Phosphodiesterases type 2, 3 and 4 promote vascular tone in mesenteric arteries from rats with heart failure

Phosphodiesterases (PDE) type 3 and 4 promote vasoconstriction by hydrolysing cAMP. In experimental heart failure (HF), PDE3 makes PDE4 redundant in aorta, but it is not known if this occurs in resistance vessels, such as mesenteric artery. As PDE2 is increased in the failing myocardium, its possibl...
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Autor*in:	Wang, Liting [verfasserIn] Hubert, Fabien [verfasserIn] Idres, Sarah [verfasserIn] Belacel-Ouari, Milia [verfasserIn] Domergue, Valérie [verfasserIn] Domenichini, Séverine [verfasserIn] Lefebvre, Florence [verfasserIn] Mika, Delphine [verfasserIn] Fischmeister, Rodolphe [verfasserIn] Leblais, Véronique [verfasserIn] Manoury, Boris [verfasserIn]

Format:	E-Artikel
Sprache:	Englisch

Erschienen:	2023

Schlagwörter:	Phosphodiesterase inhibitor Vascular tone Mesenteric artery Heart failure Nitric oxide (NO)

Übergeordnetes Werk:	Enthalten in: European journal of pharmacology - New York, NY [u.a.] : Elsevier, 1967, 944
Übergeordnetes Werk:	volume:944

DOI / URN:	10.1016/j.ejphar.2023.175562

Katalog-ID:	ELV009321071

Internformat


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100	1		\|a Wang, Liting \|e verfasserin \|4 aut
245	1	0	\|a Phosphodiesterases type 2, 3 and 4 promote vascular tone in mesenteric arteries from rats with heart failure
264		1	\|c 2023
336			\|a nicht spezifiziert \|b zzz \|2 rdacontent
337			\|a Computermedien \|b c \|2 rdamedia
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520			\|a Phosphodiesterases (PDE) type 3 and 4 promote vasoconstriction by hydrolysing cAMP. In experimental heart failure (HF), PDE3 makes PDE4 redundant in aorta, but it is not known if this occurs in resistance vessels, such as mesenteric artery. As PDE2 is increased in the failing myocardium, its possible role in the vasculature also needs to be addressed. Here, the function of PDE2, PDE3 and PDE4 in rat mesenteric arteries was characterized in experimental HF.
650		4	\|a Phosphodiesterase inhibitor
650		4	\|a Vascular tone
650		4	\|a Mesenteric artery
650		4	\|a Heart failure
650		4	\|a Nitric oxide (NO)
700	1		\|a Hubert, Fabien \|e verfasserin \|4 aut
700	1		\|a Idres, Sarah \|e verfasserin \|4 aut
700	1		\|a Belacel-Ouari, Milia \|e verfasserin \|4 aut
700	1		\|a Domergue, Valérie \|e verfasserin \|4 aut
700	1		\|a Domenichini, Séverine \|e verfasserin \|4 aut
700	1		\|a Lefebvre, Florence \|e verfasserin \|4 aut
700	1		\|a Mika, Delphine \|e verfasserin \|4 aut
700	1		\|a Fischmeister, Rodolphe \|e verfasserin \|4 aut
700	1		\|a Leblais, Véronique \|e verfasserin \|4 aut
700	1		\|a Manoury, Boris \|e verfasserin \|0 (orcid)0000-0001-7305-5633 \|4 aut
773	0	8	\|i Enthalten in \|t European journal of pharmacology \|d New York, NY [u.a.] : Elsevier, 1967 \|g 944 \|h Online-Ressource \|w (DE-627)300897340 \|w (DE-600)1483526-5 \|w (DE-576)081952627 \|x 1879-0712 \|7 nnns
773	1	8	\|g volume:944
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912			\|a GBV_ILN_22
912			\|a GBV_ILN_23
912			\|a GBV_ILN_24
912			\|a GBV_ILN_31
912			\|a GBV_ILN_32
912			\|a GBV_ILN_40
912			\|a GBV_ILN_60
912			\|a GBV_ILN_62
912			\|a GBV_ILN_65
912			\|a GBV_ILN_69
912			\|a GBV_ILN_70
912			\|a GBV_ILN_73
912			\|a GBV_ILN_74
912			\|a GBV_ILN_90
912			\|a GBV_ILN_100
912			\|a GBV_ILN_101
912			\|a GBV_ILN_105
912			\|a GBV_ILN_110
912			\|a GBV_ILN_151
912			\|a GBV_ILN_187
912			\|a GBV_ILN_213
912			\|a GBV_ILN_224
912			\|a GBV_ILN_230
912			\|a GBV_ILN_370
912			\|a GBV_ILN_602
912			\|a GBV_ILN_702
912			\|a GBV_ILN_2001
912			\|a GBV_ILN_2003
912			\|a GBV_ILN_2004
912			\|a GBV_ILN_2005
912			\|a GBV_ILN_2007
912			\|a GBV_ILN_2009
912			\|a GBV_ILN_2010
912			\|a GBV_ILN_2011
912			\|a GBV_ILN_2014
912			\|a GBV_ILN_2015
912			\|a GBV_ILN_2020
912			\|a GBV_ILN_2021
912			\|a GBV_ILN_2025
912			\|a GBV_ILN_2026
912			\|a GBV_ILN_2027
912			\|a GBV_ILN_2034
912			\|a GBV_ILN_2044
912			\|a GBV_ILN_2048
912			\|a GBV_ILN_2049
912			\|a GBV_ILN_2050
912			\|a GBV_ILN_2055
912			\|a GBV_ILN_2056
912			\|a GBV_ILN_2059
912			\|a GBV_ILN_2061
912			\|a GBV_ILN_2064
912			\|a GBV_ILN_2106
912			\|a GBV_ILN_2110
912			\|a GBV_ILN_2111
912			\|a GBV_ILN_2112
912			\|a GBV_ILN_2122
912			\|a GBV_ILN_2129
912			\|a GBV_ILN_2143
912			\|a GBV_ILN_2152
912			\|a GBV_ILN_2153
912			\|a GBV_ILN_2190
912			\|a GBV_ILN_2232
912			\|a GBV_ILN_2336
912			\|a GBV_ILN_2470
912			\|a GBV_ILN_2507
912			\|a GBV_ILN_4035
912			\|a GBV_ILN_4037
912			\|a GBV_ILN_4112
912			\|a GBV_ILN_4125
912			\|a GBV_ILN_4242
912			\|a GBV_ILN_4249
912			\|a GBV_ILN_4251
912			\|a GBV_ILN_4305
912			\|a GBV_ILN_4306
912			\|a GBV_ILN_4307
912			\|a GBV_ILN_4313
912			\|a GBV_ILN_4322
912			\|a GBV_ILN_4323
912			\|a GBV_ILN_4324
912			\|a GBV_ILN_4326
912			\|a GBV_ILN_4333
912			\|a GBV_ILN_4334
912			\|a GBV_ILN_4338
912			\|a GBV_ILN_4393
912			\|a GBV_ILN_4700
936	b	k	\|a 44.38 \|j Pharmakologie
951			\|a AR
952			\|d 944

Indexfelder

author_variant	l w lw f h fh s i si m b o mbo v d vd s d sd f l fl d m dm r f rf v l vl b m bm
matchkey_str	article:18790712:2023----::hshdetrssye3n4rmtvsuatnimsneiatre
hierarchy_sort_str	2023
bklnumber	44.38
publishDate	2023
allfields	10.1016/j.ejphar.2023.175562 doi (DE-627)ELV009321071 (ELSEVIER)S0014-2999(23)00073-0 DE-627 ger DE-627 rda eng 610 DE-600 PHARM DE-84 fid 44.38 bkl Wang, Liting verfasserin aut Phosphodiesterases type 2, 3 and 4 promote vascular tone in mesenteric arteries from rats with heart failure 2023 nicht spezifiziert zzz rdacontent Computermedien c rdamedia Online-Ressource cr rdacarrier Phosphodiesterases (PDE) type 3 and 4 promote vasoconstriction by hydrolysing cAMP. In experimental heart failure (HF), PDE3 makes PDE4 redundant in aorta, but it is not known if this occurs in resistance vessels, such as mesenteric artery. As PDE2 is increased in the failing myocardium, its possible role in the vasculature also needs to be addressed. Here, the function of PDE2, PDE3 and PDE4 in rat mesenteric arteries was characterized in experimental HF. Phosphodiesterase inhibitor Vascular tone Mesenteric artery Heart failure Nitric oxide (NO) Hubert, Fabien verfasserin aut Idres, Sarah verfasserin aut Belacel-Ouari, Milia verfasserin aut Domergue, Valérie verfasserin aut Domenichini, Séverine verfasserin aut Lefebvre, Florence verfasserin aut Mika, Delphine verfasserin aut Fischmeister, Rodolphe verfasserin aut Leblais, Véronique verfasserin aut Manoury, Boris verfasserin (orcid)0000-0001-7305-5633 aut Enthalten in European journal of pharmacology New York, NY [u.a.] : Elsevier, 1967 944 Online-Ressource (DE-627)300897340 (DE-600)1483526-5 (DE-576)081952627 1879-0712 nnns volume:944 GBV_USEFLAG_U SYSFLAG_U GBV_ELV FID-PHARM SSG-OLC-PHA SSG-OPC-PHA GBV_ILN_20 GBV_ILN_22 GBV_ILN_23 GBV_ILN_24 GBV_ILN_31 GBV_ILN_32 GBV_ILN_40 GBV_ILN_60 GBV_ILN_62 GBV_ILN_65 GBV_ILN_69 GBV_ILN_70 GBV_ILN_73 GBV_ILN_74 GBV_ILN_90 GBV_ILN_100 GBV_ILN_101 GBV_ILN_105 GBV_ILN_110 GBV_ILN_151 GBV_ILN_187 GBV_ILN_213 GBV_ILN_224 GBV_ILN_230 GBV_ILN_370 GBV_ILN_602 GBV_ILN_702 GBV_ILN_2001 GBV_ILN_2003 GBV_ILN_2004 GBV_ILN_2005 GBV_ILN_2007 GBV_ILN_2009 GBV_ILN_2010 GBV_ILN_2011 GBV_ILN_2014 GBV_ILN_2015 GBV_ILN_2020 GBV_ILN_2021 GBV_ILN_2025 GBV_ILN_2026 GBV_ILN_2027 GBV_ILN_2034 GBV_ILN_2044 GBV_ILN_2048 GBV_ILN_2049 GBV_ILN_2050 GBV_ILN_2055 GBV_ILN_2056 GBV_ILN_2059 GBV_ILN_2061 GBV_ILN_2064 GBV_ILN_2106 GBV_ILN_2110 GBV_ILN_2111 GBV_ILN_2112 GBV_ILN_2122 GBV_ILN_2129 GBV_ILN_2143 GBV_ILN_2152 GBV_ILN_2153 GBV_ILN_2190 GBV_ILN_2232 GBV_ILN_2336 GBV_ILN_2470 GBV_ILN_2507 GBV_ILN_4035 GBV_ILN_4037 GBV_ILN_4112 GBV_ILN_4125 GBV_ILN_4242 GBV_ILN_4249 GBV_ILN_4251 GBV_ILN_4305 GBV_ILN_4306 GBV_ILN_4307 GBV_ILN_4313 GBV_ILN_4322 GBV_ILN_4323 GBV_ILN_4324 GBV_ILN_4326 GBV_ILN_4333 GBV_ILN_4334 GBV_ILN_4338 GBV_ILN_4393 GBV_ILN_4700 44.38 Pharmakologie AR 944
spelling	10.1016/j.ejphar.2023.175562 doi (DE-627)ELV009321071 (ELSEVIER)S0014-2999(23)00073-0 DE-627 ger DE-627 rda eng 610 DE-600 PHARM DE-84 fid 44.38 bkl Wang, Liting verfasserin aut Phosphodiesterases type 2, 3 and 4 promote vascular tone in mesenteric arteries from rats with heart failure 2023 nicht spezifiziert zzz rdacontent Computermedien c rdamedia Online-Ressource cr rdacarrier Phosphodiesterases (PDE) type 3 and 4 promote vasoconstriction by hydrolysing cAMP. In experimental heart failure (HF), PDE3 makes PDE4 redundant in aorta, but it is not known if this occurs in resistance vessels, such as mesenteric artery. As PDE2 is increased in the failing myocardium, its possible role in the vasculature also needs to be addressed. Here, the function of PDE2, PDE3 and PDE4 in rat mesenteric arteries was characterized in experimental HF. Phosphodiesterase inhibitor Vascular tone Mesenteric artery Heart failure Nitric oxide (NO) Hubert, Fabien verfasserin aut Idres, Sarah verfasserin aut Belacel-Ouari, Milia verfasserin aut Domergue, Valérie verfasserin aut Domenichini, Séverine verfasserin aut Lefebvre, Florence verfasserin aut Mika, Delphine verfasserin aut Fischmeister, Rodolphe verfasserin aut Leblais, Véronique verfasserin aut Manoury, Boris verfasserin (orcid)0000-0001-7305-5633 aut Enthalten in European journal of pharmacology New York, NY [u.a.] : Elsevier, 1967 944 Online-Ressource (DE-627)300897340 (DE-600)1483526-5 (DE-576)081952627 1879-0712 nnns volume:944 GBV_USEFLAG_U SYSFLAG_U GBV_ELV FID-PHARM SSG-OLC-PHA SSG-OPC-PHA GBV_ILN_20 GBV_ILN_22 GBV_ILN_23 GBV_ILN_24 GBV_ILN_31 GBV_ILN_32 GBV_ILN_40 GBV_ILN_60 GBV_ILN_62 GBV_ILN_65 GBV_ILN_69 GBV_ILN_70 GBV_ILN_73 GBV_ILN_74 GBV_ILN_90 GBV_ILN_100 GBV_ILN_101 GBV_ILN_105 GBV_ILN_110 GBV_ILN_151 GBV_ILN_187 GBV_ILN_213 GBV_ILN_224 GBV_ILN_230 GBV_ILN_370 GBV_ILN_602 GBV_ILN_702 GBV_ILN_2001 GBV_ILN_2003 GBV_ILN_2004 GBV_ILN_2005 GBV_ILN_2007 GBV_ILN_2009 GBV_ILN_2010 GBV_ILN_2011 GBV_ILN_2014 GBV_ILN_2015 GBV_ILN_2020 GBV_ILN_2021 GBV_ILN_2025 GBV_ILN_2026 GBV_ILN_2027 GBV_ILN_2034 GBV_ILN_2044 GBV_ILN_2048 GBV_ILN_2049 GBV_ILN_2050 GBV_ILN_2055 GBV_ILN_2056 GBV_ILN_2059 GBV_ILN_2061 GBV_ILN_2064 GBV_ILN_2106 GBV_ILN_2110 GBV_ILN_2111 GBV_ILN_2112 GBV_ILN_2122 GBV_ILN_2129 GBV_ILN_2143 GBV_ILN_2152 GBV_ILN_2153 GBV_ILN_2190 GBV_ILN_2232 GBV_ILN_2336 GBV_ILN_2470 GBV_ILN_2507 GBV_ILN_4035 GBV_ILN_4037 GBV_ILN_4112 GBV_ILN_4125 GBV_ILN_4242 GBV_ILN_4249 GBV_ILN_4251 GBV_ILN_4305 GBV_ILN_4306 GBV_ILN_4307 GBV_ILN_4313 GBV_ILN_4322 GBV_ILN_4323 GBV_ILN_4324 GBV_ILN_4326 GBV_ILN_4333 GBV_ILN_4334 GBV_ILN_4338 GBV_ILN_4393 GBV_ILN_4700 44.38 Pharmakologie AR 944
allfields_unstemmed	10.1016/j.ejphar.2023.175562 doi (DE-627)ELV009321071 (ELSEVIER)S0014-2999(23)00073-0 DE-627 ger DE-627 rda eng 610 DE-600 PHARM DE-84 fid 44.38 bkl Wang, Liting verfasserin aut Phosphodiesterases type 2, 3 and 4 promote vascular tone in mesenteric arteries from rats with heart failure 2023 nicht spezifiziert zzz rdacontent Computermedien c rdamedia Online-Ressource cr rdacarrier Phosphodiesterases (PDE) type 3 and 4 promote vasoconstriction by hydrolysing cAMP. In experimental heart failure (HF), PDE3 makes PDE4 redundant in aorta, but it is not known if this occurs in resistance vessels, such as mesenteric artery. As PDE2 is increased in the failing myocardium, its possible role in the vasculature also needs to be addressed. Here, the function of PDE2, PDE3 and PDE4 in rat mesenteric arteries was characterized in experimental HF. Phosphodiesterase inhibitor Vascular tone Mesenteric artery Heart failure Nitric oxide (NO) Hubert, Fabien verfasserin aut Idres, Sarah verfasserin aut Belacel-Ouari, Milia verfasserin aut Domergue, Valérie verfasserin aut Domenichini, Séverine verfasserin aut Lefebvre, Florence verfasserin aut Mika, Delphine verfasserin aut Fischmeister, Rodolphe verfasserin aut Leblais, Véronique verfasserin aut Manoury, Boris verfasserin (orcid)0000-0001-7305-5633 aut Enthalten in European journal of pharmacology New York, NY [u.a.] : Elsevier, 1967 944 Online-Ressource (DE-627)300897340 (DE-600)1483526-5 (DE-576)081952627 1879-0712 nnns volume:944 GBV_USEFLAG_U SYSFLAG_U GBV_ELV FID-PHARM SSG-OLC-PHA SSG-OPC-PHA GBV_ILN_20 GBV_ILN_22 GBV_ILN_23 GBV_ILN_24 GBV_ILN_31 GBV_ILN_32 GBV_ILN_40 GBV_ILN_60 GBV_ILN_62 GBV_ILN_65 GBV_ILN_69 GBV_ILN_70 GBV_ILN_73 GBV_ILN_74 GBV_ILN_90 GBV_ILN_100 GBV_ILN_101 GBV_ILN_105 GBV_ILN_110 GBV_ILN_151 GBV_ILN_187 GBV_ILN_213 GBV_ILN_224 GBV_ILN_230 GBV_ILN_370 GBV_ILN_602 GBV_ILN_702 GBV_ILN_2001 GBV_ILN_2003 GBV_ILN_2004 GBV_ILN_2005 GBV_ILN_2007 GBV_ILN_2009 GBV_ILN_2010 GBV_ILN_2011 GBV_ILN_2014 GBV_ILN_2015 GBV_ILN_2020 GBV_ILN_2021 GBV_ILN_2025 GBV_ILN_2026 GBV_ILN_2027 GBV_ILN_2034 GBV_ILN_2044 GBV_ILN_2048 GBV_ILN_2049 GBV_ILN_2050 GBV_ILN_2055 GBV_ILN_2056 GBV_ILN_2059 GBV_ILN_2061 GBV_ILN_2064 GBV_ILN_2106 GBV_ILN_2110 GBV_ILN_2111 GBV_ILN_2112 GBV_ILN_2122 GBV_ILN_2129 GBV_ILN_2143 GBV_ILN_2152 GBV_ILN_2153 GBV_ILN_2190 GBV_ILN_2232 GBV_ILN_2336 GBV_ILN_2470 GBV_ILN_2507 GBV_ILN_4035 GBV_ILN_4037 GBV_ILN_4112 GBV_ILN_4125 GBV_ILN_4242 GBV_ILN_4249 GBV_ILN_4251 GBV_ILN_4305 GBV_ILN_4306 GBV_ILN_4307 GBV_ILN_4313 GBV_ILN_4322 GBV_ILN_4323 GBV_ILN_4324 GBV_ILN_4326 GBV_ILN_4333 GBV_ILN_4334 GBV_ILN_4338 GBV_ILN_4393 GBV_ILN_4700 44.38 Pharmakologie AR 944
allfieldsGer	10.1016/j.ejphar.2023.175562 doi (DE-627)ELV009321071 (ELSEVIER)S0014-2999(23)00073-0 DE-627 ger DE-627 rda eng 610 DE-600 PHARM DE-84 fid 44.38 bkl Wang, Liting verfasserin aut Phosphodiesterases type 2, 3 and 4 promote vascular tone in mesenteric arteries from rats with heart failure 2023 nicht spezifiziert zzz rdacontent Computermedien c rdamedia Online-Ressource cr rdacarrier Phosphodiesterases (PDE) type 3 and 4 promote vasoconstriction by hydrolysing cAMP. In experimental heart failure (HF), PDE3 makes PDE4 redundant in aorta, but it is not known if this occurs in resistance vessels, such as mesenteric artery. As PDE2 is increased in the failing myocardium, its possible role in the vasculature also needs to be addressed. Here, the function of PDE2, PDE3 and PDE4 in rat mesenteric arteries was characterized in experimental HF. Phosphodiesterase inhibitor Vascular tone Mesenteric artery Heart failure Nitric oxide (NO) Hubert, Fabien verfasserin aut Idres, Sarah verfasserin aut Belacel-Ouari, Milia verfasserin aut Domergue, Valérie verfasserin aut Domenichini, Séverine verfasserin aut Lefebvre, Florence verfasserin aut Mika, Delphine verfasserin aut Fischmeister, Rodolphe verfasserin aut Leblais, Véronique verfasserin aut Manoury, Boris verfasserin (orcid)0000-0001-7305-5633 aut Enthalten in European journal of pharmacology New York, NY [u.a.] : Elsevier, 1967 944 Online-Ressource (DE-627)300897340 (DE-600)1483526-5 (DE-576)081952627 1879-0712 nnns volume:944 GBV_USEFLAG_U SYSFLAG_U GBV_ELV FID-PHARM SSG-OLC-PHA SSG-OPC-PHA GBV_ILN_20 GBV_ILN_22 GBV_ILN_23 GBV_ILN_24 GBV_ILN_31 GBV_ILN_32 GBV_ILN_40 GBV_ILN_60 GBV_ILN_62 GBV_ILN_65 GBV_ILN_69 GBV_ILN_70 GBV_ILN_73 GBV_ILN_74 GBV_ILN_90 GBV_ILN_100 GBV_ILN_101 GBV_ILN_105 GBV_ILN_110 GBV_ILN_151 GBV_ILN_187 GBV_ILN_213 GBV_ILN_224 GBV_ILN_230 GBV_ILN_370 GBV_ILN_602 GBV_ILN_702 GBV_ILN_2001 GBV_ILN_2003 GBV_ILN_2004 GBV_ILN_2005 GBV_ILN_2007 GBV_ILN_2009 GBV_ILN_2010 GBV_ILN_2011 GBV_ILN_2014 GBV_ILN_2015 GBV_ILN_2020 GBV_ILN_2021 GBV_ILN_2025 GBV_ILN_2026 GBV_ILN_2027 GBV_ILN_2034 GBV_ILN_2044 GBV_ILN_2048 GBV_ILN_2049 GBV_ILN_2050 GBV_ILN_2055 GBV_ILN_2056 GBV_ILN_2059 GBV_ILN_2061 GBV_ILN_2064 GBV_ILN_2106 GBV_ILN_2110 GBV_ILN_2111 GBV_ILN_2112 GBV_ILN_2122 GBV_ILN_2129 GBV_ILN_2143 GBV_ILN_2152 GBV_ILN_2153 GBV_ILN_2190 GBV_ILN_2232 GBV_ILN_2336 GBV_ILN_2470 GBV_ILN_2507 GBV_ILN_4035 GBV_ILN_4037 GBV_ILN_4112 GBV_ILN_4125 GBV_ILN_4242 GBV_ILN_4249 GBV_ILN_4251 GBV_ILN_4305 GBV_ILN_4306 GBV_ILN_4307 GBV_ILN_4313 GBV_ILN_4322 GBV_ILN_4323 GBV_ILN_4324 GBV_ILN_4326 GBV_ILN_4333 GBV_ILN_4334 GBV_ILN_4338 GBV_ILN_4393 GBV_ILN_4700 44.38 Pharmakologie AR 944
allfieldsSound	10.1016/j.ejphar.2023.175562 doi (DE-627)ELV009321071 (ELSEVIER)S0014-2999(23)00073-0 DE-627 ger DE-627 rda eng 610 DE-600 PHARM DE-84 fid 44.38 bkl Wang, Liting verfasserin aut Phosphodiesterases type 2, 3 and 4 promote vascular tone in mesenteric arteries from rats with heart failure 2023 nicht spezifiziert zzz rdacontent Computermedien c rdamedia Online-Ressource cr rdacarrier Phosphodiesterases (PDE) type 3 and 4 promote vasoconstriction by hydrolysing cAMP. In experimental heart failure (HF), PDE3 makes PDE4 redundant in aorta, but it is not known if this occurs in resistance vessels, such as mesenteric artery. As PDE2 is increased in the failing myocardium, its possible role in the vasculature also needs to be addressed. Here, the function of PDE2, PDE3 and PDE4 in rat mesenteric arteries was characterized in experimental HF. Phosphodiesterase inhibitor Vascular tone Mesenteric artery Heart failure Nitric oxide (NO) Hubert, Fabien verfasserin aut Idres, Sarah verfasserin aut Belacel-Ouari, Milia verfasserin aut Domergue, Valérie verfasserin aut Domenichini, Séverine verfasserin aut Lefebvre, Florence verfasserin aut Mika, Delphine verfasserin aut Fischmeister, Rodolphe verfasserin aut Leblais, Véronique verfasserin aut Manoury, Boris verfasserin (orcid)0000-0001-7305-5633 aut Enthalten in European journal of pharmacology New York, NY [u.a.] : Elsevier, 1967 944 Online-Ressource (DE-627)300897340 (DE-600)1483526-5 (DE-576)081952627 1879-0712 nnns volume:944 GBV_USEFLAG_U SYSFLAG_U GBV_ELV FID-PHARM SSG-OLC-PHA SSG-OPC-PHA GBV_ILN_20 GBV_ILN_22 GBV_ILN_23 GBV_ILN_24 GBV_ILN_31 GBV_ILN_32 GBV_ILN_40 GBV_ILN_60 GBV_ILN_62 GBV_ILN_65 GBV_ILN_69 GBV_ILN_70 GBV_ILN_73 GBV_ILN_74 GBV_ILN_90 GBV_ILN_100 GBV_ILN_101 GBV_ILN_105 GBV_ILN_110 GBV_ILN_151 GBV_ILN_187 GBV_ILN_213 GBV_ILN_224 GBV_ILN_230 GBV_ILN_370 GBV_ILN_602 GBV_ILN_702 GBV_ILN_2001 GBV_ILN_2003 GBV_ILN_2004 GBV_ILN_2005 GBV_ILN_2007 GBV_ILN_2009 GBV_ILN_2010 GBV_ILN_2011 GBV_ILN_2014 GBV_ILN_2015 GBV_ILN_2020 GBV_ILN_2021 GBV_ILN_2025 GBV_ILN_2026 GBV_ILN_2027 GBV_ILN_2034 GBV_ILN_2044 GBV_ILN_2048 GBV_ILN_2049 GBV_ILN_2050 GBV_ILN_2055 GBV_ILN_2056 GBV_ILN_2059 GBV_ILN_2061 GBV_ILN_2064 GBV_ILN_2106 GBV_ILN_2110 GBV_ILN_2111 GBV_ILN_2112 GBV_ILN_2122 GBV_ILN_2129 GBV_ILN_2143 GBV_ILN_2152 GBV_ILN_2153 GBV_ILN_2190 GBV_ILN_2232 GBV_ILN_2336 GBV_ILN_2470 GBV_ILN_2507 GBV_ILN_4035 GBV_ILN_4037 GBV_ILN_4112 GBV_ILN_4125 GBV_ILN_4242 GBV_ILN_4249 GBV_ILN_4251 GBV_ILN_4305 GBV_ILN_4306 GBV_ILN_4307 GBV_ILN_4313 GBV_ILN_4322 GBV_ILN_4323 GBV_ILN_4324 GBV_ILN_4326 GBV_ILN_4333 GBV_ILN_4334 GBV_ILN_4338 GBV_ILN_4393 GBV_ILN_4700 44.38 Pharmakologie AR 944
language	English
source	Enthalten in European journal of pharmacology 944 volume:944
sourceStr	Enthalten in European journal of pharmacology 944 volume:944
format_phy_str_mv	Article
bklname	Pharmakologie
institution	findex.gbv.de
topic_facet	Phosphodiesterase inhibitor Vascular tone Mesenteric artery Heart failure Nitric oxide (NO)
dewey-raw	610
isfreeaccess_bool	false
container_title	European journal of pharmacology
authorswithroles_txt_mv	Wang, Liting @@aut@@ Hubert, Fabien @@aut@@ Idres, Sarah @@aut@@ Belacel-Ouari, Milia @@aut@@ Domergue, Valérie @@aut@@ Domenichini, Séverine @@aut@@ Lefebvre, Florence @@aut@@ Mika, Delphine @@aut@@ Fischmeister, Rodolphe @@aut@@ Leblais, Véronique @@aut@@ Manoury, Boris @@aut@@
publishDateDaySort_date	2023-01-01T00:00:00Z
hierarchy_top_id	300897340
dewey-sort	3610
id	ELV009321071
language_de	englisch
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author	Wang, Liting
spellingShingle	Wang, Liting ddc 610 fid PHARM bkl 44.38 misc Phosphodiesterase inhibitor misc Vascular tone misc Mesenteric artery misc Heart failure misc Nitric oxide (NO) Phosphodiesterases type 2, 3 and 4 promote vascular tone in mesenteric arteries from rats with heart failure
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topic_title	610 DE-600 PHARM DE-84 fid 44.38 bkl Phosphodiesterases type 2, 3 and 4 promote vascular tone in mesenteric arteries from rats with heart failure Phosphodiesterase inhibitor Vascular tone Mesenteric artery Heart failure Nitric oxide (NO)
topic	ddc 610 fid PHARM bkl 44.38 misc Phosphodiesterase inhibitor misc Vascular tone misc Mesenteric artery misc Heart failure misc Nitric oxide (NO)
topic_unstemmed	ddc 610 fid PHARM bkl 44.38 misc Phosphodiesterase inhibitor misc Vascular tone misc Mesenteric artery misc Heart failure misc Nitric oxide (NO)
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title	Phosphodiesterases type 2, 3 and 4 promote vascular tone in mesenteric arteries from rats with heart failure
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title_full	Phosphodiesterases type 2, 3 and 4 promote vascular tone in mesenteric arteries from rats with heart failure
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author_browse	Wang, Liting Hubert, Fabien Idres, Sarah Belacel-Ouari, Milia Domergue, Valérie Domenichini, Séverine Lefebvre, Florence Mika, Delphine Fischmeister, Rodolphe Leblais, Véronique Manoury, Boris
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title_sort	phosphodiesterases type 2, 3 and 4 promote vascular tone in mesenteric arteries from rats with heart failure
title_auth	Phosphodiesterases type 2, 3 and 4 promote vascular tone in mesenteric arteries from rats with heart failure
abstract	Phosphodiesterases (PDE) type 3 and 4 promote vasoconstriction by hydrolysing cAMP. In experimental heart failure (HF), PDE3 makes PDE4 redundant in aorta, but it is not known if this occurs in resistance vessels, such as mesenteric artery. As PDE2 is increased in the failing myocardium, its possible role in the vasculature also needs to be addressed. Here, the function of PDE2, PDE3 and PDE4 in rat mesenteric arteries was characterized in experimental HF.
abstractGer	Phosphodiesterases (PDE) type 3 and 4 promote vasoconstriction by hydrolysing cAMP. In experimental heart failure (HF), PDE3 makes PDE4 redundant in aorta, but it is not known if this occurs in resistance vessels, such as mesenteric artery. As PDE2 is increased in the failing myocardium, its possible role in the vasculature also needs to be addressed. Here, the function of PDE2, PDE3 and PDE4 in rat mesenteric arteries was characterized in experimental HF.
abstract_unstemmed	Phosphodiesterases (PDE) type 3 and 4 promote vasoconstriction by hydrolysing cAMP. In experimental heart failure (HF), PDE3 makes PDE4 redundant in aorta, but it is not known if this occurs in resistance vessels, such as mesenteric artery. As PDE2 is increased in the failing myocardium, its possible role in the vasculature also needs to be addressed. Here, the function of PDE2, PDE3 and PDE4 in rat mesenteric arteries was characterized in experimental HF.
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title_short	Phosphodiesterases type 2, 3 and 4 promote vascular tone in mesenteric arteries from rats with heart failure
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up_date	2024-07-06T22:46:05.687Z
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Phosphodiesterases type 2, 3 and 4 promote vascular tone in mesenteric arteries from rats with heart failure

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