Ratiometric covalent organic framework florescence sensor for detecting hydrazine produced from isoniazid metabolism in cell

Designing luminescent COFs with high fluorescence quantum yield is always a huge challenge. In this work, we synthesized COF TzDha through Schiff base reaction between 4, 4′, 4′'-(1,3,5-triazine-2,4,6-triyl) trianiline (Tz) and 2,5-dihydroxyterephthalaldehyde (Dha), and post-modified COF TzDha-...
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Autor*in:	Cao, Yuping [verfasserIn] Zhang, Liang [verfasserIn] Yang, Jilu [verfasserIn] Zhang, Jin [verfasserIn] Si, Wenbo [verfasserIn] Wang, Jiemin [verfasserIn] Iqbal, Anam [verfasserIn] Qin, Wenwu [verfasserIn] Liu, Yun [verfasserIn]

Format:	E-Artikel
Sprache:	Englisch

Erschienen:	2021

Schlagwörter:	Covalent organic frameworks Fluorescence quantum yield Ratiometric sensor Isoniazid metabolism Hydrazine

Übergeordnetes Werk:	Enthalten in: Sensors and actuators / B - Amsterdam [u.a.] : Elsevier Science, 1990, 346
Übergeordnetes Werk:	volume:346

DOI / URN:	10.1016/j.snb.2021.130472

Katalog-ID:	ELV00653662X

Internformat


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245	1	0	\|a Ratiometric covalent organic framework florescence sensor for detecting hydrazine produced from isoniazid metabolism in cell
264		1	\|c 2021
336			\|a nicht spezifiziert \|b zzz \|2 rdacontent
337			\|a Computermedien \|b c \|2 rdamedia
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520			\|a Designing luminescent COFs with high fluorescence quantum yield is always a huge challenge. In this work, we synthesized COF TzDha through Schiff base reaction between 4, 4′, 4′'-(1,3,5-triazine-2,4,6-triyl) trianiline (Tz) and 2,5-dihydroxyterephthalaldehyde (Dha), and post-modified COF TzDha-AC was grafted by refluxing in acetic anhydride. TzDha-AC shows higher relative fluorescence quantum yield (Φf) in various organic solvents and water, which is approximately 1.35 to 5.31 times to TzDha. What’s more surprising, TzDha-AC shows excellent ratiometric effect when it is used to detecte hydrazine (N2H4). Detection mechanism is attributed to that hydrazine prevents the intramolecular charge transfer (ICT) from benzene ring to triazine ring of TzDha-AC, thus the emission blue shifted from 601 nm to 526 nm. The detection limit (DL) of N2H4 is calculated to be 0.038 mM in the linear range of 0−10 mM. In addition, we also use TzDha-AC to detecte hydrazine produced from isoniazid metabolism in mouse liver cells and find that TzDha-AC could be a new material employed for simple isoniazid metabolism in cell.
650		4	\|a Covalent organic frameworks
650		4	\|a Fluorescence quantum yield
650		4	\|a Ratiometric sensor
650		4	\|a Isoniazid metabolism
650		4	\|a Hydrazine
700	1		\|a Zhang, Liang \|e verfasserin \|4 aut
700	1		\|a Yang, Jilu \|e verfasserin \|4 aut
700	1		\|a Zhang, Jin \|e verfasserin \|4 aut
700	1		\|a Si, Wenbo \|e verfasserin \|4 aut
700	1		\|a Wang, Jiemin \|e verfasserin \|4 aut
700	1		\|a Iqbal, Anam \|e verfasserin \|4 aut
700	1		\|a Qin, Wenwu \|e verfasserin \|0 (orcid)0000-0002-9782-6647 \|4 aut
700	1		\|a Liu, Yun \|e verfasserin \|4 aut
773	0	8	\|i Enthalten in \|t Sensors and actuators <Lausanne> / B \|d Amsterdam [u.a.] : Elsevier Science, 1990 \|g 346 \|h Online-Ressource \|w (DE-627)306710358 \|w (DE-600)1500731-5 \|w (DE-576)082435855 \|x 0925-4005 \|7 nnns
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912			\|a GBV_ILN_2025
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912			\|a GBV_ILN_2034
912			\|a GBV_ILN_2038
912			\|a GBV_ILN_2044
912			\|a GBV_ILN_2048
912			\|a GBV_ILN_2049
912			\|a GBV_ILN_2050
912			\|a GBV_ILN_2056
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912			\|a GBV_ILN_2064
912			\|a GBV_ILN_2065
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912			\|a GBV_ILN_4305
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912			\|a GBV_ILN_4323
912			\|a GBV_ILN_4324
912			\|a GBV_ILN_4326
912			\|a GBV_ILN_4333
912			\|a GBV_ILN_4334
912			\|a GBV_ILN_4335
912			\|a GBV_ILN_4338
912			\|a GBV_ILN_4393
936	b	k	\|a 50.22 \|j Sensorik
936	b	k	\|a 35.07 \|j Chemisches Labor \|j chemische Methoden
951			\|a AR
952			\|d 346

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author_variant	y c yc l z lz j y jy j z jz w s ws j w jw a i ai w q wq y l yl
matchkey_str	article:09254005:2021----::aimticvlnogncrmwrfoecneesrodtcigyrznpoue
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allfields	10.1016/j.snb.2021.130472 doi (DE-627)ELV00653662X (ELSEVIER)S0925-4005(21)01040-6 DE-627 ger DE-627 rda eng 530 620 DE-600 50.22 bkl 35.07 bkl Cao, Yuping verfasserin aut Ratiometric covalent organic framework florescence sensor for detecting hydrazine produced from isoniazid metabolism in cell 2021 nicht spezifiziert zzz rdacontent Computermedien c rdamedia Online-Ressource cr rdacarrier Designing luminescent COFs with high fluorescence quantum yield is always a huge challenge. In this work, we synthesized COF TzDha through Schiff base reaction between 4, 4′, 4′'-(1,3,5-triazine-2,4,6-triyl) trianiline (Tz) and 2,5-dihydroxyterephthalaldehyde (Dha), and post-modified COF TzDha-AC was grafted by refluxing in acetic anhydride. TzDha-AC shows higher relative fluorescence quantum yield (Φf) in various organic solvents and water, which is approximately 1.35 to 5.31 times to TzDha. What’s more surprising, TzDha-AC shows excellent ratiometric effect when it is used to detecte hydrazine (N2H4). Detection mechanism is attributed to that hydrazine prevents the intramolecular charge transfer (ICT) from benzene ring to triazine ring of TzDha-AC, thus the emission blue shifted from 601 nm to 526 nm. The detection limit (DL) of N2H4 is calculated to be 0.038 mM in the linear range of 0−10 mM. In addition, we also use TzDha-AC to detecte hydrazine produced from isoniazid metabolism in mouse liver cells and find that TzDha-AC could be a new material employed for simple isoniazid metabolism in cell. Covalent organic frameworks Fluorescence quantum yield Ratiometric sensor Isoniazid metabolism Hydrazine Zhang, Liang verfasserin aut Yang, Jilu verfasserin aut Zhang, Jin verfasserin aut Si, Wenbo verfasserin aut Wang, Jiemin verfasserin aut Iqbal, Anam verfasserin aut Qin, Wenwu verfasserin (orcid)0000-0002-9782-6647 aut Liu, Yun verfasserin aut Enthalten in Sensors and actuators <Lausanne> / B Amsterdam [u.a.] : Elsevier Science, 1990 346 Online-Ressource (DE-627)306710358 (DE-600)1500731-5 (DE-576)082435855 0925-4005 nnns volume:346 GBV_USEFLAG_U SYSFLAG_U GBV_ELV SSG-OLC-PHA GBV_ILN_20 GBV_ILN_22 GBV_ILN_23 GBV_ILN_24 GBV_ILN_31 GBV_ILN_32 GBV_ILN_40 GBV_ILN_60 GBV_ILN_62 GBV_ILN_63 GBV_ILN_65 GBV_ILN_69 GBV_ILN_70 GBV_ILN_73 GBV_ILN_74 GBV_ILN_90 GBV_ILN_95 GBV_ILN_100 GBV_ILN_101 GBV_ILN_105 GBV_ILN_110 GBV_ILN_150 GBV_ILN_151 GBV_ILN_224 GBV_ILN_370 GBV_ILN_602 GBV_ILN_702 GBV_ILN_2003 GBV_ILN_2004 GBV_ILN_2005 GBV_ILN_2011 GBV_ILN_2014 GBV_ILN_2015 GBV_ILN_2020 GBV_ILN_2021 GBV_ILN_2025 GBV_ILN_2027 GBV_ILN_2034 GBV_ILN_2038 GBV_ILN_2044 GBV_ILN_2048 GBV_ILN_2049 GBV_ILN_2050 GBV_ILN_2056 GBV_ILN_2059 GBV_ILN_2061 GBV_ILN_2064 GBV_ILN_2065 GBV_ILN_2068 GBV_ILN_2111 GBV_ILN_2112 GBV_ILN_2113 GBV_ILN_2118 GBV_ILN_2122 GBV_ILN_2129 GBV_ILN_2143 GBV_ILN_2147 GBV_ILN_2148 GBV_ILN_2152 GBV_ILN_2153 GBV_ILN_2190 GBV_ILN_2336 GBV_ILN_2507 GBV_ILN_2522 GBV_ILN_4035 GBV_ILN_4037 GBV_ILN_4112 GBV_ILN_4125 GBV_ILN_4126 GBV_ILN_4242 GBV_ILN_4251 GBV_ILN_4305 GBV_ILN_4313 GBV_ILN_4323 GBV_ILN_4324 GBV_ILN_4326 GBV_ILN_4333 GBV_ILN_4334 GBV_ILN_4335 GBV_ILN_4338 GBV_ILN_4393 50.22 Sensorik 35.07 Chemisches Labor chemische Methoden AR 346
spelling	10.1016/j.snb.2021.130472 doi (DE-627)ELV00653662X (ELSEVIER)S0925-4005(21)01040-6 DE-627 ger DE-627 rda eng 530 620 DE-600 50.22 bkl 35.07 bkl Cao, Yuping verfasserin aut Ratiometric covalent organic framework florescence sensor for detecting hydrazine produced from isoniazid metabolism in cell 2021 nicht spezifiziert zzz rdacontent Computermedien c rdamedia Online-Ressource cr rdacarrier Designing luminescent COFs with high fluorescence quantum yield is always a huge challenge. In this work, we synthesized COF TzDha through Schiff base reaction between 4, 4′, 4′'-(1,3,5-triazine-2,4,6-triyl) trianiline (Tz) and 2,5-dihydroxyterephthalaldehyde (Dha), and post-modified COF TzDha-AC was grafted by refluxing in acetic anhydride. TzDha-AC shows higher relative fluorescence quantum yield (Φf) in various organic solvents and water, which is approximately 1.35 to 5.31 times to TzDha. What’s more surprising, TzDha-AC shows excellent ratiometric effect when it is used to detecte hydrazine (N2H4). Detection mechanism is attributed to that hydrazine prevents the intramolecular charge transfer (ICT) from benzene ring to triazine ring of TzDha-AC, thus the emission blue shifted from 601 nm to 526 nm. The detection limit (DL) of N2H4 is calculated to be 0.038 mM in the linear range of 0−10 mM. In addition, we also use TzDha-AC to detecte hydrazine produced from isoniazid metabolism in mouse liver cells and find that TzDha-AC could be a new material employed for simple isoniazid metabolism in cell. Covalent organic frameworks Fluorescence quantum yield Ratiometric sensor Isoniazid metabolism Hydrazine Zhang, Liang verfasserin aut Yang, Jilu verfasserin aut Zhang, Jin verfasserin aut Si, Wenbo verfasserin aut Wang, Jiemin verfasserin aut Iqbal, Anam verfasserin aut Qin, Wenwu verfasserin (orcid)0000-0002-9782-6647 aut Liu, Yun verfasserin aut Enthalten in Sensors and actuators <Lausanne> / B Amsterdam [u.a.] : Elsevier Science, 1990 346 Online-Ressource (DE-627)306710358 (DE-600)1500731-5 (DE-576)082435855 0925-4005 nnns volume:346 GBV_USEFLAG_U SYSFLAG_U GBV_ELV SSG-OLC-PHA GBV_ILN_20 GBV_ILN_22 GBV_ILN_23 GBV_ILN_24 GBV_ILN_31 GBV_ILN_32 GBV_ILN_40 GBV_ILN_60 GBV_ILN_62 GBV_ILN_63 GBV_ILN_65 GBV_ILN_69 GBV_ILN_70 GBV_ILN_73 GBV_ILN_74 GBV_ILN_90 GBV_ILN_95 GBV_ILN_100 GBV_ILN_101 GBV_ILN_105 GBV_ILN_110 GBV_ILN_150 GBV_ILN_151 GBV_ILN_224 GBV_ILN_370 GBV_ILN_602 GBV_ILN_702 GBV_ILN_2003 GBV_ILN_2004 GBV_ILN_2005 GBV_ILN_2011 GBV_ILN_2014 GBV_ILN_2015 GBV_ILN_2020 GBV_ILN_2021 GBV_ILN_2025 GBV_ILN_2027 GBV_ILN_2034 GBV_ILN_2038 GBV_ILN_2044 GBV_ILN_2048 GBV_ILN_2049 GBV_ILN_2050 GBV_ILN_2056 GBV_ILN_2059 GBV_ILN_2061 GBV_ILN_2064 GBV_ILN_2065 GBV_ILN_2068 GBV_ILN_2111 GBV_ILN_2112 GBV_ILN_2113 GBV_ILN_2118 GBV_ILN_2122 GBV_ILN_2129 GBV_ILN_2143 GBV_ILN_2147 GBV_ILN_2148 GBV_ILN_2152 GBV_ILN_2153 GBV_ILN_2190 GBV_ILN_2336 GBV_ILN_2507 GBV_ILN_2522 GBV_ILN_4035 GBV_ILN_4037 GBV_ILN_4112 GBV_ILN_4125 GBV_ILN_4126 GBV_ILN_4242 GBV_ILN_4251 GBV_ILN_4305 GBV_ILN_4313 GBV_ILN_4323 GBV_ILN_4324 GBV_ILN_4326 GBV_ILN_4333 GBV_ILN_4334 GBV_ILN_4335 GBV_ILN_4338 GBV_ILN_4393 50.22 Sensorik 35.07 Chemisches Labor chemische Methoden AR 346
allfields_unstemmed	10.1016/j.snb.2021.130472 doi (DE-627)ELV00653662X (ELSEVIER)S0925-4005(21)01040-6 DE-627 ger DE-627 rda eng 530 620 DE-600 50.22 bkl 35.07 bkl Cao, Yuping verfasserin aut Ratiometric covalent organic framework florescence sensor for detecting hydrazine produced from isoniazid metabolism in cell 2021 nicht spezifiziert zzz rdacontent Computermedien c rdamedia Online-Ressource cr rdacarrier Designing luminescent COFs with high fluorescence quantum yield is always a huge challenge. In this work, we synthesized COF TzDha through Schiff base reaction between 4, 4′, 4′'-(1,3,5-triazine-2,4,6-triyl) trianiline (Tz) and 2,5-dihydroxyterephthalaldehyde (Dha), and post-modified COF TzDha-AC was grafted by refluxing in acetic anhydride. TzDha-AC shows higher relative fluorescence quantum yield (Φf) in various organic solvents and water, which is approximately 1.35 to 5.31 times to TzDha. What’s more surprising, TzDha-AC shows excellent ratiometric effect when it is used to detecte hydrazine (N2H4). Detection mechanism is attributed to that hydrazine prevents the intramolecular charge transfer (ICT) from benzene ring to triazine ring of TzDha-AC, thus the emission blue shifted from 601 nm to 526 nm. The detection limit (DL) of N2H4 is calculated to be 0.038 mM in the linear range of 0−10 mM. In addition, we also use TzDha-AC to detecte hydrazine produced from isoniazid metabolism in mouse liver cells and find that TzDha-AC could be a new material employed for simple isoniazid metabolism in cell. Covalent organic frameworks Fluorescence quantum yield Ratiometric sensor Isoniazid metabolism Hydrazine Zhang, Liang verfasserin aut Yang, Jilu verfasserin aut Zhang, Jin verfasserin aut Si, Wenbo verfasserin aut Wang, Jiemin verfasserin aut Iqbal, Anam verfasserin aut Qin, Wenwu verfasserin (orcid)0000-0002-9782-6647 aut Liu, Yun verfasserin aut Enthalten in Sensors and actuators <Lausanne> / B Amsterdam [u.a.] : Elsevier Science, 1990 346 Online-Ressource (DE-627)306710358 (DE-600)1500731-5 (DE-576)082435855 0925-4005 nnns volume:346 GBV_USEFLAG_U SYSFLAG_U GBV_ELV SSG-OLC-PHA GBV_ILN_20 GBV_ILN_22 GBV_ILN_23 GBV_ILN_24 GBV_ILN_31 GBV_ILN_32 GBV_ILN_40 GBV_ILN_60 GBV_ILN_62 GBV_ILN_63 GBV_ILN_65 GBV_ILN_69 GBV_ILN_70 GBV_ILN_73 GBV_ILN_74 GBV_ILN_90 GBV_ILN_95 GBV_ILN_100 GBV_ILN_101 GBV_ILN_105 GBV_ILN_110 GBV_ILN_150 GBV_ILN_151 GBV_ILN_224 GBV_ILN_370 GBV_ILN_602 GBV_ILN_702 GBV_ILN_2003 GBV_ILN_2004 GBV_ILN_2005 GBV_ILN_2011 GBV_ILN_2014 GBV_ILN_2015 GBV_ILN_2020 GBV_ILN_2021 GBV_ILN_2025 GBV_ILN_2027 GBV_ILN_2034 GBV_ILN_2038 GBV_ILN_2044 GBV_ILN_2048 GBV_ILN_2049 GBV_ILN_2050 GBV_ILN_2056 GBV_ILN_2059 GBV_ILN_2061 GBV_ILN_2064 GBV_ILN_2065 GBV_ILN_2068 GBV_ILN_2111 GBV_ILN_2112 GBV_ILN_2113 GBV_ILN_2118 GBV_ILN_2122 GBV_ILN_2129 GBV_ILN_2143 GBV_ILN_2147 GBV_ILN_2148 GBV_ILN_2152 GBV_ILN_2153 GBV_ILN_2190 GBV_ILN_2336 GBV_ILN_2507 GBV_ILN_2522 GBV_ILN_4035 GBV_ILN_4037 GBV_ILN_4112 GBV_ILN_4125 GBV_ILN_4126 GBV_ILN_4242 GBV_ILN_4251 GBV_ILN_4305 GBV_ILN_4313 GBV_ILN_4323 GBV_ILN_4324 GBV_ILN_4326 GBV_ILN_4333 GBV_ILN_4334 GBV_ILN_4335 GBV_ILN_4338 GBV_ILN_4393 50.22 Sensorik 35.07 Chemisches Labor chemische Methoden AR 346
allfieldsGer	10.1016/j.snb.2021.130472 doi (DE-627)ELV00653662X (ELSEVIER)S0925-4005(21)01040-6 DE-627 ger DE-627 rda eng 530 620 DE-600 50.22 bkl 35.07 bkl Cao, Yuping verfasserin aut Ratiometric covalent organic framework florescence sensor for detecting hydrazine produced from isoniazid metabolism in cell 2021 nicht spezifiziert zzz rdacontent Computermedien c rdamedia Online-Ressource cr rdacarrier Designing luminescent COFs with high fluorescence quantum yield is always a huge challenge. In this work, we synthesized COF TzDha through Schiff base reaction between 4, 4′, 4′'-(1,3,5-triazine-2,4,6-triyl) trianiline (Tz) and 2,5-dihydroxyterephthalaldehyde (Dha), and post-modified COF TzDha-AC was grafted by refluxing in acetic anhydride. TzDha-AC shows higher relative fluorescence quantum yield (Φf) in various organic solvents and water, which is approximately 1.35 to 5.31 times to TzDha. What’s more surprising, TzDha-AC shows excellent ratiometric effect when it is used to detecte hydrazine (N2H4). Detection mechanism is attributed to that hydrazine prevents the intramolecular charge transfer (ICT) from benzene ring to triazine ring of TzDha-AC, thus the emission blue shifted from 601 nm to 526 nm. The detection limit (DL) of N2H4 is calculated to be 0.038 mM in the linear range of 0−10 mM. In addition, we also use TzDha-AC to detecte hydrazine produced from isoniazid metabolism in mouse liver cells and find that TzDha-AC could be a new material employed for simple isoniazid metabolism in cell. Covalent organic frameworks Fluorescence quantum yield Ratiometric sensor Isoniazid metabolism Hydrazine Zhang, Liang verfasserin aut Yang, Jilu verfasserin aut Zhang, Jin verfasserin aut Si, Wenbo verfasserin aut Wang, Jiemin verfasserin aut Iqbal, Anam verfasserin aut Qin, Wenwu verfasserin (orcid)0000-0002-9782-6647 aut Liu, Yun verfasserin aut Enthalten in Sensors and actuators <Lausanne> / B Amsterdam [u.a.] : Elsevier Science, 1990 346 Online-Ressource (DE-627)306710358 (DE-600)1500731-5 (DE-576)082435855 0925-4005 nnns volume:346 GBV_USEFLAG_U SYSFLAG_U GBV_ELV SSG-OLC-PHA GBV_ILN_20 GBV_ILN_22 GBV_ILN_23 GBV_ILN_24 GBV_ILN_31 GBV_ILN_32 GBV_ILN_40 GBV_ILN_60 GBV_ILN_62 GBV_ILN_63 GBV_ILN_65 GBV_ILN_69 GBV_ILN_70 GBV_ILN_73 GBV_ILN_74 GBV_ILN_90 GBV_ILN_95 GBV_ILN_100 GBV_ILN_101 GBV_ILN_105 GBV_ILN_110 GBV_ILN_150 GBV_ILN_151 GBV_ILN_224 GBV_ILN_370 GBV_ILN_602 GBV_ILN_702 GBV_ILN_2003 GBV_ILN_2004 GBV_ILN_2005 GBV_ILN_2011 GBV_ILN_2014 GBV_ILN_2015 GBV_ILN_2020 GBV_ILN_2021 GBV_ILN_2025 GBV_ILN_2027 GBV_ILN_2034 GBV_ILN_2038 GBV_ILN_2044 GBV_ILN_2048 GBV_ILN_2049 GBV_ILN_2050 GBV_ILN_2056 GBV_ILN_2059 GBV_ILN_2061 GBV_ILN_2064 GBV_ILN_2065 GBV_ILN_2068 GBV_ILN_2111 GBV_ILN_2112 GBV_ILN_2113 GBV_ILN_2118 GBV_ILN_2122 GBV_ILN_2129 GBV_ILN_2143 GBV_ILN_2147 GBV_ILN_2148 GBV_ILN_2152 GBV_ILN_2153 GBV_ILN_2190 GBV_ILN_2336 GBV_ILN_2507 GBV_ILN_2522 GBV_ILN_4035 GBV_ILN_4037 GBV_ILN_4112 GBV_ILN_4125 GBV_ILN_4126 GBV_ILN_4242 GBV_ILN_4251 GBV_ILN_4305 GBV_ILN_4313 GBV_ILN_4323 GBV_ILN_4324 GBV_ILN_4326 GBV_ILN_4333 GBV_ILN_4334 GBV_ILN_4335 GBV_ILN_4338 GBV_ILN_4393 50.22 Sensorik 35.07 Chemisches Labor chemische Methoden AR 346
allfieldsSound	10.1016/j.snb.2021.130472 doi (DE-627)ELV00653662X (ELSEVIER)S0925-4005(21)01040-6 DE-627 ger DE-627 rda eng 530 620 DE-600 50.22 bkl 35.07 bkl Cao, Yuping verfasserin aut Ratiometric covalent organic framework florescence sensor for detecting hydrazine produced from isoniazid metabolism in cell 2021 nicht spezifiziert zzz rdacontent Computermedien c rdamedia Online-Ressource cr rdacarrier Designing luminescent COFs with high fluorescence quantum yield is always a huge challenge. In this work, we synthesized COF TzDha through Schiff base reaction between 4, 4′, 4′'-(1,3,5-triazine-2,4,6-triyl) trianiline (Tz) and 2,5-dihydroxyterephthalaldehyde (Dha), and post-modified COF TzDha-AC was grafted by refluxing in acetic anhydride. TzDha-AC shows higher relative fluorescence quantum yield (Φf) in various organic solvents and water, which is approximately 1.35 to 5.31 times to TzDha. What’s more surprising, TzDha-AC shows excellent ratiometric effect when it is used to detecte hydrazine (N2H4). Detection mechanism is attributed to that hydrazine prevents the intramolecular charge transfer (ICT) from benzene ring to triazine ring of TzDha-AC, thus the emission blue shifted from 601 nm to 526 nm. The detection limit (DL) of N2H4 is calculated to be 0.038 mM in the linear range of 0−10 mM. In addition, we also use TzDha-AC to detecte hydrazine produced from isoniazid metabolism in mouse liver cells and find that TzDha-AC could be a new material employed for simple isoniazid metabolism in cell. Covalent organic frameworks Fluorescence quantum yield Ratiometric sensor Isoniazid metabolism Hydrazine Zhang, Liang verfasserin aut Yang, Jilu verfasserin aut Zhang, Jin verfasserin aut Si, Wenbo verfasserin aut Wang, Jiemin verfasserin aut Iqbal, Anam verfasserin aut Qin, Wenwu verfasserin (orcid)0000-0002-9782-6647 aut Liu, Yun verfasserin aut Enthalten in Sensors and actuators <Lausanne> / B Amsterdam [u.a.] : Elsevier Science, 1990 346 Online-Ressource (DE-627)306710358 (DE-600)1500731-5 (DE-576)082435855 0925-4005 nnns volume:346 GBV_USEFLAG_U SYSFLAG_U GBV_ELV SSG-OLC-PHA GBV_ILN_20 GBV_ILN_22 GBV_ILN_23 GBV_ILN_24 GBV_ILN_31 GBV_ILN_32 GBV_ILN_40 GBV_ILN_60 GBV_ILN_62 GBV_ILN_63 GBV_ILN_65 GBV_ILN_69 GBV_ILN_70 GBV_ILN_73 GBV_ILN_74 GBV_ILN_90 GBV_ILN_95 GBV_ILN_100 GBV_ILN_101 GBV_ILN_105 GBV_ILN_110 GBV_ILN_150 GBV_ILN_151 GBV_ILN_224 GBV_ILN_370 GBV_ILN_602 GBV_ILN_702 GBV_ILN_2003 GBV_ILN_2004 GBV_ILN_2005 GBV_ILN_2011 GBV_ILN_2014 GBV_ILN_2015 GBV_ILN_2020 GBV_ILN_2021 GBV_ILN_2025 GBV_ILN_2027 GBV_ILN_2034 GBV_ILN_2038 GBV_ILN_2044 GBV_ILN_2048 GBV_ILN_2049 GBV_ILN_2050 GBV_ILN_2056 GBV_ILN_2059 GBV_ILN_2061 GBV_ILN_2064 GBV_ILN_2065 GBV_ILN_2068 GBV_ILN_2111 GBV_ILN_2112 GBV_ILN_2113 GBV_ILN_2118 GBV_ILN_2122 GBV_ILN_2129 GBV_ILN_2143 GBV_ILN_2147 GBV_ILN_2148 GBV_ILN_2152 GBV_ILN_2153 GBV_ILN_2190 GBV_ILN_2336 GBV_ILN_2507 GBV_ILN_2522 GBV_ILN_4035 GBV_ILN_4037 GBV_ILN_4112 GBV_ILN_4125 GBV_ILN_4126 GBV_ILN_4242 GBV_ILN_4251 GBV_ILN_4305 GBV_ILN_4313 GBV_ILN_4323 GBV_ILN_4324 GBV_ILN_4326 GBV_ILN_4333 GBV_ILN_4334 GBV_ILN_4335 GBV_ILN_4338 GBV_ILN_4393 50.22 Sensorik 35.07 Chemisches Labor chemische Methoden AR 346
language	English
source	Enthalten in Sensors and actuators <Lausanne> / B 346 volume:346
sourceStr	Enthalten in Sensors and actuators <Lausanne> / B 346 volume:346
format_phy_str_mv	Article
bklname	Sensorik Chemisches Labor chemische Methoden
institution	findex.gbv.de
topic_facet	Covalent organic frameworks Fluorescence quantum yield Ratiometric sensor Isoniazid metabolism Hydrazine
dewey-raw	530
isfreeaccess_bool	false
container_title	Sensors and actuators <Lausanne> / B
authorswithroles_txt_mv	Cao, Yuping @@aut@@ Zhang, Liang @@aut@@ Yang, Jilu @@aut@@ Zhang, Jin @@aut@@ Si, Wenbo @@aut@@ Wang, Jiemin @@aut@@ Iqbal, Anam @@aut@@ Qin, Wenwu @@aut@@ Liu, Yun @@aut@@
publishDateDaySort_date	2021-01-01T00:00:00Z
hierarchy_top_id	306710358
dewey-sort	3530
id	ELV00653662X
language_de	englisch
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author	Cao, Yuping
spellingShingle	Cao, Yuping ddc 530 bkl 50.22 bkl 35.07 misc Covalent organic frameworks misc Fluorescence quantum yield misc Ratiometric sensor misc Isoniazid metabolism misc Hydrazine Ratiometric covalent organic framework florescence sensor for detecting hydrazine produced from isoniazid metabolism in cell
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topic_title	530 620 DE-600 50.22 bkl 35.07 bkl Ratiometric covalent organic framework florescence sensor for detecting hydrazine produced from isoniazid metabolism in cell Covalent organic frameworks Fluorescence quantum yield Ratiometric sensor Isoniazid metabolism Hydrazine
topic	ddc 530 bkl 50.22 bkl 35.07 misc Covalent organic frameworks misc Fluorescence quantum yield misc Ratiometric sensor misc Isoniazid metabolism misc Hydrazine
topic_unstemmed	ddc 530 bkl 50.22 bkl 35.07 misc Covalent organic frameworks misc Fluorescence quantum yield misc Ratiometric sensor misc Isoniazid metabolism misc Hydrazine
topic_browse	ddc 530 bkl 50.22 bkl 35.07 misc Covalent organic frameworks misc Fluorescence quantum yield misc Ratiometric sensor misc Isoniazid metabolism misc Hydrazine
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title	Ratiometric covalent organic framework florescence sensor for detecting hydrazine produced from isoniazid metabolism in cell
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title_full	Ratiometric covalent organic framework florescence sensor for detecting hydrazine produced from isoniazid metabolism in cell
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author_browse	Cao, Yuping Zhang, Liang Yang, Jilu Zhang, Jin Si, Wenbo Wang, Jiemin Iqbal, Anam Qin, Wenwu Liu, Yun
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title_sort	ratiometric covalent organic framework florescence sensor for detecting hydrazine produced from isoniazid metabolism in cell
title_auth	Ratiometric covalent organic framework florescence sensor for detecting hydrazine produced from isoniazid metabolism in cell
abstract	Designing luminescent COFs with high fluorescence quantum yield is always a huge challenge. In this work, we synthesized COF TzDha through Schiff base reaction between 4, 4′, 4′'-(1,3,5-triazine-2,4,6-triyl) trianiline (Tz) and 2,5-dihydroxyterephthalaldehyde (Dha), and post-modified COF TzDha-AC was grafted by refluxing in acetic anhydride. TzDha-AC shows higher relative fluorescence quantum yield (Φf) in various organic solvents and water, which is approximately 1.35 to 5.31 times to TzDha. What’s more surprising, TzDha-AC shows excellent ratiometric effect when it is used to detecte hydrazine (N2H4). Detection mechanism is attributed to that hydrazine prevents the intramolecular charge transfer (ICT) from benzene ring to triazine ring of TzDha-AC, thus the emission blue shifted from 601 nm to 526 nm. The detection limit (DL) of N2H4 is calculated to be 0.038 mM in the linear range of 0−10 mM. In addition, we also use TzDha-AC to detecte hydrazine produced from isoniazid metabolism in mouse liver cells and find that TzDha-AC could be a new material employed for simple isoniazid metabolism in cell.
abstractGer	Designing luminescent COFs with high fluorescence quantum yield is always a huge challenge. In this work, we synthesized COF TzDha through Schiff base reaction between 4, 4′, 4′'-(1,3,5-triazine-2,4,6-triyl) trianiline (Tz) and 2,5-dihydroxyterephthalaldehyde (Dha), and post-modified COF TzDha-AC was grafted by refluxing in acetic anhydride. TzDha-AC shows higher relative fluorescence quantum yield (Φf) in various organic solvents and water, which is approximately 1.35 to 5.31 times to TzDha. What’s more surprising, TzDha-AC shows excellent ratiometric effect when it is used to detecte hydrazine (N2H4). Detection mechanism is attributed to that hydrazine prevents the intramolecular charge transfer (ICT) from benzene ring to triazine ring of TzDha-AC, thus the emission blue shifted from 601 nm to 526 nm. The detection limit (DL) of N2H4 is calculated to be 0.038 mM in the linear range of 0−10 mM. In addition, we also use TzDha-AC to detecte hydrazine produced from isoniazid metabolism in mouse liver cells and find that TzDha-AC could be a new material employed for simple isoniazid metabolism in cell.
abstract_unstemmed	Designing luminescent COFs with high fluorescence quantum yield is always a huge challenge. In this work, we synthesized COF TzDha through Schiff base reaction between 4, 4′, 4′'-(1,3,5-triazine-2,4,6-triyl) trianiline (Tz) and 2,5-dihydroxyterephthalaldehyde (Dha), and post-modified COF TzDha-AC was grafted by refluxing in acetic anhydride. TzDha-AC shows higher relative fluorescence quantum yield (Φf) in various organic solvents and water, which is approximately 1.35 to 5.31 times to TzDha. What’s more surprising, TzDha-AC shows excellent ratiometric effect when it is used to detecte hydrazine (N2H4). Detection mechanism is attributed to that hydrazine prevents the intramolecular charge transfer (ICT) from benzene ring to triazine ring of TzDha-AC, thus the emission blue shifted from 601 nm to 526 nm. The detection limit (DL) of N2H4 is calculated to be 0.038 mM in the linear range of 0−10 mM. In addition, we also use TzDha-AC to detecte hydrazine produced from isoniazid metabolism in mouse liver cells and find that TzDha-AC could be a new material employed for simple isoniazid metabolism in cell.
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title_short	Ratiometric covalent organic framework florescence sensor for detecting hydrazine produced from isoniazid metabolism in cell
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author2	Zhang, Liang Yang, Jilu Zhang, Jin Si, Wenbo Wang, Jiemin Iqbal, Anam Qin, Wenwu Liu, Yun
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up_date	2024-07-06T21:43:05.632Z
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Ratiometric covalent organic framework florescence sensor for detecting hydrazine produced from isoniazid metabolism in cell

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