Association of IL-17A gene polymorphism rs2275913 with the polycystic ovary syndrome in Yunnan Province, China
Objective: Polycystic ovary syndrome (PCOS) is a reproductive system disease with high incidence in women of childbearing age. However, the cause and risk factor are not clear. Our study aims to explore whether IL-17A gene polymorphism rs2275913 is associated with the PCOS in women from Yunnan provi...
Ausführliche Beschreibung
Gespeichert in:
| Autor*in: |
Zou, Li [verfasserIn] Cheng, Yun [verfasserIn] Yang, Linna [verfasserIn] Zhang, Fen [verfasserIn] Zhao, Han [verfasserIn] Nian, Lei [verfasserIn] Li, Yulan [verfasserIn] Feng, Yun [verfasserIn] |
|---|
| Format: |
E-Artikel |
|---|---|
| Sprache: |
Englisch |
| Erschienen: |
2022 |
|---|
| Schlagwörter: |
|---|
| Übergeordnetes Werk: |
Enthalten in: European journal of obstetrics & gynecology and reproductive biology - Amsterdam [u.a.] : Elsevier Science, 1971, 271, Seite 27-30 |
|---|---|
| Übergeordnetes Werk: |
volume:271 ; pages:27-30 |
| DOI / URN: |
10.1016/j.ejogrb.2022.01.031 |
|---|
| Katalog-ID: |
ELV007601050 |
|---|
| LEADER | 01000caa a22002652 4500 | ||
|---|---|---|---|
| 001 | ELV007601050 | ||
| 003 | DE-627 | ||
| 005 | 20240119093053.0 | ||
| 007 | cr uuu---uuuuu | ||
| 008 | 230507s2022 xx |||||o 00| ||eng c | ||
| 024 | 7 | |a 10.1016/j.ejogrb.2022.01.031 |2 doi | |
| 035 | |a (DE-627)ELV007601050 | ||
| 035 | |a (ELSEVIER)S0301-2115(22)00040-9 | ||
| 040 | |a DE-627 |b ger |c DE-627 |e rda | ||
| 041 | |a eng | ||
| 082 | 0 | 4 | |a 610 |q VZ |
| 084 | |a 44.92 |2 bkl | ||
| 100 | 1 | |a Zou, Li |e verfasserin |4 aut | |
| 245 | 1 | 0 | |a Association of IL-17A gene polymorphism rs2275913 with the polycystic ovary syndrome in Yunnan Province, China |
| 264 | 1 | |c 2022 | |
| 336 | |a nicht spezifiziert |b zzz |2 rdacontent | ||
| 337 | |a Computermedien |b c |2 rdamedia | ||
| 338 | |a Online-Ressource |b cr |2 rdacarrier | ||
| 520 | |a Objective: Polycystic ovary syndrome (PCOS) is a reproductive system disease with high incidence in women of childbearing age. However, the cause and risk factor are not clear. Our study aims to explore whether IL-17A gene polymorphism rs2275913 is associated with the PCOS in women from Yunnan province, China.Materials and methods: From January 2018 to December 2020, we collected 287 specimens from PCOS patients and 279 specimens from healthy women. The rs2275913 in the IL-17A promoter region were detected by PCR-Sanger sequencing. Detailed clinical symptoms were recorded and hormone levels were measured on all enrolled individuals. The risk of rs2275913 to PCOS was evaluated by using a multivariate logistic regression model.Results: The distribution of rs2275913 in the control group and the PCOS group was statistically different. The multivariate logistic regression model showed that rs2275913 could increase the risk of PCOS occurrence. Among PCOS patients, patients carrying rs2275913 A allele increased serum IL-17A levels and could lead to more disturbed hormone levels and have a bit severe clinical manifestation.Conclusion: This case-control study proves that the rs2275913 is a risk factor for the occurrence of PCOS. | ||
| 650 | 4 | |a rs2275913 | |
| 650 | 4 | |a Polycystic ovary syndrome | |
| 650 | 4 | |a IL-17A | |
| 650 | 4 | |a Gene polymorphism | |
| 650 | 4 | |a Risk | |
| 700 | 1 | |a Cheng, Yun |e verfasserin |4 aut | |
| 700 | 1 | |a Yang, Linna |e verfasserin |4 aut | |
| 700 | 1 | |a Zhang, Fen |e verfasserin |4 aut | |
| 700 | 1 | |a Zhao, Han |e verfasserin |4 aut | |
| 700 | 1 | |a Nian, Lei |e verfasserin |4 aut | |
| 700 | 1 | |a Li, Yulan |e verfasserin |4 aut | |
| 700 | 1 | |a Feng, Yun |e verfasserin |4 aut | |
| 773 | 0 | 8 | |i Enthalten in |t European journal of obstetrics & gynecology and reproductive biology |d Amsterdam [u.a.] : Elsevier Science, 1971 |g 271, Seite 27-30 |h Online-Ressource |w (DE-627)320443469 |w (DE-600)2005196-7 |w (DE-576)094142106 |x 1872-7654 |7 nnns |
| 773 | 1 | 8 | |g volume:271 |g pages:27-30 |
| 912 | |a GBV_USEFLAG_U | ||
| 912 | |a GBV_ELV | ||
| 912 | |a SYSFLAG_U | ||
| 912 | |a SSG-OLC-PHA | ||
| 912 | |a GBV_ILN_20 | ||
| 912 | |a GBV_ILN_22 | ||
| 912 | |a GBV_ILN_23 | ||
| 912 | |a GBV_ILN_24 | ||
| 912 | |a GBV_ILN_31 | ||
| 912 | |a GBV_ILN_32 | ||
| 912 | |a GBV_ILN_40 | ||
| 912 | |a GBV_ILN_60 | ||
| 912 | |a GBV_ILN_62 | ||
| 912 | |a GBV_ILN_63 | ||
| 912 | |a GBV_ILN_65 | ||
| 912 | |a GBV_ILN_69 | ||
| 912 | |a GBV_ILN_70 | ||
| 912 | |a GBV_ILN_73 | ||
| 912 | |a GBV_ILN_74 | ||
| 912 | |a GBV_ILN_90 | ||
| 912 | |a GBV_ILN_95 | ||
| 912 | |a GBV_ILN_100 | ||
| 912 | |a GBV_ILN_101 | ||
| 912 | |a GBV_ILN_105 | ||
| 912 | |a GBV_ILN_110 | ||
| 912 | |a GBV_ILN_151 | ||
| 912 | |a GBV_ILN_224 | ||
| 912 | |a GBV_ILN_370 | ||
| 912 | |a GBV_ILN_602 | ||
| 912 | |a GBV_ILN_702 | ||
| 912 | |a GBV_ILN_2003 | ||
| 912 | |a GBV_ILN_2004 | ||
| 912 | |a GBV_ILN_2005 | ||
| 912 | |a GBV_ILN_2011 | ||
| 912 | |a GBV_ILN_2014 | ||
| 912 | |a GBV_ILN_2015 | ||
| 912 | |a GBV_ILN_2020 | ||
| 912 | |a GBV_ILN_2021 | ||
| 912 | |a GBV_ILN_2025 | ||
| 912 | |a GBV_ILN_2027 | ||
| 912 | |a GBV_ILN_2034 | ||
| 912 | |a GBV_ILN_2038 | ||
| 912 | |a GBV_ILN_2044 | ||
| 912 | |a GBV_ILN_2048 | ||
| 912 | |a GBV_ILN_2049 | ||
| 912 | |a GBV_ILN_2050 | ||
| 912 | |a GBV_ILN_2056 | ||
| 912 | |a GBV_ILN_2059 | ||
| 912 | |a GBV_ILN_2061 | ||
| 912 | |a GBV_ILN_2064 | ||
| 912 | |a GBV_ILN_2065 | ||
| 912 | |a GBV_ILN_2068 | ||
| 912 | |a GBV_ILN_2111 | ||
| 912 | |a GBV_ILN_2112 | ||
| 912 | |a GBV_ILN_2113 | ||
| 912 | |a GBV_ILN_2118 | ||
| 912 | |a GBV_ILN_2122 | ||
| 912 | |a GBV_ILN_2129 | ||
| 912 | |a GBV_ILN_2143 | ||
| 912 | |a GBV_ILN_2147 | ||
| 912 | |a GBV_ILN_2148 | ||
| 912 | |a GBV_ILN_2152 | ||
| 912 | |a GBV_ILN_2153 | ||
| 912 | |a GBV_ILN_2190 | ||
| 912 | |a GBV_ILN_2336 | ||
| 912 | |a GBV_ILN_2507 | ||
| 912 | |a GBV_ILN_2522 | ||
| 912 | |a GBV_ILN_4035 | ||
| 912 | |a GBV_ILN_4037 | ||
| 912 | |a GBV_ILN_4112 | ||
| 912 | |a GBV_ILN_4125 | ||
| 912 | |a GBV_ILN_4126 | ||
| 912 | |a GBV_ILN_4242 | ||
| 912 | |a GBV_ILN_4251 | ||
| 912 | |a GBV_ILN_4305 | ||
| 912 | |a GBV_ILN_4313 | ||
| 912 | |a GBV_ILN_4323 | ||
| 912 | |a GBV_ILN_4324 | ||
| 912 | |a GBV_ILN_4325 | ||
| 912 | |a GBV_ILN_4326 | ||
| 912 | |a GBV_ILN_4333 | ||
| 912 | |a GBV_ILN_4334 | ||
| 912 | |a GBV_ILN_4335 | ||
| 912 | |a GBV_ILN_4338 | ||
| 912 | |a GBV_ILN_4393 | ||
| 936 | b | k | |a 44.92 |j Gynäkologie |q VZ |
| 951 | |a AR | ||
| 952 | |d 271 |h 27-30 | ||
| author_variant |
l z lz y c yc l y ly f z fz h z hz l n ln y l yl y f yf |
|---|---|
| matchkey_str |
article:18727654:2022----::soitooi1aeeoyopims251wtteoyytcvrsn |
| hierarchy_sort_str |
2022 |
| bklnumber |
44.92 |
| publishDate |
2022 |
| allfields |
10.1016/j.ejogrb.2022.01.031 doi (DE-627)ELV007601050 (ELSEVIER)S0301-2115(22)00040-9 DE-627 ger DE-627 rda eng 610 VZ 44.92 bkl Zou, Li verfasserin aut Association of IL-17A gene polymorphism rs2275913 with the polycystic ovary syndrome in Yunnan Province, China 2022 nicht spezifiziert zzz rdacontent Computermedien c rdamedia Online-Ressource cr rdacarrier Objective: Polycystic ovary syndrome (PCOS) is a reproductive system disease with high incidence in women of childbearing age. However, the cause and risk factor are not clear. Our study aims to explore whether IL-17A gene polymorphism rs2275913 is associated with the PCOS in women from Yunnan province, China.Materials and methods: From January 2018 to December 2020, we collected 287 specimens from PCOS patients and 279 specimens from healthy women. The rs2275913 in the IL-17A promoter region were detected by PCR-Sanger sequencing. Detailed clinical symptoms were recorded and hormone levels were measured on all enrolled individuals. The risk of rs2275913 to PCOS was evaluated by using a multivariate logistic regression model.Results: The distribution of rs2275913 in the control group and the PCOS group was statistically different. The multivariate logistic regression model showed that rs2275913 could increase the risk of PCOS occurrence. Among PCOS patients, patients carrying rs2275913 A allele increased serum IL-17A levels and could lead to more disturbed hormone levels and have a bit severe clinical manifestation.Conclusion: This case-control study proves that the rs2275913 is a risk factor for the occurrence of PCOS. rs2275913 Polycystic ovary syndrome IL-17A Gene polymorphism Risk Cheng, Yun verfasserin aut Yang, Linna verfasserin aut Zhang, Fen verfasserin aut Zhao, Han verfasserin aut Nian, Lei verfasserin aut Li, Yulan verfasserin aut Feng, Yun verfasserin aut Enthalten in European journal of obstetrics & gynecology and reproductive biology Amsterdam [u.a.] : Elsevier Science, 1971 271, Seite 27-30 Online-Ressource (DE-627)320443469 (DE-600)2005196-7 (DE-576)094142106 1872-7654 nnns volume:271 pages:27-30 GBV_USEFLAG_U GBV_ELV SYSFLAG_U SSG-OLC-PHA GBV_ILN_20 GBV_ILN_22 GBV_ILN_23 GBV_ILN_24 GBV_ILN_31 GBV_ILN_32 GBV_ILN_40 GBV_ILN_60 GBV_ILN_62 GBV_ILN_63 GBV_ILN_65 GBV_ILN_69 GBV_ILN_70 GBV_ILN_73 GBV_ILN_74 GBV_ILN_90 GBV_ILN_95 GBV_ILN_100 GBV_ILN_101 GBV_ILN_105 GBV_ILN_110 GBV_ILN_151 GBV_ILN_224 GBV_ILN_370 GBV_ILN_602 GBV_ILN_702 GBV_ILN_2003 GBV_ILN_2004 GBV_ILN_2005 GBV_ILN_2011 GBV_ILN_2014 GBV_ILN_2015 GBV_ILN_2020 GBV_ILN_2021 GBV_ILN_2025 GBV_ILN_2027 GBV_ILN_2034 GBV_ILN_2038 GBV_ILN_2044 GBV_ILN_2048 GBV_ILN_2049 GBV_ILN_2050 GBV_ILN_2056 GBV_ILN_2059 GBV_ILN_2061 GBV_ILN_2064 GBV_ILN_2065 GBV_ILN_2068 GBV_ILN_2111 GBV_ILN_2112 GBV_ILN_2113 GBV_ILN_2118 GBV_ILN_2122 GBV_ILN_2129 GBV_ILN_2143 GBV_ILN_2147 GBV_ILN_2148 GBV_ILN_2152 GBV_ILN_2153 GBV_ILN_2190 GBV_ILN_2336 GBV_ILN_2507 GBV_ILN_2522 GBV_ILN_4035 GBV_ILN_4037 GBV_ILN_4112 GBV_ILN_4125 GBV_ILN_4126 GBV_ILN_4242 GBV_ILN_4251 GBV_ILN_4305 GBV_ILN_4313 GBV_ILN_4323 GBV_ILN_4324 GBV_ILN_4325 GBV_ILN_4326 GBV_ILN_4333 GBV_ILN_4334 GBV_ILN_4335 GBV_ILN_4338 GBV_ILN_4393 44.92 Gynäkologie VZ AR 271 27-30 |
| spelling |
10.1016/j.ejogrb.2022.01.031 doi (DE-627)ELV007601050 (ELSEVIER)S0301-2115(22)00040-9 DE-627 ger DE-627 rda eng 610 VZ 44.92 bkl Zou, Li verfasserin aut Association of IL-17A gene polymorphism rs2275913 with the polycystic ovary syndrome in Yunnan Province, China 2022 nicht spezifiziert zzz rdacontent Computermedien c rdamedia Online-Ressource cr rdacarrier Objective: Polycystic ovary syndrome (PCOS) is a reproductive system disease with high incidence in women of childbearing age. However, the cause and risk factor are not clear. Our study aims to explore whether IL-17A gene polymorphism rs2275913 is associated with the PCOS in women from Yunnan province, China.Materials and methods: From January 2018 to December 2020, we collected 287 specimens from PCOS patients and 279 specimens from healthy women. The rs2275913 in the IL-17A promoter region were detected by PCR-Sanger sequencing. Detailed clinical symptoms were recorded and hormone levels were measured on all enrolled individuals. The risk of rs2275913 to PCOS was evaluated by using a multivariate logistic regression model.Results: The distribution of rs2275913 in the control group and the PCOS group was statistically different. The multivariate logistic regression model showed that rs2275913 could increase the risk of PCOS occurrence. Among PCOS patients, patients carrying rs2275913 A allele increased serum IL-17A levels and could lead to more disturbed hormone levels and have a bit severe clinical manifestation.Conclusion: This case-control study proves that the rs2275913 is a risk factor for the occurrence of PCOS. rs2275913 Polycystic ovary syndrome IL-17A Gene polymorphism Risk Cheng, Yun verfasserin aut Yang, Linna verfasserin aut Zhang, Fen verfasserin aut Zhao, Han verfasserin aut Nian, Lei verfasserin aut Li, Yulan verfasserin aut Feng, Yun verfasserin aut Enthalten in European journal of obstetrics & gynecology and reproductive biology Amsterdam [u.a.] : Elsevier Science, 1971 271, Seite 27-30 Online-Ressource (DE-627)320443469 (DE-600)2005196-7 (DE-576)094142106 1872-7654 nnns volume:271 pages:27-30 GBV_USEFLAG_U GBV_ELV SYSFLAG_U SSG-OLC-PHA GBV_ILN_20 GBV_ILN_22 GBV_ILN_23 GBV_ILN_24 GBV_ILN_31 GBV_ILN_32 GBV_ILN_40 GBV_ILN_60 GBV_ILN_62 GBV_ILN_63 GBV_ILN_65 GBV_ILN_69 GBV_ILN_70 GBV_ILN_73 GBV_ILN_74 GBV_ILN_90 GBV_ILN_95 GBV_ILN_100 GBV_ILN_101 GBV_ILN_105 GBV_ILN_110 GBV_ILN_151 GBV_ILN_224 GBV_ILN_370 GBV_ILN_602 GBV_ILN_702 GBV_ILN_2003 GBV_ILN_2004 GBV_ILN_2005 GBV_ILN_2011 GBV_ILN_2014 GBV_ILN_2015 GBV_ILN_2020 GBV_ILN_2021 GBV_ILN_2025 GBV_ILN_2027 GBV_ILN_2034 GBV_ILN_2038 GBV_ILN_2044 GBV_ILN_2048 GBV_ILN_2049 GBV_ILN_2050 GBV_ILN_2056 GBV_ILN_2059 GBV_ILN_2061 GBV_ILN_2064 GBV_ILN_2065 GBV_ILN_2068 GBV_ILN_2111 GBV_ILN_2112 GBV_ILN_2113 GBV_ILN_2118 GBV_ILN_2122 GBV_ILN_2129 GBV_ILN_2143 GBV_ILN_2147 GBV_ILN_2148 GBV_ILN_2152 GBV_ILN_2153 GBV_ILN_2190 GBV_ILN_2336 GBV_ILN_2507 GBV_ILN_2522 GBV_ILN_4035 GBV_ILN_4037 GBV_ILN_4112 GBV_ILN_4125 GBV_ILN_4126 GBV_ILN_4242 GBV_ILN_4251 GBV_ILN_4305 GBV_ILN_4313 GBV_ILN_4323 GBV_ILN_4324 GBV_ILN_4325 GBV_ILN_4326 GBV_ILN_4333 GBV_ILN_4334 GBV_ILN_4335 GBV_ILN_4338 GBV_ILN_4393 44.92 Gynäkologie VZ AR 271 27-30 |
| allfields_unstemmed |
10.1016/j.ejogrb.2022.01.031 doi (DE-627)ELV007601050 (ELSEVIER)S0301-2115(22)00040-9 DE-627 ger DE-627 rda eng 610 VZ 44.92 bkl Zou, Li verfasserin aut Association of IL-17A gene polymorphism rs2275913 with the polycystic ovary syndrome in Yunnan Province, China 2022 nicht spezifiziert zzz rdacontent Computermedien c rdamedia Online-Ressource cr rdacarrier Objective: Polycystic ovary syndrome (PCOS) is a reproductive system disease with high incidence in women of childbearing age. However, the cause and risk factor are not clear. Our study aims to explore whether IL-17A gene polymorphism rs2275913 is associated with the PCOS in women from Yunnan province, China.Materials and methods: From January 2018 to December 2020, we collected 287 specimens from PCOS patients and 279 specimens from healthy women. The rs2275913 in the IL-17A promoter region were detected by PCR-Sanger sequencing. Detailed clinical symptoms were recorded and hormone levels were measured on all enrolled individuals. The risk of rs2275913 to PCOS was evaluated by using a multivariate logistic regression model.Results: The distribution of rs2275913 in the control group and the PCOS group was statistically different. The multivariate logistic regression model showed that rs2275913 could increase the risk of PCOS occurrence. Among PCOS patients, patients carrying rs2275913 A allele increased serum IL-17A levels and could lead to more disturbed hormone levels and have a bit severe clinical manifestation.Conclusion: This case-control study proves that the rs2275913 is a risk factor for the occurrence of PCOS. rs2275913 Polycystic ovary syndrome IL-17A Gene polymorphism Risk Cheng, Yun verfasserin aut Yang, Linna verfasserin aut Zhang, Fen verfasserin aut Zhao, Han verfasserin aut Nian, Lei verfasserin aut Li, Yulan verfasserin aut Feng, Yun verfasserin aut Enthalten in European journal of obstetrics & gynecology and reproductive biology Amsterdam [u.a.] : Elsevier Science, 1971 271, Seite 27-30 Online-Ressource (DE-627)320443469 (DE-600)2005196-7 (DE-576)094142106 1872-7654 nnns volume:271 pages:27-30 GBV_USEFLAG_U GBV_ELV SYSFLAG_U SSG-OLC-PHA GBV_ILN_20 GBV_ILN_22 GBV_ILN_23 GBV_ILN_24 GBV_ILN_31 GBV_ILN_32 GBV_ILN_40 GBV_ILN_60 GBV_ILN_62 GBV_ILN_63 GBV_ILN_65 GBV_ILN_69 GBV_ILN_70 GBV_ILN_73 GBV_ILN_74 GBV_ILN_90 GBV_ILN_95 GBV_ILN_100 GBV_ILN_101 GBV_ILN_105 GBV_ILN_110 GBV_ILN_151 GBV_ILN_224 GBV_ILN_370 GBV_ILN_602 GBV_ILN_702 GBV_ILN_2003 GBV_ILN_2004 GBV_ILN_2005 GBV_ILN_2011 GBV_ILN_2014 GBV_ILN_2015 GBV_ILN_2020 GBV_ILN_2021 GBV_ILN_2025 GBV_ILN_2027 GBV_ILN_2034 GBV_ILN_2038 GBV_ILN_2044 GBV_ILN_2048 GBV_ILN_2049 GBV_ILN_2050 GBV_ILN_2056 GBV_ILN_2059 GBV_ILN_2061 GBV_ILN_2064 GBV_ILN_2065 GBV_ILN_2068 GBV_ILN_2111 GBV_ILN_2112 GBV_ILN_2113 GBV_ILN_2118 GBV_ILN_2122 GBV_ILN_2129 GBV_ILN_2143 GBV_ILN_2147 GBV_ILN_2148 GBV_ILN_2152 GBV_ILN_2153 GBV_ILN_2190 GBV_ILN_2336 GBV_ILN_2507 GBV_ILN_2522 GBV_ILN_4035 GBV_ILN_4037 GBV_ILN_4112 GBV_ILN_4125 GBV_ILN_4126 GBV_ILN_4242 GBV_ILN_4251 GBV_ILN_4305 GBV_ILN_4313 GBV_ILN_4323 GBV_ILN_4324 GBV_ILN_4325 GBV_ILN_4326 GBV_ILN_4333 GBV_ILN_4334 GBV_ILN_4335 GBV_ILN_4338 GBV_ILN_4393 44.92 Gynäkologie VZ AR 271 27-30 |
| allfieldsGer |
10.1016/j.ejogrb.2022.01.031 doi (DE-627)ELV007601050 (ELSEVIER)S0301-2115(22)00040-9 DE-627 ger DE-627 rda eng 610 VZ 44.92 bkl Zou, Li verfasserin aut Association of IL-17A gene polymorphism rs2275913 with the polycystic ovary syndrome in Yunnan Province, China 2022 nicht spezifiziert zzz rdacontent Computermedien c rdamedia Online-Ressource cr rdacarrier Objective: Polycystic ovary syndrome (PCOS) is a reproductive system disease with high incidence in women of childbearing age. However, the cause and risk factor are not clear. Our study aims to explore whether IL-17A gene polymorphism rs2275913 is associated with the PCOS in women from Yunnan province, China.Materials and methods: From January 2018 to December 2020, we collected 287 specimens from PCOS patients and 279 specimens from healthy women. The rs2275913 in the IL-17A promoter region were detected by PCR-Sanger sequencing. Detailed clinical symptoms were recorded and hormone levels were measured on all enrolled individuals. The risk of rs2275913 to PCOS was evaluated by using a multivariate logistic regression model.Results: The distribution of rs2275913 in the control group and the PCOS group was statistically different. The multivariate logistic regression model showed that rs2275913 could increase the risk of PCOS occurrence. Among PCOS patients, patients carrying rs2275913 A allele increased serum IL-17A levels and could lead to more disturbed hormone levels and have a bit severe clinical manifestation.Conclusion: This case-control study proves that the rs2275913 is a risk factor for the occurrence of PCOS. rs2275913 Polycystic ovary syndrome IL-17A Gene polymorphism Risk Cheng, Yun verfasserin aut Yang, Linna verfasserin aut Zhang, Fen verfasserin aut Zhao, Han verfasserin aut Nian, Lei verfasserin aut Li, Yulan verfasserin aut Feng, Yun verfasserin aut Enthalten in European journal of obstetrics & gynecology and reproductive biology Amsterdam [u.a.] : Elsevier Science, 1971 271, Seite 27-30 Online-Ressource (DE-627)320443469 (DE-600)2005196-7 (DE-576)094142106 1872-7654 nnns volume:271 pages:27-30 GBV_USEFLAG_U GBV_ELV SYSFLAG_U SSG-OLC-PHA GBV_ILN_20 GBV_ILN_22 GBV_ILN_23 GBV_ILN_24 GBV_ILN_31 GBV_ILN_32 GBV_ILN_40 GBV_ILN_60 GBV_ILN_62 GBV_ILN_63 GBV_ILN_65 GBV_ILN_69 GBV_ILN_70 GBV_ILN_73 GBV_ILN_74 GBV_ILN_90 GBV_ILN_95 GBV_ILN_100 GBV_ILN_101 GBV_ILN_105 GBV_ILN_110 GBV_ILN_151 GBV_ILN_224 GBV_ILN_370 GBV_ILN_602 GBV_ILN_702 GBV_ILN_2003 GBV_ILN_2004 GBV_ILN_2005 GBV_ILN_2011 GBV_ILN_2014 GBV_ILN_2015 GBV_ILN_2020 GBV_ILN_2021 GBV_ILN_2025 GBV_ILN_2027 GBV_ILN_2034 GBV_ILN_2038 GBV_ILN_2044 GBV_ILN_2048 GBV_ILN_2049 GBV_ILN_2050 GBV_ILN_2056 GBV_ILN_2059 GBV_ILN_2061 GBV_ILN_2064 GBV_ILN_2065 GBV_ILN_2068 GBV_ILN_2111 GBV_ILN_2112 GBV_ILN_2113 GBV_ILN_2118 GBV_ILN_2122 GBV_ILN_2129 GBV_ILN_2143 GBV_ILN_2147 GBV_ILN_2148 GBV_ILN_2152 GBV_ILN_2153 GBV_ILN_2190 GBV_ILN_2336 GBV_ILN_2507 GBV_ILN_2522 GBV_ILN_4035 GBV_ILN_4037 GBV_ILN_4112 GBV_ILN_4125 GBV_ILN_4126 GBV_ILN_4242 GBV_ILN_4251 GBV_ILN_4305 GBV_ILN_4313 GBV_ILN_4323 GBV_ILN_4324 GBV_ILN_4325 GBV_ILN_4326 GBV_ILN_4333 GBV_ILN_4334 GBV_ILN_4335 GBV_ILN_4338 GBV_ILN_4393 44.92 Gynäkologie VZ AR 271 27-30 |
| allfieldsSound |
10.1016/j.ejogrb.2022.01.031 doi (DE-627)ELV007601050 (ELSEVIER)S0301-2115(22)00040-9 DE-627 ger DE-627 rda eng 610 VZ 44.92 bkl Zou, Li verfasserin aut Association of IL-17A gene polymorphism rs2275913 with the polycystic ovary syndrome in Yunnan Province, China 2022 nicht spezifiziert zzz rdacontent Computermedien c rdamedia Online-Ressource cr rdacarrier Objective: Polycystic ovary syndrome (PCOS) is a reproductive system disease with high incidence in women of childbearing age. However, the cause and risk factor are not clear. Our study aims to explore whether IL-17A gene polymorphism rs2275913 is associated with the PCOS in women from Yunnan province, China.Materials and methods: From January 2018 to December 2020, we collected 287 specimens from PCOS patients and 279 specimens from healthy women. The rs2275913 in the IL-17A promoter region were detected by PCR-Sanger sequencing. Detailed clinical symptoms were recorded and hormone levels were measured on all enrolled individuals. The risk of rs2275913 to PCOS was evaluated by using a multivariate logistic regression model.Results: The distribution of rs2275913 in the control group and the PCOS group was statistically different. The multivariate logistic regression model showed that rs2275913 could increase the risk of PCOS occurrence. Among PCOS patients, patients carrying rs2275913 A allele increased serum IL-17A levels and could lead to more disturbed hormone levels and have a bit severe clinical manifestation.Conclusion: This case-control study proves that the rs2275913 is a risk factor for the occurrence of PCOS. rs2275913 Polycystic ovary syndrome IL-17A Gene polymorphism Risk Cheng, Yun verfasserin aut Yang, Linna verfasserin aut Zhang, Fen verfasserin aut Zhao, Han verfasserin aut Nian, Lei verfasserin aut Li, Yulan verfasserin aut Feng, Yun verfasserin aut Enthalten in European journal of obstetrics & gynecology and reproductive biology Amsterdam [u.a.] : Elsevier Science, 1971 271, Seite 27-30 Online-Ressource (DE-627)320443469 (DE-600)2005196-7 (DE-576)094142106 1872-7654 nnns volume:271 pages:27-30 GBV_USEFLAG_U GBV_ELV SYSFLAG_U SSG-OLC-PHA GBV_ILN_20 GBV_ILN_22 GBV_ILN_23 GBV_ILN_24 GBV_ILN_31 GBV_ILN_32 GBV_ILN_40 GBV_ILN_60 GBV_ILN_62 GBV_ILN_63 GBV_ILN_65 GBV_ILN_69 GBV_ILN_70 GBV_ILN_73 GBV_ILN_74 GBV_ILN_90 GBV_ILN_95 GBV_ILN_100 GBV_ILN_101 GBV_ILN_105 GBV_ILN_110 GBV_ILN_151 GBV_ILN_224 GBV_ILN_370 GBV_ILN_602 GBV_ILN_702 GBV_ILN_2003 GBV_ILN_2004 GBV_ILN_2005 GBV_ILN_2011 GBV_ILN_2014 GBV_ILN_2015 GBV_ILN_2020 GBV_ILN_2021 GBV_ILN_2025 GBV_ILN_2027 GBV_ILN_2034 GBV_ILN_2038 GBV_ILN_2044 GBV_ILN_2048 GBV_ILN_2049 GBV_ILN_2050 GBV_ILN_2056 GBV_ILN_2059 GBV_ILN_2061 GBV_ILN_2064 GBV_ILN_2065 GBV_ILN_2068 GBV_ILN_2111 GBV_ILN_2112 GBV_ILN_2113 GBV_ILN_2118 GBV_ILN_2122 GBV_ILN_2129 GBV_ILN_2143 GBV_ILN_2147 GBV_ILN_2148 GBV_ILN_2152 GBV_ILN_2153 GBV_ILN_2190 GBV_ILN_2336 GBV_ILN_2507 GBV_ILN_2522 GBV_ILN_4035 GBV_ILN_4037 GBV_ILN_4112 GBV_ILN_4125 GBV_ILN_4126 GBV_ILN_4242 GBV_ILN_4251 GBV_ILN_4305 GBV_ILN_4313 GBV_ILN_4323 GBV_ILN_4324 GBV_ILN_4325 GBV_ILN_4326 GBV_ILN_4333 GBV_ILN_4334 GBV_ILN_4335 GBV_ILN_4338 GBV_ILN_4393 44.92 Gynäkologie VZ AR 271 27-30 |
| language |
English |
| source |
Enthalten in European journal of obstetrics & gynecology and reproductive biology 271, Seite 27-30 volume:271 pages:27-30 |
| sourceStr |
Enthalten in European journal of obstetrics & gynecology and reproductive biology 271, Seite 27-30 volume:271 pages:27-30 |
| format_phy_str_mv |
Article |
| bklname |
Gynäkologie |
| institution |
findex.gbv.de |
| topic_facet |
rs2275913 Polycystic ovary syndrome IL-17A Gene polymorphism Risk |
| dewey-raw |
610 |
| isfreeaccess_bool |
false |
| container_title |
European journal of obstetrics & gynecology and reproductive biology |
| authorswithroles_txt_mv |
Zou, Li @@aut@@ Cheng, Yun @@aut@@ Yang, Linna @@aut@@ Zhang, Fen @@aut@@ Zhao, Han @@aut@@ Nian, Lei @@aut@@ Li, Yulan @@aut@@ Feng, Yun @@aut@@ |
| publishDateDaySort_date |
2022-01-01T00:00:00Z |
| hierarchy_top_id |
320443469 |
| dewey-sort |
3610 |
| id |
ELV007601050 |
| language_de |
englisch |
| fullrecord |
<?xml version="1.0" encoding="UTF-8"?><collection xmlns="http://www.loc.gov/MARC21/slim"><record><leader>01000caa a22002652 4500</leader><controlfield tag="001">ELV007601050</controlfield><controlfield tag="003">DE-627</controlfield><controlfield tag="005">20240119093053.0</controlfield><controlfield tag="007">cr uuu---uuuuu</controlfield><controlfield tag="008">230507s2022 xx |||||o 00| ||eng c</controlfield><datafield tag="024" ind1="7" ind2=" "><subfield code="a">10.1016/j.ejogrb.2022.01.031</subfield><subfield code="2">doi</subfield></datafield><datafield tag="035" ind1=" " ind2=" "><subfield code="a">(DE-627)ELV007601050</subfield></datafield><datafield tag="035" ind1=" " ind2=" "><subfield code="a">(ELSEVIER)S0301-2115(22)00040-9</subfield></datafield><datafield tag="040" ind1=" " ind2=" "><subfield code="a">DE-627</subfield><subfield code="b">ger</subfield><subfield code="c">DE-627</subfield><subfield code="e">rda</subfield></datafield><datafield tag="041" ind1=" " ind2=" "><subfield code="a">eng</subfield></datafield><datafield tag="082" ind1="0" ind2="4"><subfield code="a">610</subfield><subfield code="q">VZ</subfield></datafield><datafield tag="084" ind1=" " ind2=" "><subfield code="a">44.92</subfield><subfield code="2">bkl</subfield></datafield><datafield tag="100" ind1="1" ind2=" "><subfield code="a">Zou, Li</subfield><subfield code="e">verfasserin</subfield><subfield code="4">aut</subfield></datafield><datafield tag="245" ind1="1" ind2="0"><subfield code="a">Association of IL-17A gene polymorphism rs2275913 with the polycystic ovary syndrome in Yunnan Province, China</subfield></datafield><datafield tag="264" ind1=" " ind2="1"><subfield code="c">2022</subfield></datafield><datafield tag="336" ind1=" " ind2=" "><subfield code="a">nicht spezifiziert</subfield><subfield code="b">zzz</subfield><subfield code="2">rdacontent</subfield></datafield><datafield tag="337" ind1=" " ind2=" "><subfield code="a">Computermedien</subfield><subfield code="b">c</subfield><subfield code="2">rdamedia</subfield></datafield><datafield tag="338" ind1=" " ind2=" "><subfield code="a">Online-Ressource</subfield><subfield code="b">cr</subfield><subfield code="2">rdacarrier</subfield></datafield><datafield tag="520" ind1=" " ind2=" "><subfield code="a">Objective: Polycystic ovary syndrome (PCOS) is a reproductive system disease with high incidence in women of childbearing age. However, the cause and risk factor are not clear. Our study aims to explore whether IL-17A gene polymorphism rs2275913 is associated with the PCOS in women from Yunnan province, China.Materials and methods: From January 2018 to December 2020, we collected 287 specimens from PCOS patients and 279 specimens from healthy women. The rs2275913 in the IL-17A promoter region were detected by PCR-Sanger sequencing. Detailed clinical symptoms were recorded and hormone levels were measured on all enrolled individuals. The risk of rs2275913 to PCOS was evaluated by using a multivariate logistic regression model.Results: The distribution of rs2275913 in the control group and the PCOS group was statistically different. The multivariate logistic regression model showed that rs2275913 could increase the risk of PCOS occurrence. Among PCOS patients, patients carrying rs2275913 A allele increased serum IL-17A levels and could lead to more disturbed hormone levels and have a bit severe clinical manifestation.Conclusion: This case-control study proves that the rs2275913 is a risk factor for the occurrence of PCOS.</subfield></datafield><datafield tag="650" ind1=" " ind2="4"><subfield code="a">rs2275913</subfield></datafield><datafield tag="650" ind1=" " ind2="4"><subfield code="a">Polycystic ovary syndrome</subfield></datafield><datafield tag="650" ind1=" " ind2="4"><subfield code="a">IL-17A</subfield></datafield><datafield tag="650" ind1=" " ind2="4"><subfield code="a">Gene polymorphism</subfield></datafield><datafield tag="650" ind1=" " ind2="4"><subfield code="a">Risk</subfield></datafield><datafield tag="700" ind1="1" ind2=" "><subfield code="a">Cheng, Yun</subfield><subfield code="e">verfasserin</subfield><subfield code="4">aut</subfield></datafield><datafield tag="700" ind1="1" ind2=" "><subfield code="a">Yang, Linna</subfield><subfield code="e">verfasserin</subfield><subfield code="4">aut</subfield></datafield><datafield tag="700" ind1="1" ind2=" "><subfield code="a">Zhang, Fen</subfield><subfield code="e">verfasserin</subfield><subfield code="4">aut</subfield></datafield><datafield tag="700" ind1="1" ind2=" "><subfield code="a">Zhao, Han</subfield><subfield code="e">verfasserin</subfield><subfield code="4">aut</subfield></datafield><datafield tag="700" ind1="1" ind2=" "><subfield code="a">Nian, Lei</subfield><subfield code="e">verfasserin</subfield><subfield code="4">aut</subfield></datafield><datafield tag="700" ind1="1" ind2=" "><subfield code="a">Li, Yulan</subfield><subfield code="e">verfasserin</subfield><subfield code="4">aut</subfield></datafield><datafield tag="700" ind1="1" ind2=" "><subfield code="a">Feng, Yun</subfield><subfield code="e">verfasserin</subfield><subfield code="4">aut</subfield></datafield><datafield tag="773" ind1="0" ind2="8"><subfield code="i">Enthalten in</subfield><subfield code="t">European journal of obstetrics & gynecology and reproductive biology</subfield><subfield code="d">Amsterdam [u.a.] : Elsevier Science, 1971</subfield><subfield code="g">271, Seite 27-30</subfield><subfield code="h">Online-Ressource</subfield><subfield code="w">(DE-627)320443469</subfield><subfield code="w">(DE-600)2005196-7</subfield><subfield code="w">(DE-576)094142106</subfield><subfield code="x">1872-7654</subfield><subfield code="7">nnns</subfield></datafield><datafield tag="773" ind1="1" ind2="8"><subfield code="g">volume:271</subfield><subfield code="g">pages:27-30</subfield></datafield><datafield tag="912" ind1=" " ind2=" "><subfield code="a">GBV_USEFLAG_U</subfield></datafield><datafield tag="912" ind1=" " ind2=" "><subfield code="a">GBV_ELV</subfield></datafield><datafield tag="912" ind1=" " ind2=" "><subfield code="a">SYSFLAG_U</subfield></datafield><datafield tag="912" ind1=" " ind2=" "><subfield code="a">SSG-OLC-PHA</subfield></datafield><datafield tag="912" ind1=" " ind2=" "><subfield code="a">GBV_ILN_20</subfield></datafield><datafield tag="912" ind1=" " ind2=" "><subfield code="a">GBV_ILN_22</subfield></datafield><datafield tag="912" ind1=" " ind2=" "><subfield code="a">GBV_ILN_23</subfield></datafield><datafield tag="912" ind1=" " ind2=" "><subfield code="a">GBV_ILN_24</subfield></datafield><datafield tag="912" ind1=" " ind2=" "><subfield code="a">GBV_ILN_31</subfield></datafield><datafield tag="912" ind1=" " ind2=" "><subfield code="a">GBV_ILN_32</subfield></datafield><datafield tag="912" ind1=" " ind2=" "><subfield code="a">GBV_ILN_40</subfield></datafield><datafield tag="912" ind1=" " ind2=" "><subfield code="a">GBV_ILN_60</subfield></datafield><datafield tag="912" ind1=" " ind2=" "><subfield code="a">GBV_ILN_62</subfield></datafield><datafield tag="912" ind1=" " ind2=" "><subfield code="a">GBV_ILN_63</subfield></datafield><datafield tag="912" ind1=" " ind2=" "><subfield code="a">GBV_ILN_65</subfield></datafield><datafield tag="912" ind1=" " ind2=" "><subfield code="a">GBV_ILN_69</subfield></datafield><datafield tag="912" ind1=" " ind2=" "><subfield code="a">GBV_ILN_70</subfield></datafield><datafield tag="912" ind1=" " ind2=" "><subfield code="a">GBV_ILN_73</subfield></datafield><datafield tag="912" ind1=" " ind2=" "><subfield code="a">GBV_ILN_74</subfield></datafield><datafield tag="912" ind1=" " ind2=" "><subfield code="a">GBV_ILN_90</subfield></datafield><datafield tag="912" ind1=" " ind2=" "><subfield code="a">GBV_ILN_95</subfield></datafield><datafield tag="912" ind1=" " ind2=" "><subfield code="a">GBV_ILN_100</subfield></datafield><datafield tag="912" ind1=" " ind2=" "><subfield code="a">GBV_ILN_101</subfield></datafield><datafield tag="912" ind1=" " ind2=" "><subfield code="a">GBV_ILN_105</subfield></datafield><datafield tag="912" ind1=" " ind2=" "><subfield code="a">GBV_ILN_110</subfield></datafield><datafield tag="912" ind1=" " ind2=" "><subfield code="a">GBV_ILN_151</subfield></datafield><datafield tag="912" ind1=" " ind2=" "><subfield code="a">GBV_ILN_224</subfield></datafield><datafield tag="912" ind1=" " ind2=" "><subfield code="a">GBV_ILN_370</subfield></datafield><datafield tag="912" ind1=" " ind2=" "><subfield code="a">GBV_ILN_602</subfield></datafield><datafield tag="912" ind1=" " ind2=" "><subfield code="a">GBV_ILN_702</subfield></datafield><datafield tag="912" ind1=" " ind2=" "><subfield code="a">GBV_ILN_2003</subfield></datafield><datafield tag="912" ind1=" " ind2=" "><subfield code="a">GBV_ILN_2004</subfield></datafield><datafield tag="912" ind1=" " ind2=" "><subfield code="a">GBV_ILN_2005</subfield></datafield><datafield tag="912" ind1=" " ind2=" "><subfield code="a">GBV_ILN_2011</subfield></datafield><datafield tag="912" ind1=" " ind2=" "><subfield code="a">GBV_ILN_2014</subfield></datafield><datafield tag="912" ind1=" " ind2=" "><subfield code="a">GBV_ILN_2015</subfield></datafield><datafield tag="912" ind1=" " ind2=" "><subfield code="a">GBV_ILN_2020</subfield></datafield><datafield tag="912" ind1=" " ind2=" "><subfield code="a">GBV_ILN_2021</subfield></datafield><datafield tag="912" ind1=" " ind2=" "><subfield code="a">GBV_ILN_2025</subfield></datafield><datafield tag="912" ind1=" " ind2=" "><subfield code="a">GBV_ILN_2027</subfield></datafield><datafield tag="912" ind1=" " ind2=" "><subfield code="a">GBV_ILN_2034</subfield></datafield><datafield tag="912" ind1=" " ind2=" "><subfield code="a">GBV_ILN_2038</subfield></datafield><datafield tag="912" ind1=" " ind2=" "><subfield code="a">GBV_ILN_2044</subfield></datafield><datafield tag="912" ind1=" " ind2=" "><subfield code="a">GBV_ILN_2048</subfield></datafield><datafield tag="912" ind1=" " ind2=" "><subfield code="a">GBV_ILN_2049</subfield></datafield><datafield tag="912" ind1=" " ind2=" "><subfield code="a">GBV_ILN_2050</subfield></datafield><datafield tag="912" ind1=" " ind2=" "><subfield code="a">GBV_ILN_2056</subfield></datafield><datafield tag="912" ind1=" " ind2=" "><subfield code="a">GBV_ILN_2059</subfield></datafield><datafield tag="912" ind1=" " ind2=" "><subfield code="a">GBV_ILN_2061</subfield></datafield><datafield tag="912" ind1=" " ind2=" "><subfield code="a">GBV_ILN_2064</subfield></datafield><datafield tag="912" ind1=" " ind2=" "><subfield code="a">GBV_ILN_2065</subfield></datafield><datafield tag="912" ind1=" " ind2=" "><subfield code="a">GBV_ILN_2068</subfield></datafield><datafield tag="912" ind1=" " ind2=" "><subfield code="a">GBV_ILN_2111</subfield></datafield><datafield tag="912" ind1=" " ind2=" "><subfield code="a">GBV_ILN_2112</subfield></datafield><datafield tag="912" ind1=" " ind2=" "><subfield code="a">GBV_ILN_2113</subfield></datafield><datafield tag="912" ind1=" " ind2=" "><subfield code="a">GBV_ILN_2118</subfield></datafield><datafield tag="912" ind1=" " ind2=" "><subfield code="a">GBV_ILN_2122</subfield></datafield><datafield tag="912" ind1=" " ind2=" "><subfield code="a">GBV_ILN_2129</subfield></datafield><datafield tag="912" ind1=" " ind2=" "><subfield code="a">GBV_ILN_2143</subfield></datafield><datafield tag="912" ind1=" " ind2=" "><subfield code="a">GBV_ILN_2147</subfield></datafield><datafield tag="912" ind1=" " ind2=" "><subfield code="a">GBV_ILN_2148</subfield></datafield><datafield tag="912" ind1=" " ind2=" "><subfield code="a">GBV_ILN_2152</subfield></datafield><datafield tag="912" ind1=" " ind2=" "><subfield code="a">GBV_ILN_2153</subfield></datafield><datafield tag="912" ind1=" " ind2=" "><subfield code="a">GBV_ILN_2190</subfield></datafield><datafield tag="912" ind1=" " ind2=" "><subfield code="a">GBV_ILN_2336</subfield></datafield><datafield tag="912" ind1=" " ind2=" "><subfield code="a">GBV_ILN_2507</subfield></datafield><datafield tag="912" ind1=" " ind2=" "><subfield code="a">GBV_ILN_2522</subfield></datafield><datafield tag="912" ind1=" " ind2=" "><subfield code="a">GBV_ILN_4035</subfield></datafield><datafield tag="912" ind1=" " ind2=" "><subfield code="a">GBV_ILN_4037</subfield></datafield><datafield tag="912" ind1=" " ind2=" "><subfield code="a">GBV_ILN_4112</subfield></datafield><datafield tag="912" ind1=" " ind2=" "><subfield code="a">GBV_ILN_4125</subfield></datafield><datafield tag="912" ind1=" " ind2=" "><subfield code="a">GBV_ILN_4126</subfield></datafield><datafield tag="912" ind1=" " ind2=" "><subfield code="a">GBV_ILN_4242</subfield></datafield><datafield tag="912" ind1=" " ind2=" "><subfield code="a">GBV_ILN_4251</subfield></datafield><datafield tag="912" ind1=" " ind2=" "><subfield code="a">GBV_ILN_4305</subfield></datafield><datafield tag="912" ind1=" " ind2=" "><subfield code="a">GBV_ILN_4313</subfield></datafield><datafield tag="912" ind1=" " ind2=" "><subfield code="a">GBV_ILN_4323</subfield></datafield><datafield tag="912" ind1=" " ind2=" "><subfield code="a">GBV_ILN_4324</subfield></datafield><datafield tag="912" ind1=" " ind2=" "><subfield code="a">GBV_ILN_4325</subfield></datafield><datafield tag="912" ind1=" " ind2=" "><subfield code="a">GBV_ILN_4326</subfield></datafield><datafield tag="912" ind1=" " ind2=" "><subfield code="a">GBV_ILN_4333</subfield></datafield><datafield tag="912" ind1=" " ind2=" "><subfield code="a">GBV_ILN_4334</subfield></datafield><datafield tag="912" ind1=" " ind2=" "><subfield code="a">GBV_ILN_4335</subfield></datafield><datafield tag="912" ind1=" " ind2=" "><subfield code="a">GBV_ILN_4338</subfield></datafield><datafield tag="912" ind1=" " ind2=" "><subfield code="a">GBV_ILN_4393</subfield></datafield><datafield tag="936" ind1="b" ind2="k"><subfield code="a">44.92</subfield><subfield code="j">Gynäkologie</subfield><subfield code="q">VZ</subfield></datafield><datafield tag="951" ind1=" " ind2=" "><subfield code="a">AR</subfield></datafield><datafield tag="952" ind1=" " ind2=" "><subfield code="d">271</subfield><subfield code="h">27-30</subfield></datafield></record></collection>
|
| author |
Zou, Li |
| spellingShingle |
Zou, Li ddc 610 bkl 44.92 misc rs2275913 misc Polycystic ovary syndrome misc IL-17A misc Gene polymorphism misc Risk Association of IL-17A gene polymorphism rs2275913 with the polycystic ovary syndrome in Yunnan Province, China |
| authorStr |
Zou, Li |
| ppnlink_with_tag_str_mv |
@@773@@(DE-627)320443469 |
| format |
electronic Article |
| dewey-ones |
610 - Medicine & health |
| delete_txt_mv |
keep |
| author_role |
aut aut aut aut aut aut aut aut |
| collection |
elsevier |
| remote_str |
true |
| illustrated |
Not Illustrated |
| issn |
1872-7654 |
| topic_title |
610 VZ 44.92 bkl Association of IL-17A gene polymorphism rs2275913 with the polycystic ovary syndrome in Yunnan Province, China rs2275913 Polycystic ovary syndrome IL-17A Gene polymorphism Risk |
| topic |
ddc 610 bkl 44.92 misc rs2275913 misc Polycystic ovary syndrome misc IL-17A misc Gene polymorphism misc Risk |
| topic_unstemmed |
ddc 610 bkl 44.92 misc rs2275913 misc Polycystic ovary syndrome misc IL-17A misc Gene polymorphism misc Risk |
| topic_browse |
ddc 610 bkl 44.92 misc rs2275913 misc Polycystic ovary syndrome misc IL-17A misc Gene polymorphism misc Risk |
| format_facet |
Elektronische Aufsätze Aufsätze Elektronische Ressource |
| format_main_str_mv |
Text Zeitschrift/Artikel |
| carriertype_str_mv |
cr |
| hierarchy_parent_title |
European journal of obstetrics & gynecology and reproductive biology |
| hierarchy_parent_id |
320443469 |
| dewey-tens |
610 - Medicine & health |
| hierarchy_top_title |
European journal of obstetrics & gynecology and reproductive biology |
| isfreeaccess_txt |
false |
| familylinks_str_mv |
(DE-627)320443469 (DE-600)2005196-7 (DE-576)094142106 |
| title |
Association of IL-17A gene polymorphism rs2275913 with the polycystic ovary syndrome in Yunnan Province, China |
| ctrlnum |
(DE-627)ELV007601050 (ELSEVIER)S0301-2115(22)00040-9 |
| title_full |
Association of IL-17A gene polymorphism rs2275913 with the polycystic ovary syndrome in Yunnan Province, China |
| author_sort |
Zou, Li |
| journal |
European journal of obstetrics & gynecology and reproductive biology |
| journalStr |
European journal of obstetrics & gynecology and reproductive biology |
| lang_code |
eng |
| isOA_bool |
false |
| dewey-hundreds |
600 - Technology |
| recordtype |
marc |
| publishDateSort |
2022 |
| contenttype_str_mv |
zzz |
| container_start_page |
27 |
| author_browse |
Zou, Li Cheng, Yun Yang, Linna Zhang, Fen Zhao, Han Nian, Lei Li, Yulan Feng, Yun |
| container_volume |
271 |
| class |
610 VZ 44.92 bkl |
| format_se |
Elektronische Aufsätze |
| author-letter |
Zou, Li |
| doi_str_mv |
10.1016/j.ejogrb.2022.01.031 |
| dewey-full |
610 |
| author2-role |
verfasserin |
| title_sort |
association of il-17a gene polymorphism rs2275913 with the polycystic ovary syndrome in yunnan province, china |
| title_auth |
Association of IL-17A gene polymorphism rs2275913 with the polycystic ovary syndrome in Yunnan Province, China |
| abstract |
Objective: Polycystic ovary syndrome (PCOS) is a reproductive system disease with high incidence in women of childbearing age. However, the cause and risk factor are not clear. Our study aims to explore whether IL-17A gene polymorphism rs2275913 is associated with the PCOS in women from Yunnan province, China.Materials and methods: From January 2018 to December 2020, we collected 287 specimens from PCOS patients and 279 specimens from healthy women. The rs2275913 in the IL-17A promoter region were detected by PCR-Sanger sequencing. Detailed clinical symptoms were recorded and hormone levels were measured on all enrolled individuals. The risk of rs2275913 to PCOS was evaluated by using a multivariate logistic regression model.Results: The distribution of rs2275913 in the control group and the PCOS group was statistically different. The multivariate logistic regression model showed that rs2275913 could increase the risk of PCOS occurrence. Among PCOS patients, patients carrying rs2275913 A allele increased serum IL-17A levels and could lead to more disturbed hormone levels and have a bit severe clinical manifestation.Conclusion: This case-control study proves that the rs2275913 is a risk factor for the occurrence of PCOS. |
| abstractGer |
Objective: Polycystic ovary syndrome (PCOS) is a reproductive system disease with high incidence in women of childbearing age. However, the cause and risk factor are not clear. Our study aims to explore whether IL-17A gene polymorphism rs2275913 is associated with the PCOS in women from Yunnan province, China.Materials and methods: From January 2018 to December 2020, we collected 287 specimens from PCOS patients and 279 specimens from healthy women. The rs2275913 in the IL-17A promoter region were detected by PCR-Sanger sequencing. Detailed clinical symptoms were recorded and hormone levels were measured on all enrolled individuals. The risk of rs2275913 to PCOS was evaluated by using a multivariate logistic regression model.Results: The distribution of rs2275913 in the control group and the PCOS group was statistically different. The multivariate logistic regression model showed that rs2275913 could increase the risk of PCOS occurrence. Among PCOS patients, patients carrying rs2275913 A allele increased serum IL-17A levels and could lead to more disturbed hormone levels and have a bit severe clinical manifestation.Conclusion: This case-control study proves that the rs2275913 is a risk factor for the occurrence of PCOS. |
| abstract_unstemmed |
Objective: Polycystic ovary syndrome (PCOS) is a reproductive system disease with high incidence in women of childbearing age. However, the cause and risk factor are not clear. Our study aims to explore whether IL-17A gene polymorphism rs2275913 is associated with the PCOS in women from Yunnan province, China.Materials and methods: From January 2018 to December 2020, we collected 287 specimens from PCOS patients and 279 specimens from healthy women. The rs2275913 in the IL-17A promoter region were detected by PCR-Sanger sequencing. Detailed clinical symptoms were recorded and hormone levels were measured on all enrolled individuals. The risk of rs2275913 to PCOS was evaluated by using a multivariate logistic regression model.Results: The distribution of rs2275913 in the control group and the PCOS group was statistically different. The multivariate logistic regression model showed that rs2275913 could increase the risk of PCOS occurrence. Among PCOS patients, patients carrying rs2275913 A allele increased serum IL-17A levels and could lead to more disturbed hormone levels and have a bit severe clinical manifestation.Conclusion: This case-control study proves that the rs2275913 is a risk factor for the occurrence of PCOS. |
| collection_details |
GBV_USEFLAG_U GBV_ELV SYSFLAG_U SSG-OLC-PHA GBV_ILN_20 GBV_ILN_22 GBV_ILN_23 GBV_ILN_24 GBV_ILN_31 GBV_ILN_32 GBV_ILN_40 GBV_ILN_60 GBV_ILN_62 GBV_ILN_63 GBV_ILN_65 GBV_ILN_69 GBV_ILN_70 GBV_ILN_73 GBV_ILN_74 GBV_ILN_90 GBV_ILN_95 GBV_ILN_100 GBV_ILN_101 GBV_ILN_105 GBV_ILN_110 GBV_ILN_151 GBV_ILN_224 GBV_ILN_370 GBV_ILN_602 GBV_ILN_702 GBV_ILN_2003 GBV_ILN_2004 GBV_ILN_2005 GBV_ILN_2011 GBV_ILN_2014 GBV_ILN_2015 GBV_ILN_2020 GBV_ILN_2021 GBV_ILN_2025 GBV_ILN_2027 GBV_ILN_2034 GBV_ILN_2038 GBV_ILN_2044 GBV_ILN_2048 GBV_ILN_2049 GBV_ILN_2050 GBV_ILN_2056 GBV_ILN_2059 GBV_ILN_2061 GBV_ILN_2064 GBV_ILN_2065 GBV_ILN_2068 GBV_ILN_2111 GBV_ILN_2112 GBV_ILN_2113 GBV_ILN_2118 GBV_ILN_2122 GBV_ILN_2129 GBV_ILN_2143 GBV_ILN_2147 GBV_ILN_2148 GBV_ILN_2152 GBV_ILN_2153 GBV_ILN_2190 GBV_ILN_2336 GBV_ILN_2507 GBV_ILN_2522 GBV_ILN_4035 GBV_ILN_4037 GBV_ILN_4112 GBV_ILN_4125 GBV_ILN_4126 GBV_ILN_4242 GBV_ILN_4251 GBV_ILN_4305 GBV_ILN_4313 GBV_ILN_4323 GBV_ILN_4324 GBV_ILN_4325 GBV_ILN_4326 GBV_ILN_4333 GBV_ILN_4334 GBV_ILN_4335 GBV_ILN_4338 GBV_ILN_4393 |
| title_short |
Association of IL-17A gene polymorphism rs2275913 with the polycystic ovary syndrome in Yunnan Province, China |
| remote_bool |
true |
| author2 |
Cheng, Yun Yang, Linna Zhang, Fen Zhao, Han Nian, Lei Li, Yulan Feng, Yun |
| author2Str |
Cheng, Yun Yang, Linna Zhang, Fen Zhao, Han Nian, Lei Li, Yulan Feng, Yun |
| ppnlink |
320443469 |
| mediatype_str_mv |
c |
| isOA_txt |
false |
| hochschulschrift_bool |
false |
| doi_str |
10.1016/j.ejogrb.2022.01.031 |
| up_date |
2024-07-06T16:49:28.002Z |
| _version_ |
1803849111181459456 |
| fullrecord_marcxml |
<?xml version="1.0" encoding="UTF-8"?><collection xmlns="http://www.loc.gov/MARC21/slim"><record><leader>01000caa a22002652 4500</leader><controlfield tag="001">ELV007601050</controlfield><controlfield tag="003">DE-627</controlfield><controlfield tag="005">20240119093053.0</controlfield><controlfield tag="007">cr uuu---uuuuu</controlfield><controlfield tag="008">230507s2022 xx |||||o 00| ||eng c</controlfield><datafield tag="024" ind1="7" ind2=" "><subfield code="a">10.1016/j.ejogrb.2022.01.031</subfield><subfield code="2">doi</subfield></datafield><datafield tag="035" ind1=" " ind2=" "><subfield code="a">(DE-627)ELV007601050</subfield></datafield><datafield tag="035" ind1=" " ind2=" "><subfield code="a">(ELSEVIER)S0301-2115(22)00040-9</subfield></datafield><datafield tag="040" ind1=" " ind2=" "><subfield code="a">DE-627</subfield><subfield code="b">ger</subfield><subfield code="c">DE-627</subfield><subfield code="e">rda</subfield></datafield><datafield tag="041" ind1=" " ind2=" "><subfield code="a">eng</subfield></datafield><datafield tag="082" ind1="0" ind2="4"><subfield code="a">610</subfield><subfield code="q">VZ</subfield></datafield><datafield tag="084" ind1=" " ind2=" "><subfield code="a">44.92</subfield><subfield code="2">bkl</subfield></datafield><datafield tag="100" ind1="1" ind2=" "><subfield code="a">Zou, Li</subfield><subfield code="e">verfasserin</subfield><subfield code="4">aut</subfield></datafield><datafield tag="245" ind1="1" ind2="0"><subfield code="a">Association of IL-17A gene polymorphism rs2275913 with the polycystic ovary syndrome in Yunnan Province, China</subfield></datafield><datafield tag="264" ind1=" " ind2="1"><subfield code="c">2022</subfield></datafield><datafield tag="336" ind1=" " ind2=" "><subfield code="a">nicht spezifiziert</subfield><subfield code="b">zzz</subfield><subfield code="2">rdacontent</subfield></datafield><datafield tag="337" ind1=" " ind2=" "><subfield code="a">Computermedien</subfield><subfield code="b">c</subfield><subfield code="2">rdamedia</subfield></datafield><datafield tag="338" ind1=" " ind2=" "><subfield code="a">Online-Ressource</subfield><subfield code="b">cr</subfield><subfield code="2">rdacarrier</subfield></datafield><datafield tag="520" ind1=" " ind2=" "><subfield code="a">Objective: Polycystic ovary syndrome (PCOS) is a reproductive system disease with high incidence in women of childbearing age. However, the cause and risk factor are not clear. Our study aims to explore whether IL-17A gene polymorphism rs2275913 is associated with the PCOS in women from Yunnan province, China.Materials and methods: From January 2018 to December 2020, we collected 287 specimens from PCOS patients and 279 specimens from healthy women. The rs2275913 in the IL-17A promoter region were detected by PCR-Sanger sequencing. Detailed clinical symptoms were recorded and hormone levels were measured on all enrolled individuals. The risk of rs2275913 to PCOS was evaluated by using a multivariate logistic regression model.Results: The distribution of rs2275913 in the control group and the PCOS group was statistically different. The multivariate logistic regression model showed that rs2275913 could increase the risk of PCOS occurrence. Among PCOS patients, patients carrying rs2275913 A allele increased serum IL-17A levels and could lead to more disturbed hormone levels and have a bit severe clinical manifestation.Conclusion: This case-control study proves that the rs2275913 is a risk factor for the occurrence of PCOS.</subfield></datafield><datafield tag="650" ind1=" " ind2="4"><subfield code="a">rs2275913</subfield></datafield><datafield tag="650" ind1=" " ind2="4"><subfield code="a">Polycystic ovary syndrome</subfield></datafield><datafield tag="650" ind1=" " ind2="4"><subfield code="a">IL-17A</subfield></datafield><datafield tag="650" ind1=" " ind2="4"><subfield code="a">Gene polymorphism</subfield></datafield><datafield tag="650" ind1=" " ind2="4"><subfield code="a">Risk</subfield></datafield><datafield tag="700" ind1="1" ind2=" "><subfield code="a">Cheng, Yun</subfield><subfield code="e">verfasserin</subfield><subfield code="4">aut</subfield></datafield><datafield tag="700" ind1="1" ind2=" "><subfield code="a">Yang, Linna</subfield><subfield code="e">verfasserin</subfield><subfield code="4">aut</subfield></datafield><datafield tag="700" ind1="1" ind2=" "><subfield code="a">Zhang, Fen</subfield><subfield code="e">verfasserin</subfield><subfield code="4">aut</subfield></datafield><datafield tag="700" ind1="1" ind2=" "><subfield code="a">Zhao, Han</subfield><subfield code="e">verfasserin</subfield><subfield code="4">aut</subfield></datafield><datafield tag="700" ind1="1" ind2=" "><subfield code="a">Nian, Lei</subfield><subfield code="e">verfasserin</subfield><subfield code="4">aut</subfield></datafield><datafield tag="700" ind1="1" ind2=" "><subfield code="a">Li, Yulan</subfield><subfield code="e">verfasserin</subfield><subfield code="4">aut</subfield></datafield><datafield tag="700" ind1="1" ind2=" "><subfield code="a">Feng, Yun</subfield><subfield code="e">verfasserin</subfield><subfield code="4">aut</subfield></datafield><datafield tag="773" ind1="0" ind2="8"><subfield code="i">Enthalten in</subfield><subfield code="t">European journal of obstetrics & gynecology and reproductive biology</subfield><subfield code="d">Amsterdam [u.a.] : Elsevier Science, 1971</subfield><subfield code="g">271, Seite 27-30</subfield><subfield code="h">Online-Ressource</subfield><subfield code="w">(DE-627)320443469</subfield><subfield code="w">(DE-600)2005196-7</subfield><subfield code="w">(DE-576)094142106</subfield><subfield code="x">1872-7654</subfield><subfield code="7">nnns</subfield></datafield><datafield tag="773" ind1="1" ind2="8"><subfield code="g">volume:271</subfield><subfield code="g">pages:27-30</subfield></datafield><datafield tag="912" ind1=" " ind2=" "><subfield code="a">GBV_USEFLAG_U</subfield></datafield><datafield tag="912" ind1=" " ind2=" "><subfield code="a">GBV_ELV</subfield></datafield><datafield tag="912" ind1=" " ind2=" "><subfield code="a">SYSFLAG_U</subfield></datafield><datafield tag="912" ind1=" " ind2=" "><subfield code="a">SSG-OLC-PHA</subfield></datafield><datafield tag="912" ind1=" " ind2=" "><subfield code="a">GBV_ILN_20</subfield></datafield><datafield tag="912" ind1=" " ind2=" "><subfield code="a">GBV_ILN_22</subfield></datafield><datafield tag="912" ind1=" " ind2=" "><subfield code="a">GBV_ILN_23</subfield></datafield><datafield tag="912" ind1=" " ind2=" "><subfield code="a">GBV_ILN_24</subfield></datafield><datafield tag="912" ind1=" " ind2=" "><subfield code="a">GBV_ILN_31</subfield></datafield><datafield tag="912" ind1=" " ind2=" "><subfield code="a">GBV_ILN_32</subfield></datafield><datafield tag="912" ind1=" " ind2=" "><subfield code="a">GBV_ILN_40</subfield></datafield><datafield tag="912" ind1=" " ind2=" "><subfield code="a">GBV_ILN_60</subfield></datafield><datafield tag="912" ind1=" " ind2=" "><subfield code="a">GBV_ILN_62</subfield></datafield><datafield tag="912" ind1=" " ind2=" "><subfield code="a">GBV_ILN_63</subfield></datafield><datafield tag="912" ind1=" " ind2=" "><subfield code="a">GBV_ILN_65</subfield></datafield><datafield tag="912" ind1=" " ind2=" "><subfield code="a">GBV_ILN_69</subfield></datafield><datafield tag="912" ind1=" " ind2=" "><subfield code="a">GBV_ILN_70</subfield></datafield><datafield tag="912" ind1=" " ind2=" "><subfield code="a">GBV_ILN_73</subfield></datafield><datafield tag="912" ind1=" " ind2=" "><subfield code="a">GBV_ILN_74</subfield></datafield><datafield tag="912" ind1=" " ind2=" "><subfield code="a">GBV_ILN_90</subfield></datafield><datafield tag="912" ind1=" " ind2=" "><subfield code="a">GBV_ILN_95</subfield></datafield><datafield tag="912" ind1=" " ind2=" "><subfield code="a">GBV_ILN_100</subfield></datafield><datafield tag="912" ind1=" " ind2=" "><subfield code="a">GBV_ILN_101</subfield></datafield><datafield tag="912" ind1=" " ind2=" "><subfield code="a">GBV_ILN_105</subfield></datafield><datafield tag="912" ind1=" " ind2=" "><subfield code="a">GBV_ILN_110</subfield></datafield><datafield tag="912" ind1=" " ind2=" "><subfield code="a">GBV_ILN_151</subfield></datafield><datafield tag="912" ind1=" " ind2=" "><subfield code="a">GBV_ILN_224</subfield></datafield><datafield tag="912" ind1=" " ind2=" "><subfield code="a">GBV_ILN_370</subfield></datafield><datafield tag="912" ind1=" " ind2=" "><subfield code="a">GBV_ILN_602</subfield></datafield><datafield tag="912" ind1=" " ind2=" "><subfield code="a">GBV_ILN_702</subfield></datafield><datafield tag="912" ind1=" " ind2=" "><subfield code="a">GBV_ILN_2003</subfield></datafield><datafield tag="912" ind1=" " ind2=" "><subfield code="a">GBV_ILN_2004</subfield></datafield><datafield tag="912" ind1=" " ind2=" "><subfield code="a">GBV_ILN_2005</subfield></datafield><datafield tag="912" ind1=" " ind2=" "><subfield code="a">GBV_ILN_2011</subfield></datafield><datafield tag="912" ind1=" " ind2=" "><subfield code="a">GBV_ILN_2014</subfield></datafield><datafield tag="912" ind1=" " ind2=" "><subfield code="a">GBV_ILN_2015</subfield></datafield><datafield tag="912" ind1=" " ind2=" "><subfield code="a">GBV_ILN_2020</subfield></datafield><datafield tag="912" ind1=" " ind2=" "><subfield code="a">GBV_ILN_2021</subfield></datafield><datafield tag="912" ind1=" " ind2=" "><subfield code="a">GBV_ILN_2025</subfield></datafield><datafield tag="912" ind1=" " ind2=" "><subfield code="a">GBV_ILN_2027</subfield></datafield><datafield tag="912" ind1=" " ind2=" "><subfield code="a">GBV_ILN_2034</subfield></datafield><datafield tag="912" ind1=" " ind2=" "><subfield code="a">GBV_ILN_2038</subfield></datafield><datafield tag="912" ind1=" " ind2=" "><subfield code="a">GBV_ILN_2044</subfield></datafield><datafield tag="912" ind1=" " ind2=" "><subfield code="a">GBV_ILN_2048</subfield></datafield><datafield tag="912" ind1=" " ind2=" "><subfield code="a">GBV_ILN_2049</subfield></datafield><datafield tag="912" ind1=" " ind2=" "><subfield code="a">GBV_ILN_2050</subfield></datafield><datafield tag="912" ind1=" " ind2=" "><subfield code="a">GBV_ILN_2056</subfield></datafield><datafield tag="912" ind1=" " ind2=" "><subfield code="a">GBV_ILN_2059</subfield></datafield><datafield tag="912" ind1=" " ind2=" "><subfield code="a">GBV_ILN_2061</subfield></datafield><datafield tag="912" ind1=" " ind2=" "><subfield code="a">GBV_ILN_2064</subfield></datafield><datafield tag="912" ind1=" " ind2=" "><subfield code="a">GBV_ILN_2065</subfield></datafield><datafield tag="912" ind1=" " ind2=" "><subfield code="a">GBV_ILN_2068</subfield></datafield><datafield tag="912" ind1=" " ind2=" "><subfield code="a">GBV_ILN_2111</subfield></datafield><datafield tag="912" ind1=" " ind2=" "><subfield code="a">GBV_ILN_2112</subfield></datafield><datafield tag="912" ind1=" " ind2=" "><subfield code="a">GBV_ILN_2113</subfield></datafield><datafield tag="912" ind1=" " ind2=" "><subfield code="a">GBV_ILN_2118</subfield></datafield><datafield tag="912" ind1=" " ind2=" "><subfield code="a">GBV_ILN_2122</subfield></datafield><datafield tag="912" ind1=" " ind2=" "><subfield code="a">GBV_ILN_2129</subfield></datafield><datafield tag="912" ind1=" " ind2=" "><subfield code="a">GBV_ILN_2143</subfield></datafield><datafield tag="912" ind1=" " ind2=" "><subfield code="a">GBV_ILN_2147</subfield></datafield><datafield tag="912" ind1=" " ind2=" "><subfield code="a">GBV_ILN_2148</subfield></datafield><datafield tag="912" ind1=" " ind2=" "><subfield code="a">GBV_ILN_2152</subfield></datafield><datafield tag="912" ind1=" " ind2=" "><subfield code="a">GBV_ILN_2153</subfield></datafield><datafield tag="912" ind1=" " ind2=" "><subfield code="a">GBV_ILN_2190</subfield></datafield><datafield tag="912" ind1=" " ind2=" "><subfield code="a">GBV_ILN_2336</subfield></datafield><datafield tag="912" ind1=" " ind2=" "><subfield code="a">GBV_ILN_2507</subfield></datafield><datafield tag="912" ind1=" " ind2=" "><subfield code="a">GBV_ILN_2522</subfield></datafield><datafield tag="912" ind1=" " ind2=" "><subfield code="a">GBV_ILN_4035</subfield></datafield><datafield tag="912" ind1=" " ind2=" "><subfield code="a">GBV_ILN_4037</subfield></datafield><datafield tag="912" ind1=" " ind2=" "><subfield code="a">GBV_ILN_4112</subfield></datafield><datafield tag="912" ind1=" " ind2=" "><subfield code="a">GBV_ILN_4125</subfield></datafield><datafield tag="912" ind1=" " ind2=" "><subfield code="a">GBV_ILN_4126</subfield></datafield><datafield tag="912" ind1=" " ind2=" "><subfield code="a">GBV_ILN_4242</subfield></datafield><datafield tag="912" ind1=" " ind2=" "><subfield code="a">GBV_ILN_4251</subfield></datafield><datafield tag="912" ind1=" " ind2=" "><subfield code="a">GBV_ILN_4305</subfield></datafield><datafield tag="912" ind1=" " ind2=" "><subfield code="a">GBV_ILN_4313</subfield></datafield><datafield tag="912" ind1=" " ind2=" "><subfield code="a">GBV_ILN_4323</subfield></datafield><datafield tag="912" ind1=" " ind2=" "><subfield code="a">GBV_ILN_4324</subfield></datafield><datafield tag="912" ind1=" " ind2=" "><subfield code="a">GBV_ILN_4325</subfield></datafield><datafield tag="912" ind1=" " ind2=" "><subfield code="a">GBV_ILN_4326</subfield></datafield><datafield tag="912" ind1=" " ind2=" "><subfield code="a">GBV_ILN_4333</subfield></datafield><datafield tag="912" ind1=" " ind2=" "><subfield code="a">GBV_ILN_4334</subfield></datafield><datafield tag="912" ind1=" " ind2=" "><subfield code="a">GBV_ILN_4335</subfield></datafield><datafield tag="912" ind1=" " ind2=" "><subfield code="a">GBV_ILN_4338</subfield></datafield><datafield tag="912" ind1=" " ind2=" "><subfield code="a">GBV_ILN_4393</subfield></datafield><datafield tag="936" ind1="b" ind2="k"><subfield code="a">44.92</subfield><subfield code="j">Gynäkologie</subfield><subfield code="q">VZ</subfield></datafield><datafield tag="951" ind1=" " ind2=" "><subfield code="a">AR</subfield></datafield><datafield tag="952" ind1=" " ind2=" "><subfield code="d">271</subfield><subfield code="h">27-30</subfield></datafield></record></collection>
|
| score |
7.399496 |