Ratiometric upconversion-luminescence in-situ sampling aptasensing platform integrated with smartphone-based device for visual detection of 17β-estradiol

Rapid initial screening of health markers and food hazards are crucial indicators for ensuring human well-being. Hence, an upconversion-luminescence based aptasensing platform for the in-situ sampling of hazards has been proposed with portable equipment for point-of-care testing (POCT). The aptasens...
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Autor*in:	Wu, Jizhong [verfasserIn] Ahmad, Waqas [verfasserIn] Zhang, Jingui [verfasserIn] Wei, Wenya [verfasserIn] Yu, Jinghao [verfasserIn] Zhang, Wenqian [verfasserIn] Chen, Quansheng [verfasserIn] Ouyang, Qin [verfasserIn]

Format:	E-Artikel
Sprache:	Englisch

Erschienen:	2023

Schlagwörter:	17β-Estradiol Point-of-care testing Paper-based microfluidic devices Upconversion nanoparticles Smartphone imaging

Übergeordnetes Werk:	Enthalten in: Sensors and actuators / B - Amsterdam [u.a.] : Elsevier Science, 1990, 390
Übergeordnetes Werk:	volume:390

DOI / URN:	10.1016/j.snb.2023.133999

Katalog-ID:	ELV010204903

Internformat


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520			\|a Rapid initial screening of health markers and food hazards are crucial indicators for ensuring human well-being. Hence, an upconversion-luminescence based aptasensing platform for the in-situ sampling of hazards has been proposed with portable equipment for point-of-care testing (POCT). The aptasensing platform consists of a polymethylmethacrylate needle and a paper-based microfluidic strip patterned with a sacrificial valve, paraffin barriers, and three independent detection zones. The detection zones were assembled with a luminescence resonance energy transfer system constructed by the core/shell/shell structure of upconversion nanoparticles (UCNPs) as the donor, SYBR Green Ⅰ as the acceptor with an aptamer bridge. The biosensing platform has been extended for 17β-estradiol to validate its feasibility in a dual-mode signal readout system based on smartphone imaging and spectrometer. Under the optimal conditions, good linear relationships were achieved based on images (0.05–200 ng/mL) and ratiometric spectra (0.02–200 ng/mL), respectively. Thus, the biosensing platform with portable equipment might provide an economic and viable route for POCT.
650		4	\|a 17β-Estradiol
650		4	\|a Point-of-care testing
650		4	\|a Paper-based microfluidic devices
650		4	\|a Upconversion nanoparticles
650		4	\|a Smartphone imaging
700	1		\|a Ahmad, Waqas \|e verfasserin \|4 aut
700	1		\|a Zhang, Jingui \|e verfasserin \|4 aut
700	1		\|a Wei, Wenya \|e verfasserin \|4 aut
700	1		\|a Yu, Jinghao \|e verfasserin \|4 aut
700	1		\|a Zhang, Wenqian \|e verfasserin \|4 aut
700	1		\|a Chen, Quansheng \|e verfasserin \|4 aut
700	1		\|a Ouyang, Qin \|e verfasserin \|4 aut
773	0	8	\|i Enthalten in \|t Sensors and actuators <Lausanne> / B \|d Amsterdam [u.a.] : Elsevier Science, 1990 \|g 390 \|h Online-Ressource \|w (DE-627)306710358 \|w (DE-600)1500731-5 \|w (DE-576)082435855 \|x 0925-4005 \|7 nnns
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912			\|a GBV_ILN_2044
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912			\|a GBV_ILN_2049
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allfields	10.1016/j.snb.2023.133999 doi (DE-627)ELV010204903 (ELSEVIER)S0925-4005(23)00714-1 DE-627 ger DE-627 rda eng 530 620 VZ 50.22 bkl 35.07 bkl Wu, Jizhong verfasserin aut Ratiometric upconversion-luminescence in-situ sampling aptasensing platform integrated with smartphone-based device for visual detection of 17β-estradiol 2023 nicht spezifiziert zzz rdacontent Computermedien c rdamedia Online-Ressource cr rdacarrier Rapid initial screening of health markers and food hazards are crucial indicators for ensuring human well-being. Hence, an upconversion-luminescence based aptasensing platform for the in-situ sampling of hazards has been proposed with portable equipment for point-of-care testing (POCT). The aptasensing platform consists of a polymethylmethacrylate needle and a paper-based microfluidic strip patterned with a sacrificial valve, paraffin barriers, and three independent detection zones. The detection zones were assembled with a luminescence resonance energy transfer system constructed by the core/shell/shell structure of upconversion nanoparticles (UCNPs) as the donor, SYBR Green Ⅰ as the acceptor with an aptamer bridge. The biosensing platform has been extended for 17β-estradiol to validate its feasibility in a dual-mode signal readout system based on smartphone imaging and spectrometer. Under the optimal conditions, good linear relationships were achieved based on images (0.05–200 ng/mL) and ratiometric spectra (0.02–200 ng/mL), respectively. Thus, the biosensing platform with portable equipment might provide an economic and viable route for POCT. 17β-Estradiol Point-of-care testing Paper-based microfluidic devices Upconversion nanoparticles Smartphone imaging Ahmad, Waqas verfasserin aut Zhang, Jingui verfasserin aut Wei, Wenya verfasserin aut Yu, Jinghao verfasserin aut Zhang, Wenqian verfasserin aut Chen, Quansheng verfasserin aut Ouyang, Qin verfasserin aut Enthalten in Sensors and actuators <Lausanne> / B Amsterdam [u.a.] : Elsevier Science, 1990 390 Online-Ressource (DE-627)306710358 (DE-600)1500731-5 (DE-576)082435855 0925-4005 nnns volume:390 GBV_USEFLAG_U GBV_ELV SYSFLAG_U SSG-OLC-PHA GBV_ILN_20 GBV_ILN_22 GBV_ILN_23 GBV_ILN_24 GBV_ILN_31 GBV_ILN_32 GBV_ILN_40 GBV_ILN_60 GBV_ILN_62 GBV_ILN_65 GBV_ILN_69 GBV_ILN_70 GBV_ILN_73 GBV_ILN_74 GBV_ILN_90 GBV_ILN_95 GBV_ILN_100 GBV_ILN_101 GBV_ILN_105 GBV_ILN_110 GBV_ILN_150 GBV_ILN_151 GBV_ILN_187 GBV_ILN_213 GBV_ILN_224 GBV_ILN_230 GBV_ILN_370 GBV_ILN_602 GBV_ILN_702 GBV_ILN_2001 GBV_ILN_2003 GBV_ILN_2004 GBV_ILN_2005 GBV_ILN_2007 GBV_ILN_2009 GBV_ILN_2010 GBV_ILN_2011 GBV_ILN_2014 GBV_ILN_2015 GBV_ILN_2020 GBV_ILN_2021 GBV_ILN_2025 GBV_ILN_2026 GBV_ILN_2027 GBV_ILN_2034 GBV_ILN_2044 GBV_ILN_2048 GBV_ILN_2049 GBV_ILN_2050 GBV_ILN_2055 GBV_ILN_2056 GBV_ILN_2059 GBV_ILN_2061 GBV_ILN_2064 GBV_ILN_2106 GBV_ILN_2110 GBV_ILN_2111 GBV_ILN_2112 GBV_ILN_2122 GBV_ILN_2129 GBV_ILN_2143 GBV_ILN_2152 GBV_ILN_2153 GBV_ILN_2190 GBV_ILN_2232 GBV_ILN_2336 GBV_ILN_2470 GBV_ILN_2507 GBV_ILN_4035 GBV_ILN_4037 GBV_ILN_4112 GBV_ILN_4125 GBV_ILN_4242 GBV_ILN_4249 GBV_ILN_4251 GBV_ILN_4305 GBV_ILN_4306 GBV_ILN_4307 GBV_ILN_4313 GBV_ILN_4322 GBV_ILN_4323 GBV_ILN_4324 GBV_ILN_4326 GBV_ILN_4333 GBV_ILN_4334 GBV_ILN_4338 GBV_ILN_4393 GBV_ILN_4700 50.22 Sensorik VZ 35.07 Chemisches Labor chemische Methoden VZ AR 390
spelling	10.1016/j.snb.2023.133999 doi (DE-627)ELV010204903 (ELSEVIER)S0925-4005(23)00714-1 DE-627 ger DE-627 rda eng 530 620 VZ 50.22 bkl 35.07 bkl Wu, Jizhong verfasserin aut Ratiometric upconversion-luminescence in-situ sampling aptasensing platform integrated with smartphone-based device for visual detection of 17β-estradiol 2023 nicht spezifiziert zzz rdacontent Computermedien c rdamedia Online-Ressource cr rdacarrier Rapid initial screening of health markers and food hazards are crucial indicators for ensuring human well-being. Hence, an upconversion-luminescence based aptasensing platform for the in-situ sampling of hazards has been proposed with portable equipment for point-of-care testing (POCT). The aptasensing platform consists of a polymethylmethacrylate needle and a paper-based microfluidic strip patterned with a sacrificial valve, paraffin barriers, and three independent detection zones. The detection zones were assembled with a luminescence resonance energy transfer system constructed by the core/shell/shell structure of upconversion nanoparticles (UCNPs) as the donor, SYBR Green Ⅰ as the acceptor with an aptamer bridge. The biosensing platform has been extended for 17β-estradiol to validate its feasibility in a dual-mode signal readout system based on smartphone imaging and spectrometer. Under the optimal conditions, good linear relationships were achieved based on images (0.05–200 ng/mL) and ratiometric spectra (0.02–200 ng/mL), respectively. Thus, the biosensing platform with portable equipment might provide an economic and viable route for POCT. 17β-Estradiol Point-of-care testing Paper-based microfluidic devices Upconversion nanoparticles Smartphone imaging Ahmad, Waqas verfasserin aut Zhang, Jingui verfasserin aut Wei, Wenya verfasserin aut Yu, Jinghao verfasserin aut Zhang, Wenqian verfasserin aut Chen, Quansheng verfasserin aut Ouyang, Qin verfasserin aut Enthalten in Sensors and actuators <Lausanne> / B Amsterdam [u.a.] : Elsevier Science, 1990 390 Online-Ressource (DE-627)306710358 (DE-600)1500731-5 (DE-576)082435855 0925-4005 nnns volume:390 GBV_USEFLAG_U GBV_ELV SYSFLAG_U SSG-OLC-PHA GBV_ILN_20 GBV_ILN_22 GBV_ILN_23 GBV_ILN_24 GBV_ILN_31 GBV_ILN_32 GBV_ILN_40 GBV_ILN_60 GBV_ILN_62 GBV_ILN_65 GBV_ILN_69 GBV_ILN_70 GBV_ILN_73 GBV_ILN_74 GBV_ILN_90 GBV_ILN_95 GBV_ILN_100 GBV_ILN_101 GBV_ILN_105 GBV_ILN_110 GBV_ILN_150 GBV_ILN_151 GBV_ILN_187 GBV_ILN_213 GBV_ILN_224 GBV_ILN_230 GBV_ILN_370 GBV_ILN_602 GBV_ILN_702 GBV_ILN_2001 GBV_ILN_2003 GBV_ILN_2004 GBV_ILN_2005 GBV_ILN_2007 GBV_ILN_2009 GBV_ILN_2010 GBV_ILN_2011 GBV_ILN_2014 GBV_ILN_2015 GBV_ILN_2020 GBV_ILN_2021 GBV_ILN_2025 GBV_ILN_2026 GBV_ILN_2027 GBV_ILN_2034 GBV_ILN_2044 GBV_ILN_2048 GBV_ILN_2049 GBV_ILN_2050 GBV_ILN_2055 GBV_ILN_2056 GBV_ILN_2059 GBV_ILN_2061 GBV_ILN_2064 GBV_ILN_2106 GBV_ILN_2110 GBV_ILN_2111 GBV_ILN_2112 GBV_ILN_2122 GBV_ILN_2129 GBV_ILN_2143 GBV_ILN_2152 GBV_ILN_2153 GBV_ILN_2190 GBV_ILN_2232 GBV_ILN_2336 GBV_ILN_2470 GBV_ILN_2507 GBV_ILN_4035 GBV_ILN_4037 GBV_ILN_4112 GBV_ILN_4125 GBV_ILN_4242 GBV_ILN_4249 GBV_ILN_4251 GBV_ILN_4305 GBV_ILN_4306 GBV_ILN_4307 GBV_ILN_4313 GBV_ILN_4322 GBV_ILN_4323 GBV_ILN_4324 GBV_ILN_4326 GBV_ILN_4333 GBV_ILN_4334 GBV_ILN_4338 GBV_ILN_4393 GBV_ILN_4700 50.22 Sensorik VZ 35.07 Chemisches Labor chemische Methoden VZ AR 390
allfields_unstemmed	10.1016/j.snb.2023.133999 doi (DE-627)ELV010204903 (ELSEVIER)S0925-4005(23)00714-1 DE-627 ger DE-627 rda eng 530 620 VZ 50.22 bkl 35.07 bkl Wu, Jizhong verfasserin aut Ratiometric upconversion-luminescence in-situ sampling aptasensing platform integrated with smartphone-based device for visual detection of 17β-estradiol 2023 nicht spezifiziert zzz rdacontent Computermedien c rdamedia Online-Ressource cr rdacarrier Rapid initial screening of health markers and food hazards are crucial indicators for ensuring human well-being. Hence, an upconversion-luminescence based aptasensing platform for the in-situ sampling of hazards has been proposed with portable equipment for point-of-care testing (POCT). The aptasensing platform consists of a polymethylmethacrylate needle and a paper-based microfluidic strip patterned with a sacrificial valve, paraffin barriers, and three independent detection zones. The detection zones were assembled with a luminescence resonance energy transfer system constructed by the core/shell/shell structure of upconversion nanoparticles (UCNPs) as the donor, SYBR Green Ⅰ as the acceptor with an aptamer bridge. The biosensing platform has been extended for 17β-estradiol to validate its feasibility in a dual-mode signal readout system based on smartphone imaging and spectrometer. Under the optimal conditions, good linear relationships were achieved based on images (0.05–200 ng/mL) and ratiometric spectra (0.02–200 ng/mL), respectively. Thus, the biosensing platform with portable equipment might provide an economic and viable route for POCT. 17β-Estradiol Point-of-care testing Paper-based microfluidic devices Upconversion nanoparticles Smartphone imaging Ahmad, Waqas verfasserin aut Zhang, Jingui verfasserin aut Wei, Wenya verfasserin aut Yu, Jinghao verfasserin aut Zhang, Wenqian verfasserin aut Chen, Quansheng verfasserin aut Ouyang, Qin verfasserin aut Enthalten in Sensors and actuators <Lausanne> / B Amsterdam [u.a.] : Elsevier Science, 1990 390 Online-Ressource (DE-627)306710358 (DE-600)1500731-5 (DE-576)082435855 0925-4005 nnns volume:390 GBV_USEFLAG_U GBV_ELV SYSFLAG_U SSG-OLC-PHA GBV_ILN_20 GBV_ILN_22 GBV_ILN_23 GBV_ILN_24 GBV_ILN_31 GBV_ILN_32 GBV_ILN_40 GBV_ILN_60 GBV_ILN_62 GBV_ILN_65 GBV_ILN_69 GBV_ILN_70 GBV_ILN_73 GBV_ILN_74 GBV_ILN_90 GBV_ILN_95 GBV_ILN_100 GBV_ILN_101 GBV_ILN_105 GBV_ILN_110 GBV_ILN_150 GBV_ILN_151 GBV_ILN_187 GBV_ILN_213 GBV_ILN_224 GBV_ILN_230 GBV_ILN_370 GBV_ILN_602 GBV_ILN_702 GBV_ILN_2001 GBV_ILN_2003 GBV_ILN_2004 GBV_ILN_2005 GBV_ILN_2007 GBV_ILN_2009 GBV_ILN_2010 GBV_ILN_2011 GBV_ILN_2014 GBV_ILN_2015 GBV_ILN_2020 GBV_ILN_2021 GBV_ILN_2025 GBV_ILN_2026 GBV_ILN_2027 GBV_ILN_2034 GBV_ILN_2044 GBV_ILN_2048 GBV_ILN_2049 GBV_ILN_2050 GBV_ILN_2055 GBV_ILN_2056 GBV_ILN_2059 GBV_ILN_2061 GBV_ILN_2064 GBV_ILN_2106 GBV_ILN_2110 GBV_ILN_2111 GBV_ILN_2112 GBV_ILN_2122 GBV_ILN_2129 GBV_ILN_2143 GBV_ILN_2152 GBV_ILN_2153 GBV_ILN_2190 GBV_ILN_2232 GBV_ILN_2336 GBV_ILN_2470 GBV_ILN_2507 GBV_ILN_4035 GBV_ILN_4037 GBV_ILN_4112 GBV_ILN_4125 GBV_ILN_4242 GBV_ILN_4249 GBV_ILN_4251 GBV_ILN_4305 GBV_ILN_4306 GBV_ILN_4307 GBV_ILN_4313 GBV_ILN_4322 GBV_ILN_4323 GBV_ILN_4324 GBV_ILN_4326 GBV_ILN_4333 GBV_ILN_4334 GBV_ILN_4338 GBV_ILN_4393 GBV_ILN_4700 50.22 Sensorik VZ 35.07 Chemisches Labor chemische Methoden VZ AR 390
allfieldsGer	10.1016/j.snb.2023.133999 doi (DE-627)ELV010204903 (ELSEVIER)S0925-4005(23)00714-1 DE-627 ger DE-627 rda eng 530 620 VZ 50.22 bkl 35.07 bkl Wu, Jizhong verfasserin aut Ratiometric upconversion-luminescence in-situ sampling aptasensing platform integrated with smartphone-based device for visual detection of 17β-estradiol 2023 nicht spezifiziert zzz rdacontent Computermedien c rdamedia Online-Ressource cr rdacarrier Rapid initial screening of health markers and food hazards are crucial indicators for ensuring human well-being. Hence, an upconversion-luminescence based aptasensing platform for the in-situ sampling of hazards has been proposed with portable equipment for point-of-care testing (POCT). The aptasensing platform consists of a polymethylmethacrylate needle and a paper-based microfluidic strip patterned with a sacrificial valve, paraffin barriers, and three independent detection zones. The detection zones were assembled with a luminescence resonance energy transfer system constructed by the core/shell/shell structure of upconversion nanoparticles (UCNPs) as the donor, SYBR Green Ⅰ as the acceptor with an aptamer bridge. The biosensing platform has been extended for 17β-estradiol to validate its feasibility in a dual-mode signal readout system based on smartphone imaging and spectrometer. Under the optimal conditions, good linear relationships were achieved based on images (0.05–200 ng/mL) and ratiometric spectra (0.02–200 ng/mL), respectively. Thus, the biosensing platform with portable equipment might provide an economic and viable route for POCT. 17β-Estradiol Point-of-care testing Paper-based microfluidic devices Upconversion nanoparticles Smartphone imaging Ahmad, Waqas verfasserin aut Zhang, Jingui verfasserin aut Wei, Wenya verfasserin aut Yu, Jinghao verfasserin aut Zhang, Wenqian verfasserin aut Chen, Quansheng verfasserin aut Ouyang, Qin verfasserin aut Enthalten in Sensors and actuators <Lausanne> / B Amsterdam [u.a.] : Elsevier Science, 1990 390 Online-Ressource (DE-627)306710358 (DE-600)1500731-5 (DE-576)082435855 0925-4005 nnns volume:390 GBV_USEFLAG_U GBV_ELV SYSFLAG_U SSG-OLC-PHA GBV_ILN_20 GBV_ILN_22 GBV_ILN_23 GBV_ILN_24 GBV_ILN_31 GBV_ILN_32 GBV_ILN_40 GBV_ILN_60 GBV_ILN_62 GBV_ILN_65 GBV_ILN_69 GBV_ILN_70 GBV_ILN_73 GBV_ILN_74 GBV_ILN_90 GBV_ILN_95 GBV_ILN_100 GBV_ILN_101 GBV_ILN_105 GBV_ILN_110 GBV_ILN_150 GBV_ILN_151 GBV_ILN_187 GBV_ILN_213 GBV_ILN_224 GBV_ILN_230 GBV_ILN_370 GBV_ILN_602 GBV_ILN_702 GBV_ILN_2001 GBV_ILN_2003 GBV_ILN_2004 GBV_ILN_2005 GBV_ILN_2007 GBV_ILN_2009 GBV_ILN_2010 GBV_ILN_2011 GBV_ILN_2014 GBV_ILN_2015 GBV_ILN_2020 GBV_ILN_2021 GBV_ILN_2025 GBV_ILN_2026 GBV_ILN_2027 GBV_ILN_2034 GBV_ILN_2044 GBV_ILN_2048 GBV_ILN_2049 GBV_ILN_2050 GBV_ILN_2055 GBV_ILN_2056 GBV_ILN_2059 GBV_ILN_2061 GBV_ILN_2064 GBV_ILN_2106 GBV_ILN_2110 GBV_ILN_2111 GBV_ILN_2112 GBV_ILN_2122 GBV_ILN_2129 GBV_ILN_2143 GBV_ILN_2152 GBV_ILN_2153 GBV_ILN_2190 GBV_ILN_2232 GBV_ILN_2336 GBV_ILN_2470 GBV_ILN_2507 GBV_ILN_4035 GBV_ILN_4037 GBV_ILN_4112 GBV_ILN_4125 GBV_ILN_4242 GBV_ILN_4249 GBV_ILN_4251 GBV_ILN_4305 GBV_ILN_4306 GBV_ILN_4307 GBV_ILN_4313 GBV_ILN_4322 GBV_ILN_4323 GBV_ILN_4324 GBV_ILN_4326 GBV_ILN_4333 GBV_ILN_4334 GBV_ILN_4338 GBV_ILN_4393 GBV_ILN_4700 50.22 Sensorik VZ 35.07 Chemisches Labor chemische Methoden VZ AR 390
allfieldsSound	10.1016/j.snb.2023.133999 doi (DE-627)ELV010204903 (ELSEVIER)S0925-4005(23)00714-1 DE-627 ger DE-627 rda eng 530 620 VZ 50.22 bkl 35.07 bkl Wu, Jizhong verfasserin aut Ratiometric upconversion-luminescence in-situ sampling aptasensing platform integrated with smartphone-based device for visual detection of 17β-estradiol 2023 nicht spezifiziert zzz rdacontent Computermedien c rdamedia Online-Ressource cr rdacarrier Rapid initial screening of health markers and food hazards are crucial indicators for ensuring human well-being. Hence, an upconversion-luminescence based aptasensing platform for the in-situ sampling of hazards has been proposed with portable equipment for point-of-care testing (POCT). The aptasensing platform consists of a polymethylmethacrylate needle and a paper-based microfluidic strip patterned with a sacrificial valve, paraffin barriers, and three independent detection zones. The detection zones were assembled with a luminescence resonance energy transfer system constructed by the core/shell/shell structure of upconversion nanoparticles (UCNPs) as the donor, SYBR Green Ⅰ as the acceptor with an aptamer bridge. The biosensing platform has been extended for 17β-estradiol to validate its feasibility in a dual-mode signal readout system based on smartphone imaging and spectrometer. Under the optimal conditions, good linear relationships were achieved based on images (0.05–200 ng/mL) and ratiometric spectra (0.02–200 ng/mL), respectively. Thus, the biosensing platform with portable equipment might provide an economic and viable route for POCT. 17β-Estradiol Point-of-care testing Paper-based microfluidic devices Upconversion nanoparticles Smartphone imaging Ahmad, Waqas verfasserin aut Zhang, Jingui verfasserin aut Wei, Wenya verfasserin aut Yu, Jinghao verfasserin aut Zhang, Wenqian verfasserin aut Chen, Quansheng verfasserin aut Ouyang, Qin verfasserin aut Enthalten in Sensors and actuators <Lausanne> / B Amsterdam [u.a.] : Elsevier Science, 1990 390 Online-Ressource (DE-627)306710358 (DE-600)1500731-5 (DE-576)082435855 0925-4005 nnns volume:390 GBV_USEFLAG_U GBV_ELV SYSFLAG_U SSG-OLC-PHA GBV_ILN_20 GBV_ILN_22 GBV_ILN_23 GBV_ILN_24 GBV_ILN_31 GBV_ILN_32 GBV_ILN_40 GBV_ILN_60 GBV_ILN_62 GBV_ILN_65 GBV_ILN_69 GBV_ILN_70 GBV_ILN_73 GBV_ILN_74 GBV_ILN_90 GBV_ILN_95 GBV_ILN_100 GBV_ILN_101 GBV_ILN_105 GBV_ILN_110 GBV_ILN_150 GBV_ILN_151 GBV_ILN_187 GBV_ILN_213 GBV_ILN_224 GBV_ILN_230 GBV_ILN_370 GBV_ILN_602 GBV_ILN_702 GBV_ILN_2001 GBV_ILN_2003 GBV_ILN_2004 GBV_ILN_2005 GBV_ILN_2007 GBV_ILN_2009 GBV_ILN_2010 GBV_ILN_2011 GBV_ILN_2014 GBV_ILN_2015 GBV_ILN_2020 GBV_ILN_2021 GBV_ILN_2025 GBV_ILN_2026 GBV_ILN_2027 GBV_ILN_2034 GBV_ILN_2044 GBV_ILN_2048 GBV_ILN_2049 GBV_ILN_2050 GBV_ILN_2055 GBV_ILN_2056 GBV_ILN_2059 GBV_ILN_2061 GBV_ILN_2064 GBV_ILN_2106 GBV_ILN_2110 GBV_ILN_2111 GBV_ILN_2112 GBV_ILN_2122 GBV_ILN_2129 GBV_ILN_2143 GBV_ILN_2152 GBV_ILN_2153 GBV_ILN_2190 GBV_ILN_2232 GBV_ILN_2336 GBV_ILN_2470 GBV_ILN_2507 GBV_ILN_4035 GBV_ILN_4037 GBV_ILN_4112 GBV_ILN_4125 GBV_ILN_4242 GBV_ILN_4249 GBV_ILN_4251 GBV_ILN_4305 GBV_ILN_4306 GBV_ILN_4307 GBV_ILN_4313 GBV_ILN_4322 GBV_ILN_4323 GBV_ILN_4324 GBV_ILN_4326 GBV_ILN_4333 GBV_ILN_4334 GBV_ILN_4338 GBV_ILN_4393 GBV_ILN_4700 50.22 Sensorik VZ 35.07 Chemisches Labor chemische Methoden VZ AR 390
language	English
source	Enthalten in Sensors and actuators <Lausanne> / B 390 volume:390
sourceStr	Enthalten in Sensors and actuators <Lausanne> / B 390 volume:390
format_phy_str_mv	Article
bklname	Sensorik Chemisches Labor chemische Methoden
institution	findex.gbv.de
topic_facet	17β-Estradiol Point-of-care testing Paper-based microfluidic devices Upconversion nanoparticles Smartphone imaging
dewey-raw	530
isfreeaccess_bool	false
container_title	Sensors and actuators <Lausanne> / B
authorswithroles_txt_mv	Wu, Jizhong @@aut@@ Ahmad, Waqas @@aut@@ Zhang, Jingui @@aut@@ Wei, Wenya @@aut@@ Yu, Jinghao @@aut@@ Zhang, Wenqian @@aut@@ Chen, Quansheng @@aut@@ Ouyang, Qin @@aut@@
publishDateDaySort_date	2023-01-01T00:00:00Z
hierarchy_top_id	306710358
dewey-sort	3530
id	ELV010204903
language_de	englisch
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author	Wu, Jizhong
spellingShingle	Wu, Jizhong ddc 530 bkl 50.22 bkl 35.07 misc 17β-Estradiol misc Point-of-care testing misc Paper-based microfluidic devices misc Upconversion nanoparticles misc Smartphone imaging Ratiometric upconversion-luminescence in-situ sampling aptasensing platform integrated with smartphone-based device for visual detection of 17β-estradiol
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topic_title	530 620 VZ 50.22 bkl 35.07 bkl Ratiometric upconversion-luminescence in-situ sampling aptasensing platform integrated with smartphone-based device for visual detection of 17β-estradiol 17β-Estradiol Point-of-care testing Paper-based microfluidic devices Upconversion nanoparticles Smartphone imaging
topic	ddc 530 bkl 50.22 bkl 35.07 misc 17β-Estradiol misc Point-of-care testing misc Paper-based microfluidic devices misc Upconversion nanoparticles misc Smartphone imaging
topic_unstemmed	ddc 530 bkl 50.22 bkl 35.07 misc 17β-Estradiol misc Point-of-care testing misc Paper-based microfluidic devices misc Upconversion nanoparticles misc Smartphone imaging
topic_browse	ddc 530 bkl 50.22 bkl 35.07 misc 17β-Estradiol misc Point-of-care testing misc Paper-based microfluidic devices misc Upconversion nanoparticles misc Smartphone imaging
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title	Ratiometric upconversion-luminescence in-situ sampling aptasensing platform integrated with smartphone-based device for visual detection of 17β-estradiol
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title_full	Ratiometric upconversion-luminescence in-situ sampling aptasensing platform integrated with smartphone-based device for visual detection of 17β-estradiol
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author_browse	Wu, Jizhong Ahmad, Waqas Zhang, Jingui Wei, Wenya Yu, Jinghao Zhang, Wenqian Chen, Quansheng Ouyang, Qin
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title_sort	ratiometric upconversion-luminescence in-situ sampling aptasensing platform integrated with smartphone-based device for visual detection of 17β-estradiol
title_auth	Ratiometric upconversion-luminescence in-situ sampling aptasensing platform integrated with smartphone-based device for visual detection of 17β-estradiol
abstract	Rapid initial screening of health markers and food hazards are crucial indicators for ensuring human well-being. Hence, an upconversion-luminescence based aptasensing platform for the in-situ sampling of hazards has been proposed with portable equipment for point-of-care testing (POCT). The aptasensing platform consists of a polymethylmethacrylate needle and a paper-based microfluidic strip patterned with a sacrificial valve, paraffin barriers, and three independent detection zones. The detection zones were assembled with a luminescence resonance energy transfer system constructed by the core/shell/shell structure of upconversion nanoparticles (UCNPs) as the donor, SYBR Green Ⅰ as the acceptor with an aptamer bridge. The biosensing platform has been extended for 17β-estradiol to validate its feasibility in a dual-mode signal readout system based on smartphone imaging and spectrometer. Under the optimal conditions, good linear relationships were achieved based on images (0.05–200 ng/mL) and ratiometric spectra (0.02–200 ng/mL), respectively. Thus, the biosensing platform with portable equipment might provide an economic and viable route for POCT.
abstractGer	Rapid initial screening of health markers and food hazards are crucial indicators for ensuring human well-being. Hence, an upconversion-luminescence based aptasensing platform for the in-situ sampling of hazards has been proposed with portable equipment for point-of-care testing (POCT). The aptasensing platform consists of a polymethylmethacrylate needle and a paper-based microfluidic strip patterned with a sacrificial valve, paraffin barriers, and three independent detection zones. The detection zones were assembled with a luminescence resonance energy transfer system constructed by the core/shell/shell structure of upconversion nanoparticles (UCNPs) as the donor, SYBR Green Ⅰ as the acceptor with an aptamer bridge. The biosensing platform has been extended for 17β-estradiol to validate its feasibility in a dual-mode signal readout system based on smartphone imaging and spectrometer. Under the optimal conditions, good linear relationships were achieved based on images (0.05–200 ng/mL) and ratiometric spectra (0.02–200 ng/mL), respectively. Thus, the biosensing platform with portable equipment might provide an economic and viable route for POCT.
abstract_unstemmed	Rapid initial screening of health markers and food hazards are crucial indicators for ensuring human well-being. Hence, an upconversion-luminescence based aptasensing platform for the in-situ sampling of hazards has been proposed with portable equipment for point-of-care testing (POCT). The aptasensing platform consists of a polymethylmethacrylate needle and a paper-based microfluidic strip patterned with a sacrificial valve, paraffin barriers, and three independent detection zones. The detection zones were assembled with a luminescence resonance energy transfer system constructed by the core/shell/shell structure of upconversion nanoparticles (UCNPs) as the donor, SYBR Green Ⅰ as the acceptor with an aptamer bridge. The biosensing platform has been extended for 17β-estradiol to validate its feasibility in a dual-mode signal readout system based on smartphone imaging and spectrometer. Under the optimal conditions, good linear relationships were achieved based on images (0.05–200 ng/mL) and ratiometric spectra (0.02–200 ng/mL), respectively. Thus, the biosensing platform with portable equipment might provide an economic and viable route for POCT.
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title_short	Ratiometric upconversion-luminescence in-situ sampling aptasensing platform integrated with smartphone-based device for visual detection of 17β-estradiol
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author2	Ahmad, Waqas Zhang, Jingui Wei, Wenya Yu, Jinghao Zhang, Wenqian Chen, Quansheng Ouyang, Qin
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up_date	2024-07-06T17:11:07.494Z
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Ratiometric upconversion-luminescence in-situ sampling aptasensing platform integrated with smartphone-based device for visual detection of 17β-estradiol

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