Structural characterization and protective effect on PC12 cells against H 2 O 2 -induced oxidative damage of a polysaccharide from Isaria cicadae Miquel mycelium and its zinc derivative

A homogeneous polysaccharide, ICMP-1, was isolated from the cultured mycelia of Isaria cicadae Miquel by hot water extraction. ICMP-1 (3.87 ×103 kDa) was a heteropolysaccharide mainly consisting of T-α-D-Glcp, →4)-α-D-Glcp-(1→, →4,6)-α-D-Manp-(1→, and →4)-β-D-Galp-(1→. In order to improve the antiox...
Ausführliche Beschreibung

Gespeichert in:

Autor*in:	Wang, Siqiang [verfasserIn] Yang, Ximei [verfasserIn] Hou, Xuening [verfasserIn] Zhu, Zhenyuan [verfasserIn]

Format:	E-Artikel
Sprache:	Englisch

Erschienen:	2022

Schlagwörter:	Polysaccharides Polysaccharide-Zn complex Structural characterization Oxidative stress

Übergeordnetes Werk:	Enthalten in: Process biochemistry - Amsterdam [u.a.] : Elsevier Science, 1991, 122
Übergeordnetes Werk:	volume:122

DOI / URN:	10.1016/j.procbio.2022.10.022

Katalog-ID:	ELV008740232

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245	1	0	\|a Structural characterization and protective effect on PC12 cells against H 2 O 2 -induced oxidative damage of a polysaccharide from Isaria cicadae Miquel mycelium and its zinc derivative
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520			\|a A homogeneous polysaccharide, ICMP-1, was isolated from the cultured mycelia of Isaria cicadae Miquel by hot water extraction. ICMP-1 (3.87 ×103 kDa) was a heteropolysaccharide mainly consisting of T-α-D-Glcp, →4)-α-D-Glcp-(1→, →4,6)-α-D-Manp-(1→, and →4)-β-D-Galp-(1→. In order to improve the antioxidant activity and the potential applications of ICMP-1, a typical ZnCl2 modification on ICMP-1 was carried out. Fourier-transform infrared spectroscopy (FT-IR), Energy dispersive spectrometer (EDS), scanning electron microscopy (SEM), atomic force microscope (AFM) and X-ray photoelectron spectroscopy (XPS) analysis confirmed that Zn was successfully introduced into the polymer chain of ICMP-1. The zinc modification derivative (ICMP-1-Zn) can alleviate H2O2-induced oxidative damage on PC12 cells. The stronger antioxidant activity of ICMP-1-Zn may be achieved by promoting the activity of zinc-containing enzymes, such as superoxide dismutase and lactate dehydrogenase.
650		4	\|a Polysaccharides
650		4	\|a Polysaccharide-Zn complex
650		4	\|a Structural characterization
650		4	\|a Oxidative stress
700	1		\|a Yang, Ximei \|e verfasserin \|4 aut
700	1		\|a Hou, Xuening \|e verfasserin \|4 aut
700	1		\|a Zhu, Zhenyuan \|e verfasserin \|4 aut
773	0	8	\|i Enthalten in \|t Process biochemistry \|d Amsterdam [u.a.] : Elsevier Science, 1991 \|g 122 \|h Online-Ressource \|w (DE-627)320570916 \|w (DE-600)2016483-X \|w (DE-576)259484989 \|x 0032-9592 \|7 nnns
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publishDate	2022
allfields	10.1016/j.procbio.2022.10.022 doi (DE-627)ELV008740232 (ELSEVIER)S1359-5113(22)00379-8 DE-627 ger DE-627 rda eng 530 VZ 42.30 bkl 58.30 bkl 58.34 bkl Wang, Siqiang verfasserin aut Structural characterization and protective effect on PC12 cells against H 2 O 2 -induced oxidative damage of a polysaccharide from Isaria cicadae Miquel mycelium and its zinc derivative 2022 nicht spezifiziert zzz rdacontent Computermedien c rdamedia Online-Ressource cr rdacarrier A homogeneous polysaccharide, ICMP-1, was isolated from the cultured mycelia of Isaria cicadae Miquel by hot water extraction. ICMP-1 (3.87 ×103 kDa) was a heteropolysaccharide mainly consisting of T-α-D-Glcp, →4)-α-D-Glcp-(1→, →4,6)-α-D-Manp-(1→, and →4)-β-D-Galp-(1→. In order to improve the antioxidant activity and the potential applications of ICMP-1, a typical ZnCl2 modification on ICMP-1 was carried out. Fourier-transform infrared spectroscopy (FT-IR), Energy dispersive spectrometer (EDS), scanning electron microscopy (SEM), atomic force microscope (AFM) and X-ray photoelectron spectroscopy (XPS) analysis confirmed that Zn was successfully introduced into the polymer chain of ICMP-1. The zinc modification derivative (ICMP-1-Zn) can alleviate H2O2-induced oxidative damage on PC12 cells. The stronger antioxidant activity of ICMP-1-Zn may be achieved by promoting the activity of zinc-containing enzymes, such as superoxide dismutase and lactate dehydrogenase. Polysaccharides Polysaccharide-Zn complex Structural characterization Oxidative stress Yang, Ximei verfasserin aut Hou, Xuening verfasserin aut Zhu, Zhenyuan verfasserin aut Enthalten in Process biochemistry Amsterdam [u.a.] : Elsevier Science, 1991 122 Online-Ressource (DE-627)320570916 (DE-600)2016483-X (DE-576)259484989 0032-9592 nnns volume:122 GBV_USEFLAG_U GBV_ELV SYSFLAG_U GBV_ILN_20 GBV_ILN_22 GBV_ILN_23 GBV_ILN_24 GBV_ILN_31 GBV_ILN_32 GBV_ILN_40 GBV_ILN_60 GBV_ILN_62 GBV_ILN_63 GBV_ILN_65 GBV_ILN_69 GBV_ILN_70 GBV_ILN_73 GBV_ILN_74 GBV_ILN_90 GBV_ILN_95 GBV_ILN_100 GBV_ILN_101 GBV_ILN_105 GBV_ILN_110 GBV_ILN_150 GBV_ILN_151 GBV_ILN_224 GBV_ILN_370 GBV_ILN_602 GBV_ILN_702 GBV_ILN_2003 GBV_ILN_2004 GBV_ILN_2005 GBV_ILN_2011 GBV_ILN_2014 GBV_ILN_2015 GBV_ILN_2020 GBV_ILN_2021 GBV_ILN_2025 GBV_ILN_2027 GBV_ILN_2034 GBV_ILN_2038 GBV_ILN_2044 GBV_ILN_2048 GBV_ILN_2049 GBV_ILN_2050 GBV_ILN_2056 GBV_ILN_2059 GBV_ILN_2061 GBV_ILN_2064 GBV_ILN_2065 GBV_ILN_2068 GBV_ILN_2111 GBV_ILN_2112 GBV_ILN_2113 GBV_ILN_2118 GBV_ILN_2122 GBV_ILN_2129 GBV_ILN_2143 GBV_ILN_2147 GBV_ILN_2148 GBV_ILN_2152 GBV_ILN_2153 GBV_ILN_2190 GBV_ILN_2336 GBV_ILN_2507 GBV_ILN_2522 GBV_ILN_4035 GBV_ILN_4037 GBV_ILN_4112 GBV_ILN_4125 GBV_ILN_4126 GBV_ILN_4242 GBV_ILN_4251 GBV_ILN_4305 GBV_ILN_4313 GBV_ILN_4323 GBV_ILN_4324 GBV_ILN_4326 GBV_ILN_4333 GBV_ILN_4334 GBV_ILN_4335 GBV_ILN_4338 GBV_ILN_4393 42.30 Mikrobiologie VZ 58.30 Biotechnologie VZ 58.34 Lebensmitteltechnologie VZ AR 122
spelling	10.1016/j.procbio.2022.10.022 doi (DE-627)ELV008740232 (ELSEVIER)S1359-5113(22)00379-8 DE-627 ger DE-627 rda eng 530 VZ 42.30 bkl 58.30 bkl 58.34 bkl Wang, Siqiang verfasserin aut Structural characterization and protective effect on PC12 cells against H 2 O 2 -induced oxidative damage of a polysaccharide from Isaria cicadae Miquel mycelium and its zinc derivative 2022 nicht spezifiziert zzz rdacontent Computermedien c rdamedia Online-Ressource cr rdacarrier A homogeneous polysaccharide, ICMP-1, was isolated from the cultured mycelia of Isaria cicadae Miquel by hot water extraction. ICMP-1 (3.87 ×103 kDa) was a heteropolysaccharide mainly consisting of T-α-D-Glcp, →4)-α-D-Glcp-(1→, →4,6)-α-D-Manp-(1→, and →4)-β-D-Galp-(1→. In order to improve the antioxidant activity and the potential applications of ICMP-1, a typical ZnCl2 modification on ICMP-1 was carried out. Fourier-transform infrared spectroscopy (FT-IR), Energy dispersive spectrometer (EDS), scanning electron microscopy (SEM), atomic force microscope (AFM) and X-ray photoelectron spectroscopy (XPS) analysis confirmed that Zn was successfully introduced into the polymer chain of ICMP-1. The zinc modification derivative (ICMP-1-Zn) can alleviate H2O2-induced oxidative damage on PC12 cells. The stronger antioxidant activity of ICMP-1-Zn may be achieved by promoting the activity of zinc-containing enzymes, such as superoxide dismutase and lactate dehydrogenase. Polysaccharides Polysaccharide-Zn complex Structural characterization Oxidative stress Yang, Ximei verfasserin aut Hou, Xuening verfasserin aut Zhu, Zhenyuan verfasserin aut Enthalten in Process biochemistry Amsterdam [u.a.] : Elsevier Science, 1991 122 Online-Ressource (DE-627)320570916 (DE-600)2016483-X (DE-576)259484989 0032-9592 nnns volume:122 GBV_USEFLAG_U GBV_ELV SYSFLAG_U GBV_ILN_20 GBV_ILN_22 GBV_ILN_23 GBV_ILN_24 GBV_ILN_31 GBV_ILN_32 GBV_ILN_40 GBV_ILN_60 GBV_ILN_62 GBV_ILN_63 GBV_ILN_65 GBV_ILN_69 GBV_ILN_70 GBV_ILN_73 GBV_ILN_74 GBV_ILN_90 GBV_ILN_95 GBV_ILN_100 GBV_ILN_101 GBV_ILN_105 GBV_ILN_110 GBV_ILN_150 GBV_ILN_151 GBV_ILN_224 GBV_ILN_370 GBV_ILN_602 GBV_ILN_702 GBV_ILN_2003 GBV_ILN_2004 GBV_ILN_2005 GBV_ILN_2011 GBV_ILN_2014 GBV_ILN_2015 GBV_ILN_2020 GBV_ILN_2021 GBV_ILN_2025 GBV_ILN_2027 GBV_ILN_2034 GBV_ILN_2038 GBV_ILN_2044 GBV_ILN_2048 GBV_ILN_2049 GBV_ILN_2050 GBV_ILN_2056 GBV_ILN_2059 GBV_ILN_2061 GBV_ILN_2064 GBV_ILN_2065 GBV_ILN_2068 GBV_ILN_2111 GBV_ILN_2112 GBV_ILN_2113 GBV_ILN_2118 GBV_ILN_2122 GBV_ILN_2129 GBV_ILN_2143 GBV_ILN_2147 GBV_ILN_2148 GBV_ILN_2152 GBV_ILN_2153 GBV_ILN_2190 GBV_ILN_2336 GBV_ILN_2507 GBV_ILN_2522 GBV_ILN_4035 GBV_ILN_4037 GBV_ILN_4112 GBV_ILN_4125 GBV_ILN_4126 GBV_ILN_4242 GBV_ILN_4251 GBV_ILN_4305 GBV_ILN_4313 GBV_ILN_4323 GBV_ILN_4324 GBV_ILN_4326 GBV_ILN_4333 GBV_ILN_4334 GBV_ILN_4335 GBV_ILN_4338 GBV_ILN_4393 42.30 Mikrobiologie VZ 58.30 Biotechnologie VZ 58.34 Lebensmitteltechnologie VZ AR 122
allfields_unstemmed	10.1016/j.procbio.2022.10.022 doi (DE-627)ELV008740232 (ELSEVIER)S1359-5113(22)00379-8 DE-627 ger DE-627 rda eng 530 VZ 42.30 bkl 58.30 bkl 58.34 bkl Wang, Siqiang verfasserin aut Structural characterization and protective effect on PC12 cells against H 2 O 2 -induced oxidative damage of a polysaccharide from Isaria cicadae Miquel mycelium and its zinc derivative 2022 nicht spezifiziert zzz rdacontent Computermedien c rdamedia Online-Ressource cr rdacarrier A homogeneous polysaccharide, ICMP-1, was isolated from the cultured mycelia of Isaria cicadae Miquel by hot water extraction. ICMP-1 (3.87 ×103 kDa) was a heteropolysaccharide mainly consisting of T-α-D-Glcp, →4)-α-D-Glcp-(1→, →4,6)-α-D-Manp-(1→, and →4)-β-D-Galp-(1→. In order to improve the antioxidant activity and the potential applications of ICMP-1, a typical ZnCl2 modification on ICMP-1 was carried out. Fourier-transform infrared spectroscopy (FT-IR), Energy dispersive spectrometer (EDS), scanning electron microscopy (SEM), atomic force microscope (AFM) and X-ray photoelectron spectroscopy (XPS) analysis confirmed that Zn was successfully introduced into the polymer chain of ICMP-1. The zinc modification derivative (ICMP-1-Zn) can alleviate H2O2-induced oxidative damage on PC12 cells. The stronger antioxidant activity of ICMP-1-Zn may be achieved by promoting the activity of zinc-containing enzymes, such as superoxide dismutase and lactate dehydrogenase. Polysaccharides Polysaccharide-Zn complex Structural characterization Oxidative stress Yang, Ximei verfasserin aut Hou, Xuening verfasserin aut Zhu, Zhenyuan verfasserin aut Enthalten in Process biochemistry Amsterdam [u.a.] : Elsevier Science, 1991 122 Online-Ressource (DE-627)320570916 (DE-600)2016483-X (DE-576)259484989 0032-9592 nnns volume:122 GBV_USEFLAG_U GBV_ELV SYSFLAG_U GBV_ILN_20 GBV_ILN_22 GBV_ILN_23 GBV_ILN_24 GBV_ILN_31 GBV_ILN_32 GBV_ILN_40 GBV_ILN_60 GBV_ILN_62 GBV_ILN_63 GBV_ILN_65 GBV_ILN_69 GBV_ILN_70 GBV_ILN_73 GBV_ILN_74 GBV_ILN_90 GBV_ILN_95 GBV_ILN_100 GBV_ILN_101 GBV_ILN_105 GBV_ILN_110 GBV_ILN_150 GBV_ILN_151 GBV_ILN_224 GBV_ILN_370 GBV_ILN_602 GBV_ILN_702 GBV_ILN_2003 GBV_ILN_2004 GBV_ILN_2005 GBV_ILN_2011 GBV_ILN_2014 GBV_ILN_2015 GBV_ILN_2020 GBV_ILN_2021 GBV_ILN_2025 GBV_ILN_2027 GBV_ILN_2034 GBV_ILN_2038 GBV_ILN_2044 GBV_ILN_2048 GBV_ILN_2049 GBV_ILN_2050 GBV_ILN_2056 GBV_ILN_2059 GBV_ILN_2061 GBV_ILN_2064 GBV_ILN_2065 GBV_ILN_2068 GBV_ILN_2111 GBV_ILN_2112 GBV_ILN_2113 GBV_ILN_2118 GBV_ILN_2122 GBV_ILN_2129 GBV_ILN_2143 GBV_ILN_2147 GBV_ILN_2148 GBV_ILN_2152 GBV_ILN_2153 GBV_ILN_2190 GBV_ILN_2336 GBV_ILN_2507 GBV_ILN_2522 GBV_ILN_4035 GBV_ILN_4037 GBV_ILN_4112 GBV_ILN_4125 GBV_ILN_4126 GBV_ILN_4242 GBV_ILN_4251 GBV_ILN_4305 GBV_ILN_4313 GBV_ILN_4323 GBV_ILN_4324 GBV_ILN_4326 GBV_ILN_4333 GBV_ILN_4334 GBV_ILN_4335 GBV_ILN_4338 GBV_ILN_4393 42.30 Mikrobiologie VZ 58.30 Biotechnologie VZ 58.34 Lebensmitteltechnologie VZ AR 122
allfieldsGer	10.1016/j.procbio.2022.10.022 doi (DE-627)ELV008740232 (ELSEVIER)S1359-5113(22)00379-8 DE-627 ger DE-627 rda eng 530 VZ 42.30 bkl 58.30 bkl 58.34 bkl Wang, Siqiang verfasserin aut Structural characterization and protective effect on PC12 cells against H 2 O 2 -induced oxidative damage of a polysaccharide from Isaria cicadae Miquel mycelium and its zinc derivative 2022 nicht spezifiziert zzz rdacontent Computermedien c rdamedia Online-Ressource cr rdacarrier A homogeneous polysaccharide, ICMP-1, was isolated from the cultured mycelia of Isaria cicadae Miquel by hot water extraction. ICMP-1 (3.87 ×103 kDa) was a heteropolysaccharide mainly consisting of T-α-D-Glcp, →4)-α-D-Glcp-(1→, →4,6)-α-D-Manp-(1→, and →4)-β-D-Galp-(1→. In order to improve the antioxidant activity and the potential applications of ICMP-1, a typical ZnCl2 modification on ICMP-1 was carried out. Fourier-transform infrared spectroscopy (FT-IR), Energy dispersive spectrometer (EDS), scanning electron microscopy (SEM), atomic force microscope (AFM) and X-ray photoelectron spectroscopy (XPS) analysis confirmed that Zn was successfully introduced into the polymer chain of ICMP-1. The zinc modification derivative (ICMP-1-Zn) can alleviate H2O2-induced oxidative damage on PC12 cells. The stronger antioxidant activity of ICMP-1-Zn may be achieved by promoting the activity of zinc-containing enzymes, such as superoxide dismutase and lactate dehydrogenase. Polysaccharides Polysaccharide-Zn complex Structural characterization Oxidative stress Yang, Ximei verfasserin aut Hou, Xuening verfasserin aut Zhu, Zhenyuan verfasserin aut Enthalten in Process biochemistry Amsterdam [u.a.] : Elsevier Science, 1991 122 Online-Ressource (DE-627)320570916 (DE-600)2016483-X (DE-576)259484989 0032-9592 nnns volume:122 GBV_USEFLAG_U GBV_ELV SYSFLAG_U GBV_ILN_20 GBV_ILN_22 GBV_ILN_23 GBV_ILN_24 GBV_ILN_31 GBV_ILN_32 GBV_ILN_40 GBV_ILN_60 GBV_ILN_62 GBV_ILN_63 GBV_ILN_65 GBV_ILN_69 GBV_ILN_70 GBV_ILN_73 GBV_ILN_74 GBV_ILN_90 GBV_ILN_95 GBV_ILN_100 GBV_ILN_101 GBV_ILN_105 GBV_ILN_110 GBV_ILN_150 GBV_ILN_151 GBV_ILN_224 GBV_ILN_370 GBV_ILN_602 GBV_ILN_702 GBV_ILN_2003 GBV_ILN_2004 GBV_ILN_2005 GBV_ILN_2011 GBV_ILN_2014 GBV_ILN_2015 GBV_ILN_2020 GBV_ILN_2021 GBV_ILN_2025 GBV_ILN_2027 GBV_ILN_2034 GBV_ILN_2038 GBV_ILN_2044 GBV_ILN_2048 GBV_ILN_2049 GBV_ILN_2050 GBV_ILN_2056 GBV_ILN_2059 GBV_ILN_2061 GBV_ILN_2064 GBV_ILN_2065 GBV_ILN_2068 GBV_ILN_2111 GBV_ILN_2112 GBV_ILN_2113 GBV_ILN_2118 GBV_ILN_2122 GBV_ILN_2129 GBV_ILN_2143 GBV_ILN_2147 GBV_ILN_2148 GBV_ILN_2152 GBV_ILN_2153 GBV_ILN_2190 GBV_ILN_2336 GBV_ILN_2507 GBV_ILN_2522 GBV_ILN_4035 GBV_ILN_4037 GBV_ILN_4112 GBV_ILN_4125 GBV_ILN_4126 GBV_ILN_4242 GBV_ILN_4251 GBV_ILN_4305 GBV_ILN_4313 GBV_ILN_4323 GBV_ILN_4324 GBV_ILN_4326 GBV_ILN_4333 GBV_ILN_4334 GBV_ILN_4335 GBV_ILN_4338 GBV_ILN_4393 42.30 Mikrobiologie VZ 58.30 Biotechnologie VZ 58.34 Lebensmitteltechnologie VZ AR 122
allfieldsSound	10.1016/j.procbio.2022.10.022 doi (DE-627)ELV008740232 (ELSEVIER)S1359-5113(22)00379-8 DE-627 ger DE-627 rda eng 530 VZ 42.30 bkl 58.30 bkl 58.34 bkl Wang, Siqiang verfasserin aut Structural characterization and protective effect on PC12 cells against H 2 O 2 -induced oxidative damage of a polysaccharide from Isaria cicadae Miquel mycelium and its zinc derivative 2022 nicht spezifiziert zzz rdacontent Computermedien c rdamedia Online-Ressource cr rdacarrier A homogeneous polysaccharide, ICMP-1, was isolated from the cultured mycelia of Isaria cicadae Miquel by hot water extraction. ICMP-1 (3.87 ×103 kDa) was a heteropolysaccharide mainly consisting of T-α-D-Glcp, →4)-α-D-Glcp-(1→, →4,6)-α-D-Manp-(1→, and →4)-β-D-Galp-(1→. In order to improve the antioxidant activity and the potential applications of ICMP-1, a typical ZnCl2 modification on ICMP-1 was carried out. Fourier-transform infrared spectroscopy (FT-IR), Energy dispersive spectrometer (EDS), scanning electron microscopy (SEM), atomic force microscope (AFM) and X-ray photoelectron spectroscopy (XPS) analysis confirmed that Zn was successfully introduced into the polymer chain of ICMP-1. The zinc modification derivative (ICMP-1-Zn) can alleviate H2O2-induced oxidative damage on PC12 cells. The stronger antioxidant activity of ICMP-1-Zn may be achieved by promoting the activity of zinc-containing enzymes, such as superoxide dismutase and lactate dehydrogenase. Polysaccharides Polysaccharide-Zn complex Structural characterization Oxidative stress Yang, Ximei verfasserin aut Hou, Xuening verfasserin aut Zhu, Zhenyuan verfasserin aut Enthalten in Process biochemistry Amsterdam [u.a.] : Elsevier Science, 1991 122 Online-Ressource (DE-627)320570916 (DE-600)2016483-X (DE-576)259484989 0032-9592 nnns volume:122 GBV_USEFLAG_U GBV_ELV SYSFLAG_U GBV_ILN_20 GBV_ILN_22 GBV_ILN_23 GBV_ILN_24 GBV_ILN_31 GBV_ILN_32 GBV_ILN_40 GBV_ILN_60 GBV_ILN_62 GBV_ILN_63 GBV_ILN_65 GBV_ILN_69 GBV_ILN_70 GBV_ILN_73 GBV_ILN_74 GBV_ILN_90 GBV_ILN_95 GBV_ILN_100 GBV_ILN_101 GBV_ILN_105 GBV_ILN_110 GBV_ILN_150 GBV_ILN_151 GBV_ILN_224 GBV_ILN_370 GBV_ILN_602 GBV_ILN_702 GBV_ILN_2003 GBV_ILN_2004 GBV_ILN_2005 GBV_ILN_2011 GBV_ILN_2014 GBV_ILN_2015 GBV_ILN_2020 GBV_ILN_2021 GBV_ILN_2025 GBV_ILN_2027 GBV_ILN_2034 GBV_ILN_2038 GBV_ILN_2044 GBV_ILN_2048 GBV_ILN_2049 GBV_ILN_2050 GBV_ILN_2056 GBV_ILN_2059 GBV_ILN_2061 GBV_ILN_2064 GBV_ILN_2065 GBV_ILN_2068 GBV_ILN_2111 GBV_ILN_2112 GBV_ILN_2113 GBV_ILN_2118 GBV_ILN_2122 GBV_ILN_2129 GBV_ILN_2143 GBV_ILN_2147 GBV_ILN_2148 GBV_ILN_2152 GBV_ILN_2153 GBV_ILN_2190 GBV_ILN_2336 GBV_ILN_2507 GBV_ILN_2522 GBV_ILN_4035 GBV_ILN_4037 GBV_ILN_4112 GBV_ILN_4125 GBV_ILN_4126 GBV_ILN_4242 GBV_ILN_4251 GBV_ILN_4305 GBV_ILN_4313 GBV_ILN_4323 GBV_ILN_4324 GBV_ILN_4326 GBV_ILN_4333 GBV_ILN_4334 GBV_ILN_4335 GBV_ILN_4338 GBV_ILN_4393 42.30 Mikrobiologie VZ 58.30 Biotechnologie VZ 58.34 Lebensmitteltechnologie VZ AR 122
language	English
source	Enthalten in Process biochemistry 122 volume:122
sourceStr	Enthalten in Process biochemistry 122 volume:122
format_phy_str_mv	Article
bklname	Mikrobiologie Biotechnologie Lebensmitteltechnologie
institution	findex.gbv.de
topic_facet	Polysaccharides Polysaccharide-Zn complex Structural characterization Oxidative stress
dewey-raw	530
isfreeaccess_bool	false
container_title	Process biochemistry
authorswithroles_txt_mv	Wang, Siqiang @@aut@@ Yang, Ximei @@aut@@ Hou, Xuening @@aut@@ Zhu, Zhenyuan @@aut@@
publishDateDaySort_date	2022-01-01T00:00:00Z
hierarchy_top_id	320570916
dewey-sort	3530
id	ELV008740232
language_de	englisch
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author	Wang, Siqiang
spellingShingle	Wang, Siqiang ddc 530 bkl 42.30 bkl 58.30 bkl 58.34 misc Polysaccharides misc Polysaccharide-Zn complex misc Structural characterization misc Oxidative stress Structural characterization and protective effect on PC12 cells against H 2 O 2 -induced oxidative damage of a polysaccharide from Isaria cicadae Miquel mycelium and its zinc derivative
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topic_title	530 VZ 42.30 bkl 58.30 bkl 58.34 bkl Structural characterization and protective effect on PC12 cells against H 2 O 2 -induced oxidative damage of a polysaccharide from Isaria cicadae Miquel mycelium and its zinc derivative Polysaccharides Polysaccharide-Zn complex Structural characterization Oxidative stress
topic	ddc 530 bkl 42.30 bkl 58.30 bkl 58.34 misc Polysaccharides misc Polysaccharide-Zn complex misc Structural characterization misc Oxidative stress
topic_unstemmed	ddc 530 bkl 42.30 bkl 58.30 bkl 58.34 misc Polysaccharides misc Polysaccharide-Zn complex misc Structural characterization misc Oxidative stress
topic_browse	ddc 530 bkl 42.30 bkl 58.30 bkl 58.34 misc Polysaccharides misc Polysaccharide-Zn complex misc Structural characterization misc Oxidative stress
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title	Structural characterization and protective effect on PC12 cells against H 2 O 2 -induced oxidative damage of a polysaccharide from Isaria cicadae Miquel mycelium and its zinc derivative
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title_full	Structural characterization and protective effect on PC12 cells against H 2 O 2 -induced oxidative damage of a polysaccharide from Isaria cicadae Miquel mycelium and its zinc derivative
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author_browse	Wang, Siqiang Yang, Ximei Hou, Xuening Zhu, Zhenyuan
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doi_str_mv	10.1016/j.procbio.2022.10.022
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title_sort	structural characterization and protective effect on pc12 cells against h 2 o 2 -induced oxidative damage of a polysaccharide from isaria cicadae miquel mycelium and its zinc derivative
title_auth	Structural characterization and protective effect on PC12 cells against H 2 O 2 -induced oxidative damage of a polysaccharide from Isaria cicadae Miquel mycelium and its zinc derivative
abstract	A homogeneous polysaccharide, ICMP-1, was isolated from the cultured mycelia of Isaria cicadae Miquel by hot water extraction. ICMP-1 (3.87 ×103 kDa) was a heteropolysaccharide mainly consisting of T-α-D-Glcp, →4)-α-D-Glcp-(1→, →4,6)-α-D-Manp-(1→, and →4)-β-D-Galp-(1→. In order to improve the antioxidant activity and the potential applications of ICMP-1, a typical ZnCl2 modification on ICMP-1 was carried out. Fourier-transform infrared spectroscopy (FT-IR), Energy dispersive spectrometer (EDS), scanning electron microscopy (SEM), atomic force microscope (AFM) and X-ray photoelectron spectroscopy (XPS) analysis confirmed that Zn was successfully introduced into the polymer chain of ICMP-1. The zinc modification derivative (ICMP-1-Zn) can alleviate H2O2-induced oxidative damage on PC12 cells. The stronger antioxidant activity of ICMP-1-Zn may be achieved by promoting the activity of zinc-containing enzymes, such as superoxide dismutase and lactate dehydrogenase.
abstractGer	A homogeneous polysaccharide, ICMP-1, was isolated from the cultured mycelia of Isaria cicadae Miquel by hot water extraction. ICMP-1 (3.87 ×103 kDa) was a heteropolysaccharide mainly consisting of T-α-D-Glcp, →4)-α-D-Glcp-(1→, →4,6)-α-D-Manp-(1→, and →4)-β-D-Galp-(1→. In order to improve the antioxidant activity and the potential applications of ICMP-1, a typical ZnCl2 modification on ICMP-1 was carried out. Fourier-transform infrared spectroscopy (FT-IR), Energy dispersive spectrometer (EDS), scanning electron microscopy (SEM), atomic force microscope (AFM) and X-ray photoelectron spectroscopy (XPS) analysis confirmed that Zn was successfully introduced into the polymer chain of ICMP-1. The zinc modification derivative (ICMP-1-Zn) can alleviate H2O2-induced oxidative damage on PC12 cells. The stronger antioxidant activity of ICMP-1-Zn may be achieved by promoting the activity of zinc-containing enzymes, such as superoxide dismutase and lactate dehydrogenase.
abstract_unstemmed	A homogeneous polysaccharide, ICMP-1, was isolated from the cultured mycelia of Isaria cicadae Miquel by hot water extraction. ICMP-1 (3.87 ×103 kDa) was a heteropolysaccharide mainly consisting of T-α-D-Glcp, →4)-α-D-Glcp-(1→, →4,6)-α-D-Manp-(1→, and →4)-β-D-Galp-(1→. In order to improve the antioxidant activity and the potential applications of ICMP-1, a typical ZnCl2 modification on ICMP-1 was carried out. Fourier-transform infrared spectroscopy (FT-IR), Energy dispersive spectrometer (EDS), scanning electron microscopy (SEM), atomic force microscope (AFM) and X-ray photoelectron spectroscopy (XPS) analysis confirmed that Zn was successfully introduced into the polymer chain of ICMP-1. The zinc modification derivative (ICMP-1-Zn) can alleviate H2O2-induced oxidative damage on PC12 cells. The stronger antioxidant activity of ICMP-1-Zn may be achieved by promoting the activity of zinc-containing enzymes, such as superoxide dismutase and lactate dehydrogenase.
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title_short	Structural characterization and protective effect on PC12 cells against H 2 O 2 -induced oxidative damage of a polysaccharide from Isaria cicadae Miquel mycelium and its zinc derivative
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doi_str	10.1016/j.procbio.2022.10.022
up_date	2024-07-06T20:44:37.186Z
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Structural characterization and protective effect on PC12 cells against H 2 O 2 -induced oxidative damage of a polysaccharide from Isaria cicadae Miquel mycelium and its zinc derivative

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