The pathology of healing and repair
Tissues that have been damaged respond by complex interactions between haemostatic, inflammatory and immunological mechanisms. Understanding these processes is central to promoting good outcomes in clinical practice, whether the injury is due to a disease or to the surgeon's scalpel. Although t...
Ausführliche Beschreibung
Autor*in: |
Carr, Norman J. [verfasserIn] |
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Format: |
E-Artikel |
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Sprache: |
Englisch |
Erschienen: |
2021 |
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Schlagwörter: |
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Übergeordnetes Werk: |
Enthalten in: Surgery - Abingdon : Medicine Publishing Company, 2002, 40, Seite 13-19 |
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Übergeordnetes Werk: |
volume:40 ; pages:13-19 |
DOI / URN: |
10.1016/j.mpsur.2021.11.003 |
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Katalog-ID: |
ELV007222432 |
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520 | |a Tissues that have been damaged respond by complex interactions between haemostatic, inflammatory and immunological mechanisms. Understanding these processes is central to promoting good outcomes in clinical practice, whether the injury is due to a disease or to the surgeon's scalpel. Although there are common themes that apply throughout the body, the details vary according to the type of injury and the tissues involved. This article describes general principles of healing by regeneration and repair, then wound healing in the skin by primary and secondary intention is used to illustrate the stages of haemostasis, inflammation, proliferation and remodelling. Healing mechanisms in the central nervous system and bone are also discussed, as are complications that can result from repair processes. Factors affecting healing and repair are covered with emphasis on principles relevant to surgery. | ||
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10.1016/j.mpsur.2021.11.003 doi (DE-627)ELV007222432 (ELSEVIER)S0263-9319(21)00237-4 DE-627 ger DE-627 rda eng 610 DE-600 44.65 bkl Carr, Norman J. verfasserin aut The pathology of healing and repair 2021 nicht spezifiziert zzz rdacontent Computermedien c rdamedia Online-Ressource cr rdacarrier Tissues that have been damaged respond by complex interactions between haemostatic, inflammatory and immunological mechanisms. Understanding these processes is central to promoting good outcomes in clinical practice, whether the injury is due to a disease or to the surgeon's scalpel. Although there are common themes that apply throughout the body, the details vary according to the type of injury and the tissues involved. This article describes general principles of healing by regeneration and repair, then wound healing in the skin by primary and secondary intention is used to illustrate the stages of haemostasis, inflammation, proliferation and remodelling. Healing mechanisms in the central nervous system and bone are also discussed, as are complications that can result from repair processes. Factors affecting healing and repair are covered with emphasis on principles relevant to surgery. Granulation primary repair repair resolution secondary repair wound healing Enthalten in Surgery Abingdon : Medicine Publishing Company, 2002 40, Seite 13-19 Online-Ressource (DE-627)481905790 (DE-600)2180570-2 (DE-576)272350427 1878-1764 nnns volume:40 pages:13-19 GBV_USEFLAG_U SYSFLAG_U GBV_ELV GBV_ILN_20 GBV_ILN_22 GBV_ILN_23 GBV_ILN_24 GBV_ILN_31 GBV_ILN_32 GBV_ILN_40 GBV_ILN_60 GBV_ILN_62 GBV_ILN_63 GBV_ILN_65 GBV_ILN_69 GBV_ILN_70 GBV_ILN_73 GBV_ILN_74 GBV_ILN_90 GBV_ILN_95 GBV_ILN_100 GBV_ILN_101 GBV_ILN_105 GBV_ILN_110 GBV_ILN_151 GBV_ILN_224 GBV_ILN_370 GBV_ILN_602 GBV_ILN_702 GBV_ILN_2001 GBV_ILN_2003 GBV_ILN_2004 GBV_ILN_2005 GBV_ILN_2006 GBV_ILN_2008 GBV_ILN_2011 GBV_ILN_2014 GBV_ILN_2015 GBV_ILN_2020 GBV_ILN_2021 GBV_ILN_2025 GBV_ILN_2026 GBV_ILN_2027 GBV_ILN_2034 GBV_ILN_2038 GBV_ILN_2044 GBV_ILN_2048 GBV_ILN_2049 GBV_ILN_2050 GBV_ILN_2055 GBV_ILN_2056 GBV_ILN_2059 GBV_ILN_2061 GBV_ILN_2064 GBV_ILN_2065 GBV_ILN_2068 GBV_ILN_2088 GBV_ILN_2111 GBV_ILN_2112 GBV_ILN_2113 GBV_ILN_2118 GBV_ILN_2122 GBV_ILN_2129 GBV_ILN_2143 GBV_ILN_2147 GBV_ILN_2148 GBV_ILN_2152 GBV_ILN_2153 GBV_ILN_2190 GBV_ILN_2232 GBV_ILN_2336 GBV_ILN_2470 GBV_ILN_2507 GBV_ILN_2522 GBV_ILN_4035 GBV_ILN_4037 GBV_ILN_4046 GBV_ILN_4112 GBV_ILN_4125 GBV_ILN_4126 GBV_ILN_4242 GBV_ILN_4251 GBV_ILN_4305 GBV_ILN_4313 GBV_ILN_4322 GBV_ILN_4323 GBV_ILN_4324 GBV_ILN_4325 GBV_ILN_4326 GBV_ILN_4333 GBV_ILN_4334 GBV_ILN_4335 GBV_ILN_4338 GBV_ILN_4393 44.65 Chirurgie AR 40 13-19 |
spelling |
10.1016/j.mpsur.2021.11.003 doi (DE-627)ELV007222432 (ELSEVIER)S0263-9319(21)00237-4 DE-627 ger DE-627 rda eng 610 DE-600 44.65 bkl Carr, Norman J. verfasserin aut The pathology of healing and repair 2021 nicht spezifiziert zzz rdacontent Computermedien c rdamedia Online-Ressource cr rdacarrier Tissues that have been damaged respond by complex interactions between haemostatic, inflammatory and immunological mechanisms. Understanding these processes is central to promoting good outcomes in clinical practice, whether the injury is due to a disease or to the surgeon's scalpel. Although there are common themes that apply throughout the body, the details vary according to the type of injury and the tissues involved. This article describes general principles of healing by regeneration and repair, then wound healing in the skin by primary and secondary intention is used to illustrate the stages of haemostasis, inflammation, proliferation and remodelling. Healing mechanisms in the central nervous system and bone are also discussed, as are complications that can result from repair processes. Factors affecting healing and repair are covered with emphasis on principles relevant to surgery. Granulation primary repair repair resolution secondary repair wound healing Enthalten in Surgery Abingdon : Medicine Publishing Company, 2002 40, Seite 13-19 Online-Ressource (DE-627)481905790 (DE-600)2180570-2 (DE-576)272350427 1878-1764 nnns volume:40 pages:13-19 GBV_USEFLAG_U SYSFLAG_U GBV_ELV GBV_ILN_20 GBV_ILN_22 GBV_ILN_23 GBV_ILN_24 GBV_ILN_31 GBV_ILN_32 GBV_ILN_40 GBV_ILN_60 GBV_ILN_62 GBV_ILN_63 GBV_ILN_65 GBV_ILN_69 GBV_ILN_70 GBV_ILN_73 GBV_ILN_74 GBV_ILN_90 GBV_ILN_95 GBV_ILN_100 GBV_ILN_101 GBV_ILN_105 GBV_ILN_110 GBV_ILN_151 GBV_ILN_224 GBV_ILN_370 GBV_ILN_602 GBV_ILN_702 GBV_ILN_2001 GBV_ILN_2003 GBV_ILN_2004 GBV_ILN_2005 GBV_ILN_2006 GBV_ILN_2008 GBV_ILN_2011 GBV_ILN_2014 GBV_ILN_2015 GBV_ILN_2020 GBV_ILN_2021 GBV_ILN_2025 GBV_ILN_2026 GBV_ILN_2027 GBV_ILN_2034 GBV_ILN_2038 GBV_ILN_2044 GBV_ILN_2048 GBV_ILN_2049 GBV_ILN_2050 GBV_ILN_2055 GBV_ILN_2056 GBV_ILN_2059 GBV_ILN_2061 GBV_ILN_2064 GBV_ILN_2065 GBV_ILN_2068 GBV_ILN_2088 GBV_ILN_2111 GBV_ILN_2112 GBV_ILN_2113 GBV_ILN_2118 GBV_ILN_2122 GBV_ILN_2129 GBV_ILN_2143 GBV_ILN_2147 GBV_ILN_2148 GBV_ILN_2152 GBV_ILN_2153 GBV_ILN_2190 GBV_ILN_2232 GBV_ILN_2336 GBV_ILN_2470 GBV_ILN_2507 GBV_ILN_2522 GBV_ILN_4035 GBV_ILN_4037 GBV_ILN_4046 GBV_ILN_4112 GBV_ILN_4125 GBV_ILN_4126 GBV_ILN_4242 GBV_ILN_4251 GBV_ILN_4305 GBV_ILN_4313 GBV_ILN_4322 GBV_ILN_4323 GBV_ILN_4324 GBV_ILN_4325 GBV_ILN_4326 GBV_ILN_4333 GBV_ILN_4334 GBV_ILN_4335 GBV_ILN_4338 GBV_ILN_4393 44.65 Chirurgie AR 40 13-19 |
allfields_unstemmed |
10.1016/j.mpsur.2021.11.003 doi (DE-627)ELV007222432 (ELSEVIER)S0263-9319(21)00237-4 DE-627 ger DE-627 rda eng 610 DE-600 44.65 bkl Carr, Norman J. verfasserin aut The pathology of healing and repair 2021 nicht spezifiziert zzz rdacontent Computermedien c rdamedia Online-Ressource cr rdacarrier Tissues that have been damaged respond by complex interactions between haemostatic, inflammatory and immunological mechanisms. Understanding these processes is central to promoting good outcomes in clinical practice, whether the injury is due to a disease or to the surgeon's scalpel. Although there are common themes that apply throughout the body, the details vary according to the type of injury and the tissues involved. This article describes general principles of healing by regeneration and repair, then wound healing in the skin by primary and secondary intention is used to illustrate the stages of haemostasis, inflammation, proliferation and remodelling. Healing mechanisms in the central nervous system and bone are also discussed, as are complications that can result from repair processes. Factors affecting healing and repair are covered with emphasis on principles relevant to surgery. Granulation primary repair repair resolution secondary repair wound healing Enthalten in Surgery Abingdon : Medicine Publishing Company, 2002 40, Seite 13-19 Online-Ressource (DE-627)481905790 (DE-600)2180570-2 (DE-576)272350427 1878-1764 nnns volume:40 pages:13-19 GBV_USEFLAG_U SYSFLAG_U GBV_ELV GBV_ILN_20 GBV_ILN_22 GBV_ILN_23 GBV_ILN_24 GBV_ILN_31 GBV_ILN_32 GBV_ILN_40 GBV_ILN_60 GBV_ILN_62 GBV_ILN_63 GBV_ILN_65 GBV_ILN_69 GBV_ILN_70 GBV_ILN_73 GBV_ILN_74 GBV_ILN_90 GBV_ILN_95 GBV_ILN_100 GBV_ILN_101 GBV_ILN_105 GBV_ILN_110 GBV_ILN_151 GBV_ILN_224 GBV_ILN_370 GBV_ILN_602 GBV_ILN_702 GBV_ILN_2001 GBV_ILN_2003 GBV_ILN_2004 GBV_ILN_2005 GBV_ILN_2006 GBV_ILN_2008 GBV_ILN_2011 GBV_ILN_2014 GBV_ILN_2015 GBV_ILN_2020 GBV_ILN_2021 GBV_ILN_2025 GBV_ILN_2026 GBV_ILN_2027 GBV_ILN_2034 GBV_ILN_2038 GBV_ILN_2044 GBV_ILN_2048 GBV_ILN_2049 GBV_ILN_2050 GBV_ILN_2055 GBV_ILN_2056 GBV_ILN_2059 GBV_ILN_2061 GBV_ILN_2064 GBV_ILN_2065 GBV_ILN_2068 GBV_ILN_2088 GBV_ILN_2111 GBV_ILN_2112 GBV_ILN_2113 GBV_ILN_2118 GBV_ILN_2122 GBV_ILN_2129 GBV_ILN_2143 GBV_ILN_2147 GBV_ILN_2148 GBV_ILN_2152 GBV_ILN_2153 GBV_ILN_2190 GBV_ILN_2232 GBV_ILN_2336 GBV_ILN_2470 GBV_ILN_2507 GBV_ILN_2522 GBV_ILN_4035 GBV_ILN_4037 GBV_ILN_4046 GBV_ILN_4112 GBV_ILN_4125 GBV_ILN_4126 GBV_ILN_4242 GBV_ILN_4251 GBV_ILN_4305 GBV_ILN_4313 GBV_ILN_4322 GBV_ILN_4323 GBV_ILN_4324 GBV_ILN_4325 GBV_ILN_4326 GBV_ILN_4333 GBV_ILN_4334 GBV_ILN_4335 GBV_ILN_4338 GBV_ILN_4393 44.65 Chirurgie AR 40 13-19 |
allfieldsGer |
10.1016/j.mpsur.2021.11.003 doi (DE-627)ELV007222432 (ELSEVIER)S0263-9319(21)00237-4 DE-627 ger DE-627 rda eng 610 DE-600 44.65 bkl Carr, Norman J. verfasserin aut The pathology of healing and repair 2021 nicht spezifiziert zzz rdacontent Computermedien c rdamedia Online-Ressource cr rdacarrier Tissues that have been damaged respond by complex interactions between haemostatic, inflammatory and immunological mechanisms. Understanding these processes is central to promoting good outcomes in clinical practice, whether the injury is due to a disease or to the surgeon's scalpel. Although there are common themes that apply throughout the body, the details vary according to the type of injury and the tissues involved. This article describes general principles of healing by regeneration and repair, then wound healing in the skin by primary and secondary intention is used to illustrate the stages of haemostasis, inflammation, proliferation and remodelling. Healing mechanisms in the central nervous system and bone are also discussed, as are complications that can result from repair processes. Factors affecting healing and repair are covered with emphasis on principles relevant to surgery. Granulation primary repair repair resolution secondary repair wound healing Enthalten in Surgery Abingdon : Medicine Publishing Company, 2002 40, Seite 13-19 Online-Ressource (DE-627)481905790 (DE-600)2180570-2 (DE-576)272350427 1878-1764 nnns volume:40 pages:13-19 GBV_USEFLAG_U SYSFLAG_U GBV_ELV GBV_ILN_20 GBV_ILN_22 GBV_ILN_23 GBV_ILN_24 GBV_ILN_31 GBV_ILN_32 GBV_ILN_40 GBV_ILN_60 GBV_ILN_62 GBV_ILN_63 GBV_ILN_65 GBV_ILN_69 GBV_ILN_70 GBV_ILN_73 GBV_ILN_74 GBV_ILN_90 GBV_ILN_95 GBV_ILN_100 GBV_ILN_101 GBV_ILN_105 GBV_ILN_110 GBV_ILN_151 GBV_ILN_224 GBV_ILN_370 GBV_ILN_602 GBV_ILN_702 GBV_ILN_2001 GBV_ILN_2003 GBV_ILN_2004 GBV_ILN_2005 GBV_ILN_2006 GBV_ILN_2008 GBV_ILN_2011 GBV_ILN_2014 GBV_ILN_2015 GBV_ILN_2020 GBV_ILN_2021 GBV_ILN_2025 GBV_ILN_2026 GBV_ILN_2027 GBV_ILN_2034 GBV_ILN_2038 GBV_ILN_2044 GBV_ILN_2048 GBV_ILN_2049 GBV_ILN_2050 GBV_ILN_2055 GBV_ILN_2056 GBV_ILN_2059 GBV_ILN_2061 GBV_ILN_2064 GBV_ILN_2065 GBV_ILN_2068 GBV_ILN_2088 GBV_ILN_2111 GBV_ILN_2112 GBV_ILN_2113 GBV_ILN_2118 GBV_ILN_2122 GBV_ILN_2129 GBV_ILN_2143 GBV_ILN_2147 GBV_ILN_2148 GBV_ILN_2152 GBV_ILN_2153 GBV_ILN_2190 GBV_ILN_2232 GBV_ILN_2336 GBV_ILN_2470 GBV_ILN_2507 GBV_ILN_2522 GBV_ILN_4035 GBV_ILN_4037 GBV_ILN_4046 GBV_ILN_4112 GBV_ILN_4125 GBV_ILN_4126 GBV_ILN_4242 GBV_ILN_4251 GBV_ILN_4305 GBV_ILN_4313 GBV_ILN_4322 GBV_ILN_4323 GBV_ILN_4324 GBV_ILN_4325 GBV_ILN_4326 GBV_ILN_4333 GBV_ILN_4334 GBV_ILN_4335 GBV_ILN_4338 GBV_ILN_4393 44.65 Chirurgie AR 40 13-19 |
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10.1016/j.mpsur.2021.11.003 doi (DE-627)ELV007222432 (ELSEVIER)S0263-9319(21)00237-4 DE-627 ger DE-627 rda eng 610 DE-600 44.65 bkl Carr, Norman J. verfasserin aut The pathology of healing and repair 2021 nicht spezifiziert zzz rdacontent Computermedien c rdamedia Online-Ressource cr rdacarrier Tissues that have been damaged respond by complex interactions between haemostatic, inflammatory and immunological mechanisms. Understanding these processes is central to promoting good outcomes in clinical practice, whether the injury is due to a disease or to the surgeon's scalpel. Although there are common themes that apply throughout the body, the details vary according to the type of injury and the tissues involved. This article describes general principles of healing by regeneration and repair, then wound healing in the skin by primary and secondary intention is used to illustrate the stages of haemostasis, inflammation, proliferation and remodelling. Healing mechanisms in the central nervous system and bone are also discussed, as are complications that can result from repair processes. Factors affecting healing and repair are covered with emphasis on principles relevant to surgery. Granulation primary repair repair resolution secondary repair wound healing Enthalten in Surgery Abingdon : Medicine Publishing Company, 2002 40, Seite 13-19 Online-Ressource (DE-627)481905790 (DE-600)2180570-2 (DE-576)272350427 1878-1764 nnns volume:40 pages:13-19 GBV_USEFLAG_U SYSFLAG_U GBV_ELV GBV_ILN_20 GBV_ILN_22 GBV_ILN_23 GBV_ILN_24 GBV_ILN_31 GBV_ILN_32 GBV_ILN_40 GBV_ILN_60 GBV_ILN_62 GBV_ILN_63 GBV_ILN_65 GBV_ILN_69 GBV_ILN_70 GBV_ILN_73 GBV_ILN_74 GBV_ILN_90 GBV_ILN_95 GBV_ILN_100 GBV_ILN_101 GBV_ILN_105 GBV_ILN_110 GBV_ILN_151 GBV_ILN_224 GBV_ILN_370 GBV_ILN_602 GBV_ILN_702 GBV_ILN_2001 GBV_ILN_2003 GBV_ILN_2004 GBV_ILN_2005 GBV_ILN_2006 GBV_ILN_2008 GBV_ILN_2011 GBV_ILN_2014 GBV_ILN_2015 GBV_ILN_2020 GBV_ILN_2021 GBV_ILN_2025 GBV_ILN_2026 GBV_ILN_2027 GBV_ILN_2034 GBV_ILN_2038 GBV_ILN_2044 GBV_ILN_2048 GBV_ILN_2049 GBV_ILN_2050 GBV_ILN_2055 GBV_ILN_2056 GBV_ILN_2059 GBV_ILN_2061 GBV_ILN_2064 GBV_ILN_2065 GBV_ILN_2068 GBV_ILN_2088 GBV_ILN_2111 GBV_ILN_2112 GBV_ILN_2113 GBV_ILN_2118 GBV_ILN_2122 GBV_ILN_2129 GBV_ILN_2143 GBV_ILN_2147 GBV_ILN_2148 GBV_ILN_2152 GBV_ILN_2153 GBV_ILN_2190 GBV_ILN_2232 GBV_ILN_2336 GBV_ILN_2470 GBV_ILN_2507 GBV_ILN_2522 GBV_ILN_4035 GBV_ILN_4037 GBV_ILN_4046 GBV_ILN_4112 GBV_ILN_4125 GBV_ILN_4126 GBV_ILN_4242 GBV_ILN_4251 GBV_ILN_4305 GBV_ILN_4313 GBV_ILN_4322 GBV_ILN_4323 GBV_ILN_4324 GBV_ILN_4325 GBV_ILN_4326 GBV_ILN_4333 GBV_ILN_4334 GBV_ILN_4335 GBV_ILN_4338 GBV_ILN_4393 44.65 Chirurgie AR 40 13-19 |
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Tissues that have been damaged respond by complex interactions between haemostatic, inflammatory and immunological mechanisms. Understanding these processes is central to promoting good outcomes in clinical practice, whether the injury is due to a disease or to the surgeon's scalpel. Although there are common themes that apply throughout the body, the details vary according to the type of injury and the tissues involved. This article describes general principles of healing by regeneration and repair, then wound healing in the skin by primary and secondary intention is used to illustrate the stages of haemostasis, inflammation, proliferation and remodelling. Healing mechanisms in the central nervous system and bone are also discussed, as are complications that can result from repair processes. Factors affecting healing and repair are covered with emphasis on principles relevant to surgery. |
abstractGer |
Tissues that have been damaged respond by complex interactions between haemostatic, inflammatory and immunological mechanisms. Understanding these processes is central to promoting good outcomes in clinical practice, whether the injury is due to a disease or to the surgeon's scalpel. Although there are common themes that apply throughout the body, the details vary according to the type of injury and the tissues involved. This article describes general principles of healing by regeneration and repair, then wound healing in the skin by primary and secondary intention is used to illustrate the stages of haemostasis, inflammation, proliferation and remodelling. Healing mechanisms in the central nervous system and bone are also discussed, as are complications that can result from repair processes. Factors affecting healing and repair are covered with emphasis on principles relevant to surgery. |
abstract_unstemmed |
Tissues that have been damaged respond by complex interactions between haemostatic, inflammatory and immunological mechanisms. Understanding these processes is central to promoting good outcomes in clinical practice, whether the injury is due to a disease or to the surgeon's scalpel. Although there are common themes that apply throughout the body, the details vary according to the type of injury and the tissues involved. This article describes general principles of healing by regeneration and repair, then wound healing in the skin by primary and secondary intention is used to illustrate the stages of haemostasis, inflammation, proliferation and remodelling. Healing mechanisms in the central nervous system and bone are also discussed, as are complications that can result from repair processes. Factors affecting healing and repair are covered with emphasis on principles relevant to surgery. |
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<?xml version="1.0" encoding="UTF-8"?><collection xmlns="http://www.loc.gov/MARC21/slim"><record><leader>01000caa a22002652 4500</leader><controlfield tag="001">ELV007222432</controlfield><controlfield tag="003">DE-627</controlfield><controlfield tag="005">20230524143513.0</controlfield><controlfield tag="007">cr uuu---uuuuu</controlfield><controlfield tag="008">230506s2021 xx |||||o 00| ||eng c</controlfield><datafield tag="024" ind1="7" ind2=" "><subfield code="a">10.1016/j.mpsur.2021.11.003</subfield><subfield code="2">doi</subfield></datafield><datafield tag="035" ind1=" " ind2=" "><subfield code="a">(DE-627)ELV007222432</subfield></datafield><datafield tag="035" ind1=" " ind2=" "><subfield code="a">(ELSEVIER)S0263-9319(21)00237-4</subfield></datafield><datafield tag="040" ind1=" " ind2=" "><subfield code="a">DE-627</subfield><subfield code="b">ger</subfield><subfield code="c">DE-627</subfield><subfield code="e">rda</subfield></datafield><datafield tag="041" ind1=" " ind2=" "><subfield code="a">eng</subfield></datafield><datafield tag="082" ind1="0" ind2="4"><subfield code="a">610</subfield><subfield code="q">DE-600</subfield></datafield><datafield tag="084" ind1=" " ind2=" "><subfield code="a">44.65</subfield><subfield code="2">bkl</subfield></datafield><datafield tag="100" ind1="1" ind2=" "><subfield code="a">Carr, Norman J.</subfield><subfield code="e">verfasserin</subfield><subfield code="4">aut</subfield></datafield><datafield tag="245" ind1="1" ind2="0"><subfield code="a">The pathology of healing and repair</subfield></datafield><datafield tag="264" ind1=" " ind2="1"><subfield code="c">2021</subfield></datafield><datafield tag="336" ind1=" " ind2=" "><subfield code="a">nicht spezifiziert</subfield><subfield code="b">zzz</subfield><subfield code="2">rdacontent</subfield></datafield><datafield tag="337" ind1=" " ind2=" "><subfield code="a">Computermedien</subfield><subfield code="b">c</subfield><subfield code="2">rdamedia</subfield></datafield><datafield tag="338" ind1=" " ind2=" "><subfield code="a">Online-Ressource</subfield><subfield code="b">cr</subfield><subfield code="2">rdacarrier</subfield></datafield><datafield tag="520" ind1=" " ind2=" "><subfield code="a">Tissues that have been damaged respond by complex interactions between haemostatic, inflammatory and immunological mechanisms. 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