Physiological and

Purpose: To assess the physiological and clinical effects of different rates of intravenous fluids for volume expansion of critically ill and perioperative patients.Methods: We searched PubMed, EMBASE, and Cochrane Central Register of Controlled Trials for studies comparing intravenous infusion rate...
Ausführliche Beschreibung

Gespeichert in:

Autor*in:	Alves, João Antonio Milanese [verfasserIn] Magalhães, Marcelo Rocha [verfasserIn] Zampieri, Fernando G. [verfasserIn] Veiga, Viviane C. [verfasserIn] Maia, Israel S. [verfasserIn] Cavalcanti, Alexandre Biasi [verfasserIn]

Format:	E-Artikel
Sprache:	Englisch

Erschienen:	2023

Schlagwörter:	Critically ill patients Perioperative period Intravenous infusion rate

Übergeordnetes Werk:	Enthalten in: Journal of critical care - [Amsterdam] : Elsevier, 1986, 76
Übergeordnetes Werk:	volume:76

DOI / URN:	10.1016/j.jcrc.2023.154295

Katalog-ID:	ELV010048758

Internformat


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245	1	0	\|a Physiological and
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520			\|a Purpose: To assess the physiological and clinical effects of different rates of intravenous fluids for volume expansion of critically ill and perioperative patients.Methods: We searched PubMed, EMBASE, and Cochrane Central Register of Controlled Trials for studies comparing intravenous infusion rates both in animals and studies involving healthy subjects, critically ill, and perioperative care patients of all ages.Results: Seven animal studies, eleven clinical studies and three studies including healthy volunteers were identified. Slower infusion led to lower mortality in two studies, lower blood loss in one study, better or more sustained expansion of plasma volume and less edema in three studies, but slower restoration of blood pressure in one study. Three healthy volunteer studies suggested more effective plasma expansion with slower infusion, whereas one trial with postoperative patients did not show plasma volume differences between different infusion rates. One randomized trial found increased mortality with faster infusion in septic children, whereas a randomized trial found no significant differences in critically ill adults.Conclusions: In this scoping review, most studies showed that slower intravenous infusion rates result in a more efficient intravascular expansion, with a longer effect, and less edema than faster rates. Effects on clinical outcomes were inconsistent.
650		4	\|a Critically ill patients
650		4	\|a Perioperative period
650		4	\|a Intravenous infusion rate
700	1		\|a Magalhães, Marcelo Rocha \|e verfasserin \|4 aut
700	1		\|a Zampieri, Fernando G. \|e verfasserin \|4 aut
700	1		\|a Veiga, Viviane C. \|e verfasserin \|4 aut
700	1		\|a Maia, Israel S. \|e verfasserin \|4 aut
700	1		\|a Cavalcanti, Alexandre Biasi \|e verfasserin \|4 aut
773	0	8	\|i Enthalten in \|t Journal of critical care \|d [Amsterdam] : Elsevier, 1986 \|g 76 \|h Online-Ressource \|w (DE-627)326646167 \|w (DE-600)2041640-4 \|w (DE-576)096188820 \|x 1557-8615 \|7 nnns
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912			\|a GBV_ILN_187
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912			\|a GBV_ILN_2049
912			\|a GBV_ILN_2050
912			\|a GBV_ILN_2055
912			\|a GBV_ILN_2056
912			\|a GBV_ILN_2059
912			\|a GBV_ILN_2061
912			\|a GBV_ILN_2064
912			\|a GBV_ILN_2088
912			\|a GBV_ILN_2106
912			\|a GBV_ILN_2110
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912			\|a GBV_ILN_2112
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912			\|a GBV_ILN_4325
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912			\|a GBV_ILN_4333
912			\|a GBV_ILN_4334
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936	b	k	\|a 44.69 \|j Intensivmedizin \|q VZ
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Indexfelder

author_variant	j a m a jam jama m r m mr mrm f g z fg fgz v c v vc vcv i s m is ism a b c ab abc
matchkey_str	article:15578615:2023----::hsooia
hierarchy_sort_str	2023
bklnumber	44.69
publishDate	2023
allfields	10.1016/j.jcrc.2023.154295 doi (DE-627)ELV010048758 (ELSEVIER)S0883-9441(23)00044-8 DE-627 ger DE-627 rda eng 610 VZ 44.69 bkl Alves, João Antonio Milanese verfasserin aut Physiological and 2023 nicht spezifiziert zzz rdacontent Computermedien c rdamedia Online-Ressource cr rdacarrier Purpose: To assess the physiological and clinical effects of different rates of intravenous fluids for volume expansion of critically ill and perioperative patients.Methods: We searched PubMed, EMBASE, and Cochrane Central Register of Controlled Trials for studies comparing intravenous infusion rates both in animals and studies involving healthy subjects, critically ill, and perioperative care patients of all ages.Results: Seven animal studies, eleven clinical studies and three studies including healthy volunteers were identified. Slower infusion led to lower mortality in two studies, lower blood loss in one study, better or more sustained expansion of plasma volume and less edema in three studies, but slower restoration of blood pressure in one study. Three healthy volunteer studies suggested more effective plasma expansion with slower infusion, whereas one trial with postoperative patients did not show plasma volume differences between different infusion rates. One randomized trial found increased mortality with faster infusion in septic children, whereas a randomized trial found no significant differences in critically ill adults.Conclusions: In this scoping review, most studies showed that slower intravenous infusion rates result in a more efficient intravascular expansion, with a longer effect, and less edema than faster rates. Effects on clinical outcomes were inconsistent. Critically ill patients Perioperative period Intravenous infusion rate Magalhães, Marcelo Rocha verfasserin aut Zampieri, Fernando G. verfasserin aut Veiga, Viviane C. verfasserin aut Maia, Israel S. verfasserin aut Cavalcanti, Alexandre Biasi verfasserin aut Enthalten in Journal of critical care [Amsterdam] : Elsevier, 1986 76 Online-Ressource (DE-627)326646167 (DE-600)2041640-4 (DE-576)096188820 1557-8615 nnns volume:76 GBV_USEFLAG_U GBV_ELV SYSFLAG_U SSG-OLC-PHA GBV_ILN_20 GBV_ILN_22 GBV_ILN_23 GBV_ILN_24 GBV_ILN_31 GBV_ILN_32 GBV_ILN_40 GBV_ILN_60 GBV_ILN_62 GBV_ILN_65 GBV_ILN_69 GBV_ILN_70 GBV_ILN_73 GBV_ILN_74 GBV_ILN_90 GBV_ILN_100 GBV_ILN_101 GBV_ILN_105 GBV_ILN_110 GBV_ILN_151 GBV_ILN_187 GBV_ILN_213 GBV_ILN_224 GBV_ILN_230 GBV_ILN_370 GBV_ILN_602 GBV_ILN_702 GBV_ILN_2001 GBV_ILN_2003 GBV_ILN_2004 GBV_ILN_2005 GBV_ILN_2007 GBV_ILN_2008 GBV_ILN_2009 GBV_ILN_2010 GBV_ILN_2011 GBV_ILN_2014 GBV_ILN_2015 GBV_ILN_2020 GBV_ILN_2021 GBV_ILN_2025 GBV_ILN_2026 GBV_ILN_2027 GBV_ILN_2034 GBV_ILN_2044 GBV_ILN_2048 GBV_ILN_2049 GBV_ILN_2050 GBV_ILN_2055 GBV_ILN_2056 GBV_ILN_2059 GBV_ILN_2061 GBV_ILN_2064 GBV_ILN_2088 GBV_ILN_2106 GBV_ILN_2110 GBV_ILN_2111 GBV_ILN_2112 GBV_ILN_2122 GBV_ILN_2129 GBV_ILN_2143 GBV_ILN_2152 GBV_ILN_2153 GBV_ILN_2190 GBV_ILN_2232 GBV_ILN_2336 GBV_ILN_2470 GBV_ILN_2507 GBV_ILN_4035 GBV_ILN_4037 GBV_ILN_4112 GBV_ILN_4125 GBV_ILN_4242 GBV_ILN_4249 GBV_ILN_4251 GBV_ILN_4305 GBV_ILN_4306 GBV_ILN_4307 GBV_ILN_4313 GBV_ILN_4322 GBV_ILN_4323 GBV_ILN_4324 GBV_ILN_4325 GBV_ILN_4326 GBV_ILN_4333 GBV_ILN_4334 GBV_ILN_4338 GBV_ILN_4393 GBV_ILN_4700 44.69 Intensivmedizin VZ AR 76
spelling	10.1016/j.jcrc.2023.154295 doi (DE-627)ELV010048758 (ELSEVIER)S0883-9441(23)00044-8 DE-627 ger DE-627 rda eng 610 VZ 44.69 bkl Alves, João Antonio Milanese verfasserin aut Physiological and 2023 nicht spezifiziert zzz rdacontent Computermedien c rdamedia Online-Ressource cr rdacarrier Purpose: To assess the physiological and clinical effects of different rates of intravenous fluids for volume expansion of critically ill and perioperative patients.Methods: We searched PubMed, EMBASE, and Cochrane Central Register of Controlled Trials for studies comparing intravenous infusion rates both in animals and studies involving healthy subjects, critically ill, and perioperative care patients of all ages.Results: Seven animal studies, eleven clinical studies and three studies including healthy volunteers were identified. Slower infusion led to lower mortality in two studies, lower blood loss in one study, better or more sustained expansion of plasma volume and less edema in three studies, but slower restoration of blood pressure in one study. Three healthy volunteer studies suggested more effective plasma expansion with slower infusion, whereas one trial with postoperative patients did not show plasma volume differences between different infusion rates. One randomized trial found increased mortality with faster infusion in septic children, whereas a randomized trial found no significant differences in critically ill adults.Conclusions: In this scoping review, most studies showed that slower intravenous infusion rates result in a more efficient intravascular expansion, with a longer effect, and less edema than faster rates. Effects on clinical outcomes were inconsistent. Critically ill patients Perioperative period Intravenous infusion rate Magalhães, Marcelo Rocha verfasserin aut Zampieri, Fernando G. verfasserin aut Veiga, Viviane C. verfasserin aut Maia, Israel S. verfasserin aut Cavalcanti, Alexandre Biasi verfasserin aut Enthalten in Journal of critical care [Amsterdam] : Elsevier, 1986 76 Online-Ressource (DE-627)326646167 (DE-600)2041640-4 (DE-576)096188820 1557-8615 nnns volume:76 GBV_USEFLAG_U GBV_ELV SYSFLAG_U SSG-OLC-PHA GBV_ILN_20 GBV_ILN_22 GBV_ILN_23 GBV_ILN_24 GBV_ILN_31 GBV_ILN_32 GBV_ILN_40 GBV_ILN_60 GBV_ILN_62 GBV_ILN_65 GBV_ILN_69 GBV_ILN_70 GBV_ILN_73 GBV_ILN_74 GBV_ILN_90 GBV_ILN_100 GBV_ILN_101 GBV_ILN_105 GBV_ILN_110 GBV_ILN_151 GBV_ILN_187 GBV_ILN_213 GBV_ILN_224 GBV_ILN_230 GBV_ILN_370 GBV_ILN_602 GBV_ILN_702 GBV_ILN_2001 GBV_ILN_2003 GBV_ILN_2004 GBV_ILN_2005 GBV_ILN_2007 GBV_ILN_2008 GBV_ILN_2009 GBV_ILN_2010 GBV_ILN_2011 GBV_ILN_2014 GBV_ILN_2015 GBV_ILN_2020 GBV_ILN_2021 GBV_ILN_2025 GBV_ILN_2026 GBV_ILN_2027 GBV_ILN_2034 GBV_ILN_2044 GBV_ILN_2048 GBV_ILN_2049 GBV_ILN_2050 GBV_ILN_2055 GBV_ILN_2056 GBV_ILN_2059 GBV_ILN_2061 GBV_ILN_2064 GBV_ILN_2088 GBV_ILN_2106 GBV_ILN_2110 GBV_ILN_2111 GBV_ILN_2112 GBV_ILN_2122 GBV_ILN_2129 GBV_ILN_2143 GBV_ILN_2152 GBV_ILN_2153 GBV_ILN_2190 GBV_ILN_2232 GBV_ILN_2336 GBV_ILN_2470 GBV_ILN_2507 GBV_ILN_4035 GBV_ILN_4037 GBV_ILN_4112 GBV_ILN_4125 GBV_ILN_4242 GBV_ILN_4249 GBV_ILN_4251 GBV_ILN_4305 GBV_ILN_4306 GBV_ILN_4307 GBV_ILN_4313 GBV_ILN_4322 GBV_ILN_4323 GBV_ILN_4324 GBV_ILN_4325 GBV_ILN_4326 GBV_ILN_4333 GBV_ILN_4334 GBV_ILN_4338 GBV_ILN_4393 GBV_ILN_4700 44.69 Intensivmedizin VZ AR 76
allfields_unstemmed	10.1016/j.jcrc.2023.154295 doi (DE-627)ELV010048758 (ELSEVIER)S0883-9441(23)00044-8 DE-627 ger DE-627 rda eng 610 VZ 44.69 bkl Alves, João Antonio Milanese verfasserin aut Physiological and 2023 nicht spezifiziert zzz rdacontent Computermedien c rdamedia Online-Ressource cr rdacarrier Purpose: To assess the physiological and clinical effects of different rates of intravenous fluids for volume expansion of critically ill and perioperative patients.Methods: We searched PubMed, EMBASE, and Cochrane Central Register of Controlled Trials for studies comparing intravenous infusion rates both in animals and studies involving healthy subjects, critically ill, and perioperative care patients of all ages.Results: Seven animal studies, eleven clinical studies and three studies including healthy volunteers were identified. Slower infusion led to lower mortality in two studies, lower blood loss in one study, better or more sustained expansion of plasma volume and less edema in three studies, but slower restoration of blood pressure in one study. Three healthy volunteer studies suggested more effective plasma expansion with slower infusion, whereas one trial with postoperative patients did not show plasma volume differences between different infusion rates. One randomized trial found increased mortality with faster infusion in septic children, whereas a randomized trial found no significant differences in critically ill adults.Conclusions: In this scoping review, most studies showed that slower intravenous infusion rates result in a more efficient intravascular expansion, with a longer effect, and less edema than faster rates. Effects on clinical outcomes were inconsistent. Critically ill patients Perioperative period Intravenous infusion rate Magalhães, Marcelo Rocha verfasserin aut Zampieri, Fernando G. verfasserin aut Veiga, Viviane C. verfasserin aut Maia, Israel S. verfasserin aut Cavalcanti, Alexandre Biasi verfasserin aut Enthalten in Journal of critical care [Amsterdam] : Elsevier, 1986 76 Online-Ressource (DE-627)326646167 (DE-600)2041640-4 (DE-576)096188820 1557-8615 nnns volume:76 GBV_USEFLAG_U GBV_ELV SYSFLAG_U SSG-OLC-PHA GBV_ILN_20 GBV_ILN_22 GBV_ILN_23 GBV_ILN_24 GBV_ILN_31 GBV_ILN_32 GBV_ILN_40 GBV_ILN_60 GBV_ILN_62 GBV_ILN_65 GBV_ILN_69 GBV_ILN_70 GBV_ILN_73 GBV_ILN_74 GBV_ILN_90 GBV_ILN_100 GBV_ILN_101 GBV_ILN_105 GBV_ILN_110 GBV_ILN_151 GBV_ILN_187 GBV_ILN_213 GBV_ILN_224 GBV_ILN_230 GBV_ILN_370 GBV_ILN_602 GBV_ILN_702 GBV_ILN_2001 GBV_ILN_2003 GBV_ILN_2004 GBV_ILN_2005 GBV_ILN_2007 GBV_ILN_2008 GBV_ILN_2009 GBV_ILN_2010 GBV_ILN_2011 GBV_ILN_2014 GBV_ILN_2015 GBV_ILN_2020 GBV_ILN_2021 GBV_ILN_2025 GBV_ILN_2026 GBV_ILN_2027 GBV_ILN_2034 GBV_ILN_2044 GBV_ILN_2048 GBV_ILN_2049 GBV_ILN_2050 GBV_ILN_2055 GBV_ILN_2056 GBV_ILN_2059 GBV_ILN_2061 GBV_ILN_2064 GBV_ILN_2088 GBV_ILN_2106 GBV_ILN_2110 GBV_ILN_2111 GBV_ILN_2112 GBV_ILN_2122 GBV_ILN_2129 GBV_ILN_2143 GBV_ILN_2152 GBV_ILN_2153 GBV_ILN_2190 GBV_ILN_2232 GBV_ILN_2336 GBV_ILN_2470 GBV_ILN_2507 GBV_ILN_4035 GBV_ILN_4037 GBV_ILN_4112 GBV_ILN_4125 GBV_ILN_4242 GBV_ILN_4249 GBV_ILN_4251 GBV_ILN_4305 GBV_ILN_4306 GBV_ILN_4307 GBV_ILN_4313 GBV_ILN_4322 GBV_ILN_4323 GBV_ILN_4324 GBV_ILN_4325 GBV_ILN_4326 GBV_ILN_4333 GBV_ILN_4334 GBV_ILN_4338 GBV_ILN_4393 GBV_ILN_4700 44.69 Intensivmedizin VZ AR 76
allfieldsGer	10.1016/j.jcrc.2023.154295 doi (DE-627)ELV010048758 (ELSEVIER)S0883-9441(23)00044-8 DE-627 ger DE-627 rda eng 610 VZ 44.69 bkl Alves, João Antonio Milanese verfasserin aut Physiological and 2023 nicht spezifiziert zzz rdacontent Computermedien c rdamedia Online-Ressource cr rdacarrier Purpose: To assess the physiological and clinical effects of different rates of intravenous fluids for volume expansion of critically ill and perioperative patients.Methods: We searched PubMed, EMBASE, and Cochrane Central Register of Controlled Trials for studies comparing intravenous infusion rates both in animals and studies involving healthy subjects, critically ill, and perioperative care patients of all ages.Results: Seven animal studies, eleven clinical studies and three studies including healthy volunteers were identified. Slower infusion led to lower mortality in two studies, lower blood loss in one study, better or more sustained expansion of plasma volume and less edema in three studies, but slower restoration of blood pressure in one study. Three healthy volunteer studies suggested more effective plasma expansion with slower infusion, whereas one trial with postoperative patients did not show plasma volume differences between different infusion rates. One randomized trial found increased mortality with faster infusion in septic children, whereas a randomized trial found no significant differences in critically ill adults.Conclusions: In this scoping review, most studies showed that slower intravenous infusion rates result in a more efficient intravascular expansion, with a longer effect, and less edema than faster rates. Effects on clinical outcomes were inconsistent. Critically ill patients Perioperative period Intravenous infusion rate Magalhães, Marcelo Rocha verfasserin aut Zampieri, Fernando G. verfasserin aut Veiga, Viviane C. verfasserin aut Maia, Israel S. verfasserin aut Cavalcanti, Alexandre Biasi verfasserin aut Enthalten in Journal of critical care [Amsterdam] : Elsevier, 1986 76 Online-Ressource (DE-627)326646167 (DE-600)2041640-4 (DE-576)096188820 1557-8615 nnns volume:76 GBV_USEFLAG_U GBV_ELV SYSFLAG_U SSG-OLC-PHA GBV_ILN_20 GBV_ILN_22 GBV_ILN_23 GBV_ILN_24 GBV_ILN_31 GBV_ILN_32 GBV_ILN_40 GBV_ILN_60 GBV_ILN_62 GBV_ILN_65 GBV_ILN_69 GBV_ILN_70 GBV_ILN_73 GBV_ILN_74 GBV_ILN_90 GBV_ILN_100 GBV_ILN_101 GBV_ILN_105 GBV_ILN_110 GBV_ILN_151 GBV_ILN_187 GBV_ILN_213 GBV_ILN_224 GBV_ILN_230 GBV_ILN_370 GBV_ILN_602 GBV_ILN_702 GBV_ILN_2001 GBV_ILN_2003 GBV_ILN_2004 GBV_ILN_2005 GBV_ILN_2007 GBV_ILN_2008 GBV_ILN_2009 GBV_ILN_2010 GBV_ILN_2011 GBV_ILN_2014 GBV_ILN_2015 GBV_ILN_2020 GBV_ILN_2021 GBV_ILN_2025 GBV_ILN_2026 GBV_ILN_2027 GBV_ILN_2034 GBV_ILN_2044 GBV_ILN_2048 GBV_ILN_2049 GBV_ILN_2050 GBV_ILN_2055 GBV_ILN_2056 GBV_ILN_2059 GBV_ILN_2061 GBV_ILN_2064 GBV_ILN_2088 GBV_ILN_2106 GBV_ILN_2110 GBV_ILN_2111 GBV_ILN_2112 GBV_ILN_2122 GBV_ILN_2129 GBV_ILN_2143 GBV_ILN_2152 GBV_ILN_2153 GBV_ILN_2190 GBV_ILN_2232 GBV_ILN_2336 GBV_ILN_2470 GBV_ILN_2507 GBV_ILN_4035 GBV_ILN_4037 GBV_ILN_4112 GBV_ILN_4125 GBV_ILN_4242 GBV_ILN_4249 GBV_ILN_4251 GBV_ILN_4305 GBV_ILN_4306 GBV_ILN_4307 GBV_ILN_4313 GBV_ILN_4322 GBV_ILN_4323 GBV_ILN_4324 GBV_ILN_4325 GBV_ILN_4326 GBV_ILN_4333 GBV_ILN_4334 GBV_ILN_4338 GBV_ILN_4393 GBV_ILN_4700 44.69 Intensivmedizin VZ AR 76
allfieldsSound	10.1016/j.jcrc.2023.154295 doi (DE-627)ELV010048758 (ELSEVIER)S0883-9441(23)00044-8 DE-627 ger DE-627 rda eng 610 VZ 44.69 bkl Alves, João Antonio Milanese verfasserin aut Physiological and 2023 nicht spezifiziert zzz rdacontent Computermedien c rdamedia Online-Ressource cr rdacarrier Purpose: To assess the physiological and clinical effects of different rates of intravenous fluids for volume expansion of critically ill and perioperative patients.Methods: We searched PubMed, EMBASE, and Cochrane Central Register of Controlled Trials for studies comparing intravenous infusion rates both in animals and studies involving healthy subjects, critically ill, and perioperative care patients of all ages.Results: Seven animal studies, eleven clinical studies and three studies including healthy volunteers were identified. Slower infusion led to lower mortality in two studies, lower blood loss in one study, better or more sustained expansion of plasma volume and less edema in three studies, but slower restoration of blood pressure in one study. Three healthy volunteer studies suggested more effective plasma expansion with slower infusion, whereas one trial with postoperative patients did not show plasma volume differences between different infusion rates. One randomized trial found increased mortality with faster infusion in septic children, whereas a randomized trial found no significant differences in critically ill adults.Conclusions: In this scoping review, most studies showed that slower intravenous infusion rates result in a more efficient intravascular expansion, with a longer effect, and less edema than faster rates. Effects on clinical outcomes were inconsistent. Critically ill patients Perioperative period Intravenous infusion rate Magalhães, Marcelo Rocha verfasserin aut Zampieri, Fernando G. verfasserin aut Veiga, Viviane C. verfasserin aut Maia, Israel S. verfasserin aut Cavalcanti, Alexandre Biasi verfasserin aut Enthalten in Journal of critical care [Amsterdam] : Elsevier, 1986 76 Online-Ressource (DE-627)326646167 (DE-600)2041640-4 (DE-576)096188820 1557-8615 nnns volume:76 GBV_USEFLAG_U GBV_ELV SYSFLAG_U SSG-OLC-PHA GBV_ILN_20 GBV_ILN_22 GBV_ILN_23 GBV_ILN_24 GBV_ILN_31 GBV_ILN_32 GBV_ILN_40 GBV_ILN_60 GBV_ILN_62 GBV_ILN_65 GBV_ILN_69 GBV_ILN_70 GBV_ILN_73 GBV_ILN_74 GBV_ILN_90 GBV_ILN_100 GBV_ILN_101 GBV_ILN_105 GBV_ILN_110 GBV_ILN_151 GBV_ILN_187 GBV_ILN_213 GBV_ILN_224 GBV_ILN_230 GBV_ILN_370 GBV_ILN_602 GBV_ILN_702 GBV_ILN_2001 GBV_ILN_2003 GBV_ILN_2004 GBV_ILN_2005 GBV_ILN_2007 GBV_ILN_2008 GBV_ILN_2009 GBV_ILN_2010 GBV_ILN_2011 GBV_ILN_2014 GBV_ILN_2015 GBV_ILN_2020 GBV_ILN_2021 GBV_ILN_2025 GBV_ILN_2026 GBV_ILN_2027 GBV_ILN_2034 GBV_ILN_2044 GBV_ILN_2048 GBV_ILN_2049 GBV_ILN_2050 GBV_ILN_2055 GBV_ILN_2056 GBV_ILN_2059 GBV_ILN_2061 GBV_ILN_2064 GBV_ILN_2088 GBV_ILN_2106 GBV_ILN_2110 GBV_ILN_2111 GBV_ILN_2112 GBV_ILN_2122 GBV_ILN_2129 GBV_ILN_2143 GBV_ILN_2152 GBV_ILN_2153 GBV_ILN_2190 GBV_ILN_2232 GBV_ILN_2336 GBV_ILN_2470 GBV_ILN_2507 GBV_ILN_4035 GBV_ILN_4037 GBV_ILN_4112 GBV_ILN_4125 GBV_ILN_4242 GBV_ILN_4249 GBV_ILN_4251 GBV_ILN_4305 GBV_ILN_4306 GBV_ILN_4307 GBV_ILN_4313 GBV_ILN_4322 GBV_ILN_4323 GBV_ILN_4324 GBV_ILN_4325 GBV_ILN_4326 GBV_ILN_4333 GBV_ILN_4334 GBV_ILN_4338 GBV_ILN_4393 GBV_ILN_4700 44.69 Intensivmedizin VZ AR 76
language	English
source	Enthalten in Journal of critical care 76 volume:76
sourceStr	Enthalten in Journal of critical care 76 volume:76
format_phy_str_mv	Article
bklname	Intensivmedizin
institution	findex.gbv.de
topic_facet	Critically ill patients Perioperative period Intravenous infusion rate
dewey-raw	610
isfreeaccess_bool	false
container_title	Journal of critical care
authorswithroles_txt_mv	Alves, João Antonio Milanese @@aut@@ Magalhães, Marcelo Rocha @@aut@@ Zampieri, Fernando G. @@aut@@ Veiga, Viviane C. @@aut@@ Maia, Israel S. @@aut@@ Cavalcanti, Alexandre Biasi @@aut@@
publishDateDaySort_date	2023-01-01T00:00:00Z
hierarchy_top_id	326646167
dewey-sort	3610
id	ELV010048758
language_de	englisch
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author	Alves, João Antonio Milanese
spellingShingle	Alves, João Antonio Milanese ddc 610 bkl 44.69 misc Critically ill patients misc Perioperative period misc Intravenous infusion rate Physiological and
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topic_title	610 VZ 44.69 bkl Physiological and Critically ill patients Perioperative period Intravenous infusion rate
topic	ddc 610 bkl 44.69 misc Critically ill patients misc Perioperative period misc Intravenous infusion rate
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author_browse	Alves, João Antonio Milanese Magalhães, Marcelo Rocha Zampieri, Fernando G. Veiga, Viviane C. Maia, Israel S. Cavalcanti, Alexandre Biasi
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title_sort	physiological and
title_auth	Physiological and
abstract	Purpose: To assess the physiological and clinical effects of different rates of intravenous fluids for volume expansion of critically ill and perioperative patients.Methods: We searched PubMed, EMBASE, and Cochrane Central Register of Controlled Trials for studies comparing intravenous infusion rates both in animals and studies involving healthy subjects, critically ill, and perioperative care patients of all ages.Results: Seven animal studies, eleven clinical studies and three studies including healthy volunteers were identified. Slower infusion led to lower mortality in two studies, lower blood loss in one study, better or more sustained expansion of plasma volume and less edema in three studies, but slower restoration of blood pressure in one study. Three healthy volunteer studies suggested more effective plasma expansion with slower infusion, whereas one trial with postoperative patients did not show plasma volume differences between different infusion rates. One randomized trial found increased mortality with faster infusion in septic children, whereas a randomized trial found no significant differences in critically ill adults.Conclusions: In this scoping review, most studies showed that slower intravenous infusion rates result in a more efficient intravascular expansion, with a longer effect, and less edema than faster rates. Effects on clinical outcomes were inconsistent.
abstractGer	Purpose: To assess the physiological and clinical effects of different rates of intravenous fluids for volume expansion of critically ill and perioperative patients.Methods: We searched PubMed, EMBASE, and Cochrane Central Register of Controlled Trials for studies comparing intravenous infusion rates both in animals and studies involving healthy subjects, critically ill, and perioperative care patients of all ages.Results: Seven animal studies, eleven clinical studies and three studies including healthy volunteers were identified. Slower infusion led to lower mortality in two studies, lower blood loss in one study, better or more sustained expansion of plasma volume and less edema in three studies, but slower restoration of blood pressure in one study. Three healthy volunteer studies suggested more effective plasma expansion with slower infusion, whereas one trial with postoperative patients did not show plasma volume differences between different infusion rates. One randomized trial found increased mortality with faster infusion in septic children, whereas a randomized trial found no significant differences in critically ill adults.Conclusions: In this scoping review, most studies showed that slower intravenous infusion rates result in a more efficient intravascular expansion, with a longer effect, and less edema than faster rates. Effects on clinical outcomes were inconsistent.
abstract_unstemmed	Purpose: To assess the physiological and clinical effects of different rates of intravenous fluids for volume expansion of critically ill and perioperative patients.Methods: We searched PubMed, EMBASE, and Cochrane Central Register of Controlled Trials for studies comparing intravenous infusion rates both in animals and studies involving healthy subjects, critically ill, and perioperative care patients of all ages.Results: Seven animal studies, eleven clinical studies and three studies including healthy volunteers were identified. Slower infusion led to lower mortality in two studies, lower blood loss in one study, better or more sustained expansion of plasma volume and less edema in three studies, but slower restoration of blood pressure in one study. Three healthy volunteer studies suggested more effective plasma expansion with slower infusion, whereas one trial with postoperative patients did not show plasma volume differences between different infusion rates. One randomized trial found increased mortality with faster infusion in septic children, whereas a randomized trial found no significant differences in critically ill adults.Conclusions: In this scoping review, most studies showed that slower intravenous infusion rates result in a more efficient intravascular expansion, with a longer effect, and less edema than faster rates. Effects on clinical outcomes were inconsistent.
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title_short	Physiological and
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author2	Magalhães, Marcelo Rocha Zampieri, Fernando G. Veiga, Viviane C. Maia, Israel S. Cavalcanti, Alexandre Biasi
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up_date	2024-07-06T16:38:45.656Z
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