Online-Ressource (DE-627)306659697 (DE-600)1500489-2 (DE-576)081986335 1873-4529 nnns volume:72 GBV_USEFLAG_U SYSFLAG_U GBV_ELV SSG-OLC-PHA GBV_ILN_20 GBV_ILN_22 GBV_ILN_23 GBV_ILN_24 GBV_ILN_31 GBV_ILN_32 GBV_ILN_40 GBV_ILN_60 GBV_ILN_62 GBV_ILN_63 GBV_ILN_65 GBV_ILN_69 GBV_ILN_70 GBV_ILN_73 GBV_ILN_74 GBV_ILN_90 GBV_ILN_95 GBV_ILN_100 GBV_ILN_101 GBV_ILN_105 GBV_ILN_110 GBV_ILN_151 GBV_ILN_224 GBV_ILN_370 GBV_ILN_602 GBV_ILN_702 GBV_ILN_2003 GBV_ILN_2004 GBV_ILN_2005 GBV_ILN_2011 GBV_ILN_2014 GBV_ILN_2015 GBV_ILN_2020 GBV_ILN_2021 GBV_ILN_2025 GBV_ILN_2027 GBV_ILN_2034 GBV_ILN_2038 GBV_ILN_2044 GBV_ILN_2048 GBV_ILN_2049 GBV_ILN_2050 GBV_ILN_2056 GBV_ILN_2059 GBV_ILN_2061 GBV_ILN_2064 GBV_ILN_2065 GBV_ILN_2068 GBV_ILN_2111 GBV_ILN_2112 GBV_ILN_2113 GBV_ILN_2118 GBV_ILN_2122 GBV_ILN_2129 GBV_ILN_2143 GBV_ILN_2147 GBV_ILN_2148 GBV_ILN_2152 GBV_ILN_2153 GBV_ILN_2190 GBV_ILN_2336 GBV_ILN_2507 GBV_ILN_2522 GBV_ILN_4035 GBV_ILN_4037 GBV_ILN_4112 GBV_ILN_4125 GBV_ILN_4126 GBV_ILN_4242 GBV_ILN_4251 GBV_ILN_4305 GBV_ILN_4313 GBV_ILN_4323 GBV_ILN_4324 GBV_ILN_4325 GBV_ILN_4326 GBV_ILN_4333 GBV_ILN_4334 GBV_ILN_4335 GBV_ILN_4338 GBV_ILN_4393 44.66 Anästhesiologie AR 72
allfieldsSound	10.1016/j.jclinane.2021.110309 doi (DE-627)ELV006065627 (ELSEVIER)S0952-8180(21)00148-3 DE-627 ger DE-627 rda eng 610 DE-600 44.66 bkl Schnaubelt, Sebastian verfasserin aut The impact of invasive respiratory support on the development of postoperative atrial fibrillation following cardiac surgery 2021 nicht spezifiziert zzz rdacontent Computermedien c rdamedia Online-Ressource cr rdacarrier Study objective: Postoperative atrial fibrillation (POAF) is a frequent complication after cardiac valve- or coronary artery bypass (CABG) surgery and is associated with increased mortality. While it is known that prolonged postoperative invasive ventilation triggers POAF, the impact of ventilatory settings on POAF development has not been studied yet.Design: Prospective observational study.Setting: Postoperative Intensive Care Unit.Patients: Patients having undergone elective CABG and/or cardiac valve surgery.Measurements: Screening for the development of POAF. Patients' clinical data and postoperative ventilatory settings (driving pressure, controlled pressure above positive endexpiratory pressure (PEEP), respiration rate, and FiO2) were investigated to elucidate their impact on POAF.Main results: Out of 441 enrolled individuals, a total of 192 participants developed POAF (43.5%). We observed that POAF patients received a higher peak driving pressure, and a higher peak respiration rate than non-POAF individuals. Within the multivariate regression model, plateau pressure (adjusted OR 1.199 [1.038–1.661], p = 0.019), driving pressure (adjusted OR 1.244 [1.103–1.713], p = 0.021), and peak respiration rate (adjusted OR 1.206 [1.005–1.601], p = 0.040) proved to be independently associated with the development of POAF. CART analysis revealed a cut-off of ≥17.5 cmH2O of plateau pressure, ≥11.5 cmH2O of driving pressure and ≥ 17 respirations per minute as high-risk for POAF development.Conclusions: The ventilatory settings of plateau pressure, driving pressure, and respiration rate after cardiac surgery influence POAF occurrence probability. Optimized postoperative care such as lung-protective ventilation and increased awareness towards postoperative ventilatory efforts should be considered to prevent POAF development and poor patient outcome. Atrial fibrillation Cardiac surgery Ventilatory effort Ventilatory settings Invasive ventilation Stajic, Alexander verfasserin aut Koller, Lorenz verfasserin aut Hofer, Felix verfasserin aut Kazem, Niema verfasserin aut Hammer, Andreas verfasserin aut Andreas, Martin verfasserin aut Laufer, Günther verfasserin aut Steinlechner, Barbara verfasserin aut Richter, Bernhard verfasserin aut Niessner, Alexander verfasserin aut Sulzgruber, Patrick verfasserin aut Enthalten in Journal of clinical anesthesia Amsterdam [u.a.] : Elsevier Science, 1988 72 Online-Ressource (DE-627)306659697 (DE-600)1500489-2 (DE-576)081986335 1873-4529 nnns volume:72 GBV_USEFLAG_U SYSFLAG_U GBV_ELV SSG-OLC-PHA GBV_ILN_20 GBV_ILN_22 GBV_ILN_23 GBV_ILN_24 GBV_ILN_31 GBV_ILN_32 GBV_ILN_40 GBV_ILN_60 GBV_ILN_62 GBV_ILN_63 GBV_ILN_65 GBV_ILN_69 GBV_ILN_70 GBV_ILN_73 GBV_ILN_74 GBV_ILN_90 GBV_ILN_95 GBV_ILN_100 GBV_ILN_101 GBV_ILN_105 GBV_ILN_110 GBV_ILN_151 GBV_ILN_224 GBV_ILN_370 GBV_ILN_602 GBV_ILN_702 GBV_ILN_2003 GBV_ILN_2004 GBV_ILN_2005 GBV_ILN_2011 GBV_ILN_2014 GBV_ILN_2015 GBV_ILN_2020 GBV_ILN_2021 GBV_ILN_2025 GBV_ILN_2027 GBV_ILN_2034 GBV_ILN_2038 GBV_ILN_2044 GBV_ILN_2048 GBV_ILN_2049 GBV_ILN_2050 GBV_ILN_2056 GBV_ILN_2059 GBV_ILN_2061 GBV_ILN_2064 GBV_ILN_2065 GBV_ILN_2068 GBV_ILN_2111 GBV_ILN_2112 GBV_ILN_2113 GBV_ILN_2118 GBV_ILN_2122 GBV_ILN_2129 GBV_ILN_2143 GBV_ILN_2147 GBV_ILN_2148 GBV_ILN_2152 GBV_ILN_2153 GBV_ILN_2190 GBV_ILN_2336 GBV_ILN_2507 GBV_ILN_2522 GBV_ILN_4035 GBV_ILN_4037 GBV_ILN_4112 GBV_ILN_4125 GBV_ILN_4126 GBV_ILN_4242 GBV_ILN_4251 GBV_ILN_4305 GBV_ILN_4313 GBV_ILN_4323 GBV_ILN_4324 GBV_ILN_4325 GBV_ILN_4326 GBV_ILN_4333 GBV_ILN_4334 GBV_ILN_4335 GBV_ILN_4338 GBV_ILN_4393 44.66 Anästhesiologie AR 72
language	English
source	Enthalten in Journal of clinical anesthesia 72 volume:72
sourceStr	Enthalten in Journal of clinical anesthesia 72 volume:72
format_phy_str_mv	Article
bklname	Anästhesiologie
institution	findex.gbv.de
topic_facet	Atrial fibrillation Cardiac surgery Ventilatory effort Ventilatory settings Invasive ventilation
dewey-raw	610
isfreeaccess_bool	false
container_title	Journal of clinical anesthesia
authorswithroles_txt_mv	Schnaubelt, Sebastian @@aut@@ Stajic, Alexander @@aut@@ Koller, Lorenz @@aut@@ Hofer, Felix @@aut@@ Kazem, Niema @@aut@@ Hammer, Andreas @@aut@@ Andreas, Martin @@aut@@ Laufer, Günther @@aut@@ Steinlechner, Barbara @@aut@@ Richter, Bernhard @@aut@@ Niessner, Alexander @@aut@@ Sulzgruber, Patrick @@aut@@
publishDateDaySort_date	2021-01-01T00:00:00Z
hierarchy_top_id	306659697
dewey-sort	3610
id	ELV006065627
language_de	englisch
fullrecord	<?xml version="1.0" encoding="UTF-8"?><collection xmlns="http://www.loc.gov/MARC21/slim"><record><leader>01000caa a22002652 4500</leader><controlfield tag="001">ELV006065627</controlfield><controlfield tag="003">DE-627</controlfield><controlfield tag="005">20230524152819.0</controlfield><controlfield tag="007">cr uuu---uuuuu</controlfield><controlfield tag="008">230505s2021 xx \|\|\|\|\|o 00\| \|\|eng c</controlfield><datafield tag="024" ind1="7" ind2=" "><subfield code="a">10.1016/j.jclinane.2021.110309</subfield><subfield code="2">doi</subfield></datafield><datafield tag="035" ind1=" " ind2=" "><subfield code="a">(DE-627)ELV006065627</subfield></datafield><datafield tag="035" ind1=" " ind2=" "><subfield code="a">(ELSEVIER)S0952-8180(21)00148-3</subfield></datafield><datafield tag="040" ind1=" " ind2=" "><subfield code="a">DE-627</subfield><subfield code="b">ger</subfield><subfield code="c">DE-627</subfield><subfield code="e">rda</subfield></datafield><datafield tag="041" ind1=" " ind2=" "><subfield code="a">eng</subfield></datafield><datafield tag="082" ind1="0" ind2="4"><subfield code="a">610</subfield><subfield code="q">DE-600</subfield></datafield><datafield tag="084" ind1=" " ind2=" "><subfield code="a">44.66</subfield><subfield code="2">bkl</subfield></datafield><datafield tag="100" ind1="1" ind2=" "><subfield code="a">Schnaubelt, Sebastian</subfield><subfield code="e">verfasserin</subfield><subfield code="4">aut</subfield></datafield><datafield tag="245" ind1="1" ind2="0"><subfield code="a">The impact of invasive respiratory support on the development of postoperative atrial fibrillation following cardiac surgery</subfield></datafield><datafield tag="264" ind1=" " ind2="1"><subfield code="c">2021</subfield></datafield><datafield tag="336" ind1=" " ind2=" "><subfield code="a">nicht spezifiziert</subfield><subfield code="b">zzz</subfield><subfield code="2">rdacontent</subfield></datafield><datafield tag="337" ind1=" " ind2=" "><subfield code="a">Computermedien</subfield><subfield code="b">c</subfield><subfield code="2">rdamedia</subfield></datafield><datafield tag="338" ind1=" " ind2=" "><subfield code="a">Online-Ressource</subfield><subfield code="b">cr</subfield><subfield code="2">rdacarrier</subfield></datafield><datafield tag="520" ind1=" " ind2=" "><subfield code="a">Study objective: Postoperative atrial fibrillation (POAF) is a frequent complication after cardiac valve- or coronary artery bypass (CABG) surgery and is associated with increased mortality. While it is known that prolonged postoperative invasive ventilation triggers POAF, the impact of ventilatory settings on POAF development has not been studied yet.Design: Prospective observational study.Setting: Postoperative Intensive Care Unit.Patients: Patients having undergone elective CABG and/or cardiac valve surgery.Measurements: Screening for the development of POAF. Patients' clinical data and postoperative ventilatory settings (driving pressure, controlled pressure above positive endexpiratory pressure (PEEP), respiration rate, and FiO2) were investigated to elucidate their impact on POAF.Main results: Out of 441 enrolled individuals, a total of 192 participants developed POAF (43.5%). We observed that POAF patients received a higher peak driving pressure, and a higher peak respiration rate than non-POAF individuals. Within the multivariate regression model, plateau pressure (adjusted OR 1.199 [1.038–1.661], p = 0.019), driving pressure (adjusted OR 1.244 [1.103–1.713], p = 0.021), and peak respiration rate (adjusted OR 1.206 [1.005–1.601], p = 0.040) proved to be independently associated with the development of POAF. CART analysis revealed a cut-off of ≥17.5 cmH2O of plateau pressure, ≥11.5 cmH2O of driving pressure and ≥ 17 respirations per minute as high-risk for POAF development.Conclusions: The ventilatory settings of plateau pressure, driving pressure, and respiration rate after cardiac surgery influence POAF occurrence probability. Optimized postoperative care such as lung-protective ventilation and increased awareness towards postoperative ventilatory efforts should be considered to prevent POAF development and poor patient outcome.</subfield></datafield><datafield tag="650" ind1=" " ind2="4"><subfield code="a">Atrial fibrillation</subfield></datafield><datafield tag="650" ind1=" " ind2="4"><subfield code="a">Cardiac surgery</subfield></datafield><datafield tag="650" ind1=" " ind2="4"><subfield code="a">Ventilatory effort</subfield></datafield><datafield tag="650" ind1=" " ind2="4"><subfield code="a">Ventilatory settings</subfield></datafield><datafield tag="650" ind1=" " ind2="4"><subfield code="a">Invasive ventilation</subfield></datafield><datafield tag="700" ind1="1" ind2=" "><subfield code="a">Stajic, Alexander</subfield><subfield code="e">verfasserin</subfield><subfield code="4">aut</subfield></datafield><datafield tag="700" ind1="1" ind2=" "><subfield code="a">Koller, Lorenz</subfield><subfield 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author	Schnaubelt, Sebastian
spellingShingle	Schnaubelt, Sebastian ddc 610 bkl 44.66 misc Atrial fibrillation misc Cardiac surgery misc Ventilatory effort misc Ventilatory settings misc Invasive ventilation The impact of invasive respiratory support on the development of postoperative atrial fibrillation following cardiac surgery
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topic_title	610 DE-600 44.66 bkl The impact of invasive respiratory support on the development of postoperative atrial fibrillation following cardiac surgery Atrial fibrillation Cardiac surgery Ventilatory effort Ventilatory settings Invasive ventilation
topic	ddc 610 bkl 44.66 misc Atrial fibrillation misc Cardiac surgery misc Ventilatory effort misc Ventilatory settings misc Invasive ventilation
topic_unstemmed	ddc 610 bkl 44.66 misc Atrial fibrillation misc Cardiac surgery misc Ventilatory effort misc Ventilatory settings misc Invasive ventilation
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title	The impact of invasive respiratory support on the development of postoperative atrial fibrillation following cardiac surgery
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title_full	The impact of invasive respiratory support on the development of postoperative atrial fibrillation following cardiac surgery
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author_browse	Schnaubelt, Sebastian Stajic, Alexander Koller, Lorenz Hofer, Felix Kazem, Niema Hammer, Andreas Andreas, Martin Laufer, Günther Steinlechner, Barbara Richter, Bernhard Niessner, Alexander Sulzgruber, Patrick
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title_sort	the impact of invasive respiratory support on the development of postoperative atrial fibrillation following cardiac surgery
title_auth	The impact of invasive respiratory support on the development of postoperative atrial fibrillation following cardiac surgery
abstract	Study objective: Postoperative atrial fibrillation (POAF) is a frequent complication after cardiac valve- or coronary artery bypass (CABG) surgery and is associated with increased mortality. While it is known that prolonged postoperative invasive ventilation triggers POAF, the impact of ventilatory settings on POAF development has not been studied yet.Design: Prospective observational study.Setting: Postoperative Intensive Care Unit.Patients: Patients having undergone elective CABG and/or cardiac valve surgery.Measurements: Screening for the development of POAF. Patients' clinical data and postoperative ventilatory settings (driving pressure, controlled pressure above positive endexpiratory pressure (PEEP), respiration rate, and FiO2) were investigated to elucidate their impact on POAF.Main results: Out of 441 enrolled individuals, a total of 192 participants developed POAF (43.5%). We observed that POAF patients received a higher peak driving pressure, and a higher peak respiration rate than non-POAF individuals. Within the multivariate regression model, plateau pressure (adjusted OR 1.199 [1.038–1.661], p = 0.019), driving pressure (adjusted OR 1.244 [1.103–1.713], p = 0.021), and peak respiration rate (adjusted OR 1.206 [1.005–1.601], p = 0.040) proved to be independently associated with the development of POAF. CART analysis revealed a cut-off of ≥17.5 cmH2O of plateau pressure, ≥11.5 cmH2O of driving pressure and ≥ 17 respirations per minute as high-risk for POAF development.Conclusions: The ventilatory settings of plateau pressure, driving pressure, and respiration rate after cardiac surgery influence POAF occurrence probability. Optimized postoperative care such as lung-protective ventilation and increased awareness towards postoperative ventilatory efforts should be considered to prevent POAF development and poor patient outcome.
abstractGer	Study objective: Postoperative atrial fibrillation (POAF) is a frequent complication after cardiac valve- or coronary artery bypass (CABG) surgery and is associated with increased mortality. While it is known that prolonged postoperative invasive ventilation triggers POAF, the impact of ventilatory settings on POAF development has not been studied yet.Design: Prospective observational study.Setting: Postoperative Intensive Care Unit.Patients: Patients having undergone elective CABG and/or cardiac valve surgery.Measurements: Screening for the development of POAF. Patients' clinical data and postoperative ventilatory settings (driving pressure, controlled pressure above positive endexpiratory pressure (PEEP), respiration rate, and FiO2) were investigated to elucidate their impact on POAF.Main results: Out of 441 enrolled individuals, a total of 192 participants developed POAF (43.5%). We observed that POAF patients received a higher peak driving pressure, and a higher peak respiration rate than non-POAF individuals. Within the multivariate regression model, plateau pressure (adjusted OR 1.199 [1.038–1.661], p = 0.019), driving pressure (adjusted OR 1.244 [1.103–1.713], p = 0.021), and peak respiration rate (adjusted OR 1.206 [1.005–1.601], p = 0.040) proved to be independently associated with the development of POAF. CART analysis revealed a cut-off of ≥17.5 cmH2O of plateau pressure, ≥11.5 cmH2O of driving pressure and ≥ 17 respirations per minute as high-risk for POAF development.Conclusions: The ventilatory settings of plateau pressure, driving pressure, and respiration rate after cardiac surgery influence POAF occurrence probability. Optimized postoperative care such as lung-protective ventilation and increased awareness towards postoperative ventilatory efforts should be considered to prevent POAF development and poor patient outcome.
abstract_unstemmed	Study objective: Postoperative atrial fibrillation (POAF) is a frequent complication after cardiac valve- or coronary artery bypass (CABG) surgery and is associated with increased mortality. While it is known that prolonged postoperative invasive ventilation triggers POAF, the impact of ventilatory settings on POAF development has not been studied yet.Design: Prospective observational study.Setting: Postoperative Intensive Care Unit.Patients: Patients having undergone elective CABG and/or cardiac valve surgery.Measurements: Screening for the development of POAF. Patients' clinical data and postoperative ventilatory settings (driving pressure, controlled pressure above positive endexpiratory pressure (PEEP), respiration rate, and FiO2) were investigated to elucidate their impact on POAF.Main results: Out of 441 enrolled individuals, a total of 192 participants developed POAF (43.5%). We observed that POAF patients received a higher peak driving pressure, and a higher peak respiration rate than non-POAF individuals. Within the multivariate regression model, plateau pressure (adjusted OR 1.199 [1.038–1.661], p = 0.019), driving pressure (adjusted OR 1.244 [1.103–1.713], p = 0.021), and peak respiration rate (adjusted OR 1.206 [1.005–1.601], p = 0.040) proved to be independently associated with the development of POAF. CART analysis revealed a cut-off of ≥17.5 cmH2O of plateau pressure, ≥11.5 cmH2O of driving pressure and ≥ 17 respirations per minute as high-risk for POAF development.Conclusions: The ventilatory settings of plateau pressure, driving pressure, and respiration rate after cardiac surgery influence POAF occurrence probability. Optimized postoperative care such as lung-protective ventilation and increased awareness towards postoperative ventilatory efforts should be considered to prevent POAF development and poor patient outcome.
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title_short	The impact of invasive respiratory support on the development of postoperative atrial fibrillation following cardiac surgery
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author2	Stajic, Alexander Koller, Lorenz Hofer, Felix Kazem, Niema Hammer, Andreas Andreas, Martin Laufer, Günther Steinlechner, Barbara Richter, Bernhard Niessner, Alexander Sulzgruber, Patrick
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up_date	2024-07-06T20:06:24.064Z
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While it is known that prolonged postoperative invasive ventilation triggers POAF, the impact of ventilatory settings on POAF development has not been studied yet.Design: Prospective observational study.Setting: Postoperative Intensive Care Unit.Patients: Patients having undergone elective CABG and/or cardiac valve surgery.Measurements: Screening for the development of POAF. Patients' clinical data and postoperative ventilatory settings (driving pressure, controlled pressure above positive endexpiratory pressure (PEEP), respiration rate, and FiO2) were investigated to elucidate their impact on POAF.Main results: Out of 441 enrolled individuals, a total of 192 participants developed POAF (43.5%). We observed that POAF patients received a higher peak driving pressure, and a higher peak respiration rate than non-POAF individuals. Within the multivariate regression model, plateau pressure (adjusted OR 1.199 [1.038–1.661], p = 0.019), driving pressure (adjusted OR 1.244 [1.103–1.713], p = 0.021), and peak respiration rate (adjusted OR 1.206 [1.005–1.601], p = 0.040) proved to be independently associated with the development of POAF. CART analysis revealed a cut-off of ≥17.5 cmH2O of plateau pressure, ≥11.5 cmH2O of driving pressure and ≥ 17 respirations per minute as high-risk for POAF development.Conclusions: The ventilatory settings of plateau pressure, driving pressure, and respiration rate after cardiac surgery influence POAF occurrence probability. Optimized postoperative care such as lung-protective ventilation and increased awareness towards postoperative ventilatory efforts should be considered to prevent POAF development and poor patient outcome.</subfield></datafield><datafield tag="650" ind1=" " ind2="4"><subfield code="a">Atrial fibrillation</subfield></datafield><datafield tag="650" ind1=" " ind2="4"><subfield code="a">Cardiac surgery</subfield></datafield><datafield tag="650" ind1=" " ind2="4"><subfield code="a">Ventilatory effort</subfield></datafield><datafield tag="650" ind1=" " ind2="4"><subfield code="a">Ventilatory settings</subfield></datafield><datafield tag="650" ind1=" " ind2="4"><subfield code="a">Invasive ventilation</subfield></datafield><datafield tag="700" ind1="1" ind2=" "><subfield code="a">Stajic, Alexander</subfield><subfield code="e">verfasserin</subfield><subfield code="4">aut</subfield></datafield><datafield tag="700" ind1="1" ind2=" "><subfield code="a">Koller, Lorenz</subfield><subfield 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The impact of invasive respiratory support on the development of postoperative atrial fibrillation following cardiac surgery

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