Health Status After Transcatheter Tricuspid Valve Repair in Patients With Functional Tricuspid Regurgitation

Objectives: The aim of this study was to investigate changes in quality of life (QoL) after transcatheter tricuspid valve repair (TTVR) for tricuspid regurgitation (TR).Background: TTVR provides feasible and durable efficacy in reducing TR, but its clinical benefits on QoL still remain unclear.Metho...
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Autor*in:	Kitamura, Mitsunobu [verfasserIn] Kresoja, Karl-Patrik [verfasserIn] Balata, Mahmoud [verfasserIn] Besler, Christian [verfasserIn] Rommel, Karl-Philipp [verfasserIn] Unterhuber, Matthias [verfasserIn] Lurz, Julia [verfasserIn] Rosch, Sebastian [verfasserIn] Gunold, Hilka [verfasserIn] Noack, Thilo [verfasserIn] Thiele, Holger [verfasserIn] Lurz, Philipp [verfasserIn]

Format:	E-Artikel
Sprache:	Englisch

Erschienen:	2021

Schlagwörter:	MLHFQ quality of life SF-36 transcatheter tricuspid valve repair tricuspid regurgitation

Übergeordnetes Werk:	Enthalten in: JACC Cardiovascular interventions - American College of Cardiology ; ID: gnd/1017722-X, New York, NY : Elsevier, 2008, 14
Übergeordnetes Werk:	volume:14

DOI / URN:	10.1016/j.jcin.2021.09.021

Katalog-ID:	ELV007093551

Internformat


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024	7		\|a 10.1016/j.jcin.2021.09.021 \|2 doi
035			\|a (DE-627)ELV007093551
035			\|a (ELSEVIER)S1936-8798(21)01783-0
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100	1		\|a Kitamura, Mitsunobu \|e verfasserin \|4 aut
245	1	0	\|a Health Status After Transcatheter Tricuspid Valve Repair in Patients With Functional Tricuspid Regurgitation
264		1	\|c 2021
336			\|a nicht spezifiziert \|b zzz \|2 rdacontent
337			\|a Computermedien \|b c \|2 rdamedia
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520			\|a Objectives: The aim of this study was to investigate changes in quality of life (QoL) after transcatheter tricuspid valve repair (TTVR) for tricuspid regurgitation (TR).Background: TTVR provides feasible and durable efficacy in reducing TR, but its clinical benefits on QoL still remain unclear.Methods: In 115 subjects undergoing TTVR for severe functional TR, QoL was evaluated using the 36-Item Short Form Health Survey (SF-36) and the Minnesota Living With Heart Failure Questionnaire (MLHFQ). All-cause mortality, heart failure (HF) rehospitalization, and a composite endpoint of all-cause mortality, HF rehospitalization, and repeat TTVR were recorded as clinical events.Results: Successful device implantation was achieved in 110 patients (96%). Moderate or less TR at discharge was achieved in 95 patients (83%). Mean SF-36 physical component summary (PCS) score improved from 34 ± 9 to 37 ± 9 points (+3 points; 95% CI: 1-5 points; P = 0.001), mean SF-36 mental component summary score improved from 49 ± 9 to 51 ± 10 points (+2 points; 95% CI: 0-4 points; P = 0.017), and mean MLHFQ score decreased from 29 ± 14 to 20 ± 15 points (−8 points; 95% CI: −11 to −5 points; P < 0.001). Baseline PCS, moderate or less TR at discharge, and baseline massive or torrential TR were associated with 1-month change in PCS score (P < 0.05). Change in PCS score after 1 month predicted HF rehospitalization after TTVR (adjusted HR: 0.74 [95% CI: 0.60-0.92] per 5-point increase in PCS score; P = 0.008).Conclusions: This study demonstrates that TTVR provides improvement in QoL in patients with relevant TR. TR reduction to a moderate or less grade was associated with improvement of SF-36 and MLHFQ scores. Further, global QoL was associated with clinical outcomes and might serve as a future outcome surrogate following TTVR.
650		4	\|a MLHFQ
650		4	\|a quality of life
650		4	\|a SF-36
650		4	\|a transcatheter tricuspid valve repair
650		4	\|a tricuspid regurgitation
700	1		\|a Kresoja, Karl-Patrik \|e verfasserin \|4 aut
700	1		\|a Balata, Mahmoud \|e verfasserin \|4 aut
700	1		\|a Besler, Christian \|e verfasserin \|4 aut
700	1		\|a Rommel, Karl-Philipp \|e verfasserin \|4 aut
700	1		\|a Unterhuber, Matthias \|e verfasserin \|4 aut
700	1		\|a Lurz, Julia \|e verfasserin \|4 aut
700	1		\|a Rosch, Sebastian \|e verfasserin \|4 aut
700	1		\|a Gunold, Hilka \|e verfasserin \|4 aut
700	1		\|a Noack, Thilo \|e verfasserin \|4 aut
700	1		\|a Thiele, Holger \|e verfasserin \|4 aut
700	1		\|a Lurz, Philipp \|e verfasserin \|4 aut
773	0	8	\|i Enthalten in \|a American College of Cardiology ; ID: gnd/1017722-X \|t JACC Cardiovascular interventions \|d New York, NY : Elsevier, 2008 \|g 14 \|h Online-Ressource \|w (DE-627)578539160 \|w (DE-600)2452163-2 \|w (DE-576)294403027 \|x 1876-7605 \|7 nnns
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912			\|a GBV_ILN_2004
912			\|a GBV_ILN_2011
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936	b	k	\|a 44.85 \|j Kardiologie \|j Angiologie
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Indexfelder

author_variant	m k mk k p k kpk m b mb c b cb k p r kpr m u mu j l jl s r sr h g hg t n tn h t ht p l pl
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publishDate	2021
allfields	10.1016/j.jcin.2021.09.021 doi (DE-627)ELV007093551 (ELSEVIER)S1936-8798(21)01783-0 DE-627 ger DE-627 rda eng 610 DE-600 44.85 bkl Kitamura, Mitsunobu verfasserin aut Health Status After Transcatheter Tricuspid Valve Repair in Patients With Functional Tricuspid Regurgitation 2021 nicht spezifiziert zzz rdacontent Computermedien c rdamedia Online-Ressource cr rdacarrier Objectives: The aim of this study was to investigate changes in quality of life (QoL) after transcatheter tricuspid valve repair (TTVR) for tricuspid regurgitation (TR).Background: TTVR provides feasible and durable efficacy in reducing TR, but its clinical benefits on QoL still remain unclear.Methods: In 115 subjects undergoing TTVR for severe functional TR, QoL was evaluated using the 36-Item Short Form Health Survey (SF-36) and the Minnesota Living With Heart Failure Questionnaire (MLHFQ). All-cause mortality, heart failure (HF) rehospitalization, and a composite endpoint of all-cause mortality, HF rehospitalization, and repeat TTVR were recorded as clinical events.Results: Successful device implantation was achieved in 110 patients (96%). Moderate or less TR at discharge was achieved in 95 patients (83%). Mean SF-36 physical component summary (PCS) score improved from 34 ± 9 to 37 ± 9 points (+3 points; 95% CI: 1-5 points; P = 0.001), mean SF-36 mental component summary score improved from 49 ± 9 to 51 ± 10 points (+2 points; 95% CI: 0-4 points; P = 0.017), and mean MLHFQ score decreased from 29 ± 14 to 20 ± 15 points (−8 points; 95% CI: −11 to −5 points; P < 0.001). Baseline PCS, moderate or less TR at discharge, and baseline massive or torrential TR were associated with 1-month change in PCS score (P < 0.05). Change in PCS score after 1 month predicted HF rehospitalization after TTVR (adjusted HR: 0.74 [95% CI: 0.60-0.92] per 5-point increase in PCS score; P = 0.008).Conclusions: This study demonstrates that TTVR provides improvement in QoL in patients with relevant TR. TR reduction to a moderate or less grade was associated with improvement of SF-36 and MLHFQ scores. Further, global QoL was associated with clinical outcomes and might serve as a future outcome surrogate following TTVR. MLHFQ quality of life SF-36 transcatheter tricuspid valve repair tricuspid regurgitation Kresoja, Karl-Patrik verfasserin aut Balata, Mahmoud verfasserin aut Besler, Christian verfasserin aut Rommel, Karl-Philipp verfasserin aut Unterhuber, Matthias verfasserin aut Lurz, Julia verfasserin aut Rosch, Sebastian verfasserin aut Gunold, Hilka verfasserin aut Noack, Thilo verfasserin aut Thiele, Holger verfasserin aut Lurz, Philipp verfasserin aut Enthalten in American College of Cardiology ; ID: gnd/1017722-X JACC Cardiovascular interventions New York, NY : Elsevier, 2008 14 Online-Ressource (DE-627)578539160 (DE-600)2452163-2 (DE-576)294403027 1876-7605 nnns volume:14 GBV_USEFLAG_U SYSFLAG_U GBV_ELV SSG-OLC-PHA GBV_ILN_20 GBV_ILN_22 GBV_ILN_23 GBV_ILN_24 GBV_ILN_31 GBV_ILN_39 GBV_ILN_40 GBV_ILN_60 GBV_ILN_62 GBV_ILN_63 GBV_ILN_65 GBV_ILN_69 GBV_ILN_73 GBV_ILN_74 GBV_ILN_95 GBV_ILN_105 GBV_ILN_110 GBV_ILN_151 GBV_ILN_161 GBV_ILN_170 GBV_ILN_206 GBV_ILN_213 GBV_ILN_230 GBV_ILN_285 GBV_ILN_293 GBV_ILN_602 GBV_ILN_2004 GBV_ILN_2011 GBV_ILN_2014 GBV_ILN_4012 GBV_ILN_4037 GBV_ILN_4112 GBV_ILN_4125 GBV_ILN_4126 GBV_ILN_4249 GBV_ILN_4305 GBV_ILN_4306 GBV_ILN_4307 GBV_ILN_4313 GBV_ILN_4322 GBV_ILN_4323 GBV_ILN_4324 GBV_ILN_4325 GBV_ILN_4338 GBV_ILN_4367 GBV_ILN_4700 44.85 Kardiologie Angiologie AR 14
spelling	10.1016/j.jcin.2021.09.021 doi (DE-627)ELV007093551 (ELSEVIER)S1936-8798(21)01783-0 DE-627 ger DE-627 rda eng 610 DE-600 44.85 bkl Kitamura, Mitsunobu verfasserin aut Health Status After Transcatheter Tricuspid Valve Repair in Patients With Functional Tricuspid Regurgitation 2021 nicht spezifiziert zzz rdacontent Computermedien c rdamedia Online-Ressource cr rdacarrier Objectives: The aim of this study was to investigate changes in quality of life (QoL) after transcatheter tricuspid valve repair (TTVR) for tricuspid regurgitation (TR).Background: TTVR provides feasible and durable efficacy in reducing TR, but its clinical benefits on QoL still remain unclear.Methods: In 115 subjects undergoing TTVR for severe functional TR, QoL was evaluated using the 36-Item Short Form Health Survey (SF-36) and the Minnesota Living With Heart Failure Questionnaire (MLHFQ). All-cause mortality, heart failure (HF) rehospitalization, and a composite endpoint of all-cause mortality, HF rehospitalization, and repeat TTVR were recorded as clinical events.Results: Successful device implantation was achieved in 110 patients (96%). Moderate or less TR at discharge was achieved in 95 patients (83%). Mean SF-36 physical component summary (PCS) score improved from 34 ± 9 to 37 ± 9 points (+3 points; 95% CI: 1-5 points; P = 0.001), mean SF-36 mental component summary score improved from 49 ± 9 to 51 ± 10 points (+2 points; 95% CI: 0-4 points; P = 0.017), and mean MLHFQ score decreased from 29 ± 14 to 20 ± 15 points (−8 points; 95% CI: −11 to −5 points; P < 0.001). Baseline PCS, moderate or less TR at discharge, and baseline massive or torrential TR were associated with 1-month change in PCS score (P < 0.05). Change in PCS score after 1 month predicted HF rehospitalization after TTVR (adjusted HR: 0.74 [95% CI: 0.60-0.92] per 5-point increase in PCS score; P = 0.008).Conclusions: This study demonstrates that TTVR provides improvement in QoL in patients with relevant TR. TR reduction to a moderate or less grade was associated with improvement of SF-36 and MLHFQ scores. Further, global QoL was associated with clinical outcomes and might serve as a future outcome surrogate following TTVR. MLHFQ quality of life SF-36 transcatheter tricuspid valve repair tricuspid regurgitation Kresoja, Karl-Patrik verfasserin aut Balata, Mahmoud verfasserin aut Besler, Christian verfasserin aut Rommel, Karl-Philipp verfasserin aut Unterhuber, Matthias verfasserin aut Lurz, Julia verfasserin aut Rosch, Sebastian verfasserin aut Gunold, Hilka verfasserin aut Noack, Thilo verfasserin aut Thiele, Holger verfasserin aut Lurz, Philipp verfasserin aut Enthalten in American College of Cardiology ; ID: gnd/1017722-X JACC Cardiovascular interventions New York, NY : Elsevier, 2008 14 Online-Ressource (DE-627)578539160 (DE-600)2452163-2 (DE-576)294403027 1876-7605 nnns volume:14 GBV_USEFLAG_U SYSFLAG_U GBV_ELV SSG-OLC-PHA GBV_ILN_20 GBV_ILN_22 GBV_ILN_23 GBV_ILN_24 GBV_ILN_31 GBV_ILN_39 GBV_ILN_40 GBV_ILN_60 GBV_ILN_62 GBV_ILN_63 GBV_ILN_65 GBV_ILN_69 GBV_ILN_73 GBV_ILN_74 GBV_ILN_95 GBV_ILN_105 GBV_ILN_110 GBV_ILN_151 GBV_ILN_161 GBV_ILN_170 GBV_ILN_206 GBV_ILN_213 GBV_ILN_230 GBV_ILN_285 GBV_ILN_293 GBV_ILN_602 GBV_ILN_2004 GBV_ILN_2011 GBV_ILN_2014 GBV_ILN_4012 GBV_ILN_4037 GBV_ILN_4112 GBV_ILN_4125 GBV_ILN_4126 GBV_ILN_4249 GBV_ILN_4305 GBV_ILN_4306 GBV_ILN_4307 GBV_ILN_4313 GBV_ILN_4322 GBV_ILN_4323 GBV_ILN_4324 GBV_ILN_4325 GBV_ILN_4338 GBV_ILN_4367 GBV_ILN_4700 44.85 Kardiologie Angiologie AR 14
allfields_unstemmed	10.1016/j.jcin.2021.09.021 doi (DE-627)ELV007093551 (ELSEVIER)S1936-8798(21)01783-0 DE-627 ger DE-627 rda eng 610 DE-600 44.85 bkl Kitamura, Mitsunobu verfasserin aut Health Status After Transcatheter Tricuspid Valve Repair in Patients With Functional Tricuspid Regurgitation 2021 nicht spezifiziert zzz rdacontent Computermedien c rdamedia Online-Ressource cr rdacarrier Objectives: The aim of this study was to investigate changes in quality of life (QoL) after transcatheter tricuspid valve repair (TTVR) for tricuspid regurgitation (TR).Background: TTVR provides feasible and durable efficacy in reducing TR, but its clinical benefits on QoL still remain unclear.Methods: In 115 subjects undergoing TTVR for severe functional TR, QoL was evaluated using the 36-Item Short Form Health Survey (SF-36) and the Minnesota Living With Heart Failure Questionnaire (MLHFQ). All-cause mortality, heart failure (HF) rehospitalization, and a composite endpoint of all-cause mortality, HF rehospitalization, and repeat TTVR were recorded as clinical events.Results: Successful device implantation was achieved in 110 patients (96%). Moderate or less TR at discharge was achieved in 95 patients (83%). Mean SF-36 physical component summary (PCS) score improved from 34 ± 9 to 37 ± 9 points (+3 points; 95% CI: 1-5 points; P = 0.001), mean SF-36 mental component summary score improved from 49 ± 9 to 51 ± 10 points (+2 points; 95% CI: 0-4 points; P = 0.017), and mean MLHFQ score decreased from 29 ± 14 to 20 ± 15 points (−8 points; 95% CI: −11 to −5 points; P < 0.001). Baseline PCS, moderate or less TR at discharge, and baseline massive or torrential TR were associated with 1-month change in PCS score (P < 0.05). Change in PCS score after 1 month predicted HF rehospitalization after TTVR (adjusted HR: 0.74 [95% CI: 0.60-0.92] per 5-point increase in PCS score; P = 0.008).Conclusions: This study demonstrates that TTVR provides improvement in QoL in patients with relevant TR. TR reduction to a moderate or less grade was associated with improvement of SF-36 and MLHFQ scores. Further, global QoL was associated with clinical outcomes and might serve as a future outcome surrogate following TTVR. MLHFQ quality of life SF-36 transcatheter tricuspid valve repair tricuspid regurgitation Kresoja, Karl-Patrik verfasserin aut Balata, Mahmoud verfasserin aut Besler, Christian verfasserin aut Rommel, Karl-Philipp verfasserin aut Unterhuber, Matthias verfasserin aut Lurz, Julia verfasserin aut Rosch, Sebastian verfasserin aut Gunold, Hilka verfasserin aut Noack, Thilo verfasserin aut Thiele, Holger verfasserin aut Lurz, Philipp verfasserin aut Enthalten in American College of Cardiology ; ID: gnd/1017722-X JACC Cardiovascular interventions New York, NY : Elsevier, 2008 14 Online-Ressource (DE-627)578539160 (DE-600)2452163-2 (DE-576)294403027 1876-7605 nnns volume:14 GBV_USEFLAG_U SYSFLAG_U GBV_ELV SSG-OLC-PHA GBV_ILN_20 GBV_ILN_22 GBV_ILN_23 GBV_ILN_24 GBV_ILN_31 GBV_ILN_39 GBV_ILN_40 GBV_ILN_60 GBV_ILN_62 GBV_ILN_63 GBV_ILN_65 GBV_ILN_69 GBV_ILN_73 GBV_ILN_74 GBV_ILN_95 GBV_ILN_105 GBV_ILN_110 GBV_ILN_151 GBV_ILN_161 GBV_ILN_170 GBV_ILN_206 GBV_ILN_213 GBV_ILN_230 GBV_ILN_285 GBV_ILN_293 GBV_ILN_602 GBV_ILN_2004 GBV_ILN_2011 GBV_ILN_2014 GBV_ILN_4012 GBV_ILN_4037 GBV_ILN_4112 GBV_ILN_4125 GBV_ILN_4126 GBV_ILN_4249 GBV_ILN_4305 GBV_ILN_4306 GBV_ILN_4307 GBV_ILN_4313 GBV_ILN_4322 GBV_ILN_4323 GBV_ILN_4324 GBV_ILN_4325 GBV_ILN_4338 GBV_ILN_4367 GBV_ILN_4700 44.85 Kardiologie Angiologie AR 14
allfieldsGer	10.1016/j.jcin.2021.09.021 doi (DE-627)ELV007093551 (ELSEVIER)S1936-8798(21)01783-0 DE-627 ger DE-627 rda eng 610 DE-600 44.85 bkl Kitamura, Mitsunobu verfasserin aut Health Status After Transcatheter Tricuspid Valve Repair in Patients With Functional Tricuspid Regurgitation 2021 nicht spezifiziert zzz rdacontent Computermedien c rdamedia Online-Ressource cr rdacarrier Objectives: The aim of this study was to investigate changes in quality of life (QoL) after transcatheter tricuspid valve repair (TTVR) for tricuspid regurgitation (TR).Background: TTVR provides feasible and durable efficacy in reducing TR, but its clinical benefits on QoL still remain unclear.Methods: In 115 subjects undergoing TTVR for severe functional TR, QoL was evaluated using the 36-Item Short Form Health Survey (SF-36) and the Minnesota Living With Heart Failure Questionnaire (MLHFQ). All-cause mortality, heart failure (HF) rehospitalization, and a composite endpoint of all-cause mortality, HF rehospitalization, and repeat TTVR were recorded as clinical events.Results: Successful device implantation was achieved in 110 patients (96%). Moderate or less TR at discharge was achieved in 95 patients (83%). Mean SF-36 physical component summary (PCS) score improved from 34 ± 9 to 37 ± 9 points (+3 points; 95% CI: 1-5 points; P = 0.001), mean SF-36 mental component summary score improved from 49 ± 9 to 51 ± 10 points (+2 points; 95% CI: 0-4 points; P = 0.017), and mean MLHFQ score decreased from 29 ± 14 to 20 ± 15 points (−8 points; 95% CI: −11 to −5 points; P < 0.001). Baseline PCS, moderate or less TR at discharge, and baseline massive or torrential TR were associated with 1-month change in PCS score (P < 0.05). Change in PCS score after 1 month predicted HF rehospitalization after TTVR (adjusted HR: 0.74 [95% CI: 0.60-0.92] per 5-point increase in PCS score; P = 0.008).Conclusions: This study demonstrates that TTVR provides improvement in QoL in patients with relevant TR. TR reduction to a moderate or less grade was associated with improvement of SF-36 and MLHFQ scores. Further, global QoL was associated with clinical outcomes and might serve as a future outcome surrogate following TTVR. MLHFQ quality of life SF-36 transcatheter tricuspid valve repair tricuspid regurgitation Kresoja, Karl-Patrik verfasserin aut Balata, Mahmoud verfasserin aut Besler, Christian verfasserin aut Rommel, Karl-Philipp verfasserin aut Unterhuber, Matthias verfasserin aut Lurz, Julia verfasserin aut Rosch, Sebastian verfasserin aut Gunold, Hilka verfasserin aut Noack, Thilo verfasserin aut Thiele, Holger verfasserin aut Lurz, Philipp verfasserin aut Enthalten in American College of Cardiology ; ID: gnd/1017722-X JACC Cardiovascular interventions New York, NY : Elsevier, 2008 14 Online-Ressource (DE-627)578539160 (DE-600)2452163-2 (DE-576)294403027 1876-7605 nnns volume:14 GBV_USEFLAG_U SYSFLAG_U GBV_ELV SSG-OLC-PHA GBV_ILN_20 GBV_ILN_22 GBV_ILN_23 GBV_ILN_24 GBV_ILN_31 GBV_ILN_39 GBV_ILN_40 GBV_ILN_60 GBV_ILN_62 GBV_ILN_63 GBV_ILN_65 GBV_ILN_69 GBV_ILN_73 GBV_ILN_74 GBV_ILN_95 GBV_ILN_105 GBV_ILN_110 GBV_ILN_151 GBV_ILN_161 GBV_ILN_170 GBV_ILN_206 GBV_ILN_213 GBV_ILN_230 GBV_ILN_285 GBV_ILN_293 GBV_ILN_602 GBV_ILN_2004 GBV_ILN_2011 GBV_ILN_2014 GBV_ILN_4012 GBV_ILN_4037 GBV_ILN_4112 GBV_ILN_4125 GBV_ILN_4126 GBV_ILN_4249 GBV_ILN_4305 GBV_ILN_4306 GBV_ILN_4307 GBV_ILN_4313 GBV_ILN_4322 GBV_ILN_4323 GBV_ILN_4324 GBV_ILN_4325 GBV_ILN_4338 GBV_ILN_4367 GBV_ILN_4700 44.85 Kardiologie Angiologie AR 14
allfieldsSound	10.1016/j.jcin.2021.09.021 doi (DE-627)ELV007093551 (ELSEVIER)S1936-8798(21)01783-0 DE-627 ger DE-627 rda eng 610 DE-600 44.85 bkl Kitamura, Mitsunobu verfasserin aut Health Status After Transcatheter Tricuspid Valve Repair in Patients With Functional Tricuspid Regurgitation 2021 nicht spezifiziert zzz rdacontent Computermedien c rdamedia Online-Ressource cr rdacarrier Objectives: The aim of this study was to investigate changes in quality of life (QoL) after transcatheter tricuspid valve repair (TTVR) for tricuspid regurgitation (TR).Background: TTVR provides feasible and durable efficacy in reducing TR, but its clinical benefits on QoL still remain unclear.Methods: In 115 subjects undergoing TTVR for severe functional TR, QoL was evaluated using the 36-Item Short Form Health Survey (SF-36) and the Minnesota Living With Heart Failure Questionnaire (MLHFQ). All-cause mortality, heart failure (HF) rehospitalization, and a composite endpoint of all-cause mortality, HF rehospitalization, and repeat TTVR were recorded as clinical events.Results: Successful device implantation was achieved in 110 patients (96%). Moderate or less TR at discharge was achieved in 95 patients (83%). Mean SF-36 physical component summary (PCS) score improved from 34 ± 9 to 37 ± 9 points (+3 points; 95% CI: 1-5 points; P = 0.001), mean SF-36 mental component summary score improved from 49 ± 9 to 51 ± 10 points (+2 points; 95% CI: 0-4 points; P = 0.017), and mean MLHFQ score decreased from 29 ± 14 to 20 ± 15 points (−8 points; 95% CI: −11 to −5 points; P < 0.001). Baseline PCS, moderate or less TR at discharge, and baseline massive or torrential TR were associated with 1-month change in PCS score (P < 0.05). Change in PCS score after 1 month predicted HF rehospitalization after TTVR (adjusted HR: 0.74 [95% CI: 0.60-0.92] per 5-point increase in PCS score; P = 0.008).Conclusions: This study demonstrates that TTVR provides improvement in QoL in patients with relevant TR. TR reduction to a moderate or less grade was associated with improvement of SF-36 and MLHFQ scores. Further, global QoL was associated with clinical outcomes and might serve as a future outcome surrogate following TTVR. MLHFQ quality of life SF-36 transcatheter tricuspid valve repair tricuspid regurgitation Kresoja, Karl-Patrik verfasserin aut Balata, Mahmoud verfasserin aut Besler, Christian verfasserin aut Rommel, Karl-Philipp verfasserin aut Unterhuber, Matthias verfasserin aut Lurz, Julia verfasserin aut Rosch, Sebastian verfasserin aut Gunold, Hilka verfasserin aut Noack, Thilo verfasserin aut Thiele, Holger verfasserin aut Lurz, Philipp verfasserin aut Enthalten in American College of Cardiology ; ID: gnd/1017722-X JACC Cardiovascular interventions New York, NY : Elsevier, 2008 14 Online-Ressource (DE-627)578539160 (DE-600)2452163-2 (DE-576)294403027 1876-7605 nnns volume:14 GBV_USEFLAG_U SYSFLAG_U GBV_ELV SSG-OLC-PHA GBV_ILN_20 GBV_ILN_22 GBV_ILN_23 GBV_ILN_24 GBV_ILN_31 GBV_ILN_39 GBV_ILN_40 GBV_ILN_60 GBV_ILN_62 GBV_ILN_63 GBV_ILN_65 GBV_ILN_69 GBV_ILN_73 GBV_ILN_74 GBV_ILN_95 GBV_ILN_105 GBV_ILN_110 GBV_ILN_151 GBV_ILN_161 GBV_ILN_170 GBV_ILN_206 GBV_ILN_213 GBV_ILN_230 GBV_ILN_285 GBV_ILN_293 GBV_ILN_602 GBV_ILN_2004 GBV_ILN_2011 GBV_ILN_2014 GBV_ILN_4012 GBV_ILN_4037 GBV_ILN_4112 GBV_ILN_4125 GBV_ILN_4126 GBV_ILN_4249 GBV_ILN_4305 GBV_ILN_4306 GBV_ILN_4307 GBV_ILN_4313 GBV_ILN_4322 GBV_ILN_4323 GBV_ILN_4324 GBV_ILN_4325 GBV_ILN_4338 GBV_ILN_4367 GBV_ILN_4700 44.85 Kardiologie Angiologie AR 14
language	English
source	Enthalten in JACC Cardiovascular interventions 14 volume:14
sourceStr	Enthalten in JACC Cardiovascular interventions 14 volume:14
format_phy_str_mv	Article
bklname	Kardiologie Angiologie
institution	findex.gbv.de
topic_facet	MLHFQ quality of life SF-36 transcatheter tricuspid valve repair tricuspid regurgitation
dewey-raw	610
isfreeaccess_bool	false
container_title	JACC Cardiovascular interventions
authorswithroles_txt_mv	Kitamura, Mitsunobu @@aut@@ Kresoja, Karl-Patrik @@aut@@ Balata, Mahmoud @@aut@@ Besler, Christian @@aut@@ Rommel, Karl-Philipp @@aut@@ Unterhuber, Matthias @@aut@@ Lurz, Julia @@aut@@ Rosch, Sebastian @@aut@@ Gunold, Hilka @@aut@@ Noack, Thilo @@aut@@ Thiele, Holger @@aut@@ Lurz, Philipp @@aut@@
publishDateDaySort_date	2021-01-01T00:00:00Z
hierarchy_top_id	578539160
dewey-sort	3610
id	ELV007093551
language_de	englisch
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author	Kitamura, Mitsunobu
spellingShingle	Kitamura, Mitsunobu ddc 610 bkl 44.85 misc MLHFQ misc quality of life misc SF-36 misc transcatheter tricuspid valve repair misc tricuspid regurgitation Health Status After Transcatheter Tricuspid Valve Repair in Patients With Functional Tricuspid Regurgitation
authorStr	Kitamura, Mitsunobu
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topic_title	610 DE-600 44.85 bkl Health Status After Transcatheter Tricuspid Valve Repair in Patients With Functional Tricuspid Regurgitation MLHFQ quality of life SF-36 transcatheter tricuspid valve repair tricuspid regurgitation
topic	ddc 610 bkl 44.85 misc MLHFQ misc quality of life misc SF-36 misc transcatheter tricuspid valve repair misc tricuspid regurgitation
topic_unstemmed	ddc 610 bkl 44.85 misc MLHFQ misc quality of life misc SF-36 misc transcatheter tricuspid valve repair misc tricuspid regurgitation
topic_browse	ddc 610 bkl 44.85 misc MLHFQ misc quality of life misc SF-36 misc transcatheter tricuspid valve repair misc tricuspid regurgitation
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title	Health Status After Transcatheter Tricuspid Valve Repair in Patients With Functional Tricuspid Regurgitation
ctrlnum	(DE-627)ELV007093551 (ELSEVIER)S1936-8798(21)01783-0
title_full	Health Status After Transcatheter Tricuspid Valve Repair in Patients With Functional Tricuspid Regurgitation
author_sort	Kitamura, Mitsunobu
journal	JACC Cardiovascular interventions
journalStr	JACC Cardiovascular interventions
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author_browse	Kitamura, Mitsunobu Kresoja, Karl-Patrik Balata, Mahmoud Besler, Christian Rommel, Karl-Philipp Unterhuber, Matthias Lurz, Julia Rosch, Sebastian Gunold, Hilka Noack, Thilo Thiele, Holger Lurz, Philipp
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author-letter	Kitamura, Mitsunobu
doi_str_mv	10.1016/j.jcin.2021.09.021
dewey-full	610
author2-role	verfasserin
title_sort	health status after transcatheter tricuspid valve repair in patients with functional tricuspid regurgitation
title_auth	Health Status After Transcatheter Tricuspid Valve Repair in Patients With Functional Tricuspid Regurgitation
abstract	Objectives: The aim of this study was to investigate changes in quality of life (QoL) after transcatheter tricuspid valve repair (TTVR) for tricuspid regurgitation (TR).Background: TTVR provides feasible and durable efficacy in reducing TR, but its clinical benefits on QoL still remain unclear.Methods: In 115 subjects undergoing TTVR for severe functional TR, QoL was evaluated using the 36-Item Short Form Health Survey (SF-36) and the Minnesota Living With Heart Failure Questionnaire (MLHFQ). All-cause mortality, heart failure (HF) rehospitalization, and a composite endpoint of all-cause mortality, HF rehospitalization, and repeat TTVR were recorded as clinical events.Results: Successful device implantation was achieved in 110 patients (96%). Moderate or less TR at discharge was achieved in 95 patients (83%). Mean SF-36 physical component summary (PCS) score improved from 34 ± 9 to 37 ± 9 points (+3 points; 95% CI: 1-5 points; P = 0.001), mean SF-36 mental component summary score improved from 49 ± 9 to 51 ± 10 points (+2 points; 95% CI: 0-4 points; P = 0.017), and mean MLHFQ score decreased from 29 ± 14 to 20 ± 15 points (−8 points; 95% CI: −11 to −5 points; P < 0.001). Baseline PCS, moderate or less TR at discharge, and baseline massive or torrential TR were associated with 1-month change in PCS score (P < 0.05). Change in PCS score after 1 month predicted HF rehospitalization after TTVR (adjusted HR: 0.74 [95% CI: 0.60-0.92] per 5-point increase in PCS score; P = 0.008).Conclusions: This study demonstrates that TTVR provides improvement in QoL in patients with relevant TR. TR reduction to a moderate or less grade was associated with improvement of SF-36 and MLHFQ scores. Further, global QoL was associated with clinical outcomes and might serve as a future outcome surrogate following TTVR.
abstractGer	Objectives: The aim of this study was to investigate changes in quality of life (QoL) after transcatheter tricuspid valve repair (TTVR) for tricuspid regurgitation (TR).Background: TTVR provides feasible and durable efficacy in reducing TR, but its clinical benefits on QoL still remain unclear.Methods: In 115 subjects undergoing TTVR for severe functional TR, QoL was evaluated using the 36-Item Short Form Health Survey (SF-36) and the Minnesota Living With Heart Failure Questionnaire (MLHFQ). All-cause mortality, heart failure (HF) rehospitalization, and a composite endpoint of all-cause mortality, HF rehospitalization, and repeat TTVR were recorded as clinical events.Results: Successful device implantation was achieved in 110 patients (96%). Moderate or less TR at discharge was achieved in 95 patients (83%). Mean SF-36 physical component summary (PCS) score improved from 34 ± 9 to 37 ± 9 points (+3 points; 95% CI: 1-5 points; P = 0.001), mean SF-36 mental component summary score improved from 49 ± 9 to 51 ± 10 points (+2 points; 95% CI: 0-4 points; P = 0.017), and mean MLHFQ score decreased from 29 ± 14 to 20 ± 15 points (−8 points; 95% CI: −11 to −5 points; P < 0.001). Baseline PCS, moderate or less TR at discharge, and baseline massive or torrential TR were associated with 1-month change in PCS score (P < 0.05). Change in PCS score after 1 month predicted HF rehospitalization after TTVR (adjusted HR: 0.74 [95% CI: 0.60-0.92] per 5-point increase in PCS score; P = 0.008).Conclusions: This study demonstrates that TTVR provides improvement in QoL in patients with relevant TR. TR reduction to a moderate or less grade was associated with improvement of SF-36 and MLHFQ scores. Further, global QoL was associated with clinical outcomes and might serve as a future outcome surrogate following TTVR.
abstract_unstemmed	Objectives: The aim of this study was to investigate changes in quality of life (QoL) after transcatheter tricuspid valve repair (TTVR) for tricuspid regurgitation (TR).Background: TTVR provides feasible and durable efficacy in reducing TR, but its clinical benefits on QoL still remain unclear.Methods: In 115 subjects undergoing TTVR for severe functional TR, QoL was evaluated using the 36-Item Short Form Health Survey (SF-36) and the Minnesota Living With Heart Failure Questionnaire (MLHFQ). All-cause mortality, heart failure (HF) rehospitalization, and a composite endpoint of all-cause mortality, HF rehospitalization, and repeat TTVR were recorded as clinical events.Results: Successful device implantation was achieved in 110 patients (96%). Moderate or less TR at discharge was achieved in 95 patients (83%). Mean SF-36 physical component summary (PCS) score improved from 34 ± 9 to 37 ± 9 points (+3 points; 95% CI: 1-5 points; P = 0.001), mean SF-36 mental component summary score improved from 49 ± 9 to 51 ± 10 points (+2 points; 95% CI: 0-4 points; P = 0.017), and mean MLHFQ score decreased from 29 ± 14 to 20 ± 15 points (−8 points; 95% CI: −11 to −5 points; P < 0.001). Baseline PCS, moderate or less TR at discharge, and baseline massive or torrential TR were associated with 1-month change in PCS score (P < 0.05). Change in PCS score after 1 month predicted HF rehospitalization after TTVR (adjusted HR: 0.74 [95% CI: 0.60-0.92] per 5-point increase in PCS score; P = 0.008).Conclusions: This study demonstrates that TTVR provides improvement in QoL in patients with relevant TR. TR reduction to a moderate or less grade was associated with improvement of SF-36 and MLHFQ scores. Further, global QoL was associated with clinical outcomes and might serve as a future outcome surrogate following TTVR.
collection_details	GBV_USEFLAG_U SYSFLAG_U GBV_ELV SSG-OLC-PHA GBV_ILN_20 GBV_ILN_22 GBV_ILN_23 GBV_ILN_24 GBV_ILN_31 GBV_ILN_39 GBV_ILN_40 GBV_ILN_60 GBV_ILN_62 GBV_ILN_63 GBV_ILN_65 GBV_ILN_69 GBV_ILN_73 GBV_ILN_74 GBV_ILN_95 GBV_ILN_105 GBV_ILN_110 GBV_ILN_151 GBV_ILN_161 GBV_ILN_170 GBV_ILN_206 GBV_ILN_213 GBV_ILN_230 GBV_ILN_285 GBV_ILN_293 GBV_ILN_602 GBV_ILN_2004 GBV_ILN_2011 GBV_ILN_2014 GBV_ILN_4012 GBV_ILN_4037 GBV_ILN_4112 GBV_ILN_4125 GBV_ILN_4126 GBV_ILN_4249 GBV_ILN_4305 GBV_ILN_4306 GBV_ILN_4307 GBV_ILN_4313 GBV_ILN_4322 GBV_ILN_4323 GBV_ILN_4324 GBV_ILN_4325 GBV_ILN_4338 GBV_ILN_4367 GBV_ILN_4700
title_short	Health Status After Transcatheter Tricuspid Valve Repair in Patients With Functional Tricuspid Regurgitation
remote_bool	true
author2	Kresoja, Karl-Patrik Balata, Mahmoud Besler, Christian Rommel, Karl-Philipp Unterhuber, Matthias Lurz, Julia Rosch, Sebastian Gunold, Hilka Noack, Thilo Thiele, Holger Lurz, Philipp
author2Str	Kresoja, Karl-Patrik Balata, Mahmoud Besler, Christian Rommel, Karl-Philipp Unterhuber, Matthias Lurz, Julia Rosch, Sebastian Gunold, Hilka Noack, Thilo Thiele, Holger Lurz, Philipp
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doi_str	10.1016/j.jcin.2021.09.021
up_date	2024-07-06T23:35:41.742Z
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