A case series of acute pericarditis following COVID-19 vaccination in the context of recent reports from Europe and the United States
Background: COVID-19 vaccines were efficacious and safe in clinical trials. We report nine events of acute pericarditis (AP) in eight patients following COVID-19 vaccination with BNT162b2 (6/9), AZD1222 (2/9) and mRNA-1273 (1/9).Methods: All patients were referred for AP temporally linked with COVID...
Ausführliche Beschreibung
Autor*in: |
Lazaros, George [verfasserIn] Anastassopoulou, Cleo [verfasserIn] Hatziantoniou, Sophia [verfasserIn] Kalos, Theodoros [verfasserIn] Soulaidopoulos, Stergios [verfasserIn] Lazarou, Emilia [verfasserIn] Vlachopoulos, Charalambos [verfasserIn] Vassilopoulos, Dimitrios [verfasserIn] Tsakris, Athanasios [verfasserIn] Tsioufis, Costas [verfasserIn] |
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E-Artikel |
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Sprache: |
Englisch |
Erschienen: |
2021 |
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Schlagwörter: |
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Übergeordnetes Werk: |
Enthalten in: Vaccine - Amsterdam : Elsevier, 1983, 39, Seite 6585-6590 |
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Übergeordnetes Werk: |
volume:39 ; pages:6585-6590 |
DOI / URN: |
10.1016/j.vaccine.2021.09.078 |
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Katalog-ID: |
ELV006784747 |
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245 | 1 | 0 | |a A case series of acute pericarditis following COVID-19 vaccination in the context of recent reports from Europe and the United States |
264 | 1 | |c 2021 | |
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520 | |a Background: COVID-19 vaccines were efficacious and safe in clinical trials. We report nine events of acute pericarditis (AP) in eight patients following COVID-19 vaccination with BNT162b2 (6/9), AZD1222 (2/9) and mRNA-1273 (1/9).Methods: All patients were referred for AP temporally linked with COVID-19 vaccination. Chest pain was the most common clinical manifestation. Alternative etiologies were excluded upon thorough diagnostic work up. AP diagnosis was established according to ESC guidelines.Findings: Five events occurred after the first vaccine dose and four after the second. The mean age in this cohort was 65.8 ± 10.2 years and the men/women ratio 3/5. All events resolved without sequelae; two events were complicated by cardiac tamponade requiring emergent pericardial decompression. Hospitalization was required in four cases.Interpretation: Although causality cannot be firmly established, AP has emerged as a possible complication following COVID-19 vaccination. Further investigation is indispensable to fully characterize this new entity. | ||
650 | 4 | |a COVID-19 vaccination | |
650 | 4 | |a Pericarditis | |
650 | 4 | |a mRNA vaccines | |
650 | 4 | |a Adenovirus vector-based vaccines | |
650 | 4 | |a SARS-CoV-2, outcome | |
700 | 1 | |a Anastassopoulou, Cleo |e verfasserin |0 (orcid)0000-0001-7666-9198 |4 aut | |
700 | 1 | |a Hatziantoniou, Sophia |e verfasserin |4 aut | |
700 | 1 | |a Kalos, Theodoros |e verfasserin |4 aut | |
700 | 1 | |a Soulaidopoulos, Stergios |e verfasserin |4 aut | |
700 | 1 | |a Lazarou, Emilia |e verfasserin |4 aut | |
700 | 1 | |a Vlachopoulos, Charalambos |e verfasserin |4 aut | |
700 | 1 | |a Vassilopoulos, Dimitrios |e verfasserin |4 aut | |
700 | 1 | |a Tsakris, Athanasios |e verfasserin |4 aut | |
700 | 1 | |a Tsioufis, Costas |e verfasserin |4 aut | |
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allfields |
10.1016/j.vaccine.2021.09.078 doi (DE-627)ELV006784747 (ELSEVIER)S0264-410X(21)01295-0 DE-627 ger DE-627 rda eng 610 DE-600 44.45 bkl Lazaros, George verfasserin aut A case series of acute pericarditis following COVID-19 vaccination in the context of recent reports from Europe and the United States 2021 nicht spezifiziert zzz rdacontent Computermedien c rdamedia Online-Ressource cr rdacarrier Background: COVID-19 vaccines were efficacious and safe in clinical trials. We report nine events of acute pericarditis (AP) in eight patients following COVID-19 vaccination with BNT162b2 (6/9), AZD1222 (2/9) and mRNA-1273 (1/9).Methods: All patients were referred for AP temporally linked with COVID-19 vaccination. Chest pain was the most common clinical manifestation. Alternative etiologies were excluded upon thorough diagnostic work up. AP diagnosis was established according to ESC guidelines.Findings: Five events occurred after the first vaccine dose and four after the second. The mean age in this cohort was 65.8 ± 10.2 years and the men/women ratio 3/5. All events resolved without sequelae; two events were complicated by cardiac tamponade requiring emergent pericardial decompression. Hospitalization was required in four cases.Interpretation: Although causality cannot be firmly established, AP has emerged as a possible complication following COVID-19 vaccination. Further investigation is indispensable to fully characterize this new entity. COVID-19 vaccination Pericarditis mRNA vaccines Adenovirus vector-based vaccines SARS-CoV-2, outcome Anastassopoulou, Cleo verfasserin (orcid)0000-0001-7666-9198 aut Hatziantoniou, Sophia verfasserin aut Kalos, Theodoros verfasserin aut Soulaidopoulos, Stergios verfasserin aut Lazarou, Emilia verfasserin aut Vlachopoulos, Charalambos verfasserin aut Vassilopoulos, Dimitrios verfasserin aut Tsakris, Athanasios verfasserin aut Tsioufis, Costas verfasserin aut Enthalten in Vaccine Amsterdam : Elsevier, 1983 39, Seite 6585-6590 Online-Ressource (DE-627)266886078 (DE-600)1468474-3 (DE-576)075961857 1873-2518 nnns volume:39 pages:6585-6590 GBV_USEFLAG_U SYSFLAG_U GBV_ELV GBV_ILN_20 GBV_ILN_22 GBV_ILN_23 GBV_ILN_24 GBV_ILN_31 GBV_ILN_32 GBV_ILN_40 GBV_ILN_60 GBV_ILN_62 GBV_ILN_63 GBV_ILN_65 GBV_ILN_69 GBV_ILN_70 GBV_ILN_73 GBV_ILN_74 GBV_ILN_90 GBV_ILN_95 GBV_ILN_100 GBV_ILN_101 GBV_ILN_105 GBV_ILN_110 GBV_ILN_151 GBV_ILN_224 GBV_ILN_252 GBV_ILN_370 GBV_ILN_602 GBV_ILN_702 GBV_ILN_2003 GBV_ILN_2004 GBV_ILN_2005 GBV_ILN_2011 GBV_ILN_2014 GBV_ILN_2015 GBV_ILN_2020 GBV_ILN_2021 GBV_ILN_2025 GBV_ILN_2027 GBV_ILN_2034 GBV_ILN_2038 GBV_ILN_2044 GBV_ILN_2048 GBV_ILN_2049 GBV_ILN_2050 GBV_ILN_2056 GBV_ILN_2059 GBV_ILN_2061 GBV_ILN_2064 GBV_ILN_2065 GBV_ILN_2068 GBV_ILN_2111 GBV_ILN_2112 GBV_ILN_2113 GBV_ILN_2118 GBV_ILN_2122 GBV_ILN_2129 GBV_ILN_2143 GBV_ILN_2147 GBV_ILN_2148 GBV_ILN_2152 GBV_ILN_2153 GBV_ILN_2190 GBV_ILN_2336 GBV_ILN_2507 GBV_ILN_2522 GBV_ILN_4035 GBV_ILN_4037 GBV_ILN_4112 GBV_ILN_4125 GBV_ILN_4126 GBV_ILN_4242 GBV_ILN_4251 GBV_ILN_4305 GBV_ILN_4313 GBV_ILN_4323 GBV_ILN_4324 GBV_ILN_4325 GBV_ILN_4326 GBV_ILN_4333 GBV_ILN_4334 GBV_ILN_4335 GBV_ILN_4338 GBV_ILN_4393 44.45 Immunologie AR 39 6585-6590 |
spelling |
10.1016/j.vaccine.2021.09.078 doi (DE-627)ELV006784747 (ELSEVIER)S0264-410X(21)01295-0 DE-627 ger DE-627 rda eng 610 DE-600 44.45 bkl Lazaros, George verfasserin aut A case series of acute pericarditis following COVID-19 vaccination in the context of recent reports from Europe and the United States 2021 nicht spezifiziert zzz rdacontent Computermedien c rdamedia Online-Ressource cr rdacarrier Background: COVID-19 vaccines were efficacious and safe in clinical trials. We report nine events of acute pericarditis (AP) in eight patients following COVID-19 vaccination with BNT162b2 (6/9), AZD1222 (2/9) and mRNA-1273 (1/9).Methods: All patients were referred for AP temporally linked with COVID-19 vaccination. Chest pain was the most common clinical manifestation. Alternative etiologies were excluded upon thorough diagnostic work up. AP diagnosis was established according to ESC guidelines.Findings: Five events occurred after the first vaccine dose and four after the second. The mean age in this cohort was 65.8 ± 10.2 years and the men/women ratio 3/5. All events resolved without sequelae; two events were complicated by cardiac tamponade requiring emergent pericardial decompression. Hospitalization was required in four cases.Interpretation: Although causality cannot be firmly established, AP has emerged as a possible complication following COVID-19 vaccination. Further investigation is indispensable to fully characterize this new entity. COVID-19 vaccination Pericarditis mRNA vaccines Adenovirus vector-based vaccines SARS-CoV-2, outcome Anastassopoulou, Cleo verfasserin (orcid)0000-0001-7666-9198 aut Hatziantoniou, Sophia verfasserin aut Kalos, Theodoros verfasserin aut Soulaidopoulos, Stergios verfasserin aut Lazarou, Emilia verfasserin aut Vlachopoulos, Charalambos verfasserin aut Vassilopoulos, Dimitrios verfasserin aut Tsakris, Athanasios verfasserin aut Tsioufis, Costas verfasserin aut Enthalten in Vaccine Amsterdam : Elsevier, 1983 39, Seite 6585-6590 Online-Ressource (DE-627)266886078 (DE-600)1468474-3 (DE-576)075961857 1873-2518 nnns volume:39 pages:6585-6590 GBV_USEFLAG_U SYSFLAG_U GBV_ELV GBV_ILN_20 GBV_ILN_22 GBV_ILN_23 GBV_ILN_24 GBV_ILN_31 GBV_ILN_32 GBV_ILN_40 GBV_ILN_60 GBV_ILN_62 GBV_ILN_63 GBV_ILN_65 GBV_ILN_69 GBV_ILN_70 GBV_ILN_73 GBV_ILN_74 GBV_ILN_90 GBV_ILN_95 GBV_ILN_100 GBV_ILN_101 GBV_ILN_105 GBV_ILN_110 GBV_ILN_151 GBV_ILN_224 GBV_ILN_252 GBV_ILN_370 GBV_ILN_602 GBV_ILN_702 GBV_ILN_2003 GBV_ILN_2004 GBV_ILN_2005 GBV_ILN_2011 GBV_ILN_2014 GBV_ILN_2015 GBV_ILN_2020 GBV_ILN_2021 GBV_ILN_2025 GBV_ILN_2027 GBV_ILN_2034 GBV_ILN_2038 GBV_ILN_2044 GBV_ILN_2048 GBV_ILN_2049 GBV_ILN_2050 GBV_ILN_2056 GBV_ILN_2059 GBV_ILN_2061 GBV_ILN_2064 GBV_ILN_2065 GBV_ILN_2068 GBV_ILN_2111 GBV_ILN_2112 GBV_ILN_2113 GBV_ILN_2118 GBV_ILN_2122 GBV_ILN_2129 GBV_ILN_2143 GBV_ILN_2147 GBV_ILN_2148 GBV_ILN_2152 GBV_ILN_2153 GBV_ILN_2190 GBV_ILN_2336 GBV_ILN_2507 GBV_ILN_2522 GBV_ILN_4035 GBV_ILN_4037 GBV_ILN_4112 GBV_ILN_4125 GBV_ILN_4126 GBV_ILN_4242 GBV_ILN_4251 GBV_ILN_4305 GBV_ILN_4313 GBV_ILN_4323 GBV_ILN_4324 GBV_ILN_4325 GBV_ILN_4326 GBV_ILN_4333 GBV_ILN_4334 GBV_ILN_4335 GBV_ILN_4338 GBV_ILN_4393 44.45 Immunologie AR 39 6585-6590 |
allfields_unstemmed |
10.1016/j.vaccine.2021.09.078 doi (DE-627)ELV006784747 (ELSEVIER)S0264-410X(21)01295-0 DE-627 ger DE-627 rda eng 610 DE-600 44.45 bkl Lazaros, George verfasserin aut A case series of acute pericarditis following COVID-19 vaccination in the context of recent reports from Europe and the United States 2021 nicht spezifiziert zzz rdacontent Computermedien c rdamedia Online-Ressource cr rdacarrier Background: COVID-19 vaccines were efficacious and safe in clinical trials. We report nine events of acute pericarditis (AP) in eight patients following COVID-19 vaccination with BNT162b2 (6/9), AZD1222 (2/9) and mRNA-1273 (1/9).Methods: All patients were referred for AP temporally linked with COVID-19 vaccination. Chest pain was the most common clinical manifestation. Alternative etiologies were excluded upon thorough diagnostic work up. AP diagnosis was established according to ESC guidelines.Findings: Five events occurred after the first vaccine dose and four after the second. The mean age in this cohort was 65.8 ± 10.2 years and the men/women ratio 3/5. All events resolved without sequelae; two events were complicated by cardiac tamponade requiring emergent pericardial decompression. Hospitalization was required in four cases.Interpretation: Although causality cannot be firmly established, AP has emerged as a possible complication following COVID-19 vaccination. Further investigation is indispensable to fully characterize this new entity. COVID-19 vaccination Pericarditis mRNA vaccines Adenovirus vector-based vaccines SARS-CoV-2, outcome Anastassopoulou, Cleo verfasserin (orcid)0000-0001-7666-9198 aut Hatziantoniou, Sophia verfasserin aut Kalos, Theodoros verfasserin aut Soulaidopoulos, Stergios verfasserin aut Lazarou, Emilia verfasserin aut Vlachopoulos, Charalambos verfasserin aut Vassilopoulos, Dimitrios verfasserin aut Tsakris, Athanasios verfasserin aut Tsioufis, Costas verfasserin aut Enthalten in Vaccine Amsterdam : Elsevier, 1983 39, Seite 6585-6590 Online-Ressource (DE-627)266886078 (DE-600)1468474-3 (DE-576)075961857 1873-2518 nnns volume:39 pages:6585-6590 GBV_USEFLAG_U SYSFLAG_U GBV_ELV GBV_ILN_20 GBV_ILN_22 GBV_ILN_23 GBV_ILN_24 GBV_ILN_31 GBV_ILN_32 GBV_ILN_40 GBV_ILN_60 GBV_ILN_62 GBV_ILN_63 GBV_ILN_65 GBV_ILN_69 GBV_ILN_70 GBV_ILN_73 GBV_ILN_74 GBV_ILN_90 GBV_ILN_95 GBV_ILN_100 GBV_ILN_101 GBV_ILN_105 GBV_ILN_110 GBV_ILN_151 GBV_ILN_224 GBV_ILN_252 GBV_ILN_370 GBV_ILN_602 GBV_ILN_702 GBV_ILN_2003 GBV_ILN_2004 GBV_ILN_2005 GBV_ILN_2011 GBV_ILN_2014 GBV_ILN_2015 GBV_ILN_2020 GBV_ILN_2021 GBV_ILN_2025 GBV_ILN_2027 GBV_ILN_2034 GBV_ILN_2038 GBV_ILN_2044 GBV_ILN_2048 GBV_ILN_2049 GBV_ILN_2050 GBV_ILN_2056 GBV_ILN_2059 GBV_ILN_2061 GBV_ILN_2064 GBV_ILN_2065 GBV_ILN_2068 GBV_ILN_2111 GBV_ILN_2112 GBV_ILN_2113 GBV_ILN_2118 GBV_ILN_2122 GBV_ILN_2129 GBV_ILN_2143 GBV_ILN_2147 GBV_ILN_2148 GBV_ILN_2152 GBV_ILN_2153 GBV_ILN_2190 GBV_ILN_2336 GBV_ILN_2507 GBV_ILN_2522 GBV_ILN_4035 GBV_ILN_4037 GBV_ILN_4112 GBV_ILN_4125 GBV_ILN_4126 GBV_ILN_4242 GBV_ILN_4251 GBV_ILN_4305 GBV_ILN_4313 GBV_ILN_4323 GBV_ILN_4324 GBV_ILN_4325 GBV_ILN_4326 GBV_ILN_4333 GBV_ILN_4334 GBV_ILN_4335 GBV_ILN_4338 GBV_ILN_4393 44.45 Immunologie AR 39 6585-6590 |
allfieldsGer |
10.1016/j.vaccine.2021.09.078 doi (DE-627)ELV006784747 (ELSEVIER)S0264-410X(21)01295-0 DE-627 ger DE-627 rda eng 610 DE-600 44.45 bkl Lazaros, George verfasserin aut A case series of acute pericarditis following COVID-19 vaccination in the context of recent reports from Europe and the United States 2021 nicht spezifiziert zzz rdacontent Computermedien c rdamedia Online-Ressource cr rdacarrier Background: COVID-19 vaccines were efficacious and safe in clinical trials. We report nine events of acute pericarditis (AP) in eight patients following COVID-19 vaccination with BNT162b2 (6/9), AZD1222 (2/9) and mRNA-1273 (1/9).Methods: All patients were referred for AP temporally linked with COVID-19 vaccination. Chest pain was the most common clinical manifestation. Alternative etiologies were excluded upon thorough diagnostic work up. AP diagnosis was established according to ESC guidelines.Findings: Five events occurred after the first vaccine dose and four after the second. The mean age in this cohort was 65.8 ± 10.2 years and the men/women ratio 3/5. All events resolved without sequelae; two events were complicated by cardiac tamponade requiring emergent pericardial decompression. Hospitalization was required in four cases.Interpretation: Although causality cannot be firmly established, AP has emerged as a possible complication following COVID-19 vaccination. Further investigation is indispensable to fully characterize this new entity. COVID-19 vaccination Pericarditis mRNA vaccines Adenovirus vector-based vaccines SARS-CoV-2, outcome Anastassopoulou, Cleo verfasserin (orcid)0000-0001-7666-9198 aut Hatziantoniou, Sophia verfasserin aut Kalos, Theodoros verfasserin aut Soulaidopoulos, Stergios verfasserin aut Lazarou, Emilia verfasserin aut Vlachopoulos, Charalambos verfasserin aut Vassilopoulos, Dimitrios verfasserin aut Tsakris, Athanasios verfasserin aut Tsioufis, Costas verfasserin aut Enthalten in Vaccine Amsterdam : Elsevier, 1983 39, Seite 6585-6590 Online-Ressource (DE-627)266886078 (DE-600)1468474-3 (DE-576)075961857 1873-2518 nnns volume:39 pages:6585-6590 GBV_USEFLAG_U SYSFLAG_U GBV_ELV GBV_ILN_20 GBV_ILN_22 GBV_ILN_23 GBV_ILN_24 GBV_ILN_31 GBV_ILN_32 GBV_ILN_40 GBV_ILN_60 GBV_ILN_62 GBV_ILN_63 GBV_ILN_65 GBV_ILN_69 GBV_ILN_70 GBV_ILN_73 GBV_ILN_74 GBV_ILN_90 GBV_ILN_95 GBV_ILN_100 GBV_ILN_101 GBV_ILN_105 GBV_ILN_110 GBV_ILN_151 GBV_ILN_224 GBV_ILN_252 GBV_ILN_370 GBV_ILN_602 GBV_ILN_702 GBV_ILN_2003 GBV_ILN_2004 GBV_ILN_2005 GBV_ILN_2011 GBV_ILN_2014 GBV_ILN_2015 GBV_ILN_2020 GBV_ILN_2021 GBV_ILN_2025 GBV_ILN_2027 GBV_ILN_2034 GBV_ILN_2038 GBV_ILN_2044 GBV_ILN_2048 GBV_ILN_2049 GBV_ILN_2050 GBV_ILN_2056 GBV_ILN_2059 GBV_ILN_2061 GBV_ILN_2064 GBV_ILN_2065 GBV_ILN_2068 GBV_ILN_2111 GBV_ILN_2112 GBV_ILN_2113 GBV_ILN_2118 GBV_ILN_2122 GBV_ILN_2129 GBV_ILN_2143 GBV_ILN_2147 GBV_ILN_2148 GBV_ILN_2152 GBV_ILN_2153 GBV_ILN_2190 GBV_ILN_2336 GBV_ILN_2507 GBV_ILN_2522 GBV_ILN_4035 GBV_ILN_4037 GBV_ILN_4112 GBV_ILN_4125 GBV_ILN_4126 GBV_ILN_4242 GBV_ILN_4251 GBV_ILN_4305 GBV_ILN_4313 GBV_ILN_4323 GBV_ILN_4324 GBV_ILN_4325 GBV_ILN_4326 GBV_ILN_4333 GBV_ILN_4334 GBV_ILN_4335 GBV_ILN_4338 GBV_ILN_4393 44.45 Immunologie AR 39 6585-6590 |
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10.1016/j.vaccine.2021.09.078 doi (DE-627)ELV006784747 (ELSEVIER)S0264-410X(21)01295-0 DE-627 ger DE-627 rda eng 610 DE-600 44.45 bkl Lazaros, George verfasserin aut A case series of acute pericarditis following COVID-19 vaccination in the context of recent reports from Europe and the United States 2021 nicht spezifiziert zzz rdacontent Computermedien c rdamedia Online-Ressource cr rdacarrier Background: COVID-19 vaccines were efficacious and safe in clinical trials. We report nine events of acute pericarditis (AP) in eight patients following COVID-19 vaccination with BNT162b2 (6/9), AZD1222 (2/9) and mRNA-1273 (1/9).Methods: All patients were referred for AP temporally linked with COVID-19 vaccination. Chest pain was the most common clinical manifestation. Alternative etiologies were excluded upon thorough diagnostic work up. AP diagnosis was established according to ESC guidelines.Findings: Five events occurred after the first vaccine dose and four after the second. The mean age in this cohort was 65.8 ± 10.2 years and the men/women ratio 3/5. All events resolved without sequelae; two events were complicated by cardiac tamponade requiring emergent pericardial decompression. Hospitalization was required in four cases.Interpretation: Although causality cannot be firmly established, AP has emerged as a possible complication following COVID-19 vaccination. Further investigation is indispensable to fully characterize this new entity. COVID-19 vaccination Pericarditis mRNA vaccines Adenovirus vector-based vaccines SARS-CoV-2, outcome Anastassopoulou, Cleo verfasserin (orcid)0000-0001-7666-9198 aut Hatziantoniou, Sophia verfasserin aut Kalos, Theodoros verfasserin aut Soulaidopoulos, Stergios verfasserin aut Lazarou, Emilia verfasserin aut Vlachopoulos, Charalambos verfasserin aut Vassilopoulos, Dimitrios verfasserin aut Tsakris, Athanasios verfasserin aut Tsioufis, Costas verfasserin aut Enthalten in Vaccine Amsterdam : Elsevier, 1983 39, Seite 6585-6590 Online-Ressource (DE-627)266886078 (DE-600)1468474-3 (DE-576)075961857 1873-2518 nnns volume:39 pages:6585-6590 GBV_USEFLAG_U SYSFLAG_U GBV_ELV GBV_ILN_20 GBV_ILN_22 GBV_ILN_23 GBV_ILN_24 GBV_ILN_31 GBV_ILN_32 GBV_ILN_40 GBV_ILN_60 GBV_ILN_62 GBV_ILN_63 GBV_ILN_65 GBV_ILN_69 GBV_ILN_70 GBV_ILN_73 GBV_ILN_74 GBV_ILN_90 GBV_ILN_95 GBV_ILN_100 GBV_ILN_101 GBV_ILN_105 GBV_ILN_110 GBV_ILN_151 GBV_ILN_224 GBV_ILN_252 GBV_ILN_370 GBV_ILN_602 GBV_ILN_702 GBV_ILN_2003 GBV_ILN_2004 GBV_ILN_2005 GBV_ILN_2011 GBV_ILN_2014 GBV_ILN_2015 GBV_ILN_2020 GBV_ILN_2021 GBV_ILN_2025 GBV_ILN_2027 GBV_ILN_2034 GBV_ILN_2038 GBV_ILN_2044 GBV_ILN_2048 GBV_ILN_2049 GBV_ILN_2050 GBV_ILN_2056 GBV_ILN_2059 GBV_ILN_2061 GBV_ILN_2064 GBV_ILN_2065 GBV_ILN_2068 GBV_ILN_2111 GBV_ILN_2112 GBV_ILN_2113 GBV_ILN_2118 GBV_ILN_2122 GBV_ILN_2129 GBV_ILN_2143 GBV_ILN_2147 GBV_ILN_2148 GBV_ILN_2152 GBV_ILN_2153 GBV_ILN_2190 GBV_ILN_2336 GBV_ILN_2507 GBV_ILN_2522 GBV_ILN_4035 GBV_ILN_4037 GBV_ILN_4112 GBV_ILN_4125 GBV_ILN_4126 GBV_ILN_4242 GBV_ILN_4251 GBV_ILN_4305 GBV_ILN_4313 GBV_ILN_4323 GBV_ILN_4324 GBV_ILN_4325 GBV_ILN_4326 GBV_ILN_4333 GBV_ILN_4334 GBV_ILN_4335 GBV_ILN_4338 GBV_ILN_4393 44.45 Immunologie AR 39 6585-6590 |
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610 DE-600 44.45 bkl A case series of acute pericarditis following COVID-19 vaccination in the context of recent reports from Europe and the United States COVID-19 vaccination Pericarditis mRNA vaccines Adenovirus vector-based vaccines SARS-CoV-2, outcome |
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A case series of acute pericarditis following COVID-19 vaccination in the context of recent reports from Europe and the United States |
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Lazaros, George Anastassopoulou, Cleo Hatziantoniou, Sophia Kalos, Theodoros Soulaidopoulos, Stergios Lazarou, Emilia Vlachopoulos, Charalambos Vassilopoulos, Dimitrios Tsakris, Athanasios Tsioufis, Costas |
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a case series of acute pericarditis following covid-19 vaccination in the context of recent reports from europe and the united states |
title_auth |
A case series of acute pericarditis following COVID-19 vaccination in the context of recent reports from Europe and the United States |
abstract |
Background: COVID-19 vaccines were efficacious and safe in clinical trials. We report nine events of acute pericarditis (AP) in eight patients following COVID-19 vaccination with BNT162b2 (6/9), AZD1222 (2/9) and mRNA-1273 (1/9).Methods: All patients were referred for AP temporally linked with COVID-19 vaccination. Chest pain was the most common clinical manifestation. Alternative etiologies were excluded upon thorough diagnostic work up. AP diagnosis was established according to ESC guidelines.Findings: Five events occurred after the first vaccine dose and four after the second. The mean age in this cohort was 65.8 ± 10.2 years and the men/women ratio 3/5. All events resolved without sequelae; two events were complicated by cardiac tamponade requiring emergent pericardial decompression. Hospitalization was required in four cases.Interpretation: Although causality cannot be firmly established, AP has emerged as a possible complication following COVID-19 vaccination. Further investigation is indispensable to fully characterize this new entity. |
abstractGer |
Background: COVID-19 vaccines were efficacious and safe in clinical trials. We report nine events of acute pericarditis (AP) in eight patients following COVID-19 vaccination with BNT162b2 (6/9), AZD1222 (2/9) and mRNA-1273 (1/9).Methods: All patients were referred for AP temporally linked with COVID-19 vaccination. Chest pain was the most common clinical manifestation. Alternative etiologies were excluded upon thorough diagnostic work up. AP diagnosis was established according to ESC guidelines.Findings: Five events occurred after the first vaccine dose and four after the second. The mean age in this cohort was 65.8 ± 10.2 years and the men/women ratio 3/5. All events resolved without sequelae; two events were complicated by cardiac tamponade requiring emergent pericardial decompression. Hospitalization was required in four cases.Interpretation: Although causality cannot be firmly established, AP has emerged as a possible complication following COVID-19 vaccination. Further investigation is indispensable to fully characterize this new entity. |
abstract_unstemmed |
Background: COVID-19 vaccines were efficacious and safe in clinical trials. We report nine events of acute pericarditis (AP) in eight patients following COVID-19 vaccination with BNT162b2 (6/9), AZD1222 (2/9) and mRNA-1273 (1/9).Methods: All patients were referred for AP temporally linked with COVID-19 vaccination. Chest pain was the most common clinical manifestation. Alternative etiologies were excluded upon thorough diagnostic work up. AP diagnosis was established according to ESC guidelines.Findings: Five events occurred after the first vaccine dose and four after the second. The mean age in this cohort was 65.8 ± 10.2 years and the men/women ratio 3/5. All events resolved without sequelae; two events were complicated by cardiac tamponade requiring emergent pericardial decompression. Hospitalization was required in four cases.Interpretation: Although causality cannot be firmly established, AP has emerged as a possible complication following COVID-19 vaccination. Further investigation is indispensable to fully characterize this new entity. |
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A case series of acute pericarditis following COVID-19 vaccination in the context of recent reports from Europe and the United States |
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Anastassopoulou, Cleo Hatziantoniou, Sophia Kalos, Theodoros Soulaidopoulos, Stergios Lazarou, Emilia Vlachopoulos, Charalambos Vassilopoulos, Dimitrios Tsakris, Athanasios Tsioufis, Costas |
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