Structural characterization and protective effect on PC12 cells against H 2 O 2 -induced oxidative damage of a polysaccharide from Isaria cicadae Miquel mycelium and its zinc derivative
A homogeneous polysaccharide, ICMP-1, was isolated from the cultured mycelia of Isaria cicadae Miquel by hot water extraction. ICMP-1 (3.87 ×103 kDa) was a heteropolysaccharide mainly consisting of T-α-D-Glcp, →4)-α-D-Glcp-(1→, →4,6)-α-D-Manp-(1→, and →4)-β-D-Galp-(1→. In order to improve the antiox...
Ausführliche Beschreibung
Autor*in: |
Wang, Siqiang [verfasserIn] Yang, Ximei [verfasserIn] Hou, Xuening [verfasserIn] Zhu, Zhenyuan [verfasserIn] |
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Format: |
E-Artikel |
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Sprache: |
Englisch |
Erschienen: |
2022 |
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Schlagwörter: |
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Übergeordnetes Werk: |
Enthalten in: Process biochemistry - Amsterdam [u.a.] : Elsevier Science, 1991, 122 |
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Übergeordnetes Werk: |
volume:122 |
DOI / URN: |
10.1016/j.procbio.2022.10.022 |
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Katalog-ID: |
ELV008740232 |
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245 | 1 | 0 | |a Structural characterization and protective effect on PC12 cells against H 2 O 2 -induced oxidative damage of a polysaccharide from Isaria cicadae Miquel mycelium and its zinc derivative |
264 | 1 | |c 2022 | |
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520 | |a A homogeneous polysaccharide, ICMP-1, was isolated from the cultured mycelia of Isaria cicadae Miquel by hot water extraction. ICMP-1 (3.87 ×103 kDa) was a heteropolysaccharide mainly consisting of T-α-D-Glcp, →4)-α-D-Glcp-(1→, →4,6)-α-D-Manp-(1→, and →4)-β-D-Galp-(1→. In order to improve the antioxidant activity and the potential applications of ICMP-1, a typical ZnCl2 modification on ICMP-1 was carried out. Fourier-transform infrared spectroscopy (FT-IR), Energy dispersive spectrometer (EDS), scanning electron microscopy (SEM), atomic force microscope (AFM) and X-ray photoelectron spectroscopy (XPS) analysis confirmed that Zn was successfully introduced into the polymer chain of ICMP-1. The zinc modification derivative (ICMP-1-Zn) can alleviate H2O2-induced oxidative damage on PC12 cells. The stronger antioxidant activity of ICMP-1-Zn may be achieved by promoting the activity of zinc-containing enzymes, such as superoxide dismutase and lactate dehydrogenase. | ||
650 | 4 | |a Polysaccharides | |
650 | 4 | |a Polysaccharide-Zn complex | |
650 | 4 | |a Structural characterization | |
650 | 4 | |a Oxidative stress | |
700 | 1 | |a Yang, Ximei |e verfasserin |4 aut | |
700 | 1 | |a Hou, Xuening |e verfasserin |4 aut | |
700 | 1 | |a Zhu, Zhenyuan |e verfasserin |4 aut | |
773 | 0 | 8 | |i Enthalten in |t Process biochemistry |d Amsterdam [u.a.] : Elsevier Science, 1991 |g 122 |h Online-Ressource |w (DE-627)320570916 |w (DE-600)2016483-X |w (DE-576)259484989 |x 0032-9592 |7 nnns |
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912 | |a GBV_ILN_90 | ||
912 | |a GBV_ILN_95 | ||
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912 | |a GBV_ILN_101 | ||
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912 | |a GBV_ILN_110 | ||
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912 | |a GBV_ILN_151 | ||
912 | |a GBV_ILN_224 | ||
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912 | |a GBV_ILN_2034 | ||
912 | |a GBV_ILN_2038 | ||
912 | |a GBV_ILN_2044 | ||
912 | |a GBV_ILN_2048 | ||
912 | |a GBV_ILN_2049 | ||
912 | |a GBV_ILN_2050 | ||
912 | |a GBV_ILN_2056 | ||
912 | |a GBV_ILN_2059 | ||
912 | |a GBV_ILN_2061 | ||
912 | |a GBV_ILN_2064 | ||
912 | |a GBV_ILN_2065 | ||
912 | |a GBV_ILN_2068 | ||
912 | |a GBV_ILN_2111 | ||
912 | |a GBV_ILN_2112 | ||
912 | |a GBV_ILN_2113 | ||
912 | |a GBV_ILN_2118 | ||
912 | |a GBV_ILN_2122 | ||
912 | |a GBV_ILN_2129 | ||
912 | |a GBV_ILN_2143 | ||
912 | |a GBV_ILN_2147 | ||
912 | |a GBV_ILN_2148 | ||
912 | |a GBV_ILN_2152 | ||
912 | |a GBV_ILN_2153 | ||
912 | |a GBV_ILN_2190 | ||
912 | |a GBV_ILN_2336 | ||
912 | |a GBV_ILN_2507 | ||
912 | |a GBV_ILN_2522 | ||
912 | |a GBV_ILN_4035 | ||
912 | |a GBV_ILN_4037 | ||
912 | |a GBV_ILN_4112 | ||
912 | |a GBV_ILN_4125 | ||
912 | |a GBV_ILN_4126 | ||
912 | |a GBV_ILN_4242 | ||
912 | |a GBV_ILN_4251 | ||
912 | |a GBV_ILN_4305 | ||
912 | |a GBV_ILN_4313 | ||
912 | |a GBV_ILN_4323 | ||
912 | |a GBV_ILN_4324 | ||
912 | |a GBV_ILN_4326 | ||
912 | |a GBV_ILN_4333 | ||
912 | |a GBV_ILN_4334 | ||
912 | |a GBV_ILN_4335 | ||
912 | |a GBV_ILN_4338 | ||
912 | |a GBV_ILN_4393 | ||
936 | b | k | |a 42.30 |j Mikrobiologie |q VZ |
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2022 |
allfields |
10.1016/j.procbio.2022.10.022 doi (DE-627)ELV008740232 (ELSEVIER)S1359-5113(22)00379-8 DE-627 ger DE-627 rda eng 530 VZ 42.30 bkl 58.30 bkl 58.34 bkl Wang, Siqiang verfasserin aut Structural characterization and protective effect on PC12 cells against H 2 O 2 -induced oxidative damage of a polysaccharide from Isaria cicadae Miquel mycelium and its zinc derivative 2022 nicht spezifiziert zzz rdacontent Computermedien c rdamedia Online-Ressource cr rdacarrier A homogeneous polysaccharide, ICMP-1, was isolated from the cultured mycelia of Isaria cicadae Miquel by hot water extraction. ICMP-1 (3.87 ×103 kDa) was a heteropolysaccharide mainly consisting of T-α-D-Glcp, →4)-α-D-Glcp-(1→, →4,6)-α-D-Manp-(1→, and →4)-β-D-Galp-(1→. In order to improve the antioxidant activity and the potential applications of ICMP-1, a typical ZnCl2 modification on ICMP-1 was carried out. Fourier-transform infrared spectroscopy (FT-IR), Energy dispersive spectrometer (EDS), scanning electron microscopy (SEM), atomic force microscope (AFM) and X-ray photoelectron spectroscopy (XPS) analysis confirmed that Zn was successfully introduced into the polymer chain of ICMP-1. The zinc modification derivative (ICMP-1-Zn) can alleviate H2O2-induced oxidative damage on PC12 cells. The stronger antioxidant activity of ICMP-1-Zn may be achieved by promoting the activity of zinc-containing enzymes, such as superoxide dismutase and lactate dehydrogenase. Polysaccharides Polysaccharide-Zn complex Structural characterization Oxidative stress Yang, Ximei verfasserin aut Hou, Xuening verfasserin aut Zhu, Zhenyuan verfasserin aut Enthalten in Process biochemistry Amsterdam [u.a.] : Elsevier Science, 1991 122 Online-Ressource (DE-627)320570916 (DE-600)2016483-X (DE-576)259484989 0032-9592 nnns volume:122 GBV_USEFLAG_U GBV_ELV SYSFLAG_U GBV_ILN_20 GBV_ILN_22 GBV_ILN_23 GBV_ILN_24 GBV_ILN_31 GBV_ILN_32 GBV_ILN_40 GBV_ILN_60 GBV_ILN_62 GBV_ILN_63 GBV_ILN_65 GBV_ILN_69 GBV_ILN_70 GBV_ILN_73 GBV_ILN_74 GBV_ILN_90 GBV_ILN_95 GBV_ILN_100 GBV_ILN_101 GBV_ILN_105 GBV_ILN_110 GBV_ILN_150 GBV_ILN_151 GBV_ILN_224 GBV_ILN_370 GBV_ILN_602 GBV_ILN_702 GBV_ILN_2003 GBV_ILN_2004 GBV_ILN_2005 GBV_ILN_2011 GBV_ILN_2014 GBV_ILN_2015 GBV_ILN_2020 GBV_ILN_2021 GBV_ILN_2025 GBV_ILN_2027 GBV_ILN_2034 GBV_ILN_2038 GBV_ILN_2044 GBV_ILN_2048 GBV_ILN_2049 GBV_ILN_2050 GBV_ILN_2056 GBV_ILN_2059 GBV_ILN_2061 GBV_ILN_2064 GBV_ILN_2065 GBV_ILN_2068 GBV_ILN_2111 GBV_ILN_2112 GBV_ILN_2113 GBV_ILN_2118 GBV_ILN_2122 GBV_ILN_2129 GBV_ILN_2143 GBV_ILN_2147 GBV_ILN_2148 GBV_ILN_2152 GBV_ILN_2153 GBV_ILN_2190 GBV_ILN_2336 GBV_ILN_2507 GBV_ILN_2522 GBV_ILN_4035 GBV_ILN_4037 GBV_ILN_4112 GBV_ILN_4125 GBV_ILN_4126 GBV_ILN_4242 GBV_ILN_4251 GBV_ILN_4305 GBV_ILN_4313 GBV_ILN_4323 GBV_ILN_4324 GBV_ILN_4326 GBV_ILN_4333 GBV_ILN_4334 GBV_ILN_4335 GBV_ILN_4338 GBV_ILN_4393 42.30 Mikrobiologie VZ 58.30 Biotechnologie VZ 58.34 Lebensmitteltechnologie VZ AR 122 |
spelling |
10.1016/j.procbio.2022.10.022 doi (DE-627)ELV008740232 (ELSEVIER)S1359-5113(22)00379-8 DE-627 ger DE-627 rda eng 530 VZ 42.30 bkl 58.30 bkl 58.34 bkl Wang, Siqiang verfasserin aut Structural characterization and protective effect on PC12 cells against H 2 O 2 -induced oxidative damage of a polysaccharide from Isaria cicadae Miquel mycelium and its zinc derivative 2022 nicht spezifiziert zzz rdacontent Computermedien c rdamedia Online-Ressource cr rdacarrier A homogeneous polysaccharide, ICMP-1, was isolated from the cultured mycelia of Isaria cicadae Miquel by hot water extraction. ICMP-1 (3.87 ×103 kDa) was a heteropolysaccharide mainly consisting of T-α-D-Glcp, →4)-α-D-Glcp-(1→, →4,6)-α-D-Manp-(1→, and →4)-β-D-Galp-(1→. In order to improve the antioxidant activity and the potential applications of ICMP-1, a typical ZnCl2 modification on ICMP-1 was carried out. Fourier-transform infrared spectroscopy (FT-IR), Energy dispersive spectrometer (EDS), scanning electron microscopy (SEM), atomic force microscope (AFM) and X-ray photoelectron spectroscopy (XPS) analysis confirmed that Zn was successfully introduced into the polymer chain of ICMP-1. The zinc modification derivative (ICMP-1-Zn) can alleviate H2O2-induced oxidative damage on PC12 cells. The stronger antioxidant activity of ICMP-1-Zn may be achieved by promoting the activity of zinc-containing enzymes, such as superoxide dismutase and lactate dehydrogenase. Polysaccharides Polysaccharide-Zn complex Structural characterization Oxidative stress Yang, Ximei verfasserin aut Hou, Xuening verfasserin aut Zhu, Zhenyuan verfasserin aut Enthalten in Process biochemistry Amsterdam [u.a.] : Elsevier Science, 1991 122 Online-Ressource (DE-627)320570916 (DE-600)2016483-X (DE-576)259484989 0032-9592 nnns volume:122 GBV_USEFLAG_U GBV_ELV SYSFLAG_U GBV_ILN_20 GBV_ILN_22 GBV_ILN_23 GBV_ILN_24 GBV_ILN_31 GBV_ILN_32 GBV_ILN_40 GBV_ILN_60 GBV_ILN_62 GBV_ILN_63 GBV_ILN_65 GBV_ILN_69 GBV_ILN_70 GBV_ILN_73 GBV_ILN_74 GBV_ILN_90 GBV_ILN_95 GBV_ILN_100 GBV_ILN_101 GBV_ILN_105 GBV_ILN_110 GBV_ILN_150 GBV_ILN_151 GBV_ILN_224 GBV_ILN_370 GBV_ILN_602 GBV_ILN_702 GBV_ILN_2003 GBV_ILN_2004 GBV_ILN_2005 GBV_ILN_2011 GBV_ILN_2014 GBV_ILN_2015 GBV_ILN_2020 GBV_ILN_2021 GBV_ILN_2025 GBV_ILN_2027 GBV_ILN_2034 GBV_ILN_2038 GBV_ILN_2044 GBV_ILN_2048 GBV_ILN_2049 GBV_ILN_2050 GBV_ILN_2056 GBV_ILN_2059 GBV_ILN_2061 GBV_ILN_2064 GBV_ILN_2065 GBV_ILN_2068 GBV_ILN_2111 GBV_ILN_2112 GBV_ILN_2113 GBV_ILN_2118 GBV_ILN_2122 GBV_ILN_2129 GBV_ILN_2143 GBV_ILN_2147 GBV_ILN_2148 GBV_ILN_2152 GBV_ILN_2153 GBV_ILN_2190 GBV_ILN_2336 GBV_ILN_2507 GBV_ILN_2522 GBV_ILN_4035 GBV_ILN_4037 GBV_ILN_4112 GBV_ILN_4125 GBV_ILN_4126 GBV_ILN_4242 GBV_ILN_4251 GBV_ILN_4305 GBV_ILN_4313 GBV_ILN_4323 GBV_ILN_4324 GBV_ILN_4326 GBV_ILN_4333 GBV_ILN_4334 GBV_ILN_4335 GBV_ILN_4338 GBV_ILN_4393 42.30 Mikrobiologie VZ 58.30 Biotechnologie VZ 58.34 Lebensmitteltechnologie VZ AR 122 |
allfields_unstemmed |
10.1016/j.procbio.2022.10.022 doi (DE-627)ELV008740232 (ELSEVIER)S1359-5113(22)00379-8 DE-627 ger DE-627 rda eng 530 VZ 42.30 bkl 58.30 bkl 58.34 bkl Wang, Siqiang verfasserin aut Structural characterization and protective effect on PC12 cells against H 2 O 2 -induced oxidative damage of a polysaccharide from Isaria cicadae Miquel mycelium and its zinc derivative 2022 nicht spezifiziert zzz rdacontent Computermedien c rdamedia Online-Ressource cr rdacarrier A homogeneous polysaccharide, ICMP-1, was isolated from the cultured mycelia of Isaria cicadae Miquel by hot water extraction. ICMP-1 (3.87 ×103 kDa) was a heteropolysaccharide mainly consisting of T-α-D-Glcp, →4)-α-D-Glcp-(1→, →4,6)-α-D-Manp-(1→, and →4)-β-D-Galp-(1→. In order to improve the antioxidant activity and the potential applications of ICMP-1, a typical ZnCl2 modification on ICMP-1 was carried out. Fourier-transform infrared spectroscopy (FT-IR), Energy dispersive spectrometer (EDS), scanning electron microscopy (SEM), atomic force microscope (AFM) and X-ray photoelectron spectroscopy (XPS) analysis confirmed that Zn was successfully introduced into the polymer chain of ICMP-1. The zinc modification derivative (ICMP-1-Zn) can alleviate H2O2-induced oxidative damage on PC12 cells. The stronger antioxidant activity of ICMP-1-Zn may be achieved by promoting the activity of zinc-containing enzymes, such as superoxide dismutase and lactate dehydrogenase. Polysaccharides Polysaccharide-Zn complex Structural characterization Oxidative stress Yang, Ximei verfasserin aut Hou, Xuening verfasserin aut Zhu, Zhenyuan verfasserin aut Enthalten in Process biochemistry Amsterdam [u.a.] : Elsevier Science, 1991 122 Online-Ressource (DE-627)320570916 (DE-600)2016483-X (DE-576)259484989 0032-9592 nnns volume:122 GBV_USEFLAG_U GBV_ELV SYSFLAG_U GBV_ILN_20 GBV_ILN_22 GBV_ILN_23 GBV_ILN_24 GBV_ILN_31 GBV_ILN_32 GBV_ILN_40 GBV_ILN_60 GBV_ILN_62 GBV_ILN_63 GBV_ILN_65 GBV_ILN_69 GBV_ILN_70 GBV_ILN_73 GBV_ILN_74 GBV_ILN_90 GBV_ILN_95 GBV_ILN_100 GBV_ILN_101 GBV_ILN_105 GBV_ILN_110 GBV_ILN_150 GBV_ILN_151 GBV_ILN_224 GBV_ILN_370 GBV_ILN_602 GBV_ILN_702 GBV_ILN_2003 GBV_ILN_2004 GBV_ILN_2005 GBV_ILN_2011 GBV_ILN_2014 GBV_ILN_2015 GBV_ILN_2020 GBV_ILN_2021 GBV_ILN_2025 GBV_ILN_2027 GBV_ILN_2034 GBV_ILN_2038 GBV_ILN_2044 GBV_ILN_2048 GBV_ILN_2049 GBV_ILN_2050 GBV_ILN_2056 GBV_ILN_2059 GBV_ILN_2061 GBV_ILN_2064 GBV_ILN_2065 GBV_ILN_2068 GBV_ILN_2111 GBV_ILN_2112 GBV_ILN_2113 GBV_ILN_2118 GBV_ILN_2122 GBV_ILN_2129 GBV_ILN_2143 GBV_ILN_2147 GBV_ILN_2148 GBV_ILN_2152 GBV_ILN_2153 GBV_ILN_2190 GBV_ILN_2336 GBV_ILN_2507 GBV_ILN_2522 GBV_ILN_4035 GBV_ILN_4037 GBV_ILN_4112 GBV_ILN_4125 GBV_ILN_4126 GBV_ILN_4242 GBV_ILN_4251 GBV_ILN_4305 GBV_ILN_4313 GBV_ILN_4323 GBV_ILN_4324 GBV_ILN_4326 GBV_ILN_4333 GBV_ILN_4334 GBV_ILN_4335 GBV_ILN_4338 GBV_ILN_4393 42.30 Mikrobiologie VZ 58.30 Biotechnologie VZ 58.34 Lebensmitteltechnologie VZ AR 122 |
allfieldsGer |
10.1016/j.procbio.2022.10.022 doi (DE-627)ELV008740232 (ELSEVIER)S1359-5113(22)00379-8 DE-627 ger DE-627 rda eng 530 VZ 42.30 bkl 58.30 bkl 58.34 bkl Wang, Siqiang verfasserin aut Structural characterization and protective effect on PC12 cells against H 2 O 2 -induced oxidative damage of a polysaccharide from Isaria cicadae Miquel mycelium and its zinc derivative 2022 nicht spezifiziert zzz rdacontent Computermedien c rdamedia Online-Ressource cr rdacarrier A homogeneous polysaccharide, ICMP-1, was isolated from the cultured mycelia of Isaria cicadae Miquel by hot water extraction. ICMP-1 (3.87 ×103 kDa) was a heteropolysaccharide mainly consisting of T-α-D-Glcp, →4)-α-D-Glcp-(1→, →4,6)-α-D-Manp-(1→, and →4)-β-D-Galp-(1→. In order to improve the antioxidant activity and the potential applications of ICMP-1, a typical ZnCl2 modification on ICMP-1 was carried out. Fourier-transform infrared spectroscopy (FT-IR), Energy dispersive spectrometer (EDS), scanning electron microscopy (SEM), atomic force microscope (AFM) and X-ray photoelectron spectroscopy (XPS) analysis confirmed that Zn was successfully introduced into the polymer chain of ICMP-1. The zinc modification derivative (ICMP-1-Zn) can alleviate H2O2-induced oxidative damage on PC12 cells. The stronger antioxidant activity of ICMP-1-Zn may be achieved by promoting the activity of zinc-containing enzymes, such as superoxide dismutase and lactate dehydrogenase. Polysaccharides Polysaccharide-Zn complex Structural characterization Oxidative stress Yang, Ximei verfasserin aut Hou, Xuening verfasserin aut Zhu, Zhenyuan verfasserin aut Enthalten in Process biochemistry Amsterdam [u.a.] : Elsevier Science, 1991 122 Online-Ressource (DE-627)320570916 (DE-600)2016483-X (DE-576)259484989 0032-9592 nnns volume:122 GBV_USEFLAG_U GBV_ELV SYSFLAG_U GBV_ILN_20 GBV_ILN_22 GBV_ILN_23 GBV_ILN_24 GBV_ILN_31 GBV_ILN_32 GBV_ILN_40 GBV_ILN_60 GBV_ILN_62 GBV_ILN_63 GBV_ILN_65 GBV_ILN_69 GBV_ILN_70 GBV_ILN_73 GBV_ILN_74 GBV_ILN_90 GBV_ILN_95 GBV_ILN_100 GBV_ILN_101 GBV_ILN_105 GBV_ILN_110 GBV_ILN_150 GBV_ILN_151 GBV_ILN_224 GBV_ILN_370 GBV_ILN_602 GBV_ILN_702 GBV_ILN_2003 GBV_ILN_2004 GBV_ILN_2005 GBV_ILN_2011 GBV_ILN_2014 GBV_ILN_2015 GBV_ILN_2020 GBV_ILN_2021 GBV_ILN_2025 GBV_ILN_2027 GBV_ILN_2034 GBV_ILN_2038 GBV_ILN_2044 GBV_ILN_2048 GBV_ILN_2049 GBV_ILN_2050 GBV_ILN_2056 GBV_ILN_2059 GBV_ILN_2061 GBV_ILN_2064 GBV_ILN_2065 GBV_ILN_2068 GBV_ILN_2111 GBV_ILN_2112 GBV_ILN_2113 GBV_ILN_2118 GBV_ILN_2122 GBV_ILN_2129 GBV_ILN_2143 GBV_ILN_2147 GBV_ILN_2148 GBV_ILN_2152 GBV_ILN_2153 GBV_ILN_2190 GBV_ILN_2336 GBV_ILN_2507 GBV_ILN_2522 GBV_ILN_4035 GBV_ILN_4037 GBV_ILN_4112 GBV_ILN_4125 GBV_ILN_4126 GBV_ILN_4242 GBV_ILN_4251 GBV_ILN_4305 GBV_ILN_4313 GBV_ILN_4323 GBV_ILN_4324 GBV_ILN_4326 GBV_ILN_4333 GBV_ILN_4334 GBV_ILN_4335 GBV_ILN_4338 GBV_ILN_4393 42.30 Mikrobiologie VZ 58.30 Biotechnologie VZ 58.34 Lebensmitteltechnologie VZ AR 122 |
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10.1016/j.procbio.2022.10.022 doi (DE-627)ELV008740232 (ELSEVIER)S1359-5113(22)00379-8 DE-627 ger DE-627 rda eng 530 VZ 42.30 bkl 58.30 bkl 58.34 bkl Wang, Siqiang verfasserin aut Structural characterization and protective effect on PC12 cells against H 2 O 2 -induced oxidative damage of a polysaccharide from Isaria cicadae Miquel mycelium and its zinc derivative 2022 nicht spezifiziert zzz rdacontent Computermedien c rdamedia Online-Ressource cr rdacarrier A homogeneous polysaccharide, ICMP-1, was isolated from the cultured mycelia of Isaria cicadae Miquel by hot water extraction. ICMP-1 (3.87 ×103 kDa) was a heteropolysaccharide mainly consisting of T-α-D-Glcp, →4)-α-D-Glcp-(1→, →4,6)-α-D-Manp-(1→, and →4)-β-D-Galp-(1→. In order to improve the antioxidant activity and the potential applications of ICMP-1, a typical ZnCl2 modification on ICMP-1 was carried out. Fourier-transform infrared spectroscopy (FT-IR), Energy dispersive spectrometer (EDS), scanning electron microscopy (SEM), atomic force microscope (AFM) and X-ray photoelectron spectroscopy (XPS) analysis confirmed that Zn was successfully introduced into the polymer chain of ICMP-1. The zinc modification derivative (ICMP-1-Zn) can alleviate H2O2-induced oxidative damage on PC12 cells. The stronger antioxidant activity of ICMP-1-Zn may be achieved by promoting the activity of zinc-containing enzymes, such as superoxide dismutase and lactate dehydrogenase. Polysaccharides Polysaccharide-Zn complex Structural characterization Oxidative stress Yang, Ximei verfasserin aut Hou, Xuening verfasserin aut Zhu, Zhenyuan verfasserin aut Enthalten in Process biochemistry Amsterdam [u.a.] : Elsevier Science, 1991 122 Online-Ressource (DE-627)320570916 (DE-600)2016483-X (DE-576)259484989 0032-9592 nnns volume:122 GBV_USEFLAG_U GBV_ELV SYSFLAG_U GBV_ILN_20 GBV_ILN_22 GBV_ILN_23 GBV_ILN_24 GBV_ILN_31 GBV_ILN_32 GBV_ILN_40 GBV_ILN_60 GBV_ILN_62 GBV_ILN_63 GBV_ILN_65 GBV_ILN_69 GBV_ILN_70 GBV_ILN_73 GBV_ILN_74 GBV_ILN_90 GBV_ILN_95 GBV_ILN_100 GBV_ILN_101 GBV_ILN_105 GBV_ILN_110 GBV_ILN_150 GBV_ILN_151 GBV_ILN_224 GBV_ILN_370 GBV_ILN_602 GBV_ILN_702 GBV_ILN_2003 GBV_ILN_2004 GBV_ILN_2005 GBV_ILN_2011 GBV_ILN_2014 GBV_ILN_2015 GBV_ILN_2020 GBV_ILN_2021 GBV_ILN_2025 GBV_ILN_2027 GBV_ILN_2034 GBV_ILN_2038 GBV_ILN_2044 GBV_ILN_2048 GBV_ILN_2049 GBV_ILN_2050 GBV_ILN_2056 GBV_ILN_2059 GBV_ILN_2061 GBV_ILN_2064 GBV_ILN_2065 GBV_ILN_2068 GBV_ILN_2111 GBV_ILN_2112 GBV_ILN_2113 GBV_ILN_2118 GBV_ILN_2122 GBV_ILN_2129 GBV_ILN_2143 GBV_ILN_2147 GBV_ILN_2148 GBV_ILN_2152 GBV_ILN_2153 GBV_ILN_2190 GBV_ILN_2336 GBV_ILN_2507 GBV_ILN_2522 GBV_ILN_4035 GBV_ILN_4037 GBV_ILN_4112 GBV_ILN_4125 GBV_ILN_4126 GBV_ILN_4242 GBV_ILN_4251 GBV_ILN_4305 GBV_ILN_4313 GBV_ILN_4323 GBV_ILN_4324 GBV_ILN_4326 GBV_ILN_4333 GBV_ILN_4334 GBV_ILN_4335 GBV_ILN_4338 GBV_ILN_4393 42.30 Mikrobiologie VZ 58.30 Biotechnologie VZ 58.34 Lebensmitteltechnologie VZ AR 122 |
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Structural characterization and protective effect on PC12 cells against H 2 O 2 -induced oxidative damage of a polysaccharide from Isaria cicadae Miquel mycelium and its zinc derivative |
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title_full |
Structural characterization and protective effect on PC12 cells against H 2 O 2 -induced oxidative damage of a polysaccharide from Isaria cicadae Miquel mycelium and its zinc derivative |
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Wang, Siqiang |
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Process biochemistry |
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eng |
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500 - Science |
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2022 |
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Wang, Siqiang Yang, Ximei Hou, Xuening Zhu, Zhenyuan |
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Wang, Siqiang |
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10.1016/j.procbio.2022.10.022 |
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530 |
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title_sort |
structural characterization and protective effect on pc12 cells against h 2 o 2 -induced oxidative damage of a polysaccharide from isaria cicadae miquel mycelium and its zinc derivative |
title_auth |
Structural characterization and protective effect on PC12 cells against H 2 O 2 -induced oxidative damage of a polysaccharide from Isaria cicadae Miquel mycelium and its zinc derivative |
abstract |
A homogeneous polysaccharide, ICMP-1, was isolated from the cultured mycelia of Isaria cicadae Miquel by hot water extraction. ICMP-1 (3.87 ×103 kDa) was a heteropolysaccharide mainly consisting of T-α-D-Glcp, →4)-α-D-Glcp-(1→, →4,6)-α-D-Manp-(1→, and →4)-β-D-Galp-(1→. In order to improve the antioxidant activity and the potential applications of ICMP-1, a typical ZnCl2 modification on ICMP-1 was carried out. Fourier-transform infrared spectroscopy (FT-IR), Energy dispersive spectrometer (EDS), scanning electron microscopy (SEM), atomic force microscope (AFM) and X-ray photoelectron spectroscopy (XPS) analysis confirmed that Zn was successfully introduced into the polymer chain of ICMP-1. The zinc modification derivative (ICMP-1-Zn) can alleviate H2O2-induced oxidative damage on PC12 cells. The stronger antioxidant activity of ICMP-1-Zn may be achieved by promoting the activity of zinc-containing enzymes, such as superoxide dismutase and lactate dehydrogenase. |
abstractGer |
A homogeneous polysaccharide, ICMP-1, was isolated from the cultured mycelia of Isaria cicadae Miquel by hot water extraction. ICMP-1 (3.87 ×103 kDa) was a heteropolysaccharide mainly consisting of T-α-D-Glcp, →4)-α-D-Glcp-(1→, →4,6)-α-D-Manp-(1→, and →4)-β-D-Galp-(1→. In order to improve the antioxidant activity and the potential applications of ICMP-1, a typical ZnCl2 modification on ICMP-1 was carried out. Fourier-transform infrared spectroscopy (FT-IR), Energy dispersive spectrometer (EDS), scanning electron microscopy (SEM), atomic force microscope (AFM) and X-ray photoelectron spectroscopy (XPS) analysis confirmed that Zn was successfully introduced into the polymer chain of ICMP-1. The zinc modification derivative (ICMP-1-Zn) can alleviate H2O2-induced oxidative damage on PC12 cells. The stronger antioxidant activity of ICMP-1-Zn may be achieved by promoting the activity of zinc-containing enzymes, such as superoxide dismutase and lactate dehydrogenase. |
abstract_unstemmed |
A homogeneous polysaccharide, ICMP-1, was isolated from the cultured mycelia of Isaria cicadae Miquel by hot water extraction. ICMP-1 (3.87 ×103 kDa) was a heteropolysaccharide mainly consisting of T-α-D-Glcp, →4)-α-D-Glcp-(1→, →4,6)-α-D-Manp-(1→, and →4)-β-D-Galp-(1→. In order to improve the antioxidant activity and the potential applications of ICMP-1, a typical ZnCl2 modification on ICMP-1 was carried out. Fourier-transform infrared spectroscopy (FT-IR), Energy dispersive spectrometer (EDS), scanning electron microscopy (SEM), atomic force microscope (AFM) and X-ray photoelectron spectroscopy (XPS) analysis confirmed that Zn was successfully introduced into the polymer chain of ICMP-1. The zinc modification derivative (ICMP-1-Zn) can alleviate H2O2-induced oxidative damage on PC12 cells. The stronger antioxidant activity of ICMP-1-Zn may be achieved by promoting the activity of zinc-containing enzymes, such as superoxide dismutase and lactate dehydrogenase. |
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title_short |
Structural characterization and protective effect on PC12 cells against H 2 O 2 -induced oxidative damage of a polysaccharide from Isaria cicadae Miquel mycelium and its zinc derivative |
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Yang, Ximei Hou, Xuening Zhu, Zhenyuan |
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up_date |
2024-07-06T20:44:37.186Z |
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