Comprehensive phenotyping of circulating immune cell subsets in people living with HIV
Systemic chronic inflammation and immune dysfunction are recognized as drivers of the development of non-AIDS related comorbidities (NARCs) in people living with HIV (PLHIV). In order to lower the risk of NARCs, it is critical to elucidate what is the contribution of alterations in the composition a...
Ausführliche Beschreibung
Autor*in: |
Navas, Adriana [verfasserIn] Van de Wijer, Lisa [verfasserIn] Jacobs-Cleophas, Maartje [verfasserIn] Schimmel-Naber, A. Marlies [verfasserIn] van Cranenbroek, Bram [verfasserIn] van der Heijden, Wouter A. [verfasserIn] van der Lei, Roelof J. [verfasserIn] Vergara, Zaida [verfasserIn] Netea, Mihai G. [verfasserIn] van der Ven, André J.A.M. [verfasserIn] Kapinsky, Michael [verfasserIn] Koenen, Hans J.P.M. [verfasserIn] Joosten, Leo A.B. [verfasserIn] |
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Format: |
E-Artikel |
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Sprache: |
Englisch |
Erschienen: |
2022 |
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Schlagwörter: |
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Übergeordnetes Werk: |
Enthalten in: Journal of immunological methods - Amsterdam [u.a.] : Elsevier Science, 1971, 507 |
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Übergeordnetes Werk: |
volume:507 |
DOI / URN: |
10.1016/j.jim.2022.113307 |
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Katalog-ID: |
ELV008177597 |
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100 | 1 | |a Navas, Adriana |e verfasserin |4 aut | |
245 | 1 | 0 | |a Comprehensive phenotyping of circulating immune cell subsets in people living with HIV |
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520 | |a Systemic chronic inflammation and immune dysfunction are recognized as drivers of the development of non-AIDS related comorbidities (NARCs) in people living with HIV (PLHIV). In order to lower the risk of NARCs, it is critical to elucidate what is the contribution of alterations in the composition and function of circulating immune cells to NARCs-related pathogenesis. Findings from previous immunophenotyping studies in PLHIV are highly heterogeneous and it is not fully understood to what extent phenotypic changes on immune cells play a role in the dysregulated inflammatory response observed. | ||
650 | 4 | |a Immunophenotyping | |
650 | 4 | |a Non-AIDS-related comorbidities (NARCs) | |
650 | 4 | |a HIV/AIDS | |
650 | 4 | |a Flow cytometry | |
650 | 4 | |a People living with HIV (PLHIV) | |
700 | 1 | |a Van de Wijer, Lisa |e verfasserin |4 aut | |
700 | 1 | |a Jacobs-Cleophas, Maartje |e verfasserin |4 aut | |
700 | 1 | |a Schimmel-Naber, A. Marlies |e verfasserin |4 aut | |
700 | 1 | |a van Cranenbroek, Bram |e verfasserin |4 aut | |
700 | 1 | |a van der Heijden, Wouter A. |e verfasserin |4 aut | |
700 | 1 | |a van der Lei, Roelof J. |e verfasserin |4 aut | |
700 | 1 | |a Vergara, Zaida |e verfasserin |4 aut | |
700 | 1 | |a Netea, Mihai G. |e verfasserin |4 aut | |
700 | 1 | |a van der Ven, André J.A.M. |e verfasserin |4 aut | |
700 | 1 | |a Kapinsky, Michael |e verfasserin |4 aut | |
700 | 1 | |a Koenen, Hans J.P.M. |e verfasserin |4 aut | |
700 | 1 | |a Joosten, Leo A.B. |e verfasserin |4 aut | |
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2022 |
allfields |
10.1016/j.jim.2022.113307 doi (DE-627)ELV008177597 (ELSEVIER)S0022-1759(22)00094-1 DE-627 ger DE-627 rda eng 610 DE-600 44.45 bkl Navas, Adriana verfasserin aut Comprehensive phenotyping of circulating immune cell subsets in people living with HIV 2022 nicht spezifiziert zzz rdacontent Computermedien c rdamedia Online-Ressource cr rdacarrier Systemic chronic inflammation and immune dysfunction are recognized as drivers of the development of non-AIDS related comorbidities (NARCs) in people living with HIV (PLHIV). In order to lower the risk of NARCs, it is critical to elucidate what is the contribution of alterations in the composition and function of circulating immune cells to NARCs-related pathogenesis. Findings from previous immunophenotyping studies in PLHIV are highly heterogeneous and it is not fully understood to what extent phenotypic changes on immune cells play a role in the dysregulated inflammatory response observed. Immunophenotyping Non-AIDS-related comorbidities (NARCs) HIV/AIDS Flow cytometry People living with HIV (PLHIV) Van de Wijer, Lisa verfasserin aut Jacobs-Cleophas, Maartje verfasserin aut Schimmel-Naber, A. Marlies verfasserin aut van Cranenbroek, Bram verfasserin aut van der Heijden, Wouter A. verfasserin aut van der Lei, Roelof J. verfasserin aut Vergara, Zaida verfasserin aut Netea, Mihai G. verfasserin aut van der Ven, André J.A.M. verfasserin aut Kapinsky, Michael verfasserin aut Koenen, Hans J.P.M. verfasserin aut Joosten, Leo A.B. verfasserin aut Enthalten in Journal of immunological methods Amsterdam [u.a.] : Elsevier Science, 1971 507 Online-Ressource (DE-627)306659751 (DE-600)1500495-8 (DE-576)081986386 1872-7905 nnns volume:507 GBV_USEFLAG_U SYSFLAG_U GBV_ELV SSG-OLC-PHA GBV_ILN_20 GBV_ILN_22 GBV_ILN_23 GBV_ILN_24 GBV_ILN_31 GBV_ILN_32 GBV_ILN_40 GBV_ILN_60 GBV_ILN_62 GBV_ILN_63 GBV_ILN_65 GBV_ILN_69 GBV_ILN_70 GBV_ILN_73 GBV_ILN_74 GBV_ILN_90 GBV_ILN_95 GBV_ILN_100 GBV_ILN_101 GBV_ILN_105 GBV_ILN_110 GBV_ILN_151 GBV_ILN_224 GBV_ILN_370 GBV_ILN_602 GBV_ILN_702 GBV_ILN_2003 GBV_ILN_2004 GBV_ILN_2005 GBV_ILN_2011 GBV_ILN_2014 GBV_ILN_2015 GBV_ILN_2020 GBV_ILN_2021 GBV_ILN_2025 GBV_ILN_2027 GBV_ILN_2034 GBV_ILN_2038 GBV_ILN_2044 GBV_ILN_2048 GBV_ILN_2049 GBV_ILN_2050 GBV_ILN_2056 GBV_ILN_2059 GBV_ILN_2061 GBV_ILN_2064 GBV_ILN_2065 GBV_ILN_2068 GBV_ILN_2111 GBV_ILN_2112 GBV_ILN_2113 GBV_ILN_2118 GBV_ILN_2122 GBV_ILN_2129 GBV_ILN_2143 GBV_ILN_2147 GBV_ILN_2148 GBV_ILN_2152 GBV_ILN_2153 GBV_ILN_2190 GBV_ILN_2336 GBV_ILN_2507 GBV_ILN_2522 GBV_ILN_4035 GBV_ILN_4037 GBV_ILN_4112 GBV_ILN_4125 GBV_ILN_4126 GBV_ILN_4242 GBV_ILN_4251 GBV_ILN_4305 GBV_ILN_4313 GBV_ILN_4323 GBV_ILN_4324 GBV_ILN_4325 GBV_ILN_4326 GBV_ILN_4333 GBV_ILN_4334 GBV_ILN_4335 GBV_ILN_4338 GBV_ILN_4393 44.45 Immunologie AR 507 |
spelling |
10.1016/j.jim.2022.113307 doi (DE-627)ELV008177597 (ELSEVIER)S0022-1759(22)00094-1 DE-627 ger DE-627 rda eng 610 DE-600 44.45 bkl Navas, Adriana verfasserin aut Comprehensive phenotyping of circulating immune cell subsets in people living with HIV 2022 nicht spezifiziert zzz rdacontent Computermedien c rdamedia Online-Ressource cr rdacarrier Systemic chronic inflammation and immune dysfunction are recognized as drivers of the development of non-AIDS related comorbidities (NARCs) in people living with HIV (PLHIV). In order to lower the risk of NARCs, it is critical to elucidate what is the contribution of alterations in the composition and function of circulating immune cells to NARCs-related pathogenesis. Findings from previous immunophenotyping studies in PLHIV are highly heterogeneous and it is not fully understood to what extent phenotypic changes on immune cells play a role in the dysregulated inflammatory response observed. Immunophenotyping Non-AIDS-related comorbidities (NARCs) HIV/AIDS Flow cytometry People living with HIV (PLHIV) Van de Wijer, Lisa verfasserin aut Jacobs-Cleophas, Maartje verfasserin aut Schimmel-Naber, A. Marlies verfasserin aut van Cranenbroek, Bram verfasserin aut van der Heijden, Wouter A. verfasserin aut van der Lei, Roelof J. verfasserin aut Vergara, Zaida verfasserin aut Netea, Mihai G. verfasserin aut van der Ven, André J.A.M. verfasserin aut Kapinsky, Michael verfasserin aut Koenen, Hans J.P.M. verfasserin aut Joosten, Leo A.B. verfasserin aut Enthalten in Journal of immunological methods Amsterdam [u.a.] : Elsevier Science, 1971 507 Online-Ressource (DE-627)306659751 (DE-600)1500495-8 (DE-576)081986386 1872-7905 nnns volume:507 GBV_USEFLAG_U SYSFLAG_U GBV_ELV SSG-OLC-PHA GBV_ILN_20 GBV_ILN_22 GBV_ILN_23 GBV_ILN_24 GBV_ILN_31 GBV_ILN_32 GBV_ILN_40 GBV_ILN_60 GBV_ILN_62 GBV_ILN_63 GBV_ILN_65 GBV_ILN_69 GBV_ILN_70 GBV_ILN_73 GBV_ILN_74 GBV_ILN_90 GBV_ILN_95 GBV_ILN_100 GBV_ILN_101 GBV_ILN_105 GBV_ILN_110 GBV_ILN_151 GBV_ILN_224 GBV_ILN_370 GBV_ILN_602 GBV_ILN_702 GBV_ILN_2003 GBV_ILN_2004 GBV_ILN_2005 GBV_ILN_2011 GBV_ILN_2014 GBV_ILN_2015 GBV_ILN_2020 GBV_ILN_2021 GBV_ILN_2025 GBV_ILN_2027 GBV_ILN_2034 GBV_ILN_2038 GBV_ILN_2044 GBV_ILN_2048 GBV_ILN_2049 GBV_ILN_2050 GBV_ILN_2056 GBV_ILN_2059 GBV_ILN_2061 GBV_ILN_2064 GBV_ILN_2065 GBV_ILN_2068 GBV_ILN_2111 GBV_ILN_2112 GBV_ILN_2113 GBV_ILN_2118 GBV_ILN_2122 GBV_ILN_2129 GBV_ILN_2143 GBV_ILN_2147 GBV_ILN_2148 GBV_ILN_2152 GBV_ILN_2153 GBV_ILN_2190 GBV_ILN_2336 GBV_ILN_2507 GBV_ILN_2522 GBV_ILN_4035 GBV_ILN_4037 GBV_ILN_4112 GBV_ILN_4125 GBV_ILN_4126 GBV_ILN_4242 GBV_ILN_4251 GBV_ILN_4305 GBV_ILN_4313 GBV_ILN_4323 GBV_ILN_4324 GBV_ILN_4325 GBV_ILN_4326 GBV_ILN_4333 GBV_ILN_4334 GBV_ILN_4335 GBV_ILN_4338 GBV_ILN_4393 44.45 Immunologie AR 507 |
allfields_unstemmed |
10.1016/j.jim.2022.113307 doi (DE-627)ELV008177597 (ELSEVIER)S0022-1759(22)00094-1 DE-627 ger DE-627 rda eng 610 DE-600 44.45 bkl Navas, Adriana verfasserin aut Comprehensive phenotyping of circulating immune cell subsets in people living with HIV 2022 nicht spezifiziert zzz rdacontent Computermedien c rdamedia Online-Ressource cr rdacarrier Systemic chronic inflammation and immune dysfunction are recognized as drivers of the development of non-AIDS related comorbidities (NARCs) in people living with HIV (PLHIV). In order to lower the risk of NARCs, it is critical to elucidate what is the contribution of alterations in the composition and function of circulating immune cells to NARCs-related pathogenesis. Findings from previous immunophenotyping studies in PLHIV are highly heterogeneous and it is not fully understood to what extent phenotypic changes on immune cells play a role in the dysregulated inflammatory response observed. Immunophenotyping Non-AIDS-related comorbidities (NARCs) HIV/AIDS Flow cytometry People living with HIV (PLHIV) Van de Wijer, Lisa verfasserin aut Jacobs-Cleophas, Maartje verfasserin aut Schimmel-Naber, A. Marlies verfasserin aut van Cranenbroek, Bram verfasserin aut van der Heijden, Wouter A. verfasserin aut van der Lei, Roelof J. verfasserin aut Vergara, Zaida verfasserin aut Netea, Mihai G. verfasserin aut van der Ven, André J.A.M. verfasserin aut Kapinsky, Michael verfasserin aut Koenen, Hans J.P.M. verfasserin aut Joosten, Leo A.B. verfasserin aut Enthalten in Journal of immunological methods Amsterdam [u.a.] : Elsevier Science, 1971 507 Online-Ressource (DE-627)306659751 (DE-600)1500495-8 (DE-576)081986386 1872-7905 nnns volume:507 GBV_USEFLAG_U SYSFLAG_U GBV_ELV SSG-OLC-PHA GBV_ILN_20 GBV_ILN_22 GBV_ILN_23 GBV_ILN_24 GBV_ILN_31 GBV_ILN_32 GBV_ILN_40 GBV_ILN_60 GBV_ILN_62 GBV_ILN_63 GBV_ILN_65 GBV_ILN_69 GBV_ILN_70 GBV_ILN_73 GBV_ILN_74 GBV_ILN_90 GBV_ILN_95 GBV_ILN_100 GBV_ILN_101 GBV_ILN_105 GBV_ILN_110 GBV_ILN_151 GBV_ILN_224 GBV_ILN_370 GBV_ILN_602 GBV_ILN_702 GBV_ILN_2003 GBV_ILN_2004 GBV_ILN_2005 GBV_ILN_2011 GBV_ILN_2014 GBV_ILN_2015 GBV_ILN_2020 GBV_ILN_2021 GBV_ILN_2025 GBV_ILN_2027 GBV_ILN_2034 GBV_ILN_2038 GBV_ILN_2044 GBV_ILN_2048 GBV_ILN_2049 GBV_ILN_2050 GBV_ILN_2056 GBV_ILN_2059 GBV_ILN_2061 GBV_ILN_2064 GBV_ILN_2065 GBV_ILN_2068 GBV_ILN_2111 GBV_ILN_2112 GBV_ILN_2113 GBV_ILN_2118 GBV_ILN_2122 GBV_ILN_2129 GBV_ILN_2143 GBV_ILN_2147 GBV_ILN_2148 GBV_ILN_2152 GBV_ILN_2153 GBV_ILN_2190 GBV_ILN_2336 GBV_ILN_2507 GBV_ILN_2522 GBV_ILN_4035 GBV_ILN_4037 GBV_ILN_4112 GBV_ILN_4125 GBV_ILN_4126 GBV_ILN_4242 GBV_ILN_4251 GBV_ILN_4305 GBV_ILN_4313 GBV_ILN_4323 GBV_ILN_4324 GBV_ILN_4325 GBV_ILN_4326 GBV_ILN_4333 GBV_ILN_4334 GBV_ILN_4335 GBV_ILN_4338 GBV_ILN_4393 44.45 Immunologie AR 507 |
allfieldsGer |
10.1016/j.jim.2022.113307 doi (DE-627)ELV008177597 (ELSEVIER)S0022-1759(22)00094-1 DE-627 ger DE-627 rda eng 610 DE-600 44.45 bkl Navas, Adriana verfasserin aut Comprehensive phenotyping of circulating immune cell subsets in people living with HIV 2022 nicht spezifiziert zzz rdacontent Computermedien c rdamedia Online-Ressource cr rdacarrier Systemic chronic inflammation and immune dysfunction are recognized as drivers of the development of non-AIDS related comorbidities (NARCs) in people living with HIV (PLHIV). In order to lower the risk of NARCs, it is critical to elucidate what is the contribution of alterations in the composition and function of circulating immune cells to NARCs-related pathogenesis. Findings from previous immunophenotyping studies in PLHIV are highly heterogeneous and it is not fully understood to what extent phenotypic changes on immune cells play a role in the dysregulated inflammatory response observed. Immunophenotyping Non-AIDS-related comorbidities (NARCs) HIV/AIDS Flow cytometry People living with HIV (PLHIV) Van de Wijer, Lisa verfasserin aut Jacobs-Cleophas, Maartje verfasserin aut Schimmel-Naber, A. Marlies verfasserin aut van Cranenbroek, Bram verfasserin aut van der Heijden, Wouter A. verfasserin aut van der Lei, Roelof J. verfasserin aut Vergara, Zaida verfasserin aut Netea, Mihai G. verfasserin aut van der Ven, André J.A.M. verfasserin aut Kapinsky, Michael verfasserin aut Koenen, Hans J.P.M. verfasserin aut Joosten, Leo A.B. verfasserin aut Enthalten in Journal of immunological methods Amsterdam [u.a.] : Elsevier Science, 1971 507 Online-Ressource (DE-627)306659751 (DE-600)1500495-8 (DE-576)081986386 1872-7905 nnns volume:507 GBV_USEFLAG_U SYSFLAG_U GBV_ELV SSG-OLC-PHA GBV_ILN_20 GBV_ILN_22 GBV_ILN_23 GBV_ILN_24 GBV_ILN_31 GBV_ILN_32 GBV_ILN_40 GBV_ILN_60 GBV_ILN_62 GBV_ILN_63 GBV_ILN_65 GBV_ILN_69 GBV_ILN_70 GBV_ILN_73 GBV_ILN_74 GBV_ILN_90 GBV_ILN_95 GBV_ILN_100 GBV_ILN_101 GBV_ILN_105 GBV_ILN_110 GBV_ILN_151 GBV_ILN_224 GBV_ILN_370 GBV_ILN_602 GBV_ILN_702 GBV_ILN_2003 GBV_ILN_2004 GBV_ILN_2005 GBV_ILN_2011 GBV_ILN_2014 GBV_ILN_2015 GBV_ILN_2020 GBV_ILN_2021 GBV_ILN_2025 GBV_ILN_2027 GBV_ILN_2034 GBV_ILN_2038 GBV_ILN_2044 GBV_ILN_2048 GBV_ILN_2049 GBV_ILN_2050 GBV_ILN_2056 GBV_ILN_2059 GBV_ILN_2061 GBV_ILN_2064 GBV_ILN_2065 GBV_ILN_2068 GBV_ILN_2111 GBV_ILN_2112 GBV_ILN_2113 GBV_ILN_2118 GBV_ILN_2122 GBV_ILN_2129 GBV_ILN_2143 GBV_ILN_2147 GBV_ILN_2148 GBV_ILN_2152 GBV_ILN_2153 GBV_ILN_2190 GBV_ILN_2336 GBV_ILN_2507 GBV_ILN_2522 GBV_ILN_4035 GBV_ILN_4037 GBV_ILN_4112 GBV_ILN_4125 GBV_ILN_4126 GBV_ILN_4242 GBV_ILN_4251 GBV_ILN_4305 GBV_ILN_4313 GBV_ILN_4323 GBV_ILN_4324 GBV_ILN_4325 GBV_ILN_4326 GBV_ILN_4333 GBV_ILN_4334 GBV_ILN_4335 GBV_ILN_4338 GBV_ILN_4393 44.45 Immunologie AR 507 |
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10.1016/j.jim.2022.113307 doi (DE-627)ELV008177597 (ELSEVIER)S0022-1759(22)00094-1 DE-627 ger DE-627 rda eng 610 DE-600 44.45 bkl Navas, Adriana verfasserin aut Comprehensive phenotyping of circulating immune cell subsets in people living with HIV 2022 nicht spezifiziert zzz rdacontent Computermedien c rdamedia Online-Ressource cr rdacarrier Systemic chronic inflammation and immune dysfunction are recognized as drivers of the development of non-AIDS related comorbidities (NARCs) in people living with HIV (PLHIV). In order to lower the risk of NARCs, it is critical to elucidate what is the contribution of alterations in the composition and function of circulating immune cells to NARCs-related pathogenesis. Findings from previous immunophenotyping studies in PLHIV are highly heterogeneous and it is not fully understood to what extent phenotypic changes on immune cells play a role in the dysregulated inflammatory response observed. Immunophenotyping Non-AIDS-related comorbidities (NARCs) HIV/AIDS Flow cytometry People living with HIV (PLHIV) Van de Wijer, Lisa verfasserin aut Jacobs-Cleophas, Maartje verfasserin aut Schimmel-Naber, A. Marlies verfasserin aut van Cranenbroek, Bram verfasserin aut van der Heijden, Wouter A. verfasserin aut van der Lei, Roelof J. verfasserin aut Vergara, Zaida verfasserin aut Netea, Mihai G. verfasserin aut van der Ven, André J.A.M. verfasserin aut Kapinsky, Michael verfasserin aut Koenen, Hans J.P.M. verfasserin aut Joosten, Leo A.B. verfasserin aut Enthalten in Journal of immunological methods Amsterdam [u.a.] : Elsevier Science, 1971 507 Online-Ressource (DE-627)306659751 (DE-600)1500495-8 (DE-576)081986386 1872-7905 nnns volume:507 GBV_USEFLAG_U SYSFLAG_U GBV_ELV SSG-OLC-PHA GBV_ILN_20 GBV_ILN_22 GBV_ILN_23 GBV_ILN_24 GBV_ILN_31 GBV_ILN_32 GBV_ILN_40 GBV_ILN_60 GBV_ILN_62 GBV_ILN_63 GBV_ILN_65 GBV_ILN_69 GBV_ILN_70 GBV_ILN_73 GBV_ILN_74 GBV_ILN_90 GBV_ILN_95 GBV_ILN_100 GBV_ILN_101 GBV_ILN_105 GBV_ILN_110 GBV_ILN_151 GBV_ILN_224 GBV_ILN_370 GBV_ILN_602 GBV_ILN_702 GBV_ILN_2003 GBV_ILN_2004 GBV_ILN_2005 GBV_ILN_2011 GBV_ILN_2014 GBV_ILN_2015 GBV_ILN_2020 GBV_ILN_2021 GBV_ILN_2025 GBV_ILN_2027 GBV_ILN_2034 GBV_ILN_2038 GBV_ILN_2044 GBV_ILN_2048 GBV_ILN_2049 GBV_ILN_2050 GBV_ILN_2056 GBV_ILN_2059 GBV_ILN_2061 GBV_ILN_2064 GBV_ILN_2065 GBV_ILN_2068 GBV_ILN_2111 GBV_ILN_2112 GBV_ILN_2113 GBV_ILN_2118 GBV_ILN_2122 GBV_ILN_2129 GBV_ILN_2143 GBV_ILN_2147 GBV_ILN_2148 GBV_ILN_2152 GBV_ILN_2153 GBV_ILN_2190 GBV_ILN_2336 GBV_ILN_2507 GBV_ILN_2522 GBV_ILN_4035 GBV_ILN_4037 GBV_ILN_4112 GBV_ILN_4125 GBV_ILN_4126 GBV_ILN_4242 GBV_ILN_4251 GBV_ILN_4305 GBV_ILN_4313 GBV_ILN_4323 GBV_ILN_4324 GBV_ILN_4325 GBV_ILN_4326 GBV_ILN_4333 GBV_ILN_4334 GBV_ILN_4335 GBV_ILN_4338 GBV_ILN_4393 44.45 Immunologie AR 507 |
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610 DE-600 44.45 bkl Comprehensive phenotyping of circulating immune cell subsets in people living with HIV Immunophenotyping Non-AIDS-related comorbidities (NARCs) HIV/AIDS Flow cytometry People living with HIV (PLHIV) |
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ddc 610 bkl 44.45 misc Immunophenotyping misc Non-AIDS-related comorbidities (NARCs) misc HIV/AIDS misc Flow cytometry misc People living with HIV (PLHIV) |
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Comprehensive phenotyping of circulating immune cell subsets in people living with HIV |
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Comprehensive phenotyping of circulating immune cell subsets in people living with HIV |
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Navas, Adriana |
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Navas, Adriana Van de Wijer, Lisa Jacobs-Cleophas, Maartje Schimmel-Naber, A. Marlies van Cranenbroek, Bram van der Heijden, Wouter A. van der Lei, Roelof J. Vergara, Zaida Netea, Mihai G. van der Ven, André J.A.M. Kapinsky, Michael Koenen, Hans J.P.M. Joosten, Leo A.B. |
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comprehensive phenotyping of circulating immune cell subsets in people living with hiv |
title_auth |
Comprehensive phenotyping of circulating immune cell subsets in people living with HIV |
abstract |
Systemic chronic inflammation and immune dysfunction are recognized as drivers of the development of non-AIDS related comorbidities (NARCs) in people living with HIV (PLHIV). In order to lower the risk of NARCs, it is critical to elucidate what is the contribution of alterations in the composition and function of circulating immune cells to NARCs-related pathogenesis. Findings from previous immunophenotyping studies in PLHIV are highly heterogeneous and it is not fully understood to what extent phenotypic changes on immune cells play a role in the dysregulated inflammatory response observed. |
abstractGer |
Systemic chronic inflammation and immune dysfunction are recognized as drivers of the development of non-AIDS related comorbidities (NARCs) in people living with HIV (PLHIV). In order to lower the risk of NARCs, it is critical to elucidate what is the contribution of alterations in the composition and function of circulating immune cells to NARCs-related pathogenesis. Findings from previous immunophenotyping studies in PLHIV are highly heterogeneous and it is not fully understood to what extent phenotypic changes on immune cells play a role in the dysregulated inflammatory response observed. |
abstract_unstemmed |
Systemic chronic inflammation and immune dysfunction are recognized as drivers of the development of non-AIDS related comorbidities (NARCs) in people living with HIV (PLHIV). In order to lower the risk of NARCs, it is critical to elucidate what is the contribution of alterations in the composition and function of circulating immune cells to NARCs-related pathogenesis. Findings from previous immunophenotyping studies in PLHIV are highly heterogeneous and it is not fully understood to what extent phenotypic changes on immune cells play a role in the dysregulated inflammatory response observed. |
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Comprehensive phenotyping of circulating immune cell subsets in people living with HIV |
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Van de Wijer, Lisa Jacobs-Cleophas, Maartje Schimmel-Naber, A. Marlies van Cranenbroek, Bram van der Heijden, Wouter A. van der Lei, Roelof J. Vergara, Zaida Netea, Mihai G. van der Ven, André J.A.M. Kapinsky, Michael Koenen, Hans J.P.M. Joosten, Leo A.B. |
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